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Don Clewell

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
16
An, Florence
13
Chow, Joseph
12
Vickerman, MM
10
Zervos, Marcus
9
Donabedian, Susan
8
Flannagan, Susan
8
Ike, Yasuyoshi
6
Francia, Victoria
6
Thal, LeeAnn
5
Sedgley, Christine
5
Su, Yan
4
De Boever, Erika
3
Perri, Mary Beth
3
Fujimoto, Shuhei
3
Lerner, Stephen

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Publications

TOP 3
Sedgley Christine M; Clewell Don B; Flannagan Susan E
Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis.
Flannagan Susan E; Clewell Don B; Sedgley Christine M
A "retrocidal" plasmid in Enterococcus faecalis: passage and protection.
Francia Maria Victoria; Weaver Keith E; Goicoechea Patricia; Tille Patricia; Clewell Don B
Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1.

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All Publications

2009: Sedgley Christine M; Clewell Don B; Flannagan Susan E
Plasmid pAMS1-encoded, bacteriocin-related "Siblicide" in Enterococcus faecalis.
Journal of bacteriology 2009;191(9):3183-8.
2008: Flannagan Susan E; Clewell Don B; Sedgley Christine M
A "retrocidal" plasmid in Enterococcus faecalis: passage and protection.
Plasmid 2008;59(3):217-30.
2007: Francia Maria Victoria; Weaver Keith E; Goicoechea Patricia; Tille Patricia; Clewell Don B
Characterization of an active partition system for the Enterococcus faecalis pheromone-responding plasmid pAD1.
Journal of bacteriology 2007;189(23):8546-55.
2007: Clewell Don B
Properties of Enterococcus faecalis plasmid pAD1, a member of a widely disseminated family of pheromone-responding, conjugative, virulence elements encoding cytolysin.
Plasmid 2007;58(3):205-27.
2005: Ozawa Yoshiyuki; De Boever Erika H; Clewell Don B
Enterococcus faecalis sex pheromone plasmid pAM373: analyses of TraA and evidence for its interaction with RpoB.
Plasmid 2005;54(1):57-69.
2005: Sedgley C M; Nagel A C; Shelburne C E; Clewell D B; Appelbe O; Molander A
Quantitative real-time PCR detection of oral Enterococcus faecalis in humans.
Archives of oral biology 2005;50(6):575-83.
2005: Sedgley C M; Molander A; Flannagan S E; Nagel A C; Appelbe O K; Clewell D B; Dahlén G
Virulence, phenotype and genotype characteristics of endodontic Enterococcus spp.
Oral microbiology and immunology 2005;20(1):10-9.
2004: Francia Maria Victoria; Fujimoto Shuhei; Tille Patricia; Weaver Keith E; Clewell Don B
Replication of Enterococcus faecalis pheromone-responding plasmid pAD1: location of the minimal replicon and oriV site and RepA involvement in initiation of replication.
Journal of bacteriology 2004;186(15):5003-16.
2004: Sedgley C M; Lennan S L; Clewell D B
Prevalence, phenotype and genotype of oral enterococci.
Oral microbiology and immunology 2004;19(2):95-101.
2003: Flannagan Susan E; Chow Joseph W; Donabedian Susan M; Brown William J; Perri Mary B; Zervos Marcus J; Ozawa Yoshiyuki; Clewell Don B
Plasmid content of a vancomycin-resistant Enterococcus faecalis isolate from a patient also colonized by Staphylococcus aureus with a VanA phenotype.
Antimicrobial agents and chemotherapy 2003;47(12):3954-9.
2003: Weigel Linda M; Clewell Don B; Gill Steven R; Clark Nancye C; McDougal Linda K; Flannagan Susan E; Kolonay James F; Shetty Jyoti; Killgore George E; Tenover Fred C
Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus.
Science (New York, N.Y.) 2003;302(5650):1569-71.
2002: Clewell Don B; Francia M Victoria; Flannagan Susan E; An Florence Y
Enterococcal plasmid transfer: sex pheromones, transfer origins, relaxases, and the Staphylococcus aureus issue.
Plasmid 2002;48(3):193-201.
2002: Lee Hae Kyung; Vakulenko Sergei B; Clewell Don B; Lerner Stephen A; Chow Joseph W
Mutations in the aph(2")-Ic gene are responsible for increased levels of aminoglycoside resistance.
Antimicrobial agents and chemotherapy 2002;46(10):3253-6.
2002: Tomita Haruyoshi; Pierson Carl; Lim Suk Kyung; Clewell Don B; Ike Yasuyoshi
Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium.
Journal of clinical microbiology 2002;40(9):3326-33.
2002: Francia M Victoria; Clewell Don B
Amplification of the tetracycline resistance determinant of pAMalpha1 in Enterococcus faecalis requires a site-specific recombination event involving relaxase.
Journal of bacteriology 2002;184(18):5187-93.
2002: Francia M Victoria; Clewell Don B
Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein.
Molecular microbiology 2002;45(2):375-95.
2002: Flannagan Susan E; Clewell Don B
Identification and characterization of genes encoding sex pheromone cAM373 activity in Enterococcus faecalis and Staphylococcus aureus.
Molecular microbiology 2002;44(3):803-17.
2002: An Florence Y; Clewell Don B
Identification of the cAD1 sex pheromone precursor in Enterococcus faecalis.
Journal of bacteriology 2002;184(7):1880-7.
2001: Hammerum A M; Flannagan S E; Clewell D B; Jensen L B
Indication of transposition of a mobile DNA element containing the vat(D) and erm(B) genes in Enterococcus faecium.
Antimicrobial agents and chemotherapy 2001;45(11):3223-5.
2001: Chow J W; Kak V; You I; Kao S J; Petrin J; Clewell D B; Lerner S A; Miller G H; Shaw K J
Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium.
Antimicrobial agents and chemotherapy 2001;45(10):2691-4.
2001: Francia M V; Haas W; Wirth R; Samberger E; Muscholl-Silberhorn A; Gilmore M S; Ike Y; Weaver K E; An F Y; Clewell D B
Completion of the nucleotide sequence of the Enterococcus faecalis conjugative virulence plasmid pAD1 and identification of a second transfer origin.
Plasmid 2001;46(2):117-27.
2001: Showsh S A; De Boever E H; Clewell D B
Vancomycin resistance plasmid in Enterococcus faecalis that encodes sensitivity to a sex pheromone also produced by Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2001;45(7):2177-8.
2001: De Boever E H; Clewell D B
The Enterococcus faecalis pheromone-responsive plasmid pAM373 does not encode an entry exclusion function.
Plasmid 2001;45(1):57-60.
2000: Kao S J; You I; Clewell D B; Donabedian S M; Zervos M J; Petrin J; Shaw K J; Chow J W
Detection of the high-level aminoglycoside resistance gene aph(2")-Ib in Enterococcus faecium.
Antimicrobial agents and chemotherapy 2000;44(10):2876-9.
2000: De Boever E H; Clewell D B; Fraser C M
Enterococcus faecalis conjugative plasmid pAM373: complete nucleotide sequence and genetic analyses of sex pheromone response.
Molecular microbiology 2000;37(6):1327-41.
2000: Kariyama R; Mitsuhata R; Chow J W; Clewell D B; Kumon H
Simple and reliable multiplex PCR assay for surveillance isolates of vancomycin-resistant enterococci.
Journal of clinical microbiology 2000;38(8):3092-5.
2000: Donabedian S; Hershberger E; Thal L A; Chow J W; Clewell D B; Robinson-Dunn B; Zervos M J
PCR fragment length polymorphism analysis of vancomycin-resistant Enterococcus faecium.
Journal of clinical microbiology 2000;38(8):2885-8.
2000: Tomita H; Clewell D B
A pAD1-encoded small RNA molecule, mD, negatively regulates Enterococcus faecalis pheromone response by enhancing transcription termination.
Journal of bacteriology 2000;182(4):1062-73.
2000: Clewell D B; An F Y; Flannagan S E; Antiporta M; Dunny G M
Enterococcal sex pheromone precursors are part of signal sequences for surface lipoproteins.
Molecular microbiology 2000;35(1):246-7.
1999: An F Y; Sulavik M C; Clewell D B
Identification and characterization of a determinant (eep) on the Enterococcus faecalis chromosome that is involved in production of the peptide sex pheromone cAD1.
Journal of bacteriology 1999;181(19):5915-21.
1999: Wu K; An F Y; Clewell D B
Enterococcus faecalis pheromone-responding plasmid pAD1 gives rise to an aggregation (clumping) response when cells are exposed to subinhibitory concentrations of chloramphenicol, erythromycin, or tetracycline.
Plasmid 1999;41(1):82-8.
1998: Chow J W; Donabedian S M; Clewell D B; Sahm D F; Zervos M J
In vitro susceptibility and molecular analysis of gentamicin-resistant enterococci.
Diagnostic microbiology and infectious disease 1998;32(3):141-6.
1998: Thal L; Donabedian S; Robinson-Dunn B; Chow J W; Dembry L; Clewell D B; Alshab D; Zervos M J
Molecular analysis of glycopeptide-resistant Enterococcus faecium isolates collected from Michigan hospitals over a 6-year period.
Journal of clinical microbiology 1998;36(11):3303-8.
1998: do Carmo de Freire Bastos M; Tomita H; Tanimoto K; Clewell D B
Regulation of the Enterococcus faecalis pAD1-related sex pheromone response: analyses of traD expression and its role in controlling conjugation functions.
Molecular microbiology 1998;30(2):381-92.
1998: Fujimoto S; Clewell D B
Regulation of the pAD1 sex pheromone response of Enterococcus faecalis by direct interaction between the cAD1 peptide mating signal and the negatively regulating, DNA-binding TraA protein.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6430-5.
1998: Tsai S F; Zervos M J; Clewell D B; Donabedian S M; Sahm D F; Chow J W
A new high-level gentamicin resistance gene, aph(2'')-Id, in Enterococcus spp.
Antimicrobial agents and chemotherapy 1998;42(5):1229-32.
1997: de Freire Bastos M C; Tanimoto K; Clewell D B
Regulation of transfer of the Enterococcus faecalis pheromone-responding plasmid pAD1: temperature-sensitive transfer mutants and identification of a new regulatory determinant, traD.
Journal of bacteriology 1997;179(10):3250-9.
1997: Vickerman M M; Clewell D B
Deletions in the carboxyl-terminal region of Streptococcus gordonii glucosyltransferase affect cell-associated enzyme activity and sucrose-associated accumulation of growing cells.
Applied and environmental microbiology 1997;63(5):1667-73.
1997: Vickerman M M; Jones G W; Clewell D B
Molecular analysis of representative Streptococcus gordonii Spp phase variants reveals no differences in the glucosyltransferase structural gene, gtfG.
Oral microbiology and immunology 1997;12(2):82-90.
1997: Chow J W; Zervos M J; Lerner S A; Thal L A; Donabedian S M; Jaworski D D; Tsai S; Shaw K J; Clewell D B
A novel gentamicin resistance gene in Enterococcus.
Antimicrobial agents and chemotherapy 1997;41(3):511-4.
1997: Fujimoto S; Bastos M; Tanimoto K; An F; Wu K; Clewell D B
The pAD1 sex pheromone response in Enterococcus faecalis.
Advances in experimental medicine and biology 1997;418():1037-40.
1997: Vickerman M M; Clewell D B
Regulation of Streptococcus gordonii glucosyltransferase.
Advances in experimental medicine and biology 1997;418():661-4.
1997: An F Y; Clewell D B
The origin of transfer (oriT) of the enterococcal, pheromone-responding, cytolysin plasmid pAD1 is located within the repA determinant.
Plasmid 1997;37(1):87-94.
1997: Vickerman M M; Sulavik M C; Nowak J D; Gardner N M; Jones G W; Clewell D B
Nucleotide sequence analysis of the Streptococcus gordonii glucosyltransferase gene, gtfG.
DNA sequence : the journal of DNA sequencing and mapping 1997;7(2):83-95.
1996: Vickerman M M; Sulavik M C; Minick P E; Clewell D B
Changes in the carboxyl-terminal repeat region affect extracellular activity and glucan products of Streptococcus gordonii glucosyltransferase.
Infection and immunity 1996;64(12):5117-28.
1996: Jaworski D D; Flannagan S E; Clewell D B
Analyses of traA, int-Tn, and xis-Tn mutations in the conjugative transposon Tn916 in Enterococcus faecalis.
Plasmid 1996;36(3):201-8.
1996: Sulavik M C; Clewell D B
Rgg is a positive transcriptional regulator of the Streptococcus gordonii gtfG gene.
Journal of bacteriology 1996;178(19):5826-30.
1996: Jones G W; Clewell D B; Charles L G; Vickerman M M
Multiple phase variation in haemolytic, adhesive and antigenic properties of Streptococcus gordonii.
Microbiology (Reading, England) 1996;142 ( Pt 1)():181-9.
1995: Jaworski D D; Clewell D B
A functional origin of transfer (oriT) on the conjugative transposon Tn916.
Journal of bacteriology 1995;177(22):6644-51.
1995: Vickerman M M; Sulavik M C; Clewell D B
Oral streptococci with genetic determinants similar to the glucosyltransferase regulatory gene, rgg.
Infection and immunity 1995;63(11):4524-7.
1995: Heath D G; An F Y; Weaver K E; Clewell D B
Phase variation of Enterococcus faecalis pAD1 conjugation functions relates to changes in iteron sequence region.
Journal of bacteriology 1995;177(19):5453-9.
1995: Clewell D B; Flannagan S E; Jaworski D D
Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons.
Trends in microbiology 1995;3(6):229-36.
1995: Vickerman M M; Sulavik M C; Clewell D B
Molecular analysis of Streptococcus gordonii glucosyltransferase phase variants.
Developments in biological standardization 1995;85():309-14.
1995: Clewell D B; Jaworski D D; Flannagan S E; Zitzow L A; Su Y A
The conjugative transposon Tn916 of Enterococcus faecalis: structural analysis and some key factors involved in movement.
Developments in biological standardization 1995;85():11-7.
1994: Gilmore M S; Segarra R A; Booth M C; Bogie C P; Hall L R; Clewell D B
Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants.
Journal of bacteriology 1994;176(23):7335-44.
1994: Flannagan S E; Zitzow L A; Su Y A; Clewell D B
Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis.
Plasmid 1994;32(3):350-4.
1994: Jaworski D D; Clewell D B
Evidence that coupling sequences play a frequency-determining role in conjugative transposition of Tn916 in Enterococcus faecalis.
Journal of bacteriology 1994;176(11):3328-35.
1994: Thal L A; Chow J W; Clewell D B; Zervos M J
Tn924, a chromosome-borne transposon encoding high-level gentamicin resistance in Enterococcus faecalis.
Antimicrobial agents and chemotherapy 1994;38(5):1152-6.
1994: An F Y; Clewell D B
Characterization of the determinant (traB) encoding sex pheromone shutdown by the hemolysin/bacteriocin plasmid pAD1 in Enterococcus faecalis.
Plasmid 1994;31(2):215-21.
1993: Su Y A; Clewell D B
Characterization of the left 4 kb of conjugative transposon Tn916: determinants involved in excision.
Plasmid 1993;30(3):234-50.
1993: Chow J W; Thal L A; Perri M B; Vazquez J A; Donabedian S M; Clewell D B; Zervos M J
Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis.
Antimicrobial agents and chemotherapy 1993;37(11):2474-7.
1993: Vickerman M M; Heath D G; Clewell D B
Construction of recombination-deficient strains of Streptococcus gordonii by disruption of the recA gene.
Journal of bacteriology 1993;175(19):6354-7.
1993: Tanimoto K; An F Y; Clewell D B
Characterization of the traC determinant of the Enterococcus faecalis hemolysin-bacteriocin plasmid pAD1: binding of sex pheromone.
Journal of bacteriology 1993;175(16):5260-4.
1993: Clewell D B
Bacterial sex pheromone-induced plasmid transfer.
Cell 1993;73(1):9-12.
1993: Weaver K E; Clewell D B; An F
Identification, characterization, and nucleotide sequence of a region of Enterococcus faecalis pheromone-responsive plasmid pAD1 capable of autonomous replication.
Journal of bacteriology 1993;175(7):1900-9.
1993: Tanimoto K; Clewell D B
Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: expression of the positive regulator TraE1.
Journal of bacteriology 1993;175(4):1008-18.
1993: Thal L A; Chow J W; Patterson J E; Perri M B; Donabedian S; Clewell D B; Zervos M J
Molecular characterization of highly gentamicin-resistant Enterococcus faecalis isolates lacking high-level streptomycin resistance.
Antimicrobial agents and chemotherapy 1993;37(1):134-7.
1992: Ike Y; Clewell D B
Evidence that the hemolysin/bacteriocin phenotype of Enterococcus faecalis subsp. zymogenes can be determined by plasmids in different incompatibility groups as well as by the chromosome.
Journal of bacteriology 1992;174(24):8172-7.
1992: Sulavik M C; Tardif G; Clewell D B
Identification of a gene, rgg, which regulates expression of glucosyltransferase and influences the Spp phenotype of Streptococcus gordonii Challis.
Journal of bacteriology 1992;174(11):3577-86.
1992: Pontius L T; Clewell D B
Conjugative transfer of Enterococcus faecalis plasmid pAD1: nucleotide sequence and transcriptional fusion analysis of a region involved in positive regulation.
Journal of bacteriology 1992;174(10):3152-60.
1992: Vickerman M M; Clewell D B; Jones G W
Glucosyltransferase phase variation in Streptococcus gordonii modifies adhesion to saliva-coated hydroxyapatite surfaces in a sucrose-independent manner.
Oral microbiology and immunology 1992;7(2):118-20.
1992: Su Y A; He P; Clewell D B
Characterization of the tet(M) determinant of Tn916: evidence for regulation by transcription attenuation.
Antimicrobial agents and chemotherapy 1992;36(4):769-78.
1992: Pontius L T; Clewell D B
Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: nucleotide sequence analysis of traA.
Journal of bacteriology 1992;174(6):1821-7.
1992: Ike Y; Flannagan S E; Clewell D B
Hyperhemolytic phenomena associated with insertions of Tn916 into the hemolysin determinant of Enterococcus faecalis plasmid pAD1.
Journal of bacteriology 1992;174(6):1801-9.
1991: Vickerman M M; Clewell D B; Jones G W
Ecological implications of glucosyltransferase phase variation in Streptococcus gordonii.
Applied and environmental microbiology 1991;57(12):3648-51.
1991: Pontius L T; Clewell D B
A phase variation event that activates conjugation functions encoded by the Enterococcus faecalis plasmid pAD1.
Plasmid 1991;26(3):172-85.
1991: Flannagan S E; Clewell D B
Conjugative transfer of Tn916 in Enterococcus faecalis: trans activation of homologous transposons.
Journal of bacteriology 1991;173(22):7136-41.
1991: Vickerman M M; Clewell D B; Jones G W
Sucrose-promoted accumulation of growing glucosyltransferase variants of Streptococcus gordonii on hydroxyapatite surfaces.
Infection and immunity 1991;59(10):3523-30.
1991: Weaver K E; Clewell D B
Control of Enterococcus faecalis sex pheromone cAD1 elaboration: effects of culture aeration and pAD1 plasmid-encoded determinants.
Plasmid 1991;25(3):177-89.
1991: An F Y; Clewell D B
Tn917 transposase. Sequence correction reveals a single open reading frame corresponding to the tnpA determinant of Tn3-family elements.
Plasmid 1991;25(2):121-4.
1991: Su Y A; Sulavik M C; He P; Makinen K K; Makinen P L; Fiedler S; Wirth R; Clewell D B
Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens.
Infection and immunity 1991;59(1):415-20.
1990: Clewell D B; Pontius L T; An F Y; Ike Y; Suzuki A; Nakayama J
Nucleotide sequence of the sex pheromone inhibitor (iAD1) determinant of Enterococcus faecalis conjugative plasmid pAD1.
Plasmid 1990;24(2):156-61.
1990: Weaver K E; Clewell D B
Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: effects of host strain and traA, traB, and C region mutants on expression of an E region pheromone-inducible lacZ fusion.
Journal of bacteriology 1990;172(5):2633-41.
1990: Clewell D B
Movable genetic elements and antibiotic resistance in enterococci.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1990;9(2):90-102.
1990: Ike Y; Clewell D B; Segarra R A; Gilmore M S
Genetic analysis of the pAD1 hemolysin/bacteriocin determinant in Enterococcus faecalis: Tn917 insertional mutagenesis and cloning.
Journal of bacteriology 1990;172(1):155-63.
1989: Tardif G; Sulavik M C; Jones G W; Clewell D B
Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis.
Infection and immunity 1989;57(12):3945-8.
1989: Weaver K E; Clewell D B
Construction of Enterococcus faecalis pAD1 miniplasmids: identification of a minimal pheromone response regulatory region and evaluation of a novel pheromone-dependent growth inhibition.
Plasmid 1989;22(2):106-19.
1989: Clewell D B; Weaver K E
Sex pheromones and plasmid transfer in Enterococcus faecalis.
Plasmid 1989;21(3):175-84.
1989: Mäkinen P L; Clewell D B; An F; Mäkinen K K
Purification and substrate specificity of a strongly hydrophobic extracellular metalloendopeptidase ("gelatinase") from Streptococcus faecalis (strain 0G1-10).
The Journal of biological chemistry 1989;264(6):3325-34.
1988: Weaver K E; Clewell D B
Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: construction and characterization of lacZ transcriptional fusions in a key control region of the plasmid.
Journal of bacteriology 1988;170(9):4343-52.
1988: Clewell D B; Flannagan S E; Ike Y; Jones J M; Gawron-Burke C
Sequence analysis of termini of conjugative transposon Tn916.
Journal of bacteriology 1988;170(7):3046-52.
1988: Senghas E; Jones J M; Yamamoto M; Gawron-Burke C; Clewell D B
Genetic organization of the bacterial conjugative transposon Tn916.
Journal of bacteriology 1988;170(1):245-9.
1987: Yamamoto M; Jones J M; Senghas E; Gawron-Burke C; Clewell D B
Generation of Tn5 insertions in streptococcal conjugative transposon Tn916.
Applied and environmental microbiology 1987;53(5):1069-72.
1987: Clewell D B; An F Y; Mori M; Ike Y; Suzuki A
Streptococcus faecalis sex pheromone (cAD1) response: evidence that the peptide inhibitor excreted by pAD1-containing cells may be plasmid determined.
Plasmid 1987;17(1):65-8.

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