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Andrew Clifford

Research Profile

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Andrew J Clifford; Juan F Medrano; Alanna J Moshfegh; Janel E Owens; Gonzalo Rincon; David J Baer; Janet A Novotny
Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults.
Andrew J Clifford; James G Fadel; Dirk M Holstege; Seung-Hyun Kim; Bitao Liu; Laura McWade; Juan F Medrano; Alanna J Moshfegh; Hans-Georg Müller; David J Baer; Kehui Chen; Janel E Owens; Gonzalo Rincon; Janet A Novotny
Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.
Jennifer C Chuang; James G Fadel; Dirk M Holstege; Seung-Hyun Kim; Hosea D Matel; Krishnan P Nambiar; Andrew J Clifford
Quantitation of [5-14CH3]-(2R, 4'R, 8'R)-α-tocopherol in humans.

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All Publications

2013: Andrew J Clifford; Juan F Medrano; Alanna J Moshfegh; Janel E Owens; Gonzalo Rincon; David J Baer; Janet A Novotny
Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults.
Lipids in health and disease 2013;12():66.
2012: Andrew J Clifford; James G Fadel; Dirk M Holstege; Seung-Hyun Kim; Bitao Liu; Laura McWade; Juan F Medrano; Alanna J Moshfegh; Hans-Georg Müller; David J Baer; Kehui Chen; Janel E Owens; Gonzalo Rincon; Janet A Novotny
Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.
The Journal of nutrition 2012;142(9):1764-71.
2011: Jennifer C Chuang; James G Fadel; Dirk M Holstege; Seung-Hyun Kim; Hosea D Matel; Krishnan P Nambiar; Andrew J Clifford
Quantitation of [5-14CH3]-(2R, 4'R, 8'R)-α-tocopherol in humans.
The Journal of nutrition 2011;141(8):1482-8.
2011: Seung-Hyun Kim; Jennifer C Chuang; Peter B Kelly; Andrew J Clifford
Carbon isotopes profiles of human whole blood, plasma, red blood cells, urine and feces for biological/biomedical 14C-accelerator mass spectrometry applications.
Analytical chemistry 2011;83(9):3312-8.
2010: Seung-Hyun Kim; Peter B Kelly; Volkan Ortalan; Nigel D Browning; Andrew J Clifford
Quality of graphite target for biological/biomedical/environmental applications of 14C-accelerator mass spectrometry.
Analytical chemistry 2010;82(6):2243-52.
2009: Charlene C Ho; Fabiana F de Moura; Seung-Hyun Kim; Betty Jane Burri; Andrew J Clifford
A minute dose of 14C-{beta}-carotene is absorbed and converted to retinoids in humans.
The Journal of nutrition 2009;139(8):1480-6.
2009: Seung-Hyun Kim; Peter B Kelly; Andrew J Clifford
Accelerator mass spectrometry targets of submilligram carbonaceous samples using the high-throughput Zn reduction method.
Analytical chemistry 2009;81(14):5949-54.
2008: Seung-Hyun Kim; Peter B Kelly; Andrew J Clifford
Biological/biomedical accelerator mass spectrometry targets. 2. Physical, morphological, and structural characteristics.
Analytical chemistry 2008;80(20):7661-9.
2008: Seung-Hyun Kim; Peter B Kelly; Andrew J Clifford
Biological/biomedical accelerator mass spectrometry targets. 1. optimizing the CO2 reduction step using zinc dust.
Analytical chemistry 2008;80(20):7651-60.
2007: Janel E Owens; Dirk M Holstege; Andrew J Clifford
Comparison of two dietary folate intake instruments and their validation by RBC folate.
Journal of agricultural and food chemistry 2007;55(9):3737-40.
2007: Janel E Owens; Dirk M Holstege; Andrew J Clifford
High-throughput method for the quantitation of total folate in whole blood using LC-MS/MS.
Journal of agricultural and food chemistry 2007;55(9):3292-7.
2007: Charlene C Ho; Fabiana F de Moura; Seung-Hyun Kim; Andrew J Clifford
Excentral cleavage of beta-carotene in vivo in a healthy man.
The American journal of clinical nutrition 2007;85(3):770-7.
2006: Andrew J Clifford; Fabiana F de Moura; Charlene C Ho; Jennifer C Chuang; Jennifer R Follett; James G Fadel; Janet A Novotny
A feasibility study quantifying in vivo human alpha-tocopherol metabolism.
The American journal of clinical nutrition 2006;84(6):1430-41.
2005: Fabiana F de Moura; Charlene C Ho; Girma Getachew; Sabrina J Hickenbottom; Andrew J Clifford
Kinetics of 14C distribution after tracer dose of 14C-lutein in an adult woman.
Lipids 2005;40(10):1069-73.
2005: Janel E Owens; Dirk M Holstege; Andrew J Clifford
Quantitation of total folate in whole blood using LC-MS/MS.
Journal of agricultural and food chemistry 2005;53(19):7390-4.
2005: Susan E Ebeler; Karen H Dingley; Esther A Ubick; S Abel; Alyson E Mitchell; Stephanie A Burns; Francene M Steinberg; Andrew J Clifford
Animal models and analytical approaches for understanding the relationships between wine and cancer.
Drugs under experimental and clinical research 2005;31(1):19-27.
2005: Andrew J Clifford; Elizabeth M Noceti; Amy Block-Joy; Torin Block; Gladys Block
Erythrocyte folate and its response to folic acid supplementation is assay dependent in women.
The Journal of nutrition 2005;135(1):137-43.
2004: Betty Jane Burri; Andrew J Clifford
Carotenoid and retinoid metabolism: insights from isotope studies.
Archives of biochemistry and biophysics 2004;430(1):110-9.
2004: Yumei Lin; Stephen R Dueker; Jennifer R Follett; James G Fadel; Ali Arjomand; Philip D Schneider; Joshua Miller; Ralph Green; Bruce Buchholz; John S Vogel; Robert Phair; Andrew J Clifford
Quantitation of in vivo human folate metabolism.
The American journal of clinical nutrition 2004;80(3):680-91.
2003: Fang Yao; Hans-Georg Müller; Andrew J Clifford; Stephen R Dueker; Jennifer R Follett; Yumei Lin; Bruce Buchholz; John S Vogel
Shrinkage estimation for functional principal component scores with application to the population kinetics of plasma folate.
Biometrics 2003;59(3):676-85.
2003: Shawna L Lemke; Stephen R Dueker; Jennifer R Follett; Yumei Lin; Colleen Carkeet; Bruce Buchholz; John S Vogel; Andrew J Clifford
Absorption and retinol equivalence of beta-carotene in humans is influenced by dietary vitamin A intake.
Journal of lipid research 2003;44(8):1591-600.
2003: Elizabeth A Koutsos; Andrew J Clifford; Chris C Calvert; Kirk C Klasing
Maternal carotenoid status modifies the incorporation of dietary carotenoids into immune tissues of growing chickens (Gallus gallus domesticus).
The Journal of nutrition 2003;133(4):1132-8.
2003: Yumei Lin; Stephen R Dueker; Andrew J Clifford
Human whole blood folate analysis using a selected ion monitoring gas chromatography with mass selective detection protocol.
Analytical biochemistry 2003;312(2):255-7.
2003: Karen H Dingley; Esther A Ubick; Marina L Chiarappa-Zucca; Susan Nowell; Steffen Abel; Susan E Ebeler; Alyson E Mitchell; Stephanie A Burns; Francene M Steinberg; Andrew J Clifford
Effect of dietary constituents with chemopreventive potential on adduct formation of a low dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes.
Nutrition and cancer 2003;46(2):212-21.
2002: Hans-Georg Müller; Chun-Lung Su; Stephen R Dueker; Yumei Lin; Andrew J Clifford; Bruce Buchholz; John S Vogel
Semiparametric modeling of labeled-cell kinetics, with application to isotope labeling of erythrocytes.
Biometrics 2002;58(4):937-45.
2002: Susan E Ebeler; Charles A Brenneman; Gap-Soon Kim; William T Jewell; Michael R Webb; Leticia Chacon-Rodriguez; Emily A MacDonald; Amanda C Cramer; Andrew Levi; John D Ebeler; Alma Islas-Trejo; Amber Kraus; Steven H Hinrichs; Andrew J Clifford
Dietary catechin delays tumor onset in a transgenic mouse model.
The American journal of clinical nutrition 2002;76(4):865-72.
2002: Sabrina J Hickenbottom; Shawna L Lemke; Stephen R Dueker; Yumei Lin; Jennifer R Follett; Colleen Carkeet; Bruce Buchholz; John S Vogel; Andrew J Clifford
Dual isotope test for assessing beta-carotene cleavage to vitamin A in humans.
European journal of nutrition 2002;41(4):141-7.
2002: Sabrina J Hickenbottom; Jennifer R Follett; Yumei Lin; Stephen R Dueker; Betty Jane Burri; Terry R Neidlinger; Andrew J Clifford
Variability in conversion of beta-carotene to vitamin A in men as measured by using a double-tracer study design.
The American journal of clinical nutrition 2002;75(5):900-7.
2002: Jennine M Lunetta; Rebecca A Zulim; Stephen R Dueker; Yumei Lin; Vicky Flaig; Philip D Schneider; Bruce M Wolfe; Andrew J Clifford
Method for the simultaneous determination of retinol and beta-carotene concentrations in human tissues and plasma.
Analytical biochemistry 2002;304(1):100-9.
2002: Yumei Lin; Stephen R Dueker; A Daniel Jones; Andrew J Clifford
A parallel processing solid phase extraction protocol for the determination of whole blood folate.
Analytical biochemistry 2002;301(1):14-20.
2001: Betty Jane Burri; Terry R Neidlinger; Andrew J Clifford
Serum carotenoid depletion follows first-order kinetics in healthy adult women fed naturally low carotenoid diets.
The Journal of nutrition 2001;131(8):2096-100.
2000: Stephen R Dueker; Yumei Lin; Bruce Buchholz; Philip D Schneider; Michael W Lamé; Hank J Segall; John S Vogel; Andrew J Clifford
Long-term kinetic study of beta-carotene, using accelerator mass spectrometry in an adult volunteer.
Journal of lipid research 2000;41(11):1790-800.
2000: Stephen R Dueker; Yumei Lin; A Daniel Jones; RS Mercer; E Fabbro; Joshua Miller; Ralph Green; Andrew J Clifford
Determination of blood folate using acid extraction and internally standardized gas chromatography-mass spectrometry detection.
Analytical biochemistry 2000;283(2):266-75.
2000: Yumei Lin; Stephen R Dueker; Betty Jane Burri; Terry R Neidlinger; Andrew J Clifford
Variability of the conversion of beta-carotene to vitamin A in women measured by using a double-tracer study design.
The American journal of clinical nutrition 2000;71(6):1545-54.
1999: Bruce Buchholz; Ali Arjomand; Stephen R Dueker; Philip D Schneider; Andrew J Clifford; John S Vogel
Intrinsic erythrocyte labeling and attomole pharmacokinetic tracing of 14C-labeled folic acid with accelerator mass spectrometry.
Analytical biochemistry 1999;269(2):348-52.
1998: Yumei Lin; Betty Jane Burri; Terry R Neidlinger; Hans-Georg Müller; Stephen R Dueker; Andrew J Clifford
Estimating the concentration of beta-carotene required for maximal protection of low-density lipoproteins in women.
The American journal of clinical nutrition 1998;67(5):837-45.
1998: Stephen R Dueker; RS Mercer; A Daniel Jones; Andrew J Clifford
Ion trap mass spectrometry for kinetic studies of stable isotope labeled vitamin A at low enrichments.
Analytical chemistry 1998;70(7):1369-74.
1998: Stephen R Dueker; A Daniel Jones; Andrew J Clifford
Protocol development for biological tracer studies.
Advances in experimental medicine and biology 1998;445():363-78.
1998: Andrew J Clifford; Ali Arjomand; Stephen R Dueker; Philip D Schneider; Bruce Buchholz; John S Vogel
The dynamics of folic acid metabolism in an adult given a small tracer dose of 14C-folic acid.
Advances in experimental medicine and biology 1998;445():239-51.
1998: M R Facer; Hans-Georg Müller; Andrew J Clifford
Statistical models for quantitative bioassay.
Advances in experimental medicine and biology 1998;445():147-71.
1997: Susan E Ebeler; Andrew J Clifford; Takayuki Shibamoto
Quantitative analysis by gas chromatography of volatile carbonyl compounds in expired air from mice and human.
Journal of chromatography. B, Biomedical sciences and applications 1997;702(1-2):211-5.
1996: Andrew J Clifford; Susan E Ebeler; J D Ebeler; N D Bills; Steven H Hinrichs; P L Teissedre; Andrew L Waterhouse
Delayed tumor onset in transgenic mice fed an amino acid-based diet supplemented with red wine solids.
The American journal of clinical nutrition 1996;64(5):748-56.
1996: Hans-Georg Müller; M R Facer; N D Bills; Andrew J Clifford
Statistical interaction model for exchangeability of food folates in rat growth bioassay.
The Journal of nutrition 1996;126(10):2585-92.
1996: J A Novotny; L A Zech; Harold C Furr; Stephen R Dueker; Andrew J Clifford
Mathematical modeling in nutrition: constructing a physiologic compartmental model of the dynamics of beta-carotene metabolism.
Advances in food and nutrition research 1996;40():25-54.
1995: Sidney M Gospe; Dorothy W Gietzen; P J Summers; Jennine M Lunetta; Joshua Miller; J Selhub; William G Ellis; Andrew J Clifford
Behavioral and neurochemical changes in folate-deficient mice.
Physiology & behavior 1995;58(5):935-41.
1995: J A Novotny; Stephen R Dueker; L A Zech; Andrew J Clifford
Compartmental analysis of the dynamics of beta-carotene metabolism in an adult volunteer.
Journal of lipid research 1995;36(8):1825-38.
1995: Y Lin; Stephen R Dueker; A Daniel Jones; Susan E Ebeler; Andrew J Clifford
Protocol for collection and HPLC analysis of volatile carbonyl compounds in breath.
Clinical chemistry 1995;41(7):1028-32.
1994: Stephen R Dueker; A Daniel Jones; G M Smith; Andrew J Clifford
Stable isotope methods for the study of beta-carotene-d8 metabolism in humans utilizing tandem mass spectrometry and high-performance liquid chromatography.
Analytical chemistry 1994;66(23):4177-85.
1994: Teresa W-M Fan; Andrew J Clifford; R M Higashi
In vivo 13C NMR analysis of acyl chain composition and organization of perirenal triacylglycerides in rats fed vegetable and fish oils.
Journal of lipid research 1994;35(4):678-89.
1994: Susan E Ebeler; Steven H Hinrichs; Andrew J Clifford; Takayuki Shibamoto
Volatile carbonyl levels in tissues of transgenic mice with nerve sheath tumors.
Journal of chromatography. B, Biomedical applications 1994;654(1):9-18.
1993: Stephen R Dueker; Jennine M Lunetta; A Daniel Jones; Andrew J Clifford
Solid-phase extraction protocol for isolating retinol-d4 and retinol from plasma for parallel processing for epidemiological studies.
Clinical chemistry 1993;39(11 Pt 1):2318-22.
1993: G J Handelman; Marjorie J Haskell; A Daniel Jones; Andrew J Clifford
An improved protocol for determining ratios of retinol-d4 to retinol isolated from human plasma.
Analytical chemistry 1993;65(15):2024-8.
1993: Andrew J Clifford; N D Bills; Janet M Peerson; Hans-Georg Müller; G E Burk; K D Rich
A depletion-repletion folate bioassay based on growth and tissue folate concentrations of rats.
The Journal of nutrition 1993;123(5):926-32.
1992: Susan E Ebeler; Steven H Hinrichs; Andrew J Clifford; Takayuki Shibamoto
Analysis of reactive carbonyls in the expired air of transgenic mice.
Analytical biochemistry 1992;205(1):183-6.
1992: N D Bills; M J Koury; Andrew J Clifford; E N Dessypris
Ineffective hematopoiesis in folate-deficient mice.
Blood 1992;79(9):2273-80.
1992: M K Heid; N D Bills; Steven H Hinrichs; Andrew J Clifford
Folate deficiency alone does not produce neural tube defects in mice.
The Journal of nutrition 1992;122(4):888-94.
1992: N D Bills; Steven H Hinrichs; R Morgan; Andrew J Clifford
Delayed tumor onset in transgenic mice fed a low-folate diet.
Journal of the National Cancer Institute 1992;84(5):332-7.
1992: Harold C Furr; Andrew J Clifford; A D Jones
Analysis of apocarotenoids and retinoids by capillary gas chromatography-mass spectrometry.
Methods in enzymology 1992;213():281-90.
1991: N D Bills; A D Jones; Andrew J Clifford
Biological activity of racemic folate mixtures fed to folate-depleted rats.
The Journal of nutrition 1991;121(10):1643-8.
1991: Andrew J Clifford; M K Heid; Janet M Peerson; N D Bills
Bioavailability of food folates and evaluation of food matrix effects with a rat bioassay.
The Journal of nutrition 1991;121(4):445-53.
1991: L J Smidt; F M Cremin; Louis E Grivetti; Andrew J Clifford
Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
Journal of gerontology 1991;46(1):M16-22.
1990: Andrew J Clifford; A D Jones; N D Bills
Bioavailability of folates in selected foods incorporated into amino acid-based diets fed to rats.
The Journal of nutrition 1990;120(12):1640-7.
1990: Andrew J Clifford; M K Heid; Hans-Georg Müller; N D Bills
Tissue distribution and prediction of total body folate of rats.
The Journal of nutrition 1990;120(12):1633-9.
1990: L J Smidt; F M Cremin; Louis E Grivetti; Andrew J Clifford
Influence of folate status and polyphenol intake on thiamin status of Irish women.
The American journal of clinical nutrition 1990;52(6):1077-82.
1990: Harold C Furr; S H Zeng; Andrew J Clifford; James A Olson
Capillary gas chromatography of retinoids (vitamin A compounds) and apo-retinoids: determination of Kováts retention indices.
Journal of chromatography 1990;527(2):406-13.
1990: Andrew J Clifford; A D Jones; Harold C Furr
Stable isotope dilution mass spectrometry to assess vitamin A status.
Methods in enzymology 1990;189():94-104.
1989: Andrew J Clifford; D S Wilson; N D Bills
Repletion of folate-depleted rats with an amino acid-based diet supplemented with folic acid.
The Journal of nutrition 1989;119(12):1956-61.
1989: Harold C Furr; Andrew J Clifford; L M Smith; James A Olson
The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat.
The Journal of nutrition 1989;119(4):581-5.
1989: Harold C Furr; O Amedee-Manesme; Andrew J Clifford; H R Bergen; A D Jones; D P Anderson; James A Olson
Vitamin A concentrations in liver determined by isotope dilution assay with tetradeuterated vitamin A and by biopsy in generally healthy adult humans.
The American journal of clinical nutrition 1989;49(4):713-6.
1988: C R Smidt; A D Jones; Andrew J Clifford
Gas chromatography of retinol and alpha-tocopherol without derivatization.
Journal of chromatography 1988;434(1):21-9.
1988: Rosemary Walzem; Andrew J Clifford
Thiamin absorption is not compromised in folate-deficient rats.
The Journal of nutrition 1988;118(11):1343-8.
1988: Rosemary Walzem; Andrew J Clifford
Folate deficiency in rats fed diets containing free amino acids or intact proteins.
The Journal of nutrition 1988;118(9):1089-96.
1986: Andrew J Clifford; L M Smith; R K Creveling; C L Hamblin; C K Clifford
Effects of dietary triglycerides on serum and liver lipids and sterol excretion of rats.
The Journal of nutrition 1986;116(6):944-56.
1984: Y K Ho; D J Koehn; R J Sobieski; Andrew J Clifford; C K Clifford
Effects of purine amino groups on the development of Drosophila.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1984;79(2):435-9.
1983: Rosemary Walzem; C K Clifford; Andrew J Clifford
Purine synthesis and reutilization in folate-deficient rat hepatocytes.
The Journal of nutrition 1983;113(5):1032-8.
1983: C K Clifford; L M Smith; Kent L Erickson; C L Hamblin; R K Creveling; Andrew J Clifford
Effect of dietary triglycerides on lymphocyte transformation in rats.
The Journal of nutrition 1983;113(3):669-79.
1983: Rosemary Walzem; C K Clifford; Andrew J Clifford
Folate deficiency in rats fed amino acid diets.
The Journal of nutrition 1983;113(2):421-9.
1980: L B Neves; C K Clifford; G O Kohler; D de Fremery; B E Knuckles; C Cheowtirakul; M W Miller; W C Weir; Andrew J Clifford
Effects of dietary proteins from a variety of sources on plasma lipids and lipoproteins of rats.
The Journal of nutrition 1980;110(4):732-42.