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Howard Clark

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Procedures

Administration, Intranasal

Disorders

Eosinophilia

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Publications

TOP 3
Roona Deb; Farouk Shakib; Kenneth Reid; Howard Clark
Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D.
Robert B Sim; Howard Clark; Krishnan Hajela; Karine R Mayilyan
Collectins and host defence.
Kenneth B M Reid; Howard Clark; Nades Palaniyar
Surfactant and lung inflammation.

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All Publications

2007: Roona Deb; Farouk Shakib; Kenneth Reid; Howard Clark
Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D.
The Journal of biological chemistry 2007;282(51):36808-19.
2006: Robert B Sim; Howard Clark; Krishnan Hajela; Karine R Mayilyan
Collectins and host defence.
Novartis Foundation symposium 2006;279():170-81; discussion 181-6, 216-9.
2005: Kenneth B M Reid; Howard Clark; Nades Palaniyar
Surfactant and lung inflammation.
Thorax 2005;60(8):620-2.
2005: Howard Clark; Lucy Side Clark
The genetics of neonatal respiratory disease.
Seminars in fetal & neonatal medicine 2005;10(3):271-82.
2005: Nades Palaniyar; Howard Clark; Jeya Nadesalingam; Michael J Shih; Samuel Hawgood; Kenneth B M Reid
Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7352-8.
2005: Rania Jounblat; Howard Clark; Paul Eggleton; Samuel Hawgood; Peter W Andrew; Aras Kadioglu
The role of surfactant protein D in the colonisation of the respiratory tract and onset of bacteraemia during pneumococcal pneumonia.
Respiratory research 2005;6():126.
2004: Samuel Hawgood; Cynthia Brown; Jess Edmondson; Amber Stumbaugh; Lennell Allen; Jon Goerke; Howard Clark; Francis Poulain
Pulmonary collectins modulate strain-specific influenza a virus infection and host responses.
Journal of virology 2004;78(16):8565-72.
2004: Nades Palaniyar; Jeya Nadesalingam; Howard Clark; Michael J Shih; Alister W Dodds; Kenneth B M Reid
Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin.
The Journal of biological chemistry 2004;279(31):32728-36.
2004: Timothy P Hickling; Howard Clark; R Malhotra; Robert B Sim
Collectins and their role in lung immunity.
Journal of leukocyte biology 2004;75(1):27-33.
2003: Nades Palaniyar; Howard Clark; Jeya Nadesalingam; Samuel Hawgood; Kenneth B M Reid
Surfactant protein D binds genomic DNA and apoptotic cells, and enhances their clearance, in vivo.
Annals of the New York Academy of Sciences 2003;1010():471-5.
2003: Howard Clark; Nades Palaniyar; Samuel Hawgood; Kenneth B M Reid
A recombinant fragment of human surfactant protein D reduces alveolar macrophage apoptosis and pro-inflammatory cytokines in mice developing pulmonary emphysema.
Annals of the New York Academy of Sciences 2003;1010():113-6.
2003: Howard Clark; K Reid
The potential of recombinant surfactant protein D therapy to reduce inflammation in neonatal chronic lung disease, cystic fibrosis, and emphysema.
Archives of disease in childhood 2003;88(11):981-4.
2002: Peter Strong; Howard Clark; K Reid
Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(12):1794-800.
2002: Peter Strong; Kenneth B M Reid; Howard Clark
Intranasal delivery of a truncated recombinant human SP-D is effective at down-regulating allergic hypersensitivity in mice sensitized to allergens of Aspergillus fumigatus.
Clinical and experimental immunology 2002;130(1):19-24.
2002: Howard Clark; Nades Palaniyar; Peter Strong; Jess Edmondson; Samuel Hawgood; Kenneth B M Reid
Surfactant protein D reduces alveolar macrophage apoptosis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2892-9.
2001: Taruna Madan; Uday Kishore; M Singh; Peter Strong; Howard Clark; E M Hussain; Kenneth B M Reid; P Usha Sarma
Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens.
The Journal of clinical investigation 2001;107(4):467-75.
1999: Howard Clark; Lennell Allen; E Collins; F Barr; Leland G Dobbs; G Putz; Jon Goerke; Samuel Hawgood
Localization of a candidate surfactant convertase to type II cells, macrophages, and surfactant subfractions.
The American journal of physiology 1999;276(3 Pt 1):L452-8.
1998: F Barr; Howard Clark; Samuel Hawgood
Identification of a putative surfactant convertase in rat lung as a secreted serine carboxylesterase.
The American journal of physiology 1998;274(3 Pt 1):L404-10.