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Anthony Coates

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Living Beings

Chemicals & Drugs

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Genes & Molecular Sequences

Physiology

Gene Expression Regulation, Bacterial

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Publications

TOP 3
Yanmin Hu; Anthony R M Coates
Enhancement by novel anti-methicillin-resistant Staphylococcus aureus compound HT61 of the activity of neomycin, gentamicin, mupirocin and chlorhexidine: in vitro and in vivo studies.
Yanira Riffo-Vasquez; Anthony R M Coates; Clive P Page; Domenico Spina
Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation.
Anthony R M Coates; Gerry Halls
Antibiotics in phase II and III clinical trials.

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All Publications

2013: Yanmin Hu; Anthony R M Coates
Enhancement by novel anti-methicillin-resistant Staphylococcus aureus compound HT61 of the activity of neomycin, gentamicin, mupirocin and chlorhexidine: in vitro and in vivo studies.
The Journal of antimicrobial chemotherapy 2013;68(2):374-84.
2012: Yanira Riffo-Vasquez; Anthony R M Coates; Clive P Page; Domenico Spina
Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation.
American journal of respiratory cell and molecular biology 2012;47(2):245-52.
2012: Anthony R M Coates; Gerry Halls
Antibiotics in phase II and III clinical trials.
Handbook of experimental pharmacology 2012;(211):167-83.
2011: Elizabeth A C Haidar; Terence D Lee; Jonathan D Barton; Anthony R M Coates; Peter G Mantle
HPLC/MS/MS methodology for sensitive quantitation of monic acid A, the metabolic product of the antibiotic mupirocin.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011;16(5):422-5.
2011: Anthony R M Coates; Gerry Halls; Yanmin Hu
Novel classes of antibiotics or more of the same?
British journal of pharmacology 2011;163(1):184-94.
2011: Yanmin Hu; Anthony R M Coates
Mycobacterium tuberculosis acg gene is required for growth and virulence in vivo.
PloS one 2011;6(6):e20958.
2010: Ana Cehovin; Anthony R M Coates; Yanmin Hu; Yanira Riffo-Vasquez; Peter Tormay; Catherine Botanch; Frederic Altare; Brian Henderson
Comparison of the moonlighting actions of the two highly homologous chaperonin 60 proteins of Mycobacterium tuberculosis.
Infection and immunity 2010;78(7):3196-206.
2010: Brian Henderson; Peter Lund; Anthony R M Coates
Multiple moonlighting functions of mycobacterial molecular chaperones.
Tuberculosis (Edinburgh, Scotland) 2010;90(2):119-24.
2010: Brian Henderson; Stuart K Calderwood; Anthony R M Coates; Irun Cohen; Willem van Eden; Thomas Lehner; A Graham Pockley
Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants.
Cell stress & chaperones 2010;15(2):123-41.
2009: Yanmin Hu; Anthony R M Coates
Acute and persistent Mycobacterium tuberculosis infections depend on the thiol peroxidase TpX.
PloS one 2009;4(4):e5150.
2008: Jessica M T Barford; Yanmin Hu; Ken Anson; Anthony R M Coates
A biphasic response from bladder epithelial cells induced by catheter material and bacteria: an in vitro study of the pathophysiology of catheter related urinary tract infection.
The Journal of urology 2008;180(4):1522-6.
2008: Vivienne R Winrow; Jon Mesher; Sajeda Meghji; Christopher J Morris; Maria Maguire; Simon Fox; Anthony R M Coates; Peter Tormay; David R Blake; Brian Henderson
The two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts.
Cellular microbiology 2008;10(10):2091-104.
2008: Jessica M T Barford; Ken M Anson; Yanmin Hu; Anthony R M Coates
A model of catheter-associated urinary tract infection initiated by bacterial contamination of the catheter tip.
BJU international 2008;102(1):67-74.
2008: Yanmin Hu; Brian Henderson; Peter Lund; Peter Tormay; M Tabish Ahmed; Sudagar S Gurcha; Gurdyal S Besra; Anthony R M Coates
A Mycobacterium tuberculosis mutant lacking the groEL homologue cpn60.1 is viable but fails to induce an inflammatory response in animal models of infection.
Infection and immunity 2008;76(4):1535-46.
2008: Anthony R M Coates; Yanmin Hu
Targeting non-multiplying organisms as a way to develop novel antimicrobials.
Trends in pharmacological sciences 2008;29(3):143-50.
2008: Anthony R M Coates; Ana Cehovin; Yanmin Hu
Chaperonin 60 and macrophage activation.
Novartis Foundation symposium 2008;291():160-9; discussion 169-72, 221-4.
2008: Y Hu; Anthony R M Coates; Denis A Mitchison
Comparison of the sterilising activities of the nitroimidazopyran PA-824 and moxifloxacin against persisting Mycobacterium tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2008;12(1):69-73.
2007: Andrew Steptoe; Alireza Shamaei-Tousi; Asa Gylfe; L Bailey; S Bergström; Anthony R M Coates; Brian Henderson
Protective effect of human heat shock protein 60 suggested by its association with decreased seropositivity to pathogens.
Clinical and vaccine immunology : CVI 2007;14(2):204-7.
2007: Jo C Lewthwaite; Claire E Clarkin; Anthony R M Coates; Stephen Poole; Rachel Lawrence; Caroline P D Wheeler-Jones; Andrew A Pitsillides; Mahavir Singh; Brian Henderson
Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases.
International immunopharmacology 2007;7(2):230-40.
2007: Alireza Shamaei-Tousi; Andrew Steptoe; Katie O'Donnell; Jutta Palmen; Jeffrey W Stephens; Steven J Hurel; Michael Marmot; Karen Homer; Francesco D'Aiuto; Anthony R M Coates; Steve E Humphries; Brian Henderson
Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors.
Cell stress & chaperones 2007;12(4):384-92.
2007: Alireza Shamaei-Tousi; Francesco D'Aiuto; Luigi Nibali; Andrew Steptoe; Anthony R M Coates; Mohamed Hussein Parkar; Nikolaos Donos; Brian Henderson
Differential regulation of circulating levels of molecular chaperones in patients undergoing treatment for periodontal disease.
PloS one 2007;2(11):e1198.
2006: Brian Henderson; Elaine Allan; Anthony R M Coates
Stress wars: the direct role of host and bacterial molecular chaperones in bacterial infection.
Infection and immunity 2006;74(7):3693-706.
2006: Alireza Shamaei-Tousi; Jeffrey W Stephens; Ren Bin; Jacqueline A Cooper; Andrew Steptoe; Anthony R M Coates; Brian Henderson; Steve E Humphries
Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus.
European heart journal 2006;27(13):1565-70.
2006: Y Hu; Anthony R M Coates; Denis A Mitchison
Sterilising action of pyrazinamide in models of dormant and rifampicin-tolerant Mycobacterium tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2006;10(3):317-22.
2006: Yanmin Hu; Farahnaz Movahedzadeh; neil stoker; Anthony R M Coates
Deletion of the Mycobacterium tuberculosis alpha-crystallin-like hspX gene causes increased bacterial growth in vivo.
Infection and immunity 2006;74(2):861-8.
2006: Anthony R M Coates; Yanmin Hu
New strategies for antibacterial drug design: targeting non-multiplying latent bacteria.
Drugs in R&D 2006;7(3):133-51.
2005: julian halcox; John Deanfield; Alireza Shamaei-Tousi; Brian Henderson; Andrew Steptoe; Anthony R M Coates; Atul Singhal; Alan Lucas
Circulating human heat shock protein 60 in the blood of healthy teenagers: a novel determinant of endothelial dysfunction and early vascular injury?
Arteriosclerosis, thrombosis, and vascular biology 2005;25(11):e141-2.
2005: Rohini Qamra; Shekhar C Mande; Anthony R M Coates; Brian Henderson
The unusual chaperonins of Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) 2005;85(5-6):385-94.
2005: Maria Maguire; Stephen Poole; Anthony R M Coates; Peter Tormay; Caroline P D Wheeler-Jones; Brian Henderson
Comparative cell signalling activity of ultrapure recombinant chaperonin 60 proteins from prokaryotes and eukaryotes.
Immunology 2005;115(2):231-8.
2005: Peter Tormay; Anthony R M Coates; Brian Henderson
The intercellular signaling activity of the Mycobacterium tuberculosis chaperonin 60.1 protein resides in the equatorial domain.
The Journal of biological chemistry 2005;280(14):14272-7.
2005: Yanmin Hu; Anthony R M Coates
Transposon mutagenesis identifies genes which control antimicrobial drug tolerance in stationary-phase Escherichia coli.
FEMS microbiology letters 2005;243(1):117-24.
2004: Gianluca Fossati; Pietro Cremonesi; Gaetano Izzo; Emanuele Rizzi; Giovanni Sandrone; Stephen Harding; Neil Errington; Christopher Walters; Brian Henderson; Michael M Roberts; Anthony R M Coates; Paolo Mascagni
The Mycobacterium tuberculosis chaperonin 10 monomer exhibits structural plasticity.
Biopolymers 2004;75(2):148-62.
2004: Yanmin Hu; Sharon Kendall; neil stoker; Anthony R M Coates
The Mycobacterium tuberculosis sigJ gene controls sensitivity of the bacterium to hydrogen peroxide.
FEMS microbiology letters 2004;237(2):415-23.
2004: Denis A Mitchison; Anthony R M Coates
Predictive in vitro models of the sterilizing activity of anti-tuberculosis drugs.
Current pharmaceutical design 2004;10(26):3285-95.
2003: Gianluca Fossati; Gaetano Izzo; Emanuele Rizzi; Emanuela Gancia; Daniela Modena; Maria Luisa Moras; Neri Niccolai; Elena Giannozzi; ottavia spiga; Letizia Bono; Piero Marone; Eugenio Leone; Francesca Mangili; Stephen Harding; Neil Errington; Christopher Walters; Brian Henderson; Michael M Roberts; Anthony R M Coates; Bruno Casetta; Paolo Mascagni
Mycobacterium tuberculosis chaperonin 10 is secreted in the macrophage phagosome: is secretion due to dissociation and adoption of a partially helical structure at the membrane?
Journal of bacteriology 2003;185(14):4256-67.
2003: Michael M Roberts; Alun R Coker; Gianluca Fossati; Paolo Mascagni; Anthony R M Coates; Steve P Wood
Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops.
Journal of bacteriology 2003;185(14):4172-85.
2003: Maria Maguire; Anthony R M Coates; Brian Henderson
Cloning, expression and purification of three Chaperonin 60 homologues.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;786(1-2):117-25.
2003: Yanmin Hu; Anthony R M Coates; Denis A Mitchison
Sterilizing activities of fluoroquinolones against rifampin-tolerant populations of Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2003;47(2):653-7.
2002: Maria Maguire; Anthony R M Coates; Brian Henderson
Chaperonin 60 unfolds its secrets of cellular communication.
Cell stress & chaperones 2002;7(4):317-29.
2002: Jo C Lewthwaite; Roger George; Peter Lund; Stephen Poole; Peter Tormay; Lindsay Sharp; Anthony R M Coates; Brian Henderson
Rhizobium leguminosarum chaperonin 60.3, but not chaperonin 60.1, induces cytokine production by human monocytes: activity is dependent on interaction with cell surface CD14.
Cell stress & chaperones 2002;7(2):130-6.
2001: Jo C Lewthwaite; Anthony R M Coates; Peter Tormay; Mahavir Singh; Paolo Mascagni; Stephen Poole; M Roberts; Lindsay Sharp; Brian Henderson
Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain.
Infection and immunity 2001;69(12):7349-55.
2001: Y Hu; Anthony R M Coates
Increased levels of sigJ mRNA in late stationary phase cultures of Mycobacterium tuberculosis detected by DNA array hybridisation.
FEMS microbiology letters 2001;202(1):59-65.
2000: Yanmin Hu; Joseph A Mangan; Jasvir Dhillon; KM Sole; Denis A Mitchison; Philip Butcher; Anthony R M Coates
Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide.
Journal of bacteriology 2000;182(22):6358-65.
2000: Julia C Ranford; Anthony R M Coates; Brian Henderson
Chaperonins are cell-signalling proteins: the unfolding biology of molecular chaperones.
Expert reviews in molecular medicine 2000;2(8):1-17.
1999: Ida Rosenkrands; Karin Weldingh; Pernille Ravn; Lise Brandt; P Højrup; PB Rasmussen; Anthony R M Coates; M Singh; Paolo Mascagni; Peter Andersen
Differential T-cell recognition of native and recombinant Mycobacterium tuberculosis GroES.
Infection and immunity 1999;67(11):5552-8.
1999: Yanmin Hu; Philip Butcher; Joseph A Mangan; M A Rajandream; Anthony R M Coates
Regulation of hmp gene transcription in Mycobacterium tuberculosis: effects of oxygen limitation and nitrosative and oxidative stress.
Journal of bacteriology 1999;181(11):3486-93.
1999: Michael M Roberts; Alun R Coker; Gianluca Fossati; Paolo Mascagni; Anthony R M Coates; Steve P Wood
Crystallization, x-ray diffraction and preliminary structure analysis of Mycobacterium tuberculosis chaperonin 10.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 4):910-4.
1999: Yanmin Hu; Anthony R M Coates
Transcription of the stationary-phase-associated hspX gene of Mycobacterium tuberculosis is inversely related to synthesis of the 16-kilodalton protein.
Journal of bacteriology 1999;181(5):1380-7.
1999: Anthony R M Coates; B Henderson; Paolo Mascagni
The unfolding story of the chaperonins.
Biotechnology & genetic engineering reviews 1999;16():393-405.
1999: Yanmin Hu; Anthony R M Coates
Transcription of two sigma 70 homologue genes, sigA and sigB, in stationary-phase Mycobacterium tuberculosis.
Journal of bacteriology 1999;181(2):469-76.
1998: Jasvir Dhillon; B W Allen; Y M Hu; Anthony R M Coates; Denis A Mitchison
Metronidazole has no antibacterial effect in Cornell model murine tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1998;2(9):736-42.
1998: Anthony R M Coates; B Henderson
Chaperonins in health and disease.
Annals of the New York Academy of Sciences 1998;851():48-53.
1998: Y M Hu; Philip Butcher; KM Sole; Denis A Mitchison; Anthony R M Coates
Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock.
FEMS microbiology letters 1998;158(1):139-45.
1997: Sajeda Meghji; Peter White; Sean Nair; K Reddi; K Heron; Brian Henderson; Andrea Zaliani; Gianluca Fossati; Paolo Mascagni; J F Hunt; Michael M Roberts; Anthony R M Coates
Mycobacterium tuberculosis chaperonin 10 stimulates bone resorption: a potential contributory factor in Pott's disease.
The Journal of experimental medicine 1997;186(8):1241-6.
1997: HL Ball; A W Chan; W A Gibbons; Anthony R M Coates; Paolo Mascagni
The structural and aggregation properties of the synthetic C-terminal half (104-mer) polypeptide from HIV p24gag resemble those of full-length protein.
Journal of peptide science : an official publication of the European Peptide Society 1997;3(3):168-80.
1996: H al-Ghusein; H Ball; G L Igloi; A Gbewonyo; Anthony R M Coates; Paolo Mascagni; Michael M Roberts
Chemically synthesised human immunodeficiency virus P7 nucleocapsid protein can self-assemble into particles and binds to a specific site on the tRNA(Lys,3) primer.
Biochemical and biophysical research communications 1996;224(1):191-8.
1996: Brian Henderson; Sean Nair; Anthony R M Coates
Molecular chaperones and disease.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1996;45(4):155-8.
1995: Gianluca Fossati; P Lucietto; P Giuliani; Anthony R M Coates; S Harding; H Cölfen; G Legname; E Chan; Andrea Zaliani; Paolo Mascagni
Mycobacterium tuberculosis chaperonin 10 forms stable tetrameric and heptameric structures. Implications for its diverse biological activities.
The Journal of biological chemistry 1995;270(44):26159-67.
1995: E Chan; Gianluca Fossati; P Giuliani; P Lucietto; Andrea Zaliani; Anthony R M Coates; Paolo Mascagni
Sequence and structural homologies between M. tuberculosis chaperonin 10 and the MHC class I/II peptide binding cleft.
Biochemical and biophysical research communications 1995;211(1):14-20.
1995: JC Booth; Sirimali Fernando; D Carrington; Mark R W Evans; P Hay; Anthony R M Coates
The detection of HIV-1 proviral DNA by PCR in clotted blood specimens.
Journal of virological methods 1995;52(1-2):87-94.
1994: D Atkins; H al-Ghusein; C Prehaud; Anthony R M Coates
Overproduction and purification of Mycobacterium tuberculosis chaperonin 10.
Gene 1994;150(1):145-8.
1994: Yury S Boriskin; JC Booth; M M Roberts; D Carrington; Anthony R M Coates
HIV primers can amplify sequences of human satellite DNA.
AIDS (London, England) 1994;8(5):709-11.
1994: Vivienne R Winrow; Silvia Ragno; Christopher J Morris; M Joseph Colston; Paolo Mascagni; F Leoni; G Gromo; Anthony R M Coates; David R Blake
Arthritogenic potential of the 65 kDa stress protein--an experimental model.
Annals of the rheumatic diseases 1994;53(3):197-201.
1993: Anthony R M Coates; T M Shinnick; R J Ellis
Chaperonin nomenclature.
Molecular microbiology 1993;8(4):787.
1993: T H Kong; Anthony R M Coates; Philip Butcher; C J Hickman; T M Shinnick
Mycobacterium tuberculosis expresses two chaperonin-60 homologs.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(7):2608-12.
1991: Lars Reinhardt Haaheim; J P Maskell; Paolo Mascagni; Anthony R M Coates
Fine molecular specificity of linear and assembled antibody binding sites in HIV-1 p24.
Scandinavian journal of immunology 1991;34(3):341-50.
1981: Anthony R M Coates; J Hewitt; B W Allen; J Ivanyi; Denis A Mitchison
Antigenic diversity of Mycobacterium tuberculosis and Mycobacterium bovis detected by means of monoclonal antibodies.
Lancet 1981;2(8239):167-9.