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Michael Alifrangis

Research Profile

Disorders

Falciparum Malaria

Chemicals & Drugs

Geographic Areas

Tanzania

Physiology

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Publications

TOP 3
Thomas T Thomsen; Elsa V E Tomás; Ib C Bygbjerg; Derek Charlwood; Helle H Hansson; Laura B Madsen; Michael Alifrangis
Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique.
Magatte Ndiaye; Roger Tine; Annie Abiola; Michael Alifrangis; Yemou Dieng; Babacar Faye; Rachel Hallett; Aminata Lo; Daouda Ndiaye; Jean-Louis Ndiaye; Oumar Gaye
Assessment of the molecular marker of Plasmodium falciparum chloroquine resistance (Pfcrt) in Senegal after several years of chloroquine withdrawal.
Madhav Adhikari; Michael Alifrangis; Dwij Raj Bhatta; Mallika Imwong; Samir Ranjitkar; Mette Leth Schousboe; Megha Raj Banjara
Genetic diversity of plasmodium vivax merozoite surface protein-3alpha (Pvmsp-3alpha) gene in Jhapa District of Nepal.

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All Publications

2013: Thomas T Thomsen; Elsa V E Tomás; Ib C Bygbjerg; Derek Charlwood; Helle H Hansson; Laura B Madsen; Michael Alifrangis
Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique.
The American journal of tropical medicine and hygiene 2013;88(3):536-41.
2012: Magatte Ndiaye; Roger Tine; Annie Abiola; Michael Alifrangis; Yemou Dieng; Babacar Faye; Rachel Hallett; Aminata Lo; Daouda Ndiaye; Jean-Louis Ndiaye; Oumar Gaye
Assessment of the molecular marker of Plasmodium falciparum chloroquine resistance (Pfcrt) in Senegal after several years of chloroquine withdrawal.
The American journal of tropical medicine and hygiene 2012;87(4):640-5.
2012: Madhav Adhikari; Michael Alifrangis; Dwij Raj Bhatta; Mallika Imwong; Samir Ranjitkar; Mette Leth Schousboe; Megha Raj Banjara
Genetic diversity of plasmodium vivax merozoite surface protein-3alpha (Pvmsp-3alpha) gene in Jhapa District of Nepal.
The Southeast Asian journal of tropical medicine and public health 2012;43(2):280-6.
2012: George O Adjei; Michael Alifrangis; Lotte C Hoegberg; Jørgen A L Kurtzhals; Collins Oduro-Boatey; Onike P Rodrigues; Bamenla Q Goka
Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine.
Malaria journal 2012;11():420.
2012: Roger C K Tine; Michael Alifrangis; Ib C Bygbjerg; Babacar Faye; Helle Holm Hansson; Pascal Magnussen; Jean-Louis Ndiaye; Magatte Ndiaye; Cheikh T Ndour; K Sylla; Oumar Gaye
The association between malaria parasitaemia, erythrocyte polymorphisms, malnutrition and anaemia in children less than 10 years in Senegal: a case control study.
BMC research notes 2012;5():565.
2012: Daniel T Minja; Mayke Oesterholt; Caroline Pehrson; Ali Salanti; Christentze Schmiegelow; Thor Theander; Michael Alifrangis; Daniel Andersen; Stéphanie Boström; Philippe Deloron; Davis John; Martha M Lemnge; Adrian J F Luty; Pamela Magistrado; John P A Lusingu
Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.
Malaria journal 2012;11():211.
2012: Yahya A Derua; Kenneth M Hosea; Stephen M Magesa; Dan W Meyrowitsch; Erling M Pedersen; Michael Alifrangis; Paul Simonsen
Change in composition of the Anopheles gambiae complex and its possible implications for the transmission of malaria and lymphatic filariasis in north-eastern Tanzania.
Malaria journal 2012;11():188.
2012: Christian W Wang; Michael Alifrangis; Dominique C Bengtsson; Sanne S Berger; Thomas Lavstsen; John P A Lusingu; Pamela Magistrado; Andrea M Marquard; Thor G Theander; Louise Turner
Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.
Malaria journal 2012;11():129.
2011: Mette L Schousboe; Priyanie H Amerasinghe; Ib C Bygbjerg; Flemming Konradsen; Rosalynn Ord; Richard Pearce; Rupika S Rajakaruna; Cally Roper; Michael Alifrangis
Analysis of polymorphisms in the merozoite surface protein-3α gene and two microsatellite loci in Sri Lankan Plasmodium vivax: evidence of population substructure in Sri Lanka.
The American journal of tropical medicine and hygiene 2011;85(6):994-1001.
2011: Thomas T Thomsen; Lasse S Vestergaard; Ib C Bygbjerg; Deus S Ishengoma; Martha M Lemnge; John P A Lusingu; Bruno P Mmbando; Thor G Theander; Michael Alifrangis
Prevalence of single nucleotide polymorphisms in the Plasmodium falciparum multidrug resistance gene (Pfmdr-1) in Korogwe District in Tanzania before and after introduction of artemisinin-based combination therapy.
The American journal of tropical medicine and hygiene 2011;85(6):979-83.
2011: Jenny J Zhang; Michael Alifrangis; Priyanie H Amerasinghe; Rachel Daniels; Flemming Konradsen; Rupika Rajakaruna; Tharanga N Senaratne; Clarissa Valim; Dyann F Wirth; Nadira D Karunaweera
Distribution pattern of Plasmodium falciparum chloroquine transporter (pfcrt) gene haplotypes in Sri Lanka 1996-2006.
The American journal of tropical medicine and hygiene 2011;85(5):811-4.
2011: Insaf F Khalil; Ulla Abildrup; Lene H Alifrangis; Deogratius Maiga; Michael Alifrangis; Lotte Hoegberg; Lasse S Vestergaard; Ola Per-Eric Persson; Nyagonde Nyagonde; Martha M Lemnge; Thor G Theander; Ib C Bygbjerg
Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection.
Journal of pharmaceutical and biomedical analysis 2011;54(1):168-72.
2011: Insaf F Khalil; Michael Alifrangis; Ib C Bygbjerg; Lotte C Hoegberg; Camilla Recke; Anita Ronn; Claus Koch
Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations.
Malaria journal 2011;10():249.
2011: Dan W Meyrowitsch; Edwin Michael; Erling M Pedersen; Rwehumbiza T Rwegoshora; Thomas H Scheike; Michael Alifrangis; Yahya A Derua; Stephen M Magesa; Mwelecele N Malecela; Paul Simonsen
Is the current decline in malaria burden in sub-Saharan Africa due to a decrease in vector population?
Malaria journal 2011;10():188.
2011: Deus S Ishengoma; Michael Alifrangis; Ib C Bygbjerg; Filbert Francis; John P A Lusingu; Pamela Magistrado; Bruno P Mmbando; Thor G Theander; Martha M Lemnge
Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania.
Malaria journal 2011;10():176.
2011: Samir Ranjitkar; Mette L Schousboe; Thomas Thyge Thomsen; Madhav Adhikari; Christian M O Kapel; Ib C Bygbjerg; Michael Alifrangis
Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal.
Malaria journal 2011;10():75.
2011: Deus S Ishengoma; Sudi Lwitiho; Rashid A Madebe; Nyagonde Nyagonde; Ola Persson; Lasse S Vestergaard; Ib C Bygbjerg; Martha M Lemnge; Michael Alifrangis
Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence.
Malaria journal 2011;10():6.
2010: Sharmini Gunawardena; Nadira D Karunaweera; Marcelo U Ferreira; Myatt Phone-Kyaw; Richard J Pollack; Michael Alifrangis; Rupika S Rajakaruna; Flemming Konradsen; Priyanie H Amerasinghe; Mette L Schousboe; Gawrie N L Galappaththy; Rabindra R Abeyasinghe; Daniel L Hartl; Dyann F Wirth
Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia.
The American journal of tropical medicine and hygiene 2010;82(2):235-42.
2010: Rupika S Rajakaruna; Michael Alifrangis; Priyanie H Amerasinghe; Flemming Konradsen
Pre-elimination stage of malaria in Sri Lanka: assessing the level of hidden parasites in the population.
Malaria journal 2010;9():25.
2010: Dan W Meyrowitsch; Paul Simonsen; Peter Garred; Michael B Dalgaard; Stephen M Magesa; Michael Alifrangis
Association between mannose-binding lectin polymorphisms and Wuchereria bancrofti infection in two communities in North-Eastern Tanzania.
The American journal of tropical medicine and hygiene 2010;82(1):115-20.
2009: Michael Alifrangis; John P A Lusingu; Bruno P Mmbando; Michael B Dalgaard; Lasse S Vestergaard; Deus Ishengoma; Insaf F Khalil; Thor G Theander; Martha M Lemnge; Ib C Bygbjerg
Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation of the 581G mutation in the P. falciparum dihydropteroate synthase gene.
The American journal of tropical medicine and hygiene 2009;80(4):523-7.
2009: Seif Shekalaghe; Michael Alifrangis; Charles Mwanziva; Anders Enevold; Steve Mwakalinga; Humphrey Mkali; Reginald Kavishe; Alphaxard Manjurano; Robert W Sauerwein; Chris Drakeley; Teun Bousema
Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparum specific immune responses in a low endemic area in northern Tanzania.
BMC infectious diseases 2009;9():69.
2009: Mayke J A M Oesterholt; Michael Alifrangis; Colin J Sutherland; Sabah A Omar; Patrick Sawa; Christina Howitt; Louis C Gouagna; Robert W Sauerwein; Teun Bousema
Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya.
PloS one 2009;4(2):e4364.
2008: George O Adjei; Kim Kristensen; Bamenla Q Goka; Lotte C G Hoegberg; Michael Alifrangis; Onike Rodrigues; Jørgen A L Kurtzhals
Effect of concomitant artesunate administration and cytochrome P4502C8 polymorphisms on the pharmacokinetics of amodiaquine in Ghanaian children with uncomplicated malaria.
Antimicrobial agents and chemotherapy 2008;52(12):4400-6.
2008: Ishraga E A-Elbasit; Insaf F Khalil; Mustafa I Elbashir; E M Masuadi; Ib C Bygbjerg; Michael Alifrangis; Hayder A Giha
High frequency of Plasmodium falciparum CICNI/SGEAA and CVIET haplotypes without association with resistance to sulfadoxine/pyrimethamine and chloroquine combination in the Daraweesh area, in Sudan.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2008;27(8):725-32.
2008: Rajeev K Mehlotra; Gabriel Mattera; Moses J Bockarie; Jason D Maguire; J Kevin Baird; Yagya D Sharma; Michael Alifrangis; Grant Dorsey; Philip J Rosenthal; David J Fryauff; James W Kazura; Mark Stoneking; Peter Zimmerman
Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2008;52(6):2212-22.
2008: Lasse S Vestergaard; John P A Lusingu; Morten A Nielsen; Bruno P Mmbando; Daniel Dodoo; Bartholomew Akanmori; Michael Alifrangis; Ib C Bygbjerg; Martha M Lemnge; Trine Staalsoe; Lars Hviid; Thor G Theander
Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania.
Infection and immunity 2008;76(6):2706-14.
2008: Anders Enevold; John P A Lusingu; Bruno P Mmbando; Michael Alifrangis; Martha M Lemnge; Ib C Bygbjerg; Thor G Theander; Lasse S Vestergaard
Reduced risk of uncomplicated malaria episodes in children with alpha+-thalassemia in northeastern Tanzania.
The American journal of tropical medicine and hygiene 2008;78(5):714-20.
2008: George O Adjei; Jørgen A L Kurtzhals; Onike Rodrigues; Michael Alifrangis; Lotte C G Hoegberg; Emmanuel D Kitcher; Ebenezer V Badoe; Roberta Lamptey; Bamenla Q Goka
Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up.
Malaria journal 2008;7():127.
2008: Sonia Enosse; Pascal Magnussen; Fatima Abacassamo; Xavier Gómez-Olivé; Anita M Rønn; Ricardo Thompson; Michael Alifrangis
Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique.
Malaria journal 2008;7():115.
2008: Nabil Sabri Enattah; Tine G K Jensen; Mette Nielsen; Rikke Lewinski; Mikko Kuokkanen; Heli Rasinpera; Hatem El-Shanti; Jeong Kee Seo; Michael Alifrangis; Insaf F Khalil; Abdrazak Natah; Ahmed Ali; Sirajedin Natah; David Comas; S Qasim Mehdi; Leif Groop; Else Marie Vestergaard; Faiqa Imtiaz; Mohamed S Rashed; Brian Meyer; Jesper T Troelsen; Leena Peltonen
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.
American journal of human genetics 2008;82(1):57-72.
2007: Nabil Sabri Enattah; Aimee Trudeau; Ville Pimenoff; Luigi Maiuri; Salvatore Auricchio; Luigi Greco; Mauro Rossi; Michael Lentze; J K Seo; Soheila Rahgozar; Insaf F Khalil; Michael Alifrangis; Sirajedin Natah; Leif Groop; Nael Shaat; Andrew Kozlov; Galina Verschubskaya; David Comas; Kazima B Bulayeva; S Qasim Mehdi; Joseph D Terwilliger; Timo Sahi; Erkki Savilahti; Markus Perola; Antti Sajantila; Irma Järvelä; Leena Peltonen
Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans.
American journal of human genetics 2007;81(3):615-25.
2007: Morten A Nielsen; Mafalda Resende; Michael Alifrangis; Louise Turner; Lars Hviid; Thor G Theander; Ali Salanti
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin.
Experimental parasitology 2007;117(1):1-8.
2007: Anders Enevold; Michael Alifrangis; Juan J Sanchez; Ilona Carneiro; Cally Roper; Claus Børsting; John P A Lusingu; Lasse S Vestergaard; Martha M Lemnge; Niels Morling; Eleanor Riley; Chris Drakeley
Associations between alpha+-thalassemia and Plasmodium falciparum malarial infection in northeastern Tanzania.
The Journal of infectious diseases 2007;196(3):451-9.
2007: Anders Enevold; Watoky M M M Nkya; Michael Theisen; Lasse S Vestergaard; Anja T R Jensen; Trine Staalsoe; Thor G Theander; Ib C Bygbjerg; Michael Alifrangis
Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum.
Malaria journal 2007;6():153.
2007: Seif Shekalaghe; Chris Drakeley; Roly Gosling; Arnold Ndaro; Monique van Meegeren; Anders Enevold; Michael Alifrangis; Frank Mosha; Robert W Sauerwein; Teun Bousema
Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.
PloS one 2007;2(10):e1023.
2007: Ishraga E A-Elbasit; Michael Alifrangis; Insaf F Khalil; Ib C Bygbjerg; Emad M Masuadi; Mustafa I Elbashir; Hayder A Giha
The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics.
Malaria journal 2007;6():108.
2007: Mette L Schousboe; Rupika S Rajakaruna; Ali Salanti; Hapuarachchige C Hapuarachchi; Gawrie N L Galappaththy; Ib C Bygbjerg; Priyanie H Amerasinghe; Flemming Konradsen; Michael Alifrangis
Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka.
Malaria journal 2007;6():28.
2007: A M Ibrahium; Musa M Kheir; Maha E Osman; Insaf F Khalil; Michael Alifrangis; Khalid A Elmardi; Elfatih M Mohamed Malik; Ishag Adam
Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.
Annals of tropical medicine and parasitology 2007;101(1):15-21.
2006: Martha M Lemnge; Michael Alifrangis; Mwanaidi Y Kafuye; Method D Segeja; Samwel Gesase; Daniel T Minja; Julius J Massaga; Anita M Rønn; Ib C Bygbjerg
High reinfection rate and treatment failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania.
The American journal of tropical medicine and hygiene 2006;75(2):188-93.
2006: Michael Alifrangis; Michael B Dalgaard; John P A Lusingu; Lasse S Vestergaard; Trine Staalsoe; Anja T R Jensen; Anders Enevold; Anita M Rønn; Insaf F Khalil; david charles warhurst; Martha M Lemnge; Thor G Theander; Ib C Bygbjerg
Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania.
The Journal of infectious diseases 2006;193(12):1738-41.
2006: R S Rajakaruna; Manjula Weerasinghe; Michael Alifrangis; Priyanie H Amerasinghe; Flemming Konradsen
The role of private drug vendors as malaria treatment providers in selected malaria endemic areas of Sri Lanka.
Journal of vector borne diseases 2006;43(2):58-65.
2006: Ishraga E A-Elbasit; Mustafa I Elbashir; Insaf F Khalil; Michael Alifrangis; Hayder A Giha
The efficacy of sulfadoxine-pyrimethamine alone and in combination with chloroquine for malaria treatment in rural Eastern Sudan: the interrelation between resistance, age and gametocytogenesis.
Tropical medicine & international health : TM & IH 2006;11(5):604-12.
2006: Ishag Adam; Mamoun Magzoub; Maha E Osman; Insaf F Khalil; Michael Alifrangis; Khalid A Elmardi
A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan.
Annals of clinical microbiology and antimicrobials 2006;5():18.
2006: Manisha A Kulkarni; Mark Rowland; Michael Alifrangis; Frank Mosha; Johnson Matowo; Robert Malima; Justin Peter; Eliningaya Kweka; Issa Lyimo; Stephen M Magesa; Ali Salanti; Manfred E Rau; Chris Drakeley
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
Malaria journal 2006;5():56.
2005: Sabine Dittrich; Michael Alifrangis; Jörg M Stohrer; Vonthalom Thongpaseuth; Viengxay Vanisaveth; Rattanaxay Phetsouvanh; Samlane Phompida; Insaf F Khalil; Tomas Jelinek
Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT.
Tropical medicine & international health : TM & IH 2005;10(12):1267-70.
2005: Priyanie H Amerasinghe; Michael Alifrangis; Wim van der Hoek; Robert A Wirtz; Felix P Amerasinghe; Flemming Konradsen
Optimizing malarial epidemiological studies in areas of low transmission.
The Southeast Asian journal of tropical medicine and public health 2005;36(5):1079-84.
2005: Insaf F Khalil; Anita M Rønn; Michael Alifrangis; Haythem A Gabar; Tomas Jelinek; Gwiria M H Satti; Ib C Bygbjerg
Response of Plasmodium falciparum to cotrimoxazole therapy: relationship with plasma drug concentrations and dihydrofolate reductase and dihydropteroate synthase genotypes.
The American journal of tropical medicine and hygiene 2005;73(1):174-7.
2005: Insaf F Khalil; Michael Alifrangis; Donath S Tarimo; T Staalsø; Gwiria M H Satti; Thor G Theander; Anita M Rønn; Ib C Bygbjerg
The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities.
Annals of tropical medicine and parasitology 2005;99(5):441-8.
2005: Michael Alifrangis; Sonia Enosse; Richard Pearce; Chris Drakeley; Cally Roper; Insaf F Khalil; Watoky M M M Nkya; Anita M Rønn; Thor G Theander; Ib C Bygbjerg
A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology.
The American journal of tropical medicine and hygiene 2005;72(2):155-62.
2005: Anders Enevold; Lasse S Vestergaard; John P A Lusingu; Chris Drakeley; Martha M Lemnge; Thor G Theander; Ib C Bygbjerg; Michael Alifrangis
Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method.
Malaria journal 2005;4():61.
2005: John P A Lusingu; Lasse S Vestergaard; Michael Alifrangis; Bruno P Mmbando; Michael Theisen; Andrew Y Kitua; Martha M Lemnge; Thor G Theander
Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission.
Malaria journal 2005;4():48.
2004: Ole Wichmann; Nikolai Muehlberger; Tomas Jelinek; Michael Alifrangis; Gabriele Peyerl-Hoffmann; Marion Muhlen; Martin P Grobusch; Joaquim Gascon; Alberto Matteelli; Hermann Laferl; Zeno Bisoffi; Stephan Ehrhardt; Juan Cuadros; Christoph Hatz; Ida Gjorup; Paul McWhinney; Jiri Beran; Saraiva da Cunha; Marco Schulze; Herwig Kollaritsch; Peter Kern; Graham Fry; Joachim Richter
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe.
The Journal of infectious diseases 2004;190(9):1541-6.
2004: Michael Alifrangis; Inge T Christensen; Flemming Steen Jørgensen; Anita M Rønn; Jimmy E Weng; Ming Chen; Ib C Bygbjerg; Worachart Sirawaraporn; Yaseelan Palarasah; Claus Koch
Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum.
Malaria journal 2004;3():16.
2003: Michael Alifrangis; Sonia Enosse; Insaf F Khalil; Donath S Tarimo; Martha M Lemnge; Ricardo Thompson; Ib C Bygbjerg; Anita M Rønn
Prediction of Plasmodium falciparum resistance to sulfadoxine/pyrimethamine in vivo by mutations in the dihydrofolate reductase and dihydropteroate synthetase genes: a comparative study between sites of differing endemicity.
The American journal of tropical medicine and hygiene 2003;69(6):601-6.
2003: Michael Alifrangis; Martha M Lemnge; Anita M Rønn; Method D Segeja; Stephen M Magesa; Insaf F Khalil; Ib C Bygbjerg
Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets.
The American journal of tropical medicine and hygiene 2003;69(3):238-43.
2003: Ole Wichmann; Tomas Jelinek; Gabriele Peyerl-Hoffmann; Nikolai Mühlberger; Martin P Grobusch; Joaquim Gascon; Alberto Matteelli; Christoph Hatz; Hermann Laferl; Marco Schulze; Gerd D Burchard; Saraiva da Cunha; Jiri Beran; Paul McWhinney; Herwig Kollaritsch; Peter Kern; Juan Cuadros; Michael Alifrangis; Ida Gjørup
Molecular surveillance of the antifolate-resistant mutation I164L in imported African isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop.
Malaria journal 2003;2():17.
2003: Insaf F Khalil; Anita M Rønn; Michael Alifrangis; Haythem A Gabar; Gwiria M H Satti; Ib C Bygbjerg
Dihydrofolate reductase and dihydropteroate synthase genotypes associated with in vitro resistance of Plasmodium falciparum to pyrimethamine, trimethoprim, sulfadoxine, and sulfamethoxazole.
The American journal of tropical medicine and hygiene 2003;68(5):586-9.
2003: Babett Schwöbel; Michael Alifrangis; Ali Salanti; Tomas Jelinek
Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker.
Malaria journal 2003;2():5.
2003: Kim P David; Michael Alifrangis; Ali Salanti; Lasse S Vestergaard; Anita M Rønn; I B Bygbjerg
Atovaquone/proguanil resistance in Africa: a case report.
Scandinavian journal of infectious diseases 2003;35(11-12):897-8.
2002: Stephen M Magesa; KY Mdira; Hamza A Babiker; Michael Alifrangis; Anna Färnert; Paul Simonsen; Ib C Bygbjerg; David Walliker; PH Jakobsen
Diversity of Plasmodium falciparum clones infecting children living in a holoendemic area in north-eastern Tanzania.
Acta tropica 2002;84(2):83-92.
2002: Tomas Jelinek; Gabriele Peyerl-Hoffmann; Nikolai Mühlberger; Ole Wichmann; Michael Wilhelm; Nadja Schmider; Martin P Grobusch; Frank von Sonnenburg; Joaquim Gascon; Hermann Laferl; Christoph Hatz; Michael Alifrangis; Gerd D Burchard; Paul McWhinney; Marco Schulze; Herwig Kollaritsch; Saraiva da Cunha; Jiri Beran; Peter Kern; Ida Gjørup; Juan Cuadros
Molecular surveillance of drug resistance through imported isolates of Plasmodium falciparum in Europe.
Malaria journal 2002;1():11.
2002: Insaf F Khalil; Michael Alifrangis; Anita M Rønn; Haythem A Gabar; Tomas Jelinek; Gwiria M H Satti; Ib C Bygbjerg
Pyrimethamine/sulfadoxine combination in the treatment of uncomplicated falciparum malaria: relation between dihydropteroate synthase/dihydrofolate reductase genotypes, sulfadoxine plasma levels, and treatment outcome.
The American journal of tropical medicine and hygiene 2002;67(3):225-9.
2002: Morten A Nielsen; Trine Staalsoe; Jørgen A L Kurtzhals; Bamenla Q Goka; Daniel Dodoo; Michael Alifrangis; Thor G Theander; Bartholomew Akanmori; Lars Hviid
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3444-50.
1999: Michael Alifrangis; Martha M Lemnge; R Moon; Michael Theisen; Ib C Bygbjerg; RG Ridley; PH Jakobsen
IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children.
Parasitology 1999;119 ( Pt 4)():337-42.