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John Cleveland

Research Profile

Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Genes, myc

Anatomy

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Molecular Sequence Data

Physiology

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Cell Transformation, Neoplastic

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Yasmine A Valentin-Vega; John L Cleveland; Frank C Dorsey; Douglas R Green; Kirsteen H Maclean; Sandra Milasta; Meredith Steeves; Jacqueline Tait-Mulder; Michael B Kastan
Mitochondrial dysfunction in ataxia-telangiectasia.
Joung Hyuck Joo; Aashish Joshi; Chang Hwa Jung; Do-Hyung Kim; John L Cleveland; Frank C Dorsey; Kristin M Hennessy-Walters; Rekha Iyengar; Kelly McCastlain; Paul A Ney; Stephanie M Prater; Kristie L Rose; Meredith A Steeves; Der Fen Suen; Craig B Thompson; Chia-Ying Yang; Richard J Youle; Ji Zhang; Mondira Kundu
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.
ji zhang; Mindy S Randall; Melanie R Loyd; Frank C Dorsey; Mondira Kundu; John L Cleveland; Paul A Ney
Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation.

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2012: Yasmine A Valentin-Vega; John L Cleveland; Frank C Dorsey; Douglas R Green; Kirsteen H Maclean; Sandra Milasta; Meredith Steeves; Jacqueline Tait-Mulder; Michael B Kastan
Mitochondrial dysfunction in ataxia-telangiectasia.
Blood 2012;119(6):1490-500.
2011: Joung Hyuck Joo; Aashish Joshi; Chang Hwa Jung; Do-Hyung Kim; John L Cleveland; Frank C Dorsey; Kristin M Hennessy-Walters; Rekha Iyengar; Kelly McCastlain; Paul A Ney; Stephanie M Prater; Kristie L Rose; Meredith A Steeves; Der Fen Suen; Craig B Thompson; Chia-Ying Yang; Richard J Youle; Ji Zhang; Mondira Kundu
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy.
Molecular cell 2011;43(4):572-85.
2009: ji zhang; Mindy S Randall; Melanie R Loyd; Frank C Dorsey; Mondira Kundu; John L Cleveland; Paul A Ney
Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation.
Blood 2009;114(1):157-64.
2008: Steffan Nawrocki; Jennifer Carew; Kirsteen H Maclean; James F Courage; Peng Huang; Janet A Houghton; John L Cleveland; Francis Giles; David J McConkey
Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA.
Blood 2008;112(7):2917-26.
2008: Sean P Garrison; John R Jeffers; Chunying Yang; Jonas A Nilsson; Mark A Hall; Jerold E Rehg; Wen Yue; Jian Yu; Lin Zhang; Mihaela Onciu; Jeffery T Sample; John L Cleveland; Gerard P Zambetti
Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis.
Molecular and cellular biology 2008;28(17):5391-402.
2008: Jennifer Carew; Steffan Nawrocki; Venudhar Reddy; Dorothy Bush; Jerold E Rehg; Andrew Goodwin; Janet A Houghton; Robert A Casero; Laurence J Marton; John L Cleveland
The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib.
Cancer research 2008;68(12):4783-90.
2008: Jennifer Carew; Steffan Nawrocki; Francis Giles; John L Cleveland
Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance.
Biologics : targets & therapy 2008;2(2):201-4.
2008: Claudia Rodrigues; Steve T Nerlick; Elsie L White; John L Cleveland; Mary Lou King
A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development.
Development (Cambridge, England) 2008;135(11):1903-11.
2008: Kirsteen H Maclean; Frank C Dorsey; John L Cleveland; Michael B Kastan
Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
The Journal of clinical investigation 2008;118(1):79-88.
2007: Miguel A Sanjuan; Christopher P Dillon; Stephen W G Tait; Simon Moshiach; Frank C Dorsey; Samuel Connell; Masaaki Komatsu; Keiji Tanaka; John L Cleveland; Sebo Withoff; Douglas R Green
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis.
Nature 2007;450(7173):1253-7.
2007: Rachel L Schweers; ji zhang; Mindy S Randall; Melanie R Loyd; Weimin Li; Frank C Dorsey; Mondira Kundu; Joseph T Opferman; John L Cleveland; Jeffery L Miller; Paul A Ney
NIX is required for programmed mitochondrial clearance during reticulocyte maturation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19500-5.
2007: Jennifer Carew; Steffan Nawrocki; John L Cleveland
Modulating autophagy for therapeutic benefit.
Autophagy 2007;3(5):464-7.
2007: Steffan Nawrocki; Jennifer Carew; Leslie Douglas; John L Cleveland; Robin Humphreys; Janet A Houghton
Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Cancer research 2007;67(14):6987-94.
2007: Kirsteen H Maclean; Michael B Kastan; John L Cleveland
Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis.
Molecular cancer research : MCR 2007;5(7):705-11.
2007: Jennifer Carew; Steffan Nawrocki; Charissa N Kahue; Hui Zhang; Chunying Yang; Linda Chung; Janet A Houghton; Peng Huang; Francis Giles; John L Cleveland
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance.
Blood 2007;110(1):313-22.
2007: Ulrich B Keller; Jennifer B Old; Frank C Dorsey; Jonas A Nilsson; Lisa Nilsson; Kirsteen H Maclean; Linda Chung; Chunying Yang; Charles H. Spruck; Kelli Boyd; Steven I Reed; John L Cleveland
Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.
The EMBO journal 2007;26(10):2562-74.
2007: Philippe R J Bois; Kamel Izeradjene; Peter J Houghton; John L Cleveland; Janet A Houghton; Gerard C Grosveldz
FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.
The Journal of cell biology 2007;177(3):563.
2007: Lisa M Nilsson; Ulrich B Keller; Chunying Yang; Jonas A Nilsson; John L Cleveland; Martine F Roussel
Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis.
Oncogene 2007;26(20):2833-9.
2005: Isabel Moreno-Miralles; Ling Pan; Jennifer Keates-Baleeiro; Kristie Durst-Goodwin; Chunying Yang; Hyung-Gyoon Kim; Mary Ann Thompson; Christopher A Klug; John L Cleveland; Scott W Hiebert
The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia.
The Journal of biological chemistry 2005;280(48):40097-103.
2005: Lawryn H Kasper; Fayçal Boussouar; Kelli Boyd; Wu Xu; Michelle Biesen; Jerold E Rehg; Troy A Baudino; John L Cleveland; Paul K Brindle
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.
The EMBO journal 2005;24(22):3846-58.
2005: Ulrich B Keller; Jonas A Nilsson; Kirsteen H Maclean; Jennifer B Old; John L Cleveland
Nfkb 1 is dispensable for Myc-induced lymphomagenesis.
Oncogene 2005;24(41):6231-40.
2005: Philippe R J Bois; Kamel Izeradjene; Peter J Houghton; John L Cleveland; Janet A Houghton; Gerard C Grosveld
FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.
The Journal of cell biology 2005;170(6):903-12.
2005: Philippe R J Bois; Vanessa F Brochard; Adèle V A Salin-Cantegrel; John L Cleveland; Gerard C Grosveld
FoxO1a-cyclic GMP-dependent kinase I interactions orchestrate myoblast fusion.
Molecular and cellular biology 2005;25(17):7645-56.
2005: Glen C Ulett; Kirsteen H Maclean; Sunitha Nekkalapu; John L Cleveland; Elisabeth E Adderson
Mechanisms of group B streptococcal-induced apoptosis of murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2555-62.
2005: Jonas A Nilsson; Ulrich B Keller; Troy A Baudino; Chunying Yang; Sara Norton; Jennifer A Old; Lisa M Nilsson; Geoffrey Neale; Debora L Kramer; Carl W Porter; John L Cleveland
Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.
Cancer cell 2005;7(5):433-44.
2004: Jonas A Nilsson; Lisa M Nilsson; Ulrich B Keller; Yoshifumi Yokota; Kelli Boyd; John L Cleveland
Id2 is dispensable for myc-induced lymphomagenesis.
Cancer research 2004;64(20):7296-301.
2004: John L Cleveland; Charles J Sherr
Antagonism of Myc functions by Arf.
Cancer cell 2004;6(4):309-11.
2004: Jonas A Nilsson; John L Cleveland
Mnt: master regulator of the Max network.
Cell cycle (Georgetown, Tex.) 2004;3(5):588-90.
2004: Jonas A Nilsson; Kirsteen H Maclean; Ulrich B Keller; Hélène Pendeville; Troy A Baudino; John L Cleveland
Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation.
Molecular and cellular biology 2004;24(4):1560-9.
2003: Frederique Zindy; Richard Williams; Troy A Baudino; Jerold E Rehg; Stephen Xavier Skapek; John L Cleveland; Martine F Roussel; Charles J Sherr
Arf tumor suppressor promoter monitors latent oncogenic signals in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15930-5.
2003: Jonas A Nilsson; John L Cleveland
Myc pathways provoking cell suicide and cancer.
Oncogene 2003;22(56):9007-21.
2003: John R Jeffers; Evan Parganas; youngsoo Lee; Chunying Yang; JinLing Wang; Jennifer Brennan; Kirsteen H Maclean; Jiawen Han; Thomas Chittenden; James N Ihle; Peter J McKinnon; John L Cleveland; Gerard P Zambetti
Puma is an essential mediator of p53-dependent and -independent apoptotic pathways.
Cancer cell 2003;4(4):321-8.
2003: Kirsteen H Maclean; Ulrich B Keller; Carlos Rodriguez-Galindo; Jonas A Nilsson; John L Cleveland
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL.
Molecular and cellular biology 2003;23(20):7256-70.
2003: Troy A Baudino; Kirsteen H Maclean; Jennifer Brennan; Evan Parganas; Chunying Yang; Aaron S. Aslanian; Jacqueline A Lees; Charles J Sherr; Martine F Roussel; John L Cleveland
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.
Molecular cell 2003;11(4):905-14.
2003: Jodi R Alt; Timothy C Greiner; John L Cleveland; Christine M Eischen
Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.
The EMBO journal 2003;22(6):1442-50.
2002: Troy A Baudino; Catriona McKay; Helene Pendeville-Samain; Jonas A Nilsson; Kirsteen H Maclean; Elsie L White; Ann C Davis; James N Ihle; John L Cleveland
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression.
Genes & development 2002;16(19):2530-43.
2002: Christina M Barrett; Felicia L Lewis; J Brent Roaten; Trevor W Sweatman; Mervyn Israel; John L Cleveland; Leonard Lothstein
Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis.
Molecular cancer therapeutics 2002;1(7):469-81.
2002: Christine M Eischen; Jerold E Rehg; Stanley J Korsmeyer; John L Cleveland
Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Cancer research 2002;62(7):2184-91.
2002: Brian E Fee; Christina A Doyle; John L Cleveland
A novel Eyes Absent 2 protein is expressed in the human eye.
Gene 2002;285(1-2):221-8.
2002: S Wesley Clark; Brian E Fee; John L Cleveland
Misexpression of the eyes absent family triggers the apoptotic program.
The Journal of biological chemistry 2002;277(5):3560-7.
2002: Johann S Braun; Jack Sublett; Dorette Freyer; Tim Mitchell; John L Cleveland; Elaine I Tuomanen; Joerg R Weber
Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis.
The Journal of clinical investigation 2002;109(1):19-27.
2001: K H Maclean; John L Cleveland; J B Porter
Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes.
Blood 2001;98(13):3831-9.
2001: Johann S Braun; Rodger Novak; Peter J Murray; Christine M Eischen; S A Susin; G Kroemer; Annett Halle; Joerg R Weber; Elaine I Tuomanen; John L Cleveland
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus.
The Journal of infectious diseases 2001;184(10):1300-9.
2001: Christine M Eischen; Martine F Roussel; Stanley J Korsmeyer; John L Cleveland
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Molecular and cellular biology 2001;21(22):7653-62.
2001: Christine M Eischen; Graham Packham; John Nip; Brian E Fee; Scott W Hiebert; Gerard P Zambetti; John L Cleveland
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
Oncogene 2001;20(48):6983-93.
2001: Hélène Pendeville; Nick Carpino; Jean-Christophe Marine; Yutaka Takahashi; Marc Muller; J A Martial; John L Cleveland
The ornithine decarboxylase gene is essential for cell survival during early murine development.
Molecular and cellular biology 2001;21(19):6549-58.
2001: Christine M Eischen; David D Woo; Martine F Roussel; John L Cleveland
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Molecular and cellular biology 2001;21(15):5063-70.
2001: K Maclean; H Yang; John L Cleveland
Serum suppresses myeloid progenitor apoptosis by regulating iron homeostasis.
Journal of cellular biochemistry 2001;82(1):171-86.
2001: John Nip; DK Strom; Christine M Eischen; John L Cleveland; Gerard P Zambetti; Scott W Hiebert
E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation.
Oncogene 2001;20(8):910-20.
2001: Troy A Baudino; John L Cleveland
The Max network gone mad.
Molecular and cellular biology 2001;21(3):691-702.
2001: Renren Wen; Denan Wang; Catriona McKay; Kevin D Bunting; Jean-Christophe Marine; E F Vanin; Gerard P Zambetti; Stanley J Korsmeyer; James N Ihle; John L Cleveland
Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development.
Molecular and cellular biology 2001;21(2):678-89.
2000: Jodi R Alt; John L Cleveland; Mark Hannink; J Alan Diehl
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation.
Genes & development 2000;14(24):3102-14.
2000: K Inoue; R Wen; Jerold E Rehg; M Adachi; John L Cleveland; Martine F Roussel; Charles J Sherr
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis.
Genes & development 2000;14(14):1797-809.
2000: Denan Wang; J Feng; Renren Wen; Jean-Christophe Marine; Mark Y Sangster; Evan Parganas; Angelika Hoffmeyer; C W Jackson; John L Cleveland; Peter J Murray; James N Ihle
Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors.
Immunity 2000;13(1):25-35.
1999: Christine M Eischen; Jason D. Weber; Martine F Roussel; Charles J Sherr; John L Cleveland
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Genes & development 1999;13(20):2658-69.
1999: H Dai; Debora L Kramer; Chunying Yang; K Gopal Murti; Carl W Porter; John L Cleveland
The polyamine oxidase inhibitor MDL-72,527 selectively induces apoptosis of transformed hematopoietic cells through lysosomotropic effects.
Cancer research 1999;59(19):4944-54.
1999: Johann S Braun; Rodger Novak; Karl-Heinz Herzog; S M Bodner; John L Cleveland; Elaine I Tuomanen
Neuroprotection by a caspase inhibitor in acute bacterial meningitis.
Nature medicine 1999;5(3):298-302.
1998: Graham Packham; E L White; Christine M Eischen; H Yang; Evan Parganas; James N Ihle; DA Grillot; Gerard P Zambetti; Gabriel Nuñez; John L Cleveland
Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.
Genes & development 1998;12(16):2475-87.
1998: Frederique Zindy; Christine M Eischen; DH Randle; T Kamijo; John L Cleveland; Charles J Sherr; Martine F Roussel
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.
Genes & development 1998;12(15):2424-33.
1998: M W Frazier; X He; Jina Wang; Z Gu; John L Cleveland; Gerard P Zambetti
Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain.
Molecular and cellular biology 1998;18(7):3735-43.
1998: F W Quelle; J Wang; Jian Feng; Denan Wang; John L Cleveland; James N Ihle; Gerard P Zambetti
Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways.
Genes & development 1998;12(8):1099-107.
1998: DK Strom; John L Cleveland; Srikumar Chellappan; John Nip; Scott W Hiebert
E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(1):59-69.
1997: Joseph W Brewer; John L Cleveland; Linda M Hendershot
A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells.
The EMBO journal 1997;16(23):7207-16.
1997: Graham Packham; John L Cleveland
Induction of ornithine decarboxylase by IL-3 is mediated by sequential c-Myc-independent and c-Myc-dependent pathways.
Oncogene 1997;15(10):1219-32.
1997: John Nip; DK Strom; Brian E Fee; Gerard P Zambetti; John L Cleveland; Scott W Hiebert
E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis.
Molecular and cellular biology 1997;17(3):1049-56.
1997: Graham Packham; Jill Lahti; Brian E Fee; JM Gawn; E Coustan-Smith; D Campana; I Douglas; Vincent J Kidd; S Ghosh; John L Cleveland
Fas activates NF-kappaB and induces apoptosis in T-cell lines by signaling pathways distinct from those induced by TNF-alpha.
Cell death and differentiation 1997;4(2):130-9.
1996: Graham Packham; C W Porter; John L Cleveland
c-Myc induces apoptosis and cell cycle progression by separable, yet overlapping, pathways.
Oncogene 1996;13(3):461-9.
1996: Graham Packham; R A Ashmun; John L Cleveland
Cytokines suppress apoptosis independent of increases in reactive oxygen levels.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2792-800.
1995: Scott W Hiebert; Graham Packham; DK Strom; R Haffner; M Oren; G Zambetti; John L Cleveland
E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis.
Molecular and cellular biology 1995;15(12):6864-74.
1995: S Katzav; Graham Packham; M Sutherland; P Aroca; Eugenio Santos; John L Cleveland
Vav and Ras induce fibroblast transformation by overlapping signaling pathways which require c-Myc function.
Oncogene 1995;11(6):1079-88.
1995: Graham Packham; John L Cleveland
c-Myc and apoptosis.
Biochimica et biophysica acta 1995;1242(1):11-28.
1995: T Matsugi; B L Kreider; R Delwel; John L Cleveland; David S Askew; James N Ihle
The Evi-1 zinc finger myeloid transforming protein binds to genomic fragments containing (GATA)n sequences.
Oncogene 1995;11(1):191-8.
1995: F W Quelle; K Shimoda; William E Thierfelder; C Fischer; A Kim; S M Ruben; John L Cleveland; JH Pierce; Achsah D Keegan; Keats Nelms
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.
Molecular and cellular biology 1995;15(6):3336-43.
1995: Y Weinstein; David S Askew; O Miura; John L Cleveland; J N Ihle
Regulation of T cell receptor gamma gene expression by cytokines in murine hematopoietic cells.
European cytokine network 1995;6(2):97-102.
1995: Graham Packham; John L Cleveland
The role of ornithine decarboxylase in c-Myc-induced apoptosis.
Current topics in microbiology and immunology 1995;194():283-90.
1994: Graham Packham; John L Cleveland
Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis.
Molecular and cellular biology 1994;14(9):5741-7.
1994: John L Cleveland; J Troppmair; Graham Packham; David S Askew; P Lloyd; M González-Garcia; Gabriel Nuñez; James N Ihle; U R Rapp
v-raf suppresses apoptosis and promotes growth of interleukin-3-dependent myeloid cells.
Oncogene 1994;9(8):2217-26.
1994: Martine F Roussel; James Davis; John L Cleveland; J Ghysdael; Scott W Hiebert
Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1.
Oncogene 1994;9(2):405-15.
1994: Graham Packham; C Bello-Fernandez; John L Cleveland
Position and orientation independent transactivation by c-Myc.
Cellular & molecular biology research 1994;40(7-8):699-706.
1993: David S Askew; James N Ihle; John L Cleveland
Activation of apoptosis associated with enforced myc expression in myeloid progenitor cells is dominant to the suppression of apoptosis by interleukin-3 or erythropoietin.
Blood 1993;82(7):2079-87.
1993: O Silvennoinen; bruce witthuhn; F W Quelle; John L Cleveland; T Yi; James N Ihle
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8429-33.
1993: C Bello-Fernandez; Graham Packham; John L Cleveland
The ornithine decarboxylase gene is a transcriptional target of c-Myc.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7804-8.
1993: Osamu Miura; John L Cleveland; James N Ihle
Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors.
Molecular and cellular biology 1993;13(3):1788-95.
1992: Charles O Rock; John L Cleveland; Suzanne Jackowski
Macrophage growth arrest by cyclic AMP defines a distinct checkpoint in the mid-G1 stage of the cell cycle and overrides constitutive c-myc expression.
Molecular and cellular biology 1992;12(5):2351-8.
1992: T L Yi; John L Cleveland; James N Ihle
Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.
Molecular and cellular biology 1992;12(2):836-46.
1992: J Troppmair; John L Cleveland; David S Askew; U R Rapp
v-Raf/v-Myc synergism in abrogation of IL-3 dependence: v-Raf suppresses apoptosis.
Current topics in microbiology and immunology 1992;182():453-60.
1992: C Bello-Fernandez; John L Cleveland
c-myc transactivates the ornithine decarboxylase gene.
Current topics in microbiology and immunology 1992;182():445-52.
1991: T Yi; John L Cleveland; James N Ihle
Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification.
Blood 1991;78(9):2222-8.
1991: David S Askew; R A Ashmun; B C Simmons; John L Cleveland
Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.
Oncogene 1991;6(10):1915-22.
1991: Martine F Roussel; John L Cleveland; Sheila A Shurtleff; Charles J Sherr
Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling.
Nature 1991;353(6342):361-3.
1991: S Katzav; John L Cleveland; H E Heslop; D Pulido
Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential.
Molecular and cellular biology 1991;11(4):1912-20.
1990: Gisela Heidecker; Mahmoud Huleihel; John L Cleveland; Walter Kolch; T W Beck; P Lloyd; T Pawson; U R Rapp
Mutational activation of c-raf-1 and definition of the minimal transforming sequence.
Molecular and cellular biology 1990;10(6):2503-12.
1990: Stephen M Storm; John L Cleveland; U R Rapp
Expression of raf family proto-oncogenes in normal mouse tissues.
Oncogene 1990;5(3):345-51.
1989: John L Cleveland; M Dean; N Rosenberg; J Y Wang; U R Rapp
Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl.
Molecular and cellular biology 1989;9(12):5685-95.
1988: U R Rapp; Gisela Heidecker; Mahmoud Huleihel; John L Cleveland; W C Choi; T Pawson; J N Ihle; W B Anderson
raf family serine/threonine protein kinases in mitogen signal transduction.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():173-84.
1988: John L Cleveland; Mahmoud Huleihel; P Bressler; Ulrich Siebenlist; L Akiyama; Robert N Eisenman; U R Rapp
Negative regulation of c-myc transcription involves myc family proteins.
Oncogene research 1988;3(4):357-75.
1987: Y Weinstein; John L Cleveland; David S Askew; U R Rapp; J N Ihle
Insertion and truncation of c-myb by murine leukemia virus in a myeloid cell line derived from cultures of normal hematopoietic cells.
Journal of virology 1987;61(7):2339-43.
1987: U R Rapp; Stephen M Storm; John L Cleveland
Oncogenes: clinical relevance.
Haematology and blood transfusion 1987;31():450-9.
1986: U R Rapp; John L Cleveland; Stephen M Storm; T W Beck; Mahmoud Huleihel
Transformation by raf and myc oncogenes.
Princess Takamatsu symposia 1986;17():55-74.
1986: John L Cleveland; Y Weinstein; J N Ihle; David S Askew; U R Rapp
Transformation and insertional mutagenesis in vitro of primary hematopoietic stem cell cultures.
Current topics in microbiology and immunology 1986;132():44-54.