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Michael Cleary
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14
Warnke, Roger
11
Selleri, Licia
10
Hunger, Stephen
9
Ayton, Paul
8
Jacobs, Yakop
8
Smith, Kevin
8
So, Chi Wai
6
Somervaille, Tim
6
Schnabel, Catherine
6
Weissman, Irving
6
Carroll, Andrew
5
Firestein, Ron
5
DiMartino, Jorge
5
Kamel, Onsi
5
Link, Michael
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All Publications
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2009: Liedtke Michaela; Cleary Michael L
Therapeutic targeting of MLL.
Blood 2009;113(24):6061-8.
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2009: Somervaille Tim C P; Matheny Christina J; Spencer Gary J; Iwasaki Masayuki; Rinn John L; Witten Daniela M; Chang Howard Y; Shurtleff Sheila A; Downing James R; Cleary Michael L
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.
Cell stem cell 2009;4(2):129-40.
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2008: Chang Ching-Pin; Stankunas Kryn; Shang Ching; Kao Shih-Chu; Twu Karen Y; Cleary Michael L
Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract.
Development (Cambridge, England) 2008;135(21):3577-86.
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2008: Wang Zhong; Smith Kevin S; Murphy Mark; Piloto Obdulio; Somervaille Tim C P; Cleary Michael L
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.
Nature 2008;455(7217):1205-9.
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2008: Stankunas Kryn; Shang Ching; Twu Karen Y; Kao Shih-Chu; Jenkins Nancy A; Copeland Neal G; Sanyal Mrinmoy; Selleri Licia; Cleary Michael L; Chang Ching-Pin
Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart disease.
Circulation research 2008;103(7):702-9.
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2008: Yokoyama Akihiko; Cleary Michael L
Menin critically links MLL proteins with LEDGF on cancer-associated target genes.
Cancer cell 2008;14(1):36-46.
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2008: Ficara Francesca; Murphy Mark J; Lin Min; Cleary Michael L
Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.
Cell stem cell 2008;2(5):484-96.
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2008: Espinosa Inigo; Lee Cheng-Han; Kim Mi Kyung; Rouse Bich-Tien; Subramanian Subbaya; Montgomery Kelli; Varma Sushama; Corless Christopher L; Heinrich Michael C; Smith Kevin S; Wang Zhong; Rubin Brian; Nielsen Torsten O; Seitz Robert S; Ross Douglas T; West Robert B; Cleary Michael L; van de Rijn Matt
A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.
The American journal of surgical pathology 2008;32(2):210-8.
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2007: Wong Piu; Iwasaki Masayuki; Somervaille Tim C P; So Chi Wai Eric; Cleary Michael L
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
Genes & development 2007;21(21):2762-74.
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2007: Cheung Ngai; Chan Li Chong; Thompson Alex; Cleary Michael L; So Chi Wai Eric
Protein arginine-methyltransferase-dependent oncogenesis.
Nature cell biology 2007;9(10):1208-15.
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2007: Sanyal Mrinmoy; Tung James W; Karsunky Holger; Zeng Hong; Selleri Licia; Weissman Irving L; Herzenberg Leonore A; Cleary Michael L
B-cell development fails in the absence of the Pbx1 proto-oncogene.
Blood 2007;109(10):4191-9.
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2006: Somervaille Tim C P; Cleary Michael L
PU.1 and Junb: suppressing the formation of acute myeloid leukemia stem cells.
Cancer cell 2006;10(6):456-7.
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2006: Somervaille Tim C P; Cleary Michael L
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.
Cancer cell 2006;10(4):257-68.
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2005: Yokoyama Akihiko; Somervaille Tim C P; Smith Kevin S; Rozenblatt-Rosen Orit; Meyerson Matthew; Cleary Michael L
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Cell 2005;123(2):207-18.
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2005: Brendolan Andrea; Ferretti Elisabetta; Salsi Valentina; Moses Kelvin; Quaggin Susan; Blasi Francesco; Cleary Michael L; Selleri Licia
A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny.
Development (Cambridge, England) 2005;132(13):3113-26.
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2004: Manley Nancy R; Selleri Licia; Brendolan Andrea; Gordon Julie; Cleary Michael L
Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.
Developmental biology 2004;276(2):301-12.
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2004: Ayton Paul M; Chen Everett H; Cleary Michael L
Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.
Molecular and cellular biology 2004;24(23):10470-8.
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2004: Onimaru Hiroshi; Arata Akiko; Arata Satoru; Shirasawa Senji; Cleary Michael L
In vitro visualization of respiratory neuron activity in the newborn mouse ventral medulla.
Brain research. Developmental brain research 2004;153(2):275-9.
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2004: Rhee Joon Whan; Arata Akiko; Selleri Licia; Jacobs Yakop; Arata Satoru; Onimaru Hiroshi; Cleary Michael L
Pbx3 deficiency results in central hypoventilation.
The American journal of pathology 2004;165(4):1343-50.
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2004: So Chi Wai; Cleary Michael L
Dimerization: a versatile switch for oncogenesis.
Blood 2004;104(4):919-22.
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2004: Yokoyama Akihiko; Wang Zhong; Wysocka Joanna; Sanyal Mrinmoy; Aufiero Deborah J; Kitabayashi Issay; Herr Winship; Cleary Michael L
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.
Molecular and cellular biology 2004;24(13):5639-49.
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2004: Selleri Licia; DiMartino Jorge; van Deursen Jan; Brendolan Andrea; Sanyal Mrinmoy; Boon Elles; Capellini Terence; Smith Kevin S; Rhee Joon; Pöpperl Heike; Grosveld Gerard; Cleary Michael L
The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.
Molecular and cellular biology 2004;24(12):5324-31.
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2004: So Chi Wai; Karsunky Holger; Wong Piu; Weissman Irving L; Cleary Michael L
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.
Blood 2004;103(8):3192-9.
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2003: Cozzio Antonio; Passegué Emmanuelle; Ayton Paul M; Karsunky Holger; Cleary Michael L; Weissman Irving L
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.
Genes & development 2003;17(24):3029-35.
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2003: Schnabel Catherine A; Selleri Licia; Cleary Michael L
Pbx1 is essential for adrenal development and urogenital differentiation.
Genesis (New York, N.Y. : 2000) 2003;37(3):123-30.
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2003: Ayton Paul M; Cleary Michael L
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.
Genes & development 2003;17(18):2298-307.
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2003: Smith Kevin S; Chanda Sumit K; Lingbeek Merel; Ross Douglas T; Botstein David; van Lohuizen Maarten; Cleary Michael L
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1.
Molecular cell 2003;12(2):393-400.
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2003: So Chi Wai; Lin Min; Ayton Paul M; Chen Everett H; Cleary Michael L
Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias.
Cancer cell 2003;4(2):99-110.
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2003: Nagy Peter L; Cleary Michael L; Brown Patrick O; Lieb Jason D
Genomewide demarcation of RNA polymerase II transcription units revealed by physical fractionation of chromatin.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6364-9.
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2003: Kim Soo-A; Vacratsis Panayiotis O; Firestein Ron; Cleary Michael L; Dixon Jack E
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4492-7.
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2003: Deguchi Kenji; Ayton Paul M; Carapeti Melina; Kutok Jeffery L; Snyder Cynthia S; Williams Ifor R; Cross Nicholas C P; Glass Christopher K; Cleary Michael L; Gilliland D Gary
MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.
Cancer cell 2003;3(3):259-71.
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2003: So Chi Wai; Karsunky Holger; Passegué Emmanuelle; Cozzio Antonio; Weissman Irving L; Cleary Michael L
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice.
Cancer cell 2003;3(2):161-71.
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2003: Schnabel Catherine A; Godin Robert E; Cleary Michael L
Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney.
Developmental biology 2003;254(2):262-76.
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2003: So Chi Wai; Cleary Michael L
Common mechanism for oncogenic activation of MLL by forkhead family proteins.
Blood 2003;101(2):633-9.
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2002: Yokoyama Akihiko; Kitabayashi Issay; Ayton Paul M; Cleary Michael L; Ohki Misao
Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties.
Blood 2002;100(10):3710-8.
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2002: Smith Kevin S; Rhee Joon Whan; Cleary Michael L
Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.
Molecular and cellular biology 2002;22(21):7678-87.
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2002: So Chi Wai; Cleary Michael L
MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function.
Molecular and cellular biology 2002;22(18):6542-52.
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2002: Firestein Ron; Nagy Peter L; Daly Megan; Huie Phil; Conti Marco; Cleary Michael L
Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1.
The Journal of clinical investigation 2002;109(9):1165-72.
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2002: DiMartino Jorge F; Ayton Paul M; Chen Everett H; Naftzger Clarissa C; Young Bryan D; Cleary Michael L
The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.
Blood 2002;99(10):3780-5.
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2002: Kim Seung K; Selleri Licia; Lee Joon S; Zhang Andrew Y; Gu Xueying; Jacobs Yakop; Cleary Michael L
Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus.
Nature genetics 2002;30(4):430-5.
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2002: Nagy Peter L; Griesenbeck Joachim; Kornberg Roger D; Cleary Michael L
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):90-4.
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2001: Ayton P M; Cleary M L
Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins.
Oncogene 2001;20(40):5695-707.
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2001: Selleri L; Depew M J; Jacobs Y; Chanda S K; Tsang K Y; Cheah K S; Rubenstein J L; O'Gorman S; Cleary M L
Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.
Development (Cambridge, England) 2001;128(18):3543-57.
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2001: Firestein R; Cleary M L
Pseudo-phosphatase Sbf1 contains an N-terminal GEF homology domain that modulates its growth regulatory properties.
Journal of cell science 2001;114(Pt 16):2921-7.
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2001: DiMartino J F; Selleri L; Traver D; Firpo M T; Rhee J; Warnke R; O'Gorman S; Weissman I L; Cleary M L
The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver.
Blood 2001;98(3):618-26.
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2001: Schnabel C A; Selleri L; Jacobs Y; Warnke R; Cleary M L
Expression of Pbx1b during mammalian organogenesis.
Mechanisms of development 2001;100(1):131-5.
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2000: DiMartino J F; Miller T; Ayton P M; Landewe T; Hess J L; Cleary M L; Shilatifard A
A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL.
Blood 2000;96(12):3887-93.
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2000: Feldman B J; Hampton T; Cleary M L
A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice.
Blood 2000;96(5):1906-13.
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2000: Firestein R; Cui X; Huie P; Cleary M L
Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9.
Molecular and cellular biology 2000;20(13):4900-9.
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2000: Schnabel C A; Jacobs Y; Cleary M L
HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis.
Oncogene 2000;19(5):608-16.
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1999: Dimartino J F; Cleary M L
Mll rearrangements in haematological malignancies: lessons from clinical and biological studies.
British journal of haematology 1999;106(3):614-26.
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1999: Jacobs Y; Schnabel C A; Cleary M L
Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity.
Molecular and cellular biology 1999;19(7):5134-42.
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1999: Smith K S; Rhee J W; Naumovski L; Cleary M L
Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice.
Molecular and cellular biology 1999;19(6):4443-51.
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1999: Kasper L H; Brindle P K; Schnabel C A; Pritchard C E; Cleary M L; van Deursen J M
CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity.
Molecular and cellular biology 1999;19(1):764-76.
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1998: De Vivo I; Cui X; Domen J; Cleary M L
Growth stimulation of primary B cell precursors by the anti-phosphatase Sbf1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9471-6.
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1998: Cui X; De Vivo I; Slany R; Miyamoto A; Firestein R; Cleary M L
Association of SET domain and myotubularin-related proteins modulates growth control.
Nature genetics 1998;18(4):331-7.
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1998: Slany R K; Lavau C; Cleary M L
The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.
Molecular and cellular biology 1998;18(1):122-9.
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1997: Feldman B J; Reid T R; Cleary M L
Pim1 cooperates with E2a-Pbx1 to facilitate the progression of thymic lymphomas in transgenic mice.
Oncogene 1997;15(22):2735-42.
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1997: LeBrun D P; Matthews B P; Feldman B J; Cleary M L
The chimeric oncoproteins E2A-PBX1 and E2A-HLF are concentrated within spherical nuclear domains.
Oncogene 1997;15(17):2059-67.
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1997: Chang C P; Jacobs Y; Nakamura T; Jenkins N A; Copeland N G; Cleary M L
Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins.
Molecular and cellular biology 1997;17(10):5679-87.
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1997: Lavau C; Szilvassy S J; Slany R; Cleary M L
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.
The EMBO journal 1997;16(14):4226-37.
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1997: Smith K S; Jacobs Y; Chang C P; Cleary M L
Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.
Oncogene 1997;14(24):2917-26.
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1997: Butler L H; Slany R; Cui X; Cleary M L; Mason D Y
The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures.
Blood 1997;89(9):3361-70.
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1997: Chang C P; de Vivo I; Cleary M L
The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
Molecular and cellular biology 1997;17(1):81-8.
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1997: Waring P M; Cleary M L
Disruption of a homolog of trithorax by 11q23 translocations: leukemogenic and transcriptional implications.
Current topics in microbiology and immunology 1997;220():1-23.
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1996: Naumovski L; Cleary M L
The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M.
Molecular and cellular biology 1996;16(7):3884-92.
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1996: Soslow R A; Davis R E; Warnke R A; Cleary M L; Kamel O W
True histiocytic lymphoma following therapy for lymphoblastic neoplasms.
Blood 1996;87(12):5207-12.
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1996: Hunger S P; Li S; Fall M Z; Naumovski L; Cleary M L
The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties.
Blood 1996;87(11):4607-17.
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1996: Miyamoto A; Cui X; Naumovski L; Cleary M L
Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells.
Molecular and cellular biology 1996;16(5):2394-401.
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1996: Chang C P; Brocchieri L; Shen W F; Largman C; Cleary M L
Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.
Molecular and cellular biology 1996;16(4):1734-45.
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1996: Shen W F; Chang C P; Rozenfeld S; Sauvageau G; Humphries R K; Lu M; Lawrence H J; Cleary M L; Largman C
Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA.
Nucleic acids research 1996;24(5):898-906.
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1995: Kamel O W; Gocke C D; Kell D L; Cleary M L; Warnke R A
True histiocytic lymphoma: a study of 12 cases based on current definition.
Leukemia & lymphoma 1995;18(1-2):81-6.
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1995: Chang C P; Shen W F; Rozenfeld S; Lawrence H J; Largman C; Cleary M L
Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.
Genes & development 1995;9(6):663-74.
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1994: Monica K; LeBrun D P; Dedera D A; Brown R; Cleary M L
Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
Molecular and cellular biology 1994;14(12):8304-14.
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1994: Gelb A B; van de Rijn M; Regula D P; Cornbleet J P; Kamel O W; Horoupian D S; Cleary M L; Warnke R A
Epstein-Barr virus-associated natural killer-large granular lymphocyte leukemia.
Human pathology 1994;25(9):953-60.
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1994: Rubnitz J E; Morrissey J; Savage P A; Cleary M L
ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells.
Blood 1994;84(6):1747-52.
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1994: Hunger S P; Brown R; Cleary M L
DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF.
Molecular and cellular biology 1994;14(9):5986-96.
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1994: Rubnitz J E; Link M P; Shuster J J; Carroll A J; Hakami N; Frankel L S; Pullen D J; Cleary M L
Frequency and prognostic significance of HRX rearrangements in infant acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Blood 1994;84(2):570-3.
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1994: LeBrun D P; Cleary M L
Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
Oncogene 1994;9(6):1641-7.
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1994: Hunger S P; Devaraj P E; Foroni L; Secker-Walker L M; Cleary M L
Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL.
Blood 1994;83(10):2970-7.
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1994: LeBrun D P; Ngan B Y; Weiss L M; Huie P; Warnke R A; Cleary M L
The bcl-2 oncogene in Hodgkin's disease arising in the setting of follicular non-Hodgkin's lymphoma.
Blood 1994;83(1):223-30.
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1993: Hunger S P; Cleary M L
Chimaeric oncoproteins resulting from chromosomal translocations in acute lymphoblastic leukaemia.
Seminars in cancer biology 1993;4(6):387-99.
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1993: Dedera D A; Waller E K; LeBrun D P; Sen-Majumdar A; Stevens M E; Barsh G S; Cleary M L
Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice.
Cell 1993;74(5):833-43.
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1993: Borowitz M J; Hunger S P; Carroll A J; Shuster J J; Pullen D J; Steuber C P; Cleary M L
Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study.
Blood 1993;82(4):1086-91.
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1993: Hunger S P; Tkachuk D C; Amylon M D; Link M P; Carroll A J; Welborn J L; Willman C L; Cleary M L
HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities.
Blood 1993;81(12):3197-203.
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1993: Morrissey J; Tkachuk D C; Milatovich A; Francke U; Link M; Cleary M L
A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias.
Blood 1993;81(5):1124-31.
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1993: LeBrun D P; Warnke R A; Cleary M L
Expression of bcl-2 in fetal tissues suggests a role in morphogenesis.
The American journal of pathology 1993;142(3):743-53.
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1993: Chleq-Deschamps C M; LeBrun D P; Huie P; Besnier D P; Warnke R A; Sibley R K; Cleary M L
Topographical dissociation of BCL-2 messenger RNA and protein expression in human lymphoid tissues.
Blood 1993;81(2):293-8.
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1992: Tkachuk D C; Kohler S; Cleary M L
Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias.
Cell 1992;71(4):691-700.
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1992: Hunger S P; Ohyashiki K; Toyama K; Cleary M L
Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.
Genes & development 1992;6(9):1608-20.
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1992: LeBrun D P; Kamel O W; Cleary M L; Dorfman R F; Warnke R A
Follicular lymphomas of the gastrointestinal tract. Pathologic features in 31 cases and bcl-2 oncogenic protein expression.
The American journal of pathology 1992;140(6):1327-35.
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1992: Cleary M L
Transcription factors in human leukaemias.
Cancer surveys 1992;15():89-104.
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1991: Monica K; Galili N; Nourse J; Saltman D; Cleary M L
PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.
Molecular and cellular biology 1991;11(12):6149-57.
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1991: Waller E K; Kamel O W; Cleary M L; Majumdar A S; Schick M R; Lieberman M; Weissman I L
Growth of primary T-cell non-Hodgkin's lymphomata in SCID-hu mice: requirement for a human lymphoid microenvironment.
Blood 1991;78(10):2650-65.
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1991: Zelenetz A D; Chu G; Galili N; Bangs C D; Horning S J; Donlon T A; Cleary M L; Levy R
Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis.
Blood 1991;78(6):1552-60.
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1991: Cleary M L
Oncogenic conversion of transcription factors by chromosomal translocations.
Cell 1991;66(4):619-22.
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1991: Kuo S S; Mellentin J D; Copeland N G; Gilbert D J; Jenkins N A; Cleary M L
Structure, chromosome mapping, and expression of the mouse Lyl-1 gene.
Oncogene 1991;6(6):961-8.
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1991: Davis R E; Warnke R A; Dorfman R F; Cleary M L
Utility of molecular genetic analysis for the diagnosis of neoplasia in morphologically and immunophenotypically equivocal hematolymphoid lesions.
Cancer 1991;67(11):2890-9.
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1991: Ngan B Y; Warnke R A; Wilson M; Takagi K; Cleary M L; Dorfman R F
Monocytoid B-cell lymphoma: a study of 36 cases.
Human pathology 1991;22(5):409-21.
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1991: Hunger S P; Galili N; Carroll A J; Crist W M; Link M P; Cleary M L
The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias.
Blood 1991;77(4):687-93.
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1991: Suryanarayan K; Hunger S P; Kohler S; Carroll A J; Crist W; Link M P; Cleary M L
Consistent involvement of the bcr gene by 9;22 breakpoints in pediatric acute leukemias.
Blood 1991;77(2):324-30.
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1991: Cleary M L
The bcl-2 gene and protein in malignant lymphomas.
Bulletin du cancer 1991;78(2):187-93.
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1990: Kiem H P; Nourse J; Saltman D L; Blume K G; Cleary M L
Concurrent activation of c-myc and inactivation of bcl-2 by chromosomal translocation in a lymphoblastic lymphoma cell line.
Oncogene 1990;5(12):1815-9.
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1990: Saltman D L; Mellentin J D; Smith S D; Cleary M L
Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization.
Genes, chromosomes & cancer 1990;2(4):259-65.
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1990: Mellentin J D; Nourse J; Hunger S P; Smith S D; Cleary M L
Molecular analysis of the t(1;19) breakpoint cluster region in pre-B cell acute lymphoblastic leukemias.
Genes, chromosomes & cancer 1990;2(3):239-47.
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1990: Kohler S; Galili N; Sklar J L; Donlon T A; Blume K G; Cleary M L
Expression of bcr-abl fusion transcripts following bone marrow transplantation for Philadelphia chromosome-positive leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(8):541-7.
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1990: Monica K; Chen-Levy Z; Cleary M L
Small G proteins are expressed ubiquitously in lymphoid cells and do not correspond to Bcl-2.
Nature 1990;346(6280):189-91.
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1990: Chen-Levy Z; Cleary M L
Membrane topology of the Bcl-2 proto-oncogenic protein demonstrated in vitro.
The Journal of biological chemistry 1990;265(9):4929-33.
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1990: Nourse J; Mellentin J D; Galili N; Wilkinson J; Stanbridge E; Smith S D; Cleary M L
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor.
Cell 1990;60(4):535-45.
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1989: Ngan B; Warnke A; Cleary M L
Variability of immunoglobulin expression in follicular lymphoma. An immunohistologic and molecular genetic study.
The American journal of pathology 1989;135(6):1139-44.
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1989: Mellentin J D; Murre C; Donlon T A; McCaw P S; Smith S D; Carroll A J; McDonald M E; Baltimore D; Cleary M L
The gene for enhancer binding proteins E12/E47 lies at the t(1;19) breakpoint in acute leukemias.
Science (New York, N.Y.) 1989;246(4928):379-82.
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1989: Wood G S; Ngan B Y; Tung R; Hoffman T E; Abel E A; Hoppe R T; Warnke R A; Cleary M L; Sklar J
Clonal rearrangements of immunoglobulin genes and progression to B cell lymphoma in cutaneous lymphoid hyperplasia.
The American journal of pathology 1989;135(1):13-9.
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1989: Mellentin J D; Smith S D; Cleary M L
lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif.
Cell 1989;58(1):77-83.
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1989: Ngan B Y; Nourse J; Cleary M L
Detection of chromosomal translocation t(14;18) within the minor cluster region of bcl-2 by polymerase chain reaction and direct genomic sequencing of the enzymatically amplified DNA in follicular lymphomas.
Blood 1989;73(7):1759-62.
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1989: Chen-Levy Z; Nourse J; Cleary M L
The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation.
Molecular and cellular biology 1989;9(2):701-10.
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1988: Cleary M L; Nalesnik M A; Shearer W T; Sklar J
Clonal analysis of transplant-associated lymphoproliferations based on the structure of the genomic termini of the Epstein-Barr virus.
Blood 1988;72(1):349-52.
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1988: Ngan B Y; Chen-Levy Z; Weiss L M; Warnke R A; Cleary M L
Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation.
The New England journal of medicine 1988;318(25):1638-44.
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1988: LeBoit P E; Abel E A; Cleary M L; Hoppe R T; Williams M L; Wood G S; Parslow T G
Clonal rearrangement of the T cell receptor beta gene in the circulating lymphocytes of erythrodermic follicular mucinosis.
Blood 1988;71(5):1329-33.
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1988: Carroll W L; Link M P; Cleary M L; Bologna S; Carswell C; Amylon M D; Smith S D; Levy R
Idiotype as a tumor-specific marker in childhood B cell acute lymphoblastic leukemia.
Blood 1988;71(4):1068-73.
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1988: Cleary M L; Mellentin J D; Spies J; Smith S D
Chromosomal translocation involving the beta T cell receptor gene in acute leukemia.
The Journal of experimental medicine 1988;167(2):682-7.
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1988: Cleary M L; Galili N; Trela M; Levy R; Sklar J
Single cell origin of bigenotypic and biphenotypic B cell proliferations in human follicular lymphomas.
The Journal of experimental medicine 1988;167(2):582-97.
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1987: Weiss L M; Warnke R A; Sklar J; Cleary M L
Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas.
The New England journal of medicine 1987;317(19):1185-9.
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1987: Galili N; Cleary M L; Sklar J
Human follicular lymphomas: identification of a second t(14;18) breakpoint cluster region.
Haematology and blood transfusion 1987;31():167-71.
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