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Roger Clegg

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Roger A Clegg; Annalise V Bicknell; Laura C Bowen; Mark C Prescott; Huw H Rees; Mohammad Tabish; Michael J Fisher
Characterisation of the N'1 isoform of the cyclic AMP-dependent protein kinase (PK-A) catalytic subunit in the nematode, Caenorhabditis elegans.
Carl Holt; Esben S Sørensen; Roger A Clegg
Role of calcium phosphate nanoclusters in the control of calcification.
Gordon J Allan; Elizabeth Tonner; Malgorzata Szymanowska; John H Shand; Sharon M Kelly; Kirsten Phillips; Roger A Clegg; Iain F Gow; James Beattie; David J Flint
Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action.

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All Publications

2012: Roger A Clegg; Annalise V Bicknell; Laura C Bowen; Mark C Prescott; Huw H Rees; Mohammad Tabish; Michael J Fisher
Characterisation of the N'1 isoform of the cyclic AMP-dependent protein kinase (PK-A) catalytic subunit in the nematode, Caenorhabditis elegans.
Archives of biochemistry and biophysics 2012;519(1):38-45.
2009: Carl Holt; Esben S Sørensen; Roger A Clegg
Role of calcium phosphate nanoclusters in the control of calcification.
The FEBS journal 2009;276(8):2308-23.
2006: Gordon J Allan; Elizabeth Tonner; Malgorzata Szymanowska; John H Shand; Sharon M Kelly; Kirsten Phillips; Roger A Clegg; Iain F Gow; James Beattie; David J Flint
Cumulative mutagenesis of the basic residues in the 201-218 region of insulin-like growth factor (IGF)-binding protein-5 results in progressive loss of both IGF-I binding and inhibition of IGF-I biological action.
Endocrinology 2006;147(1):338-49.
2003: Maureen T Travers; Amanda J Vallance; Roger A Clegg; Ross Thomson; Nigel T Price; Michael Barber
Characterisation of an N-terminal variant of acetyl-CoA carboxylase-alpha: expression in human tissues and evolutionary aspects.
Biochimica et biophysica acta 2003;1634(3):97-106.
2000: Roger A Clegg; R A Gardner; R N Sumathipala; Françoise Lavialle; Raphaël Boisgard; Michèle Ollivier-Bousquet
Targeting of PKA in mammary epithelial cells. Mechanisms and functional consequences.
Advances in experimental medicine and biology 2000;480():99-105.
1999: Roger A Clegg; P C Gordge; W R Miller
Expression of enzymes of covalent protein modification during regulated and dysregulated proliferation of mammary epithelial cells: PKA, PKC and NMT.
Advances in enzyme regulation 1999;39():175-203.
1998: R N Sumathipala; Maureen T Travers; P Thomas; M R Munday; Roger A Clegg
Expression of FAT, the putative fatty acid translocator protein, is developmentally regulated in rat mammary tissue.
Biochemical Society transactions 1998;26(3):S232.
1998: Roger A Clegg; R A Gardner; Françoise Lavialle; Raphaël Boisgard; Michèle Ollivier-Bousquet
Casein secretion in mammary tissue: tonic regulation of basal secretion by protein kinase A.
Molecular and cellular endocrinology 1998;141(1-2):163-77.
1997: Roger A Clegg
Expression of N-myristoyl transferase is developmentally regulated in mammary epithelial cells.
Biochemical Society transactions 1997;25(4):S680.
1997: Roger A Clegg; James Beattie
Cellular uptake and metabolism of myristoylated N-terminal peptides of PKA C-subunit.
Biochemical Society transactions 1997;25(4):S679.
1997: Roger A Clegg
Post-translational protein N-myristoylation in mammary epithelial cells.
Biochemical Society transactions 1997;25(4):S675.
1997: Roger A Clegg
AKAP expression in rat mammary gland.
Biochemical Society transactions 1997;25(4):S634.
1997: Michael Barber; Roger A Clegg; Maureen T Travers; Richard G Vernon
Lipid metabolism in the lactating mammary gland.
Biochimica et biophysica acta 1997;1347(2-3):101-26.
1996: P C Gordge; M J Hulme; Roger A Clegg; William R Miller
Elevation of protein kinase A and protein kinase C activities in malignant as compared with normal human breast tissue.
European journal of cancer (Oxford, England : 1990) 1996;32A(12):2120-6.
1996: P C Gordge; S E Withers; K Connor; W R Miller; Roger A Clegg
Protein kinase C does not acutely modulate protein kinase A activity in mammary gland acini prepared from mid-pregnant and mid-lactating rats.
Biochemical Society transactions 1996;24(3):338S.
1996: J Simpson; M S Johnson; Roger A Clegg; R Mitchell
Separation of H7-resistant protein kinase C isoforms from gonadotroph-derived alpha T3-1 cells.
Biochemical and biophysical research communications 1996;218(3):720-5.
1996: DT Calvert; Roger A Clegg
Responses of glucose metabolism to insulin in perfused mammary tissue of lactating rats: influence of dietary history and recent insulin experience.
Experimental physiology 1996;81(1):131-40.
1995: R A Gardner; Maureen T Travers; Michael Barber; W R Miller; Roger A Clegg
Expression of PK-A catalytic and regulatory subunits in lactating rat mammary tissue: effects of litter removal.
Biochemical Society transactions 1995;23(3):452S.
1995: P C Gordge; Roger A Clegg; W R Miller
Ca(2+)-dependent and Ca(2+)-independent protein kinase C activity in human breast biopsies.
Biochemical Society transactions 1995;23(3):449S.
1995: M S Johnson; J Simpson; D J MacEwan; A Ison; Roger A Clegg; K Connor; R Mitchell
Phorbol ester and diacylglycerol activation of native protein kinase C species from various tissues.
Molecular and cellular biochemistry 1995;146(2):127-37.
1995: M S Johnson; J Simpson; Roger A Clegg; R Mitchell
The properties of protein kinase C zeta purified from alpha T3-1 cells using hydroxyapatite chromatography.
Biochemical Society transactions 1995;23(1):147S.
1995: A J Ison; J Simpson; Eve M Lutz; Roger A Clegg; K Connor; R Mitchell
A novel high molecular weight form of protein kinase C in anterior pituitary.
Biochemical Society transactions 1995;23(1):146S.
1994: R A Gardner; Maureen T Travers; Michael Barber; W R Miller; Roger A Clegg
Cyclic AMP-dependent protein kinase in rat mammary tissue: expression of catalytic and regulatory subunits throughout pregnancy and lactation.
The Biochemical journal 1994;301 ( Pt 3)():807-12.
1994: R A Gardner; Roger A Clegg
Immunoinhibition of protein kinase activity of PK-A catalytic subunit.
Biochemical Society transactions 1994;22(2):211S.
1993: DT Calvert; K Connor; Roger A Clegg
Isoprenaline-induced lipolysis in perfused mammary tissue.
Biochemical Society transactions 1993;21(4):456S.
1993: J Beattie; Roger A Clegg
Surface-accessibility of the myristoylated N-terminus of PK-A catalytic subunit probed with anti-peptide antibodies.
Biochemical Society transactions 1993;21(4):399S.
1993: R A Gardner; Maureen T Travers; Michael Barber; W R Miller; Roger A Clegg
Expression of PK-A catalytic subunit in mammary tissue during pregnancy and lactation.
Biochemical Society transactions 1993;21(4):398S.
1993: A J Ison; M S Johnson; D J MacEwan; J Simpson; Roger A Clegg; K Connor; R Mitchell
Biochemical characterisation of an apparently novel isoform of protein kinase C in pituitary.
Biochemical Society transactions 1993;21(4):386S.
1993: A J Ison; D J MacEwan; M S Johnson; Roger A Clegg; K Connor; R Mitchell
Evidence for a distinct H7-resistant form of protein kinase C in rat anterior pituitary gland.
FEBS letters 1993;329(1-2):199-204.
1993: D J MacEwan; R Mitchell; M S Johnson; Fiona Thomson; Eve M Lutz; Roger A Clegg; K Connor
Evidence that protein kinase C alpha has reduced affinity towards 1,2-dioctanoyl-sn-glycerol: the effects of lipid activators on phorbol ester binding and kinase activity.
European journal of pharmacology 1993;246(1):9-18.
1993: K Connor; Roger A Clegg
Isoenzymes of protein kinase C in rat mammary tissue: changes in properties and relative amounts during pregnancy and lactation.
The Biochemical journal 1993;291 ( Pt 3)():817-24.
1992: Roger A Clegg; K Connor
N-myristoylation of the catalytic subunit of PK-A: does this covalent modification specify receptor recognition?
Biochemical Society transactions 1992;20(4):386S.
1991: Roger A Clegg; D W West
Calcium-translocation into mammary Golgi vesicles: molecular identity of Ca(2+) -ATPases.
Biochemical Society transactions 1991;19(2):194S.
1991: P W Watt; E Finley; S Cork; Roger A Clegg; Richard G Vernon
Chronic control of the beta- and alpha 2-adrenergic systems of sheep adipose tissue by growth hormone and insulin.
The Biochemical journal 1991;273(Pt 1)():39-42.
1991: Roger A Clegg; K Connor
Cyclic AMP-dependent protein kinase in mammary epithelial cells; activity and subcellular distribution are acutely modulated by isoprenaline.
Cellular signalling 1991;3(3):201-8.
1990: A M Jamieson; M Paschke; Roger A Clegg
Mammary tissue lipocortins of the lactating rat.
Biochemical Society transactions 1990;18(6):1116-7.
1990: Roger A Clegg; K A Ottey
Cyclic AMP-dependent protein kinase in mammary tissue of the lactating rat. Activity ratio and responsiveness of the target enzymes acetyl-CoA carboxylase and glycogen phosphorylase to beta-adrenergic stimulation.
The Biochemical journal 1990;265(3):769-75.
1988: Roger A Clegg; DT Calvert
An 'in situ' perfusion system suitable for investigating mammary-tissue metabolism in the lactating rat. Hormonal regulation of acetyl-CoA carboxylase.
The Biochemical journal 1988;249(3):771-7.