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Adam Cohen
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73
Schoemaker, Rik
56
Burggraaf, Jacobus
38
van Gerven, J M A
27
Breimer, Douwe
19
Pieters, Monique
15
Pijl, Hanno
15
de Kam, Marieke
14
Kluft, Cornelis
14
Meinders, Edo
12
de Visser, Saco
11
Kemme, Michiel
11
van Griensven, JM
11
van der Post, Jeroen-Paul
10
Frölich, Marijke
9
van Haarst, Aernout
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All Publications
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2009: Zoethout Remco W M; Schoemaker Rik C; Zuurman Lineke; van Pelt Hans; Dahan Albert; Cohen Adam F; van Gerven Joop M A
Central nervous system effects of alcohol at a pseudo-steady-state concentration using alcohol clamping in healthy volunteers.
British journal of clinical pharmacology 2009;68(4):524-34.
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2009: van Haarst Aernout D; Dijkmans Anneke C; Weimann Hans-Josef; Kemme Michiel J B; Bosch Jacobus J; Schoemaker Rik C; Cohen Adam F; Burggraaf Jacobus
Clinically important interaction between tedisamil and verapamil.
Journal of clinical pharmacology 2009;49(5):560-7.
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2009: Franson Kari L; Dubois Eline A; de Kam Marieke L; Burggraaf Jacobus; Cohen Adam F
Creating a culture of thoughtful prescribing.
Medical teacher 2009;31(5):415-9.
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2008: Zoethout Remco W M; van Gerven Joop M A; Dumont Glenn J H; Paltansing Sunita; van Burgel Nathalie D; van der Linden Monique; Dahan Albert; Cohen Adam F; Schoemaker Rik C
A comparative study of two methods for attaining constant alcohol levels.
British journal of clinical pharmacology 2008;66(5):674-81.
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2008: Cohen Adam F
Methods in clinical pharmacology--a tale of two worlds.
British journal of clinical pharmacology 2008;66(5):585-7.
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2008: Liem-Moolenaar M; Cerneus D; Molloy C J; End D; Brown K H; de Kam M L; Cohen A F; van Hensbergen Y; Burggraaf J
Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.
Clinical pharmacology and therapeutics 2008;84(4):481-7.
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2008: Franson Kari L; Dubois Eline A; de Kam Marieke L; Cohen Adam F
Measuring learning from the TRC pharmacology E-Learning program.
British journal of clinical pharmacology 2008;66(1):135-41.
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2008: van Bronswijk H; Dubois E A; Pijl H; Cohen A F
[New drugs; exenatide and sitagliptin]
Nederlands tijdschrift voor geneeskunde 2008;152(15):876-9.
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2008: van Bronswijk H; Dubois E A; van Gerven J M A; Cohen A F
[New drugs; natalizumab]
Nederlands tijdschrift voor geneeskunde 2008;152(9):499-500.
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2008: van Bronswijk H; Dubois E A; van Meurs J C; Cohen A F
[New drugs; pegaptanib and ranibizumab]
Nederlands tijdschrift voor geneeskunde 2008;152(2):82-4.
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2008: de Haas S L; de Visser S J; van der Post J P; Schoemaker R C; van Dyck K; Murphy M G; de Smet M; Vessey L K; Ramakrishnan R; Xue L; Cohen A F; van Gerven J M A
Pharmacodynamic and pharmacokinetic effects of MK-0343, a GABA(A) alpha2,3 subtype selective agonist, compared to lorazepam and placebo in healthy male volunteers.
Journal of psychopharmacology (Oxford, England) 2008;22(1):24-32.
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2008: Broeyer F J F; van Aken B E; Suzuki J; Kemme M J B; Schoemaker H C; Cohen A F; Mizushima Y; Burggraaf J
The pharmacokinetics and effects of a long-acting preparation of superoxide dismutase (PC-SOD) in man.
British journal of clinical pharmacology 2008;65(1):22-9.
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2007: Franson Kari L; Dubois Eline A; van Gerven Joop M A; Cohen Adam F
Development of visual pharmacology education across an integrated medical school curriculum.
Journal of visual communication in medicine 2007;30(4):156-61.
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2007: van Bronswijk H; Dubois E A; Osanto S; Cohen A F
[New drugs; sunitinib and sorafenib]
Nederlands tijdschrift voor geneeskunde 2007;151(52):2888-90.
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2007: van Bronswijk H; Dubois E A; van Dissel J T; Cohen A F
[New drugs; daptomycin]
Nederlands tijdschrift voor geneeskunde 2007;151(50):2777-8.
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2007: van der Vorst Maria M J; Kist-van Holthe Joana E; den Hartigh Jan; van der Heijden Albert J; Cohen Adam F; Burggraaf Jacobus
Absence of tolerance and toxicity to high-dose continuous intravenous furosemide in haemodynamically unstable infants after cardiac surgery.
British journal of clinical pharmacology 2007;64(6):796-803.
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2007: Boots Isabelle; Sukhai Rám N; Klein Richard H; Holl Robert A; Wit Jan M; Cohen Adam F; Burggraaf Jacobus
Stimulation programs for pediatric drug research--do children really benefit?
European journal of pediatrics 2007;166(8):849-55.
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2007: de Haas S L; de Visser S J; van der Post J P; de Smet M; Schoemaker R C; Rijnbeek B; Cohen A F; Vega J M; Agrawal N G B; Goel T V; Simpson R C; Pearson L K; Li S; Hesney M; Murphy M G; van Gerven J M A
Pharmacodynamic and pharmacokinetic effects of TPA023, a GABA(A) alpha(2,3) subtype-selective agonist, compared to lorazepam and placebo in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2007;21(4):374-83.
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2007: Boot J D; de Kam M L; Mascelli M A; Miller B; van Wijk R Gerth; de Groot H; Cohen A F; Diamant Z
Nasal nitric oxide: longitudinal reproducibility and the effects of a nasal allergen challenge in patients with allergic rhinitis.
Allergy 2007;62(4):378-84.
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2007: Boot Johan D; de Haas Sanne; Tarasevych Svetlana; Roy Christine; Wang Lin; Amin Dilip; Cohen Judith; Sterk Peter J; Miller Barry; Paccaly Anne; Burggraaf Jacobus; Cohen Adam F; Diamant Zuzana
Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma.
American journal of respiratory and critical care medicine 2007;175(5):450-7.
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2006: van Doorn Martijn B A; Espirito Santo Sonia M; Meijer Piet; Kamerling Ingrid M; Schoemaker Rik C; Dirsch Verena; Vollmar Angelika; Haffner Thomas; Gebhardt Rolf; Cohen Adam F; Princen Hans M; Burggraaf Jacobus
Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects.
The American journal of clinical nutrition 2006;84(6):1324-9.
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2006: Rad M; Hümpel M; Schaefer O; Schoemaker R C; Schleuning W-D; Cohen A F; Burggraaf J
Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women.
British journal of clinical pharmacology 2006;62(3):288-96.
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2006: Twiss I M; van den Berk A H M; de Kam M L; Bosch J J; Cohen A F; Vermeij P; Burggraaf J
A comparison of the gastrointestinal effects of the nitrogen-containing bisphosphonates pamidronate, alendronate, and olpadronate in humans.
Journal of clinical pharmacology 2006;46(4):483-7.
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2005: Boot J D; Tarasevych S; Sterk P J; Schoemaker R C; Wang L; Amin D; Cohen A F; Diamant Z
Reversal of the late asthmatic response increases exhaled nitric oxide.
Respiratory medicine 2005;99(12):1591-4.
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2005: van Doorn Martijn B A; Burggraaf Jacobus; van Dam Tijtje; Eerenberg Anke; Levi Marcel; Hack Cornelis E; Schoemaker Rik C; Cohen Adam F; Nuijens Jan
A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema.
The Journal of allergy and clinical immunology 2005;116(4):876-83.
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2005: van der Post J P; de Visser S J; de Kam M L; Woelfler M; Hilt D C; Vornov J; Burak E S; Bortey E; Slusher B S; Limsakun T; Cohen A F; van Gerven J M A
The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693.
British journal of clinical pharmacology 2005;60(2):128-36.
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2005: Dumont G J H; de Visser S J; Cohen A F; van Gerven J M A;
Biomarkers for the effects of selective serotonin reuptake inhibitors (SSRIs) in healthy subjects.
British journal of clinical pharmacology 2005;59(5):495-510.
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2005: Cohen Judith; Burggraaf Jacobus; Schoemaker Rik C; Sterk Peter J; Cohen Adam F; Diamant Zuzana
Relationship between airway responsiveness to neurokinin A and methacholine in asthma.
Pulmonary pharmacology & therapeutics 2005;18(3):171-6.
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2004: Buijs M M; Romijn J A; Burggraaf J; de Kam M L; Frölich M; Ackermans M T; Sauerwein H P; Cohen A F; Meinders A E; Pijl H
Glucose homeostasis in abdominal obesity: hepatic hyperresponsiveness to growth hormone action.
American journal of physiology. Endocrinology and metabolism 2004;287(1):E63-8.
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2004: van der Post J P; de Visser S J; Schoemaker R C; Cohen A F; van Gerven J M A
Pharmacokinetic/pharmacodynamic assessment of tolerance to central nervous system effects of a 3 mg sustained release tablet of rilmenidine in hypertensive patients.
Journal of psychopharmacology (Oxford, England) 2004;18(2):221-7.
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2004: Kamerling I M C; Van Haarst A D; De Kam M L; Cohen A F; Masclee A A M; Burggraaf J
Gallbladder volume as a biomarker for the motilin effect in healthy volunteers and patients with functional dyspepsia.
Alimentary pharmacology & therapeutics 2004;19(7):797-804.
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2004: Kamerling Ingrid M C; van Haarst Aernout D; Burggraaf Jacobus; Schoemaker Rik C; de Kam Marieke L; Heinzerling Hartmut; Cohen Adam F; Masclee Ad A M
Effects of a nonpeptide motilin receptor antagonist on proximal gastric motor function.
British journal of clinical pharmacology 2004;57(4):393-401.
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2004: van der Post J; de Waal P P; de Kam M L; Cohen A F; van Gerven J M A
No evidence of the usefulness of eye blinking as a marker for central dopaminergic activity.
Journal of psychopharmacology (Oxford, England) 2004;18(1):109-14.
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2004: Gijsman H J; Cohen A F; van Gerven J M A
The application of the principles of clinical drug development to pharmacological challenge tests of the serotonergic system.
Journal of psychopharmacology (Oxford, England) 2004;18(1):7-13.
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2003: Pieters M S M; van Steveninck A F; Schoemaker R C; Kroon J M; van Gerven J M A; Cohen A F
The psychomotor effects of carbamazepine in epileptic patients and healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2003;17(3):269-72.
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2003: Rijnbeek B; de Visser S J; Franson K L; Cohen A F; van Gerven J M A
REM sleep effects as a biomarker for the effects of antidepressants in healthy volunteers.
Journal of psychopharmacology (Oxford, England) 2003;17(2):196-203.
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2003: Kamerling I M C; Burggraaf J; van Haarst A D; Oppenhuizen-Duinker M F; Schoemaker H C; Biemond I; Jones R; Heinzerling H; Cohen A F; Masclee A A M
The effect of motilin on the rectum in healthy volunteers.
British journal of clinical pharmacology 2003;55(6):538-43.
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2003: Kemme Michiel J B; vd Post Jeroen P; Schoemaker Rik C; Straub Matthias; Cohen Adam F; van Gerven Joop M A
Central nervous system effects of moxonidine experimental sustained release formulation in patients with mild to moderate essential hypertension.
British journal of clinical pharmacology 2003;55(6):518-25.
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2003: Kamerling Ingrid M C; Van Haarst Aernout D; Burggraaf Jacobus; Schoemaker Rik C; Biemond Izak; Heinzerling Hartmut; Jones Richard; Cohen Adam F; Masclee Ad A M
Motilin effects on the proximal stomach in patients with functional dyspepsia and healthy volunteers.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(5):G776-81.
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2003: Kemme Michiel J B; Burggraaf Jacobus; Schoemaker Rik C; Cohen Adam F; Kluft Cornelis; Chia Stanley; Webb David J; Newby David E
Local tissue factor pathway inhibitor release in the human forearm.
Thrombosis and haemostasis 2003;89(3):438-45.
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2003: Buijs Madelon M; Burggraaf Jacobus; Wijbrandts Carla; de Kam Marieke L; Frölich Marijke; Cohen Adam F; Romijn Johannes A; Sauerwein Hans P; Meinders A Edo; Pijl Hanno
Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism.
The American journal of clinical nutrition 2003;77(3):544-50.
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2003: Kemme Michiel J; Schoemaker Rik C; Burggraaf Jacobus; van der Linden Monique; Noordzij Marina; Moerland Matthijs; Kluft Cornelis; Cohen Adam F
Endothelial binding of recombinant tissue plasminogen activator: quantification in vivo using a recirculatory model.
Journal of pharmacokinetics and pharmacodynamics 2003;30(1):3-22.
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2003: de Visser S J; van der Post J P; de Waal P P; Cornet F; Cohen A F; van Gerven J M A
Biomarkers for the effects of benzodiazepines in healthy volunteers.
British journal of clinical pharmacology 2003;55(1):39-50.
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2002: van der Post J; Noordzij L A W; de Kam M L; Blauw G J; Cohen A F; van Gerven J M A
Evaluation of tests of central nervous system performance after hypoxemia for a model for cognitive impairment.
Journal of psychopharmacology (Oxford, England) 2002;16(4):337-43.
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2002: Kemme Michiel J B; Burggraaf Jacobus; Schoemaker Rik C; Kluft Cornelis; Cohen Adam F
Quantification of heparin-induced TFPI release: a maximum release at low heparin dose.
British journal of clinical pharmacology 2002;54(6):627-34.
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2002: Buijs Madelon M; Romijn Johannes A; Burggraaf Jacobus; De Kam Marieke L; Cohen Adam F; Frölich Marijke; Stellaard Frans; Meinders A Edo; Pijl Hanno
Growth hormone blunts protein oxidation and promotes protein turnover to a similar extent in abdominally obese and normal-weight women.
The Journal of clinical endocrinology and metabolism 2002;87(12):5668-74.
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2002: de Visser Saco J; van der Post Jeroen-Paul; Nanhekhan Loyd; Schoemaker Rik C; Cohen Adam F; van Gerven Joop M A
Concentration-effect relationships of two rilmenidine single-dose infusion rates in hypertensive patients.
Clinical pharmacology and therapeutics 2002;72(4):419-28.
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2002: Schoemaker Rik C; van dDer Vorst Maria M j; van Heel Isabelle Ruijs-Dudok; Cohen Adam F; Burggraaf Jacobus;
Development of an optimal furosemide infusion strategy in infants with modeling and simulation.
Clinical pharmacology and therapeutics 2002;72(4):383-90.
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2002: Faaij R A; Burggraaf J; Schoemaker R C; Van Amsterdam R G M; Cohen A F
Absence of an interaction between the synthetic pentasaccharide fondaparinux and oral warfarin.
British journal of clinical pharmacology 2002;54(3):304-8.
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2002: Kamerling I M C; van Haarst A D; Burggraaf J; de Kam M; Biemond I; Jones R; Cohen A F; Masclee A A M
Exogenous motilin affects postprandial proximal gastric motor function and visceral sensation.
Digestive diseases and sciences 2002;47(8):1732-6.
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2002: Buijs Madelon M; Burggraaf Jacobus; Langendonk Janneke G; Schoemaker Rik C; Frölich Marijke; Arndt Jan-Willem; Cohen Adam F; Romijn Johannes A; Ackermans Mariette T; Sauerwein Hans P; Meinders A Edo; Pijl Hanno
Hyposomatotropism blunts lipolysis in abdominally obese women.
The Journal of clinical endocrinology and metabolism 2002;87(8):3851-8.
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2002: van der Post J; Schram M T; Schoemaker R C; Pieters M S M; Fuseau E; Pereira A; Baggen S; Cohen A F; van Gerven J M A
CNS effects of sumatriptan and rizatriptan in healthy female volunteers.
Cephalalgia : an international journal of headache 2002;22(4):271-81.
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2002: Schoemaker Rik C; Buijs Madelon M; Pijl Hanno; Burggraaf Jacobus; Cohen Adam F
Modeling the influence of growth hormone on lipolysis.
Journal of pharmacokinetics and pharmacodynamics 2002;29(2):157-70.
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2002: Gijsman Harm J; van Gerven Joop M A; de Kam Marieke L; Schoemaker Rik C; Pieters Monique S M; Weemaes Margo; de Rijk Roel; van der Post Jeroen; Cohen Adam F
Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers.
Journal of clinical psychopharmacology 2002;22(2):183-9.
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2002: Gijsman Harm J; van Gerven Joop M A; Verkes Robbert Jan; Schoemaker Rik C; Pieters Monique S M; Pennings Ed J M; Hessing Trees J; Cohen Adam F
Saccadic peak velocity and EEG as end-points for a serotonergic challenge test.
Human psychopharmacology 2002;17(2):83-9.
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2002: Kamerling I M C; Van Haarst A D; Burggraaf J; Schoemaker H C; Biemond I; Jones R; Cohen A F; Masclee A A M
Dose-related effects of motilin on proximal gastrointestinal motility.
Alimentary pharmacology & therapeutics 2002;16(1):129-35.
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2002: Ollier Céline; Faaij Richard A; Santoni Alix; Duvauchelle Thierry; van Haard Paul M M; Schoemaker Rik C; Cohen Adam F; de Greef Rik; Burggraaf Jacobus
Absence of interaction of fondaparinux sodium with aspirin and piroxicam in healthy male volunteers.
Clinical pharmacokinetics 2002;41 Suppl 2():31-7.
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2002: Faaij Richard A; Burggraaf Jacobus; Schoemaker Rik C; de Greef Rik; Cohen Adam F
The synthetic pentasaccharide fondaparinux sodium does not interact with oral warfarin.
Clinical pharmacokinetics 2002;41 Suppl 2():27-9.
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2001: Pijl H; de Meijer P H; Langius J; Coenegracht C I; van den Berk A H; Chandie Shaw P K; Boom H; Schoemaker R C; Cohen A F; Burggraaf J; Meinders A E
Food choice in hyperthyroidism: potential influence of the autonomic nervous system and brain serotonin precursor availability.
The Journal of clinical endocrinology and metabolism 2001;86(12):5848-53.
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2001: Pijl H; Langendonk J G; Burggraaf J; Frölich M; Cohen A F; Veldhuis J D; Meinders A E
Altered neuroregulation of GH secretion in viscerally obese premenopausal women.
The Journal of clinical endocrinology and metabolism 2001;86(11):5509-15.
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2001: Kemme M J; Faaij R A; Schoemaker R C; Kluft C; Meijer P; Cohen A F; Burggraaf J
Disagreement between bedside and laboratory activated partial thromboplastin time and international normalized ratio for various novel anticoagulants.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(7):583-91.
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2001: Kemme M J; Burggraaf J; Schoemaker R C; Cohen A F
No Influence of acute hypertriglyceridemia on plasma t-PA in healthy male volunteers.
Thrombosis research 2001;103(1):9-16.
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2001: Burggraaf J; Westendorp R G; in't Veen J C; Schoemaker R C; Sterk P J; Cohen A F; Blauw G J
Cardiovascular side effects of inhaled salbutamol in hypoxic asthmatic patients.
Thorax 2001;56(7):567-9.
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2001: Burggraaf J; Tulen J H; Lalezari S; Schoemaker R C; De Meyer P H; Meinders A E; Cohen A F; Pijl H
Sympathovagal imbalance in hyperthyroidism.
American journal of physiology. Endocrinology and metabolism 2001;281(1):E190-5.
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2001: Twiss I M; Burggraaf J; Schoemaker R C; van Elburg R M; den Hartigh J; Cohen A F; Vermeij P
The sugar absorption test in the evaluation of the gastrointestinal intolerance to bisphosphonates: studies with oral pamidronate.
Clinical pharmacology and therapeutics 2001;69(6):431-7.
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2001: de Visser S J; van Gerven J M; Schoemaker R C; Cohen A F
Concentration-effect relationships of two infusion rates of the imidazoline antihypertensive agent rilmenidine for blood pressure and development of side-effects in healthy subjects.
British journal of clinical pharmacology 2001;51(5):423-8.
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2001: van der Vorst M M; Ruys-Dudok van Heel I; Kist-van Holthe J E; den Hartigh J; Schoemaker R C; Cohen A F; Burggraaf J
Continuous intravenous furosemide in haemodynamically unstable children after cardiac surgery.
Intensive care medicine 2001;27(4):711-5.
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2001: Faaij R A; van Griensven J M; Schoemaker R C; Goggin T; Guenzi A; Kroon J M; Burggraaf J; Cohen A F
The effect of warfarin on the pharmacokinetics and pharmacodynamics of napsagatran in healthy male volunteers.
European journal of clinical pharmacology 2001;57(1):25-9.
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2001: Burggraaf J; Lalezari S; Emeis J J; Vischer U M; de Meyer P H; Pijl H; Cohen A F
Endothelial function in patients with hyperthyroidism before and after treatment with propranolol and thiamazol.
Thyroid : official journal of the American Thyroid Association 2001;11(2):153-60.
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2001: de Visser S J; van der Post J; Pieters M S; Cohen A F; van Gerven J M
Biomarkers for the effects of antipsychotic drugs in healthy volunteers.
British journal of clinical pharmacology 2001;51(2):119-32.
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2001: Verkes R J; Gijsman H J; Pieters M S; Schoemaker R C; de Visser S; Kuijpers M; Pennings E J; de Bruin D; Van de Wijngaart G; Van Gerven J M; Cohen A F
Cognitive performance and serotonergic function in users of ecstasy.
Psychopharmacology 2001;153(2):196-202.
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2001: Langendonk J G; Veldhuis J D; Burggraaf J; Schoemaker R C; Cohen A F; Meinders A E; Pijl H
Estimation of growth hormone secretion rate: impact of kinetic assumptions intrinsic to the analytical approach.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(1):R225-32.
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2000: Burggraaf J; Kemme M J; Muller L M; Schoemaker R C; Cohen A F
The influence of the hand circulation on the assessment of venous distensibility of the human forearm with venous occlusion plethysmography.
British journal of clinical pharmacology 2000;50(6):621-3.
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2000: Kemme M J; Burggraaf J; Schoemaker R C; Cohen A F; Blauw G J
No evidence for functional involvement of 5-HT2B receptors in serotonin-induced vasodilatation in the human forearm.
Journal of cardiovascular pharmacology 2000;36(6):699-703.
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2000: Burggraaf J; Schoemaker R C; Lentjes E G; Cohen A F
Sorbitol as a marker for drug-induced decreases of variable duration in liver blood flow in healthy volunteers.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;12(2):133-9.
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2000: de Roode A; van Gerven J M; Schoemaker R C; Engbers F H; Olieman W; Kroon J R; Cohen A F; Bovill J G
A comparison of the effects of propofol and midazolam on memory during two levels of sedation by using target-controlled infusion.
Anesthesia and analgesia 2000;91(5):1056-61.
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2000: Karlsson M O; Schoemaker R C; Kemp B; Cohen A F; van Gerven J M; Tuk B; Peck C C; Danhof M
A pharmacodynamic Markov mixed-effects model for the effect of temazepam on sleep.
Clinical pharmacology and therapeutics 2000;68(2):175-88.
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2000: Kemme M J; Burggraaf J; Schoemaker R C; Paulson S; Karim A; Lentjes E G; Childs A; Braeckman R A; Cohen A F
The influence of reduced liver blood flow on the pharmacokinetics and pharmacodynamics of recombinant tissue factor pathway inhibitor.
Clinical pharmacology and therapeutics 2000;67(5):504-11.
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1999: Faaij R A; Van Gerven J M; Jolivet-Landreau I; Masclee A A; Vendrig E M; Schoemaker R C; Jacobs L D; Cohen A F
Onset of action during on-demand treatment with maalox suspension or low-dose ranitidine for heartburn.
Alimentary pharmacology & therapeutics 1999;13(12):1605-10.
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1999: Langendonk J G; Meinders A E; Burggraaf J; Frölich M; Roelen C A; Schoemaker R C; Cohen A F; Pijl H
Influence of obesity and body fat distribution on growth hormone kinetics in humans.
The American journal of physiology 1999;277(5 Pt 1):E824-9.
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1999: Gijsman H J; Verkes R J; van Gerven J M; Cohen A F
MDMA study.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(4):597.
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1999: Van Haarst A D; Van Gerven J M; Cohen A F; De Smet M; Sterrett A; Birk K L; Fisher A L; De Puy M E; Goldberg M R; Musson D G
The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers.
British journal of clinical pharmacology 1999;48(2):190-6.
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1999: Cath D C; Gijsman H J; Schoemaker R C; van Griensven J M; Troost N; van Kempen G M; Cohen A F
The effect of m-CPP on tics and obsessive-compulsive phenomena in Gilles de la Tourette syndrome.
Psychopharmacology 1999;144(2):137-43.
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1999: Faaij R A; Srivastava N; van Griensven J M; Schoemaker R C; Kluft C; Burggraaf J; Cohen A F
The oral bioavailability of pentosan polysulphate sodium in healthy volunteers.
European journal of clinical pharmacology 1999;54(12):929-35.
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1999: van Steveninck A L; van Berckel B N; Schoemaker R C; Breimer D D; van Gerven J M; Cohen A F
The sensitivity of pharmacodynamic tests for the central nervous system effects of drugs on the effects of sleep deprivation.
Journal of psychopharmacology (Oxford, England) 1999;13(1):10-7.
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1998: van Gerven J M; Uchida E; Uchida N; Pieters M S; Meinders A J; Schoemaker R C; Nanhekhan L V; Kroon J M; de Visser S J; Altorf B; Yasuda K; Yasuhara H; Cohen A F
Pharmacodynamics and pharmacokinetics of a single oral dose of nitrazepam in healthy volunteers: an interethnic comparative study between Japanese and European volunteers.
Journal of clinical pharmacology 1998;38(12):1129-36.
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1998: van Haarst A D; van 't Klooster G A; van Gerven J M; Schoemaker R C; van Oene J C; Burggraaf J; Coene M C; Cohen A F
The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.
Clinical pharmacology and therapeutics 1998;64(5):542-6.
-
1998: Schoemaker R C; van Gerven J M; Cohen A F
Estimating potency for the Emax-model without attaining maximal effects.
Journal of pharmacokinetics and biopharmaceutics 1998;26(5):581-93.
-
1998: Boeijinga J K; van Meegen E; van den Ende R; Schook C E; Cohen A F
Lack of interaction between tramadol and coumarins.
Journal of clinical pharmacology 1998;38(10):966-70.
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1998: Burggraaf J; van Haarst A D; Fockens P; Schoemaker H C; Krauwinkel W J; Cohen A F
The gastrointestinal passage and release of beclomethasone dipropionate from oral delivery systems in ileostomy volunteers.
British journal of clinical pharmacology 1998;46(3):207-14.
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1998: Gijsman H J; Van Gerven J M; Tieleman M C; Schoemaker R C; Pieters M S; Ferrari M D; Cohen A F; Van Kempen G M
Pharmacokinetic and pharmacodynamic profile of oral and intravenous meta-chlorophenylpiperazine in healthy volunteers.
Journal of clinical psychopharmacology 1998;18(4):289-95.
-
1998: Schoemaker R C; Burggraaf J; Cohen A F
Assessment of hepatic blood flow using continuous infusion of high clearance drugs.
British journal of clinical pharmacology 1998;45(5):463-9.
-
1998: Burggraaf J; Schoemaker R C; Kroon J M; Cohen A F
The influence of nifedipine and captopril on liver blood flow in healthy subjects.
British journal of clinical pharmacology 1998;45(5):447-51.
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1998: Langendonk J G; Pijl H; Toornvliet A C; Burggraaf J; Frölich M; Schoemaker R C; Doornbos J; Cohen A F; Meinders A E
Circadian rhythm of plasma leptin levels in upper and lower body obese women: influence of body fat distribution and weight loss.
The Journal of clinical endocrinology and metabolism 1998;83(5):1706-12.
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1998: Burggraaf J; Schoemaker R C; Terpstra I J; Cohen A F
A phase I double-blind, placebo-controlled, single rising dose study to determine the safety, tolerability, and pharmacokinetics of oral YM934 in healthy male volunteers.
Journal of clinical pharmacology 1998;38(1):45-53.
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1998: van Griensven J M; Koster R W; Burggraaf J; Huisman L G; Kluft C; Kroon R; Schoemaker R C; Cohen A F
Effects of liver blood flow on the pharmacokinetics of tissue-type plasminogen activator (alteplase) during thrombolysis in patients with acute myocardial infarction.
Clinical pharmacology and therapeutics 1998;63(1):39-47.
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1997: Boeijinga J K; van Meegen E; van den Ende R; Schook C E; Cohen A F
Is there interaction between tramadol and phenprocoumon?
Lancet 1997;350(9090):1552-3.
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1997: van Gerven J M; Roncari G; Schoemaker R C; Massarella J; Keesmaat P; Kooyman H; Heizmann P; Zell M; Cohen A F; Dingemanse J
Integrated pharmacokinetics and pharmacodynamics of Ro 48-8684, a new benzodiazepine, in comparison with midazolam during first administration to healthy male subjects.
British journal of clinical pharmacology 1997;44(5):487-93.
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1997: Dingemanse J; van Gerven J M; Schoemaker R C; Roncari G; Oberyé J J; van Oostenbruggen M F; Massarella J; Segala P; Zell M; Cohen A F
Integrated pharmacokinetics and pharmacodynamics of Ro 48-6791, a new benzodiazepine, in comparison with midazolam during first administration to healthy male subjects.
British journal of clinical pharmacology 1997;44(5):477-86.
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1997: Tuk B; Oberyé J J; Pieters M S; Schoemaker R C; Kemp B; van Gerven J; Danhof M; Kamphuisen H A; Cohen A F; Breimer D D; Peck C C
Pharmacodynamics of temazepam in primary insomnia: assessment of the value of quantitative electroencephalography and saccadic eye movements in predicting improvement of sleep.
Clinical pharmacology and therapeutics 1997;62(4):444-52.
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1997: van Griensven J M; Koster R W; Hopkins G R; Beier H; Günzler W A; Kroon R; Schoemaker R C; Cohen A F
Effect of changes in liver blood flow on the pharmacokinetics of saruplase in patients with acute myocardial infarction.
Thrombosis and haemostasis 1997;78(3):1015-20.
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1997: van Steveninck A L; Wallnöfer A E; Schoemaker R C; Pieters M S; Danhof M; van Gerven J M; Cohen A F
A study of the effects of long-term use on individual sensitivity to temazepam and lorazepam in a clinical population.
British journal of clinical pharmacology 1997;44(3):267-75.
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1996: van Griensven J M; Huisman L G; Stuurman T; Dooijewaard G; Kroon R; Schoemaker R C; Kluft K; Cohen A F
Effects of increased liver blood flow on the kinetics and dynamics of recombinant tissue-type plasminogen activator.
Clinical pharmacology and therapeutics 1996;60(5):504-11.
-
1996: Burggraaf J; Schoemaker H C; Cohen A F
Assessment of changes in liver blood flow after food intake--comparison of ICG clearance and echo-Doppler.
British journal of clinical pharmacology 1996;42(4):499-502.
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1996: van Gerven J M; Schoemaker R C; Jacobs L D; Reints A; Ouwersloot-van der Meij M J; Hoedemaker H G; Cohen A F
Self-medication of a single headache episode with ketoprofen, ibuprofen or placebo, home-monitored with an electronic patient diary.
British journal of clinical pharmacology 1996;42(4):475-81.
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1996: Visser W H; Burggraaf J; Muller L M; Schoemaker R C; Fowler P A; Cohen A F; Ferrari M D
Pharmacokinetic and pharmacodynamic profiles of sumatriptan in migraine patients with headache recurrence or no response.
Clinical pharmacology and therapeutics 1996;60(4):452-60.
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1996: Schoemaker R C; Cohen A F
Estimating impossible curves using NONMEM.
British journal of clinical pharmacology 1996;42(3):283-90.
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1996: van Steveninck A L; Gieschke R; Schoemaker R C; Roncari G; Tuk B; Pieters M S; Breimer D D; Cohen A F
Pharmacokinetic and pharmacodynamic interactions of bretazenil and diazepam with alcohol.
British journal of clinical pharmacology 1996;41(6):565-73.
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1996: Kars M E; Pijl H; Cohen A F; Frölich M; Schoemaker H C; Brandenburg H C; Meinders A E
Specific stimulation of brain serotonin mediated neurotransmission by dexfenfluramine does not restore growth hormone responsiveness in obese women.
Clinical endocrinology 1996;44(5):541-6.
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1995: van Griensven J M; Jusko W J; Lemkes H H; Kroon R; Verhorst C J; Chiang S T; Cohen A F
Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.
Clinical pharmacology and therapeutics 1995;58(6):631-40.
-
1995: Pijl H; Cohen A F; Verkes R J; Koppeschaar H P; Iestra J A; Schoemaker H C; Frölich M; Onkenhout W; Meinders A E
Plasma amino acid ratios related to brain serotonin synthesis in response to food intake in bulimia nervosa.
Biological psychiatry 1995;38(10):659-68.
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1995: van Griensven J M; Burggraaf K J; Gerloff J; Günzler W A; Beier H; Kroon R; Huisman L G; Schoemaker R C; Kluft K; Cohen A F
Effects of changing liver blood flow by exercise and food on kinetics and dynamics of saruplase.
Clinical pharmacology and therapeutics 1995;57(4):381-9.
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1995: Aldenkamp A P; Baker G; Pieters M S; Schoemaker H C; Cohen A F; Schwabe S
The Neurotoxicity Scale: the validity of a patient-based scale, assessing neurotoxicity.
Epilepsy research 1995;20(3):229-39.
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1995: van Griensven J M; Schoemaker R C; Cohen A F; Luus H G; Seibert-Grafe M; Röthig H J
Pharmacokinetics, pharmacodynamics and bioavailability of the ACE inhibitor ramipril.
European journal of clinical pharmacology 1995;47(6):513-8.
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1994: Koster R W; Cohen A F; Hopkins G R; Beier H; Günzler W A; van der Wouw P A
Pharmacokinetics and pharmacodynamics of saruplase, an unglycosylated single-chain urokinase-type plasminogen activator, in patients with acute myocardial infarction.
Thrombosis and haemostasis 1994;72(5):740-4.
-
1994: van Steveninck A L; Schoemaker H C; den Hartigh J; Pieters M S; Breimer D D; Cohen A F
Effects of intravenous temazepam. II. A study of the long-term reproducibility of pharmacokinetics, pharmacodynamics, and concentration-effect parameters.
Clinical pharmacology and therapeutics 1994;55(5):546-55.
-
1994: van Steveninck A L; Schoemaker H C; den Hartigh J; Rijnkels J; Pieters M S; Breimer D D; Cohen A F
Effects of intravenous temazepam. I. Saccadic eye movements and electroencephalogram after fast and slow infusion to pseudo steady state.
Clinical pharmacology and therapeutics 1994;55(5):535-45.
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1994: Burggraaf J; Schoemaker H C; Kroon J M; Huisman L; Kluft C; Cohen A F
Influence of 1-desamino-8-D-vasopressin on endogenous fibrinolysis, haemodynamics and liver blood flow in healthy subjects.
Clinical science (London, England : 1979) 1994;86(5):497-503.
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1993: Wallnöfer A E; van Griensven J M; Schoemaker H C; Cohen A F; Lambert W; Kluft C; Meijer P; Kooistra T
Effect of isotretinoin on endogenous tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) in humans.
Thrombosis and haemostasis 1993;70(6):1005-8.
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1993: Pijl H; Koppeschaar H P; Cohen A F; Iestra J A; Schoemaker H C; Frölich M; Onkenhout W; Meinders A E
Evidence for brain serotonin-mediated control of carbohydrate consumption in normal weight and obese humans.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1993;17(9):513-20.
-
1993: De Boer A; Kluft C; Kasper F J; Kroon J M; Schoemaker H C; Breimer D D; Soons P A; Cohen A F
Interaction study between nifedipine and recombinant tissue-type plasminogen activator in healthy subjects.
British journal of clinical pharmacology 1993;36(2):99-104.
-
1993: Van Steveninck A L; Mandema J W; Tuk B; Van Dijk J G; Schoemaker H C; Danhof M; Cohen A F
A comparison of the concentration-effect relationships of midazolam for EEG-derived parameters and saccadic peak velocity.
British journal of clinical pharmacology 1993;36(2):109-15.
-
1993: de Boer A; Kluft C; Gerloff J; Dooijewaard G; Günzler W A; Beier H; van der Meer F J; Cohen A F
Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects.
Thrombosis and haemostasis 1993;70(2):320-5.
-
1993: Stiekema J C; Van Griensven J M; Van Dinther T G; Cohen A F
A cross-over comparison of the anti-clotting effects of three low molecular weight heparins and glycosaminoglycuronan.
British journal of clinical pharmacology 1993;36(1):51-6.
-
1993: Van Rooij J; Schoemaker H C; Bruno R; Reinhoudt J F; Breimer D D; Cohen A F
Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.
British journal of clinical pharmacology 1993;35(6):661-3.
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1993: Wallnöfer A E; Cohen A F
Good clinical practice: a question of balance.
British journal of clinical pharmacology 1993;35(5):449-50.
-
1993: Cohen A F; Kroon R; Schoemaker H C; Breimer D D; Van Vliet-Verbeek A; Brandenburg H C
The bioavailability of digoxin from three oral formulations measured by a specific h.p.l.c. assay.
British journal of clinical pharmacology 1993;35(2):136-42.
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1993: van Steveninck A L; Pieters M S; Schoemaker H C; Breimer D D; Cohen A F
CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.
British journal of clinical pharmacology 1993;35(2):114-20.
-
1993: Mulders T M; Venizelos V; Schoemaker R; Cohen A F; Breimer D D; Mulder G J
Characterization of glutathione conjugation in humans: stereoselectivity in plasma elimination pharmacokinetics and urinary excretion of (R)- and (S)-2-bromoisovalerylurea in healthy volunteers.
Clinical pharmacology and therapeutics 1993;53(1):49-58.
-
1993: Soons P A; Mulders T M; Uchida E; Schoemaker H C; Cohen A F; Breimer D D
Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.
European journal of clinical pharmacology 1993;44(2):163-9.
-
1993: Soons P A; Cohen A F; Breimer D D
Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.
European journal of clinical pharmacology 1993;44(2):113-20.
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1993: van Griensven J M; Seibert-Grafe M; Schoemaker H C; Frölich M; Cohen A F
The pharmacokinetic and pharmacodynamic interactions of ramipril with propranolol.
European journal of clinical pharmacology 1993;45(3):255-60.
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1993: van Steveninck A L; Gieschke R; Schoemaker H C; Pieters M S; Kroon J M; Breimer D D; Cohen A F
Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state.
Psychopharmacology 1993;110(4):471-8.
-
1992: Cohen A F; Burggraaf K; de Boer A; Kluft C
Clearance of plasminogen activator--a major determinant of plasma concentration: therapeutic and diagnostic implications.
Annals of the New York Academy of Sciences 1992;667():443-9.
-
1992: Kroon C; ten Hove W R; de Boer A; Kroon J M; van der Pol J M; Harthoorn-Lasthuizen E J; Schoemaker H C; van der Meer F J; Cohen A F
Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.
Circulation 1992;86(5):1370-5.
-
1992: de Boer A; Kluft C; Dooijewaard G; Kasper F J; Kroon J M; Breimer D D; Stiekema J C; Cohen A F
Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise.
Thrombosis and haemostasis 1992;68(5):550-5.
-
1992: van Steveninck A L; Verver S; Schoemaker H C; Pieters M S; Kroon R; Breimer D D; Cohen A F
Effects of temazepam on saccadic eye movements: concentration-effect relationships in individual volunteers.
Clinical pharmacology and therapeutics 1992;52(4):402-8.
-
1992: Krulder J W; de Boer A; van den Besselaar A M; Cohen A F; Schoemaker H C; Briët E; Meinders A E
Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.
Thrombosis and haemostasis 1992;68(1):30-2.
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1992: de Boer A; Kroon J M; Kroon C; van Vliet A; Schoemaker H C; Breimer D D; Donoghue S; Cohen A F
Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.
Thrombosis and haemostasis 1992;68(1):24-9.
-
1992: Mandema J W; Tuk B; van Steveninck A L; Breimer D D; Cohen A F; Danhof M
Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.
Clinical pharmacology and therapeutics 1992;51(6):715-28.
-
1992: Soons P A; Schoemaker H C; Cohen A F; Breimer D D
Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.
Journal of clinical pharmacology 1992;32(4):324-31.
-
1992: de Boer A; Kluft C; Kroon J M; Kasper F J; Schoemaker H C; Pruis J; Breimer D D; Soons P A; Emeis J J; Cohen A F
Liver blood flow as a major determinant of the clearance of recombinant human tissue-type plasminogen activator.
Thrombosis and haemostasis 1992;67(1):83-7.
-
1992: Pieters M S; Jennekens-Schinkel A; Schoemaker H C; Cohen A F
Self-selection for personality variables among healthy volunteers.
British journal of clinical pharmacology 1992;33(1):101-6.
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1991: Soons P A; De Boer A; Cohen A F; Breimer D D
Assessment of hepatic blood flow in healthy subjects by continuous infusion of indocyanine green.
British journal of clinical pharmacology 1991;32(6):697-704.
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1991: Soons P A; Vogels B A; Roosemalen M C; Schoemaker H C; Uchida E; Edgar B; Lundahl J; Cohen A F; Breimer D D
Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans.
Clinical pharmacology and therapeutics 1991;50(4):394-403.
-
1991: Cohen A F; Kroon R; Schoemaker R; Hoogkamer H; van Vliet A
Influence of gastric acidity on the bioavailability of digoxin.
Annals of internal medicine 1991;115(7):540-5.
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1991: de Boer A; Stiekema J C; Danhof M; van Dinther T G; Boeijinga J K; Cohen A F; Breimer D D
Studies of interaction of a low-molecular-weight heparinoid (Org 10172) with cloxacillin and ticarcillin in healthy male volunteers.
Antimicrobial agents and chemotherapy 1991;35(10):2110-5.
-
1991: Koster R W; Cohen A F; Kluft C; Kasper F J; van der Wouw P A; Weatherley B C
The pharmacokinetics of recombinant double-chain t-PA (duteplase): effects of bolus injection, infusions, and administration by weight in patients with myocardial infarction.
Clinical pharmacology and therapeutics 1991;50(3):267-77.
-
1991: van Steveninck A L; Schoemaker H C; Pieters M S; Kroon R; Breimer D D; Cohen A F
A comparison of the sensitivities of adaptive tracking, eye movement analysis and visual analog lines to the effects of incremental doses of temazepam in healthy volunteers.
Clinical pharmacology and therapeutics 1991;50(2):172-80.
-
1991: de Boer A; Danhof M; Cohen A F; Magnani H N; Breimer D D
Interaction study between Org 10172, a low molecular weight heparinoid, and acetylsalicylic acid in healthy male volunteers.
Thrombosis and haemostasis 1991;66(2):202-7.
-
1991: Kroon C; de Boer A; Kroon J M; Schoemaker H C; van den Meer F J; Cohen A F;
Influence of skinfold thickness on heparin absorption.
Lancet 1991;337(8747):945-6.
-
1991: Dooijewaard G; de Boer A; Turion P N; Cohen A F; Breimer D D; Kluft C
Physical exercise induces enhancement of urokinase-type plasminogen activator (u-PA) levels in plasma.
Thrombosis and haemostasis 1991;65(1):82-6.
-
1990: Cohen A F; van Hall M A; van Harten J; Schoemaker R C; Johansson P; Breimer D D; Visser R; Edgar B
The influence of infusion rate on the hemodynamic effects of felodipine.
Clinical pharmacology and therapeutics 1990;48(3):309-17.
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1990: Kroon C; de Boer A; Hoogkamer J F; Schoemaker H C; van der Meer E J; Edelbroek P M; Cohen A F
Detection of drug interactions with single dose acenocoumarol: new screening method?
International journal of clinical pharmacology, therapy, and toxicology 1990;28(8):355-60.
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1990: van den Berg G; van Steveninck F; Gubbens-Stibbe J M; Schoemaker H C; de Boer A G; Cohen A F
Influence of food on the bioavailability of metoprolol from an OROS system; a study in healthy volunteers.
European journal of clinical pharmacology 1990;39(3):315-6.
-
1989: Van Hoogdalem E J; Wackwitz A T; De Boer A G; Cohen A F; Breimer D D
Rate-controlled rectal absorption enhancement of cefoxitin by co-administration of sodium salicylate or sodium octanoate in healthy volunteers.
British journal of clinical pharmacology 1989;27(1):75-81.
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