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Allen Clermont

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Jia Liu; Ben-Bo Gao; Allen Clermont; Edward P Feener
Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein.
Christian Rask-Madsen; Mark Rekhter; Oluwatobi Yerokun; Erica Buonomo; Allen Clermont; Qian Li; Kyoungmin Park; George L King
Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice.
Allen Clermont; Tamie J Chilcote; Takeshi Kita; Jia Liu; Priscilla Riva; Sukanto Sinha; Edward P Feener
Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats.

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All Publications

2013: Jia Liu; Ben-Bo Gao; Allen Clermont; Edward P Feener
Intraocular hemorrhage causes retinal vascular dysfunction via plasma kallikrein.
Investigative ophthalmology & visual science 2013;54(2):1086-94.
2012: Christian Rask-Madsen; Mark Rekhter; Oluwatobi Yerokun; Erica Buonomo; Allen Clermont; Qian Li; Kyoungmin Park; George L King
Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(5):1124-31.
2011: Allen Clermont; Tamie J Chilcote; Takeshi Kita; Jia Liu; Priscilla Riva; Sukanto Sinha; Edward P Feener
Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats.
Diabetes 2011;60(5):1590-8.
2011: Jia Liu; Ben-Bo Gao; Allen Clermont; Price Blair; Tamie J Chilcote; Sukanto Sinha; Robert Flaumenhaft; Edward P Feener
Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein.
Nature medicine 2011;17(2):206-10.
2010: Christian Rask-Madsen; Qian Li; Bryn Freund; Danielle Feather; Roman Abramov; I-Hsien Wu; Kai Chen; Junko Yamamoto-Hiraoka; Jan Goldenbogen; Konstantinos B Sotiropoulos; Allen Clermont; Pedro Geraldes; Claudia Dall'Osso; Amy J Wagers; Paul L Huang; Mark Rekhter; Rosario Scalia; C Ronald Kahn; George L King
Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice.
Cell metabolism 2010;11(5):379-89.
2009: Ben-Bo Gao; Joanna A Phipps; Dahlia Bursell; Allen Clermont; Edward P Feener
Angiotensin AT1 receptor antagonism ameliorates murine retinal proteome changes induced by diabetes.
Journal of proteome research 2009;8(12):5541-9.
2009: Pedro Geraldes; Junko Hiraoka-Yamamoto; Motonobu Matsumoto; Allen Clermont; Michael Leitges; Andre Marette; Lloyd P Aiello; Timothy S Kern; George L King
Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy.
Nature medicine 2009;15(11):1298-306.
2009: Joanna A Phipps; Allen Clermont; Sukanto Sinha; Tamie J Chilcote; Sven-Erik Bursell; Edward P Feener
Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability.
Hypertension 2009;53(2):175-81.
2007: Pedro Geraldes; Michiko Yamagata; Susan L Rook; Yukio Sassa; Ronald Ma; Allen Clermont; Benbo Gao; Lloyd Paul Aiello; Edward P Feener; George L King
Glypican 4, a membrane binding protein for bactericidal/permeability-increasing protein signaling pathways in retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2007;48(12):5750-5.
2007: Ben-Bo Gao; Allen Clermont; Susan L Rook; Stephanie J Fonda; Vivek J Srinivasan; Maciej Wojtkowski; Mohammad Kamal; Robert L Avery; Paul G Arrigg; Sven-Erik Bursell; Lloyd Paul Aiello; Edward P Feener
Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation.
Nature medicine 2007;13(2):181-8.
2007: Allen Clermont; Sven-Erik Bursell
Retinal blood flow in diabetes.
Microcirculation (New York, N.Y. : 1994) 2007;14(1):49-61.
2006: Vivek J Srinivasan; Tony H Ko; Maciej Wojtkowski; Mariana Carvalho; Allen Clermont; Sven-Erik Bursell; Qin Hui Song; Janis Lem; Jay S Duker; Joel Schuman; Mohammad Kamal
Noninvasive volumetric imaging and morphometry of the rodent retina with high-speed, ultrahigh-resolution optical coherence tomography.
Investigative ophthalmology & visual science 2006;47(12):5522-8.
2006: Yuzuru Ohshiro; Ronald Ma; Yutaka Yasuda; Junko Hiraoka-Yamamoto; Allen Clermont; Keiji Isshiki; Kunimasa Yagi; Emi Arikawa; Timothy S Kern; George L King
Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.
Diabetes 2006;55(11):3112-20.
2006: Michiko Yamagata; Susan L Rook; Yukio Sassa; Ronald Ma; Pedro Geraldes; Lucy Goddard; Allen Clermont; Benbo Gao; Haytham Salti; Robert Gundel; Mark White; Edward P Feener; Lloyd Paul Aiello; George L King
Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(12):2058-67.
2006: Allen Clermont; Mark Cahill; Haytham Salti; Susan L Rook; Christian Rask-Madsen; Lucy Goddard; Jun S Wong; Dahlia Bursell; Sven-Erik Bursell; Lloyd Paul Aiello
Hepatocyte growth factor induces retinal vascular permeability via MAP-kinase and PI-3 kinase without altering retinal hemodynamics.
Investigative ophthalmology & visual science 2006;47(6):2701-8.
2006: Konstantinos B Sotiropoulos; Allen Clermont; Yutaka Yasuda; Christian Rask-Madsen; Motonobu Mastumoto; Junichi Takahashi; Kim Della Vecchia; Tatsuya Kondo; Lloyd Paul Aiello; George L King
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1203-5.
2006: Allen Clermont; Sven-Erik Bursell; Edward P Feener
Role of the angiotensin II type 1 receptor in the pathogenesis of diabetic retinopathy: effects of blood pressure control and beyond.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 2006;24(1):S73-80.
2006: Keiko Naruse; Christian Rask-Madsen; Noriko Takahara; Sung-woo Ha; Kiyoshi Suzuma; Kerrie J Way; Judith R C Jacobs; Allen Clermont; Kohjiro Ueki; Yuzuru Ohshiro; Junqing Zhang; Allison B Goldfine; George L King
Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance.
Diabetes 2006;55(3):691-8.
2006: Lloyd Paul Aiello; Allen Clermont; Vipin Arora; Matthew D Davis; Matthew J Sheetz; Sven-Erik Bursell
Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients.
Investigative ophthalmology & visual science 2006;47(1):86-92.
2005: Zhiheng He; Kerrie J Way; Emi Arikawa; Eva Chou; Darren M Opland; Allen Clermont; Keiji Isshiki; Ronald Ma; Joshua A Scott; Frederick Schoen; Edward P Feener; George L King
Differential regulation of angiotensin II-induced expression of connective tissue growth factor by protein kinase C isoforms in the myocardium.
The Journal of biological chemistry 2005;280(16):15719-26.
2004: N Horio; Allen Clermont; Atsuko Abiko; Toru Abiko; B D Shoelson; Sven-Erik Bursell; Edward P Feener
Angiotensin AT(1) receptor antagonism normalizes retinal blood flow and acetylcholine-induced vasodilatation in normotensive diabetic rats.
Diabetologia 2004;47(1):113-23.
2003: Toru Abiko; Atsuko Abiko; Allen Clermont; Brett Shoelson; Naoichi Horio; Junichi Takahashi; Anthony P Adamis; George L King; Sven-Erik Bursell
Characterization of retinal leukostasis and hemodynamics in insulin resistance and diabetes: role of oxidants and protein kinase-C activation.
Diabetes 2003;52(3):829-37.
2002: Eva Chou; Izumi Suzuma; Kerrie J Way; Darren M Opland; Allen Clermont; Keiko Naruse; Kiyoshi Suzuma; Nancy L Bowling; chris vlahos; Lloyd Paul Aiello; George L King
Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic States: a possible explanation for impaired collateral formation in cardiac tissue.
Circulation 2002;105(3):373-9.
2001: M Meier; George L King; Allen Clermont; A Perez; M Hayashi; Edward P Feener
Angiotensin AT(1) receptor stimulates heat shock protein 27 phosphorylation in vitro and in vivo.
Hypertension 2001;38(6):1260-5.
2001: Sven-Erik Bursell; Jerry D Cavallerano; Anthony A Cavallerano; Allen Clermont; D Birkmire-Peters; Lloyd Paul Aiello; Lloyd M Aiello
Stereo nonmydriatic digital-video color retinal imaging compared with Early Treatment Diabetic Retinopathy Study seven standard field 35-mm stereo color photos for determining level of diabetic retinopathy.
Ophthalmology 2001;108(3):572-85.
2001: Izumi Suzuma; Y Hata; Allen Clermont; F Pokras; Susan L Rook; Kiyoshi Suzuma; Edward P Feener; Lloyd Paul Aiello
Cyclic stretch and hypertension induce retinal expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2: potential mechanisms for exacerbation of diabetic retinopathy by hypertension.
Diabetes 2001;50(2):444-54.
2000: D Feng; Sven-Erik Bursell; Allen Clermont; Izabella Lipinska; Lloyd Paul Aiello; L Laffel; G L King; Geoffrey H Tofler
von Willebrand factor and retinal circulation in early-stage retinopathy of type 1 diabetes.
Diabetes care 2000;23(11):1694-8.
2000: F Mori; George L King; Allen Clermont; D K Bursell; Sven-Erik Bursell
Endothelin-3 regulation of retinal hemodynamics in nondiabetic and diabetic rats.
Investigative ophthalmology & visual science 2000;41(12):3955-62.
2000: H C Chen; JL Bouchie; A S Perez; Allen Clermont; S Izumo; J Hampe; Edward P Feener
Role of the angiotensin AT(1) receptor in rat aortic and cardiac PAI-1 gene expression.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2297-302.
2000: Y Hata; Allen Clermont; T Yamauchi; E A Pierce; Izumi Suzuma; H Kagokawa; H Yoshikawa; GS Robinson; T Ishibashi; T Hashimoto; Fumio Umeda; Sven-Erik Bursell; Lloyd Paul Aiello
Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor.
The Journal of clinical investigation 2000;106(4):541-50.
1999: K Miyamoto; S Khosrof; Sven-Erik Bursell; Richard M Rohan; T Murata; Allen Clermont; Lloyd Paul Aiello; Y Ogura; Anthony P Adamis
Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10836-41.
1999: Sven-Erik Bursell; Allen Clermont; Lloyd Paul Aiello; Lloyd M Aiello; D K Schlossman; Edward P Feener; L Laffel; G L King
High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes.
Diabetes care 1999;22(8):1245-51.
1998: S Higashi; Allen Clermont; V Dhir; Sven-Erik Bursell
Reversibility of retinal flow abnormalities is disease-duration dependent in diabetic rats.
Diabetes 1998;47(4):653-9.
1997: Sven-Erik Bursell; C Takagi; Allen Clermont; H Takagi; F Mori; H Ishii; G L King
Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.
Investigative ophthalmology & visual science 1997;38(13):2711-20.
1997: Allen Clermont; Lloyd Paul Aiello; F Mori; Lloyd M Aiello; Sven-Erik Bursell
Vascular endothelial growth factor and severity of nonproliferative diabetic retinopathy mediate retinal hemodynamics in vivo: a potential role for vascular endothelial growth factor in the progression of nonproliferative diabetic retinopathy.
American journal of ophthalmology 1997;124(4):433-46.
1997: Lloyd Paul Aiello; Sven-Erik Bursell; Allen Clermont; Elia J Duh; H Ishii; C Takagi; F Mori; T A Ciulla; K Ways; M Jirousek; L E Smith; George L King
Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor.
Diabetes 1997;46(9):1473-80.
1996: C Takagi; Sven-Erik Bursell; Y W Lin; H Takagi; Elia J Duh; Z Jiang; Allen Clermont; George L King
Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1.
Investigative ophthalmology & visual science 1996;37(12):2504-18.
1996: C Takagi; George L King; H Takagi; Y W Lin; Allen Clermont; Sven-Erik Bursell
Endothelin-1 action via endothelin receptors is a primary mechanism modulating retinal circulatory response to hyperoxia.
Investigative ophthalmology & visual science 1996;37(10):2099-109.
1996: H Ishii; M R Jirousek; D Koya; C Takagi; P Xia; Allen Clermont; Sven-Erik Bursell; Timothy S Kern; L M Ballas; W F Heath; L E Stramm; Edward P Feener; George L King
Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor.
Science (New York, N.Y.) 1996;272(5262):728-31.
1996: Sven-Erik Bursell; Allen Clermont; BT Kinsley; DC Simonson; Lloyd M Aiello; H A Wolpert
Retinal blood flow changes in patients with insulin-dependent diabetes mellitus and no diabetic retinopathy.
Investigative ophthalmology & visual science 1996;37(5):886-97.
1995: C Takagi; George L King; Allen Clermont; D R Cummins; H Takagi; Sven-Erik Bursell
Reversal of abnormal retinal hemodynamics in diabetic rats by acarbose, an alpha-glucosidase inhibitor.
Current eye research 1995;14(9):741-9.
1995: M Kunisaki; Sven-Erik Bursell; Allen Clermont; H Ishii; L M Ballas; M R Jirousek; Fumio Umeda; H Nawata; George L King
Vitamin E prevents diabetes-induced abnormal retinal blood flow via the diacylglycerol-protein kinase C pathway.
The American journal of physiology 1995;269(2 Pt 1):E239-46.
1995: Sven-Erik Bursell; Allen Clermont; B Oren; George L King
The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats.
Investigative ophthalmology & visual science 1995;36(3):596-607.
1994: Allen Clermont; M Brittis; T Shiba; T McGovern; George L King; Sven-Erik Bursell
Normalization of retinal blood flow in diabetic rats with primary intervention using insulin pumps.
Investigative ophthalmology & visual science 1994;35(3):981-90.
1993: Y D Halvorsen; Sven-Erik Bursell; W O Wilkison; Allen Clermont; M Brittis; T J McGovern; Bruce M Spiegelman
Vasodilation of rat retinal microvessels induced by monobutyrin. Dysregulation in diabetes.
The Journal of clinical investigation 1993;92(6):2872-6.
1992: Sven-Erik Bursell; Allen Clermont; T Shiba; George L King
Evaluating retinal circulation using video fluorescein angiography in control and diabetic rats.
Current eye research 1992;11(4):287-95.