FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Irun Cohen

Research Profile

Anatomy

T-Lymphocytes

Living Beings

Physiology

Lymphocyte Activation

Chemicals & Drugs

Disorders

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Sharron Bransburg-Zabary; Irun R Cohen; Gittit Dar; Dror Y Kenett; Asaf Madi; Yifat Merbl; Francisco J Quintana; Alfred I Tauber; Eshel Ben-Jacob
Individual and meta-immune networks.
Felix Mor; Irun R Cohen
Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin.
Dimitrios Karussis; Yael Keren-Zur; Salim Khoury; Naama Lanxner; Panayiota Petrou; Hagai Shor; Adi Vaknin-Dembinsky; Urania Vourka-Karussis; Julia Yachnin; Merav Amiel; Henri Atlan; Keren Baruch; Irun R Cohen; Massimo Filippi; Shalom Hajag; Ofra Haviv; Oded Abramsky; Rivka Abulafia-Lapid
T cell vaccination benefits relapsing progressive multiple sclerosis patients: a randomized, double-blind clinical trial.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Irun Cohen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Sharron Bransburg-Zabary; Irun R Cohen; Gittit Dar; Dror Y Kenett; Asaf Madi; Yifat Merbl; Francisco J Quintana; Alfred I Tauber; Eshel Ben-Jacob
Individual and meta-immune networks.
Physical biology 2013;10(2):025003.
2013: Felix Mor; Irun R Cohen
Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular albumin.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):2981-6.
2012: Dimitrios Karussis; Yael Keren-Zur; Salim Khoury; Naama Lanxner; Panayiota Petrou; Hagai Shor; Adi Vaknin-Dembinsky; Urania Vourka-Karussis; Julia Yachnin; Merav Amiel; Henri Atlan; Keren Baruch; Irun R Cohen; Massimo Filippi; Shalom Hajag; Ofra Haviv; Oded Abramsky; Rivka Abulafia-Lapid
T cell vaccination benefits relapsing progressive multiple sclerosis patients: a randomized, double-blind clinical trial.
PloS one 2012;7(12):e50478.
2012: Asaf Madi; Dror Y Kenett; Eshel Ben-Jacob; Sharron Bransburg-Zabary; Irun R Cohen
The natural autoantibody repertoire in newborns and adults: a current overview.
Advances in experimental medicine and biology 2012;750():198-212.
2012: Noam Cohen; Lea Eisenbach; Steffen Jung; Raanan Margalit; Meirav Pevsner-Fischer; Simon Yona; Irun R Cohen
Mouse dendritic cells pulsed with capsular polysaccharide induce resistance to lethal pneumococcal challenge: roles of T cells and B cells.
PloS one 2012;7(6):e39193.
2011: Ilan Volovitz; Meir Azulay; Irun R Cohen; Ofir Goldberger; Arthur Machlenkin; Yotvat Marmor; Felix Mor; Zvi Ram; Shimon Slavin; Lea Eisenbach
Split immunity: immune inhibition of rat gliomas by subcutaneous exposure to unmodified live tumor cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):5452-62.
2011: Bartlomiej Swiatczak; Maria Rescigno; Irun R Cohen
Systemic features of immune recognition in the gut.
Microbes and infection / Institut Pasteur 2011;13(12-13):983-91.
2011: Oded Vainas; David Harel; Irun R Cohen; Sol Efroni
Reactive animation: from piecemeal experimentation to reactive biological systems.
Autoimmunity 2011;44(4):271-81.
2011: Anna Nemirovsky; Yair Fisher; Rona Baron; Irun R Cohen; Alon Monsonego
Amyloid beta-HSP60 peptide conjugate vaccine treats a mouse model of Alzheimer's disease.
Vaccine 2011;29(23):4043-50.
2011: Asaf Madi; Dror Y Kenett; Sharron Bransburg-Zabary; Yifat Merbl; Francisco J Quintana; Stefano Boccaletti; Alfred I Tauber; Irun R Cohen; Eshel Ben-Jacob
Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood.
Chaos (Woodbury, N.Y.) 2011;21(1):016109.
2011: Peter H Hagedorn; Christopher M Burton; Eli Sahar; Eytan Domany; Irun R Cohen; Henrik Flyvbjerg; Martin Iversen
Integrative analysis correlates donor transcripts to recipient autoantibodies in primary graft dysfunction after lung transplantation.
Immunology 2011;132(3):394-400.
2011: Francisco J Quintana; Irun R Cohen
The HSP60 immune system network.
Trends in immunology 2011;32(2):89-95.
2011: Asaf Madi; Dror Y Kenett; Sharron Bransburg-Zabary; Yifat Merbl; Francisco J Quintana; Alfred I Tauber; Irun R Cohen; Eshel Ben-Jacob
Network theory analysis of antibody-antigen reactivity data: the immune trees at birth and adulthood.
PloS one 2011;6(3):e17445.
2011: David Margel; Meirav Pesvner-Fischer; Jack Baniel; Ofer Yossepowitch; Meirav Pevsner-Fischer; Irun R Cohen
Stress proteins and cytokines are urinary biomarkers for diagnosis and staging of bladder cancer.
European urology 2011;59(1):113-9.
2010: Ilan Volovitz; Yotvat Marmor; Felix Mor; Alexander Flügel; Francesca Odoardi; Lea Eisenbach; Irun R Cohen
T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells.
Journal of autoimmunity 2010;35(2):135-44.
2010: Orly Gershoni-Yahalom; Shimon Landes; Smadar Kleiman-Shoval; David Ben-Nathan; Michal Kam; Bat-El Lachmi; Yevgeny Khinich; Michael Simanov; Itzchak Samina; Anat Eitan; Irun R Cohen; Bracha Rager-Zisman; Angel Porgador
Chimeric vaccine composed of viral peptide and mammalian heat-shock protein 60 peptide protects against West Nile virus challenge.
Immunology 2010;130(4):527-35.
2010: Ittai Fattal; Noam Shental; Dror Mevorach; Juan-Manuel Anaya; Avi Livneh; Pnina Langevitz; Gisele Zandman-Goddard; Rachel Pauzner; Miriam Lerner; Miri Blank; Maria-Eugenia Hincapie; Uzi Gafter; Yaakov Naparstek; Yehuda Shoenfeld; Eytan Domany; Irun R Cohen
An antibody profile of systemic lupus erythematosus detected by antigen microarray.
Immunology 2010;130(3):337-43.
2010: Peter H Hagedorn; Christopher M Burton; Jørn Carlsen; Daniel Steinbrüchel; Claus B Andersen; Eli Sahar; Eytan Domany; Irun R Cohen; Henrik Flyvbjerg; Martin Iversen
Chronic rejection of a lung transplant is characterized by a profile of specific autoantibodies.
Immunology 2010;130(3):427-35.
2010: Tomer Cohen; Shmuel Jaffe Cohen; Niv Antonovsky; Irun R Cohen; Yechiel Shai
HIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferation.
PLoS pathogens 2010;6(9):e1001085.
2010: Shmuel J Cohen; Irun R Cohen; Gabriel Nussbaum
IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(1):212-21.
2009: Irun R Cohen
Biomarker vaccines.
Human vaccines 2009;5(9):637-9.
2009: Asaf Madi; Inbal Hecht; Sharron Bransburg-Zabary; Yifat Merbl; Adi Pick; Merav Zucker-Toledano; Francisco J Quintana; Alfred I Tauber; Irun R Cohen; Eshel Ben-Jacob
Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14484-9.
2009: Michal Cohen-Sfady; Meirav Pevsner-Fischer; Raanan Margalit; Irun R Cohen
Heat shock protein 60, via MyD88 innate signaling, protects B cells from apoptosis, spontaneous and induced.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):890-6.
2009: Yifat Merbl; Royi Itzchak; Tal Vider-Shalit; Yoram Louzoun; Francisco J Quintana; Ezra Vadai; Lea Eisenbach; Irun R Cohen
A systems immunology approach to the host-tumor interaction: large-scale patterns of natural autoantibodies distinguish healthy and tumor-bearing mice.
PloS one 2009;4(6):e6053.
2008: Francisco J Quintana; Mauricio F Farez; Vissia Viglietta; Antonio H Iglesias; Yifat Merbl; Guillermo Izquierdo; Miguel Lucas; Alexandre S Basso; Samia J Khoury; Claudia F Lucchinetti; Irun R Cohen; Howard L Weiner
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(48):18889-94.
2008: Volkert A L Huurman; P E van der Meide; Gaby Duinkerken; Sabine Willemen; Irun R Cohen; D Elias; Bart O Roep
Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes.
Clinical and experimental immunology 2008;152(3):488-97.
2008: Tomer Cohen; Meirav Pevsner-Fischer; Noam Cohen; Irun R Cohen; Yechiel Shai
Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor.
Biochemistry 2008;47(16):4826-33.
2008: Francisco J Quintana; Irun R Cohen
Regulatory T cells and immune computation.
European journal of immunology 2008;38(4):903-7.
2008: Noam Cohen; Michal Stolarsky-Bennun; Hila Amir-Kroll; Raanan Margalit; Gabriel Nussbaum; Michal Cohen-Sfady; Meirav Pevsner-Fischer; Mati Fridkin; Herve Bercovier; Lea Eisenbach; Steffen Jung; Irun R Cohen
Pneumococcal capsular polysaccharide is immunogenic when present on the surface of macrophages and dendritic cells: TLR4 signaling induced by a conjugate vaccine or by lipopolysaccharide is conducive.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2409-18.
2008: Francisco J Quintana; Aderet Solomon; Irun R Cohen; Gabriel Nussbaum
Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation.
PloS one 2008;3(10):e3509.
2008: Francisco J Quintana; Irun R Cohen
HSP60 speaks to the immune system in many voices.
Novartis Foundation symposium 2008;291():101-11; discussion 111-4, 137-40.
2008: Irun R Cohen; Lars Klareskog
Antiinflammatory therapy for rheumatoid arthritis?
Arthritis and rheumatism 2008;58(1):2-4.
2007: Irun R Cohen
Biomarkers, self-antigens and the immunological homunculus.
Journal of autoimmunity 2007;29(4):246-9.
2007: Kai W Wucherpfennig; Paul M Allen; Franco Celada; Irun R Cohen; Rob De Boer; K Christopher Garcia; Byron Goldstein; Ralph Greenspan; David A Hafler; Philip Hodgkin; Erik S Huseby; David C Krakauer; David Nemazee; Alan S Perelson; Clemencia Pinilla; Roland K Strong; Eli E Sercarz
Polyspecificity of T cell and B cell receptor recognition.
Seminars in immunology 2007;19(4):216-24.
2007: Alexandra Zanin-Zhorov; Guy Tal-Lapidot; Liora Cahalon; Michal Cohen-Sfady; Meirav Pevsner-Fischer; Ofer Lider; Irun R Cohen
Cutting edge: T cells respond to lipopolysaccharide innately via TLR4 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):41-4.
2007: Irun R Cohen
Real and artificial immune systems: computing the state of the body.
Nature reviews. Immunology 2007;7(7):569-74.
2007: Itamar Raz; Ann Avron; Merana Tamir; M Metzger; L Symer; Roi Eldor; Irun R Cohen; Dana Elias
Treatment of new-onset type 1 diabetes with peptide DiaPep277 is safe and associated with preserved beta-cell function: extension of a randomized, double-blind, phase II trial.
Diabetes/metabolism research and reviews 2007;23(4):292-8.
2007: Volkert A L Huurman; Katelijn Decochez; Chantal Mathieu; Irun R Cohen; Bart O Roep
Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients.
Diabetes/metabolism research and reviews 2007;23(4):269-75.
2007: Irun R Cohen; David Harel
Explaining a complex living system: dynamics, multi-scaling and emergence.
Journal of the Royal Society, Interface / the Royal Society 2007;4(13):175-82.
2007: Irun R Cohen
Modeling immune behavior for experimentalists.
Immunological reviews 2007;216():232-6.
2007: Francisco J Quintana; Doron Gerber; Itai Bloch; Irun R Cohen; Yechiel Shai
A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model.
Biochemistry 2007;46(9):2317-25.
2007: Keren Shternhall-Ron; Francisco J Quintana; Shira Perl; Irit Meivar-Levy; Iris Barshack; Irun R Cohen; Sarah Ferber
Ectopic PDX-1 expression in liver ameliorates type 1 diabetes.
Journal of autoimmunity 2007;28(2-3):134-42.
2007: Yifat Merbl; Merav Zucker-Toledano; Francisco J Quintana; Irun R Cohen
Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics.
The Journal of clinical investigation 2007;117(3):712-8.
2007: Meirav Pevsner-Fischer; Vered Morad; Michal Cohen-Sfady; Liat Rousso-Noori; Alexandra Zanin-Zhorov; Shmuel Cohen; Irun R Cohen; Dov Zipori
Toll-like receptors and their ligands control mesenchymal stem cell functions.
Blood 2007;109(4):1422-32.
2007: Itai Bloch; Francisco J Quintana; Doron Gerber; Tomer Cohen; Irun R Cohen; Yechiel Shai
T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):393-401.
2007: Sol Efroni; David Harel; Irun R Cohen
Emergent dynamics of thymocyte development and lineage determination.
PLoS computational biology 2007;3(1):e13.
2006: Hila Amir-Kroll; Luis Riveron; Marìa Elena Sarmiento; V.Gustavo Sierra; Armando Acosta; Irun R Cohen
A conjugate vaccine composed of a heat shock protein 60 T-cell epitope peptide (p458) and Neisseria meningitidis type B capsular polysaccharide.
Vaccine 2006;24(42-43):6555-63.
2006: Gabriel Nussbaum; Alexandra Zanin-Zhorov; Francisco J Quintana; Ofer Lider; Irun R Cohen
Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis.
International immunology 2006;18(10):1413-9.
2006: Francisco J Quintana; Roy Zaltzman; Rafael Fernandez-Montesinos; Juan Luis Herrera; Illana Gozes; Irun R Cohen; David Pozo Perez
NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function.
Annals of the New York Academy of Sciences 2006;1070():500-6.
2006: Irun R Cohen
Informational landscapes in art, science, and evolution.
Bulletin of mathematical biology 2006;68(5):1213-29.
2006: Alexandra Zanin-Zhorov; Liora Cahalon; Guy Tal; Raanan Margalit; Ofer Lider; Irun R Cohen
Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling.
The Journal of clinical investigation 2006;116(7):2022-32.
2006: Felix Mor; Irun R Cohen
How special is a pathogenic CNS autoantigen? Immunization to many CNS self-antigens does not induce autoimmune disease.
Journal of neuroimmunology 2006;174(1-2):3-11.
2006: Omri Snir; Gad Lavie; Anat Achiron; Ilan Bank; Taya Ben-Aharon; Benjamin Sredni; Irun R Cohen; Mathilda Mandel
G-CSF enhances the adhesion of encephalitogenic T cells to extracellular matrix components: a possible mechanism for exacerbation of multiple sclerosis.
Journal of neuroimmunology 2006;172(1-2):145-55.
2006: Ziv Frankenstein; Uri Alon; Irun R Cohen
The immune-body cytokine network defines a social architecture of cell interactions.
Biology direct 2006;1():32.
2006: Francisco J Quintana; Yifat Merbl; E Sahar; Eytan Domany; Irun R Cohen
Antigen-chip technology for accessing global information about the state of the body.
Lupus 2006;15(7):428-30.
2005: Michal Cohen-Sfady; Gabriel Nussbaum; Meirav Pevsner-Fischer; Felix Mor; Pnina Carmi; Alexandra Zanin-Zhorov; Ofer Lider; Irun R Cohen
Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3594-602.
2005: Roy Eldor; Irun R Cohen; Itamar Raz
Innovative immune-based therapeutic approaches for the treatment of type 1 diabetes mellitus.
International reviews of immunology 2005;24(5-6):327-39.
2005: Mathilda Mandel; Michael Gurevich; Gad Lavie; Irun R Cohen; Anat Achiron
Unique gene expression patterns in human T-cell lines generated from multiple sclerosis patients by stimulation with a synthetic MOG peptide.
Clinical & developmental immunology 2005;12(3):203-9.
2005: Felix Mor; Marina Izak; Irun R Cohen
Identification of aldolase as a target antigen in Alzheimer's disease.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3439-45.
2005: Francisco J Quintana; Irun R Cohen
Heat shock proteins as endogenous adjuvants in sterile and septic inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):2777-82.
2005: Francisco J Quintana; Doron Gerber; Sally C Kent; Irun R Cohen; Yechiel Shai
HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.
The Journal of clinical investigation 2005;115(8):2149-58.
2005: Alexandra Zanin-Zhorov; Guy Tal; Shoham Shivtiel; Michal Cohen; Tsvee Lapidot; Gabriel Nussbaum; Raanan Margalit; Irun R Cohen; Ofer Lider
Heat shock protein 60 activates cytokine-associated negative regulator suppressor of cytokine signaling 3 in T cells: effects on signaling, chemotaxis, and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):276-85.
2005: Doron Gerber; Francisco J Quintana; Itai Bloch; Irun R Cohen; Yechiel Shai
D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1190-2.
2005: Ory Rouvio; Tatyana Dvorkin; Hila Amir-Kroll; Danit Atias; Irun R Cohen; Bracha Rager-Zisman; Angel Porgador
Self HSP60 peptide serves as an immunogenic carrier for a CTL epitope against persistence of murine cytomegalovirus in the salivary gland.
Vaccine 2005;23(27):3508-18.
2005: Avishai Mimran; Irun R Cohen
Regulatory T cells in autoimmune diseases: anti-ergotypic T cells.
International reviews of immunology 2005;24(3-4):159-79.
2005: Avishai Mimran; Felix Mor; Francisco J Quintana; Irun R Cohen
Anti-ergotypic T cells in naïve rats.
Journal of autoimmunity 2005;24(3):191-201.
2005: Francisco J Quintana; Irun R Cohen
DNA vaccines coding for heat-shock proteins (HSPs): tools for the activation of HSP-specific regulatory T cells.
Expert opinion on biological therapy 2005;5(4):545-54.
2005: Rivka Abulafia-Lapid; Shlomo Mayan; Zvi Bentwich; Yael Keren-Zur; Julia Abramowitz; Irun R Cohen; Henri Atlan
T-cell vaccination against anti-CD4 autoimmunity in HIV-1 subtypes B and C-infected patients--an extended open trial.
Vaccine 2005;23(17-18):2149-53.
2005: Alexandra Zanin-Zhorov; Rafael Bruck; Guy Tal; Shirly Oren; Hussein Aeed; Rami Hershkoviz; Irun R Cohen; Ofer Lider
Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3227-36.
2004: Rivka Abulafia-Lapid; Zvi Bentwich; Yael Keren-Zur; Irun R Cohen; Henri Atlan
T-cell vaccination against anti-CD4 autoimmunity in HIV-1 infected patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004;31 Suppl 1():S48-54.
2004: Johannes Herkel; Na'aman Kam; Neta Erez; Avishai Mimran; Alexander Heifetz; Miriam Eisenstein; Varda Rotter; Irun R Cohen
Monoclonal antibody to a DNA-binding domain of p53 mimics charge structure of DNA: anti-idiotypes to the anti-p53 antibody are anti-DNA.
European journal of immunology 2004;34(12):3623-32.
2004: Francisco J Quintana; Pnina Carmi; Felix Mor; Irun R Cohen
Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein.
Arthritis and rheumatism 2004;50(11):3712-20.
2004: Irun R Cohen; Francisco J Quintana; Avishai Mimran
Tregs in T cell vaccination: exploring the regulation of regulation.
The Journal of clinical investigation 2004;114(9):1227-32.
2004: Anat Achiron; Gad Lavie; Irena Kishner; Yael Stern; Ida Sarova-Pinhas; T Ben-Aharon; Yoram Barak; H Raz; Mor Lavie; Tilda Barliya; Meir Faibel; Irun R Cohen; Mathilda Mandel
T cell vaccination in multiple sclerosis relapsing-remitting nonresponders patients.
Clinical immunology (Orlando, Fla.) 2004;113(2):155-60.
2004: Francisco J Quintana; Peter H Hagedorn; Gad Elizur; Yifat Merbl; Eytan Domany; Irun R Cohen
Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101 Suppl 2():14615-21.
2004: Montero Enrique; Gabriel Nussbaum; Joel F Kaye; Rolando Perez; Agustin Lage; Avraham Ben-Nun; Irun R Cohen
Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies.
Journal of autoimmunity 2004;23(1):1-7.
2004: Francisco J Quintana; Irun R Cohen
The natural autoantibody repertoire and autoimmune disease.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2004;58(5):276-81.
2004: Francisco J Quintana; Edit Buzás; Zoltan Prohaszka ; Adrienn Bíró; Judit Kocsis; George Füst; András Falus; Irun R Cohen
Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies.
Journal of autoimmunity 2004;22(4):297-305.
2004: Iris Hecht; Rami Hershkoviz; Shoham Shivtiel; Tsvee Lapidot; Irun R Cohen; Ofer Lider; Liora Cahalon
Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling.
Journal of leukocyte biology 2004;75(6):1139-46.
2004: Irun R Cohen
Thoughts on the pathogenesis of type 1 diabetes and on the arrest of autoimmune beta-cell destruction by peptide p277 vaccination.
The Israel Medical Association journal : IMAJ 2004;6(5):260-1.
2004: Felix Mor; Francisco J Quintana; Irun R Cohen
Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4618-23.
2004: Avishai Mimran; Felix Mor; Pnina Carmi; Francisco J Quintana; Varda Rotter; Irun R Cohen
DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response.
The Journal of clinical investigation 2004;113(6):924-32.
2004: Irun R Cohen; Uri Hershberg; Sorin Solomon
Antigen-receptor degeneracy and immunological paradigms.
Molecular immunology 2004;40(14-15):993-6.
2003: Sol Efroni; David Harel; Irun R Cohen
Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation.
Genome research 2003;13(11):2485-97.
2003: Francisco J Quintana; Pnina Carmi; Felix Mor; Irun R Cohen
DNA fragments of the human 60-kDa heat shock protein (HSP60) vaccinate against adjuvant arthritis: identification of a regulatory HSP60 peptide.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(7):3533-41.
2003: Francisco J Quintana; Gad Getz; Guy Hed; Eytan Domany; Irun R Cohen
Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity.
Journal of autoimmunity 2003;21(1):65-75.
2003: Alexandra Zanin-Zhorov; Gabriel Nussbaum; Suzanna Franitza; Irun R Cohen; Ofer Lider
T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1567-9.
2003: Hila Amir-Kroll; Gabriel Nussbaum; Irun R Cohen
Proteins and their derived peptides as carriers in a conjugate vaccine for Streptococcus pneumoniae: self-heat shock protein 60 and tetanus toxoid.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(12):6165-71.
2003: Rivka Abulafia-Lapid; David Gillis; Orit Yosef; Henri Atlan; Irun R Cohen
T cells and autoantibodies to human HSP70 in type 1 diabetes in children.
Journal of autoimmunity 2003;20(4):313-21.
2003: Sol Efroni; Irun R Cohen
The heuristics of biologic theory: the case of self-nonself discrimination.
Cellular immunology 2003;223(1):87-9.
2003: Yoram Louzoun; Sorin Solomon; Henri Atlan; Irun R Cohen
Proliferation and competition in discrete biological systems.
Bulletin of mathematical biology 2003;65(3):375-96.
2003: Yuval Tal; Lina Souan; Irun R Cohen; Zeev Meiner; Albert Taraboulos; Felix Mor
Complete Freund's adjuvant immunization prolongs survival in experimental prion disease in mice.
Journal of neuroscience research 2003;71(2):286-90.
2003: Francisco J Quintana; Milena Pitashny; Irun R Cohen
Experimental autoimmune myasthenia gravis in naive non-obese diabetic (NOD/LtJ) mice: susceptibility associated with natural IgG antibodies to the acetylcholine receptor.
International immunology 2003;15(1):11-6.
2003: Felix Mor; Francisco J Quintana; Avishai Mimran; Irun R Cohen
Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):628-34.
2002: Johannes Herkel; Jan-Philip Modrow; Sonja Bamberger; Stephan Kanzler; Varda Rotter; Irun R Cohen; Ansgar W Lohse
Prevalence of autoantibodies to the p53 protein in autoimmune hepatitis.
Autoimmunity 2002;35(8):493-6.
2002: Francisco J Quintana; Pnina Carmi; Irun R Cohen
DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):6030-5.
2002: Irun R Cohen
Peptide therapy for Type I diabetes: the immunological homunculus and the rationale for vaccination.
Diabetologia 2002;45(10):1468-74.
2002: Francisco J Quintana; Pnina Carmi; Felix Mor; Irun R Cohen
Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):3422-8.
2002: Sol Efroni; Irun R Cohen
Simplicity belies a complex system: a response to the minimal model of immunity of Langman and Cohn.
Cellular immunology 2002;216(1-2):23-30.
2002: G Gonzalez; Montero Enrique; Kalet Leon; Irun R Cohen; Agustin Lage
Autoimmunization to epidermal growth factor, a component of the immunological homunculus.
Autoimmunity reviews 2002;1(1-2):89-95.
2002: Felix Mor; Irun R Cohen
Propagation of lewis rat encephalitogenic T cell lines: T-cell-growth-factor is superior to recombinant IL-2.
Journal of neuroimmunology 2002;123(1-2):76-82.
2002: Felix Mor; Abraham Weinberger; Irun R Cohen
Identification of alpha-tropomyosin as a target self-antigen in Behçet's syndrome.
European journal of immunology 2002;32(2):356-65.
2001: Irun R Cohen
T-cell vaccination for autoimmune disease: a panorama.
Vaccine 2001;20(5-6):706-10.
2001: Yoram Louzoun; Henri Atlan; Irun R Cohen
Modeling the influence of TH1- and TH2-type cells in autoimmune diseases.
Journal of autoimmunity 2001;17(4):311-21.
2001: Lina Souan; Raanan Margalit; Ori Brenner; Irun R Cohen; Felix Mor
Self prion protein peptides are immunogenic in Lewis rats.
Journal of autoimmunity 2001;17(4):303-10.
2001: Itamar Raz; Dana Elias; Ann Avron; Merana Tamir; M Metzger; Irun R Cohen
Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial.
Lancet 2001;358(9295):1749-53.
2001: Francisco J Quintana; Irun R Cohen
Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice.
Journal of autoimmunity 2001;17(3):191-7.
2001: Johannes Herkel; Avishai Mimran; Neta Erez; N Kam; Ansgar W Lohse; E Märker-Hermann; Varda Rotter; Irun R Cohen
Autoimmunity to the p53 protein is a feature of systemic lupus erythematosus (SLE) related to anti-DNA antibodies.
Journal of autoimmunity 2001;17(1):63-9.
2001: Lina Souan; Yuval Tal; Y Felling; Irun R Cohen; Albert Taraboulos; Felix Mor
Modulation of proteinase-K resistant prion protein by prion peptide immunization.
European journal of immunology 2001;31(8):2338-46.
2001: Eti Yoles; Ehud Hauben; O Palgi; Evgenia Agranov; Amalia Gothilf; Avi Cohen; V Kuchroo; Irun R Cohen; Howard L Weiner; Michal Schwartz
Protective autoimmunity is a physiological response to CNS trauma.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(11):3740-8.
2001: Irun R Cohen
Antigenic mimicry, clonal selection and autoimmunity.
Journal of autoimmunity 2001;16(3):337-40.
2001: Yehuda Chowers; Ofer Lider; H Schor; Iris Barshack; R Tal; Amiram Ariel; Simon Bar-Meir; Irun R Cohen; Liora Cahalon
Disaccharides derived from heparin or heparan sulfate regulate IL-8 and IL-1 beta secretion by intestinal epithelial cells.
Gastroenterology 2001;120(2):449-59.
2000: Francisco J Quintana; A Rotem; Pnina Carmi; Irun R Cohen
Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6148-55.
2000: G Moalem; Amos Gdalyahu; Yael Shani; U Otten; P Lazarovici; Irun R Cohen; Michal Schwartz
Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity.
Journal of autoimmunity 2000;15(3):331-45.
2000: Ehud Hauben; Oleg Butovsky; Uri Nevo; Eti Yoles; G Moalem; Evgenia Agranov; Felix Mor; R Leibowitz-Amit; E Pevsner; Solange Akselrod; Michal Neeman; Irun R Cohen; Michal Schwartz
Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6421-30.
2000: G Moalem; Eti Yoles; R Leibowitz-Amit; S Muller-Gilor; Felix Mor; Irun R Cohen; Michal Schwartz
Autoimmune T cells retard the loss of function in injured rat optic nerves.
Journal of neuroimmunology 2000;106(1-2):189-97.
2000: Felix Mor; M Kantorowitz; Irun R Cohen
Selection of anti-myelin basic protein T-cell lines in the lewis rat: V-beta 8.2 dominance and conserved complementarity-determining-region-3 motifs are dependent on serine at position 78 of myelin basic protein.
Journal of neuroimmunology 2000;106(1-2):154-64.
2000: Jonathan Kipnis; Eti Yoles; Ziv Porat; A Cohen; Felix Mor; Michael Sela; Irun R Cohen; Michal Schwartz
T cell immunity to copolymer 1 confers neuroprotection on the damaged optic nerve: possible therapy for optic neuropathies.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7446-51.
2000: Irun R Cohen
Discrimination and dialogue in the immune system.
Seminars in immunology 2000;12(3):215-9; discussion 257-344.
2000: Michal Schwartz; Irun R Cohen
Autoimmunity can benefit self-maintenance.
Immunology today 2000;21(6):265-8.
2000: Johannes Herkel; N Erez-Alon; Avishai Mimran; roland wolkowicz; Alon Harmelin; P Ruiz; Varda Rotter; Irun R Cohen
Systemic lupus erythematosus in mice, spontaneous and induced, is associated with autoimmunity to the C-terminal domain of p53 that recognizes damaged DNA.
European journal of immunology 2000;30(4):977-84.
2000: Ehud Hauben; Uri Nevo; Eti Yoles; G Moalem; Evgenia Agranov; Felix Mor; Solange Akselrod; Michal Neeman; Irun R Cohen; Michal Schwartz
Autoimmune T cells as potential neuroprotective therapy for spinal cord injury.
Lancet 2000;355(9200):286-7.
2000: Rami Hershkoviz; H Schor; Amiram Ariel; Iris Hecht; Irun R Cohen; Ofer Lider; Liora Cahalon
Disaccharides generated from heparan sulphate or heparin modulate chemokine-induced T-cell adhesion to extracellular matrix.
Immunology 2000;99(1):87-93.
1999: Irun R Cohen; Michal Schwartz
Autoimmune maintenance and neuroprotection of the central nervous system.
Journal of neuroimmunology 1999;100(1-2):111-4.
1999: V Ablamunits; Francisco J Quintana; Tamar Reshef; D Elias; Irun R Cohen
Acceleration of autoimmune diabetes by cyclophosphamide is associated with an enhanced IFN-gamma secretion pathway.
Journal of autoimmunity 1999;13(4):383-92.
1999: G Moalem; Alon Monsonego; Yael Shani; Irun R Cohen; Michal Schwartz
Differential T cell response in central and peripheral nerve injury: connection with immune privilege.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(10):1207-17.
1999: Michal Schwartz; G Moalem; R Leibowitz-Amit; Irun R Cohen
Innate and adaptive immune responses can be beneficial for CNS repair.
Trends in neurosciences 1999;22(7):295-9.
1999: D Elias; Y Tikochinski; G Frankel; Irun R Cohen
Regulation of NOD mouse autoimmune diabetes by T cells that recognize a TCR CDR3 peptide.
International immunology 1999;11(6):957-66.
1999: Y Tikochinski; D Elias; Christiane Steeg; Hadar Marcus; M Kantorowitz; Tamar Reshef; V Ablamunits; Irun R Cohen; A Friedmann
A shared TCR CDR3 sequence in NOD mouse autoimmune diabetes.
International immunology 1999;11(6):951-6.
1999: Ohad Birk; S L Gur; D Elias; Raanan Margalit; Felix Mor; Pnina Carmi; J Bockova; D M Altmann; Irun R Cohen
The 60-kDa heat shock protein modulates allograft rejection.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5159-63.
1999: Rivka Abulafia-Lapid; D Elias; I Raz; Yael Keren-Zur; Henri Atlan; Irun R Cohen
T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides.
Journal of autoimmunity 1999;12(2):121-9.
1999: M Rechter; Ofer Lider; Liora Cahalon; E Baharav; Mara Dekel; D Seigel; Israel Vlodavsky; Helena Aingorn; Irun R Cohen; Oded Shoseyov
A cellulose-binding domain-fused recombinant human T cell connective tissue-activating peptide-III manifests heparanase activity.
Biochemical and biophysical research communications 1999;255(3):657-62.
1999: A C Figueiredo; Irun R Cohen; Felix Mor
Diversity of the B cell repertoire to myelin basic protein in rat strains susceptible and resistant to EAE.
Journal of autoimmunity 1999;12(1):13-25.
1999: V Ablamunits; D Elias; Irun R Cohen
The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse.
Clinical and experimental immunology 1999;115(2):260-7.
1999: S Könen-Waisman; A Cohen; M Fridkin; Irun R Cohen
Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection.
The Journal of infectious diseases 1999;179(2):403-13.
1999: I Leykin; B Spivak; A Weizman; Irun R Cohen; Meir Shinitzky
Elevated cellular immune response to human heat-shock protein-60 in schizophrenic patients.
European archives of psychiatry and clinical neuroscience 1999;249(5):238-46.
1999: G Moalem; R Leibowitz-Amit; Eti Yoles; Felix Mor; Irun R Cohen; Michal Schwartz
Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy.
Nature medicine 1999;5(1):49-55.
1998: N Erez-Alon; Johannes Herkel; roland wolkowicz; PJ Ruiz; Ari Waisman; Varda Rotter; Irun R Cohen
Immunity to p53 induced by an idiotypic network of anti-p53 antibodies: generation of sequence-specific anti-DNA antibodies and protection from tumor metastasis.
Cancer research 1998;58(23):5447-52.
1998: D L Hirschberg; G Moalem; J He; Felix Mor; Irun R Cohen; Michal Schwartz
Accumulation of passively transferred primed T cells independently of their antigen specificity following central nervous system trauma.
Journal of neuroimmunology 1998;89(1-2):88-96.
1998: Henri Atlan; Irun R Cohen
Immune information, self-organization and meaning.
International immunology 1998;10(6):711-7.
1998: Pedro J Ruiz; roland wolkowicz; Ari Waisman; DL Hirschberg; Pnina Carmi; Neta Erez; Hideki Garren; Johannes Herkel; marcela karpuj; Lawrence Steinman; Varda Rotter; Irun R Cohen
Idiotypic immunization induces immunity to mutated p53 and tumor rejection.
Nature medicine 1998;4(6):710-2.
1998: Boris Reizis; M Eisenstein; Felix Mor; Irun R Cohen
The peptide-binding strategy of the MHC class II I-A molecules.
Immunology today 1998;19(5):212-6.
1998: V Ablamunits; D Elias; Tamar Reshef; Irun R Cohen
Islet T cells secreting IFN-gamma in NOD mouse diabetes: arrest by p277 peptide treatment.
Journal of autoimmunity 1998;11(1):73-81.
1997: Boris Reizis; D M Altmann; Irun R Cohen
Biochemical characterization of the human diabetes-associated HLA-DQ8 allelic product: similarity to the major histocompatibility complex class II I-A(g)7 protein of non-obese diabetic mice.
European journal of immunology 1997;27(10):2478-83.
1997: Liora Cahalon; Ofer Lider; H Schor; A Avron; D Gilat; Rami Hershkoviz; Raanan Margalit; A Eshel; O Shoseyev; Irun R Cohen
Heparin disaccharides inhibit tumor necrosis factor-alpha production by macrophages and arrest immune inflammation in rodents.
International immunology 1997;9(10):1517-22.
1997: J Bockova; D Elias; Irun R Cohen
Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies.
Journal of autoimmunity 1997;10(4):323-9.
1997: Irun R Cohen
Questions about NOD mouse diabetes.
Research in immunology 1997;148(5):286-91.
1997: D Elias; A Meilin; V Ablamunits; Ohad Birk; Pnina Carmi; S Könen-Waisman; Irun R Cohen
Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens.
Diabetes 1997;46(5):758-64.
1997: Boris Reizis; M Eisenstein; J Bocková; S Könen-Waisman; Felix Mor; D Elias; Irun R Cohen
Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7.
International immunology 1997;9(1):43-51.
1997: Boris Reizis; H Schild; S Stefanović; Felix Mor; H Rammensee; Irun R Cohen
Peptide binding motifs of the MHC class I molecules (RT1.Al) of the Lewis rat.
Immunogenetics 1997;45(4):278-9.
1996: Boris Reizis; Felix Mor; Miriam Eisenstein; H Schild; S Stefanoviç; H G Rammensee; Irun R Cohen
The peptide binding specificity of the MHC class II I-A molecule of the Lewis rat, RT1.BI.
International immunology 1996;8(12):1825-32.
1996: Felix Mor; Boris Reizis; Irun R Cohen; Lawrence Steinman
IL-2 and TNF receptors as targets of regulatory T-T interactions: isolation and characterization of cytokine receptor-reactive T cell lines in the Lewis rat.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4855-61.
1996: Felix Mor; M Kantorowitz; Irun R Cohen
The dominant and the cryptic T cell repertoire to myelin basic protein in the Lewis rat.
Journal of neuroscience research 1996;45(6):670-9.
1996: D Elias; Irun R Cohen
The hsp60 peptide p277 arrests the autoimmune diabetes induced by the toxin streptozotocin.
Diabetes 1996;45(9):1168-72.
1996: Ari Waisman; Pedro J Ruiz; DL Hirschberg; A Gelman; Jorge R Oksenberg; S Brocke; Felix Mor; Irun R Cohen; Lawrence Steinman
Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity.
Nature medicine 1996;2(8):899-905.
1996: Arie Ben-Yehuda; R Bar-Tana; A Livoff; N Ron; Irun R Cohen; Yaakov Naparstek
Lymph node cell vaccination against the lupus syndrome of MRL/lpr/lpr mice.
Lupus 1996;5(3):232-6.
1996: Ohad Birk; D Elias; A S Weiss; A Rosen; R van-der Zee; Michael D Walker; Irun R Cohen
NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells.
Journal of autoimmunity 1996;9(2):159-66.
1996: Ohad Birk; D C Douek; D Elias; K Takacs; H Dewchand; S L Gur; Michael D Walker; R van der Zee; Irun R Cohen; Daniel M Altmann
A role of Hsp60 in autoimmune diabetes: analysis in a transgenic model.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1032-7.
1996: Felix Mor; Irun R Cohen
IL-2 rescues antigen-specific T cells from radiation or dexamethasone-induced apoptosis. Correlation with induction of Bcl-2.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):515-22.
1996: Irun R Cohen
Kadishman's tree, Escher's angels, and the immunological homunculus.
Israel journal of medical sciences 1996;32(1):44-50.
1995: D Elias; Hadar Marcus; Tamar Reshef; V Ablamunits; Irun R Cohen
Induction of diabetes in standard mice by immunization with the p277 peptide of a 60-kDa heat shock protein.
European journal of immunology 1995;25(10):2851-7.
1995: Felix Mor; Irun R Cohen
Pathogenicity of T cells responsive to diverse cryptic epitopes of myelin basic protein in the Lewis rat.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3693-9.
1995: D Elias; Irun R Cohen
Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277.
Diabetes 1995;44(9):1132-8.
1995: Boris Reizis; Felix Mor; Irun R Cohen
Functional activation of encephalitogenic T cells in the absence of antigen-presenting cells.
International immunology 1995;7(8):1375-9.
1995: S Könen-Waisman; Mati Fridkin; Irun R Cohen
Self and foreign 60-kilodalton heat shock protein T cell epitope peptides serve as immunogenic carriers for a T cell-independent sugar antigen.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5977-85.
1995: Ofer Lider; Liora Cahalon; D Gilat; Rami Hershkoviz; D Siegel; Raanan Margalit; Oded Shoseyov; Irun R Cohen
A disaccharide that inhibits tumor necrosis factor alpha is formed from the extracellular matrix by the enzyme heparanase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5037-41.
1995: L A Segel; E Jäger; D Elias; Irun R Cohen
A quantitative model of autoimmune disease and T-cell vaccination: does more mean less?
Immunology today 1995;16(2):80-4.
1995: Irun R Cohen
Language, meaning and the immune system.
Israel journal of medical sciences 1995;31(1):36-7.
1994: Boris Reizis; C Schramm; Irun R Cohen; Felix Mor
Expression of major histocompatibility complex class II molecules in rat T cells.
European journal of immunology 1994;24(11):2796-802.
1994: D Elias; H Prigozin; N Polak; M Rapoport; A W Lohse; Irun R Cohen
Autoimmune diabetes induced by the beta-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin.
Diabetes 1994;43(8):992-8.
1994: C Verhagen; Felix Mor; Irun R Cohen
T cell immunity to myelin basic protein induces anterior uveitis in Lewis rats.
Journal of neuroimmunology 1994;53(1):65-71.
1994: D Elias; Irun R Cohen
Peptide therapy for diabetes in NOD mice.
Lancet 1994;343(8899):704-6.
1994: Irun R Cohen
Autoimmunity shifts paradigms.
Israel journal of medical sciences 1994;30(3):37-8.
1994: A Achiron; Raanan Margalit; Rami Hershkoviz; D Markovits; Tamar Reshef; E Melamed; Irun R Cohen; Ofer Lider
Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor alpha secretion.
The Journal of clinical investigation 1994;93(2):600-5.
1994: L Levy; C D Enk; D Zipris; Irun R Cohen
Protection of mice against mycobacterial infection by lymphoid cell vaccination.
Israel journal of medical sciences 1994;30(1):22-5.
1993: Ohad Birk; Irun R Cohen
T-cell autoimmunity in type 1 diabetes mellitus.
Current opinion in immunology 1993;5(6):903-9.
1993: Felix Mor; Irun R Cohen
Shifts in the epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 1993;92(5):2199-206.
1993: Felix Mor; Irun R Cohen
T cell vaccines for autoimmune diseases.
Annals of the New York Academy of Sciences 1993;685():784-7.
1993: O M Shapira; E Mor; Tamar Reshef; R A Pfeffermann; Irun R Cohen
Prolongation of survival of rat cardiac allografts by T cell vaccination.
The Journal of clinical investigation 1993;91(2):388-90.
1993: Irun R Cohen
The meaning of the immunological homunculus.
Israel journal of medical sciences 1993;29(2-3):173-4.
1993: Rami Hershkoviz; D Gilat; Shmuel Miron; Yoseph A Mekori; D Aderka; David Wallach; Israel Vlodavsky; Irun R Cohen; Ofer Lider
Extracellular matrix induces tumour necrosis factor-alpha secretion by an interaction between resting rat CD4+ T cells and macrophages.
Immunology 1993;78(1):50-7.
1993: Irun R Cohen; Felix Mor
On the regulation of EAE.
International reviews of immunology 1993;9(4):243-9.
1992: Irun R Cohen
The cognitive paradigm and the immunological homunculus.
Immunology today 1992;13(12):490-4.
1992: Felix Mor; Irun R Cohen
T cells in the lesion of experimental autoimmune encephalomyelitis. Enrichment for reactivities to myelin basic protein and to heat shock proteins.
The Journal of clinical investigation 1992;90(6):2447-55.
1992: Irun R Cohen
The cognitive principle challenges clonal selection.
Immunology today 1992;13(11):441-4.
1992: R Zerubavel-Weiss; D Markovits; Irun R Cohen
Autoimmune thyroiditis (EAT) in genetically resistant mice mediated by a T cell line.
Journal of autoimmunity 1992;5(5):617-27.
1992: Maria Giovanna Danieli; D Markovits; Armando Gabrielli; A Corvetta; P L Giorgi; R van der Zee; J D van Embden; Giovanni Danieli; Irun R Cohen
Juvenile rheumatoid arthritis patients manifest immune reactivity to the mycobacterial 65-kDa heat shock protein, to its 180-188 peptide, and to a partially homologous peptide of the proteoglycan link protein.
Clinical immunology and immunopathology 1992;64(2):121-8.
1992: Maria Giovanna Danieli; M Candela; A M Ricciatti; R Reginelli; Giovanni Danieli; Irun R Cohen; Armando Gabrielli
Antibodies to mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma).
Journal of autoimmunity 1992;5(4):443-52.
1992: Irun R Cohen
Immunologically specific treatment of spontaneous insulin-dependent diabetes mellitus of NOD mice.
Journal of autoimmunity 1992;5 Suppl A():227-30.
1992: Rami Hershkoviz; Felix Mor; D Gilat; Irun R Cohen; Ofer Lider
T cells in the spinal cord in experimental autoimmune encephalomyelitis are matrix adherent and secrete tumor necrosis factor alpha.
Journal of neuroimmunology 1992;37(1-2):161-6.
1992: Felix Mor; Irun R Cohen
Analysis of the autoimmune infiltrate in experimental encephalomyelitis.
Israel journal of medical sciences 1992;28(2):139-40.
1992: Rami Hershkoviz; Shmuel Miron; Irun R Cohen; A Miller; Ofer Lider
T lymphocyte adhesion to the fibronectin and laminin components of the extracellular matrix is regulated by the CD4 molecule.
European journal of immunology 1992;22(1):7-13.
1992: Irun R Cohen
Autoimmunity to hsp65 and the immunologic paradigm.
Advances in internal medicine 1992;37():295-311.
1992: Israel Vlodavsky; Amiram Eldor; Adriana Haimovitz-Friedman; Yaacov Matzner; Rivka Ishai-Michaeli; O Lider; Yaakov Naparstek; Irun R Cohen; Z Fuks
Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation.
Invasion & metastasis 1992;12(2):112-27.
1991: D Elias; Tamar Reshef; Ohad Birk; R van der Zee; Michael D Walker; Irun R Cohen
Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3088-91.
1991: Irun R Cohen; D B Young
Autoimmunity, microbial immunity and the immunological homunculus.
Immunology today 1991;12(4):105-10.
1991: Irun R Cohen
Autoimmunity to chaperonins in the pathogenesis of arthritis and diabetes.
Annual review of immunology 1991;9():567-89.
1990: Irun R Cohen
A heat shock protein, molecular mimicry and autoimmunity.
Israel journal of medical sciences 1990;26(12):673-6.
1990: D Elias; A J Bone; J D Baird; A Cooke; Irun R Cohen
Insulin-mimicking anti-idiotypic antibodies in development of spontaneous autoimmune diabetes in BB/E rats.
Diabetes 1990;39(12):1467-71.
1990: Yaakov Naparstek; A Ben-Yehuda; Irun R Cohen; R Bar-Tana
Crossreactivity of anti-DNA antibodies.
Immunology today 1990;11(11):388-9.
1990: Yaakov Naparstek; Arie Ben-Yehuda; Michael P. Madaio; R Bar-Tana; Lucia Schuger; Galina Pizov; Ziv Neeman; Irun R Cohen
Binding of anti-DNA antibodies and inhibition of glomerulonephritis in MRL-lpr/lpr mice by heparin.
Arthritis and rheumatism 1990;33(10):1554-9.
1990: Felix Mor; A W Lohse; N Karin; Irun R Cohen
Clinical modeling of T cell vaccination against autoimmune diseases in rats. Selection of antigen-specific T cells using a mitogen.
The Journal of clinical investigation 1990;85(5):1594-8.
1990: Ofer Lider; Yoseph A Mekori; T Miller; R Bar-Tana; Israel Vlodavsky; E Baharav; Irun R Cohen; Yaakov Naparstek
Inhibition of T lymphocyte heparanase by heparin prevents T cell migration and T cell-mediated immunity.
European journal of immunology 1990;20(3):493-9.
1990: D Elias; D Markovits; Tamar Reshef; R van der Zee; Irun R Cohen
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1576-80.
1989: Irun R Cohen
Autoimmunity to receptors.
Israel journal of medical sciences 1989;25(12):695-7.
1989: Irun R Cohen; H Atlan
Network regulation of autoimmunity: an automation model.
Journal of autoimmunity 1989;2(5):613-25.
1989: A Friedman; Ofer Lider; E Beraud; Irun R Cohen
Absence of major histocompatibility complex restriction in the interaction between processed basic protein and Ia of two rat strains.
Scandinavian journal of immunology 1989;29(6):747-50.
1989: A W Lohse; Felix Mor; N Karin; Irun R Cohen
Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells.
Science (New York, N.Y.) 1989;244(4906):820-2.
1989: Irun R Cohen
Insulin-dependent diabetes mellitus.
Current opinion in immunology 1989;1(4):727-32.
1989: Ofer Lider; E Baharav; Yoseph A Mekori; T Miller; Yaakov Naparstek; Israel Vlodavsky; Irun R Cohen
Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins.
The Journal of clinical investigation 1989;83(3):752-6.
1989: Irun R Cohen
T-cell vaccination against autoimmune disease.
Hospital practice (Office ed.) 1989;24(2):57-64.
1989: Ofer Lider; E Beraud; Tamar Reshef; A Friedman; Irun R Cohen
Vaccination against experimental autoimmune encephalomyelitis using a subencephalitogenic dose of autoimmune effector T cells. (2). Induction of a protective anti-idiotypic response.
Journal of autoimmunity 1989;2(1):87-99.
1989: E Beraud; Ofer Lider; E Baharav; Tamar Reshef; Irun R Cohen
Vaccination against experimental autoimmune encephalomyelitis using a subencephalitogenic dose of autoimmune effector cells (1). Characteristics of vaccination.
Journal of autoimmunity 1989;2(1):75-86.
1989: Irun R Cohen
Physiological basis of T-cell vaccination against autoimmune disease.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():879-84.
1988: Irun R Cohen
Vaccination against experimental autoimmune disease using autoimmune T-lymphocytes.
Israel journal of medical sciences 1988;24(12):734-6.
1988: D Elias; M Rapoport; Irun R Cohen; Yoram Shechter
Desensitization of the insulin receptor by antireceptor antibodies in vivo is blocked by treatment of mice with beta-adrenergic agonists.
The Journal of clinical investigation 1988;81(6):1979-85.
1988: Ofer Lider; Tamar Reshef; E Beraud; Avraham Ben-Nun; Irun R Cohen
Anti-idiotypic network induced by T cell vaccination against experimental autoimmune encephalomyelitis.
Science (New York, N.Y.) 1988;239(4836):181-3.
1987: Daniel M Altmann; Ofer Lider; D C Douek; Irun R Cohen
Activation of specific T cell lines by the antigens avidin and myelin basic protein in the absence of antigen-presenting cells.
European journal of immunology 1987;17(11):1635-40.
1986: E Beraud; Tamar Reshef; Arthur Vandenbark; Halina Offner; R Friz; C H Chou; D Bernard; Irun R Cohen
Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: genotype of antigen-presenting cells influences immunodominant epitope of basic protein.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(2):511-5.