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Shamshad Cockcroft

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Co-Publications
Name
14
Swigart, Philip
12
Fensome, Amanda
9
Morgan, Clive
8
Gomperts, BD
8
Ball, Andrew
7
Allen-Baume, Victoria
7
Jones, David
7
Skippen, Alison
6
Whatmore, J
6
Li, Michelle
5
Hsuan, Justin
4
Jones, David
4
Fensome-Green, Amanda
4
Carvou, Nicolas
4
O'Luanaigh, Niamh

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Publications

TOP 3
Cockcroft Shamshad; Frohman Michael
Special issue on phospholipase D.
Cockcroft Shamshad
Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases.
Kolman Pavel; Pica Angelo; Carvou Nicolas; Boyde Alan; Cockcroft Shamshad; Loesch Andrew; Pizzey Arnold; Simeoni Mariadelina; Capasso Giovambattista; Unwin Robert J
Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.

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All Publications

2009: Cockcroft Shamshad; Frohman Michael
Special issue on phospholipase D.
Biochimica et biophysica acta 2009;1791(9):837-8.
2009: Cockcroft Shamshad
Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases.
Biochimica et biophysica acta 2009;1791(9):905-12.
2009: Kolman Pavel; Pica Angelo; Carvou Nicolas; Boyde Alan; Cockcroft Shamshad; Loesch Andrew; Pizzey Arnold; Simeoni Mariadelina; Capasso Giovambattista; Unwin Robert J
Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.
American journal of physiology. Renal physiology 2009;296(5):F1227-37.
2009: Cockcroft Shamshad
Measurement of phosphatidylinositol and phosphatidylcholine binding and transfer activity of the lipid transport protein PITP.
Methods in molecular biology (Clifton, N.J.) 2009;462():363-77.
2008: Shadan Sadaf; Holic Roman; Carvou Nicolas; Ee Patrick; Li Michelle; Murray-Rust Judith; Cockcroft Shamshad
Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.
Traffic (Copenhagen, Denmark) 2008;9(10):1743-56.
2008: Cosker Katharina E; Shadan Sadaf; van Diepen Michiel; Morgan Clive; Li Michelle; Allen-Baume Victoria; Hobbs Carl; Doherty Patrick; Cockcroft Shamshad; Eickholt Britta J
Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons.
Journal of cell science 2008;121(Pt 6):796-803.
2008: Saiardi Adolfo; Cockcroft Shamshad
Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels.
Science signaling 2008;1(4):pe5.
2008: Stace Catherine; Manifava Maria; Delon Christine; Coadwell John; Cockcroft Shamshad; Ktistakis Nicholas T
PA binding of phosphatidylinositol 4-phosphate 5-kinase.
Advances in enzyme regulation 2008;48():55-72.
2007: Cockcroft Shamshad; Carvou Nicolas
Biochemical and biological functions of class I phosphatidylinositol transfer proteins.
Biochimica et biophysica acta 2007;1771(6):677-91.
2007: Fensome-Green Amanda; Stannard Naina; Li Michelle; Bolsover Stephen; Cockcroft Shamshad
Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.
Cell calcium 2007;41(2):145-53.
2007: Carvou Nicolas; Norden Anthony G W; Unwin Robert J; Cockcroft Shamshad
Signalling through phospholipase C interferes with clathrin-mediated endocytosis.
Cellular signalling 2007;19(1):42-51.
2007: Cockcroft Shamshad
Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins.
Biochemical Society symposium 2007;(74):259-71.
2006: Morgan Clive P; Allen-Baume Victoria; Radulovic Marko; Li Michelle; Skippen Alison; Cockcroft Shamshad
Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein beta lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment.
The Biochemical journal 2006;398(3):411-21.
2006: Hyvola Noora; Diao Aipo; McKenzie Eddie; Skippen Alison; Cockcroft Shamshad; Lowe Martin
Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.
The EMBO journal 2006;25(16):3750-61.
2006: Cockcroft Shamshad
The latest phospholipase C, PLCeta, is implicated in neuronal function.
Trends in biochemical sciences 2006;31(1):4-7.
2006: Fensome-Green Amanda; Cockcroft Shamshad
Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.
Methods in molecular biology (Clifton, N.J.) 2006;332():299-310.
2006: Skippen Alison; Swigart Philip; Cockcroft Shamshad
Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol-labeling protocols in permeabilized cells.
Methods in molecular biology (Clifton, N.J.) 2006;312():183-93.
2004: Hunt Alan N; Skippen Alison J; Koster Grielof; Postle Anthony D; Cockcroft Shamshad
Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.
Biochimica et biophysica acta 2004;1686(1-2):50-60.
2004: Morgan Clive P; Skippen Alison; Segui Bruno; Ball Andrew; Allen-Baume Victoria; Larijani Banafshe; Murray-Rust Judith; McDonald Neil; Sapkota Gopal; Morrice Nick; Cockcroft Shamshad
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
The Journal of biological chemistry 2004;279(45):47159-71.
2004: Morgan Clive P; Insall Robert; Haynes Lee; Cockcroft Shamshad
Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.
The Biochemical journal 2004;382(Pt 2):441-9.
2004: Pandey Vinita; Mihara Shoji; Fensome-Green Amanda; Bolsover Stephen; Cockcroft Shamshad
Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4048-58.
2004: Tilley Sarah J; Skippen Alison; Murray-Rust Judith; Swigart Philip M; Stewart Albert; Morgan Clive P; Cockcroft Shamshad; McDonald Neil Q
Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.
Structure (London, England : 1993) 2004;12(2):317-26.
2003: Larijani Banafshé; Allen-Baume Victoria; Morgan Clive P; Li Michelle; Cockcroft Shamshad
EGF regulation of PITP dynamics is blocked by inhibitors of phospholipase C and of the Ras-MAP kinase pathway.
Current biology : CB 2003;13(1):78-84.
2003: Sarri Elisabeth; Pardo Raul; Fensome-Green Amanda; Cockcroft Shamshad
Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.
The Biochemical journal 2003;369(Pt 2):319-29.
2002: Allen-Baume Victoria; Ségui Bruno; Cockcroft Shamshad
Current thoughts on the phosphatidylinositol transfer protein family.
FEBS letters 2002;531(1):74-80.
2002: O'Luanaigh Niamh; Pardo Raul; Fensome Amanda; Allen-Baume Victoria; Jones David; Holt Mark R; Cockcroft Shamshad
Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cells.
Molecular biology of the cell 2002;13(10):3730-46.
2002: Cockcroft Shamshad; Way Gemma; O'Luanaigh Niamh; Pardo Raul; Sarri Elisabeth; Fensome Amanda
Signalling role for ARF and phospholipase D in mast cell exocytosis stimulated by crosslinking of the high affinity FcepsilonR1 receptor.
Molecular immunology 2002;38(16-18):1277-82.
2002: Coburn Ronald F; Jones David H; Morgan Clive P; Baron Carl B; Cockcroft Shamshad
Spermine increases phosphatidylinositol 4,5-bisphosphate content in permeabilized and nonpermeabilized HL60 cells.
Biochimica et biophysica acta 2002;1584(1):20-30.
2002: Ségui Bruno; Allen-Baume Victoria; Cockcroft Shamshad
Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin.
The Biochemical journal 2002;366(Pt 1):23-34.
2002: Skippen Alison; Jones David H; Morgan Clive P; Li Michelle; Cockcroft Shamshad
Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells.
The Journal of biological chemistry 2002;277(8):5823-31.
2002: Kular Gursant S; Chaudhary Anu; Prestwich Glenn; Swigart Philip; Wetzker Reinhard; Cockcroft Shamshad
Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro.
Advances in enzyme regulation 2002;42():53-61.
2001: Cockcroft S
Signalling roles of mammalian phospholipase D1 and D2.
Cellular and molecular life sciences : CMLS 2001;58(11):1674-87.
2001: Bolsover S; Ibrahim O; O'luanaigh N; Williams H; Cockcroft S
Use of fluorescent Ca2+ dyes with green fluorescent protein and its variants: problems and solutions.
The Biochemical journal 2001;356(Pt 2):345-52.
2001: Cockcroft S; De Matteis M A
Inositol lipids as spatial regulators of membrane traffic.
The Journal of membrane biology 2001;180(3):187-94.
2001: Cockcroft S
Phosphatidylinositol transfer proteins couple lipid transport to phosphoinositide synthesis.
Seminars in cell & developmental biology 2001;12(2):183-91.
2001: Cockcroft S; Bi K; Ktistakis N T; Roth M G
Biological properties and measurement of phospholipase D activation by ADP-ribosylation factor (ARF).
Methods in enzymology 2001;329():355-72.
2000: Swigart P; Insall R; Wilkins A; Cockcroft S
Purification and cloning of phosphatidylinositol transfer proteins from Dictyostelium discoideum: homologues of both mammalian PITPs and Saccharomyces cerevisiae sec14p are found in the same cell.
The Biochemical journal 2000;347 Pt 3():837-43.
2000: Jones D H; Morris J B; Morgan C P; Kondo H; Irvine R F; Cockcroft S
Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment.
The Journal of biological chemistry 2000;275(18):13962-6.
2000: Way G; O'luanaigh N; Cockcroft S
Activation of exocytosis by cross-linking of the IgE receptor is dependent on ADP-ribosylation factor 1-regulated phospholipase D in RBL-2H3 mast cells: evidence that the mechanism of activation is via regulation of phosphatidylinositol 4,5-bisphosphate synthesis.
The Biochemical journal 2000;346 Pt 1():63-70.
1999: Leino L; Forbes L; Segal A; Cockcroft S
Reconstitution of GTPgammaS-induced NADPH oxidase activity in streptolysin-O-permeabilized neutrophils by specific cytosol fractions.
Biochemical and biophysical research communications 1999;265(1):29-37.
1999: Jones D; Bax B; Cockcroft S
ADP-ribosylation factor GTPases in signal transduction and membrane traffic: independent functions?
Biochemical Society transactions 1999;27(4):642-7.
1999: Phillips S E; Sha B; Topalof L; Xie Z; Alb J G; Klenchin V A; Swigart P; Cockcroft S; Martin T F; Luo M; Bankaitis V A
Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo.
Molecular cell 1999;4(2):187-97.
1999: Jones D; Morgan C; Cockcroft S
Phospholipase D and membrane traffic. Potential roles in regulated exocytosis, membrane delivery and vesicle budding.
Biochimica et biophysica acta 1999;1439(2):229-44.
1999: Whatmore J; Wiedemann C; Somerharju P; Swigart P; Cockcroft S
Resynthesis of phosphatidylinositol in permeabilized neutrophils following phospholipase Cbeta activation: transport of the intermediate, phosphatidic acid, from the plasma membrane to the endoplasmic reticulum for phosphatidylinositol resynthesis is not dependent on soluble lipid carriers or vesicular transport.
The Biochemical journal 1999;341 ( Pt 2)():435-44.
1999: Jones D H; Bax B; Fensome A; Cockcroft S
ADP ribosylation factor 1 mutants identify a phospholipase D effector region and reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I.
The Biochemical journal 1999;341 ( Pt 1)():185-92.
1999: Cockcroft S
Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic.
Chemistry and physics of lipids 1999;98(1-2):23-33.
1999: Swigart P; Cockcroft S
Measurement of inositol (poly)phosphate formation using [3H]inositol labeling protocols in permeabilized cells.
Methods in molecular biology (Clifton, N.J.) 1999;114():165-73.
1998: Norman J C; Jones D; Barry S T; Holt M R; Cockcroft S; Critchley D R
ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts.
The Journal of cell biology 1998;143(7):1981-95.
1998: Wiedemann C; Cockcroft S
The Role of Phosphatidylinositol Transfer Proteins (PITPs) in Intracellular Signalling.
Trends in endocrinology and metabolism: TEM 1998;9(8):324-8.
1998: Wiedemann C; Cockcroft S
Vesicular transport. Sticky fingers grab a lipid.
Nature 1998;394(6692):426-7.
1998: Cockcroft S
Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(5):423-32.
1998: Fensome A; Whatmore J; Morgan C; Jones D; Cockcroft S
ADP-ribosylation factor and Rho proteins mediate fMLP-dependent activation of phospholipase D in human neutrophils.
The Journal of biological chemistry 1998;273(21):13157-64.
1998: Cockcroft S
Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipases C and D.
Methods in molecular biology (Clifton, N.J.) 1998;84():185-97.
1997: Cockcroft S; Ball A; Fensome A; Hara S; Jones D; Prosser S; Swigart P
Phosphatidylinositol transfer proteins: an essential requirement in inositol lipid signalling.
Biochemical Society transactions 1997;25(4):1125-31.
1997: Allen V; Swigart P; Cheung R; Cockcroft S; Katan M
Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.
The Biochemical journal 1997;327 ( Pt 2)():545-52.
1997: Morgan C P; Sengelov H; Whatmore J; Borregaard N; Cockcroft S
ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.
The Biochemical journal 1997;325 ( Pt 3)():581-5.
1997: Kular G; Loubtchenkov M; Swigart P; Whatmore J; Ball A; Cockcroft S; Wetzker R
Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in the formylmethionyl-leucylphenylalanine-dependent production of phosphatidylinositol 3,4,5-trisphosphate in human neutrophils.
The Biochemical journal 1997;325 ( Pt 2)():299-301.
1997: Cockcroft S
Phosphatidylinositol transfer proteins: requirements in phospholipase C signaling and in regulated exocytosis.
FEBS letters 1997;410(1):44-8.
1997: Hara S; Swigart P; Jones D; Cockcroft S
The first 5 amino acids of the carboxyl terminus of phosphatidylinositol transfer protein (PITP) alpha play a critical role in inositol lipid signaling. Transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signaling.
The Journal of biological chemistry 1997;272(23):14908-13.
1997: Prosser S; Sarra R; Swigart P; Ball A; Cockcroft S
Deletion of 24 amino acids from the C-terminus of phosphatidylinositol transfer protein causes loss of phospholipase C-mediated inositol lipid signalling.
The Biochemical journal 1997;324 ( Pt 1)():19-23.
1997: Panaretou C; Domin J; Cockcroft S; Waterfield M D
Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex.
The Journal of biological chemistry 1997;272(4):2477-85.
1996: Cockcroft S
Phospholipase D: regulation by GTPases and protein kinase C and physiological relevance.
Progress in lipid research 1996;35(4):345-70.
1996: Whatmore J; Morgan C P; Cunningham E; Collison K S; Willison K R; Cockcroft S
ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells.
The Biochemical journal 1996;320 ( Pt 3)():785-94.
1996: Vinggaard A M; Jensen T; Morgan C P; Cockcroft S; Hansen H S
Didecanoyl phosphatidylcholine is a superior substrate for assaying mammalian phospholipase D.
The Biochemical journal 1996;319 ( Pt 3)():861-4.
1996: Fensome A; Cunningham E; Prosser S; Tan S K; Swigart P; Thomas G; Hsuan J; Cockcroft S
ARF and PITP restore GTP gamma S-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis.
Current biology : CB 1996;6(6):730-8.
1996: Cunningham E; Tan S K; Swigart P; Hsuan J; Bankaitis V; Cockcroft S
The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6589-93.
1996: Cockcroft S
ARF-regulated phospholipase D: a potential role in membrane traffic.
Chemistry and physics of lipids 1996;80(1-2):59-80.
1996: Cockcroft S
Phospholipid signaling in leukocytes.
Current opinion in hematology 1996;3(1):48-54.
1995: Greasley S E; Jhoti H; Teahan C; Solari R; Fensome A; Thomas G M; Cockcroft S; Bax B
The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.
Nature structural biology 1995;2(9):797-806.
1995: Cunningham E; Thomas G M; Ball A; Hiles I; Cockcroft S
Phosphatidylinositol transfer protein dictates the rate of inositol trisphosphate production by promoting the synthesis of PIP2.
Current biology : CB 1995;5(7):775-83.
1995: Kauffmann-Zeh A; Thomas G M; Ball A; Prosser S; Cunningham E; Cockcroft S; Hsuan J J
Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling.
Science (New York, N.Y.) 1995;268(5214):1188-90.
1994: Greasley S; Jhoti H; Fensome A C; Cockcroft S; Thomas G M; Bax B
Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1.
Journal of molecular biology 1994;244(5):651-3.
1994: Whatmore J; Cronin P; Cockcroft S
ARF1-regulated phospholipase D in human neutrophils is enhanced by PMA and MgATP.
FEBS letters 1994;352(2):113-7.
1994: Fensome A; Cunningham E; Troung O; Cockcroft S
ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells.
FEBS letters 1994;349(1):34-8.
1994: Cockcroft S; Thomas G M; Fensome A; Geny B; Cunningham E; Gout I; Hiles I; Totty N F; Truong O; Hsuan J J
Phospholipase D: a downstream effector of ARF in granulocytes.
Science (New York, N.Y.) 1994;263(5146):523-6.
1994: Thomas G M; Cunningham E; Cockcroft S
Purification of phosphatidylinositol transfer protein from brain cytosol for reconstituting G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes.
Methods in enzymology 1994;238():168-81.
1994: Cockcroft S; Thomas G M; Cunningham E; Ball A
Use of cytosol-depleted HL-60 cells for reconstitution studies of G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes.
Methods in enzymology 1994;238():154-68.
1993: Thomas G M; Cunningham E; Fensome A; Ball A; Totty N F; Truong O; Hsuan J J; Cockcroft S
An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signaling.
Cell 1993;74(5):919-28.
1993: Stutchfield J; Cockcroft S
Correlation between secretion and phospholipase D activation in differentiated HL60 cells.
The Biochemical journal 1993;293 ( Pt 3)():649-55.
1993: Geny B; Fensome A; Cockcroft S
Rat brain cytosol contains a factor which reconstitutes guanine-nucleotide-binding-protein-regulated phospholipase-D activation in HL60 cells previously permeabilized with streptolysin O.
European journal of biochemistry / FEBS 1993;215(2):389-96.
1992: Cockcroft S; Thomas G M
Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.
The Biochemical journal 1992;288 ( Pt 1)():1-14.
1992: Cockcroft S
G-protein-regulated phospholipases C, D and A2-mediated signalling in neutrophils.
Biochimica et biophysica acta 1992;1113(2):135-60.
1992: Geny B; Cockcroft S
Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells.
The Biochemical journal 1992;284 ( Pt 2)():531-8.
1991: Nielson C P; Stutchfield J; Cockcroft S
Chemotactic peptide stimulation of arachidonic acid release in HL60 cells, an interaction between G protein and phospholipase C mediated signal transduction.
Biochimica et biophysica acta 1991;1095(1):83-9.
1991: Thomas G M; Geny B; Cockcroft S
Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme.
The EMBO journal 1991;10(9):2507-12.
1991: Stutchfield J; Cockcroft S
Characterization of fMet-Leu-Phe-stimulated phospholipase C in streptolysin-O-permeabilised cells.
European journal of biochemistry / FEBS 1991;197(1):119-25.
1991: Cockcroft S
Relationship between arachidonate release and exocytosis in permeabilized human neutrophils stimulated with formylmethionyl-leucyl-phenylalanine (fMetLeuPhe), guanosine 5'-[gamma-thio]triphosphate (GTP[S]) and Ca2+.
The Biochemical journal 1991;275 ( Pt 1)():127-31.
1991: Cockcroft S; Nielson C P; Stutchfield J
Is phospholipase A2 activation regulated by G-proteins?
Biochemical Society transactions 1991;19(2):333-6.
1991: Cockcroft S; Geny B; Thomas G M
Regulation of cytosolic phosphoinositide-phospholipase C by G-protein, Gp.
Biochemical Society transactions 1991;19(2):299-302.
1990: Stutchfield J; Cockcroft S
Undifferentiated HL60 cells respond to extracellular ATP and UTP by stimulating phospholipase C activation and exocytosis.
FEBS letters 1990;262(2):256-8.
1990: Cockcroft S; Bar-Sagi D
Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes.
Cellular signalling 1990;2(3):227-34.
1989: Cockcroft S; Stutchfield J
The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils.
The Biochemical journal 1989;263(3):715-23.
1989: Cockcroft S; Stutchfield J
ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C.
FEBS letters 1989;245(1-2):25-9.
1989: Geny B; Stutchfield J; Cockcroft S
Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.
Cellular signalling 1989;1(2):165-72.
1988: Cockcroft S; Stutchfield J
Effect of pertussis toxin and neomycin on G-protein-regulated polyphosphoinositide phosphodiesterase. A comparison between HL60 membranes and permeabilized HL60 cells.
The Biochemical journal 1988;256(2):343-50.
1988: Cockcroft S; Stutchfield J
G-proteins, the inositol lipid signalling pathway, and secretion.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1988;320(1199):247-65.
1988: Stutchfield J; Cockcroft S
Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.
The Biochemical journal 1988;250(2):375-82.
1987: Cockcroft S; Howell T W; Gomperts B D
Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.
The Journal of cell biology 1987;105(6 Pt 1):2745-50.
1987: Field J B; Ealey P A; Marshall N J; Cockcroft S
Thyroid-stimulating hormone stimulates increases in inositol phosphates as well as cyclic AMP in the FRTL-5 rat thyroid cell line.
The Biochemical journal 1987;247(3):519-24.
1987: Howell T W; Cockcroft S; Gomperts B D
Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.
The Journal of cell biology 1987;105(1):191-7.
1987: Gomperts B D; Cockcroft S; Howell T W; Nüsse O; Tatham P E
The dual effector system for exocytosis in mast cells: obligatory requirement for both Ca2+ and GTP.
Bioscience reports 1987;7(5):369-81.
1987: Barrowman M M; Cockcroft S; Gomperts B D
Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils.
The Journal of physiology 1987;383():115-24.
1986: Gomperts B D; Barrowman M M; Cockcroft S
Dual role for guanine nucleotides in stimulus-secretion coupling.
Federation proceedings 1986;45(7):2156-61.
1986: Barrowman M M; Cockcroft S; Gomperts B D
Potentiation and inhibition of secretion from neutrophils by phorbol ester.
FEBS letters 1986;201(1):137-42.
1986: Barrowman M M; Cockcroft S; Gomperts B D
Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils.
Nature 1986;319(6053):504-7.
1985: Segal A W; Heyworth P G; Cockcroft S; Barrowman M M
Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein.
Nature 1985;316(6028):547-9.
1985: Cockcroft S; Barrowman M M; Gomperts B D
Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils.
FEBS letters 1985;181(2):259-63.

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