Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Howard Colby
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Living Beings
Anatomy
Chemicals & Drugs
Procedures
Sign-in to see full Profile
Network (preview)
13
Voigt, JM
6
Longhurst, Penelope
5
Hayes, Jill
4
Burczynski, Joseph
4
Yuan, Bing-Bing
3
Tchao, Ruy
2
Ramjit, Harri
1
Pitzenberger, Steven
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Howard Colby (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2003: Colby Howard D; Longhurst Penelope A; Burczynski Joseph M; Hayes Jill R; Yuan Bing-Bing; Voigt Jeffrey V
Downregulation of CYP2D16 by ACTH in the guinea pig adrenal cortex: time course, reversibility, and mechanism of action.
Pharmacology 2003;67(3):121-7.
-
2001: Colby H D; Nowak D M; Longhurst P A; Zhang X; Hayes J R; Voigt J M
Bufuralol metabolism by guinea pig adrenal and hepatic microsomes.
Pharmacology 2001;62(4):229-33.
-
2001: Burczynski J M; Southard S J; Hayes J R; Longhurst P A; Colby H D
Changes in mitochondrial and microsomal lipid peroxidation and fatty acid profiles in adrenal glands, testes, and livers from alpha-tocopherol-deficient rats.
Free radical biology & medicine 2001;30(9):1029-35.
-
2001: Burczynski J M; Hayes J R; Voigt J M; Longhurst P A; Colby H D
Suppression of lipid peroxidation in adrenal microsomes following ACTH administration to guinea pigs.
The Journal of endocrinology 2001;168(2):333-8.
-
2001: Yuan B B; Tchao R; Voigt J M; Colby H D
Maturational changes in CYP2D16 expression and xenobiotic metabolism in adrenal glands from male and female guinea pigs.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(2):194-9.
-
2000: Colby H D; Huang Y; Jiang Q; Voigt J M
Bimodal expression of CYP2D16 in the guinea pig adrenal cortex.
Pharmacology 2000;61(2):78-82.
-
1999: Burczynski J M; Hayes J R; Longhurst P A; Colby H D
Species differences in adrenal lipid peroxidation: role of alpha-tocopherol.
Free radical biology & medicine 1999;26(7-8):987-91.
-
1999: Feingold I B; Longhurst P A; Colby H D
Effects of adrenocorticotropic hormone and dexamethasone on adrenal and hepatic alpha-tocopherol concentrations.
Free radical biology & medicine 1999;26(5-6):633-8.
-
1998: Yuan B B; Tchao R; Funae Y; Voigt J M; Colby H D
Effects of ACTH administration on zonation of the guinea pig adrenal cortex.
Molecular and cellular endocrinology 1998;146(1-2):129-36.
-
1998: Huang Y; Jiang Q; Debolt K M; Voigt J M; Colby H D
Strain differences in adrenal microsomal steroid metabolism in guinea pigs.
The Journal of steroid biochemistry and molecular biology 1998;64(5-6):305-11.
-
1998: Soltis M; Colby H D
Inhibition of testicular steroid metabolism by administration of 1-aminobenzotriazole to rats.
Pharmacology 1998;56(1):51-6.
-
1997: Yuan B B; Tchao R; Voigt J M; Colby H D
Localization of CYP2D16 in the guinea pig adrenal cortex by immunohistochemistry and in situ hybridization.
Molecular and cellular endocrinology 1997;134(2):139-46.
-
1996: Huang Y; Jiang Q; Voigt J M; Debolt K M; Colby H D
Strain differences in adrenal CYP2D16 expression in guinea pigs. Relationship to xenobiotic metabolism.
Biochemical pharmacology 1996;52(12):1925-9.
-
1996: Jiang Q; Huang Y; Voigt J M; DeBolt K M; Kominami S; Takemori S; Funae Y; Colby H D
Differential effects of adrenocorticotropin in vivo on cytochromes P4502D16 and P450c17 in the guinea pig adrenal cortex.
Endocrinology 1996;137(11):4811-6.
-
1996: Jiang Q; Huang Y; Voigt J M; DeBolt B K; Kominami S; Takemori S; Funae Y; Colby H D
Expression and zonal distribution of CYP2D16 in the guinea pig adrenal cortex: relationship to xenobiotic metabolism.
Molecular pharmacology 1996;49(3):458-64.
-
1996: Colby H D; LaCagnin L B; Los L E
Stimulation of microsomal spironolactone metabolism by reduced glutathione.
Pharmacology 1996;52(1):30-4.
-
1995: Xu D; Voigt J M; Mico B A; Colby H D
Inhibition of adrenal steroid metabolism by administration of 1-aminobenzotriazole to guinea pigs.
The Journal of steroid biochemistry and molecular biology 1995;54(5-6):281-5.
-
1995: Colby H D; Abbott B; Cachovic M; Debolt K M; Mico B A
Inactivation of adrenal cytochromes P450 by 1-aminobenzotriazole. Divergence of in vivo and in vitro actions.
Biochemical pharmacology 1995;49(8):1057-62.
-
1995: Jiang Q; Voigt J M; Colby H D
Molecular cloning and sequencing of a guinea pig cytochrome P4502D (CYP2D16): high level expression in adrenal microsomes.
Biochemical and biophysical research communications 1995;209(3):1149-56.
-
1995: Colby H D; Larson I W; Kowalski C; Levitt M
Zonal differences in adrenocortical lipid peroxidation: role of alpha-tocopherol.
Free radical biology & medicine 1995;18(2):373-6.
-
1994: Los L E; Pitzenberger S M; Ramjit H G; Coddington A B; Colby H D
Hepatic metabolism of spironolactone. Production of 3-hydroxy-thiomethyl metabolites.
Drug metabolism and disposition: the biological fate of chemicals 1994;22(6):903-8.
-
1994: Colby H D; Purcell H; Kominami S; Takemori S; Kossor D C
Adrenal activation of carbon tetrachloride: role of microsomal P450 isozymes.
Toxicology 1994;94(1-3):31-40.
-
1994: Xu D; Voigt J M; Mico B A; Kominami S; Takemori S; Colby H D
Inhibition of adrenal cytochromes P450 by 1-aminobenzotriazole in vitro. Selectivity for xenobiotic metabolism.
Biochemical pharmacology 1994;48(7):1421-6.
-
1994: Colby H D
In vitro assessment of adrenocortical toxicity.
Journal of pharmacological and toxicological methods 1994;32(1):1-6.
-
1994: Los L E; Colby H D
Binding of spironolactone metabolites in vivo to renal mineralocorticoid receptors in guinea pigs.
Pharmacology 1994;48(2):86-92.
-
1993: Los L E; Coddington A B; Ramjit H G; Colby H D
Identification of spironolactone metabolites in plasma and target organs of guinea pigs.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(6):1086-90.
-
1993: Colby H D; Levitt M; Bergstrom J M; Purcell H
Maturational changes in steroidogenesis in the inner and outer zones of the guinea pig adrenal cortex.
The Journal of steroid biochemistry and molecular biology 1993;45(6):501-7.
-
1993: Feingold I B; Longhurst P A; Colby H D
Regulation of adrenal and hepatic alpha-tocopherol content by androgens and estrogens.
Biochimica et biophysica acta 1993;1176(1-2):192-6.
-
1993: Colby H D; Levitt M; Larson I W
Zonal differences in the thermal lability of adrenal microsomal monooxygenases.
Drug metabolism and disposition: the biological fate of chemicals 1993;21(1):200-2.
-
1992: Kossor D C; Kominami S; Takemori S; Colby H D
Destruction of testicular cytochrome P-450 by 7 alpha-thiospironolactone is catalyzed by the 17 alpha-hydroxylase.
The Journal of steroid biochemistry and molecular biology 1992;42(3-4):421-4.
-
1992: Colby H D; Levitt M; Pope M R; Johnson P B
Differential effects of adrenocorticotropic hormone on steroid hydroxylase activities in the inner and outer zones of the guinea pig adrenal cortex.
The Journal of steroid biochemistry and molecular biology 1992;42(3-4):329-35.
-
1992: Feingold I B; Colby H D
Sex differences in adrenal and hepatic alpha-tocopherol concentrations in rats.
Pharmacology 1992;44(2):113-6.
-
1992: Kossor D C; Colby H D
Dose-dependent actions of spironolactone on the inner and outer zones of the guinea pig adrenal cortex.
Pharmacology 1992;45(1):27-33.
-
1991: Rourke K A; Bergstrom J M; Larson I W; Colby H D
Mechanism of action of spironolactone on cortisol production by guinea pig adrenocortical cells.
Molecular and cellular endocrinology 1991;81(1-3):127-34.
-
1991: Kossor D C; Kominami S; Takemori S; Colby H D
Role of the steroid 17 alpha-hydroxylase in spironolactone-mediated destruction of adrenal cytochrome P-450.
Molecular pharmacology 1991;40(2):321-5.
-
1991: Colby H D; Johnson P B; Pope M R
Mechanisms responsible for the thermal sensitivity of adrenal microsomal monooxygenases.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(3):679-82.
-
1991: Colby H D; O'Donnell J P; Flowers N L; Kossor D C; Johnson P B; Levitt M
Relationship between covalent binding to microsomal protein and the destruction of adrenal cytochrome P-450 by spironolactone.
Toxicology 1991;67(2):143-54.
-
1990: Rourke K A; Colby H D
Spironolactone inhibition of cortisol production by guinea pig adrenocortical cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1990;22(11):573-5.
-
1990: Staats D A; Lohr D P; Colby H D
Effects of carbon tetrachloride administration to guinea pigs on cytochromes P-450 and antioxidant levels in the inner and outer zones of the adrenal cortex.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(4):543-5.
-
1989: Sherry J H; Johnson P B; Levitt M; Bergstrom J; Colby H D
Regional differences in adrenal activation of spironolactone: relationship to steroid 17 alpha-hydroxylase activity.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(6):709-10.
-
1989: LaCagnin L B; Levitt M; Bergstrom J M; Colby H D
Inhibition of adrenocortical, mitochondrial and microsomal monooxygenases by SU-10'603, a steroid 17 alpha-hydroxylase inhibitor.
Journal of steroid biochemistry 1989;33(4A):599-604.
-
1989: Staats D A; Lohr D P; Colby H D
alpha-Tocopherol depletion eliminates the regional differences in adrenal mitochondrial lipid peroxidation.
Molecular and cellular endocrinology 1989;62(2):189-95.
-
1989: Staats D A; Colby H D
Modulation of the effects of ascorbic acid on lipid peroxidation by tocopherol in adrenocortical mitochondria.
Journal of steroid biochemistry 1989;32(4):609-11.
-
1989: Flowers N L; O'Donnell J P; Colby H D
Spironolactone metabolism in target tissues. Characteristics of deacetylation in kidney, liver, adrenal cortex, and testes.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(2):186-9.
-
1988: Staats D A; Lohr D; Colby H D
Relationship between mitochondrial lipid peroxidation and alpha-tocopherol levels in the guinea-pig adrenal cortex.
Biochimica et biophysica acta 1988;961(3):279-84.
-
1988: Staats D A; Lohr D P; Colby H D
Effects of tocopherol depletion on the regional differences in adrenal microsomal lipid peroxidation and steroid metabolism.
Endocrinology 1988;123(2):975-80.
-
1988: Colby H D; Lacagnin L B; Longhurst P A
Changes in adrenocortical monooxygenase activities in alloxan-diabetic rabbits.
Journal of steroid biochemistry 1988;29(6):731-3.
-
1988: LaCagnin L B; Patricoski P; Colby H D
Inhibition of hepatic microsomal drug metabolism by the steroid hydroxylase inhibitor SU-10'603.
Biochemical pharmacology 1988;37(8):1625-8.
-
1988: Flowers N L; Sherry J H; O'Donnell J P; Colby H D
Adrenal mitochondrial metabolism of spironolactone. Absence of metabolic activation.
Biochemical pharmacology 1988;37(8):1591-5.
-
1988: Sherry J H; Johnson P B; Colby H D
Species differences in adrenal spironolactone metabolism: relationship to cytochrome P-450 destruction.
Biochemical pharmacology 1988;37(2):355-7.
-
1987: Staats D A; Colby H D
Regional differences in microsomal lipid peroxidation and antioxidant levels in the guinea pig adrenal cortex.
Journal of steroid biochemistry 1987;28(6):637-42.
-
1987: LaCagnin L B; Lutsie P; Colby H D
Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes.
Biochemical pharmacology 1987;36(20):3439-44.
-
1987: LaCagnin L B; Colby H D; Dalal N S; O'Donnell J P
Metabolic activation of hydralazine by rat liver microsomes.
Biochemical pharmacology 1987;36(16):2667-72.
-
1987: Colby H D; Pope M R; Johnson P B; Sherry J H
Effects of cadmium in vitro on microsomal steroid metabolism in the inner and outer zones of the guinea pig adrenal cortex.
Journal of biochemical toxicology 1987;2():1-11.
-
1986: LaCagnin L B; Colby H D; O'Donnell J P
The oxidative metabolism of hydralazine by rat liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 1986;14(5):549-54.
-
1986: Longhurst P A; LaCagnin L B; Staats D A; Colby H D
Changes in hepatic drug metabolism in alloxan-diabetic male rabbits.
Biochemical pharmacology 1986;35(10):1768-71.
-
1986: Lacagnin L B; Colby H D; O'Donnell J P
Separation and quantitation of hydralazine metabolites by high-performance liquid chromatography.
Journal of chromatography 1986;377():319-27.
-
1986: Sherry J H; O'Donnell J P; Flowers L; Lacagnin L B; Colby H D
Metabolism of spironolactone by adrenocortical and hepatic microsomes: relationship to cytochrome P-450 destruction.
The Journal of pharmacology and experimental therapeutics 1986;236(3):675-80.
-
1986: Sherry J H; O'Donnell J P; Colby H D
Separation of spironolactone and its biologically active sulfur-containing metabolites by high-performance liquid chromatography.
Journal of chromatography 1986;374(1):183-90.
-
1985: Colby H D; Pope M R; Zulkoski J S; Eacho P I
Strain differences in microsomal xenobiotic metabolism by adrenocortical inner and outer zones.
Drug metabolism and disposition: the biological fate of chemicals 1985;13(3):371-3.
-
1984: Eacho P I; Johnson P B; Pope M R; Colby H D
Regional differences in adrenocortical benzo[a]pyrene metabolism in guinea pigs.
Biochemical pharmacology 1984;33(11):1811-3.
-
1984: Colby H D; Zulkoski J S; Johnson P B; Pope M R; Miles P R
Sites of action of cadmium in vitro on hepatic, adrenal, and pulmonary microsomal monooxygenases in guinea pigs.
Toxicology and applied pharmacology 1984;73(1):110-8.
-
1983: Colby H D; Zulkoski J S; Johnson P B; Pope M R; Miles P R
The duration of exposure of microsomal preparations to cadmium or zinc in vitro influences the inhibition of mono-oxygenases.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(1):67-9.
-
1982: Colby H D; Johnson P B; Zulkoski J S; Pope M R
Differential effects of adrenocorticotropic hormone on adrenal microsomal xenobiotic and steroid metabolism in guinea pigs.
Drug metabolism and disposition: the biological fate of chemicals 1982;10(4):326-9.
-
1982: Colby H D; Johnson P B; Pope M R; Zulkoski J S
Metabolism of benzo [a] pyrene by guinea pig adrenal and hepatic microsomes.
Biochemical pharmacology 1982;31(5):639-46.
-
1981: Sherry J H; O'Donnell J P; Colby H D
Conversion of spironolactone to an active metabolite in target tissues: formation of 7 alpha-thiospironolactone by microsomal preparations from guinea pig liver, adrenals, kidneys, and testes.
Life sciences 1981;29(26):2727-36.
-
1981: Colby H D; Johnson P B; Zulkoski J S; Pope M R; Miles P R
Comparative effects of cadmium, zinc, and lead in vitro on pulmonary, adrenal, and hepatic microsomal metabolism in the guinea pig.
Journal of toxicology and environmental health 1981;8(5-6):907-15.
-
1980: Colby H D; Marquess M L; Johnson P B; Pope M R
Effects of steroid hormones in vitro on adrenal xenobiotic metabolism in the guinea pig.
Biochemical pharmacology 1980;29(17):2373-7.
-
1980: Colby H D; Marquess M L; Johnson P B; Pope M R; Heaps P R
Comparative effects of mixed function oxidase inhibitors on adrenal and hepatic xenobiotic metabolism in the guinea pig.
Biochemical pharmacology 1980;29(6):951-3.
Sign-in to see more
