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Jeffrey Cohen
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21
Pesnicak, Lesley
15
Straus, Stephen
7
Krogmann, Tammy
6
Ali, Mir
6
Purcell, Robert
6
Sato, Hitoshi
5
Prikhod'ko, Elena
5
hoshino, yo
4
Ticehurst, John
4
Wang, GH
4
Bertin, John
4
Feinstone, Stephen
4
Hohman, Patricia
3
Dowdell, Kennichi
3
Moriuchi, H
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All Publications
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2009: Hoshino Yo; Katano Harutaka; Zou Ping; Hohman Patricia; Marques Adriana; Tyring Stephen K; Follmann Dean; Cohen Jeffrey I
Long-term administration of valacyclovir reduces the number of Epstein-Barr virus (EBV)-infected B cells but not the number of EBV DNA copies per B cell in healthy volunteers.
Journal of virology 2009;83(22):11857-61.
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2009: Hoshino Yo; Pesnicak Lesley; Dowdell Kennichi C; Burbelo Peter D; Knipe David M; Straus Stephen E; Cohen Jeffrey I
Protection from herpes simplex virus (HSV)-2 infection with replication-defective HSV-2 or glycoprotein D2 vaccines in HSV-1-seropositive and HSV-1-seronegative guinea pigs.
The Journal of infectious diseases 2009;200(7):1088-95.
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2009: Sashihara Junji; Burbelo Peter D; Savoldo Barbara; Pierson Theodore C; Cohen Jeffrey I
Human antibody titers to Epstein-Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay.
Virology 2009;391(2):249-56.
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2009: Cohen J I; Kimura H; Nakamura S; Ko Y-H; Jaffe E S
Epstein-Barr virus-associated lymphoproliferative disease in non-immunocompromised hosts: a status report and summary of an international meeting, 8-9 September 2008.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(9):1472-82.
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2009: Cohen Jeffrey I
Cytomegalovirus in the intensive care unit: pathogen or passenger?
Critical care medicine 2009;37(6):2095-6.
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2009: Kawada Junichi; Zou Ping; Mazitschek Ralph; Bradner James E; Cohen Jeffrey I
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
The Journal of biological chemistry 2009;284(25):17102-9.
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2009: Cohen Jeffrey I
Optimal treatment for chronic active Epstein-Barr virus disease.
Pediatric transplantation 2009;13(4):393-6.
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2009: Hoshino Yo; Pesnicak Lesley; Straus Stephen E; Cohen Jeffrey I
Impairment in reactivation of a latency associated transcript (LAT)-deficient HSV-2 is not solely dependent on the latent viral load or the number of CD8(+) T cells infiltrating the ganglia.
Virology 2009;387(1):193-9.
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2009: Ali Mir A; Li Qingxue; Fischer Elizabeth R; Cohen Jeffrey I
The insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection.
Virology 2009;386(2):270-9.
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2009: Dowdell Kennichi C; Pesnicak Lesley; Hoffmann Victoria; Steadman Kenneth; Remaley Alan T; Cohen Jeffrey I; Straus Stephen E; Rao V Koneti
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS).
Experimental hematology 2009;37(4):487-94.
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2009: Wang Kening; Mahalingam Gowtham; Imai Yumi; Pesnicak Lesley; Margolis Todd P; Straus Stephen E; Cohen Jeffrey I
Cell type specific accumulation of the major latency-associated transcript (LAT) of herpes simplex virus type 2 in LAT transgenic mice.
Virology 2009;386(1):79-87.
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2009: Ambagala Aruna P; Bosma Trent; Ali Mir A; Poustovoitov Maxim; Chen Jason J; Gershon Michael D; Adams Peter D; Cohen Jeffrey I
Varicella-zoster virus immediate-early 63 protein interacts with human antisilencing function 1 protein and alters its ability to bind histones h3.1 and h3.3.
Journal of virology 2009;83(1):200-9.
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2008: Hoshino Yo; Pesnicak Lesley; Dowdell Kennichi C; Lacayo Juan; Dudek Timothy; Knipe David M; Straus Stephen E; Cohen Jeffrey I
Comparison of immunogenicity and protective efficacy of genital herpes vaccine candidates herpes simplex virus 2 dl5-29 and dl5-29-41L in mice and guinea pigs.
Vaccine 2008;26(32):4034-40.
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2008: Cohen Jeffrey I
Strategies for herpes zoster vaccination of immunocompromised patients.
The Journal of infectious diseases 2008;197 Suppl 2():S237-41.
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2008: Hoshino Yo; Qin Jing; Follmann Dean; Cohen Jeffrey I; Straus Stephen E
The number of herpes simplex virus-infected neurons and the number of viral genome copies per neuron correlate with the latent viral load in ganglia.
Virology 2008;372(1):56-63.
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2008: Cohen Jeffrey I; Bollard Catherine M; Khanna Rajiv; Pittaluga Stefania
Current understanding of the role of Epstein-Barr virus in lymphomagenesis and therapeutic approaches to EBV-associated lymphomas.
Leukemia & lymphoma 2008;49 Suppl 1():27-34.
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2007: Zou Ping; Kawada Junichi; Pesnicak Lesley; Cohen Jeffrey I
Bortezomib induces apoptosis of Epstein-Barr virus (EBV)-transformed B cells and prolongs survival of mice inoculated with EBV-transformed B cells.
Journal of virology 2007;81(18):10029-36.
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2007: Li Qingxue; Krogmann Tammy; Ali Mir A; Tang Wei-Jen; Cohen Jeffrey I
The amino terminus of varicella-zoster virus (VZV) glycoprotein E is required for binding to insulin-degrading enzyme, a VZV receptor.
Journal of virology 2007;81(16):8525-32.
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2007: Hoshino Yo; Pesnicak Lesley; Cohen Jeffrey I; Straus Stephen E
Rates of reactivation of latent herpes simplex virus from mouse trigeminal ganglia ex vivo correlate directly with viral load and inversely with number of infiltrating CD8+ T cells.
Journal of virology 2007;81(15):8157-64.
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2007: Ambagala Aruna P N; Cohen Jeffrey I
Varicella-Zoster virus IE63, a major viral latency protein, is required to inhibit the alpha interferon-induced antiviral response.
Journal of virology 2007;81(15):7844-51.
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2007: Wang Kening; Mahalingam Gowtham; Hoover Susan E; Mont Erik K; Holland Steven M; Cohen Jeffrey I; Straus Stephen E
Diverse herpes simplex virus type 1 thymidine kinase mutants in individual human neurons and Ganglia.
Journal of virology 2007;81(13):6817-26.
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2007: Cohen Jeffrey I; Hohman Patricia; Preuss Jeanne C; Li Li; Fischer Steven H; Fedorko Daniel P
Detection of vaccinia virus DNA, but not infectious virus, in the blood of smallpox vaccine recipients.
Vaccine 2007;25(23):4571-4.
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2007: Cohen Jeffrey I; Krogmann Tammy; Pesnicak Lesley; Ali Mir A
Absence or overexpression of the Varicella-Zoster Virus (VZV) ORF29 latency-associated protein impairs late gene expression and reduces VZV latency in a rodent model.
Journal of virology 2007;81(4):1586-91.
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2007: Cohen Jeffrey I
Varicella-zoster vaccine virus: evolution in action.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(1):7-8.
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2006: Li Qingxue; Ali Mir A; Cohen Jeffrey I
Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread.
Cell 2006;127(2):305-16.
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2006: Hoover Susan E; Cohrs Randall J; Rangel Zoila G; Gilden Donald H; Munson Peter; Cohen Jeffrey I
Downregulation of varicella-zoster virus (VZV) immediate-early ORF62 transcription by VZV ORF63 correlates with virus replication in vitro and with latency.
Journal of virology 2006;80(7):3459-68.
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2005: Fedorko Daniel P; Preuss Jeanne C; Fahle Gary A; Li Li; Fischer Steven H; Hohman Patricia; Cohen Jeffrey I
Comparison of methods for detection of vaccinia virus in patient specimens.
Journal of clinical microbiology 2005;43(9):4602-6.
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2005: Hu Huiling; Cohen Jeffrey I
Varicella-zoster virus open reading frame 47 (ORF47) protein is critical for virus replication in dendritic cells and for spread to other cells.
Virology 2005;337(2):304-11.
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2005: Cohen Jeffrey I; Krogmann Tammy; Ross Jeffrey P; Pesnicak Lesley; Prikhod'ko Elena A
Varicella-zoster virus ORF4 latency-associated protein is important for establishment of latency.
Journal of virology 2005;79(11):6969-75.
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2005: Cohen J I
HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.
British journal of cancer 2005;92(9):1593-8.
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2005: Cohen Jeffrey I; Krogmann Tammy; Bontems Sebastien; Sadzot-Delvaux Catherine; Pesnicak Lesley
Regions of the varicella-zoster virus open reading frame 63 latency-associated protein important for replication in vitro are also critical for efficient establishment of latency.
Journal of virology 2005;79(8):5069-77.
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2005: Cohen Jeffrey I
Licking latency with licorice.
The Journal of clinical investigation 2005;115(3):591-3.
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2005: Hoshino Yo; Dalai Sarat K; Wang Kening; Pesnicak Lesley; Lau Tsz Y; Knipe David M; Cohen Jeffrey I; Straus Stephen E
Comparative efficacy and immunogenicity of replication-defective, recombinant glycoprotein, and DNA vaccines for herpes simplex virus 2 infections in mice and guinea pigs.
Journal of virology 2005;79(1):410-8.
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2004: Cohen Jeffrey I; Cox Edward; Pesnicak Lesley; Srinivas Shamala; Krogmann Tammy
The varicella-zoster virus open reading frame 63 latency-associated protein is critical for establishment of latency.
Journal of virology 2004;78(21):11833-40.
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2004: Prikhod'ko Elena A; Prikhod'ko Grigori G; Siegel Richard M; Thompson Peter; Major Marian E; Cohen Jeffrey I
The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities.
Virology 2004;329(1):53-67.
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2004: Heineman Thomas C; Pesnicak Lesley; Ali Mir A; Krogmann Tammy; Krudwig Nancy; Cohen Jeffrey I
Varicella-zoster virus expressing HSV-2 glycoproteins B and D induces protection against HSV-2 challenge.
Vaccine 2004;22(20):2558-65.
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2004: Katano Harutaka; Pesnicak Lesley; Cohen Jeffrey I
Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4960-5.
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2004: Katano Harutaka; Ali Mir A; Patera Andriani C; Catalfamo Marta; Jaffe Elaine S; Kimura Hiroshi; Dale Janet K; Straus Stephen E; Cohen Jeffrey I
Chronic active Epstein-Barr virus infection associated with mutations in perforin that impair its maturation.
Blood 2004;103(4):1244-52.
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2003: Sato Hitoshi; Pesnicak Lesley; Cohen Jeffrey I
Varicella-zoster virus ORF47 protein kinase, which is required for replication in human T cells, and ORF66 protein kinase, which is expressed during latency, are dispensable for establishment of latency.
Journal of virology 2003;77(20):11180-5.
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2003: Sosnovtsev Stanislav V; Prikhod'ko Elena A; Belliot Gaël; Cohen Jeffrey I; Green Kim Y
Feline calicivirus replication induces apoptosis in cultured cells.
Virus research 2003;94(1):1-10.
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2003: Cohen Jeffrey I
Benign and malignant Epstein-Barr virus-associated B-cell lymphoproliferative diseases.
Seminars in hematology 2003;40(2):116-23.
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2003: Xia Dongxiang; Srinivas Shamala; Sato Hitoshi; Pesnicak Lesley; Straus Stephen E; Cohen Jeffrey I
Varicella-zoster virus open reading frame 21, which is expressed during latency, is essential for virus replication but dispensable for establishment of latency.
Journal of virology 2003;77(2):1211-8.
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2003: Sato Hitoshi; Pesnicak Lesley; Cohen Jeffrey I
Use of a rodent model to show that varicella-zoster virus ORF61 is dispensable for establishment of latency.
Journal of medical virology 2003;70 Suppl 1():S79-81.
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2002: Cohen Jeffrey I; Davenport David S; Stewart John A; Deitchman Scott; Hilliard Julia K; Chapman Louisa E;
Recommendations for prevention of and therapy for exposure to B virus (cercopithecine herpesvirus 1).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;35(10):1191-203.
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2002: Sato Hitoshi; Callanan Lawrence D; Pesnicak Lesley; Krogmann Tammy; Cohen Jeffrey I
Varicella-zoster virus (VZV) ORF17 protein induces RNA cleavage and is critical for replication of VZV at 37 degrees C but not 33 degrees C.
Journal of virology 2002;76(21):11012-23.
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2002: Patera Andriani; Ali Mir A; Tyring Stephen; Warren Terri; Hohman Patricia; Yu Evangeline; Cohen Jeffrey I
Polymorphisms in the genes for herpesvirus entry.
The Journal of infectious diseases 2002;186(3):444-5.
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2002: Patera Andriani C; Pesnicak Lesley; Bertin John; Cohen Jeffrey I
Interleukin 17 modulates the immune response to vaccinia virus infection.
Virology 2002;299(1):56-63.
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2002: Prikhod'ko Grigori G; Prikhod'ko Elena A; Pletnev Alexander G; Cohen Jeffrey I
Langat flavivirus protease NS3 binds caspase-8 and induces apoptosis.
Journal of virology 2002;76(11):5701-10.
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2002: Sato Hitoshi; Pesnicak Lesley; Cohen Jeffrey I
Varicella-zoster virus open reading frame 2 encodes a membrane phosphoprotein that is dispensable for viral replication and for establishment of latency.
Journal of virology 2002;76(7):3575-8.
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2002: Garvey Tara L; Bertin John; Siegel Richard M; Wang G H; Lenardo Michael J; Cohen Jeffrey I
Binding of FADD and caspase-8 to molluscum contagiosum virus MC159 v-FLIP is not sufficient for its antiapoptotic function.
Journal of virology 2002;76(2):697-706.
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2001: Prikhod'ko G G; Prikhod'ko E A; Cohen J I; Pletnev A G
Infection with Langat Flavivirus or expression of the envelope protein induces apoptotic cell death.
Virology 2001;286(2):328-35.
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2001: Cohen J I; Sato H; Srinivas S; Lekstrom K
Varicella-zoster virus (VZV) ORF65 virion protein is dispensable for replication in cell culture and is phosphorylated by casein kinase II, but not by the VZV protein kinases.
Virology 2001;280(1):62-71.
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2001: Cohen J I
Mutagenesis of the varicella-zoster virus genome: lessons learned.
Archives of virology. Supplementum 2001;(17):91-7.
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2000: Cohen J I
Epstein-Barr virus infection.
The New England journal of medicine 2000;343(7):481-92.
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2000: Soong W; Schultz J C; Patera A C; Sommer M H; Cohen J I
Infection of human T lymphocytes with varicella-zoster virus: an analysis with viral mutants and clinical isolates.
Journal of virology 2000;74(4):1864-70.
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1999: Wang G H; Garvey T L; Cohen J I
The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis.
The Journal of general virology 1999;80 ( Pt 10)():2737-40.
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1999: Cohen J I; Lekstrom K
Epstein-Barr virus BARF1 protein is dispensable for B-cell transformation and inhibits alpha interferon secretion from mononuclear cells.
Journal of virology 1999;73(9):7627-32.
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1999: Cohen J I
The biology of Epstein-Barr virus: lessons learned from the virus and the host.
Current opinion in immunology 1999;11(4):365-70.
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1999: Cohen J I; Brunell P A; Straus S E; Krause P R
Recent advances in varicella-zoster virus infection.
Annals of internal medicine 1999;130(11):922-32.
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1998: Reddy S M; Williams M; Cohen J I
Expression of a uracil DNA glycosylase (UNG) inhibitor in mammalian cells: varicella-zoster virus can replicate in vitro in the absence of detectable UNG activity.
Virology 1998;251(2):393-401.
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1998: Cox E; Reddy S; Iofin I; Cohen J I
Varicella-zoster virus ORF57, unlike its pseudorabies virus UL3.5 homolog, is dispensable for viral replication in cell culture.
Virology 1998;250(1):205-9.
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1998: Reddy S M; Cox E; Iofin I; Soong W; Cohen J I
Varicella-zoster virus (VZV) ORF32 encodes a phosphoprotein that is posttranslationally modified by the VZV ORF47 protein kinase.
Journal of virology 1998;72(10):8083-8.
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1998: Moffat J F; Zerboni L; Sommer M H; Heineman T C; Cohen J I; Kaneshima H; Arvin A M
The ORF47 and ORF66 putative protein kinases of varicella-zoster virus determine tropism for human T cells and skin in the SCID-hu mouse.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11969-74.
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1998: Kimura H; Wang Y; Pesnicak L; Cohen J I; Hooks J J; Straus S E; Williams R K
Recombinant varicella-zoster virus glycoproteins E and I: immunologic responses and clearance of virus in a guinea pig model of chronic uveitis.
The Journal of infectious diseases 1998;178(2):310-7.
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1998: Cohen J I
Infection of cells with varicella-zoster virus down-regulates surface expression of class I major histocompatibility complex antigens.
The Journal of infectious diseases 1998;177(5):1390-3.
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1998: Cohen J I; Wang Y; Nussenblatt R; Straus S E; Hooks J J
Chronic uveitis in guinea pigs infected with varicella-zoster virus expressing Escherichia coli beta-galactosidase.
The Journal of infectious diseases 1998;177(2):293-300.
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1997: Wang G H; Bertin J; Wang Y; Martin D A; Wang J; Tomaselli K J; Armstrong R C; Cohen J I
Bovine herpesvirus 4 BORFE2 protein inhibits Fas- and tumor necrosis factor receptor 1-induced apoptosis and contains death effector domains shared with other gamma-2 herpesviruses.
Journal of virology 1997;71(11):8928-32.
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1997: Ross J; Williams M; Cohen J I
Disruption of the varicella-zoster virus dUTPase and the adjacent ORF9A gene results in impaired growth and reduced syncytia formation in vitro.
Virology 1997;234(2):186-95.
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1997: Cohen J I
Epstein-Barr virus and the immune system. Hide and seek.
JAMA : the journal of the American Medical Association 1997;278(6):510-3.
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1997: Bertin J; Armstrong R C; Ottilie S; Martin D A; Wang Y; Banks S; Wang G H; Senkevich T G; Alnemri E S; Moss B; Lenardo M J; Tomaselli K J; Cohen J I
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1172-6.
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1996: Heineman T C; Seidel K; Cohen J I
The varicella-zoster virus ORF66 protein induces kinase activity and is dispensable for viral replication.
Journal of virology 1996;70(10):7312-7.
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1996: Cohen J I
Varicella-zoster virus. The virus.
Infectious disease clinics of North America 1996;10(3):457-68.
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1995: Heineman T C; Cohen J I
The varicella-zoster virus (VZV) open reading frame 47 (ORF47) protein kinase is dispensable for viral replication and is not required for phosphorylation of ORF63 protein, the VZV homolog of herpes simplex virus ICP22.
Journal of virology 1995;69(11):7367-70.
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1995: Moriuchi H; Moriuchi M; Cohen J I
Proteins and cis-acting elements associated with transactivation of the varicella-zoster virus (VZV) immediate-early gene 62 promoter by VZV open reading frame 10 protein.
Journal of virology 1995;69(8):4693-701.
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1995: Moriuchi M; Moriuchi H; Debrus S; Piette J; Cohen J I
The acidic amino-terminal region of varicella-zoster virus open reading frame 4 protein is required for transactivation and can functionally replace the corresponding region of herpes simplex virus ICP27.
Virology 1995;208(1):376-82.
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1994: Cohen J I; Seidel K E
Absence of varicella-zoster virus (VZV) glycoprotein V does not alter growth of VZV in vitro or sensitivity to heparin.
The Journal of general virology 1994;75 ( Pt 11)():3087-93.
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1994: Moriuchi M; Moriuchi H; Straus S E; Cohen J I
Varicella-zoster virus (VZV) virion-associated transactivator open reading frame 62 protein enhances the infectivity of VZV DNA.
Virology 1994;200(1):297-300.
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1993: Cohen J I; Seidel K E
Generation of varicella-zoster virus (VZV) and viral mutants from cosmid DNAs: VZV thymidylate synthetase is not essential for replication in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7376-80.
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1992: Cohen J I
A region of herpes simplex virus VP16 can substitute for a transforming domain of Epstein-Barr virus nuclear protein 2.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8030-4.
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1991: Cohen J I; Kieff E
An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator.
Journal of virology 1991;65(11):5880-5.
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1989: Cohen J I; Rosenblum B; Feinstone S M; Ticehurst J; Purcell R H
Attenuation and cell culture adaptation of hepatitis A virus (HAV): a genetic analysis with HAV cDNA.
Journal of virology 1989;63(12):5364-70.
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1989: Cohen J I; Feinstone S; Purcell R H
Hepatitis A virus infection in a chimpanzee: duration of viremia and detection of virus in saliva and throat swabs.
The Journal of infectious diseases 1989;160(5):887-90.
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1989: Cohen J I
Hepatitis A virus: insights from molecular biology.
Hepatology (Baltimore, Md.) 1989;9(6):889-95.
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1988: Cohen J I; Miller R H; Rosenblum B; Denniston K; Gerin J L; Purcell R H
Sequence comparison of woodchuck hepatitis virus replicative forms shows conservation of the genome.
Virology 1988;162(1):12-20.
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1987: Cohen J I; Ticehurst J R; Feinstone S M; Rosenblum B; Purcell R H
Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture.
Journal of virology 1987;61(10):3035-9.
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1987: Cohen J I; Rosenblum B; Ticehurst J R; Daemer R J; Feinstone S M; Purcell R H
Complete nucleotide sequence of an attenuated hepatitis A virus: comparison with wild-type virus.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2497-501.
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1987: Cohen J I; Ticehurst J R; Purcell R H; Buckler-White A; Baroudy B M
Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses.
Journal of virology 1987;61(1):50-9.
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