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Clemens Cohen

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Luigi Villa; Peter Boor; Clemens D Cohen; Bernd Denecke; Frank Eitner; Lin Gan; Andrzej Konieczny; Uta Kunter; Matthias A Neusser; Tammo Ostendorf; Thomas Scholl; Claudia van Roeyen; Jürgen Floege
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
Claudia van Roeyen; Stephanie Zok; Peter Boor; Clemens D Cohen; Frank Eitner; Stefan Fleckenstein; Hermann-Josef Gröne; Andreas Ludwig; Yoshikuni Nagayama; Tammo Ostendorf; Jessica Pruessmeyer; Jürgen Floege
Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation.
Sonja Djudjaj; Jean-Claude Dussaule; Jürgen Floege; Dominique GUERROT; Lydia Hanssen; Monique Kerroch; Maja T Lindenmeyer; Peter Boor; Sabine Brandt; Christos Chatziantoniou; Clemens D Cohen; Annemarie Dittrich; Tammo Ostendorf; Ute Raffetseder; Cheng Zhu; Peter R Mertens
Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.

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All Publications

2013: Luigi Villa; Peter Boor; Clemens D Cohen; Bernd Denecke; Frank Eitner; Lin Gan; Andrzej Konieczny; Uta Kunter; Matthias A Neusser; Tammo Ostendorf; Thomas Scholl; Claudia van Roeyen; Jürgen Floege
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
The Journal of pathology 2013;229(5):672-84.
2013: Claudia van Roeyen; Stephanie Zok; Peter Boor; Clemens D Cohen; Frank Eitner; Stefan Fleckenstein; Hermann-Josef Gröne; Andreas Ludwig; Yoshikuni Nagayama; Tammo Ostendorf; Jessica Pruessmeyer; Jürgen Floege
Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation.
Kidney international 2013;83(2):251-63.
2012: Sonja Djudjaj; Jean-Claude Dussaule; Jürgen Floege; Dominique GUERROT; Lydia Hanssen; Monique Kerroch; Maja T Lindenmeyer; Peter Boor; Sabine Brandt; Christos Chatziantoniou; Clemens D Cohen; Annemarie Dittrich; Tammo Ostendorf; Ute Raffetseder; Cheng Zhu; Peter R Mertens
Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.
The Journal of pathology 2012;228(3):286-99.
2012: Celine C Berthier; Ramalingam Bethunaickan; Erwin P Bottinger; Clemens D Cohen; Anne Davidson; Tania Gonzalez-Rivera; Maja Lindenmeyer; Viji Nair; Meera Ramanujam; Stephan Segerer; Weijia Zhang; Matthias Kretzler
Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):988-1001.
2012: Eoin P Brennan; Clemens D Cohen; Peadar Ó Gaora; Catherine Godson; Maja T Lindenmeyer; Melissa J Morine; Helen M Roche; Sarah A Roxburgh; Denise M Sadlier; David W Walsh; Derek Brazil; Finian Martin
Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy.
Biochimica et biophysica acta 2012;1822(4):589-99.
2012: Garnet J Lau; Chao-Sheng Lo; Hasna Maachi; Viji Nair; Shyh-Jong Wu; Shao-Ling Zhang; Jian-Xin Zhu; ML Brezniceanu; Isabelle Chénier; Clemens D Cohen; Jean Ethier; Janos G Filep; Joelle Fragasso-Marquis; Nicolas Godin; Julie R Ingelfinger; Matthias Kretzler; Jean-Baptiste Lattouf; John S D Chan
Bcl-2-modifying factor induces renal proximal tubular cell apoptosis in diabetic mice.
Diabetes 2012;61(2):474-84.
2012: Norbert Braun; Clemens D Cohen; Ilka Edenhofer; Peter Fritz; Martin Kimmel; Joerg Latus; Maja T Lindenmeyer; Fabian Reimold; Seth L Alper; M Dominik Alscher; Dagmar Biegger; Rudolf P Wüthrich; Stephan Segerer
The spectrum of podoplanin expression in encapsulating peritoneal sclerosis.
PloS one 2012;7(12):e53382.
2012: Saskia F Heeringa; Clemens D Cohen
Kidney diseases caused by complement dysregulation: acquired, inherited, and still more to come.
Clinical & developmental immunology 2012;2012():695131.
2011: Thomas Fehr; Clemens D Cohen
Predicting an allograft's fate.
Kidney international 2011;80(12):1254-5.
2011: J Michelle Kahlenberg; Celine C Berthier; Clemens D Cohen; Matthias Kretzler; Seth G Thacker; Mariana J Kaplan
Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(11):6143-56.
2011: Kontheari Sen; Felix Eichinger; Ariana Gaspert; Matthias Kretzler; Maja T Lindenmeyer; Matthias A Neusser; Stephan Segerer; Clemens D Cohen
Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis.
The American journal of pathology 2011;179(4):1756-67.
2011: Carsten P Bramlage; Peter Bramlage; Clemens D Cohen; Michael Koziolek; Matthias Kretzler; Katharina Lange; Imad Maatouk; Gerhard A Müller; Holger Schmid; Katharina Ahrens; Jelena Bevanda; Björn Tampe; Frank Strutz
The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis.
Journal of nephrology 2011;24(5):647-55.
2011: Markus Gödel; Björn Hartleben; Nadja Herbach; Shuya Liu; Stefan Zschiedrich; Shun Lu; Andrea Debreczeni-Mór; Maja T Lindenmeyer; Maria Pia Rastaldi; Götz Hartleben; Thorsten Wiech; Alessia Fornoni; Robert G Nelson; Matthias Kretzler; Rüdiger Wanke; Hermann Pavenstädt; Dontscho Kerjaschki; Clemens D Cohen; Michael N Hall; Markus A Rüegg; Ken Inoki; Gerd Walz; Tobias B Huber
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
The Journal of clinical investigation 2011;121(6):2197-209.
2011: Desa Welsh-Bacic; Maja Lindenmeyer; Clemens D Cohen; Dan Draganovici; Jana Mandelbaum; Ilka Edenhofer; Urs Ziegler; Heinz Regele; Rudolf P Wüthrich; Stephan Segerer
Expression of the chemokine receptor CCR6 in human renal inflammation.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(4):1211-20.
2011: Emmanuel Letavernier; Boris Dansou; Matthias Lochner; Joëlle Perez; Agnès Bellocq; Maja T Lindenmeyer; Clemens D Cohen; Jean-Philippe Haymann; Gérard Eberl; Laurent Baud
Critical role of the calpain/calpastatin balance in acute allograft rejection.
European journal of immunology 2011;41(2):473-84.
2011: Julia Lichtnekert; Maja T Lindenmeyer; Shrikant R Mulay; Dan Muruve; Khader Valli Rupanagudi; Mi Ryu; Volker Vielhauer; Ramanjaneyulu Allam; Clemens D Cohen; Onkar P Kulkarni; Hans-Joachim Anders
Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.
PloS one 2011;6(10):e26778.
2011: Peter Y Chuang; Clemens D Cohen; Yan Dai; Helen He; Bun Jim; Matthias Kretzler; Ruijie Liu; John Cijiang He
Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus.
PloS one 2011;6(8):e23566.
2011: Christoph Etter; Ariana Gaspert; Renate Kain; Thomas Kistler; Stephan Regenass; Rudolf P Wüthrich; Clemens D Cohen
Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome.
BMC nephrology 2011;12():26.
2011: Matthias A Neusser; Maja T Lindenmeyer; Ilka Edenhofer; Stefanie Gaiser; Matthias Kretzler; Heinz Regele; Stephan Segerer; Clemens D Cohen
Intrarenal production of B-cell survival factors in human lupus nephritis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2011;24(1):98-107.
2010: Jeffrey B Hodgin; Clemens D Cohen
Experimental approaches to the human renal transcriptome.
Seminars in nephrology 2010;30(5):455-67.
2010: Matthias Kretzler; Clemens D Cohen
Integrative biology of renal disease: toward a holistic understanding of the kidney's function and failure.
Seminars in nephrology 2010;30(5):439-42.
2010: Astrid Starke; Maja T Lindenmeyer; Stephan Segerer; Matthias A Neusser; Barbara Rüsi; Daniel M Schmid; Clemens D Cohen; Rudolf P Wüthrich; Thomas Fehr; Ying Waeckerle-Men
Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses.
Kidney international 2010;78(1):38-47.
2010: Matthias A Neusser; Anna K Kraus; Heinz Regele; Clemens D Cohen; Thomas Fehr; Dontscho Kerjaschki; Rudolf P Wüthrich; Mark E T Penfold; Thomas Schall; Stephan Segerer
The chemokine receptor CXCR7 is expressed on lymphatic endothelial cells during renal allograft rejection.
Kidney international 2010;77(9):801-8.
2010: Björn Hartleben; Markus Gödel; Catherine Meyer-Schwesinger; Shuya Liu; Theresa Ulrich; Sven Köbler; Thorsten Wiech; Florian Grahammer; Sebastian J Arnold; Maja T Lindenmeyer; Clemens D Cohen; Hermann Pavenstädt; Dontscho Kerjaschki; Noboru Mizushima; Andrey S Shaw; Gerd Walz; Tobias B Huber
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.
The Journal of clinical investigation 2010;120(4):1084-96.
2010: Michael J Koziolek; Gerhard-Anton Müller; Antonia Zapf; Daniel Patschan; Holger Schmid; Clemens D Cohen; Stefan Koschnick; Radovan Vasko; Carsten Bramlage; Frank Strutz
Role of CX3C-chemokine CX3C-L/fractalkine expression in a model of slowly progressive renal failure.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(3):684-98.
2010: Matthias A Neusser; Maja T Lindenmeyer; Anton G Moll; Stephan Segerer; Ilka Edenhofer; Kontheari Sen; Daniel Stiehl; Matthias Kretzler; Hermann-Josef Gröne; Detlef Schlöndorff; Clemens D Cohen
Human nephrosclerosis triggers a hypoxia-related glomerulopathy.
The American journal of pathology 2010;176(2):594-607.
2010: Pengfei Gong; Allon Canaan; Bin Wang; Jeremy Leventhal; Alexandra Snyder; Viji Nair; Clemens D Cohen; Matthias Kretzler; Vivette D'Agati; Sherman Weissman; Michael J Ross
The ubiquitin-like protein FAT10 mediates NF-kappaB activation.
Journal of the American Society of Nephrology : JASN 2010;21(2):316-26.
2010: Carsten P Bramlage; Björn Tampe; Michael Koziolek; Imad Maatouk; Jelena Bevanda; Peter Bramlage; Katharina Ahrens; Katharina Lange; Holger Schmid; Clemens D Cohen; Matthias Kretzler; Gerhard A Müller
Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis.
BMC nephrology 2010;11():31.
2010: Heather N Reich; David Tritchler; Daniel C Cattran; Andrew M Herzenberg; Felix Eichinger; Anissa Boucherot; Anna Henger; Celine C Berthier; Viji Nair; Clemens D Cohen; James W Scholey; Matthias Kretzler
A molecular signature of proteinuria in glomerulonephritis.
PloS one 2010;5(10):e13451.
2010: Sandhya Xavier; Victoria Gilbert; Maria Pia Rastaldi; Stefanie Krick; Dmitrij Kollins; Anand Reddy; Erwin P Bottinger; Clemens D Cohen; Detlef Schlondorff
BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation.
PloS one 2010;5(9):e12995.
2010: Maja T Lindenmeyer; Felix Eichinger; Kontheari Sen; Hans-Joachim Anders; Ilka Edenhofer; Deborah Mattinzoli; Matthias Kretzler; Maria P Rastaldi; Clemens D Cohen
Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset.
PloS one 2010;5(7):e11545.
2009: Sandra Schordan; Eric Schordan; Nicole Endlich; Maja T Lindenmeyer; Catherine Meyer-Schwesinger; Tobias N Meyer; Jürgen Giebel; Clemens D Cohen; Karlhans Endlich; Martin H Maurer
Alterations of the podocyte proteome in response to high glucose concentrations.
Proteomics 2009;9(19):4519-28.
2009: Ruth Lyck; Nadine Ruderisch; Anton G Moll; Oliver Steiner; Clemens D Cohen; Britta Engelhardt; Victoria Makrides; Francois Verrey
Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(9):1491-502.
2009: Peter Boor; Frank Eitner; Clemens D Cohen; Maja T Lindenmeyer; Peter R Mertens; Tammo Ostendorf; Jürgen Floege
Patients with IgA nephropathy exhibit high systemic PDGF-DD levels.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(9):2755-62.
2009: Clemens D Cohen
Will non-coding RNAs help to decipher renal allograft failure?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(8):2325-7.
2009: Volker Vielhauer; Ramanjaneyulu Allam; Maja T Lindenmeyer; Clemens D Cohen; Dan Draganovici; Jana Mandelbaum; Nuru Eltrich; Peter J Nelson; Hans-Joachim Anders; Monika Pruenster; Antal Rot; Detlef Schlöndorff; Stephan Segerer
Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines.
The American journal of pathology 2009;175(1):119-31.
2009: Wenjun Ju; Felix Eichinger; Markus Bitzer; Jun Oh; Shannon McWeeney; Celine C Berthier; Kerby Shedden; Clemens D Cohen; Anna Henger; Stefanie Krick; Jeffrey B Kopp; Christian J Stoeckert; Steven Dikman; Bernd Schroppel; David B Thomas; Detlef Schlondorff; Matthias Kretzler; Erwin P Böttinger
Renal gene and protein expression signatures for prediction of kidney disease progression.
The American journal of pathology 2009;174(6):2073-85.
2009: Carlo Chizzolini; Clemens D Cohen; Ute Eisenberger; Thomas Hauser; Thomas Hunziker; Annette Leimgruber; Martina Pechula; Camillo Ribi; Thomas Stoll; Marten Trendelenburg
[Towards the Swiss systemic lupus erythematosus cohort study (SSCS)].
Revue médicale suisse 2009;5(199):808-11.
2009: R M Venzin; Clemens D Cohen; M Maggiorini; Rudolf P Wüthrich
Aliskiren-associated acute renal failure with hyperkalemia.
Clinical nephrology 2009;71(3):326-8.
2009: Clemens D Cohen; Matthias Kretzler
[Gene expression analyses of kidney biopsies: the European renal cDNA bank--Kröner-Fresenius biopsy bank].
Der Pathologe 2009;30(2):101-4.
2009: Tzvetanka Bondeva; Christiane Rüster; Sybille Franke; Elke Hammerschmid; Michael Klagsbrun; Clemens D Cohen; Gunter Wolf
Advanced glycation end-products suppress neuropilin-1 expression in podocytes.
Kidney international 2009;75(6):605-16.
2009: Celine C Berthier; Hongyu Zhang; MaryLee Schin; Anna Henger; Robert G Nelson; Berne Yee; Anissa Boucherot; Matthias A Neusser; Clemens D Cohen; Christin Carter-Su; Lawrence S Argetsinger; Maria Pia Rastaldi; Frank C Brosius III; Matthias Kretzler
Enhanced expression of Janus kinase-signal transducer and activator of transcription pathway members in human diabetic nephropathy.
Diabetes 2009;58(2):469-77.
2009: Anton G Moll; Maja T Lindenmeyer; Matthias Kretzler; Peter J Nelson; Ralf Zimmer; Clemens D Cohen
Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays.
PloS one 2009;4(3):e4702.
2009: Nicole Endlich; Eric Schordan; Clemens D Cohen; Matthias Kretzler; Barbara Lewko; Thilo Welsch; Wilhelm Kriz; Carol A Otey; Karlhans Endlich
Palladin is a dynamic actin-associated protein in podocytes.
Kidney international 2009;75(2):214-26.
2008: Maja T Lindenmeyer; Maria Pia Rastaldi; Masami Ikehata; Matthias A Neusser; Matthias Kretzler; Clemens D Cohen; Detlef Schlöndorff
Proteinuria and hyperglycemia induce endoplasmic reticulum stress.
Journal of the American Society of Nephrology : JASN 2008;19(11):2225-36.
2008: Matthias A Neusser; Maja T Lindenmeyer; Matthias Kretzler; Clemens D Cohen
Genomic analysis in nephrology--towards systems biology and systematic medicine?
Néphrologie & thérapeutique 2008;4(5):306-11.
2008: Stephan Segerer; F Heller; Maja T Lindenmeyer; Holger Schmid; Clemens D Cohen; D Draganovici; J Mandelbaum; Peter J Nelson; Hermann-Josef Gröne; Elisabeth F Gröne; A-M Figel; Elfriede Nössner; Detlef Schlöndorff
Compartment specific expression of dendritic cell markers in human glomerulonephritis.
Kidney international 2008;74(1):37-46.
2008: Clemens D Cohen; Maja T Lindenmeyer; Felix Eichinger; Alexander Hahn; Martin Seifert; Anton G Moll; Holger Schmid; Eva Kiss; Elisabeth Gröne; Hermann-Josef Gröne; Matthias Kretzler; Thomas Werner; Peter J Nelson
Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis.
PloS one 2008;3(8):e2937.
2008: David W Walsh; Sarah A Roxburgh; Paul McGettigan; Celine C Berthier; Desmond G Higgins; Matthias Kretzler; Clemens D Cohen; Sergio Mezzano; Derek Brazil; Finian Martin
Co-regulation of Gremlin and Notch signalling in diabetic nephropathy.
Biochimica et biophysica acta 2008;1782(1):10-21.
2007: Debra Higgins; Kuniko Kimura; Wanja M Bernhardt; Nikita Shrimanker; Yasuhiro Akai; Bernd Hohenstein; Yoshihiko Saito; Randall S Johnson; Matthias Kretzler; Clemens D Cohen; Kai-Uwe Eckardt; Masayuki Iwano; Volker H Haase
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.
The Journal of clinical investigation 2007;117(12):3810-20.
2007: Ela Karshovska; Alma Zernecke; Gueler Sevilmis; Andrea Millet; Mihail Hristov; Clemens D Cohen; Holger Schmid; Florian Krotz; Hae-Young Sohn; Volker Klauss; Christian Weber; Andreas Schober
Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2540-7.
2007: Jens Gerth; Clemens D Cohen; U Hopfer; Maja T Lindenmeyer; Manfred Sommer; Hermann-Josef Gröne; Gunter Wolf
Collagen type VIII expression in human diabetic nephropathy.
European journal of clinical investigation 2007;37(10):767-73.
2007: Michael Koziolek; H Schmid; Clemens D Cohen; Sabine Blaschke; Bernhard Hemmerlein; A Zapf; Gerhard A Müller; Frank Strutz
Potential role of fractalkine receptor expression in human renal fibrogenesis.
Kidney international 2007;72(5):599-607.
2007: Sanja Sever; Mehmet Mete Altintas; Sharif R Nankoe; Clemens C Möller; David Ko; Changli Wei; Joel Henderson; Elizabetta C del Re; Lianne Hsing; Ann H Erickson; Clemens D Cohen; Matthias Kretzler; Dontscho Kerjaschki; Alexander Rudensky; Boris Nikolic; Jochen Reiser
Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.
The Journal of clinical investigation 2007;117(8):2095-104.
2007: Maja T Lindenmeyer; Matthias Kretzler; Anissa Boucherot; Silvia Berra; Yoshinari Yasuda; Anna Henger; Felix Eichinger; Stefanie Gaiser; Holger Schmid; Maria Pia Rastaldi; Robert W Schrier; Detlef Schlöndorff; Clemens D Cohen
Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2007;18(6):1765-76.
2007: Matthias Sauter; Clemens D Cohen; Markus Wörnle; Thomas Mussack; Roland Ladurner; Thomas Sitter
ACE inhibitor and AT1-receptor blocker attenuate the production of VEGF in mesothelial cells.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2007;27(2):167-72.
2007: Florian Heller; Maja T Lindenmeyer; Clemens D Cohen; Ulrike Brandt; Dan Draganovici; Michael Fischereder; Matthias Kretzler; Hans-Joachim Anders; Thomas Sitter; Isabella Mosberger; Dontscho Kerjaschki; Heinz Regele; Detlef Schlöndorff; Stephan Segerer
The contribution of B cells to renal interstitial inflammation.
The American journal of pathology 2007;170(2):457-68.
2007: Florian Krötz; Matthias Keller; Sabine Derflinger; Holger Schmid; Torsten Gloe; Florian Bassermann; Justus Duyster; Clemens D Cohen; Christoph Schuhmann; Volker Klauss; Ulrich Pohl; Hans-Ulrich Kreider-Stempfle; Hae-Young Sohn
Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism.
Hypertension 2007;49(1):201-8.
2006: Holger Schmid; Anissa Boucherot; Yoshinari Yasuda; Anna Henger; Bodo Brunner; Felix Eichinger; Almut Nitsche; Eva Kiss; Markus Bleich; Hermann-Josef Gröne; Peter J Nelson; Detlef Schlöndorff; Clemens D Cohen; Matthias Kretzler
Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy.
Diabetes 2006;55(11):2993-3003.
2006: Mei Ding; Shiying Cui; Chengjin Li; Serge Jothy; Volker Haase; Brent M Steer; Philip A Marsden; Jeffrey Pippin; Stuart Shankland; Maria Pia Rastaldi; Clemens D Cohen; Matthias Kretzler; Susan E Quaggin
Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.
Nature medicine 2006;12(9):1081-7.
2006: Yoshinari Yasuda; Clemens D Cohen; Anna Henger; Matthias Kretzler
Gene expression profiling analysis in nephrology: towards molecular definition of renal disease.
Clinical and experimental nephrology 2006;10(2):91-8.
2006: Maria Pia Rastaldi; Silvia Armelloni; Silvia Berra; Novella Calvaresi; Alessandro Corbelli; Laura Giardino; Min Li; Guo Quin Wang; Alessandro Fornasieri; Antonello Villa; Eija Heikkila; Rabah Soliymani; Anissa Boucherot; Clemens D Cohen; Matthias Kretzler; Almut Nitsche; Maddalena Ripamonti; Antonio Malgaroli; Marzia Pesaresi; Gianluigi Forloni; Detlef Schlöndorff; Harry Holthofer; Giuseppe D'Amico
Glomerular podocytes contain neuron-like functional synaptic vesicles.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):976-8.
2006: Clemens D Cohen; Andreas Klingenhoff; Anissa Boucherot; Almut Nitsche; Anna Henger; Bodo Brunner; Holger Schmid; Monika Merkle; Moin A Saleem; Klaus-Peter Koller; Thomas Werner; Hermann-Josef Gröne; Peter J Nelson; Matthias Kretzler
Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5682-7.
2005: Holger Schmid; Hans Nitschko; Jens Gerth; Volker Kliem; Anna Henger; Clemens D Cohen; Detlef Schlöndorff; Hermann-Josef Gröne; Matthias Kretzler
Polyomavirus DNA and RNA detection in renal allograft biopsies: results from a European multicenter study.
Transplantation 2005;80(5):600-4.
2005: Clemens D Cohen; Peter P Doran; Simone M Blattner; Monika Merkle; Guo Q Wang; Holger Schmid; Peter W Mathieson; Moin A Saleem; Anna Henger; Maria Pia Rastaldi; Matthias Kretzler
Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor.
Journal of the American Society of Nephrology : JASN 2005;16(7):1958-65.
2005: Clemens D Cohen; Novella Calvaresi; Silvia Armelloni; Holger Schmid; Anna Henger; Undine Ott; Maria Pia Rastaldi; Matthias Kretzler
CD20-positive infiltrates in human membranous glomerulonephritis.
Journal of nephrology 2005;18(3):328-33.
2005: Vicente de Paulo Castro Teixeira; Simone M Blattner; Min Li; Hans-Joachim Anders; Clemens D Cohen; Ilka Edenhofer; Novella Calvaresi; Monika Merkle; Maria Pia Rastaldi; Matthias Kretzler
Functional consequences of integrin-linked kinase activation in podocyte damage.
Kidney international 2005;67(2):514-23.
2004: Hans-Joachim Anders; Emilia Belemezova; Vaclav Eis; Stephan Segerer; Volker Vielhauer; Guillermo Perez de Lema; Matthias Kretzler; Clemens D Cohen; Michael Frink; Richard Horuk; Kelly Hudkins; Charles E Alpers; Francisco Mampaso; Detlef Schlöndorff
Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice.
Journal of the American Society of Nephrology : JASN 2004;15(6):1504-13.
2004: Holger Schmid; Clemens D Cohen; Anna Henger; Detlef Schlöndorff; Matthias Kretzler
Gene expression analysis in renal biopsies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(6):1347-51.
2004: Anna Henger; Matthias Kretzler; Peter P Doran; Mahnaz Bonrouhi; Holger Schmid; Eva Kiss; Clemens D Cohen; Stephen Madden; Stefan Porubsky; Elisabeth F Gröne; Detlef Schlöndorff; Peter J Nelson; Hermann-Josef Gröne
Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression.
Kidney international 2004;65(3):904-17.
2004: Vaclav Eis; Bruno Luckow; Volker Vielhauer; Jens T Siveke; Yvonne Linde; Stephan Segerer; Guillermo Perez de Lema; Clemens D Cohen; Matthias Kretzler; Matthias Mack; Richard Horuk; Philip M Murphy; Ji-Liang Gao; Kelly Hudkins; Charles E Alpers; Hermann-Josef Gröne; Detlef Schlöndorff; Hans-Joachim Anders
Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction.
Journal of the American Society of Nephrology : JASN 2004;15(2):337-47.
2004: Stephan Segerer; Bernhard Banas; Markus Wörnle; Holger Schmid; Clemens D Cohen; Matthias Kretzler; Matthias Mack; Eva Kiss; Peter J Nelson; Detlef Schlöndorff; Hermann-Josef Gröne
CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis.
The American journal of pathology 2004;164(2):635-49.
2003: Hilke Brühl; Clemens D Cohen; Stefan Linder; Matthias Kretzler; Detlef Schlöndorff; Matthias Mack
Post-translational and cell type-specific regulation of CXCR4 expression by cytokines.
European journal of immunology 2003;33(11):3028-37.
2003: Holger Schmid; Anna Henger; Clemens D Cohen; Karin Frach; Hermann-Josef Gröne; Detlef Schlöndorff; Matthias Kretzler
Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases.
Journal of the American Society of Nephrology : JASN 2003;14(11):2958-66.
2003: Guillermo Pérez de Lema; Cor De Wit; Clemens D Cohen; Elena Nieto; Ana Molina; Bernhard Banas; Bruno Luckow; Ana B Vicente; Francisco Mampaso; Detlef Schlöndorff
Angiotensin inhibition reduces glomerular damage and renal chemokine expression in MRL/lpr mice.
The Journal of pharmacology and experimental therapeutics 2003;307(1):275-81.
2003: Holger Schmid; Clemens D Cohen; Anna Henger; Sandra Irrgang; Detlef Schlöndorff; Matthias Kretzler
Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies.
Kidney international 2003;64(1):356-60.
2003: Hans-Joachim Anders; Michael Frink; Yvonne Linde; Bernhard Banas; Markus Wörnle; Clemens D Cohen; Volker Vielhauer; Peter J Nelson; Hermann-Josef Gröne; Detlef Schlöndorff
CC chemokine ligand 5/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5658-66.
2003: Frank Eitner; Tammo Ostendorf; Matthias Kretzler; Clemens D Cohen; Ulf Eriksson; Hermann-Josef Gröne; Jürgen Floege
PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases.
Journal of the American Society of Nephrology : JASN 2003;14(5):1145-53.
2003: Hans-Joachim Anders; Bernhard Banas; Yvonne Linde; Lars Weller; Clemens D Cohen; Matthias Kretzler; Stefan Martin; Volker Vielhauer; Detlef Schlöndorff; Hermann-Josef Gröne
Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors.
Journal of the American Society of Nephrology : JASN 2003;14(2):317-26.
2003: Clemens D Cohen; Matthias Kretzler
Gene-expression analysis of microdissected renal biopsies.
Methods in molecular medicine 2003;86():285-93.
2002: Irene von Lüttichau; Roghieh Djafarzadeh; Anna Henger; Clemens D Cohen; Anke Mojaat; Marianne Jochum; Christian Ries; Peter J Nelson; Matthias Kretzler
Identification of a signal transduction pathway that regulates MMP-9 mRNA expression in glomerular injury.
Biological chemistry 2002;383(7-8):1271-5.
2002: Matthias Kretzler; Clemens D Cohen; Peter P Doran; Anna Henger; Stephen Madden; Elisabeth F Gröne; Peter J Nelson; Detlef Schlöndorff; Hermann-Josef Gröne
Repuncturing the renal biopsy: strategies for molecular diagnosis in nephrology.
Journal of the American Society of Nephrology : JASN 2002;13(7):1961-72.
2002: Thomas Ernst; Manfred Hergenhahn; Marc Kenzelmann; Clemens D Cohen; Mahnaz Bonrouhi; Annette Weninger; Ralf Klären; Elisabeth F Gröne; Manfred Wiesel; Christof Güdemann; Jens Küster; Winfried Schott; Gerd Staehler; Matthias Kretzler; Monica Hollstein; Hermann-Josef Gröne
Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue.
The American journal of pathology 2002;160(6):2169-80.
2002: Bernhard Banas; Markus Wörnle; Thorsten Berger; Peter J Nelson; Clemens D Cohen; Matthias Kretzler; Jochen Pfirstinger; Matthias Mack; Martin Lipp; Hermann-Josef Gröne; Detlef Schlöndorff
Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4301-7.
2002: Hermann-Josef Gröne; Clemens D Cohen; Elisabeth F Gröne; Claudia Schmidt; Matthias Kretzler; Detlef Schlöndorff; Peter J Nelson
Spatial and temporally restricted expression of chemokines and chemokine receptors in the developing human kidney.
Journal of the American Society of Nephrology : JASN 2002;13(4):957-67.
2002: Sonja Mandl-Weber; Clemens D Cohen; Bettina Haslinger; Matthias Kretzler; Thomas Sitter
Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells.
Kidney international 2002;61(2):570-8.
2002: Thomas Ernst; Manfred Hergenhahn; Marc Kenzelmann; Clemens D Cohen; U Ikinger; Matthias Kretzler; Monica Hollstein; Hermann-Josef Gröne
[Gene expression profiling in prostatic cancer].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2002;86():165-75.
2002: Clemens D Cohen; Matthias Kretzler
Gene expression analysis in microdissected renal tissue. Current challenges and strategies.
Nephron 2002;92(3):522-8.
2002: Hans-Joachim Anders; Volker Vielhauer; Michael Frink; Yvonne Linde; Clemens D Cohen; Simone M Blattner; Matthias Kretzler; Frank Strutz; Matthias Mack; Hermann-Josef Gröne; James Onuffer; Richard Horuk; Peter J Nelson; Detlef Schlöndorff
A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.
The Journal of clinical investigation 2002;109(2):251-9.
2002: Clemens D Cohen; Karin Frach; Detlef Schlöndorff; Matthias Kretzler
Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application.
Kidney international 2002;61(1):133-40.
2002: Clemens D Cohen; Hermann-Josef Gröne; Elisabeth F Gröne; Peter J Nelson; Detlef Schlöndorff; Matthias Kretzler
Laser microdissection and gene expression analysis on formaldehyde-fixed archival tissue.
Kidney international 2002;61(1):125-32.
2001: CM Klier; EL Nelson; Clemens D Cohen; Richard Horuk; Detlef Schlöndorff; Peter J Nelson
Chemokine-Induced secretion of gelatinase B in primary human monocytes.
Biological chemistry 2001;382(9):1405-10.
2001: Matthias Kretzler; V P Teixeira; Paul Unschuld; Clemens D Cohen; Rüdiger Wanke; I Edenhofer; Peter Mundel; Detlef Schlöndorff; H Holthöfer
Integrin-linked kinase as a candidate downstream effector in proteinuria.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1843-5.
2001: Matthias Kretzler; V P Teixeira; T Berger; Simone M Blattner; Paul Unschuld; Clemens D Cohen; Detlef Schlöndorff
Altering glomerular epithelial function in vitro using transient and stable transfection.
Journal of nephrology 2001;14(3):211-9.
2001: Hans-Joachim Anders; Volker Vielhauer; Matthias Kretzler; Clemens D Cohen; Stephan Segerer; Bruno Luckow; Lars Weller; Hermann-Josef Gröne; Detlef Schlöndorff
Chemokine and chemokine receptor expression during initiation and resolution of immune complex glomerulonephritis.
Journal of the American Society of Nephrology : JASN 2001;12(5):919-31.
2001: Bernd Schroppel; Stephan Segerer; C Keuneke; Clemens D Cohen; Detlef Schlöndorff
Hyponatremic encephalopathy after preparation for colonoscopy.
Gastrointestinal endoscopy 2001;53(4):527-9.
2001: Clemens D Cohen; C Keuneke; U Schiemann; Bernd Schroppel; S Siegert; W Rascher; M Gross; D Schlondorff
Hyponatraemia as a complication of colonoscopy.
Lancet 2001;357(9252):282-3.