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Philip Cohen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Lymphocyte Activation

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Co-Publications
Name
59
Eisenberg, Robert
16
Reap, Elizabeth
15
Sobel, Eric
10
Kakkanaiah, VN
9
Caricchio, Roberto
5
Maldonado, Michael
4
Clarke, Stephen
3
Chen, Fangqi
3
Choudhury, Arpita
3
Fecho, Karamarie
3
MacDonald, GC
3
Weintraub, JP
3
Madaio, Michael P.
2
St Clair, William
2
Treadwell, Edward

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Publications

TOP 3
Shao Wen-Hai; Zhen Yuxuan; Eisenberg Robert A; Cohen Philip L
The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells.
Yunk Lenka; Meng Wenzhao; Cohen Philip L; Eisenberg Robert A; Luning Prak Eline T
Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement.
Tsao Patricia Y; Jiao Jing; Ji Mei Qing; Cohen Philip L; Eisenberg Robert A
T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice.

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All Publications

2009: Shao Wen-Hai; Zhen Yuxuan; Eisenberg Robert A; Cohen Philip L
The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells.
Clinical immunology (Orlando, Fla.) 2009;133(1):138-44.
2009: Yunk Lenka; Meng Wenzhao; Cohen Philip L; Eisenberg Robert A; Luning Prak Eline T
Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):452-61.
2008: Tsao Patricia Y; Jiao Jing; Ji Mei Qing; Cohen Philip L; Eisenberg Robert A
T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7770-7.
2008: Li Yongmei; Chen Fangqi; Putt Mary; Koo Yumee K; Madaio Michael; Cambier John C; Cohen Philip L; Eisenberg Robert A
B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):2961-72.
2008: Shao Wen-Hai; Eisenberg Robert A; Cohen Philip L
The Mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(11):7728-35.
2008: Ma Zhongjie; Choudhury Arpita; Kang Sun-Ah; Monestier Marc; Cohen Philip L; Eisenberg Robert A
Accelerated atherosclerosis in ApoE deficient lupus mouse models.
Clinical immunology (Orlando, Fla.) 2008;127(2):168-75.
2007: Choudhury Arpita; Cohen Philip L; Eisenberg Robert A
Mature B cells preferentially lose tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5564-70.
2006: Ma Zhongjie; Chen Fangqi; Madaio Michael P; Cohen Philip L; Eisenberg Robert A
Modulation of autoimmunity by TLR9 in the chronic graft-vs-host model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7444-50.
2006: Cohen Philip L
Apoptotic cell death and lupus.
Springer seminars in immunopathology 2006;28(2):145-52.
2005: Choudhury Arpita; Maldonado Michael A; Cohen Philip L; Eisenberg Robert A
The role of host CD4 T cells in the pathogenesis of the chronic graft-versus-host model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7600-9.
2005: Kuan Anita P; Cohen Philip L
p53 is required for spontaneous autoantibody production in B6/lpr lupus mice.
European journal of immunology 2005;35(5):1653-60.
2004: Cohen Philip L; Caricchio Roberto
Genetic models for the clearance of apoptotic cells.
Rheumatic diseases clinics of North America 2004;30(3):473-86, viii.
2003: Caricchio Roberto; McPhie Lenese; Cohen Philip L
Ultraviolet B radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5778-86.
2003: Behrens Edward M; Gadue Paul; Gong Shun-you; Garrett Stacey; Stein Paul L; Cohen Philip L
The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity.
European journal of immunology 2003;33(8):2160-7.
2003: Cohen Philip L; Maldonado Michael A
Animal models for SLE.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2003;Chapter 15():Unit 15.20.
2003: Suh Chang-Hee; Freed John H; Cohen Philip L
T cell reactivity to MHC class II-bound self peptides in systemic lupus erythematosus-prone MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):2229-35.
2003: Cohen Philip L
Studies of murine systemic autoimmunity.
Immunologic research 2003;27(2-3):179-84.
2002: Cohen Philip L
Autoimmunity and lymphoproliferation: two genes are worse than one.
Molecular interventions 2002;2(7):427-30.
2002: Parks Christine G; Cooper Glinda S; Nylander-French Leena A; Sanderson Wayne T; Dement John M; Cohen Philip L; Dooley Mary Anne; Treadwell Edward L; St Clair E William; Gilkeson Gary S; Hoppin Jane A; Savitz David A
Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States.
Arthritis and rheumatism 2002;46(7):1840-50.
2002: Cohen Philip L; Caricchio Roberto; Abraham Valsamma; Camenisch Todd D; Jennette J Charles; Roubey Robert A S; Earp H Shelton; Matsushima Glenn; Reap Elizabeth A
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
The Journal of experimental medicine 2002;196(1):135-40.
2002: Caricchio R; D'Adamio L; Cohen P L
Fas, ceramide and serum withdrawal induce apoptosis via a common pathway in a type II Jurkat cell line.
Cell death and differentiation 2002;9(5):574-80.
2002: Cooper G S; Parks C G; Treadwell E L; St Clair E W; Gilkeson G S; Cohen P L; Roubey R A S; Dooley M A
Differences by race, sex and age in the clinical and immunologic features of recently diagnosed systemic lupus erythematosus patients in the southeastern United States.
Lupus 2002;11(3):161-7.
2001: Scott R S; McMahon E J; Pop S M; Reap E A; Caricchio R; Cohen P L; Earp H S; Matsushima G K
Phagocytosis and clearance of apoptotic cells is mediated by MER.
Nature 2001;411(6834):207-11.
2000: Freed J H; Marrs A; VanderWall J; Cohen P L; Eisenberg R A
MHC class II-bound self peptides from autoimmune MRL/lpr mice reveal potential T cell epitopes for autoantibody production in murine systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4697-705.
1999: Caricchio R; Cohen P L
Spontaneous and induced apoptosis in systemic lupus erythematosus: multiple assays fail to reveal consistent abnormalities.
Cellular immunology 1999;198(1):54-60.
1999: Caricchio R; Kovalenko D; Kaufmann W K; Cohen P L
Apoptosis provoked by the oxidative stress inducer menadione (Vitamin K(3)) is mediated by the Fas/Fas ligand system.
Clinical immunology (Orlando, Fla.) 1999;93(1):65-74.
1999: Maldonado M A; MacDonald G C; Kakkanaiah V N; Fecho K; Dransfield M; Sekiguchi D; Cohen P L; Eisenberg R A
Differential control of autoantibodies and lymphoproliferation by Fas ligand expression on CD4+ and CD8+ T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3138-42.
1999: Weintraub J P; Cohen P L
Ectopic expression of B7-1 (CD80) on T lymphocytes in autoimmune lpr and gld mice.
Clinical immunology (Orlando, Fla.) 1999;91(3):302-9.
1999: Maldonado M A; Kakkanaiah V; MacDonald G C; Chen F; Reap E A; Balish E; Farkas W R; Jennette J C; Madaio M P; Kotzin B L; Cohen P L; Eisenberg R A
The role of environmental antigens in the spontaneous development of autoimmunity in MRL-lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6322-30.
1998: Booker J K; Reap E A; Cohen P L
Expression and function of Fas on cells damaged by gamma-irradiation in B6 and B6/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(9):4536-41.
1998: Fecho K; Cohen P L
Fas ligand (gld)- and Fas (lpr)-deficient mice do not show alterations in the extravasation or apoptosis of inflammatory neutrophils.
Journal of leukocyte biology 1998;64(3):373-83.
1998: Fecho K; Bentley S A; Cohen P L
Mice deficient in fas ligand (gld) or fas (lpr) show few alterations in granulopoiesis.
Cellular immunology 1998;188(1):19-32.
1998: Caricchio R; Reap E A; Cohen P L
Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):241-51.
1998: Weintraub J P; Godfrey V; Wolthusen P A; Cheek R L; Eisenberg R A; Cohen P L
Immunological and pathological consequences of mutations in both Fas and Fas ligand.
Cellular immunology 1998;186(1):8-17.
1998: Sobel E S; Kakkanaiah V N; Schiffenbauer J; Reap E A; Cohen P L; Eisenberg R A
Novel immunoregulatory B cell pathways revealed by lpr-+ mixed chimeras.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1497-503.
1998: Gangi-Peterson L; Peterson S N; Shapiro L H; Golding A; Caricchio R; Cohen D I; Margulies D H; Cohen P L
bca: an activation-related B-cell gene.
Molecular immunology 1998;35(1):55-63.
1997: Weintraub J P; Eisenberg R A; Cohen P L
Up-regulation of Fas and the costimulatory molecules B7-1 and B7-2 on peripheral lymphocytes in autoimmune B6/gld mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(8):4117-26.
1997: Kakkanaiah V N; Sobel E S; MacDonald G C; Cheek R L; Cohen P L; Eisenberg R A
B cell genotype determines the fine specificity of autoantibody in lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(2):1027-35.
1997: Reap E A; Roof K; Maynor K; Borrero M; Booker J; Cohen P L
Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5750-5.
1997: Reap E A; Roof K; Maynor K; Cohen P L
Markedly diminished radiation-induced lymphocyte apoptosis in lpr mice suggests a role for Fas in eliminating damaged cells.
Annals of the New York Academy of Sciences 1997;815():116-8.
1997: Cohen P L; Hadler N M; Starkenburg R
Acute intermittent porphyria presenting as acute muscle pain, fever, and weakness.
Arthritis and rheumatism 1997;40(3):586-7.
1996: Zajac A J; Quinn D G; Cohen P L; Frelinger J A
Fas-dependent CD4+ cytotoxic T-cell-mediated pathogenesis during virus infection.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14730-5.
1996: Retter M W; Cohen P L; Eisenberg R A; Clarke S H
Both Sm and DNA are selecting antigens in the anti-Sm B cell response in autoimmune MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1296-306.
1996: Kakkanaiah V N; MacDonald G C; Cohen P L; Eisenberg R A
Suppression and reversal of gld disease by parabiosis with normal mice.
Clinical immunology and immunopathology 1996;78(1):6-13.
1996: Reap E A; Piecyk M L; Oliver A; Sobel E S; Waldschmidt T; Cohen P L; Eisenberg R A
Phenotypic abnormalities of splenic and bone marrow B cells in lpr and gld mice.
Clinical immunology and immunopathology 1996;78(1):21-9.
1996: Creech E A; Nakul-Aquaronne D; Reap E A; Cheek R L; Wolthusen P A; Cohen P L; Eisenberg R A
MHC genes modify systemic autoimmune disease. The role of the I-E locus.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):812-7.
1995: Reap E A; Felix N J; Wolthusen P A; Kotzin B L; Cohen P L; Eisenberg R A
bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5455-62.
1995: Retter M W; Eisenberg R A; Cohen P L; Clarke S H
Sm and DNA binding by dual reactive B cells requires distinct VH, V kappa, and VH CDR3 structures.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(4):2248-57.
1995: Sobel E S; Kakkanaiah V N; Rapoport R G; Eisenberg R A; Cohen P L
The abnormal lpr double-negative T cell fails to proliferate in vivo.
Clinical immunology and immunopathology 1995;74(2):177-84.
1995: Maldonado M A; Eisenberg R A; Roper E; Cohen P L; Kotzin B L
Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I.
The Journal of experimental medicine 1995;181(2):641-8.
1995: Reap E A; Leslie D; Abrahams M; Eisenberg R A; Cohen P L
Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):936-43.
1995: Sobel E S; Kakkanaiah V N; Kakkanaiah M; Cohen P L; Eisenberg R A
Co-infusion of normal bone marrow partially corrects the gld T-cell defect. Evidence for an intrinsic and extrinsic role for Fas ligand.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(1):459-64.
1995: MacDonald G C; Kakkanaiah V N; Sobel E S; Cohen P L; Eisenberg R A
In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(1):444-9.
1994: Sobel E S; Kakkanaiah V N; Kakkanaiah M; Cheek R L; Cohen P L; Eisenberg R A
T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):6011-6.
1994: Eisenberg R A; Sobel E S; Reap E A; Halpern M D; Cohen P L
The role of B cell abnormalities in the systemic autoimmune syndromes of lpr and gld mice.
Seminars in immunology 1994;6(1):49-54.
1994: Bradley D S; Jennette J C; Cohen P L; Eisenberg R A
Chronic graft versus host disease-associated autoimmune manifestations are independently regulated by different MHC class II loci.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(4):1960-9.
1993: Halpern M D; Craven S Y; Cohen P L; Eisenberg R A
Regulation of anti-Sm autoantibodies by the immunoglobulin heavy chain locus.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):7268-72.
1993: Reap E A; Sobel E S; Jennette J C; Cohen P L; Eisenberg R A
Conventional B cells, not B1 cells, are the source of autoantibodies in chronic graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):7316-23.
1993: Sobel E S; Kakkanaiah V N; Cohen P L; Eisenberg R A
Correction of gld autoimmunity by co-infusion of normal bone marrow suggests that gld is a mutation of the Fas ligand gene.
International immunology 1993;5(10):1275-8.
1993: Cohen P L; Creech E; Nakul-Aquaronne D; McDaniel R; Ackler S; Rapoport R G; Sobel E S; Eisenberg R A
Antigen nonspecific effect of major histocompatibility complex haplotype on autoantibody levels in systemic lupus erythematosus-prone lpr mice.
The Journal of clinical investigation 1993;91(6):2761-8.
1993: Sobel E S; Cohen P L; Eisenberg R A
lpr T cells are necessary for autoantibody production in lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(9):4160-7.
1993: Bloom D D; Davignon J L; Retter M W; Shlomchik M J; Pisetsky D S; Cohen P L; Eisenberg R A; Clarke S H
V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1591-610.
1993: Bloom D D; Davignon J L; Cohen P L; Eisenberg R A; Clarke S H
Overlap of the anti-Sm and anti-DNA responses of MRL/Mp-lpr/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1579-90.
1993: Reap E A; Sobel E S; Cohen P L; Eisenberg R A
Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice.
The Journal of experimental medicine 1993;177(1):69-78.
1993: Sobel E S; Yokoyama W M; Shevach E M; Eisenberg R A; Cohen P L
Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(2):673-82.
1992: Halpern M D; Fisher C L; Cohen P L; Eisenberg R A
Influence of the Ig H chain locus on autoantibody production in autoimmune mice.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(11):3735-40.
1992: Cohen P L; Eisenberg R A
The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane.
Immunology today 1992;13(11):427-8.
1992: Reap E A; Sobel E S; Cohen P L; Eisenberg R A
The role of CD5+ B cells in the production of autoantibodies in murine systemic lupus erythematosus.
Annals of the New York Academy of Sciences 1992;651():588-90.
1992: Croghan T W; Rapaport R; Frelinger J S; Eisenberg R A; Cohen P L
Clonal analysis of peripheral T cell precursors in lpr mice.
Autoimmunity 1992;12(4):295-302.
1991: Davignon J L; Arnold L W; Cohen P L; Eisenberg R A
CD3 expression, modulation and signalling in T-cell subpopulations from MRL/Mp-lpr/lpr mice.
Journal of autoimmunity 1991;4(6):831-44.
1991: Sobel E S; Katagiri T; Katagiri K; Morris S C; Cohen P L; Eisenberg R A
An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity.
The Journal of experimental medicine 1991;173(6):1441-9.
1991: Davignon J L; Vallin-Davignon M; Cohen P L; Eisenberg R A
Targeting of T-B interaction using heteroconjugate antibody.
Immunology 1991;73(1):1-7.
1991: Cohen P L; Eisenberg R A
Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease.
Annual review of immunology 1991;9():243-69.
1990: Morris S C; Cohen P L; Eisenberg R A
Experimental induction of systemic lupus erythematosus by recognition of foreign Ia.
Clinical immunology and immunopathology 1990;57(2):263-73.
1990: Morris S C; Cheek R L; Cohen P L; Eisenberg R A
Autoantibodies in chronic graft versus host result from cognate T-B interactions.
The Journal of experimental medicine 1990;171(2):503-17.
1990: Morris S C; Cheek R L; Cohen P L; Eisenberg R A
Allotype-specific immunoregulation of autoantibody production by host B cells in chronic graft-versus host disease.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):916-22.
1990: Eisenberg R A; Pisetsky D S; Craven S Y; Grudier J P; O'Donnell M A; Cohen P L
Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies.
The Journal of clinical investigation 1990;85(1):86-92.
1989: Eisenberg R A; Craven S Y; Fisher C L; Morris S C; Rapoport R; Pisetsky D S; Cohen P L
The genetics of autoantibody production in MRL/lpr lupus mice.
Clinical and experimental rheumatology 1989;7 Suppl 3():S35-40.
1989: Fisher C L; Shores E W; Eisenberg R A; Cohen P L
Cellular interactions for the in vitro production of anti-chromatin autoantibodies in MRL/Mp-lpr/lpr mice.
Clinical immunology and immunopathology 1989;50(2):231-40.
1989: Groghan T W; Davignon J L; Evans J; Allison J P; Eisenberg R A; Frelinger J A; Cohen P L
Diminished expression of the T cell receptor on the expanded lymphocyte population in MRL/Mp-lpr/lpr mice.
Autoimmunity 1989;2(2):97-111.
1988: Shores E W; Pisetsky D S; Grudier J; Eisenberg R A; Cohen P L
Immunization with the Sm nuclear antigen induces anti-Sm antibodies in normal and MRL mice.
Immunology 1988;65(3):473-8.
1988: Davignon J L; Cohen P L; Eisenberg R A
Rapid T cell receptor modulation accompanies lack of in vitro mitogenic responsiveness of double negative T cells to anti-CD3 monoclonal antibody in MRL/Mp-lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(6):1848-54.
1988: Shores E W; Eisenberg R A; Cohen P L
T-B collaboration in the in vitro anti-Sm autoantibody response of MRL/Mp-lpr/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):2977-82.
1988: Katagiri T; Cohen P L; Eisenberg R A
The lpr gene causes an intrinsic T cell abnormality that is required for hyperproliferation.
The Journal of experimental medicine 1988;167(3):741-51.
1988: Katagiri T; Schepart B; Croghan T W; Frelinger J A; Eisenberg R A; Cohen P L
Southern blot analysis of major histocompatibility genes of lpr mice.
Experimental and clinical immunogenetics 1988;5(4):218-25.

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