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Henrik Clausen

Research Profile

Phenomena

Glycosylation

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Chemicals & Drugs

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Catharina Steentoft; Sergey Y Vakhrushev; Malene B Vester-Christensen; Hans Wandall; Søren Brunak; Sally Dabelsteen; Ramneek Gupta; Hiren J Joshi; Yun Kong; Kirstine Lavrsen; Steven B Levery; Ulla Mandel; Lara Marcos-Silva; Eric Paul Bennett; Nis B Pedersen; Katrine T-B G Schjoldager; Henrik Clausen
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.
Neeley Remmers; Hans Wandall; Fang Yu; Audrey J Lazenby; Erin M Linde; Ulla Mandel; Judy M Anderson; Henrik Clausen; Dominick J Dimaio; Michael A Hollingsworth
Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer.
Sergey Y Vakhrushev; Malene B Vester-Christensen; Eric P Bennett; Henrik Clausen; Catharina Steentoft; Steven B Levery
Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells.

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All Publications

2013: Catharina Steentoft; Sergey Y Vakhrushev; Malene B Vester-Christensen; Hans Wandall; Søren Brunak; Sally Dabelsteen; Ramneek Gupta; Hiren J Joshi; Yun Kong; Kirstine Lavrsen; Steven B Levery; Ulla Mandel; Lara Marcos-Silva; Eric Paul Bennett; Nis B Pedersen; Katrine T-B G Schjoldager; Henrik Clausen
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.
The EMBO journal 2013;32(10):1478-88.
2013: Neeley Remmers; Hans Wandall; Fang Yu; Audrey J Lazenby; Erin M Linde; Ulla Mandel; Judy M Anderson; Henrik Clausen; Dominick J Dimaio; Michael A Hollingsworth
Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(8):1981-93.
2013: Sergey Y Vakhrushev; Malene B Vester-Christensen; Eric P Bennett; Henrik Clausen; Catharina Steentoft; Steven B Levery
Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells.
Molecular & cellular proteomics : MCP 2013;12(4):932-44.
2013: Kirstine Lavrsen; Caroline B Madsen; Ulla Mandel; Anders Elm Pedersen; Morten G Rasch; Anders Woetmann; Niels Odum; Henrik Clausen; Hans Wandall
Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity.
Glycoconjugate journal 2013;30(3):227-36.
2013: Catarina Gomes; Steven B Levery; Ulla Mandel; Andreia Almeida; Francisco M L Amado; Henrik Clausen; Leonor David; José Alexandre Ferreira; João Pinto-de-Sousa; Celso A Reis; Lúcio L Santos; Hugo Santos-Sousa; Tilo Schwientek; Luísa Silva; Hugo Osório
Glycoproteomic analysis of serum from patients with gastric precancerous lesions.
Journal of proteome research 2013;12(3):1454-66.
2013: Natacha Zlocowski; Eric P Bennett; Henrik Clausen; Virginia Lorenz; Gustavo A Nores; Fernando J Irazoqui
An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2.
Biological chemistry 2013;394(1):69-77.
2012: Katrine T-B G Schjoldager; Henrik Clausen
Site-specific protein O-glycosylation modulates proprotein processing - deciphering specific functions of the large polypeptide GalNAc-transferase gene family.
Biochimica et biophysica acta 2012;1820(12):2079-94.
2012: Hans Wandall; Eric P Bennett; Henrik Clausen; John H Hartwig; Joseph E Italiano; Emma C Josefsson; Sunita Patel-Hett; Viktoria Rumjantseva; Anne Louise Tølbøll Sørensen; Karin M Hoffmeister
The origin and function of platelet glycosyltransferases.
Blood 2012;120(3):626-35.
2012: Rita Pinto; Celso A Reis; Ola Söderberg; Joyce Taylor-Papadimitriou; Raquel Almeida; Joy M Burchell; Ana S Carvalho; Henrik Clausen; Tim Conze; Ana Magalhães; Ulla Mandel; Gianfranco Picco; Leonor David
Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.
Journal of cellular and molecular medicine 2012;16(7):1474-84.
2012: Katrine T-B G Schjoldager; Catharina Steentoft; Sergey Y Vakhrushev; Hans Wandall; Yun Kong; Steven B Levery; Ulla Mandel; Aaron S Nudelman; Nis B Pedersen; Eric P Bennett; Henrik Clausen
Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(25):9893-8.
2012: Eric P Bennett; Henrik Clausen; Timothy A Fritz; Thomas A Gerken; Ulla Mandel; Lawrence A Tabak
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.
Glycobiology 2012;22(6):736-56.
2012: Katja Dahlgaard; Anita Jung; Ole Kjaerulff; Klaus Qvortrup; Henrik Clausen; Hans Wandall
Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(18):6987-92.
2012: Chiara Napoletano; Filippo Bellati; Francesca Belleudi; Henrik Clausen; Luigi Frati; Tatsuro Irimura; Luca Pierelli; Hassan Rahimi; Aurelia Rughetti; Hans Wandall; Ilaria G Zizzari; Marianna Nuti
Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
European journal of immunology 2012;42(4):936-45.
2012: Caroline B Madsen; Anders Elm Pedersen; Cecilie Petersen; Søren Buus; Henrik Clausen; Mikkel Harndahl; Kirstine Lavrsen; Hans Wandall
Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response.
PloS one 2012;7(11):e50139.
2012: Emma Arigi; Ola Blixt; Karsten Buschard; Henrik Clausen; Steven B Levery
Design of a covalently bonded glycosphingolipid microarray.
Glycoconjugate journal 2012;29(1):1-12.
2011: Catharina Steentoft; Sergey Y Vakhrushev; Malene B Vester-Christensen; Hans Wandall; Yun Kong; Steven B Levery; Ulla Mandel; Katrine T-B G Schjoldager; Eric P Bennett; Henrik Clausen
Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.
Nature methods 2011;8(11):977-82.
2011: Johannes W Pedersen; Katrine T-B G Schjoldager; Eric P Bennett; Ola Blixt; Henrik Clausen; Emiliano Cló; Andreas P Holmér; Steven B Levery; Morten Meldal; Hans Wandall
Lectin domains of polypeptide GalNAc transferases exhibit glycopeptide binding specificity.
The Journal of biological chemistry 2011;286(37):32684-96.
2011: Natacha Zlocowski; Eric P Bennett; Henrik Clausen; Alberto Jorge; Virginia Lorenz; Gustavo A Nores; Yolanda Núñez; Victor G Sendra; Marcos A Villarreal; Fernando J Irazoqui
Catalytic and glycan-binding abilities of ppGalNAc-T2 are regulated by acetylation.
Biochemical and biophysical research communications 2011;410(1):140-5.
2011: Johannes W Pedersen; Ola Blixt; Eric P Bennett; Mads Agervig Tarp; Imran Dar; Ulla Mandel; Steen S Poulsen; Anders E Pedersen; Susanne Rasmussen; Per Jess; Henrik Clausen; Hans Wandall
Seromic profiling of colorectal cancer patients with novel glycopeptide microarray.
International journal of cancer. Journal international du cancer 2011;128(8):1860-71.
2011: Catharina H M J Van Elssen; Henrik Clausen; Wilfred T V Germeraad; Eric P Bennet; Paul P C A Menheere; Gerard M J Bos; Joris Vanderlocht
Flow cytometry-based assay to evaluate human serum MUC1-Tn antibodies.
Journal of immunological methods 2011;365(1-2):87-94.
2011: Nuno T Marcos; Eric P Bennett; Joana Gomes; Ana Magalhaes; Catarina Gomes; Leonor David; Imran Dar; Charlotte Jeanneau; Shawn DeFrees; Dorrit Krustrup; Lotte K Vogel; Elin H Kure; Joy Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen; Ulla Mandel; Celso A Reis
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.
Frontiers in bioscience (Elite edition) 2011;3():1443-55.
2010: Stjepan K Kracun; Emiliano Cló; Henrik Clausen; Steven B Levery; Knud J Jensen; Stjepan Kresimir Kracun
Random glycopeptide bead libraries for seromic biomarker discovery.
Journal of proteome research 2010;9(12):6705-14.
2010: Katrine T-B G Schjoldager; Malene B Vester-Christensen; Eric P Bennett; Steven B Levery; Tilo Schwientek; Wu Yin; Ola Blixt; Henrik Clausen
O-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids.
The Journal of biological chemistry 2010;285(47):36293-303.
2010: Ola Blixt; Emiliano Cló; Aaron S Nudelman; Kasper Kildegaard Sørensen; Thomas Clausen; Hans Wandall; Philip O Livingston; Henrik Clausen; Knud J Jensen
A high-throughput O-glycopeptide discovery platform for seromic profiling.
Journal of proteome research 2010;9(10):5250-61.
2010: Eric P Bennett; Ya-Wen Chen; Tilo Schwientek; Ulla Mandel; Katrine ter-Borch Gram Schjoldager; Stephen M Cohen; Henrik Clausen
Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.
Glycoconjugate journal 2010;27(4):435-44.
2010: Hans Wandall; Ola Blixt; Mads A Tarp; Johannes W Pedersen; Eric P Bennett; Ulla Mandel; Govind Ragupathi; Philip O Livingston; Michael A Hollingsworth; Joyce Taylor-Papadimitriou; Joy M Burchell; Henrik Clausen
Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes.
Cancer research 2010;70(4):1306-13.
2010: Kentaro Kato; Hideyuki Takeuchi; Akira Kanoh; Naoki Miyahara; Yoko Nemoto-Sasaki; Megumi Morimoto-Tomita; Azusa Matsubara; Yoshimi Ohashi; Michihko Luca Waki; Katsuaki Usami; Ulla Mandel; Henrik Clausen; Nobuaki Higashi; Tatsuro Irimura
Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis.
Glycoconjugate journal 2010;27(2):267-76.
2009: Victor G Sendra; Natacha Zlocowski; Yanina Ditamo; Silvina Copioli; Mads P Tarp; Eric P Bennett; Henrik Clausen; German A Roth; Gustavo A Nores; Fernando J Irazoqui
Glycan bioengineering in immunogen design for tumor T antigen immunotargeting.
Molecular immunology 2009;46(16):3445-53.
2009: B M Vinther; S L Buchardt; Henrik Clausen; D Dahl-Jensen; S J Johnsen; D A Fisher; R M Koerner; D Raynaud; V Lipenkov; K K Andersen; T Blunier; S O Rasmussen; J P Steffensen; A M Svensson
Holocene thinning of the Greenland ice sheet.
Nature 2009;461(7262):385-8.
2009: Mafalda Resende; Sisse B Ditlev; Morten A Nielsen; Sabrina Bodevin; Silas Bruun; Vera V Pinto; Henrik Clausen; Louise Turner; Thor G Theander; Ali Salanti; Madeleine Dahlbäck
Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites.
International journal for parasitology 2009;39(11):1195-204.
2009: Anne Louise Sørensen; Viktoria Rumjantseva; Sara Nayeb-Hashemi; Henrik Clausen; John H Hartwig; Hans Wandall; Karin M Hoffmeister
Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.
Blood 2009;114(8):1645-54.
2008: Kentaro Kato; Hideyuki Takeuchi; Takao Ohki; Michihko Luca Waki; Katsuaki Usami; Helle Hassan; Henrik Clausen; Tatsuro Irimura
A lectin recognizes differential arrangements of O-glycans on mucin repeats.
Biochemical and biophysical research communications 2008;371(4):698-701.
2008: Mads Agervig Tarp; Henrik Clausen
Mucin-type O-glycosylation and its potential use in drug and vaccine development.
Biochimica et biophysica acta 2008;1780(3):546-63.
2007: Ewa Rajpert-De Meyts; S N Poll; I Goukasian; C Jeanneau; Amy S Herlihy; Eric P Bennett; Niels E Skakkebaek; Henrik Clausen; A Giwercman; Ulla Mandel
Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation.
Virchows Archiv : an international journal of pathology 2007;451(4):805-14.
2007: Chiara Napoletano; Aurelia Rughetti; Mads P Agervig Tarp; Julia Coleman; Eric P Bennett; Gianfranco Picco; sale Patrizio; Kaori Denda-Nagai; Tatsuro Irimura; Ulla Mandel; Henrik Clausen; Luigi Frati; Joyce Taylor-Papadimitriou; Joy M Burchell; Marianna Nuti
Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells.
Cancer research 2007;67(17):8358-67.
2007: Ya-Wen Chen; Johannes W Pedersen; Hans Wandall; Steven B Levery; Sandrine Pizette; Henrik Clausen; Mohan Balasubramanian
Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila.
Developmental biology 2007;306(2):736-49.
2007: Peter Norberg; Sven-Olof Olofsson; Mads Agervig Tarp; Henrik Clausen; Tomas Bergström; Jan-Ake Liljeqvist
Glycoprotein I of herpes simplex virus type 1 contains a unique polymorphic tandem-repeated mucin region.
The Journal of general virology 2007;88(Pt 6):1683-8.
2007: Qiyong P Liu; Gerlind Sulzenbacher; Huaiping Yuan; Eric P Bennett; Greg Pietz; Kristen Saunders; Jean Spence; Edward Nudelman; Steven B Levery; Thayer White; John Neveu; William Stratton Lane; Yves Bourne; Martin L Olsson; Bernard Henrissat; Henrik Clausen
Bacterial glycosidases for the production of universal red blood cells.
Nature biotechnology 2007;25(4):454-64.
2007: Hans Wandall; Fernando J Irazoqui; Mads Agervig Tarp; Eric P Bennett; Ulla Mandel; Hideyuki Takeuchi; Kentaro Kato; Tatsuro Irimura; Ganesh Suryanarayanan; Michael A Hollingsworth; Henrik Clausen
The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation.
Glycobiology 2007;17(4):374-87.
2007: Mads Agervig Tarp; Anne Louise Sørensen; Ulla Mandel; Hans Paulsen; Joy M Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen
Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat.
Glycobiology 2007;17(2):197-209.
2007: Susan A Brooks; Tracey M Carter; Eric P Bennett; Henrik Clausen; Ulla Mandel
Immunolocalisation of members of the polypeptide N-acetylgalactosaminyl transferase (ppGalNAc-T) family is consistent with biologically relevant altered cell surface glycosylation in breast cancer.
Acta histochemica 2007;109(4):273-84.
2006: Silvie Cloosen; Janwillem Gratama; Ellen B M Van Leeuwen; Birgit L M G Senden-Gijsbers; Ellis B H Oving; Silvia von Mensdorff-Pouilly; Mads Agervig Tarp; Ulla Mandel; Henrik Clausen; Wilfred T V Germeraad; Gerard M J Bos
Cancer specific Mucin-1 glycoforms are expressed on multiple myeloma.
British journal of haematology 2006;135(4):513-6.
2006: Martin Jinek; Ya-Wen Chen; Henrik Clausen; Mohan Balasubramanian; Elena Conti
Structural insights into the Notch-modifying glycosyltransferase Fringe.
Nature structural & molecular biology 2006;13(10):945-6.
2006: Shawn DeFrees; Zhi-Guang Wang; Ruye Xing; Arthur E Scott; Jin Wang; David Zopf; Dominique L Gouty; Eric R Sjoberg; Krishnasamy Panneerselvam; Els C M Brinkman-Van der Linden; Robert J Bayer; Mads Agervig Tarp; Henrik Clausen
GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli.
Glycobiology 2006;16(9):833-43.
2006: Kentaro Kato; Charlotte Jeanneau; Mads Agervig Tarp; Anna Benet-Pagès; Bettina Lorenz-Depiereux; Eric P Bennett; Ulla Mandel; Tim M Strom; Henrik Clausen
Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation.
The Journal of biological chemistry 2006;281(27):18370-7.
2006: Robert Sewell; Malin Bäckström; Martin Dalziel; Steven Gschmeissner; Hasse Karlsson; Thomas Noll; Jochem Gätgens; Henrik Clausen; Gunnar Hansson; Joy M Burchell; Joyce Taylor-Papadimitriou
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.
The Journal of biological chemistry 2006;281(6):3586-94.
2006: Anne Louise Sørensen; Celso A Reis; Mads Agervig Tarp; Ulla Mandel; Kavitha Ramachandran; Vasanthi Sankaranarayanan; Tilo Schwientek; Ros Graham; Joyce Taylor-Papadimitriou; Michael A Hollingsworth; Joy M Burchell; Henrik Clausen
Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.
Glycobiology 2006;16(2):96-107.
2006: Ellen B M Van Leeuwen; Silvie Cloosen; Birgit L M G Senden-Gijsbers; M Agervig Tarp; Ulla Mandel; Henrik Clausen; Menzo J E Havenga; M-T Duffour; Juan Jesus Garcia Vallejo; Wilfred T V Germeraad; Gerard M J Bos
Expression of aberrantly glycosylated tumor mucin-1 on human DC after transduction with a fiber-modified adenoviral vector.
Cytotherapy 2006;8(1):24-35.
2005: Matthew D Fuller; Tilo Schwientek; Hans Wandall; Johannes W Pedersen; Henrik Clausen; Steven B Levery
Structure elucidation of neutral, di-, tri-, and tetraglycosylceramides from High Five cells: identification of a novel (non-arthro-series) glycosphingolipid pathway.
Glycobiology 2005;15(12):1286-301.
2005: Fernando J Irazoqui; Magdolna M Vozari-Hampe; Ricardo Lardone; Marcos A Villarreal; Victor G Sendra; Guillermo G Montich; Vera M Trindade; Henrik Clausen; Gustavo A Nores
Fine carbohydrate recognition of Euphorbia milii lectin.
Biochemical and biophysical research communications 2005;336(1):14-21.
2005: Aurelia Rughetti; Ilenia Pellicciotta; Mauro Biffoni; Malin Bäckström; Thomas Link; Eric P Bennet; Henrik Clausen; Thomas Noll; Gunnar Hansson; Joy M Burchell; Luigi Frati; Joyce Taylor-Papadimitriou; Marianna Nuti
Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7764-72.
2005: Hans Wandall; Sandrine Pizette; Johannes W Pedersen; Heather Eichert; Steven B Levery; Ulla Mandel; Mohan Balasubramanian; Henrik Clausen
Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo.
The Journal of biological chemistry 2005;280(6):4858-63.
2004: Nuno T Marcos; Sandra Pinho; Catarina Grandela; Andrea Cruz; Bénédicte Samyn-Petit; Anne Harduin-Lepers; Raquel Almeida; Filipe Silva; Vanessa Morais; Julia Costa; Jan Kihlberg; Henrik Clausen; Celso A Reis
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen.
Cancer research 2004;64(19):7050-7.
2004: Arron Mungul; Lucienne Cooper; Inka Brockhausen; Kenneth Ryder; Ulla Mandel; Henrik Clausen; Aurelia Rughetti; David W Miles; Joyce Taylor-Papadimitriou; Joy M Burchell
Sialylated core 1 based O-linked glycans enhance the growth rate of mammary carcinoma cells in MUC1 transgenic mice.
International journal of oncology 2004;25(4):937-43.
2004: Kristina Mårdberg; Kristina Nyström; Mads Agervig Tarp; Edward Trybala; Henrik Clausen; Tomas Bergström; Sven-Olof Olofsson
Basic amino acids as modulators of an O-linked glycosylation signal of the herpes simplex virus type 1 glycoprotein gC: functional roles in viral infectivity.
Glycobiology 2004;14(7):571-81.
2003: Leo Kinarsky; Ganesh Suryanarayanan; Om Prakash; Hans Paulsen; Henrik Clausen; Franz-Georg Hanisch; Michael A Hollingsworth; Simon Sherman
Conformational studies on the MUC1 tandem repeat glycopeptides: implication for the enzymatic O-glycosylation of the mucin protein core.
Glycobiology 2003;13(12):929-39.
2003: Cecile Tétaud; Thomas Falguières; Karine Carlier; Yann Lécluse; Julie GARIBAL; Dominique Coulaud; Pierre Busson; Rudi Steffensen; Henrik Clausen; Ludger Johannes; Joëlle Wiels
Two distinct Gb3/CD77 signaling pathways leading to apoptosis are triggered by anti-Gb3/CD77 mAb and verotoxin-1.
The Journal of biological chemistry 2003;278(46):45200-8.
2003: Nuno T Marcos; Andrea Cruz; Filipe Silva; Raquel Almeida; Leonor David; Ulla Mandel; Henrik Clausen; Silvia von Mensdorff-Pouilly; Celso A Reis
Polypeptide GalNAc-transferases, ST6GalNAc-transferase I, and ST3Gal-transferase I expression in gastric carcinoma cell lines.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(6):761-71.
2003: Hans Wandall; Johannes W Pedersen; Chaeho Park; Steven B Levery; Sandrine Pizette; Mohan Balasubramanian; Tilo Schwientek; Henrik Clausen
Drosophila egghead encodes a beta 1,4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac.
The Journal of biological chemistry 2003;278(3):1411-4.
2002: Hideyuki Takeuchi; Kentaro Kato; Kaori Denda-Nagai; Franz-Georg Hanisch; Henrik Clausen; Tatsuro Irimura
The epitope recognized by the unique anti-MUC1 monoclonal antibody MY.1E12 involves sialyl alpha 2-3galactosyl beta 1-3N-acetylgalactosaminide linked to a distinct threonine residue in the MUC1 tandem repeat.
Journal of immunological methods 2002;270(2):199-209.
2002: Hideyuki Takeuchi; Kentaro Kato; Helle Hassan; Henrik Clausen; Tatsuro Irimura
O-GalNAc incorporation into a cluster acceptor site of three consecutive threonines. Distinct specificity of GalNAc-transferase isoforms.
European journal of biochemistry / FEBS 2002;269(24):6173-83.
2002: Tilo Schwientek; Birgit Keck; Steven B Levery; Mads A Jensen; Johannes W Pedersen; Hans Wandall; Mark R Stroud; Mohan Balasubramanian; Margarida Amado; Henrik Clausen
The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis.
The Journal of biological chemistry 2002;277(36):32421-9.
2002: Tilo Schwientek; Eric P Bennett; Carlos Flores; John Thacker; Martin Hollmann; Celso A Reis; Jane Behrens; Ulla Mandel; Birgit Keck; Mireille A Schäfer; Kim F Haselmann; Roman A Zubarev; Peter Roepstorff; Joy M Burchell; Joyce Taylor-Papadimitriou; Michael A Hollingsworth; Henrik Clausen
Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.
The Journal of biological chemistry 2002;277(25):22623-38.
2001: S K George; Tilo Schwientek; Björn Holm; Celso A Reis; Henrik Clausen; Jan Kihlberg
Chemoenzymatic synthesis of sialylated glycopeptides derived from mucins and T-cell stimulating peptides.
Journal of the American Chemical Society 2001;123(45):11117-25.
2001: Koichi Kato; Hideaki Takeuchi; Akira Kanoh; Ulla Mandel; Helle Hassan; Henrik Clausen; Tatsuro Irimura
N-acetylgalactosamine incorporation into a peptide containing consecutive threonine residues by UDP-N-acetyl-D-galactosaminide:polypeptide N-acetylgalactosaminyltransferases.
Glycobiology 2001;11(10):821-9.
2001: Koichi Kato; Hideaki Takeuchi; N Miyahara; Akira Kanoh; Helle Hassan; Henrik Clausen; Tatsuro Irimura
Distinct orders of GalNAc incorporation into a peptide with consecutive threonines.
Biochemical and biophysical research communications 2001;287(1):110-5.
2001: Jørgen Vinten; Marianne Voldstedlund; Henrik Clausen; K Christiansen; J Carlsen; Jørgen Tranum-Jensen
A 60-kDa protein abundant in adipocyte caveolae.
Cell and tissue research 2001;305(1):99-106.
2001: Kim F Haselmann; Bogdan A Budnik; Jesper V Olsen; Michael L Nielsen; C A Reis; Henrik Clausen; A H Johnsen; Roman A Zubarev
Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry.
Analytical chemistry 2001;73(13):2998-3005.
2001: Martin Dalziel; C Whitehouse; I McFarlane; Inka Brockhausen; Steven Gschmeissner; Tilo Schwientek; Henrik Clausen; Joy M Burchell; Joyce Taylor-Papadimitriou
The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.
The Journal of biological chemistry 2001;276(14):11007-15.
2001: Ekaterina Mirgorodskaya; Helle Hassan; Henrik Clausen; Peter Roepstorff
Mass spectrometric determination of O-glycosylation sites using beta-elimination and partial acid hydrolysis.
Analytical chemistry 2001;73(6):1263-9.
2000: Helle Hassan; Celso A Reis; Eric P Bennett; Ekaterina Mirgorodskaya; Peter Roepstorff; Michael A Hollingsworth; Joy M Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen
The lectin domain of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities.
The Journal of biological chemistry 2000;275(49):38197-205.
2000: Marlene Biller; Kristina Mårdberg; Helle Hassan; Henrik Clausen; Anders Bolmstedt; Tomas Bergström; Sven-Olof Olofsson
Early steps in O-linked glycosylation and clustered O-linked glycans of herpes simplex virus type 1 glycoprotein C: effects on glycoprotein properties.
Glycobiology 2000;10(12):1259-69.
2000: K Brückner; L Perez; Henrik Clausen; S Cohen
Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.
Nature 2000;406(6794):411-5.
2000: Rudi Steffensen; Karine Carlier; Joëlle Wiels; Steven B Levery; Mark R Stroud; B Cedergren; B Nilsson Sojka; Eric P Bennett; C Jersild; Henrik Clausen
Cloning and expression of the histo-blood group Pk UDP-galactose: Ga1beta-4G1cbeta1-cer alpha1, 4-galactosyltransferase. Molecular genetic basis of the p phenotype.
The Journal of biological chemistry 2000;275(22):16723-9.
2000: Tilo Schwientek; J C Yeh; Steven B Levery; Birgit Keck; Gerard F M Merkx; AG van Kessel; M Fukuda; Henrik Clausen
Control of O-glycan branch formation. Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n-acetylglucosaminyltransferase.
The Journal of biological chemistry 2000;275(15):11106-13.
2000: Celso A Reis; Leonor David; Filipa Carvalho; Ulla Mandel; Carme de Bolós; Ekaterina Mirgorodskaya; Henrik Clausen; Manuel Sobrinho-Simões
Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2000;48(3):377-88.
2000: Margarida Amado; Eric P Bennett; Fátima Carneiro; Henrik Clausen
Characterization of the histo-blood group O(2) gene and its protein product.
Vox sanguinis 2000;79(4):219-26.
1999: Margarida Amado; Raquel Almeida; Tilo Schwientek; Henrik Clausen
Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.
Biochimica et biophysica acta 1999;1473(1):35-53.
1999: Joy M Burchell; R Poulsom; A Hanby; C Whitehouse; Lucienne Cooper; Henrik Clausen; David Miles; Joyce Taylor-Papadimitriou
An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas.
Glycobiology 1999;9(12):1307-11.
1999: Eric P Bennett; Helle Hassan; Michael A Hollingsworth; Henrik Clausen
A novel human UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, GalNAc-T7, with specificity for partial GalNAc-glycosylated acceptor substrates.
FEBS letters 1999;460(2):226-30.
1999: Raquel Almeida; Steven B Levery; Ulla Mandel; H Kresse; Tilo Schwientek; Eric P Bennett; Henrik Clausen
Cloning and expression of a proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I. A seventh member of the human beta4-galactosyltransferase gene family.
The Journal of biological chemistry 1999;274(37):26165-71.
1999: Eric P Bennett; Helle Hassan; Ulla Mandel; Michael A Hollingsworth; Naoaki Akisawa; Y Ikematsu; Gerard F M Merkx; AG van Kessel; Sven-Olof Olofsson; Henrik Clausen
Cloning and characterization of a close homologue of human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase-T3, designated GalNAc-T6. Evidence for genetic but not functional redundancy.
The Journal of biological chemistry 1999;274(36):25362-70.
1999: S Iida; Hideaki Takeuchi; Helle Hassan; Henrik Clausen; Tatsuro Irimura
Incorporation of N-acetylgalactosamine into consecutive threonine residues in MUC2 tandem repeat by recombinant human N-acetyl-D-galactosamine transferase-T1, T2 and T3.
FEBS letters 1999;449(2-3):230-4.
1999: Ekaterina Mirgorodskaya; Helle Hassan; Hans Wandall; Henrik Clausen; Peter Roepstorff
Partial vapor-phase hydrolysis of peptide bonds: A method for mass spectrometric determination of O-glycosylated sites in glycopeptides.
Analytical biochemistry 1999;269(1):54-65.
1999: M Ujita; J McAuliffe; Misa Suzuki; Ole Hindsgaul; Henrik Clausen; M N Fukuda; Michiko N Fukuda
Regulation of I-branched poly-N-acetyllactosamine synthesis. Concerted actions by I-extension enzyme, I-branching enzyme, and beta1,4-galactosyltransferase I.
The Journal of biological chemistry 1999;274(14):9296-304.
1999: Celso A Reis; Leonor David; Pelayo Correa; Fátima Carneiro; Carme de Bolós; E Garcia; Ulla Mandel; Henrik Clausen; Manuel Sobrinho-Simões
Intestinal metaplasia of human stomach displays distinct patterns of mucin (MUC1, MUC2, MUC5AC, and MUC6) expression.
Cancer research 1999;59(5):1003-7.
1999: Tilo Schwientek; M Nomoto; Steven B Levery; Gerard F M Merkx; AG van Kessel; Eric P Bennett; Michael A Hollingsworth; Henrik Clausen
Control of O-glycan branch formation. Molecular cloning of human cDNA encoding a novel beta1,6-N-acetylglucosaminyltransferase forming core 2 and core 4.
The Journal of biological chemistry 1999;274(8):4504-12.
1999: Ulla Mandel; Helle Hassan; MH Therkildsen; Jørgen Rygaard; M H Jakobsen; Birgitte Ravn Juhl; Erik Dabelsteen; Henrik Clausen
Expression of polypeptide GalNAc-transferases in stratified epithelia and squamous cell carcinomas: immunohistological evaluation using monoclonal antibodies to three members of the GalNAc-transferase family.
Glycobiology 1999;9(1):43-52.
1998: M Ujita; J McAuliffe; Tilo Schwientek; Raquel Almeida; Ole Hindsgaul; Henrik Clausen; Michiko N Fukuda
Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase.
The Journal of biological chemistry 1998;273(52):34843-9.
1998: Eric P Bennett; Helle Hassan; Ulla Mandel; Ekaterina Mirgorodskaya; Peter Roepstorff; Joy M Burchell; Joyce Taylor-Papadimitriou; Michael A Hollingsworth; Gerard F M Merkx; AG van Kessel; Hans Eiberg; Rudi Steffensen; Henrik Clausen
Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat.
The Journal of biological chemistry 1998;273(46):30472-81.
1998: Tilo Schwientek; Raquel Almeida; Steven B Levery; Eric H Holmes; E Bennett; Henrik Clausen
Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesis.
The Journal of biological chemistry 1998;273(45):29331-40.
1998: L Kirnarsky; M Nomoto; Y Ikematsu; Helle Hassan; Eric P Bennett; R L Cerny; Henrik Clausen; Michael A Hollingsworth; Simon Sherman
Structural analysis of peptide substrates for mucin-type O-glycosylation.
Biochemistry 1998;37(37):12811-7.
1998: Eric P Bennett; D O Weghuis; Gerard F M Merkx; AG van Kessel; Hans Eiberg; Henrik Clausen
Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase family.
Glycobiology 1998;8(6):547-55.
1998: Margarida Amado; Raquel Almeida; Fátima Carneiro; Steven B Levery; Eric H Holmes; M Nomoto; Michael A Hollingsworth; Helle Hassan; Tilo Schwientek; PA Nielsen; Eric P Bennett; Henrik Clausen
A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family.
The Journal of biological chemistry 1998;273(21):12770-8.
1998: Margarida Amado; Fátima Carneiro; Mário Seixas; Henrik Clausen; Manuel Sobrinho-Simões
Dimeric sialyl-Le(x) expression in gastric carcinoma correlates with venous invasion and poor outcome.
Gastroenterology 1998;114(3):462-70.
1998: Celso A Reis; T Sørensen; Ulla Mandel; Leonor David; Ekaterina Mirgorodskaya; Peter Roepstorff; Jan Kihlberg; J E Hansen; Henrik Clausen
Development and characterization of an antibody directed to an alpha-N-acetyl-D-galactosamine glycosylated MUC2 peptide.
Glycoconjugate journal 1998;15(1):51-62.
1998: Celso A Reis; Helle Hassan; Eric P Bennett; Henrik Clausen
Characterization of a panel of monoclonal antibodies using GalNAc glycosylated peptides and recombinant MUC1.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1998;19 Suppl 1():127-33.
1998: S Röttger; J White; Hans Wandall; J C Olivo; A Stark; Eric P Bennett; C Whitehouse; E G Berger; Henrik Clausen; T Nilsson
Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus.
Journal of cell science 1998;111 ( Pt 1)():45-60.
1997: Raquel Almeida; Margarida Amado; Leonor David; Steven B Levery; Eric H Holmes; Gerard F M Merkx; AG van Kessel; E Rygaard; Helle Hassan; E Bennett; Henrik Clausen
A family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3.
The Journal of biological chemistry 1997;272(51):31979-91.
1997: ME Sutherlin; Isao Nishimori; Thomas Caffrey; Eric P Bennett; Helle Hassan; Ulla Mandel; D Mack; Takeshi Iwamura; Henrik Clausen; Michael A Hollingsworth
Expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases in adenocarcinoma cell lines.
Cancer research 1997;57(21):4744-8.
1997: Hans Wandall; Helle Hassan; Ekaterina Mirgorodskaya; A K Kristensen; Peter Roepstorff; Eric P Bennett; PA Nielsen; Michael A Hollingsworth; Joy M Burchell; Joyce Taylor-Papadimitriou; Henrik Clausen
Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.
The Journal of biological chemistry 1997;272(38):23503-14.
1997: PA Nielsen; Eric P Bennett; Hans Wandall; MH Therkildsen; Jens Hannibal; Henrik Clausen
Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B.
Glycobiology 1997;7(3):413-9.
1997: Celso A Reis; Leonor David; PA Nielsen; Henrik Clausen; K Mirgorodskaya; P Roepstorff; Manuel Sobrinho-Simões
Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody.
International journal of cancer. Journal international du cancer 1997;74(1):112-21.
1997: PA Nielsen; Ulla Mandel; MH Therkildsen; V Ravn; Leonor David; Celso A Reis; Hans Wandall; Erik Dabelsteen; Henrik Clausen
Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas.
Cancer research 1997;57(4):634-40.
1997: Filipa Carvalho; Raquel Seruca; Leonor David; António Amorim; Mário Seixas; E Bennett; Henrik Clausen; Manuel Sobrinho-Simões
MUC1 gene polymorphism and gastric cancer--an epidemiological study.
Glycoconjugate journal 1997;14(1):107-11.
1996: PA Nielsen; Ulla Mandel; MH Therkildsen; Henrik Clausen
Differential expression of human high-molecular-weight salivary mucin (MG1) and low-molecular-weight salivary mucin (MG2).
Journal of dental research 1996;75(11):1820-6.
1996: Henrik Clausen; Eric P Bennett
A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation.
Glycobiology 1996;6(6):635-46.
1996: Eric P Bennett; Helle Hassan; Henrik Clausen
cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3.
The Journal of biological chemistry 1996;271(29):17006-12.
1995: T Sørensen; T White; Hans Wandall; A K Kristensen; Peter Roepstorff; Henrik Clausen
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Identification and separation of two distinct transferase activities.
The Journal of biological chemistry 1995;270(41):24166-73.
1995: T White; Eric P Bennett; K Takio; T Sørensen; N Bonding; Henrik Clausen
Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.
The Journal of biological chemistry 1995;270(41):24156-65.
1995: Eric P Bennett; R Steffensen; Henrik Clausen; D O Weghuis; A Geurts van Kessel
Genomic cloning of the human histo-blood group ABO locus.
Biochemical and biophysical research communications 1995;211(1):347.
1995: Eric P Bennett; R Steffensen; Henrik Clausen; D O Weghuis; A G van Kessel
Genomic cloning of the human histo-blood group ABO locus.
Biochemical and biophysical research communications 1995;206(1):318-25.
1994: Fátima Carneiro; Margarida Amado; L David; Henrik Clausen; Manuel Sobrinho-Simões
Glycosylation features of gastric carcinoma initiation and progression. A review with emphasis on simple mucin-type carbohydrates and histo-blood group antigens of the Lewis system.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1994;3 Suppl 2():39-46.
1994: M R Stroud; Steven B Levery; S Mårtensson; M E Salyan; Henrik Clausen; S Hakomori
Human tumor-associated Le(a)-Le(x) hybrid carbohydrate antigen IV3(Gal beta 1-->3[Fuc alpha 1-->4]GlcNAc)III3FucnLc4 defined by monoclonal antibody 43-9F: enzymatic synthesis, structural characterization, and comparative reactivity with various antibodies.
Biochemistry 1994;33(35):10672-80.
1994: Ulla Mandel; B Gaggero; Jesper Reibel; MH Therkildsen; Erik Dabelsteen; Henrik Clausen
Oncofetal fibronectins in oral carcinomas: correlation of two different types.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1994;102(9):695-702.
1994: Peter Meldgaard; E H Holmes; Eric P Bennett; Henrik Clausen; J Zeuthen; Hans Wolf; Torben F Orntoft
Blood group ABO-related glycosylation of urothelial cell lines: immunocytological, enzymatic, and genetic characterization.
Cancer research 1994;54(9):2440-7.
1994: Fátima Carneiro; L Santos; Leonor David; Erik Dabelsteen; Henrik Clausen; Manuel Sobrinho-Simões
T (Thomsen-Friedenreich) antigen and other simple mucin-type carbohydrate antigens in precursor lesions of gastric carcinoma.
Histopathology 1994;24(2):105-13.
1994: A M Sørensen; Claus Nielsen; M Arendrup; Henrik Clausen; Jens Ole Nielsen; Eduardo Osinaga; A Roseto; John-Erik Stig Hansen
Neutralization epitopes on HIV pseudotyped with HTLV-I: conservation of carbohydrate epitopes.
Journal of acquired immune deficiency syndromes 1994;7(2):116-23.
1994: Henrik Clausen; Eric P Bennett; N Grunnet
Molecular genetics of ABO histo-blood groups.
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 1994;1(2):79-89.
1994: N Grunnet; R Steffensen; Eric P Bennett; Henrik Clausen
Evaluation of histo-blood group ABO genotyping in a Danish population: frequency of a novel O allele defined as O2.
Vox sanguinis 1994;67(2):210-5.
1993: Leonor David; D Leitao; M Sobrinho-Simoes; Eric P Bennett; T White; Ulla Mandel; Erik Dabelsteen; Henrik Clausen
Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals.
Cancer research 1993;53(22):5494-500.
1993: D Jeppe-Jensen; Henrik Clausen; I M Leigh; E B Lane; E Dabelsteen
Three monoclonal antibodies differentiate human from murine epidermis.
Epithelial cell biology 1993;2(3):100-6.
1993: M Arendrup; Anders Sönnerborg; B Svennerholm; Lennart Akerblom; Claus Nielsen; Henrik Clausen; Sven-Olof Olofsson; Jens Ole Nielsen; John-Erik Stig Hansen
Neutralizing antibody response during human immunodeficiency virus type 1 infection: type and group specificity and viral escape.
The Journal of general virology 1993;74 ( Pt 5)():855-63.
1992: Niels Christian Langkilde; H Wolf; Henrik Clausen; Torben F Orntoft
Localization and identification of T-(Gal beta 1-3GalNAc alpha 1-O-R) and T-like antigens in experimental rat bladder cancer.
The Journal of urology 1992;148(4):1279-84.
1992: Niels Christian Langkilde; H Wolf; Henrik Clausen; Torben F Orntoft
Human urinary bladder carcinoma glycoconjugates expressing T-(Gal beta(1-3)GalNAc alpha 1-O-R) and T-like antigens: a comparative study using peanut agglutinin and poly- and monoclonal antibodies.
Cancer research 1992;52(18):5030-6.
1992: A Stapleton; E Nudelman; Henrik Clausen; S Hakomori; Walter E Stamm
Binding of uropathogenic Escherichia coli R45 to glycolipids extracted from vaginal epithelial cells is dependent on histo-blood group secretor status.
The Journal of clinical investigation 1992;90(3):965-72.
1992: Ulla Mandel; M Hamilton Therkildsen; Jesper Reibel; B Sweeney; H Matsuura; S Hakomori; Erik Dabelsteen; Henrik Clausen
Cancer-associated changes in glycosylation of fibronectin. Immunohistological localization of oncofetal fibronectin defined by monoclonal antibodies.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1992;100(9):817-26.
1992: Ulla Mandel; Niels Christian Langkilde; Torben F Orntoft; MH Therkildsen; J Karkov; Jesper Reibel; T White; Henrik Clausen; Erik Dabelsteen
Expression of histo-blood-group-A/B-gene-defined glycosyltransferases in normal and malignant epithelia: correlation with A/B-carbohydrate expression.
International journal of cancer. Journal international du cancer 1992;52(1):7-12.
1992: J J Thorn; Steven B Levery; M E Salyan; M R Stroud; B Cedergren; B Nilsson; S Hakomori; Henrik Clausen
Structural characterization of x2 glycosphingolipid, its extended form, and its sialosyl derivatives: accumulation associated with the rare blood group p phenotype.
Biochemistry 1992;31(28):6509-17.
1992: Niels Christian Langkilde; H Wolf; Henrik Clausen; T Kjeldsen; Torben F Orntoft
Nuclear volume and expression of T-antigen, sialosyl-Tn-antigen, and Tn-antigen in carcinoma of the human bladder. Relation to tumor recurrence and progression.
Cancer 1992;69(1):219-27.
1992: Henrik Clausen; Eric P Bennett; Erik Dabelsteen
Carbohydrates of the cell surface: molecular aspects of glycosyltransferases and their genes.
APMIS. Supplementum 1992;27():9-17.
1992: Leonor David; J M Nesland; Henrik Clausen; Fátima Carneiro; Manuel Sobrinho-Simões
Simple mucin-type carbohydrate antigens (Tn, sialosyl-Tn and T) in gastric mucosa, carcinomas and metastases.
APMIS. Supplementum 1992;27():162-72.
1992: Erik Dabelsteen; Henrik Clausen; Ulla Mandel
Carbohydrate changes in squamous cell carcinomas.
APMIS. Supplementum 1992;27():130-8.
1992: John-Erik Stig Hansen; Henrik Clausen; S L Hu; Jens Ole Nielsen; Sven-Olof Olofsson
An O-linked carbohydrate neutralization epitope of HIV-1 gp 120 is expressed by HIV-1 env gene recombinant vaccinia virus.
Archives of virology 1992;126(1-4):11-20.
1991: John-Erik Stig Hansen; Claus Nielsen; M Arendrup; Sven-Olof Olofsson; Lars Mathiesen; Jens Ole Nielsen; Henrik Clausen
Broadly neutralizing antibodies targeted to mucin-type carbohydrate epitopes of human immunodeficiency virus.
Journal of virology 1991;65(12):6461-7.
1991: Ulla Mandel; O W Petersen; H Sørensen; P Vedtofte; S Hakomori; Henrik Clausen; Erik Dabelsteen
Simple mucin-type carbohydrates in oral stratified squamous and salivary gland epithelia.
The Journal of investigative dermatology 1991;97(4):713-21.
1991: John-Erik Stig Hansen; Claus Nielsen; Henrik Clausen; L R Mathiesen; Jens Ole Nielsen
Effect of anti-carbohydrate antibodies on HIV infection in a monocytic cell line (U937).
Antiviral research 1991;16(3):233-42.
1991: Erik Dabelsteen; Henrik Clausen; Ulla Mandel
Aberrant glycosylation in oral malignant and premalignant lesions.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1991;20(8):361-8.
1991: M Arendrup; John-Erik Stig Hansen; Henrik Clausen; Claus Nielsen; L R Mathiesen; Jens Ole Nielsen
Antibody to histo-blood group A antigen neutralizes HIV produced by lymphocytes from blood group A donors but not from blood group B or O donors.
AIDS (London, England) 1991;5(4):441-4.
1991: Torben F Orntoft; E H Holmes; P Johnson; S Hakomori; Henrik Clausen
Differential tissue expression of the Lewis blood group antigens: enzymatic, immunohistologic, and immunochemical evidence for Lewis a and b antigen expression in Le(a-b-) individuals.
Blood 1991;77(6):1389-96.
1991: Torben F Orntoft; P Greenwell; Henrik Clausen; W M Watkins
Regulation of the oncodevelopmental expression of type 1 chain ABH and Lewis(b) blood group antigens in human colon by alpha-2-L-fucosylation.
Gut 1991;32(3):287-93.
1991: Ulla Mandel; T F Orntoft; E H Holmes; H Sørensen; Henrik Clausen; S Hakomori; Erik Dabelsteen
Lewis blood group antigens in salivary glands and stratified epithelium: lack of regulation of Lewis antigen expression in ductal and buccal mucosal lining epithelia.
Vox sanguinis 1991;61(3):205-14.
1990: Ulla Mandel; T White; J Karkov; S Hakomori; Henrik Clausen; Erik Dabelsteen
Expression of the histo-blood group ABO gene defined glycosyltransferases in epithelial tissues.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1990;19(6):251-6.
1990: John-Erik Stig Hansen; Henrik Clausen; Claus Nielsen; L S Teglbjaerg; L L Hansen; C M Nielsen; E Dabelsteen; Lars Mathiesen; S I Hakomori; Jens Ole Nielsen
Inhibition of human immunodeficiency virus (HIV) infection in vitro by anticarbohydrate monoclonal antibodies: peripheral glycosylation of HIV envelope glycoprotein gp120 may be a target for virus neutralization.
Journal of virology 1990;64(6):2833-40.
1990: Fumiichiro Yamamoto; Henrik Clausen; T White; J Marken; S Hakomori
Molecular genetic basis of the histo-blood group ABO system.
Nature 1990;345(6272):229-33.
1990: T White; Ulla Mandel; Torben F Orntoft; Erik Dabelsteen; J Karkov; M Kubeja; S Hakomori; Henrik Clausen
Murine monoclonal antibodies directed to the human histo-blood group A transferase (UDP-GalNAc:Fuc alpha 1----2Gal alpha 1----3-N-acetylgalactosaminyltransferase) and the presence therein of N-linked histo-blood group A determinant.
Biochemistry 1990;29(11):2740-7.
1990: A K Singhal; Torben F Orntoft; E Nudelman; S Nance; L Schibig; M R Stroud; Henrik Clausen; S Hakomori
Profiles of Lewisx-containing glycoproteins and glycolipids in sera of patients with adenocarcinoma.
Cancer research 1990;50(5):1375-80.
1990: Fumiichiro Yamamoto; J Marken; T Tsuji; T White; Henrik Clausen; S Hakomori
Cloning and characterization of DNA complementary to human UDP-GalNAc: Fuc alpha 1----2Gal alpha 1----3GalNAc transferase (histo-blood group A transferase) mRNA.
The Journal of biological chemistry 1990;265(2):1146-51.
1990: Henrik Clausen; T White; K Takio; K Titani; M Stroud; E Holmes; J Karkov; L Thim; S Hakomori
Isolation to homogeneity and partial characterization of a histo-blood group A defined Fuc alpha 1----2Gal alpha 1----3-N-acetylgalactosaminyltransferase from human lung tissue.
The Journal of biological chemistry 1990;265(2):1139-45.
1989: Hisao Nakasaki; T Mitomi; T Noto; K Ogoshi; H Hanaue; Y Tanaka; H Makuuchi; Henrik Clausen; S Hakomori
Mosaicism in the expression of tumor-associated carbohydrate antigens in human colonic and gastric cancers.
Cancer research 1989;49(13):3662-9.
1989: Torben F Orntoft; H Hvid; Henrik Clausen; S Hakomori; E Dabelsteen
Loss of blood group ABO-related antigen expression in urothelium from patients with chronic cystitis.
Laboratory investigation; a journal of technical methods and pathology 1989;60(2):305-10.
1989: T Kjeldsen; S Hakomori; G F Springer; P Desai; T Harris; Henrik Clausen
Coexpression of sialosyl-Tn (NeuAc alpha 2----6GalNAc alpha 1----O-Ser/Thr) and Tn (GalNAc alpha 1----O-Ser/Thr) blood group antigens on Tn erythrocytes.
Vox sanguinis 1989;57(1):81-7.
1989: Henrik Clausen; S Hakomori
ABH and related histo-blood group antigens; immunochemical differences in carrier isotypes and their distribution.
Vox sanguinis 1989;56(1):1-20.
1988: Ulla Mandel; Henrik Clausen; P Vedtofte; H Sørensen; Erik Dabelsteen
Sequential expression of carbohydrate antigens with precursor-product relation characterizes cellular maturation in stratified squamous epithelium.
Journal of oral pathology 1988;17(9-10):506-11.
1988: Erik Dabelsteen; Henrik Clausen; Palle Holmstrup; J Reibel
Premalignant and malignant oral lesions are associated with changes in the glycosylation pattern of carbohydrates related to ABH blood group antigens.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1988;96(9):813-9.
1988: Y Tsuji; Henrik Clausen; E Nudelman; T Kaizu; S Hakomori; S Isojima
Human sperm carbohydrate antigens defined by an antisperm human monoclonal antibody derived from an infertile woman bearing antisperm antibodies in her serum.
The Journal of experimental medicine 1988;168(1):343-56.
1988: Torben F Orntoft; H Wolf; Henrik Clausen; S Hakomori; E Dabelsteen
Blood group ABO-related antigens in fetal and normal adult bladder urothelium. Immunohistochemical study of type 2 chain structures with a panel of mouse monoclonal antibodies.
Laboratory investigation; a journal of technical methods and pathology 1988;58(5):576-83.
1988: T Kjeldsen; Henrik Clausen; S Hirohashi; T Ogawa; H Iijima; S Hakomori
Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.
Cancer research 1988;48(8):2214-20.
1988: Henrik Clausen; M Stroud; J Parker; G Springer; S Hakomori
Monoclonal antibodies directed to the blood group A associated structure, galactosyl-A: specificity and relation to the Thomsen-Friedenreich antigen.
Molecular immunology 1988;25(2):199-204.
1988: Erik Dabelsteen; N Graem; Henrik Clausen; S Hakomori
Structural variations of blood group A antigens in human normal colon and carcinomas.
Cancer research 1988;48(1):181-7.
1987: Henrik Clausen; Steven B Levery; E D Nudelman; M Stroud; M E Salyan; S Hakomori
Isolation and characterization of novel glycolipids with blood group A-related structures: galactosyl-A and sialosylgalactosyl-A.
The Journal of biological chemistry 1987;262(29):14228-34.