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Marius Clore

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Nuclear Magnetic Resonance, Biomolecular

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Escherichia coli

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TOP 3
G Marius Clore
Generating accurate contact maps of transient long-range interactions in intrinsically disordered proteins by paramagnetic relaxation enhancement.
Guillermo A Bermejo; G Marius Clore; Charles D Schwieters
Smooth statistical torsion angle potential derived from a large conformational database via adaptive kernel density estimation improves the quality of NMR protein structures.
Alexander Grishaev; Nicholas J Anthis; G Marius Clore
Contrast-matched small-angle X-ray scattering from a heavy-atom-labeled protein in structure determination: application to a lead-substituted calmodulin-peptide complex.

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All Publications

2013: G Marius Clore
Generating accurate contact maps of transient long-range interactions in intrinsically disordered proteins by paramagnetic relaxation enhancement.
Biophysical journal 2013;104(8):1635-6.
2012: Guillermo A Bermejo; G Marius Clore; Charles D Schwieters
Smooth statistical torsion angle potential derived from a large conformational database via adaptive kernel density estimation improves the quality of NMR protein structures.
Protein science : a publication of the Protein Society 2012;21(12):1824-36.
2012: Alexander Grishaev; Nicholas J Anthis; G Marius Clore
Contrast-matched small-angle X-ray scattering from a heavy-atom-labeled protein in structure determination: application to a lead-substituted calmodulin-peptide complex.
Journal of the American Chemical Society 2012;134(36):14686-9.
2012: Vincenzo Venditti; G Marius Clore
Conformational selection and substrate binding regulate the monomer/dimer equilibrium of the C-terminal domain of Escherichia coli enzyme I.
The Journal of biological chemistry 2012;287(32):26989-98.
2012: Yuki Takayama; G Marius Clore
Impact of protein/protein interactions on global intermolecular translocation rates of the transcription factors Sox2 and Oct1 between DNA cognate sites analyzed by z-exchange NMR spectroscopy.
The Journal of biological chemistry 2012;287(32):26962-70.
2012: Nicolas L Fawzi; Dennis A Torchia; Jinfa Ying; G Marius Clore
Probing exchange kinetics and atomic resolution dynamics in high-molecular-weight complexes using dark-state exchange saturation transfer NMR spectroscopy.
Nature protocols 2012;7(8):1523-33.
2012: Young-Sang Jung; Mengli Cai; G Marius Clore
Solution structure of the IIAChitobiose-HPr complex of the N,N'-diacetylchitobiose branch of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2012;287(28):23819-29.
2012: Cajetan Dogo-Isonagie; Elena Gustchina; Peter D Kwong; Son Lam; Syed Shahzad-ul-Hussan; Yongping Yang; Priyamvada Acharya; G Marius Clore; Carole A Bewley
Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1.
The Journal of biological chemistry 2012;287(18):15076-86.
2012: Yuki Takayama; G Marius Clore
Interplay between minor and major groove-binding transcription factors Sox2 and Oct1 in translocation on DNA studied by paramagnetic and diamagnetic NMR.
The Journal of biological chemistry 2012;287(18):14349-63.
2012: Silvia A Arredondo; Mengli Cai; G Marius Clore; Nicholas J MacDonald; D Eric Anderson; L Aravind; Yuki Takayama; Louis H Miller
Structure of the Plasmodium 6-cysteine s48/45 domain.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(17):6692-7.
2012: Vincenzo Venditti; Nicolas L Fawzi; G Marius Clore
An efficient protocol for incorporation of an unnatural amino acid in perdeuterated recombinant proteins using glucose-based media.
Journal of biomolecular NMR 2012;52(3):191-5.
2012: Yaroslav Ryabov; G Marius Clore; Charles D Schwieters
Coupling between internal dynamics and rotational diffusion in the presence of exchange between discrete molecular conformations.
The Journal of chemical physics 2012;136(3):034108.
2011: Nicholas J Anthis; Michaeleen Doucleff; G Marius Clore
Transient, sparsely populated compact states of apo and calcium-loaded calmodulin probed by paramagnetic relaxation enhancement: interplay of conformational selection and induced fit.
Journal of the American Chemical Society 2011;133(46):18966-74.
2011: Vincenzo Venditti; Nicolas L Fawzi; G Marius Clore
Automated sequence- and stereo-specific assignment of methyl-labeled proteins by paramagnetic relaxation and methyl-methyl nuclear Overhauser enhancement spectroscopy.
Journal of biomolecular NMR 2011;51(3):319-28.
2011: Nicolas L Fawzi; Mark R Fleissner; Kálmán Hideg; Wayne L Hubbell; Tamás Kálai; Nicholas J Anthis; G Marius Clore
A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data.
Journal of biomolecular NMR 2011;51(1-2):105-14.
2011: Syed Shahzad-ul-Hussan; Elena Gustchina; Rodolfo Ghirlando; G Marius Clore; Carole A Bewley
Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
The Journal of biological chemistry 2011;286(23):20788-96.
2011: Yuki Takayama; G Marius Clore
Intra- and intermolecular translocation of the bi-domain transcription factor Oct1 characterized by liquid crystal and paramagnetic NMR.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(22):E169-76.
2011: Yaroslav Ryabov; Charles D Schwieters; G Marius Clore
Impact of 15N R2/R1 relaxation restraints on molecular size, shape, and bond vector orientation for NMR protein structure determination with sparse distance restraints.
Journal of the American Chemical Society 2011;133(16):6154-7.
2011: G Marius Clore
Exploring sparsely populated states of macromolecules by diamagnetic and paramagnetic NMR relaxation.
Protein science : a publication of the Protein Society 2011;20(2):229-46.
2011: Yuki Takayama; Rodolfo Ghirlando; Alexander Grishaev; Charles D Schwieters; G Marius Clore
Combined use of residual dipolar couplings and solution X-ray scattering to rapidly probe rigid-body conformational transitions in a non-phosphorylatable active-site mutant of the 128 kDa enzyme I dimer.
Journal of the American Chemical Society 2011;133(3):424-7.
2011: Ying Huang; Mengli Cai; G Marius Clore; Robert Craigie
No interaction of barrier-to-autointegration factor (BAF) with HIV-1 MA, cone-rod homeobox (Crx) or MAN1-C in absence of DNA.
PloS one 2011;6(9):e25123.
2010: Hao Yin; Guogang Feng; G Marius Clore; Gerhard Hummer; Jayendran C Rasaiah
Water in the polar and nonpolar cavities of the protein interleukin-1β.
The journal of physical chemistry. B 2010;114(49):16290-7.
2010: Junji Iwahara; G Marius Clore
Structure-independent analysis of the breadth of the positional distribution of disordered groups in macromolecules from order parameters for long, variable-length vectors using NMR paramagnetic relaxation enhancement.
Journal of the American Chemical Society 2010;132(38):13346-56.
2010: Charles D Schwieters; Jeong-Yong Suh; Alexander Grishaev; Rodolfo Ghirlando; Yuki Takayama; G Marius Clore
Solution structure of the 128 kDa enzyme I dimer from Escherichia coli and its 146 kDa complex with HPr using residual dipolar couplings and small- and wide-angle X-ray scattering.
Journal of the American Chemical Society 2010;132(37):13026-45.
2010: Nicolas L Fawzi; Jinfa Ying; Dennis A Torchia; G Marius Clore
Kinetics of amyloid beta monomer-to-oligomer exchange by NMR relaxation.
Journal of the American Chemical Society 2010;132(29):9948-51.
2010: Yaroslav Ryabov; G Marius Clore; Charles D Schwieters
Direct use of 15N relaxation rates as experimental restraints on molecular shape and orientation for docking of protein-protein complexes.
Journal of the American Chemical Society 2010;132(17):5987-9.
2010: Young-Sang Jung; Mengli Cai; G Marius Clore
Solution structure of the IIAChitobiose-IIBChitobiose complex of the N,N'-diacetylchitobiose branch of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2010;285(6):4173-84.
2010: Nicolas L Fawzi; Michaeleen Doucleff; Jeong-Yong Suh; G Marius Clore
Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1379-84.
2010: Mengli Cai; Ying Huang; Robert Craigie; G Marius Clore
Structural basis of the association of HIV-1 matrix protein with DNA.
PloS one 2010;5(12):e15675.
2010: Elena Gustchina; Mi Li; John M Louis; D Eric Anderson; John Lloyd; Christian Frisch; Carole A Bewley; Alla Gustchina; Alexander Wlodawer; G Marius Clore
Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.
PLoS pathogens 2010;6(11):e1001182.
2009: Elena Gustchina; John M Louis; Christian Frisch; Francisco Ylera; Annette Lechner; Carole A Bewley; G Marius Clore
Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.
Virology 2009;393(1):112-9.
2009: Kaifeng Hu; Michaeleen Doucleff; G Marius Clore
Using multiple quantum coherence to increase the 15N resolution in a three-dimensional TROSY HNCO experiment for accurate PRE and RDC measurements.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2009;200(2):173-7.
2009: G Marius Clore; Junji Iwahara
Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes.
Chemical reviews 2009;109(9):4108-39.
2009: Yaroslav Ryabov; Jeong-Yong Suh; Alexander Grishaev; G Marius Clore; Charles D Schwieters
Using the experimentally determined components of the overall rotational diffusion tensor to restrain molecular shape and size in NMR structure determination of globular proteins and protein-protein complexes.
Journal of the American Chemical Society 2009;131(27):9522-31.
2008: G Marius Clore
Visualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancement.
Molecular bioSystems 2008;4(11):1058-69.
2008: Chun Tang; John M Louis; Annie Aniana; Jeong-Yong Suh; G Marius Clore
Visualizing transient events in amino-terminal autoprocessing of HIV-1 protease.
Nature 2008;455(7213):693-6.
2008: Elena Gustchina; Carole A Bewley; G Marius Clore
Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41.
Journal of virology 2008;82(20):10032-41.
2008: Michaeleen Doucleff; G Marius Clore
Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13871-6.
2008: Young C Kim; Chun Tang; G Marius Clore; Gerhard Hummer
Replica exchange simulations of transient encounter complexes in protein-protein association.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):12855-60.
2008: John J Kuszewski; Robin Augustine Thottungal; G Marius Clore; Charles D Schwieters
Automated error-tolerant macromolecular structure determination from multidimensional nuclear Overhauser enhancement spectra and chemical shift assignments: improved robustness and performance of the PASD algorithm.
Journal of biomolecular NMR 2008;41(4):221-39.
2008: Josh D Nelson; Heather Kinkead; Florence Brunel; Dan Leaman; Richard Jensen; John M Louis; Toshiaki Maruyama; Carole A Bewley; Katherine Bowdish; G Marius Clore; Philip E Dawson; Shana Frederickson; Rose G Mage; Douglas D Richman; Dennis R Burton; Michael B Zwick
Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
Virology 2008;377(1):170-83.
2008: Jeong-Yong Suh; Mengli Cai; G Marius Clore
Impact of phosphorylation on structure and thermodynamics of the interaction between the N-terminal domain of enzyme I and the histidine phosphocarrier protein of the bacterial phosphotransferase system.
The Journal of biological chemistry 2008;283(27):18980-9.
2008: Charles D Schwieters; G Marius Clore
A pseudopotential for improving the packing of ellipsoidal protein structures determined from NMR data.
The journal of physical chemistry. B 2008;112(19):6070-3.
2008: Jun Hu; Kaifeng Hu; David C Williams; Michal E Komlosh; Mengli Cai; G Marius Clore
Solution NMR structures of productive and non-productive complexes between the A and B domains of the cytoplasmic subunit of the mannose transporter of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2008;283(16):11024-37.
2008: Chun Tang; Rodolfo Ghirlando; G Marius Clore
Visualization of transient ultra-weak protein self-association in solution using paramagnetic relaxation enhancement.
Journal of the American Chemical Society 2008;130(12):4048-56.
2007: Elena Gustchina; John M Louis; Son N Lam; Carole A Bewley; G Marius Clore
A monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains.
Journal of virology 2007;81(23):12946-53.
2007: Jeong-Yong Suh; Chun Tang; G Marius Clore
Role of electrostatic interactions in transient encounter complexes in protein-protein association investigated by paramagnetic relaxation enhancement.
Journal of the American Chemical Society 2007;129(43):12954-5.
2007: Debashish Sahu; G Marius Clore; Junji Iwahara
TROSY-based z-exchange spectroscopy: application to the determination of the activation energy for intermolecular protein translocation between specific sites on different DNA molecules.
Journal of the American Chemical Society 2007;129(43):13232-7.
2007: Chun Tang; Charles D Schwieters; G Marius Clore
Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR.
Nature 2007;449(7165):1078-82.
2007: G Marius Clore; Chun Tang; Junji Iwahara
Elucidating transient macromolecular interactions using paramagnetic relaxation enhancement.
Current opinion in structural biology 2007;17(5):603-16.
2007: Mengli Cai; Ying Huang; Jeong-Yong Suh; John M Louis; Rodolfo Ghirlando; Robert Craigie; G Marius Clore
Solution NMR structure of the barrier-to-autointegration factor-Emerin complex.
The Journal of biological chemistry 2007;282(19):14525-35.
2007: Kaifeng Hu; Beat Vögeli; G Marius Clore
Spin-state selective carbon-detected HNCO with TROSY optimization in all dimensions and double echo-antiecho sensitivity enhancement in both indirect dimensions.
Journal of the American Chemical Society 2007;129(17):5484-91.
2007: Junji Iwahara; Young-Sang Jung; G Marius Clore
Heteronuclear NMR spectroscopy for lysine NH(3) groups in proteins: unique effect of water exchange on (15)N transverse relaxation.
Journal of the American Chemical Society 2007;129(10):2971-80.
2007: Jeong-Yong Suh; Junji Iwahara; G Marius Clore
Intramolecular domain-domain association/dissociation and phosphoryl transfer in the mannitol transporter of Escherichia coli are not coupled.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3153-8.
2007: Charles D Schwieters; G Marius Clore
A physical picture of atomic motions within the Dickerson DNA dodecamer in solution derived from joint ensemble refinement against NMR and large-angle X-ray scattering data.
Biochemistry 2007;46(5):1152-66.
2006: Junji Iwahara; G Marius Clore
Sensitivity improvement for correlations involving arginine side-chain Nepsilon/Hepsilon resonances in multi-dimensional NMR experiments using broadband 15N 180 degrees pulses.
Journal of biomolecular NMR 2006;36(4):251-7.
2006: Kaifeng Hu; Beat Vögeli; G Marius Clore
13C-detected HN(CA)C and HMCMC experiments using a single methyl-reprotonated sample for unambiguous methyl resonance assignment.
Journal of biomolecular NMR 2006;36(4):259-66.
2006: Elena Gustchina; John M Louis; Carole A Bewley; G Marius Clore
Synergistic inhibition of HIV-1 envelope-mediated membrane fusion by inhibitors targeting the N and C-terminal heptad repeats of gp41.
Journal of molecular biology 2006;364(3):283-9.
2006: Chun Tang; Junji Iwahara; G Marius Clore
Visualization of transient encounter complexes in protein-protein association.
Nature 2006;444(7117):383-6.
2006: Junji Iwahara; Markus Zweckstetter; G Marius Clore
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(41):15062-7.
2006: Chun Tang; G Marius Clore
A simple and reliable approach to docking protein-protein complexes from very sparse NOE-derived intermolecular distance restraints.
Journal of biomolecular NMR 2006;36(1):37-44.
2006: Junji Iwahara; G Marius Clore
Detecting transient intermediates in macromolecular binding by paramagnetic NMR.
Nature 2006;440(7088):1227-30.
2006: Jeong-Yong Suh; Mengli Cai; David C Williams; G Marius Clore
Solution structure of a post-transition state analog of the phosphotransfer reaction between the A and B cytoplasmic domains of the mannitol transporter IIMannitol of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2006;281(13):8939-49.
2006: G Marius Clore; Charles D Schwieters
Concordance of residual dipolar couplings, backbone order parameters and crystallographic B-factors for a small alpha/beta protein: a unified picture of high probability, fast atomic motions in proteins.
Journal of molecular biology 2006;355(5):879-86.
2006: Junji Iwahara; G Marius Clore
Direct observation of enhanced translocation of a homeodomain between DNA cognate sites by NMR exchange spectroscopy.
Journal of the American Chemical Society 2006;128(2):404-5.
2005: Jeong-Yong Suh; Chun Tang; Mengli Cai; G Marius Clore
Visualization of the phosphorylated active site loop of the cytoplasmic B domain of the mannitol transporter II(Mannitol) of the Escherichia coli phosphotransferase system by NMR spectroscopy and residual dipolar couplings.
Journal of molecular biology 2005;353(5):1129-36.
2005: John M Louis; Carole A Bewley; Elena Gustchina; Annie Aniana; G Marius Clore
Characterization and HIV-1 fusion inhibitory properties of monoclonal Fabs obtained from a human non-immune phage library selected against diverse epitopes of the ectodomain of HIV-1 gp41.
Journal of molecular biology 2005;353(5):945-51.
2005: Chun Tang; Junji Iwahara; G Marius Clore
Accurate determination of leucine and valine side-chain conformations using U-[15N/13C/2H]/[1H-(methine/methyl)-Leu/Val] isotope labeling, NOE pattern recognition, and methine Cgamma-Hgamma/Cbeta-Hbeta residual dipolar couplings: application to the 34-kDa enzyme IIA(chitobiose).
Journal of biomolecular NMR 2005;33(2):105-21.
2005: Antony S Dimitrov; John M Louis; Carole A Bewley; G Marius Clore; Robert Blumenthal
Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation.
Biochemistry 2005;44(37):12471-9.
2005: David C Williams; Jae Young Lee; Mengli Cai; Carole A Bewley; G Marius Clore
Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to Man3GlcNAc2: structural basis for specificity and high-affinity binding to the core pentasaccharide from n-linked oligomannoside.
The Journal of biological chemistry 2005;280(32):29269-76.
2005: David C Williams; Mengli Cai; Jeong-Yong Suh; Alan Peterkofsky; G Marius Clore
Solution NMR structure of the 48-kDa IIAMannose-HPr complex of the Escherichia coli mannose phosphotransferase system.
The Journal of biological chemistry 2005;280(21):20775-84.
2005: Elena Gustchina; Gerhard Hummer; Carole A Bewley; G Marius Clore
Differential inhibition of HIV-1 and SIV envelope-mediated cell fusion by C34 peptides derived from the C-terminal heptad repeat of gp41 from diverse strains of HIV-1, HIV-2, and SIV.
Journal of medicinal chemistry 2005;48(8):3036-44.
2005: Chun Tang; David C Williams; Rodolfo Ghirlando; G Marius Clore
Solution structure of enzyme IIA(Chitobiose) from the N,N'-diacetylchitobiose branch of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2005;280(12):11770-80.
2005: Elliott Gozansky; John M Louis; Michael Caffrey; G Marius Clore
Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha.
Journal of molecular biology 2005;345(4):651-8.
2004: Junji Iwahara; Charles D Schwieters; G Marius Clore
Characterization of nonspecific protein-DNA interactions by 1H paramagnetic relaxation enhancement.
Journal of the American Chemical Society 2004;126(40):12800-8.
2004: Jeffrey R Huth; Liping Yu; Irene Collins; Jamey Mack; Renaldo Mendoza; Binumol Isaac; Demetrios T Braddock; Steven W Muchmore; Kenneth M Comess; Stephen W Fesik; G Marius Clore; David Levens; Philip J Hajduk
NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.
Journal of medicinal chemistry 2004;47(20):4851-7.
2004: Patricia M Legler; Mengli Cai; Alan Peterkofsky; G Marius Clore
Three-dimensional solution structure of the cytoplasmic B domain of the mannitol transporter IImannitol of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2004;279(37):39115-21.
2004: Emeric Miclet; David C Williams Jr; G Marius Clore; David L Bryce; Jérôme Boisbouvier; Adriaan Bax
Relaxation-optimized NMR spectroscopy of methylene groups in proteins and nucleic acids.
Journal of the American Chemical Society 2004;126(34):10560-70.
2004: G Marius Clore; Charles D Schwieters
Amplitudes of protein backbone dynamics and correlated motions in a small alpha/beta protein: correspondence of dipolar coupling and heteronuclear relaxation measurements.
Biochemistry 2004;43(33):10678-91.
2004: Stephen A Gallo; G Marius Clore; John M Louis; Carole A Bewley; Robert Blumenthal
Temperature-dependent intermediates in HIV-1 envelope glycoprotein-mediated fusion revealed by inhibitors that target N- and C-terminal helical regions of HIV-1 gp41.
Biochemistry 2004;43(25):8230-3.
2004: John Kuszewski; Charles D Schwieters; Daniel S Garrett; R Andrew Byrd; Nico Tjandra; G Marius Clore
Completely automated, highly error-tolerant macromolecular structure determination from multidimensional nuclear overhauser enhancement spectra and chemical shift assignments.
Journal of the American Chemical Society 2004;126(20):6258-73.
2004: Junji Iwahara; Charles D Schwieters; G Marius Clore
Ensemble approach for NMR structure refinement against (1)H paramagnetic relaxation enhancement data arising from a flexible paramagnetic group attached to a macromolecule.
Journal of the American Chemical Society 2004;126(18):5879-96.
2004: Daniela M Schulz; Christian Ihling; G Marius Clore; Andrea Sinz
Mapping the topology and determination of a low-resolution three-dimensional structure of the calmodulin-melittin complex by chemical cross-linking and high-resolution FTICRMS: direct demonstration of multiple binding modes.
Biochemistry 2004;43(16):4703-15.
2004: G Marius Clore; Charles D Schwieters
How much backbone motion in ubiquitin is required to account for dipolar coupling data measured in multiple alignment media as assessed by independent cross-validation?
Journal of the American Chemical Society 2004;126(9):2923-38.
2004: David C Williams; Mengli Cai; G Marius Clore
Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
The Journal of biological chemistry 2004;279(2):1449-57.
2003: Mengli Cai; David C Williams; Guangshun Wang; Byeong Ryong Lee; Alan Peterkofsky; G Marius Clore
Solution structure of the phosphoryl transfer complex between the signal-transducing protein IIAGlucose and the cytoplasmic domain of the glucose transporter IICBGlucose of the Escherichia coli glucose phosphotransferase system.
The Journal of biological chemistry 2003;278(27):25191-206.
2003: Junji Iwahara; D Eric Anderson; Elizabeth C Murphy; G Marius Clore
EDTA-derivatized deoxythymidine as a tool for rapid determination of protein binding polarity to DNA by intermolecular paramagnetic relaxation enhancement.
Journal of the American Chemical Society 2003;125(22):6634-5.
2003: John M Louis; Issa Nesheiwat; LengChee Chang; G Marius Clore; Carole A Bewley
Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.
The Journal of biological chemistry 2003;278(22):20278-85.
2003: G Marius Clore; Charles D Schwieters
Docking of protein-protein complexes on the basis of highly ambiguous intermolecular distance restraints derived from 1H/15N chemical shift mapping and backbone 15N-1H residual dipolar couplings using conjoined rigid body/torsion angle dynamics.
Journal of the American Chemical Society 2003;125(10):2902-12.
2003: G Marius Clore; John Kuszewski
Improving the accuracy of NMR structures of RNA by means of conformational database potentials of mean force as assessed by complete dipolar coupling cross-validation.
Journal of the American Chemical Society 2003;125(6):1518-25.
2003: Charles D Schwieters; John J Kuszewski; Nico Tjandra; G Marius Clore
The Xplor-NIH NMR molecular structure determination package.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;160(1):65-73.
2002: Gabriel Cornilescu; Byeong Ryong Lee; Claudia C Cornilescu; Guangshun Wang; Alan Peterkofsky; G Marius Clore
Solution structure of the phosphoryl transfer complex between the cytoplasmic A domain of the mannitol transporter IIMannitol and HPr of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2002;277(44):42289-98.
2002: Charles D Schwieters; G Marius Clore
Reweighted atomic densities to represent ensembles of NMR structures.
Journal of biomolecular NMR 2002;23(3):221-5.
2002: Demetrios T Braddock; James L Baber; David Levens; G Marius Clore
Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.
The EMBO journal 2002;21(13):3476-85.
2002: Carole A Bewley; John M Louis; Rodolfo Ghirlando; G Marius Clore
Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.
The Journal of biological chemistry 2002;277(16):14238-45.
2002: G Marius Clore; Charles D Schwieters
Theoretical and computational advances in biomolecular NMR spectroscopy.
Current opinion in structural biology 2002;12(2):146-53.
2002: G Marius Clore; John Kuszewski
Chi(1) rotamer populations and angles of mobile surface side chains are accurately predicted by a torsion angle database potential of mean force.
Journal of the American Chemical Society 2002;124(12):2866-7.
2002: Demetrios T Braddock; John M Louis; James L Baber; David Levens; G Marius Clore
Structure and dynamics of KH domains from FBP bound to single-stranded DNA.
Nature 2002;415(6875):1051-6.
2002: G Marius Clore; Carole A Bewley
Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;154(2):329-35.
2001: Charles D Schwieters; G Marius Clore
Internal coordinates for molecular dynamics and minimization in structure determination and refinement.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;152(2):288-302.
2001: Elizabeth C Murphy; Victor B Zhurkin; John M Louis; Gabriel Cornilescu; G Marius Clore
Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation.
Journal of molecular biology 2001;312(3):481-99.
2001: M Cai; Y Huang; G Marius Clore
Accurate orientation of the functional groups of asparagine and glutamine side chains using one- and two-bond dipolar couplings.
Journal of the American Chemical Society 2001;123(35):8642-3.
2001: Demetrios T Braddock; M Cai; James L Baber; Y Huang; G Marius Clore
Rapid identification of medium- to large-scale interdomain motion in modular proteins using dipolar couplings.
Journal of the American Chemical Society 2001;123(35):8634-5.
2001: Mengli Cai; Ying Huang; Rodolfo Ghirlando; Katherine L Wilson; Robert Craigie; G Marius Clore
Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
The EMBO journal 2001;20(16):4399-407.
2001: John M Louis; Carole A Bewley; G Marius Clore
Design and properties of N(CCG)-gp41, a chimeric gp41 molecule with nanomolar HIV fusion inhibitory activity.
The Journal of biological chemistry 2001;276(31):29485-9.
2001: Alan Peterkofsky; Guangshun Wang; Daniel S Garrett; B R Lee; Yeong-Jae Seok; G Marius Clore
Three-dimensional structures of protein-protein complexes in the E. coli PTS.
Journal of molecular microbiology and biotechnology 2001;3(3):347-54.
2001: John Kuszewski; Charles D Schwieters; G Marius Clore
Improving the accuracy of NMR structures of DNA by means of a database potential of mean force describing base-base positional interactions.
Journal of the American Chemical Society 2001;123(17):3903-18.
2001: Charles D Schwieters; G Marius Clore
The VMD-XPLOR visualization package for NMR structure refinement.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;149(2):239-44.
2000: Guangshun Wang; Alan Peterkofsky; G Marius Clore
A novel membrane anchor function for the N-terminal amphipathic sequence of the signal-transducing protein IIAGlucose of the Escherichia coli phosphotransferase system.
The Journal of biological chemistry 2000;275(51):39811-4.
2000: Guangshun Wang; J M Louis; Melissa Sondej; Yeong-Jae Seok; Alan Peterkofsky; G Marius Clore
Solution structure of the phosphoryl transfer complex between the signal transducing proteins HPr and IIA(glucose) of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.
The EMBO journal 2000;19(21):5635-49.
2000: John Kuszewski; G Marius Clore
Sources of and solutions to problems in the refinement of protein NMR structures against torsion angle potentials of mean force.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;146(2):249-54.
2000: G Marius Clore
Accurate and rapid docking of protein-protein complexes on the basis of intermolecular nuclear overhauser enhancement data and dipolar couplings by rigid body minimization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9021-5.
2000: Michael Caffrey; Demetrios T Braddock; John M Louis; M A Abu-Asab; D Kingma; Lance A Liotta; M Tsokos; N Tresser; Lewis K Pannell; N Watts; Alasdair C Steven; Martha N Simon; Stephen J Stahl; Paul T Wingfield; G Marius Clore
Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia.
The Journal of biological chemistry 2000;275(26):19877-82.
2000: Guangshun Wang; Melissa Sondej; Daniel S Garrett; Alan Peterkofsky; G Marius Clore
A common interface on histidine-containing phosphocarrier protein for interaction with its partner proteins.
The Journal of biological chemistry 2000;275(22):16401-3.
2000: K Huang; J M Louis; L Donaldson; Fei Ling Lim; Andrew D Sharrocks; G Marius Clore
Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors.
The EMBO journal 2000;19(11):2615-28.
2000: G Kontaxis; G Marius Clore; Adriaan Bax
Evaluation of cross-correlation effects and measurement of one-bond couplings in proteins with short transverse relaxation times.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;143(1):184-96.
2000: Nico Tjandra; J Marquardt; G Marius Clore
Direct refinement against proton-proton dipolar couplings in NMR structure determination of macromolecules.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;142(2):393-6.
2000: John M Louis; Irene T Weber; József Tözsér; G Marius Clore; Angela M Gronenborn
HIV-1 protease: maturation, enzyme specificity, and drug resistance.
Advances in pharmacology (San Diego, Calif.) 2000;49():111-46.
1999: Michael Caffrey; J Kaufman; S Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
Monomer-trimer equilibrium of the ectodomain of SIV gp41: insight into the mechanism of peptide inhibition of HIV infection.
Protein science : a publication of the Protein Society 1999;8(9):1904-7.
1999: John M Louis; G Marius Clore; Angela M Gronenborn
Autoprocessing of HIV-1 protease is tightly coupled to protein folding.
Nature structural biology 1999;6(9):868-75.
1999: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; Angela M Gronenborn; G Marius Clore
Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nature structural biology 1999;6(2):166-73.
1999: Angela M Gronenborn; G Marius Clore; John M Louis; Paul T Wingfield
Is human thioredoxin monomeric or dimeric?
Protein science : a publication of the Protein Society 1999;8(2):426-9.
1998: Michael Caffrey; J Kaufman; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
3D NMR experiments for measuring 15N relaxation data of large proteins: application to the 44 kDa ectodomain of SIV gp41.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;135(2):368-72.
1998: Mengli Cai; Y Huang; Michael Caffrey; R Zheng; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium.
Protein science : a publication of the Protein Society 1998;7(12):2669-74.
1998: G Marius Clore; Angela M Gronenborn
NMR structure determination of proteins and protein complexes larger than 20 kDa.
Current opinion in chemical biology 1998;2(5):564-70.
1998: Mengli Cai; Y Huang; R Zheng; SQ Wei; Rodolfo Ghirlando; MS Lee; Robert Craigie; Angela M Gronenborn; G Marius Clore
Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration.
Nature structural biology 1998;5(10):903-9.
1998: G Marius Clore; Elizabeth C Murphy; Angela M Gronenborn; Adriaan Bax
Determination of three-bond 1H3'-31P couplings in nucleic acids and protein-nucleic acid complexes by quantitative J correlation spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;134(1):164-7.
1998: Michael Caffrey; Mengli Cai; J Kaufman; Stephen J Stahl; Paul T Wingfield; D G Covell; Angela M Gronenborn; G Marius Clore
Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41.
The EMBO journal 1998;17(16):4572-84.
1998: Carole A Bewley; K R Gustafson; M R Boyd; D G Covell; Adriaan Bax; G Marius Clore; Angela M Gronenborn
Solution structure of cyanovirin-N, a potent HIV-inactivating protein.
Nature structural biology 1998;5(7):571-8.
1998: G Marius Clore; Angela M Gronenborn; Adriaan Bax
A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural information.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;133(1):216-21.
1998: G Marius Clore; Angela M Gronenborn
New methods of structure refinement for macromolecular structure determination by NMR.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):5891-8.
1998: M R Starich; M Wikström; S Schumacher; H N Arst; Angela M Gronenborn; G Marius Clore
The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
Journal of molecular biology 1998;277(3):621-34.
1998: M R Starich; M Wikström; H N Arst; G Marius Clore; Angela M Gronenborn
The solution structure of a fungal AREA protein-DNA complex: an alternative binding mode for the basic carboxyl tail of GATA factors.
Journal of molecular biology 1998;277(3):605-20.
1998: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; G Marius Clore; Angela M Gronenborn
Tautomeric state and pKa of the phosphorylated active site histidine in the N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.
Protein science : a publication of the Protein Society 1998;7(3):789-93.
1998: G Marius Clore; Angela M Gronenborn; Nico Tjandra
Direct structure refinement against residual dipolar couplings in the presence of rhombicity of unknown magnitude.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;131(1):159-62.
1998: John M Louis; Robert G Martin; G Marius Clore; Angela M Gronenborn
Preparation of uniformly isotope-labeled DNA oligonucleotides for NMR spectroscopy.
The Journal of biological chemistry 1998;273(4):2374-8.
1998: Carole A Bewley; Angela M Gronenborn; G Marius Clore
Minor groove-binding architectural proteins: structure, function, and DNA recognition.
Annual review of biophysics and biomolecular structure 1998;27():105-31.
1998: Mengli Cai; Y Huang; K Sakaguchi; G Marius Clore; Angela M Gronenborn; Robert Craigie
An efficient and cost-effective isotope labeling protocol for proteins expressed in Escherichia coli.
Journal of biomolecular NMR 1998;11(1):97-102.
1997: S Schumacher; R T Clubb; Mengli Cai; Kiyoshi Mizuuchi; G Marius Clore; Angela M Gronenborn
Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.
The EMBO journal 1997;16(24):7532-41.
1997: J R Huth; Carole A Bewley; B M Jackson; A G Hinnebusch; G Marius Clore; Angela M Gronenborn
Design of an expression system for detecting folded protein domains and mapping macromolecular interactions by NMR.
Protein science : a publication of the Protein Society 1997;6(11):2359-64.
1997: R T Clubb; S Schumacher; Kiyoshi Mizuuchi; Angela M Gronenborn; G Marius Clore
Solution structure of the I gamma subdomain of the Mu end DNA-binding domain of phage Mu transposase.
Journal of molecular biology 1997;273(1):19-25.
1997: G Marius Clore; Angela M Gronenborn
NMR structures of proteins and protein complexes beyond 20,000 M(r).
Nature structural biology 1997;4 Suppl():849-53.
1997: Michael Caffrey; Mengli Cai; J Kaufman; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn; G Marius Clore
Determination of the secondary structure and global topology of the 44 kDa ectodomain of gp41 of the simian immunodeficiency virus by multidimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1997;271(5):819-26.
1997: Nico Tjandra; James G. Omichinski; Angela M Gronenborn; G Marius Clore; Adriaan Bax
Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution.
Nature structural biology 1997;4(9):732-8.
1997: J R Huth; Carole A Bewley; MS Nissen; Jeremy N S Evans; Raymond Reeves; Angela M Gronenborn; G Marius Clore
The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.
Nature structural biology 1997;4(8):657-65.
1997: Mengli Cai; R Zheng; Michael Caffrey; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase.
Nature structural biology 1997;4(7):567-77.
1997: Akhilesh K Nagaich; Victor B Zhurkin; H Sakamoto; Andrey A Gorin; G Marius Clore; A M Gronenborn; Ettore Appella; Rodney E Harrington
Architectural accommodation in the complex of four p53 DNA binding domain peptides with the p21/waf1/cip1 DNA response element.
The Journal of biological chemistry 1997;272(23):14830-41.
1997: Nico Tjandra; Daniel S Garrett; Angela M Gronenborn; Adriaan Bax; G Marius Clore
Defining long range order in NMR structure determination from the dependence of heteronuclear relaxation times on rotational diffusion anisotropy.
Nature structural biology 1997;4(6):443-9.
1997: Paolo V Pedone; James G. Omichinski; P Nony; Cecelia D Trainor; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
The N-terminal fingers of chicken GATA-2 and GATA-3 are independent sequence-specific DNA binding domains.
The EMBO journal 1997;16(10):2874-82.
1997: Daniel S Garrett; Yeong-Jae Seok; Alan Peterkofsky; G Marius Clore; Angela M Gronenborn
Identification by NMR of the binding surface for the histidine-containing phosphocarrier protein HPr on the N-terminal domain of enzyme I of the Escherichia coli phosphotransferase system.
Biochemistry 1997;36(15):4393-8.
1997: Daniel S Garrett; Yeong-Jae Seok; D I Liao; Alan Peterkofsky; Angela M Gronenborn; G Marius Clore
Solution structure of the 30 kDa N-terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system by multidimensional NMR.
Biochemistry 1997;36(9):2517-30.
1997: John Kuszewski; Angela M Gronenborn; G Marius Clore
Improvements and extensions in the conformational database potential for the refinement of NMR and X-ray structures of proteins and nucleic acids.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;125(1):171-7.
1997: James G. Omichinski; Paolo V Pedone; Gary Felsenfeld; Angela M Gronenborn; G Marius Clore
The solution structure of a specific GAGA factor-DNA complex reveals a modular binding mode.
Nature structural biology 1997;4(2):122-32.
1997: G Marius Clore; Angela M Gronenborn
Dissecting intrinsic chaperonin activity.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):7-8.
1996: Angela M Gronenborn; M K Frank; G Marius Clore
Core mutants of the immunoglobulin binding domain of streptococcal protein G: stability and structural integrity.
FEBS letters 1996;398(2-3):312-6.
1996: Milton H Werner; J R Huth; Angela M Gronenborn; G Marius Clore
Molecular determinants of mammmalian sex.
Trends in biochemical sciences 1996;21(8):302-8.
1996: J Kuszewski; Angela M Gronenborn; G Marius Clore
A potential involving multiple proton chemical-shift restraints for nonstereospecifically assigned methyl and methylene protons.
Journal of magnetic resonance. Series B 1996;112(1):79-81.
1996: J Kuszewski; Angela M Gronenborn; G Marius Clore
Improving the quality of NMR and crystallographic protein structures by means of a conformational database potential derived from structure databases.
Protein science : a publication of the Protein Society 1996;5(6):1067-80.
1996: J Qin; G Marius Clore; W P Kennedy; J Kuszewski; Angela M Gronenborn
The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure (London, England : 1993) 1996;4(5):613-20.
1996: C D Trainor; James G. Omichinski; T L Vandergon; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction.
Molecular and cellular biology 1996;16(5):2238-47.
1996: Paolo V Pedone; R Ghirlando; G Marius Clore; Angela M Gronenborn; Gary Felsenfeld; James G. Omichinski
The single Cys2-His2 zinc finger domain of the GAGA protein flanked by basic residues is sufficient for high-affinity specific DNA binding.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2822-6.
1996: Stephan Grzesiek; Adriaan Bax; G Marius Clore; Angela M Gronenborn; Jin-Shan Hu; J Kaufman; I Palmer; Stephen J Stahl; Paul T Wingfield
The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase.
Nature structural biology 1996;3(4):340-5.
1996: Milton H Werner; Angela M Gronenborn; G Marius Clore
Intercalation, DNA kinking, and the control of transcription.
Science (New York, N.Y.) 1996;271(5250):778-84.
1996: R T Clubb; M Mizuuchi; J R Huth; James G. Omichinski; H Savilahti; Kiyoshi Mizuuchi; G Marius Clore; Angela M Gronenborn
The wing of the enhancer-binding domain of Mu phage transposase is flexible and is essential for efficient transposition.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1146-50.
1996: J Qin; G Marius Clore; Angela M Gronenborn
Ionization equilibria for side-chain carboxyl groups in oxidized and reduced human thioredoxin and in the complex with its target peptide from the transcription factor NF kappa B.
Biochemistry 1996;35(1):7-13.
1996: Angela M Gronenborn; G Marius Clore
Rapid screening for structural integrity of expressed proteins by heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1996;5(1):174-7.
1995: M K Frank; G Marius Clore; Angela M Gronenborn
Structural and dynamic characterization of the urea denatured state of the immunoglobulin binding domain of streptococcal protein G by multidimensional heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1995;4(12):2605-15.
1995: T E Strzelecka; G Marius Clore; Angela M Gronenborn
The solution structure of the Mu Ner protein reveals a helix-turn-helix DNA recognition motif.
Structure (London, England : 1993) 1995;3(10):1087-95.
1995: Milton H Werner; M E Bianchi; Angela M Gronenborn; G Marius Clore
NMR spectroscopic analysis of the DNA conformation induced by the human testis determining factor SRY.
Biochemistry 1995;34(37):11998-2004.
1995: P J Lodi; J A Ernst; J Kuszewski; Alison Burgess Hickman; Alan Engelman; Robert Craigie; G Marius Clore; Angela M Gronenborn
Solution structure of the DNA binding domain of HIV-1 integrase.
Biochemistry 1995;34(31):9826-33.
1995: Milton H Werner; J R Huth; Angela M Gronenborn; G Marius Clore
Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex.
Cell 1995;81(5):705-14.
1995: J Kuszewski; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against proton chemical shifts on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1995;107(3):293-7.
1995: R T Clubb; James G. Omichinski; K Sakaguchi; Ettore Appella; Angela M Gronenborn; G Marius Clore
Backbone dynamics of the oligomerization domain of p53 determined from 15N NMR relaxation measurements.
Protein science : a publication of the Protein Society 1995;4(5):855-62.
1995: G Marius Clore; J Ernst; R Clubb; James G. Omichinski; W M Kennedy; K Sakaguchi; Ettore Appella; Angela M Gronenborn
Refined solution structure of the oligomerization domain of the tumour suppressor p53.
Nature structural biology 1995;2(4):321-33.
1995: J A Ernst; R T Clubb; Huan-Xiang Zhou; Angela M Gronenborn; G Marius Clore
Demonstration of positionally disordered water within a protein hydrophobic cavity by NMR.
Science (New York, N.Y.) 1995;267(5205):1813-7.
1995: J Qin; G Marius Clore; W M Kennedy; J R Huth; Angela M Gronenborn
Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure (London, England : 1993) 1995;3(3):289-97.
1995: G Marius Clore; James G. Omichinski; Kazuyasu Sakaguchi; N Zambrano; H Sakamoto; Ettore Appella; Angela M Gronenborn
Interhelical angles in the solution structure of the oligomerization domain of p53: correction.
Science (New York, N.Y.) 1995;267(5203):1515-6.
1995: T E Strzelecka; Jeffrey J Hayes; G Marius Clore; Angela M Gronenborn
DNA binding specificity of the Mu Ner protein.
Biochemistry 1995;34(9):2946-55.
1995: J Kuszewski; J Qin; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against 13C alpha and 13C beta chemical shifts on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1995;106(1):92-6.
1995: G Marius Clore; Angela M Gronenborn
Three-dimensional structures of alpha and beta chemokines.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(1):57-62.
1994: R T Clubb; James G. Omichinski; H Savilahti; Kiyoshi Mizuuchi; Angela M Gronenborn; G Marius Clore
A novel class of winged helix-turn-helix protein: the DNA-binding domain of Mu transposase.
Structure (London, England : 1993) 1994;2(11):1041-8.
1994: J Kuszewski; G Marius Clore; Angela M Gronenborn
Fast folding of a prototypic polypeptide: the immunoglobulin binding domain of streptococcal protein G.
Protein science : a publication of the Protein Society 1994;3(11):1945-52.
1994: A C Wang; P J Lodi; J Qin; Geerten W Vuister; Angela M Gronenborn; G Marius Clore
An efficient triple-resonance experiment for proton-directed sequential backbone assignment of medium-sized proteins.
Journal of magnetic resonance. Series B 1994;105(2):196-8.
1994: G Marius Clore; James G. Omichinski; Kazuyasu Sakaguchi; N Zambrano; H Sakamoto; Ettore Appella; Angela M Gronenborn
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Science (New York, N.Y.) 1994;265(5170):386-91.
1994: B L Grasberger; G Marius Clore; Angela M Gronenborn
High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site.
Structure (London, England : 1993) 1994;2(7):669-78.
1994: J Qin; G Marius Clore; Angela M Gronenborn
The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure (London, England : 1993) 1994;2(6):503-22.
1994: Milton H Werner; G Marius Clore; Angela M Gronenborn; Howard A Nash
Symmetry and asymmetry in the function of Escherichia coli integration host factor: implications for target identification by DNA-binding proteins.
Current biology : CB 1994;4(6):477-87.
1994: Milton H Werner; G Marius Clore; Angela M Gronenborn; A Kondoh; Robert J Fisher
Refolding proteins by gel filtration chromatography.
FEBS letters 1994;345(2-3):125-30.
1994: Daniel S Garrett; J Kuszewski; T J Hancock; P J Lodi; Geerten W Vuister; Angela M Gronenborn; G Marius Clore
The impact of direct refinement against three-bond HN-C alpha H coupling constants on protein structure determination by NMR.
Journal of magnetic resonance. Series B 1994;104(1):99-103.
1994: Angela M Gronenborn; G Marius Clore
Identification of N-terminal helix capping boxes by means of 13C chemical shifts.
Journal of biomolecular NMR 1994;4(3):455-8.
1994: P J Lodi; Daniel S Garrett; J Kuszewski; M L Tsang; J A Weatherbee; Warren J Leonard; Angela M Gronenborn; G Marius Clore
High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.
Science (New York, N.Y.) 1994;263(5154):1762-7.
1994: Daniel S Garrett; P J Lodi; Yousif Shamoo; K R Williams; G Marius Clore; Angela M Gronenborn
Determination of the secondary structure and folding topology of an RNA binding domain of mammalian hnRNP A1 protein using three-dimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1994;33(10):2852-8.
1994: G Marius Clore; Angela M Gronenborn
Young Investigator Award Lecture. Structures of larger proteins, protein-ligand and protein-DNA complexes by multidimensional heteronuclear NMR.
Protein science : a publication of the Protein Society 1994;3(3):372-90.
1994: G Marius Clore; Adriaan Bax; James G. Omichinski; Angela M Gronenborn
Localization of bound water in the solution structure of a complex of the erythroid transcription factor GATA-1 with DNA.
Structure (London, England : 1993) 1994;2(2):89-94.
1994: R T Clubb; James G. Omichinski; G Marius Clore; Angela M Gronenborn
Mapping the binding surface of interleukin-8 complexed with an N-terminal fragment of the type 1 human interleukin-8 receptor.
FEBS letters 1994;338(1):93-7.
1994: Joseph J Barchi; B Grasberger; Angela M Gronenborn; G Marius Clore
Investigation of the backbone dynamics of the IgG-binding domain of streptococcal protein G by heteronuclear two-dimensional 1H-15N nuclear magnetic resonance spectroscopy.
Protein science : a publication of the Protein Society 1994;3(1):15-21.
1994: G Marius Clore; Angela M Gronenborn
Structures of larger proteins, protein-ligand and protein-DNA complexes by multi-dimensional heteronuclear NMR.
Progress in biophysics and molecular biology 1994;62(2):153-84.
1993: Angela M Gronenborn; G Marius Clore
Identification of the contact surface of a streptococcal protein G domain complexed with a human Fc fragment.
Journal of molecular biology 1993;233(3):331-5.
1993: James G. Omichinski; G Marius Clore; O Schaad; Gary Felsenfeld; C Trainor; Ettore Appella; S J Stahl; Angela M Gronenborn
NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
Science (New York, N.Y.) 1993;261(5120):438-46.
1993: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1993;32(26):6744-62.
1993: Kazuyasu Sakaguchi; N Zambrano; Eric Baldwin; B A Shapiro; J W Erickson; James G. Omichinski; G Marius Clore; Angela M Gronenborn; Ettore Appella
Identification of a binding site for the human immunodeficiency virus type 1 nucleocapsid protein.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5219-23.
1993: Paul Varley; Angela M Gronenborn; H Christensen; Paul T Wingfield; R H Pain; G Marius Clore
Kinetics of folding of the all-beta sheet protein interleukin-1 beta.
Science (New York, N.Y.) 1993;260(5111):1110-3.
1993: G Marius Clore; M A Robien; Angela M Gronenborn
Exploring the limits of precision and accuracy of protein structures determined by nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1993;231(1):82-102.
1993: B L Grasberger; Angela M Gronenborn; G Marius Clore
Analysis of the backbone dynamics of interleukin-8 by 15N relaxation measurements.
Journal of molecular biology 1993;230(2):364-72.
1993: James G. Omichinski; C Trainor; T Evans; Angela M Gronenborn; G Marius Clore; Gary Felsenfeld
A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1676-80.
1992: A Achari; S P Hale; A J Howard; G Marius Clore; Angela M Gronenborn; K D Hardman; M Whitlow
1.67-A X-ray structure of the B2 immunoglobulin-binding domain of streptococcal protein G and comparison to the NMR structure of the B1 domain.
Biochemistry 1992;31(43):10449-57.
1992: Robert Powers; G Marius Clore; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn
Analysis of the backbone dynamics of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase using 15N relaxation measurements.
Biochemistry 1992;31(38):9150-7.
1992: Julie D Forman-Kay; G Marius Clore; Stephen J Stahl; Angela M Gronenborn
1H and 15N resonance assignments and secondary structure of the human thioredoxin C62A, C69A, C73A mutant.
Journal of biomolecular NMR 1992;2(5):431-45.
1992: B Shaanan; Angela M Gronenborn; G H Cohen; Gary L Gilliland; B Veerapandian; David Davies; G Marius Clore
Combining experimental information from crystal and solution studies: joint X-ray and NMR refinement.
Science (New York, N.Y.) 1992;257(5072):961-4.
1992: I Chandrasekhar; G Marius Clore; A Szabo; Angela M Gronenborn; Bernard Brooks
A 500 ps molecular dynamics simulation study of interleukin-1 beta in water. Correlation with nuclear magnetic resonance spectroscopy and crystallography.
Journal of molecular biology 1992;226(1):239-50.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy.
Science (New York, N.Y.) 1992;256(5064):1673-7.
1992: Daniel S Garrett; Robert Powers; CJ March; E A Frieden; G Marius Clore; Angela M Gronenborn
Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4347-53.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
1H, 15N, 13C, and 13CO assignments of human interleukin-4 using three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4334-46.
1992: M Ikura; G Marius Clore; Angela M Gronenborn; G Zhu; C B Klee; Adriaan Bax
Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science (New York, N.Y.) 1992;256(5057):632-8.
1992: James G. Omichinski; G Marius Clore; M Robien; Kazuyasu Sakaguchi; Ettore Appella; Angela M Gronenborn
High-resolution solution structure of the double Cys2His2 zinc finger from the human enhancer binding protein MBP-1.
Biochemistry 1992;31(16):3907-17.
1992: R H Lozier; A Xie; James Hofrichter; G Marius Clore
Reversible steps in the bacteriorhodopsin photocycle.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3610-4.
1992: M A Robien; G Marius Clore; James G. Omichinski; R N Perham; Ettore Appella; Kazuyasu Sakaguchi; Angela M Gronenborn
Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli.
Biochemistry 1992;31(13):3463-71.
1992: Julie D Forman-Kay; G Marius Clore; Angela M Gronenborn
Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR.
Biochemistry 1992;31(13):3442-52.
1992: G Marius Clore; Angela M Gronenborn
Localization of bound water in the solution structure of the immunoglobulin binding domain of streptococcal protein G. Evidence for solvent-induced helical distortion in solution.
Journal of molecular biology 1992;223(4):853-6.
1991: James G. Omichinski; G Marius Clore; Kazuyasu Sakaguchi; Ettore Appella; Angela M Gronenborn
Structural characterization of a 39-residue synthetic peptide containing the two zinc binding domains from the HIV-1 p7 nucleocapsid protein by CD and NMR spectroscopy.
FEBS letters 1991;292(1-2):25-30.
1991: Robert Powers; G Marius Clore; Adriaan Bax; Daniel S Garrett; Stephen J Stahl; Paul T Wingfield; Angela M Gronenborn
Secondary structure of the ribonuclease H domain of the human immunodeficiency virus reverse transcriptase in solution using three-dimensional double and triple resonance heteronuclear magnetic resonance spectroscopy.
Journal of molecular biology 1991;221(4):1081-90.
1991: G Marius Clore; Angela M Gronenborn
Comparison of the solution nuclear magnetic resonance and X-ray crystal structures of human recombinant interleukin-1 beta.
Journal of molecular biology 1991;221(1):47-53.
1991: Angela M Gronenborn; D R Filpula; N Z Essig; A Achari; M Whitlow; Paul T Wingfield; G Marius Clore
A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G.
Science (New York, N.Y.) 1991;253(5020):657-61.
1991: Julie D Forman-Kay; Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1991;220(2):209-16.
1991: G Marius Clore; Angela M Gronenborn
Structures of larger proteins in solution: three- and four-dimensional heteronuclear NMR spectroscopy.
Science (New York, N.Y.) 1991;252(5011):1390-9.
1991: G Marius Clore; Adriaan Bax; Angela M Gronenborn
Stereospecific assignment of beta-methylene protons in larger proteins using 3D 15N-separated Hartmann-Hahn and 13C-separated rotating frame Overhauser spectroscopy.
Journal of biomolecular NMR 1991;1(1):13-22.
1991: Kazuyasu Sakaguchi; Ettore Appella; James G. Omichinski; G Marius Clore; Angela M Gronenborn
Specific DNA binding to a major histocompatibility complex enhancer sequence by a synthetic 57-residue double zinc finger peptide from a human enhancer binding protein.
The Journal of biological chemistry 1991;266(11):7306-11.
1991: Julie D Forman-Kay; G Marius Clore; Paul T Wingfield; Angela M Gronenborn
High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry 1991;30(10):2685-98.
1991: G Marius Clore; Paul T Wingfield; Angela M Gronenborn
High-resolution three-dimensional structure of interleukin 1 beta in solution by three- and four-dimensional nuclear magnetic resonance spectroscopy.
Biochemistry 1991;30(9):2315-23.
1991: G Marius Clore; Angela M Gronenborn
Comparison of the solution nuclear magnetic resonance and crystal structures of interleukin-8. Possible implications for the mechanism of receptor binding.
Journal of molecular biology 1991;217(4):611-20.
1991: Angela M Gronenborn; G Marius Clore
Modeling the three-dimensional structure of the monocyte chemo-attractant and activating protein MCAF/MCP-1 on the basis of the solution structure of interleukin-8.
Protein engineering 1991;4(3):263-9.
1991: G Marius Clore; Lewis E Kay; Adriaan Bax; Angela M Gronenborn
Four-dimensional 13C/13C-edited nuclear Overhauser enhancement spectroscopy of a protein in solution: application to interleukin 1 beta.
Biochemistry 1991;30(1):12-8.
1990: James G. Omichinski; G Marius Clore; Ettore Appella; Kazuyasu Sakaguchi; Angela M Gronenborn
High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution.
Biochemistry 1990;29(40):9324-34.
1990: S Patricia Becerra; G Marius Clore; Angela M Gronenborn; A R Karlström; Stephen J Stahl; Samuel H Wilson; P T Wingfield
Purification and characterization of the RNase H domain of HIV-1 reverse transcriptase expressed in recombinant Escherichia coli.
FEBS letters 1990;270(1-2):76-80.
1990: G Marius Clore; Adriaan Bax; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Assignment of the side-chain 1H and 13C resonances of interleukin-1 beta using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy.
Biochemistry 1990;29(35):8172-84.
1990: G Marius Clore; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Low resolution structure of interleukin-1 beta in solution derived from 1H-15N heteronuclear three-dimensional nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1990;214(4):811-7.
1990: G Marius Clore; P C Driscoll; Paul T Wingfield; Angela M Gronenborn
Analysis of the backbone dynamics of interleukin-1 beta using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy.
Biochemistry 1990;29(32):7387-401.
1990: Lewis E Kay; G Marius Clore; Adriaan Bax; Angela M Gronenborn
Four-dimensional heteronuclear triple-resonance NMR spectroscopy of interleukin-1 beta in solution.
Science (New York, N.Y.) 1990;249(4967):411-4.
1990: G Marius Clore; Adriaan Bax; Paul T Wingfield; Angela M Gronenborn
Identification and localization of bound internal water in the solution structure of interleukin 1 beta by heteronuclear three-dimensional 1H rotating-frame Overhauser 15N-1H multiple quantum coherence NMR spectroscopy.
Biochemistry 1990;29(24):5671-6.
1990: P C Driscoll; Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the secondary structure and molecular topology of interleukin-1 beta by use of two- and three-dimensional heteronuclear 15N-1H NMR spectroscopy.
Biochemistry 1990;29(19):4668-82.
1990: P C Driscoll; G Marius Clore; D Marion; Paul T Wingfield; Angela M Gronenborn
Complete resonance assignment for the polypeptide backbone of interleukin 1 beta using three-dimensional heteronuclear NMR spectroscopy.
Biochemistry 1990;29(14):3542-56.
1990: Michael Nilges; G Marius Clore; Angela M Gronenborn
1H-NMR stereospecific assignments by conformational data-base searches.
Biopolymers 1990;29(4-5):813-22.
1990: G Marius Clore; Ettore Appella; M Yamada; K Matsushima; Angela M Gronenborn
Three-dimensional structure of interleukin 8 in solution.
Biochemistry 1990;29(7):1689-96.
1990: J E Forman-Kay; Angela M Gronenborn; Lewis E Kay; Paul T Wingfield; G Marius Clore
Studies on the solution conformation of human thioredoxin using heteronuclear 15N-1H nuclear magnetic resonance spectroscopy.
Biochemistry 1990;29(6):1566-72.
1990: Angela M Gronenborn; Michael Nilges; R J Peanasky; G Marius Clore
Sequential resonance assignment and secondary structure determination of the Ascaris trypsin inhibitor, a member of a novel class of proteinase inhibitors.
Biochemistry 1990;29(1):183-9.
1990: Ettore Appella; K Matsushima; J J Oppenheim; T Yoshimura; E J Leonard; G Marius Clore; Angela M Gronenborn
Determination of the primary and secondary structure of NAP-1/IL-8 and a monocyte chemoattractant protein, MCP-1/MCAF.
Progress in clinical and biological research 1990;349():405-17.
1989: G Marius Clore; Ettore Appella; M Yamada; K Matsushima; Angela M Gronenborn
Determination of the secondary structure of interleukin-8 by nuclear magnetic resonance spectroscopy.
The Journal of biological chemistry 1989;264(32):18907-11.
1989: J Kraulis; G Marius Clore; Michael Nilges; T A Jones; G Pettersson; J Knowles; Angela M Gronenborn
Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing.
Biochemistry 1989;28(18):7241-57.
1989: Julie D Forman-Kay; G Marius Clore; P C Driscoll; Paul T Wingfield; F M Richards; Angela M Gronenborn
A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin.
Biochemistry 1989;28(17):7088-97.
1989: D Marion; P C Driscoll; Lewis E Kay; Paul T Wingfield; Adriaan Bax; Angela M Gronenborn; G Marius Clore
Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1 beta.
Biochemistry 1989;28(15):6150-6.
1989: Angela M Gronenborn; G Marius Clore
Analysis of the relative contributions of the nuclear Overhauser interproton distance restraints and the empirical energy function in the calculation of oligonucleotide structures using restrained molecular dynamics.
Biochemistry 1989;28(14):5978-84.
1989: Angela M Gronenborn; Paul T Wingfield; G Marius Clore
Determination of the secondary structure of the DNA binding protein Ner from phage Mu using 1H homonuclear and 15N-1H heteronuclear NMR spectroscopy.
Biochemistry 1989;28(12):5081-9.
1989: P J Folkers; G Marius Clore; P C Driscoll; J Dodt; S Köhler; Angela M Gronenborn
Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.
Biochemistry 1989;28(6):2601-17.
1989: P C Driscoll; Angela M Gronenborn; L Beress; G Marius Clore
Determination of the three-dimensional solution structure of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata: a study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing.
Biochemistry 1989;28(5):2188-98.
1989: P C Driscoll; G Marius Clore; L Beress; Angela M Gronenborn
A proton nuclear magnetic resonance study of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata: sequential and stereospecific resonance assignment and secondary structure.
Biochemistry 1989;28(5):2178-87.
1989: P C Driscoll; Angela M Gronenborn; G Marius Clore
The influence of stereospecific assignments on the determination of three-dimensional structures of proteins by nuclear magnetic resonance spectroscopy. Application to the sea anemone protein BDS-I.
FEBS letters 1989;243(2):223-33.
1989: Angela M Gronenborn; Adriaan Bax; Paul T Wingfield; G Marius Clore
A powerful method of sequential proton resonance assignment in proteins using relayed 15N-1H multiple quantum coherence spectroscopy.
FEBS letters 1989;243(1):93-8.
1988: G Marius Clore; Adriaan Bax; Paul T Wingfield; Angela M Gronenborn
Long-range 15N-1H correlation as an aid to sequential proton resonance assignment of proteins. Application to the DNA-binding protein ner from phage Mu.
FEBS letters 1988;238(1):17-21.