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Stephen Coburn

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Deborah Wenkert; Janice A Zerega; Stephen P Coburn; Karen L Ericson; Joseph H Hersh; William H McAlister; Steven Mumm; Lawrence M Ryan; Michael P Whyte
Hypophosphatasia: nonlethal disease despite skeletal presentation in utero (17 new cases and literature review).
Michael P Whyte; Deborah Wenkert; William H McAlister; M Zulf Mughal; Anthony J Freemont; Richard Whitehouse; Eileen M Baildam; Stephen P Coburn; Lawrence M Ryan; Steven Mumm
Chronic recurrent multifocal osteomyelitis mimicked in childhood hypophosphatasia.
Priscilla G Massé; Carole C Tranchant; J L Jougleux; Stephen P Coburn; David E C Cole
Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen.

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All Publications

2011: Deborah Wenkert; Janice A Zerega; Stephen P Coburn; Karen L Ericson; Joseph H Hersh; William H McAlister; Steven Mumm; Lawrence M Ryan; Michael P Whyte
Hypophosphatasia: nonlethal disease despite skeletal presentation in utero (17 new cases and literature review).
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(10):2389-98.
2009: Michael P Whyte; Deborah Wenkert; William H McAlister; M Zulf Mughal; Anthony J Freemont; Richard Whitehouse; Eileen M Baildam; Stephen P Coburn; Lawrence M Ryan; Steven Mumm
Chronic recurrent multifocal osteomyelitis mimicked in childhood hypophosphatasia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(8):1493-505.
2008: Priscilla G Massé; Carole C Tranchant; J L Jougleux; Stephen P Coburn; David E C Cole
Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 2008;21(2):117-28.
2007: Richard A Cahill; Deborah Wenkert; Sharon A Perlman; Ann Steele; Stephen P Coburn; William H McAlister; Steven Mumm; Michael P Whyte
Infantile hypophosphatasia: transplantation therapy trial using bone fragments and cultured osteoblasts.
The Journal of clinical endocrinology and metabolism 2007;92(8):2923-30.
2005: Theo van den Bos; G Handoko; Anneke Niehof; Lawrence M Ryan; Stephen P Coburn; Michael P Whyte; Wouter Beertsen
Cementum and dentin in hypophosphatasia.
Journal of dental research 2005;84(11):1021-5.
2005: Karen L Ericson; J Dennis Mahuren; Yvonne M Zubovic; Stephen P Coburn
Use of chlorite to improve HPLC detection of pyridoxal 5'-phosphate.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;823(2):218-20.
2005: P G Masse; Juliana Dosy; David E C Cole; J Evrovski; J Dennis Mahuren; Stephen P Coburn
Elevation of plasma homocysteine in natural menopause can not be explained by a lack of vitamin coenzyme availability: relevance to the risk of cardiovascular disease.
The journal of nutrition, health & aging 2005;9(1):59-64.
2003: Michael P Whyte; Joanne Kurtzberg; William H McAlister; Steven Mumm; Michelle N Podgornik; Stephen P Coburn; Lawrence M Ryan; Cindy R Miller; Gary S Gottesman; Alan K Smith; Judy Douville; Barbara Waters-Pick; R Douglas Armstrong; Paul L Martin
Marrow cell transplantation for infantile hypophosphatasia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(4):624-36.
2003: Stephen P Coburn; Andrzej Slominski; J Dennis Mahuren; Jacobo Wortsman; Lovisa Hessle; José Luis Millan
Cutaneous metabolism of vitamin B-6.
The Journal of investigative dermatology 2003;120(2):292-300.
2003: Stephen P Coburn; Douglas W Townsend; Karen L Ericson; Robert D Reynolds; Paula J Ziegler; David L Costill; J Dennis Mahuren; Wayne E Schaltenbrand; Thomas A Pauly; Yao Wang; William J Fink; David R Pearson; David L Hachey
Modeling short (7 hour)- and long (6 week)-term kinetics of vitamin B-6 metabolism with stable isotopes in humans.
Advances in experimental medicine and biology 2003;537():173-92.
2002: Armando Lindner; Daniel D Bankson; Catherine Stehman-Breen; J Dennis Mahuren; Stephen P Coburn
Vitamin B6 metabolism and homocysteine in end-stage renal disease and chronic renal insufficiency.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;39(1):134-45.
2002: Stephen P Coburn; Robert D Reynolds; J Dennis Mahuren; Wayne E Schaltenbrand; Yao Wang; Karen L Ericson; Michael P Whyte; Yvonne M Zubovic; Paula J Ziegler; David L Costill; William J Fink; David R Pearson; Thomas A Pauly; K George Thampy; Jacobo Wortsman
Elevated plasma 4-pyridoxic acid in renal insufficiency.
The American journal of clinical nutrition 2002;75(1):57-64.
2001: J Dennis Mahuren; Stephen P Coburn; A Slominski; Jacobo Wortsman
Microassay of phosphate provides a general method for measuring the activity of phosphatases using physiological, nonchromogenic substrates such as lysophosphatidic acid.
Analytical biochemistry 2001;298(2):241-5.
1999: Kenton Fedde; L Blair; J Silverstein; Stephen P Coburn; Lawrence M Ryan; R S Weinstein; Katrina G Waymire; Sonoko Narisawa; José Luis Millán; G R MacGregor; Michael P Whyte
Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(12):2015-26.
1999: CA Moore; Cynthia J Curry; P S Henthorn; J A Smith; J C Smith; P O'Lague; Stephen P Coburn; David D Weaver; Michael P Whyte
Mild autosomal dominant hypophosphatasia: in utero presentation in two families.
American journal of medical genetics 1999;86(5):410-5.
1999: J Dennis Mahuren; P L Dubeski; Nigel John Cook; Al L Schaefer; Stephen P Coburn
Adrenocorticotropic hormone increases hydrolysis of B-6 vitamers in swine adrenal glands.
The Journal of nutrition 1999;129(10):1905-8.
1998: Stephen P Coburn; J Dennis Mahuren; M Jain; Yvonne M Zubovic; Jacobo Wortsman
Alkaline phosphatase (EC 3.1.3.1) in serum is inhibited by physiological concentrations of inorganic phosphate.
The Journal of clinical endocrinology and metabolism 1998;83(11):3951-7.
1997: J Dennis Mahuren; Stephen P Coburn
Determination of 5-pyridoxic acid, 5-pyridoxic acid lactone, and other vitamin B6 compounds by cation-exchange high-performance liquid chromatography.
Methods in enzymology 1997;280():22-9.
1996: Priscilla G Massé; C M Rimnac; Mitsuo Yamauchi; Stephen P Coburn; Robert Rucker; David S Howell; A L Boskey
Pyridoxine deficiency affects biomechanical properties of chick tibial bone.
Bone 1996;18(6):567-74.
1996: P L Dubeski; FN Owens; W O Song; Stephen P Coburn; J Dennis Mahuren
Effects of B vitamin injections on plasma B vitamin concentrations of feed-restricted beef calves infected with bovine herpesvirus-1.
Journal of animal science 1996;74(6):1358-66.
1996: Stephen P Coburn
Modeling vitamin B6 metabolism.
Advances in food and nutrition research 1996;40():107-32.
1995: Stephen P Coburn; K G Thampy; Helen W Lane; P S Conn; P J Ziegler; David L Costill; J Dennis Mahuren; William J Fink; D R Pearson; W E Schaltenbrand
Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest.
The American journal of clinical nutrition 1995;62(5):979-83.
1995: M C Schaeffer; D Gretz; J Dennis Mahuren; Stephen P Coburn
Tissue B-6 vitamer concentrations in rats fed excess vitamin B-6.
The Journal of nutrition 1995;125(9):2370-8.
1995: Katrina G Waymire; J Dennis Mahuren; J M Jaje; Tomás R Guilarte; Stephen P Coburn; Grant R MacGregor
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.
Nature genetics 1995;11(1):45-51.
1995: Michael P Whyte; M Landt; L M Ryan; R A Mulivor; Paula S Henthorn; Kenton Fedde; J Dennis Mahuren; Stephen P Coburn
Alkaline phosphatase: placental and tissue-nonspecific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5'-phosphate. Substrate accumulation in carriers of hypophosphatasia corrects during pregnancy.
The Journal of clinical investigation 1995;95(4):1440-5.
1995: Priscilla G Massé; Mitsuo Yamauchi; J Dennis Mahuren; Stephen P Coburn; O E Muniz; David S Howell
Connective tissue integrity is lost in vitamin B-6-deficient chicks.
The Journal of nutrition 1995;125(1):26-34.
1994: Stephen P Coburn
A critical review of minimal vitamin B6 requirements for growth in various species with a proposed method of calculation.
Vitamins and hormones 1994;48():259-300.
1992: Stephen P Coburn; J Dennis Mahuren; T A Pauly; K L Ericson; D W Townsend
Alkaline phosphatase activity and pyridoxal phosphate concentrations in the milk of various species.
The Journal of nutrition 1992;122(12):2348-53.
1992: Steven Schenker; R F Johnson; J Dennis Mahuren; George I Henderson; Stephen P Coburn
Human placental vitamin B6 (pyridoxal) transport: normal characteristics and effects of ethanol.
The American journal of physiology 1992;262(6 Pt 2):R966-74.
1992: Stephen P Coburn
Application of models to the determination of nutrient requirements: an overview.
The Journal of nutrition 1992;122(3 Suppl):687-9.
1992: Stephen P Coburn; J Dennis Mahuren; M S Kennedy; W E Schaltenbrand; D W Townsend
Metabolism of [14C]- and [32P]pyridoxal 5'-phosphate and [3H]pyridoxal administered intravenously to pigs and goats.
The Journal of nutrition 1992;122(2):393-401.
1991: Stephen P Coburn; J Dennis Mahuren; W E Schaltenbrand
Increased activity of pyridoxal kinase in tongue in Down's syndrome.
Journal of mental deficiency research 1991;35 ( Pt 6)():543-7.
1991: Stephen P Coburn; P J Ziegler; David L Costill; J Dennis Mahuren; William J Fink; W E Schaltenbrand; T A Pauly; D R Pearson; P S Conn; Tomás R Guilarte
Response of vitamin B-6 content of muscle to changes in vitamin B-6 intake in men.
The American journal of clinical nutrition 1991;53(6):1436-42.
1990: J Dennis Mahuren; Stephen P Coburn
B6 vitamers: cation exchange HPLC.
The Journal of nutritional biochemistry 1990;1(12):659-63.
1989: Stephen P Coburn; D W Townsend
Modelling vitamin B6 metabolism in rodents (review).
In vivo (Athens, Greece) 1989;3(3):215-23.
1989: Stephen P Coburn; J Dennis Mahuren; B S Wostmann; D L Snyder; D W Townsend
Role of intestinal microflora in the metabolism of vitamin B-6 and 4'-deoxypyridoxine examined using germfree guinea pigs and rats.
The Journal of nutrition 1989;119(2):181-8.
1988: Stephen P Coburn; J Dennis Mahuren; M S Kennedy; W E Schaltenbrand; D A Sampson; D K O'Connor; D L Snyder; B S Wostmann
B6 vitamer content of rat tissues measured by isotope tracer and chromatographic methods.
BioFactors (Oxford, England) 1988;1(4):307-12.
1988: Stephen P Coburn; D L Lewis; William J Fink; J Dennis Mahuren; W E Schaltenbrand; David L Costill
Human vitamin B-6 pools estimated through muscle biopsies.
The American journal of clinical nutrition 1988;48(2):291-4.
1988: Michael P Whyte; J Dennis Mahuren; Kenton Fedde; F S Cole; E R McCabe; Stephen P Coburn
Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase.
The Journal of clinical investigation 1988;81(4):1234-9.
1988: Stephen P Coburn; D W Townsend
A multicompartment model of vitamin B6 metabolism.
Progress in food & nutrition science 1988;12(3):227-42.
1987: W E Schaltenbrand; M S Kennedy; Stephen P Coburn
Low-ultraviolet "white" fluorescent lamps fail to protect pyridoxal phosphate from photolysis.
Clinical chemistry 1987;33(4):631-2.
1987: Stephen P Coburn; J Dennis Mahuren
Identification of pyridoxine 3-sulfate, pyridoxal 3-sulfate, and N-methylpyridoxine as major urinary metabolites of vitamin B6 in domestic cats.
The Journal of biological chemistry 1987;262(6):2642-4.
1986: Stephen P Coburn; J Dennis Mahuren
Cation-exchange high-performance liquid chromatographic analysis of vitamin B6.
Methods in enzymology 1986;122():102-10.
1985: W E Schaltenbrand; Stephen P Coburn
Determination of phenol and p-cresol in urine.
Clinical chemistry 1985;31(12):2042-3.
1985: D L Hachey; Stephen P Coburn; L T Brown; W F Erbelding; B DeMark; P D Klein
Quantitation of vitamin B6 in biological samples by isotope dilution mass spectrometry.
Analytical biochemistry 1985;151(1):159-68.
1985: M P Whyte; J Dennis Mahuren; L A Vrabel; Stephen P Coburn
Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism.
The Journal of clinical investigation 1985;76(2):752-6.
1984: Stephen P Coburn; J Dennis Mahuren; Tomás R Guilarte
Vitamin B-6 content of plasma of domestic animals determined by HPLC, enzymatic and radiometric microbiological methods.
The Journal of nutrition 1984;114(12):2269-73.
1984: Stephen P Coburn; J Dennis Mahuren; W F Erbelding; D W Townsend; D L Hachey; P D Klein
Measurement of vitamin B6 kinetics in vivo using chronic administration of labelled pyridoxine.
Progress in clinical and biological research 1984;144A():43-54.
1983: Stephen P Coburn; W E Schaltenbrand; J Dennis Mahuren; R J Clausman; D Townsend
Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults.
The American journal of clinical nutrition 1983;38(3):352-5.
1983: Stephen P Coburn; J Dennis Mahuren
A versatile cation-exchange procedure of measuring the seven major forms of vitamin B6 in biological samples.
Analytical biochemistry 1983;129(2):310-7.
1981: Stephen P Coburn; J Dennis Mahuren; W E Schaltenbrand; B S Wostmann; D Madsen
Effects of vitamin B-6 deficiency and 4'- deoxypyridoxine on pyridoxal phosphate concentrations, pyridoxine kinase and other aspects of metabolism in the rat.
The Journal of nutrition 1981;111(2):391-8.