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Luke Clark

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TOP 3
Molly J Crockett; Benedikt Herrmann; Matt Lieberman; Ulrich Müller; Trevor W Robbins; Matthew D Lieberman; Annemieke Apergis-Schoute; Luke Clark
Serotonin modulates striatal responses to fairness and retaliation in humans.
Luke Clark; Alice Egerton; Aaf Benecke; Henrietta Bowden-Jones; Rosanna Michalczuk; David J Nutt; Paola Piccini; Paul R Stokes; Ben J Watson; Kit Wu; Anne Lingford-Hughes
Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity.
Luke Clark; Barnaby D Dunn; Graeme Fairchild; Ruoran Li; Farima Rome; Chelsea M Wright; Michael R F Aitken
Risk-avoidant decision making increased by threat of electric shock.

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All Publications

2013: Molly J Crockett; Benedikt Herrmann; Matt Lieberman; Ulrich Müller; Trevor W Robbins; Matthew D Lieberman; Annemieke Apergis-Schoute; Luke Clark
Serotonin modulates striatal responses to fairness and retaliation in humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(8):3505-13.
2012: Luke Clark; Alice Egerton; Aaf Benecke; Henrietta Bowden-Jones; Rosanna Michalczuk; David J Nutt; Paola Piccini; Paul R Stokes; Ben J Watson; Kit Wu; Anne Lingford-Hughes
Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity.
NeuroImage 2012;63(1):40-6.
2012: Luke Clark; Barnaby D Dunn; Graeme Fairchild; Ruoran Li; Farima Rome; Chelsea M Wright; Michael R F Aitken
Risk-avoidant decision making increased by threat of electric shock.
Psychophysiology 2012;49(10):1436-43.
2012: Antonio Verdejo-Garcia; Luke Clark; Barnaby D Dunn
The role of interoception in addiction: a critical review.
Neuroscience and biobehavioral reviews 2012;36(8):1857-69.
2012: Molly J Crockett; Sharon Morein-Zamir; Annemieke M Apergis-Schoute; Luke Clark; Trevor W Robbins
Serotonin modulates the effects of Pavlovian aversive predictions on response vigor.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(10):2244-52.
2012: Joël Billieux; Yasser Khazaal; Martial Van der Linden; Daniele Zullino; Luke Clark
Trait gambling cognitions predict near-miss experiences and persistence in laboratory slot machine gambling.
British journal of psychology (London, England : 1953) 2012;103(3):412-27.
2012: Luke Clark; Robert Clarke; Ben Crooks; Michael R F Aitken; Barnaby D Dunn
Physiological responses to near-miss outcomes and personal control during simulated gambling.
Journal of gambling studies / co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming 2012;28(1):123-37.
2012: M J Crockett; A Apergis-Schoute; D Campbell-Meikeljohn; H W Chase; Luke Clark; Roshan Cools; O J Robinson; R D Rogers; Jonathan P Roiser; B J Sahakian; Ben Seymour; D Campbell-Meiklejohn; H den Ouden; Trevor W Robbins
Converging evidence for central 5-HT effects in acute tryptophan depletion.
Molecular psychiatry 2012;17(2):121-3.
2012: Luke Clark; Barbara J Sahakian; Oren Boxer; Robert M Bilder
Research methods: cognitive neuropsychological methods.
Handbook of clinical neurology 2012;106():75-87.
2012: Bettina Studer; Trevor W Robbins; Annemieke M Apergis-Schoute; Luke Clark
What are the Odds? The Neural Correlates of Active Choice during Gambling.
Frontiers in neuroscience 2012;6():46.
2012: Luca Passamonti; James Rowe; Annemieke M Apergis-Schoute; Andrew J Calder; Luke Clark; Molly J Crockett; Trevor W Robbins
Effects of acute tryptophan depletion on prefrontal-amygdala connectivity while viewing facial signals of aggression.
Biological psychiatry 2012;71(1):36-43.
2011: Karen D Ersche; Naomi A Fineberg; Emilio V Merlo-Pich; Ulrich Müller; Cinly Ooi; Trevor W Robbins; Jonathan P Roiser; Barbara J Sahakian; Shaila S Shabbir; John Suckling; Sanja Abbott; Luke Clark; Kevin J Craig; Edward T Bullmore
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.
Biological psychiatry 2011;70(8):754-62.
2011: Luke Clark; Alexander Y Dombrovski; Barbara J Sahakian; Cori L Shollenberger; Greg J Siegle; Meryl A Butters; Katalin Szanto
Impairment in risk-sensitive decision-making in older suicide attempters with depression.
Psychology and aging 2011;26(2):321-30.
2011: Bettina Studer; Luke Clark
Place your bets: psychophysiological correlates of decision-making under risk.
Cognitive, affective & behavioral neuroscience 2011;11(2):144-58.
2011: Henry W Chase; Molly J Crockett; Rachel M Msetfi; Robin A Murphy; Luke Clark; Barbara J Sahakian; Trevor W Robbins
5-HT modulation by acute tryptophan depletion of human instrumental contingency judgements.
Psychopharmacology 2011;213(2-3):615-23.
2010: Molly J Crockett; Luke Clark; Matthew D Lieberman; Golnaz Tabibnia; Trevor W Robbins
Impulsive choice and altruistic punishment are correlated and increase in tandem with serotonin depletion.
Emotion (Washington, D.C.) 2010;10(6):855-62.
2010: Molly J Crockett; Luke Clark; Marc D Hauser; Trevor W Robbins
Serotonin selectively influences moral judgment and behavior through effects on harm aversion.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17433-8.
2010: Robert D Rogers; Frederick G Moeller; Alan C Swann; Luke Clark
Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholism.
Alcoholism, clinical and experimental research 2010;34(8):1319-33.
2010: Luke Clark
Decision-making during gambling: an integration of cognitive and psychobiological approaches.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2010;365(1538):319-30.
2009: Andrew J Lawrence; Jason Luty; Nadine A Bogdan; Barbara J Sahakian; Luke Clark
Impulsivity and response inhibition in alcohol dependence and problem gambling.
Psychopharmacology 2009;207(1):163-72.
2009: Chris M Dodds; Luke Clark; Anja Dove; Ralf Regenthal; Frank Baumann; Ed Bullmore; Trevor W Robbins; Ulrich Müller
The dopamine D2 receptor antagonist sulpiride modulates striatal BOLD signal during the manipulation of information in working memory.
Psychopharmacology 2009;207(1):35-45.
2009: Molly J Crockett; Luke Clark; Trevor W Robbins
Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(38):11993-9.
2009: Andrew J Lawrence; Jason Luty; Nadine A Bogdan; Barbara J Sahakian; Luke Clark
Problem gamblers share deficits in impulsive decision-making with alcohol-dependent individuals.
Addiction (Abingdon, England) 2009;104(6):1006-15.
2009: Philip Clatworthy; Simon J G Lewis; Laurent Brichard; Young T Hong; David Izquierdo; Luke Clark; Roshan Cools; Franklin I Aigbirhio; Jean-Claude Baron; Timothy D Fryer; Trevor W Robbins
Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(15):4690-6.
2009: Luke Clark; Andrew J Lawrence; Frances Astley-Jones; Nicola Gray
Gambling near-misses enhance motivation to gamble and recruit win-related brain circuitry.
Neuron 2009;61(3):481-90.
2009: Luke Clark; Samuel Chamberlain; Barbara J Sahakian
Neurocognitive mechanisms in depression: implications for treatment.
Annual review of neuroscience 2009;32():57-74.
2009: Elise E DeVito; Andrew D Blackwell; Luke Clark; Lindsey Kent; Anna Maria Dezsery; Danielle C Turner; Michael R F Aitken; Barbara J Sahakian
Methylphenidate improves response inhibition but not reflection-impulsivity in children with attention deficit hyperactivity disorder (ADHD).
Psychopharmacology 2009;202(1-3):531-9.
2009: Luke Clark; J P Roiser; T W Robbins; B J Sahakian
Disrupted 'reflection' impulsivity in cannabis users but not current or former ecstasy users.
Journal of psychopharmacology (Oxford, England) 2009;23(1):14-22.
2008: Andrew Lawrence; Luke Clark; Jamie Nicole Labuzetta; Barbara J Sahakian; Shai Vyakarnum
The innovative brain.
Nature 2008;456(7219):168-9.
2008: Elise E DeVito; Andrew D Blackwell; Lindsey Kent; Karen D Ersche; Luke Clark; Claire H Salmond; Anna Maria Dezsery; Barbara J Sahakian
The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder.
Biological psychiatry 2008;64(7):636-9.
2008: Joana V Taylor Tavares; Luke Clark; Maura L Furey; Guy B Williams; Barbara J Sahakian; Wayne C Drevets
Neural basis of abnormal response to negative feedback in unmedicated mood disorders.
NeuroImage 2008;42(3):1118-26.
2008: Henry W Chase; Luke Clark; Barbara J Sahakian; Edward T Bullmore; Trevor W Robbins
Dissociable roles of prefrontal subregions in self-ordered working memory performance.
Neuropsychologia 2008;46(11):2650-61.
2008: Molly J Crockett; Luke Clark; Golnaz Tabibnia; Matthew D Lieberman; Trevor W Robbins
Serotonin modulates behavioral reactions to unfairness.
Science (New York, N.Y.) 2008;320(5884):1739.
2008: Chris M Dodds; Ulrich Müller; Luke Clark; Anouk van Loon; Roshan Cools; Trevor W Robbins
Methylphenidate has differential effects on blood oxygenation level-dependent signal related to cognitive subprocesses of reversal learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(23):5976-82.
2008: Luke Clark; A Bechara; H Damasio; Michael R F Aitken; Barbara J Sahakian; Trevor W Robbins
Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making.
Brain : a journal of neurology 2008;131(Pt 5):1311-22.
2008: Henry W Chase; Luke Clark; Catherine E Myers; Mark A Gluck; Barbara J Sahakian; Edward T Bullmore; Trevor W Robbins
The role of the orbitofrontal cortex in human discrimination learning.
Neuropsychologia 2008;46(5):1326-37.
2008: Graham K Murray; Philip R Corlett; Luke Clark; M Pessiglione; Andrew D Blackwell; Garry Honey; Peter B Jones; Edward T Bullmore; Trevor W Robbins; Paul C Fletcher
Substantia nigra/ventral tegmental reward prediction error disruption in psychosis.
Molecular psychiatry 2008;13(3):239, 267-76.
2008: Luke Clark; Barbara J Sahakian
Cognitive neuroscience and brain imaging in bipolar disorder.
Dialogues in clinical neuroscience 2008;10(2):153-63.
2008: Graham K Murray; Luke Clark; Philip R Corlett; Andrew D Blackwell; Roshan Cools; Peter B Jones; Trevor W Robbins; Luise Poustka
Incentive motivation in first-episode psychosis: a behavioural study.
BMC psychiatry 2008;8():34.
2007: Andrew J Lawrence; Andrew D Blackwell; Roger A Barker; Francesca Spagnolo; Luke Clark; Michael R F Aitken; Barbara J Sahakian
Predictors of punding in Parkinson's disease: results from a questionnaire survey.
Movement disorders : official journal of the Movement Disorder Society 2007;22(16):2339-45.
2007: Samuel Chamberlain; Natalia Del Campo; Jonathan Dowson; Ulrich Müller; Luke Clark; Trevor W Robbins; Barbara J Sahakian
Atomoxetine improved response inhibition in adults with attention deficit/hyperactivity disorder.
Biological psychiatry 2007;62(9):977-84.
2007: Joana V Taylor Tavares; Luke Clark; Dara M Cannon; Kristine Erickson; Wayne C Drevets; Barbara J Sahakian
Distinct profiles of neurocognitive function in unmedicated unipolar depression and bipolar II depression.
Biological psychiatry 2007;62(8):917-24.
2007: Jonathan P Roiser; Ulrich Müller; Luke Clark; Barbara J Sahakian
The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2007;10(4):449-61.
2007: Luke Clark; Andrew D Blackwell; Adam R Aron; Danielle C Turner; Jonathan Dowson; Trevor W Robbins; Barbara J Sahakian
Association between response inhibition and working memory in adult ADHD: a link to right frontal cortex pathology?
Biological psychiatry 2007;61(12):1395-401.
2007: Samuel Chamberlain; Naomi A Fineberg; Andrew D Blackwell; Luke Clark; Trevor W Robbins; Barbara J Sahakian
A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania.
Neuropsychologia 2007;45(4):654-62.
2007: Roshan Cools; Simon J G Lewis; Luke Clark; Roger A Barker; Trevor W Robbins
L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(1):180-9.
2006: Jonathan P Roiser; Andrew D Blackwell; Roshan Cools; Luke Clark; David C Rubinsztein; Trevor W Robbins; Barbara J Sahakian
Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(10):2264-72.
2006: Luke Clark; Trevor W Robbins; Karen D Ersche; Barbara J Sahakian
Reflection impulsivity in current and former substance users.
Biological psychiatry 2006;60(5):515-22.
2006: Karen D Ersche; Luke Clark; Mervyn London; Trevor W Robbins; Barbara J Sahakian
Profile of executive and memory function associated with amphetamine and opiate dependence.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(5):1036-47.
2006: Shibley Rahman; Trevor W Robbins; John R Hodges; Mitul A Mehta; Peter J Nestor; Luke Clark; Barbara J Sahakian
Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):651-8.
2006: Samuel Chamberlain; Ulrich Müller; Andrew D Blackwell; Luke Clark; Trevor W Robbins; Barbara J Sahakian
Neurochemical modulation of response inhibition and probabilistic learning in humans.
Science (New York, N.Y.) 2006;311(5762):861-3.
2005: Kristine Erickson; Wayne C Drevets; Luke Clark; Dara M Cannon; Earle E Bain; Carlos A Zarate; Dennis S Charney; Barbara J Sahakian
Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder.
The American journal of psychiatry 2005;162(11):2171-3.
2005: Luke Clark; Jonathan P Roiser; Roshan Cools; David C Rubinsztein; Barbara J Sahakian; Trevor W Robbins
Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity.
Psychopharmacology 2005;182(4):570-8.
2005: Karen D Ersche; Jonathan P Roiser; Luke Clark; Mervyn London; Trevor W Robbins; Barbara J Sahakian
Punishment induces risky decision-making in methadone-maintained opiate users but not in heroin users or healthy volunteers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(11):2115-24.
2005: Luke Clark; Antonina Sarna; Guy M Goodwin
Impairment of executive function but not memory in first-degree relatives of patients with bipolar I disorder and in euthymic patients with unipolar depression.
The American journal of psychiatry 2005;162(10):1980-2.
2005: Ulrich Müller; Luke Clark; Minh L Lam; Rebecca M Moore; C Louise Murphy; Nicola K Richmond; Ranbir S Sandhu; Ingrid A Wilkins; David K Menon; Barbara J Sahakian; Trevor W Robbins
Lack of effects of guanfacine on executive and memory functions in healthy male volunteers.
Psychopharmacology 2005;182(2):205-13.
2005: Karen D Ersche; Paul C Fletcher; S J G Lewis; Luke Clark; G Stocks-Gee; Mervyn London; Julia B Deakin; Trevor W Robbins; Barbara J Sahakian
Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals.
Psychopharmacology 2005;180(4):612-23.
2005: Roshan Cools; Andrew D Blackwell; Luke Clark; Lara Menzies; Sylvia Cox; Trevor W Robbins
Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(7):1362-73.
2004: Luke Clark; Facundo Manes
Social and emotional decision-making following frontal lobe injury.
Neurocase 2004;10(5):398-403.
2004: Danielle C Turner; Luke Clark; Edith Pomarol-Clotet; Peter McKenna; Trevor W Robbins; Barbara J Sahakian
Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(7):1363-73.
2004: Luke Clark; Roshan Cools; Trevor W Robbins
The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning.
Brain and cognition 2004;55(1):41-53.
2004: Danielle C Turner; Luke Clark; Jonathan Dowson; Trevor W Robbins; Barbara J Sahakian
Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder.
Biological psychiatry 2004;55(10):1031-40.
2004: Luke Clark; Guy M Goodwin
State- and trait-related deficits in sustained attention in bipolar disorder.
European archives of psychiatry and clinical neuroscience 2004;254(2):61-8.
2004: Roshan Cools; Luke Clark; Trevor W Robbins
Differential responses in human striatum and prefrontal cortex to changes in object and rule relevance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(5):1129-35.
2003: Danielle C Turner; Trevor W Robbins; Luke Clark; Adam R Aron; Jonathan Dowson; Barbara J Sahakian
Relative lack of cognitive effects of methylphenidate in elderly male volunteers.
Psychopharmacology 2003;168(4):455-64.
2003: Luke Clark; Facundo Manes; Nagui M Antoun; Barbara J Sahakian; Trevor W Robbins
The contributions of lesion laterality and lesion volume to decision-making impairment following frontal lobe damage.
Neuropsychologia 2003;41(11):1474-83.
2003: Danielle C Turner; Trevor W Robbins; Luke Clark; Adam R Aron; Jonathan Dowson; Barbara J Sahakian
Cognitive enhancing effects of modafinil in healthy volunteers.
Psychopharmacology 2003;165(3):260-9.
2002: Roshan Cools; Luke Clark; Adrian M Owen; Trevor W Robbins
Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4563-7.
2002: Facundo Manes; Barbara J Sahakian; Luke Clark; Robert Rogers; Nagui M Antoun; Mike Aitken; Trevor W Robbins
Decision-making processes following damage to the prefrontal cortex.
Brain : a journal of neurology 2002;125(Pt 3):624-39.