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Patricia Cohen

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Margarida Fardilha; Luís Korrodi-Gregório; Nick Morrice; Sandra Rebelo; Ana Paula Vintém; Patricia T W Cohen; Sara C T S Domingues; Sara L C Esteves; Odete A B da Cruz e Silva; Edgar F da Cruz e Silva
Identification of the human testis protein phosphatase 1 interactome.
Martin Voss; James Paterson; Ian R Kelsall; Cristina Martín-Granados; C James Hastie; Mark W Peggie; Patricia T W Cohen
Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
Ian R Kelsall; Doron Rosenzweig; Patricia T W Cohen
Disruption of the allosteric phosphorylase a regulation of the hepatic glycogen-targeted protein phosphatase 1 improves glucose tolerance in vivo.

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All Publications

2011: Margarida Fardilha; Luís Korrodi-Gregório; Nick Morrice; Sandra Rebelo; Ana Paula Vintém; Patricia T W Cohen; Sara C T S Domingues; Sara L C Esteves; Odete A B da Cruz e Silva; Edgar F da Cruz e Silva
Identification of the human testis protein phosphatase 1 interactome.
Biochemical pharmacology 2011;82(10):1403-15.
2011: Martin Voss; James Paterson; Ian R Kelsall; Cristina Martín-Granados; C James Hastie; Mark W Peggie; Patricia T W Cohen
Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
Cellular signalling 2011;23(1):114-24.
2009: Ian R Kelsall; Doron Rosenzweig; Patricia T W Cohen
Disruption of the allosteric phosphorylase a regulation of the hepatic glycogen-targeted protein phosphatase 1 improves glucose tolerance in vivo.
Cellular signalling 2009;21(7):1123-34.
2008: Cristina Vázquez-Martin; John Rouse; Patricia T W Cohen
Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage.
The FEBS journal 2008;275(16):4211-21.
2008: James Paterson; Ian R Kelsall; Patricia T W Cohen
Disruption of the striated muscle glycogen-targeting subunit of protein phosphatase 1: influence of the genetic background.
Journal of molecular endocrinology 2008;40(2):47-59.
2008: Cristina Martin-Granados; Amanda Philp; Senga K Oxenham; Alan R Prescott; Patricia T W Cohen
Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases.
The international journal of biochemistry & cell biology 2008;40(10):2315-32.
2007: Ian R Kelsall; Shonagh Munro; Irene Hallyburton; Judith L Treadway; Patricia T W Cohen
The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug.
FEBS letters 2007;581(24):4749-53.
2007: Barry J Toole; Patricia T W Cohen
The skeletal muscle-specific glycogen-targeted protein phosphatase 1 plays a major role in the regulation of glycogen metabolism by adrenaline in vivo.
Cellular signalling 2007;19(5):1044-55.
2007: Gareth J Browne; Margarida Fardilha; Senga K Oxenham; Wenjuan Wu; Nicholas R Helps; Odete A B da Cruz e Silva; Patricia T W Cohen; Edgar F da Cruz e Silva
SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein.
The Biochemical journal 2007;402(1):187-96.
2006: C James Hastie; Cristina Vázquez-Martin; Amanda Philp; Michael J R Stark; Patricia T W Cohen
The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin.
The FEBS journal 2006;273(14):3322-34.
2005: C James Hastie; Emma B Borthwick; Louise F Morrison; Geoffrey A Codd; Patricia T W Cohen
Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin.
Biochimica et biophysica acta 2005;1726(2):187-93.
2005: Patricia T W Cohen; Amanda Philp; Cristina Vázquez-Martin
Protein phosphatase 4--from obscurity to vital functions.
FEBS letters 2005;579(15):3278-86.
2005: Shonagh Munro; Hugo Ceulemans; Mathieu Bollen; Julie Diplexcito; Patricia T W Cohen
A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents.
The FEBS journal 2005;272(6):1478-89.
2005: Jing Yang; S Mark Roe; Matthew J Cliff; Mark A Williams; John E Ladbury; Patricia T W Cohen; David Barford
Molecular basis for TPR domain-mediated regulation of protein phosphatase 5.
The EMBO journal 2005;24(1):1-10.
2005: Tamás Zeke; Nick Morrice; Cristina Vázquez-Martin; Patricia T W Cohen
Human protein phosphatase 5 dissociates from heat-shock proteins and is proteolytically activated in response to arachidonic acid and the microtubule-depolymerizing drug nocodazole.
The Biochemical journal 2005;385(Pt 1):45-56.
2003: Alex S F Doney; Bettina Fischer; Joanne E Cecil; Patricia T W Cohen; Douglas I Boyle; Graham P Leese; Andrew D Morris; Colin N A Palmer
Male preponderance in early diagnosed type 2 diabetes is associated with the ARE insertion/deletion polymorphism in the PPP1R3A locus.
BMC genetics 2003;4():11.
2003: Graeme Carnegie; Judith E Sleeman; Nick Morrice; C James Hastie; Mark Peggie; Amanda Philp; Angus I Lamond; Patricia T W Cohen
Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs.
Journal of cell science 2003;116(Pt 10):1905-13.
2003: Mirela Delibegovic; Christopher G Armstrong; Lorraine Dobbie; Peter W Watt; Andrew J H Smith; Patricia T W Cohen
Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance.
Diabetes 2003;52(3):596-604.
2003: Patricia T W Cohen; Gareth J Browne; Mirela Delibegovic; Shonagh Munro
Assay of protein phosphatase 1 complexes.
Methods in enzymology 2003;366():135-44.
2002: Shonagh Munro; Daniel J Cuthbertson; Joan Cunningham; Mark Sales; Patricia T W Cohen
Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver.
Diabetes 2002;51(3):591-8.
2002: Patricia T W Cohen
Protein phosphatase 1--targeted in many directions.
Journal of cell science 2002;115(Pt 2):241-56.
2001: Gareth J Browne; Mirela Delibegovic; Stefaan Keppens; Willy Stalmans; Patricia T W Cohen
The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats.
The Biochemical journal 2001;360(Pt 2):449-59.
2001: Emma B Borthwick; Tamás Zeke; A R Prescott; Patricia T W Cohen
Nuclear localization of protein phosphatase 5 is dependent on the carboxy-terminal region.
FEBS letters 2001;491(3):279-84.
2001: Nicholas R Helps; Patricia T W Cohen; Sami Bahri; William Chia; Kavita Babu
Interaction with protein phosphatase 1 Is essential for bifocal function during the morphogenesis of the Drosophila compound eye.
Molecular and cellular biology 2001;21(6):2154-64.
2000: L Brown; Emma B Borthwick; Patricia T W Cohen
Drosophila protein phosphatase 5 is encoded by a single gene that is most highly expressed during embryonic development.
Biochimica et biophysica acta 2000;1492(2-3):470-6.
2000: Nicholas R Helps; X Luo; H M Barker; Patricia T W Cohen
NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.
The Biochemical journal 2000;349(Pt 2):509-18.
2000: John H Connor; D Frederick; H b Huang; Jinzeng Yang; Nicholas R Helps; Patricia T W Cohen; Angus Nairn; A DePaoli-Roach; Kelly Tatchell; Shirish Shenolikar
Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit.
The Journal of biological chemistry 2000;275(25):18670-5.
2000: C James Hastie; Graeme Carnegie; Nick Morrice; Patricia T W Cohen
A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres.
The Biochemical journal 2000;347 Pt 3():845-55.
2000: Paul Ajuh; Gareth J Browne; Nicola A Hawkes; Patricia T W Cohen; Stefan G E Roberts; Angus I Lamond
Association of a protein phosphatase 1 activity with the human factor C1 (HCF) complex.
Nucleic acids research 2000;28(3):678-86.
1999: Nicholas R Helps; Patricia T W Cohen
Drosophila melanogaster protein phosphatase inhibitor-2: identification of a site important for PP1 inhibition.
FEBS letters 1999;463(1-2):72-6.
1998: Christopher G Armstrong; M J Doherty; Patricia T W Cohen
Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1.
The Biochemical journal 1998;336 ( Pt 3)():699-704.
1998: Nicholas R Helps; C Vergidou; T Gaskell; Patricia T W Cohen
Characterisation of a novel Drosophila melanogaster testis specific PP1 inhibitor related to mammalian inhibitor-2: identification of the site of interaction with PP1.
FEBS letters 1998;438(1-2):131-6.
1998: Christopher G Armstrong; V Dombradi; D J Mann; Patricia T W Cohen
Cloning of a novel testis specific protein serine/threonine phosphatase, PPN 58A, from Drosophila melanogaster.
Biochimica et biophysica acta 1998;1399(2-3):234-8.
1998: C James Hastie; Patricia T W Cohen
Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters.
FEBS letters 1998;431(3):357-61.
1998: M J Doherty; Joan Cadefau; Willy Stalmans; Mathieu Bollen; Patricia T W Cohen
Loss of the hepatic glycogen-binding subunit (GL) of protein phosphatase 1 underlies deficient glycogen synthesis in insulin-dependent diabetic rats and in adrenalectomized starved rats.
The Biochemical journal 1998;333 ( Pt 2)():253-7.
1998: Nicholas R Helps; N D Brewis; K Lineruth; T Davis; K Kaiser; Patricia T W Cohen
Protein phosphatase 4 is an essential enzyme required for organisation of microtubules at centrosomes in Drosophila embryos.
Journal of cell science 1998;111 ( Pt 10)():1331-40.
1997: Christopher G Armstrong; Gareth J Browne; Philip Cohen; Patricia T W Cohen
PPP1R6, a novel member of the family of glycogen-targetting subunits of protein phosphatase 1.
FEBS letters 1997;418(1-2):210-4.
1997: Patricia T W Cohen
Novel protein serine/threonine phosphatases: variety is the spice of life.
Trends in biochemical sciences 1997;22(7):245-51.
1997: M P Egloff; D F Johnson; G Moorhead; Patricia T W Cohen; Philip Cohen; David Barford
Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1.
The EMBO journal 1997;16(8):1876-87.
1997: D Johnson; Philip Cohen; M X Chen; Y H Chen; Patricia T W Cohen
Identification of the regions on the M110 subunit of protein phosphatase 1M that interact with the M21 subunit and with myosin.
European journal of biochemistry / FEBS 1997;244(3):931-9.
1997: M X Chen; Patricia T W Cohen
Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain.
FEBS letters 1997;400(1):136-40.
1996: A K Das; Nicholas R Helps; Patricia T W Cohen; David Barford
Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution.
The EMBO journal 1996;15(24):6798-809.
1996: M J Doherty; Peter Young; Patricia T W Cohen
Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1.
FEBS letters 1996;399(3):339-43.
1996: H A Snaith; Christopher G Armstrong; Y Guo; K Kaiser; Patricia T W Cohen
Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos.
Journal of cell science 1996;109 ( Pt 13)():3001-12.
1996: Carol MacKintosh; A J Garton; A McDonnell; D Barford; Patricia T W Cohen; N K Tonks; Philip Cohen
Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation.
FEBS letters 1996;397(2-3):235-8.
1996: D F Johnson; Greg B G Moorhead; F B Caudwell; Philip Cohen; Y H Chen; M X Chen; Patricia T W Cohen
Identification of protein-phosphatase-1-binding domains on the glycogen and myofibrillar targetting subunits.
European journal of biochemistry / FEBS 1996;239(2):317-25.
1996: Patricia T W Cohen; M X Chen; Christopher G Armstrong
Novel protein phosphatases that may participate in cell signaling.
Advances in pharmacology (San Diego, Calif.) 1996;36():67-89.
1995: SP Davies; Nicholas R Helps; Patricia T W Cohen; D Grahame Hardie
5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.
FEBS letters 1995;377(3):421-5.
1995: Nicholas R Helps; H M Barker; S J Elledge; Patricia T W Cohen
Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53.
FEBS letters 1995;377(3):295-300.
1995: M P Egloff; Patricia T W Cohen; P Reinemer; David Barford
Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate.
Journal of molecular biology 1995;254(5):942-59.
1995: M J Doherty; Greg B G Moorhead; Nick Morrice; Philip Cohen; Patricia T W Cohen
Amino acid sequence and expression of the hepatic glycogen-binding (GL)-subunit of protein phosphatase-1.
FEBS letters 1995;375(3):294-8.
1995: I A Leighton; K N Dalby; F B Caudwell; Patricia T W Cohen; Philip Cohen
Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation.
FEBS letters 1995;375(3):289-93.
1995: Christopher G Armstrong; D J Mann; Norbert Berndt; Patricia T W Cohen
Drosophila PPY, a novel male specific protein serine/threonine phosphatase localised in somatic cells of the testis.
Journal of cell science 1995;108 ( Pt 11)():3367-75.
1995: R W MacKintosh; K N Dalby; D G Campbell; Patricia T W Cohen; Philip Cohen; Carol MacKintosh
The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.
FEBS letters 1995;371(3):236-40.
1994: Y H Chen; M X Chen; Dario R Alessi; D G Campbell; C Shanahan; Philip Cohen; Patricia T W Cohen
Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M.
FEBS letters 1994;356(1):51-5.
1994: Y H Chen; Lars Hansen; M X Chen; C Bjørbaek; Henrik Vestergaard; Torben Hansen; Patricia T W Cohen; Oluf Pedersen
Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM.
Diabetes 1994;43(10):1234-41.
1994: M X Chen; A E McPartlin; L Brown; Y H Chen; H M Barker; Patricia T W Cohen
A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus.
The EMBO journal 1994;13(18):4278-90.
1994: Nicholas R Helps; A J Street; S J Elledge; Patricia T W Cohen
Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli.
FEBS letters 1994;340(1-2):93-8.
1994: G J Barton; Patricia T W Cohen; D Barford
Conservation analysis and structure prediction of the protein serine/threonine phosphatases. Sequence similarity with diadenosine tetraphosphatase from Escherichia coli suggests homology to the protein phosphatases.
European journal of biochemistry / FEBS 1994;220(1):225-37.
1994: L Brown; M X Chen; Patricia T W Cohen
Identification of a cDNA encoding a Drosophila calcium/calmodulin regulated protein phosphatase, which has its most abundant expression in the early embryo.
FEBS letters 1994;339(1-2):124-8.
1994: H M Barker; N D Brewis; A J Street; Nigel K Spurr; Patricia T W Cohen
Three genes for protein phosphatase 1 map to different human chromosomes: sequence, expression and gene localisation of protein serine/threonine phosphatase 1 beta (PPP1CB).
Biochimica et biophysica acta 1994;1220(2):212-8.
1993: David Stokoe; B Caudwell; Patricia T W Cohen; Philip Cohen
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2.
The Biochemical journal 1993;296 ( Pt 3)():843-9.
1993: M X Chen; Y H Chen; Patricia T W Cohen
PPQ, a novel protein phosphatase containing a Ser + Asn-rich amino-terminal domain, is involved in the regulation of protein synthesis.
European journal of biochemistry / FEBS 1993;218(2):689-99.
1993: D J Mann; V Dombrádi; Patricia T W Cohen
Drosophila protein phosphatase V functionally complements a SIT4 mutant in Saccharomyces cerevisiae and its amino-terminal region can confer this complementation to a heterologous phosphatase catalytic domain.
The EMBO journal 1993;12(12):4833-42.
1993: H M Barker; S P Craig; Nigel K Spurr; Patricia T W Cohen
Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q24.2.
Biochimica et biophysica acta 1993;1178(2):228-33.
1993: V Hughes; A Müller; Michael J R Stark; Patricia T W Cohen
Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress.
European journal of biochemistry / FEBS 1993;216(1):269-79.
1993: Dario R Alessi; A J Street; Philip Cohen; Patricia T W Cohen
Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme.
European journal of biochemistry / FEBS 1993;213(3):1055-66.
1993: N D Brewis; A J Street; Alan R Prescott; Patricia T W Cohen
PPX, a novel protein serine/threonine phosphatase localized to centrosomes.
The EMBO journal 1993;12(3):987-96.
1993: V Dombrádi; D J Mann; R D Saunders; Patricia T W Cohen
Cloning of the fourth functional gene for protein phosphatase 1 in Drosophila melanogaster from its chromosomal location.
European journal of biochemistry / FEBS 1993;212(1):177-83.
1993: T A Jones; H M Barker; E F da Cruz e Silva; R E Mayer-Jaekel; B A Hemmings; Nigel K Spurr; Denise Sheer; Patricia T W Cohen
Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively.
Cytogenetics and cell genetics 1993;63(1):35-41.
1992: N D Brewis; Patricia T W Cohen
Protein phosphatase X has been highly conserved during mammalian evolution.
Biochimica et biophysica acta 1992;1171(2):231-3.
1992: V Dombrádi; Patricia T W Cohen
Protein phosphorylation is involved in the regulation of chromatin condensation during interphase.
FEBS letters 1992;312(1):21-6.
1992: M X Chen; Y H Chen; Patricia T W Cohen
Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases.
FEBS letters 1992;306(1):54-8.
1992: D J Mann; D G Campbell; C H McGowan; Patricia T W Cohen
Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences.
Biochimica et biophysica acta 1992;1130(1):100-4.
1991: E F Da Cruz e Silva; V Hughes; P McDonald; Michael J R Stark; Patricia T W Cohen
Protein phosphatase 2Bw and protein phosphatase Z are Saccharomyces cerevisiae enzymes.
Biochimica et biophysica acta 1991;1089(2):269-72.
1991: A E McPartlin; H M Barker; Patricia T W Cohen
Identification of a third alternatively spliced cDNA encoding the catalytic subunit of protein phosphatase 2B beta.
Biochimica et biophysica acta 1991;1088(2):308-10.
1991: Patricia T W Cohen; Norbert Berndt
Reactivation of protein phosphatase 1 expressed at high levels from recombinant baculovirus.
Methods in enzymology 1991;201():408-14.
1990: V Dombrádi; Myles Axton; N D Brewis; E F da Cruz e Silva; Luke Alphey; Patricia T W Cohen
Drosophila contains three genes that encode distinct isoforms of protein phosphatase 1.
European journal of biochemistry / FEBS 1990;194(3):739-45.
1990: R W MacKintosh; G Haycox; D Grahame Hardie; Patricia T W Cohen
Identification by molecular cloning of two cDNA sequences from the plant Brassica napus which are very similar to mammalian protein phosphatases-1 and -2A.
FEBS letters 1990;276(1-2):156-60.
1990: A A Sneddon; Patricia T W Cohen; Michael J R Stark
Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes.
The EMBO journal 1990;9(13):4339-46.
1990: S Orgad; N D Brewis; Luke Alphey; Myles Axton; Yadin Dudai; Patricia T W Cohen
The structure of protein phosphatase 2A is as highly conserved as that of protein phosphatase 1.
FEBS letters 1990;275(1-2):44-8.
1990: V Dombrádi; Myles Axton; H M Barker; Patricia T W Cohen
Protein phosphatase 1 activity in Drosophila mutants with abnormalities in mitosis and chromosome condensation.
FEBS letters 1990;275(1-2):39-43.
1990: Myles Axton; V Dombrádi; Patricia T W Cohen; David M Glover
One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis.
Cell 1990;63(1):33-46.
1990: Patricia T W Cohen; N D Brewis; V Hughes; D J Mann
Protein serine/threonine phosphatases; an expanding family.
FEBS letters 1990;268(2):355-9.
1990: Norbert Berndt; Patricia T W Cohen
Renaturation of protein phosphatase 1 expressed at high levels in insect cells using a baculovirus vector.
European journal of biochemistry / FEBS 1990;190(2):291-7.
1990: H M Barker; T A Jones; E F da Cruz e Silva; Nigel K Spurr; Denise Sheer; Patricia T W Cohen
Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.
Genomics 1990;7(2):159-66.
1990: T A Jones; E F da Cruz e Silva; Nigel K Spurr; Denise Sheer; Patricia T W Cohen
Localisation of the gene encoding the catalytic gamma subunit of phosphorylase kinase to human chromosome bands 7p12-q21.
Biochimica et biophysica acta 1990;1048(1):24-9.
1989: E F da Cruz e Silva; Patricia T W Cohen
Isolation of a cDNA likely to encode a novel Ca2+-dependent/calmodulin-stimulated protein phosphatase.
Biochimica et biophysica acta 1989;1009(3):293-6.
1989: V Dombrádi; Myles Axton; David M Glover; Patricia T W Cohen
Cloning and chromosomal localization of Drosophila cDNA encoding the catalytic subunit of protein phosphatase 1 alpha. High conservation between mammalian and insect sequences.
European journal of biochemistry / FEBS 1989;183(3):603-10.
1989: L R Chen; C J Yuan; G Somasekhar; P Wejksnora; J E Peterson; A M Myers; Lee M Graves; Patricia T W Cohen; E F da Cruz e Silva; Donald J Graves
Expression and characterization of the tau subunit of phosphorylase kinase.
Biochemical and biophysical research communications 1989;161(2):746-53.
1989: Patricia T W Cohen; Philip Cohen
Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221.
The Biochemical journal 1989;260(3):931-4.
1989: Patricia T W Cohen; D L Schelling; O B da Cruz e Silva; H M Barker; Philip Cohen
The major type-1 protein phosphatase catalytic subunits are the same gene products in rabbit skeletal muscle and rabbit liver.
Biochimica et biophysica acta 1989;1008(1):125-8.
1989: V Dombrádi; Myles Axton; David M Glover; Patricia T W Cohen
Molecular cloning and chromosomal localization of a novel Drosophila protein phosphatase.
FEBS letters 1989;247(2):391-5.
1988: O B da Cruz e Silva; E F da Cruz e Silva; Patricia T W Cohen
Identification of a novel protein phosphatase catalytic subunit by cDNA cloning.
FEBS letters 1988;242(1):106-10.
1988: Patricia T W Cohen; J F Collins; A F Coulson; Norbert Berndt; O B da Cruz e Silva
Segments of bacteriophage lambda (orf 221) and phi 80 are homologous to genes coding for mammalian protein phosphatases.
Gene 1988;69(1):131-4.
1988: Patricia T W Cohen
Two isoforms of protein phosphatase 1 may be produced from the same gene.
FEBS letters 1988;232(1):17-23.
1988: Patricia T W Cohen; Norbert Berndt; O da Cruz e Silva; D G Campbell
Homology between the catalytic subunits of protein phosphatases 1 and 2A deduced from the cDNA.
Advances in experimental medicine and biology 1988;231():549-57.
1987: O B da Cruz e Silva; Patricia T W Cohen
A second catalytic subunit of type-2A protein phosphatase from rabbit skeletal muscle.
FEBS letters 1987;226(1):176-8.
1987: Norbert Berndt; D G Campbell; F B Caudwell; Philip Cohen; E F da Cruz e Silva; O B da Cruz e Silva; Patricia T W Cohen
Isolation and sequence analysis of a cDNA clone encoding a type-1 protein phosphatase catalytic subunit: homology with protein phosphatase 2A.
FEBS letters 1987;223(2):340-6.
1987: O B da Cruz e Silva; S Alemany; D G Campbell; Patricia T W Cohen
Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of a type-2A protein phosphatase.
FEBS letters 1987;221(2):415-22.
1987: E F da Cruz e Silva; Patricia T W Cohen
Isolation and sequence analysis of a cDNA clone encoding the entire catalytic subunit of phosphorylase kinase.
FEBS letters 1987;220(1):36-42.