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Stewart Cole

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TOP 3
Jocelyne M Lew; Chunhong Mao; Brian D Robertson; Dirk Schnappinger; Maulik Shukla; Stewart T Cole; Stephen V Gordon; Dmitry Kuznetsov; Andrew Warren; Rebecca Will; Ioannis Xenarios; Bruno Sobral
Database resources for the tuberculosis community.
Swapna Uplekar; Stewart T Cole; Jacques Rougemont; Claudia Sala
High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis.
Benoit Lechartier; Ruben C Hartkoorn; Stewart T Cole
In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis.

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All Publications

2013: Jocelyne M Lew; Chunhong Mao; Brian D Robertson; Dirk Schnappinger; Maulik Shukla; Stewart T Cole; Stephen V Gordon; Dmitry Kuznetsov; Andrew Warren; Rebecca Will; Ioannis Xenarios; Bruno Sobral
Database resources for the tuberculosis community.
Tuberculosis (Edinburgh, Scotland) 2013;93(1):12-7.
2013: Swapna Uplekar; Stewart T Cole; Jacques Rougemont; Claudia Sala
High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis.
Nucleic acids research 2013;41(2):961-77.
2012: Benoit Lechartier; Ruben C Hartkoorn; Stewart T Cole
In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2012;56(11):5790-3.
2012: Ming Zhang; Neeraj Dhar; Ruben C Hartkoorn; Alfonso Mendoza-Losana; Claudia Sala; Stewart T Cole
Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis.
Antimicrobial agents and chemotherapy 2012;56(11):5782-9.
2012: Ruben C Hartkoorn; Sophie Magnet; Raju Mukherjee; João Neres; Florence Pojer; Claudia Sala; Swapna Uplekar; Karl-Heinz Altmann; Stefanie Boy-Röttger; Stewart T Cole
Towards a new tuberculosis drug: pyridomycin - nature's isoniazid.
EMBO molecular medicine 2012;4(10):1032-42.
2012: João Neres; Maria Rosalia Pasca; Florence Pojer; Randy J Read; Giovanna Riccardi; Giuseppe Zanoni; Stefanie Boy-Röttger; Silvia Buroni; Laurent R Chiarelli; Stewart T Cole; Edda De Rossi; Giulia Degiacomi; Neeraj Dhar; Paul J Dyson; Dale E Edmondson; Elizabeth Fullam; Anna Paola Lucarelli; Andrea Mattevi; John D McKinney; Elisabetta Molteni; Claudia Binda
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.
Science translational medicine 2012;4(150):150ra121.
2012: Stewart T Cole
Infectious diseases: Transporter targeted in tuberculosis.
Nature chemical biology 2012;8(4):326-7.
2012: Ruben C Hartkoorn; Jacques Rougemont; Claudia Sala; Swapna Uplekar; Philippe Busso; Stewart T Cole
Genome-wide definition of the SigF regulon in Mycobacterium tuberculosis.
Journal of bacteriology 2012;194(8):2001-9.
2012: Jeffrey M Chen; Stefanie Boy-Röttger; Roger S Buxton; Neeraj Dhar; Florence Pojer; Ida Rosenkrands; Nathan Sweeney; Stewart T Cole
EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.
Journal of bacteriology 2012;194(4):884-93.
2012: Claudia Trefzer; Henrieta Škovierová; Adela Bobovská; Silvia Buroni; Stewart T Cole; Vadim Makarov; Katarína Mikušová; Elisabetta Molteni; Simone Nenci; Maria R Pasca; Florence Pojer; Giovanna Riccardi; Kai Johnsson
Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.
Journal of the American Chemical Society 2012;134(2):912-5.
2012: Jeffrey M Chen; Stephen V Gordon; Swapna Uplekar; Stewart T Cole
A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains.
PloS one 2012;7(8):e43467.
2012: Elizabeth Fullam; T Alwyn Jones; Florence Pojer; Terese Bergfors; Stewart T Cole
Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme.
Open biology 2012;2(1):110026.
2012: Benjamin Blasco; Jeffrey M Chen; Ruben C Hartkoorn; Florence Pojer; Jacques Rougemont; Claudia Sala; Swapna Uplekar; Stewart T Cole
Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.
PLoS pathogens 2012;8(3):e1002621.
2011: Lucio Vera-Cabrera; Philippe Busso; Wendy G Escalante-Fuentes; Minerva Gomez-Flores; Jorge Ocampo-Candiani; Pushpendra Singh; Stewart T Cole
Case of diffuse lepromatous leprosy associated with "Mycobacterium lepromatosis".
Journal of clinical microbiology 2011;49(12):4366-8.
2011: Benjamin Blasco; Stewart T Cole; Giovanni Dietler; Matteo Dal Peraro; Livan Alonso-Sarduy; Marco Stenta; Florence Pojer
Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis.
Molecular microbiology 2011;82(1):251-64.
2011: Stewart T Cole; Giovanna Riccardi
New tuberculosis drugs on the horizon.
Current opinion in microbiology 2011;14(5):570-6.
2011: Swapna Uplekar; Véronique Friocourt; Beate Heym; Jacques Rougemont; Stewart T Cole
Comparative genomics of Esx genes from clinical isolates of Mycobacterium tuberculosis provides evidence for gene conversion and epitope variation.
Infection and immunity 2011;79(10):4042-9.
2011: Stewart T Cole
Microbiology. Pyrazinamide--old TB drug finds new target.
Science (New York, N.Y.) 2011;333(6049):1583-4.
2011: Pushpendra Singh; Philippe Busso; Alberto Paniz-Mondolfi; Nacarid Aranzazu; Marc Monot; Nadine Honore; Andrea de Faria Fernandes Belone; Marcos Virmond; Maria Esther Villarreal-Olaya; Carlos Rivas; Stewart T Cole
Molecular drug susceptibility testing and genotyping of Mycobacterium leprae strains from South America.
Antimicrobial agents and chemotherapy 2011;55(6):2971-3.
2011: Richard W Truman; Pushpendra Singh; Rahul Sharma; Philippe Busso; Jacques Rougemont; Alberto Paniz-Mondolfi; Adamandia Kapopoulou; Sylvain Brisse; David M Scollard; Thomas P Gillis; Stewart T Cole
Probable zoonotic leprosy in the southern United States.
The New England journal of medicine 2011;364(17):1626-33.
2011: Daria Bottai; Laleh Majlessi; Roxane Simeone; Wafa Frigui; Christine Laurent; Pascal Lenormand; Jeffrey Chen; Ida Rosenkrands; Michel Huerre; Claude Leclerc; Stewart T Cole; Roland Brosch
ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.
The Journal of infectious diseases 2011;203(8):1155-64.
2011: Pushpendra Singh; Stewart T Cole
Mycobacterium leprae: genes, pseudogenes and genetic diversity.
Future microbiology 2011;6(1):57-71.
2011: Adamandia Kapopoulou; Jocelyne M Lew; Stewart T Cole
The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes.
Tuberculosis (Edinburgh, Scotland) 2011;91(1):8-13.
2011: Jocelyne M Lew; Adamandia Kapopoulou; Louis M Jones; Stewart T Cole
TubercuList--10 years after.
Tuberculosis (Edinburgh, Scotland) 2011;91(1):1-7.
2010: Sophie Magnet; Ruben C Hartkoorn; Rita Székely; János Pató; James A Triccas; Patricia Schneider; Csaba Szántai-Kis; László Őrfi; Marc Chambon; Damiano Banfi; Manuel Bueno; Gerardo Turcatti; György Kéri; Stewart T Cole
Leads for antitubercular compounds from kinase inhibitor library screens.
Tuberculosis (Edinburgh, Scotland) 2010;90(6):354-60.
2010: Claudia Trefzer; Monica Rengifo-Gonzalez; Marlon J Hinner; Patricia Schneider; Vadim Makarov; Stewart T Cole; Kai Johnsson
Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis.
Journal of the American Chemical Society 2010;132(39):13663-5.
2010: Ruben C Hartkoorn; Claudia Sala; Sophie J Magnet; Jeffrey M Chen; Florence Pojer; Stewart T Cole
Sigma factor F does not prevent rifampin inhibition of RNA polymerase or cause rifampin tolerance in Mycobacterium tuberculosis.
Journal of bacteriology 2010;192(20):5472-9.
2010: Claudia Sala; Neeraj Dhar; Ruben C Hartkoorn; Ming Zhang; Young Hwan Ha; Patricia Schneider; Stewart T Cole
Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2010;54(10):4150-8.
2010: V Salzman; S Mondino; C Sala; Stewart T Cole; G Gago; Hugo Gramajo
Transcriptional regulation of lipid homeostasis in mycobacteria.
Molecular microbiology 2010;78(1):64-77.
2010: Giulia Manina; Marco Bellinzoni; Maria Rosalia Pasca; João Neres; Anna Milano; Ana Luisa De Jesus Lopes Ribeiro; Silvia Buroni; Henrieta Skovierová; Petronela Dianišková; Katarína Mikušová; Jozef Marák; Vadim Makarov; David Giganti; Ahmed Haouz; Anna Paola Lucarelli; Giulia Degiacomi; Aurora Piazza; Laurent R Chiarelli; Edda De Rossi; Elena Salina; Stewart T Cole; Pedro Alzari; Giovanna Riccardi
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance.
Molecular microbiology 2010;77(5):1172-85.
2010: Laurent Dacheux; Nicolas Berthet; Gabriel Dissard; Edward C Holmes; Olivier Delmas; Florence Larrous; Ghislaine Guigon; Philip Dickinson; Ousmane Faye; Amadou A Sall; Iain G Old; Katherine Kong; Giulia C Kennedy; Jean-Claude Manuguerra; Stewart T Cole; Valérie Caro; Antoine Gessain; Hervé Bourhy
Application of broad-spectrum resequencing microarray for genotyping rhabdoviruses.
Journal of virology 2010;84(18):9557-74.
2010: Andreas Massouras; Korneel Hens; Carine Gubelmann; Swapna Uplekar; Frederik Decouttere; Jacques Rougemont; Stewart T Cole; Bart Deplancke
Primer-initiated sequence synthesis to detect and assemble structural variants.
Nature methods 2010;7(7):485-6.
2010: Simone Bonazzi; Damien Barbaras; Luc Patiny; Rosario Scopelliti; Patricia Schneider; Stewart T Cole; Marcel Kaiser; Reto Brun; Karl Gademann
Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation.
Bioorganic & medicinal chemistry 2010;18(4):1464-76.
2010: Nicolas Berthet; Alexis Deletoile; Virginie Passet; Giulia C Kennedy; Jean-Claude Manuguerra; Stewart T Cole; Sylvain Brisse
Reconstructed ancestral sequences improve pathogen identification using resequencing DNA microarrays.
PloS one 2010;5(12):e15243.
2010: India Leclercq; Nicolas Berthet; Christophe Batéjat; Claudine Rousseaux; Philip Dickinson; Iain G Old; Katherine Kong; Giulia C Kennedy; Stewart T Cole; Jean-Claude Manuguerra
Use of consensus sequences for the design of high density resequencing microarrays: the influenza virus paradigm.
BMC genomics 2010;11():586.
2009: Carmen Buchrieser; Stewart T Cole
From functional genomics to systems (micro)biology.
Current opinion in microbiology 2009;12(5):528-30.
2009: Luke Alvey; Soizic Prado; Brigitte Saint-Joanis; Sylvie Michel; Michel Koch; Stewart T Cole; François Tillequin; Yves L Janin
Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity.
European journal of medicinal chemistry 2009;44(6):2497-505.
2009: Claudia Sala; David C Grainger; Stewart T Cole
Dissecting regulatory networks in host-pathogen interaction using chIP-on-chip technology.
Cell host & microbe 2009;5(5):430-7.
2009: Claudia Sala; Ahmed Haouz; Frederick A Saul; Isabelle Miras; Ida Rosenkrands; Pedro Alzari; Stewart T Cole
Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis.
Molecular microbiology 2009;71(5):1102-16.
2008: Kirsty J McLean; Paul Carroll; D Geraint Lewis; Adrian J Dunford; Harriet E Seward; Rajasekhar Neeli; Myles R Cheesman; Laurent Marsollier; Philip Douglas; W Ewen Smith; Ida Rosenkrands; Stewart T Cole; David Leys; Tanya Parish; Andrew W Munro
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
The Journal of biological chemistry 2008;283(48):33406-16.
2008: Luke Alvey; Soizic Prado; Valérie Huteau; Brigitte Saint-Joanis; Sylvie Michel; Michel Koch; Stewart T Cole; François Tillequin; Yves L Janin
A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial.
Bioorganic & medicinal chemistry 2008;16(17):8264-72.
2008: Petra Tafelmeyer; Christine Laurent; Pascal Lenormand; Jean-Claude Rousselle; Laurent Marsollier; Gilles Reysset; Runxuan Zhang; Albert Sickmann; Timothy P Stinear; Abdelkader Namane; Stewart T Cole
Comprehensive proteome analysis of Mycobacterium ulcerans and quantitative comparison of mycolactone biosynthesis.
Proteomics 2008;8(15):3124-38.
2008: Marc Monot; Nadine Honoré; Charlotte Balière; Baohong Ji; Samba Sow; Patrick J Brennan; Stewart T Cole
Are variable-number tandem repeats appropriate for genotyping Mycobacterium leprae?
Journal of clinical microbiology 2008;46(7):2291-7.
2008: Rita Székely; Frigyes Wáczek; István Szabadkai; Gábor Németh; Bálint Hegymegi-Barakonyi; Dániel Eros; Bálint Szokol; János Pató; Doris Hafenbradl; Jacqueline Satchell; Brigitte Saint-Joanis; Stewart T Cole; László Őrfi; Bert M Klebl; György Kéri
A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling.
Immunology letters 2008;116(2):225-31.
2008: Wafa Frigui; Daria Bottai; Laleh Majlessi; Marc Monot; Emmanuelle Josselin; Priscille Brodin; Thierry Garnier; Brigitte Gicquel; Carlos Martin; CLAUDE LECLERC; Stewart T Cole; Roland Brosch
Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP.
PLoS pathogens 2008;4(2):e33.
2008: Marie-Laure Chesne-seck; Nathalie Barilone; Frédéric Boudou; Jesús Gonzalo Asensio; Pappachan Kolattukudy; Carlos Martín; Stewart T Cole; Brigitte Gicquel; Deshmukh N Gopaul; Mary Jackson
A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra.
Journal of bacteriology 2008;190(4):1329-34.
2008: Nicolas Berthet; Philip Dickinson; Ingrid Filliol; Anita K Reinhardt; Christophe Batejat; Tatiana Vallaeys; Katherine A Kong; Christopher Davies; Walter Lee; Shenglan Zhang; Yaron Turpaz; Beate Heym; Gilberte Coralie; Laurent Dacheux; Ana Maria Burguière; Hervé Bourhy; Iain G Old; Jean-Claude Manuguerra; Stewart T Cole; Giulia C Kennedy
Massively parallel pathogen identification using high-density microarrays.
Microbial biotechnology 2008;1(1):79-86.
2008: Nicolas Berthet; Anita K Reinhardt; India Leclercq; Sven van Ooyen; Christophe Batéjat; Philip Dickinson; Rayna Stamboliyska; Iain G Old; Katherine A Kong; Laurent Dacheux; Hervé Bourhy; Giulia C Kennedy; Christian Korfhage; Stewart T Cole; Jean-Claude Manuguerra
Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR.
BMC molecular biology 2008;9():77.
2008: Annemarie Wehenkel; Marco Bellinzoni; Martin Graña; Rosario Duran; Andrea Villarino; Pablo Fernandez; Gwénaëlle Andre-Leroux; Patrick England; Howard Takiff; Carlos Cerveñansky; Stewart T Cole; Pedro Alzari
Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential.
Biochimica et biophysica acta 2008;1784(1):193-202.
2007: Martin Graña; Ahmed Haouz; Alejandro Buschiazzo; Isabelle Miras; Annemarie Wehenkel; Vincent Bondet; William Shepard; Francis Schaeffer; Stewart T Cole; Pedro Alzari
The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria.
Protein science : a publication of the Protein Society 2007;16(9):1896-904.
2007: Marien I de Jonge; Gérard Pehau-Arnaudet; Marjan M Fretz; Felix Romain; Daria Bottai; Priscille Brodin; Nadine Honoré; Gilles Marchal; Wim Jiskoot; Patrick England; Stewart T Cole; Roland Brosch
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity.
Journal of bacteriology 2007;189(16):6028-34.
2007: Emmanuelle Coutanceau; Jeremie Decalf; Angelo Martino; Aurélie Babon; Nathalie Winter; Stewart T Cole; Matthew L Albert; Caroline Demangel
Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone.
The Journal of experimental medicine 2007;204(6):1395-403.
2007: Laurent Marsollier; Priscille Brodin; Mary Jackson; Jana Korduláková; Petra Tafelmeyer; Etienne Carbonnelle; Jacques Aubry; Geneviève Milon; Pierre Legras; Jean-Paul Saint André; Céline Leroy; Jane Cottin; Marie Laure Joly Guillou; Gilles Reysset; Stewart T Cole
Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.
PLoS pathogens 2007;3(5):e62.
2007: Roland Brosch; Stephen Gordon; Thierry Garnier; Karin Eiglmeier; Wafa Frigui; Philippe Valenti; Sandrine Dos Santos; Stéphanie Duthoy; Céline Lacroix; Carmen Garcia-Pelayo; Jacqueline Inwald; Paul Golby; Javier Nuñez Garcia; R Glyn Hewinson; Marcel A Behr; Michael A Quail; Carol Churcher; Bart Barrell; Julian Parkhill; Stewart T Cole
Genome plasticity of BCG and impact on vaccine efficacy.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5596-601.
2007: Soizic Prado; Yves L Janin; Brigitte Saint-Joanis; Priscille Brodin; Sylvie Michel; Michel Koch; Stewart T Cole; François Tillequin; Pierre-Etienne Bost
Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues.
Bioorganic & medicinal chemistry 2007;15(5):2177-86.
2007: William Shepard; Ahmed Haouz; Martin Graña; Alejandro Buschiazzo; Jean-Michel Betton; Stewart T Cole; Pedro Alzari
The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria.
Journal of bacteriology 2007;189(5):1899-904.
2007: Laurent Marsollier; Estelle Deniaux; Priscille Brodin; Agnès Marot; Christelle Mbondji Wondje; Jean-Paul Saint-André; Annick Chauty; Christian Johnson; Fredj Tekaia; Edouard Yeramian; Pierre Legras; Bernard Carbonnelle; Gilles Reysset; Sara Eyangoh; Geneviève Milon; Stewart T Cole; Jacques Aubry
Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva.
PLoS medicine 2007;4(2):e64.
2007: Timothy P Stinear; Torsten Seemann; Sacha Pidot; Wafa Frigui; Gilles Reysset; Thierry Garnier; Guillaume Meurice; David Simon; Christiane Bouchier; Laurence Ma; Magali Tichit; Jessica L Porter; Janine Ryan; Paul Johnson; John K Davies; Grant A Jenkin; Pamela L C Small; Louis M Jones; Fredj Tekaia; Françoise Laval; Mamadou Daffé; Julian Parkhill; Stewart T Cole
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.
Genome research 2007;17(2):192-200.
2007: Laurent Marsollier; Jean-Paul Saint André; Wafa Frigui; Gilles Reysset; Geneviève Milon; Bernard Carbonnelle; Jacques Aubry; Stewart T Cole
Early trafficking events of Mycobacterium ulcerans within Naucoris cimicoides.
Cellular microbiology 2007;9(2):347-55.
2006: Pablo Fernandez; Brigitte Saint-Joanis; Nathalie Barilone; Mary Jackson; Brigitte Gicquel; Stewart T Cole; Pedro Alzari
The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth.
Journal of bacteriology 2006;188(22):7778-84.
2006: Brigitte Saint-Joanis; Caroline Demangel; Mary Jackson; Priscille Brodin; Laurent Marsollier; Helena Boshoff; Stewart T Cole
Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence.
Journal of bacteriology 2006;188(18):6669-79.
2006: Soizic Prado; Hervé Ledeit; Sylvie Michel; Michel Koch; Jacques-Christian Darbord; Stewart T Cole; François Tillequin; Priscille Brodin
Benzofuro[3,2-f][1]benzopyrans: a new class of antitubercular agents.
Bioorganic & medicinal chemistry 2006;14(15):5423-8.
2006: Romulo Aráoz; Nadine Honoré; Sayera Banu; Caroline Demangel; Yacouba Cissoko; Charles Arama; Mohammad Khaja Mafij Uddin; S K Abdul Hadi; Marc Monot; Sang-Nae Cho; Baohong Ji; Patrick J Brennan; Samba Sow; Stewart T Cole
Towards an immunodiagnostic test for leprosy.
Microbes and infection / Institut Pasteur 2006;8(8):2270-6.
2006: Emmanuelle Coutanceau; Pierre Legras; Laurent Marsollier; Gilles Reysset; Stewart T Cole; Caroline Demangel
Immunogenicity of Mycobacterium ulcerans Hsp65 and protective efficacy of a Mycobacterium leprae Hsp65-based DNA vaccine against Buruli ulcer.
Microbes and infection / Institut Pasteur 2006;8(8):2075-81.
2006: Laleh Majlessi; Marcela Simsova; Zdenka Jarvis; Priscille Brodin; Marion Rojas; Cecile Bauche; Clémence Nouzé; Daniel Ladant; Stewart T Cole; Peter Sebo; CLAUDE LECLERC
An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis.
Infection and immunity 2006;74(4):2128-37.
2006: Romulo Aráoz; Nadine Honoré; Sungae Cho; Jong-Pill Kim; Sang-Nae Cho; Marc Monot; Caroline Demangel; Patrick J Brennan; Stewart T Cole
Antigen discovery: a postgenomic approach to leprosy diagnosis.
Infection and immunity 2006;74(1):175-82.
2006: Priscille Brodin; Laleh Majlessi; Laurent Marsollier; Marien I de Jonge; Daria Bottai; Caroline Demangel; Jason Hinds; Olivier Neyrolles; Philip Butcher; CLAUDE LECLERC; Stewart T Cole; Roland Brosch
Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence.
Infection and immunity 2006;74(1):88-98.
2005: John S Spencer; Hazel M Dockrell; Hee Jin Kim; Maria Angela M Marques; Diana L Williams; Marcia V S B Martins; Marcio L F Martins; Monica C B S Lima; Euzenir N Sarno; Geraldo Pereira; Haroldo J Matos; Leila S Fonseca; Elizabeth P Sampaio; Tom H M Ottenhoff; Annemieke Geluk; Sang-Nae Cho; neil stoker; Stewart T Cole; Patrick J Brennan; Maria Cristina Vidal Pessolani
Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):7930-8.
2005: Priscille Brodin; Marien I de Jonge; Laleh Majlessi; CLAUDE LECLERC; Michael Nilges; Stewart T Cole; Roland Brosch
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.
The Journal of biological chemistry 2005;280(40):33953-9.
2005: Rosario Durán; Andrea Villarino; Marco Bellinzoni; Annemarie Wehenkel; Pablo Fernandez; Brigitte Boitel; Stewart T Cole; Pedro Alzari; Carlos Cerveñansky
Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases.
Biochemical and biophysical research communications 2005;333(3):858-67.
2005: Marien I de Jonge; Roland Brosch; Priscille Brodin; Caroline Demangel; Stewart T Cole
Tuberculosis: from genome to vaccine.
Expert review of vaccines 2005;4(4):541-51.
2005: Emmanuelle Coutanceau; Laurent Marsollier; Roland Brosch; Emmanuelle Perret; Pierre L Goossens; Myriam Tanguy; Stewart T Cole; Pamela L C Small; Caroline Demangel
Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin.
Cellular microbiology 2005;7(8):1187-96.
2005: Andrea Villarino; R Duran; Annemarie Wehenkel; Pablo Fernandez; Patrick England; Priscille Brodin; Stewart T Cole; Ursula Zimny-Arndt; Peter Jungblut; Carlos Cerveñansky; Pedro Alzari
Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions.
Journal of molecular biology 2005;350(5):953-63.
2005: Beatriz G Guimarães; Hélène Souchon; Nadine Honoré; Brigitte Saint-Joanis; Roland Brosch; William Shepard; Stewart T Cole; Pedro Alzari
Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress.
The Journal of biological chemistry 2005;280(27):25735-42.
2005: Laurent Marsollier; Jacques Aubry; Emmanuelle Coutanceau; Jean-Paul Saint André; Pamela L C Small; Geneviève Milon; Pierre Legras; Stéphanie Guadagnini; Bernard Carbonnelle; Stewart T Cole
Colonization of the salivary glands of Naucoris cimicoides by Mycobacterium ulcerans requires host plasmatocytes and a macrolide toxin, mycolactone.
Cellular microbiology 2005;7(7):935-43.
2005: Marc Monot; Nadine Honoré; Thierry Garnier; Romulo Araoz; Jean-Yves Coppée; Céline Lacroix; Samba Sow; John S Spencer; Richard W Truman; Diana L Williams; Robert Gelber; Marcos Virmond; Béatrice Flageul; Sang-Nae Cho; Baohong Ji; Alberto Paniz-Mondolfi; Jacinto Convit; Saroj Young; Paul E Fine; Voahangy Rasolofo; Patrick J Brennan; Stewart T Cole
On the origin of leprosy.
Science (New York, N.Y.) 2005;308(5724):1040-2.
2005: Caroline Demangel; Thierry Garnier; Ida Rosenkrands; Stewart T Cole
Differential effects of prior exposure to environmental mycobacteria on vaccination with Mycobacterium bovis BCG or a recombinant BCG strain expressing RD1 antigens.
Infection and immunity 2005;73(4):2190-6.
2005: Laleh Majlessi; Priscille Brodin; Roland Brosch; Marion Rojas; Huot Khun; Michel Huerre; Stewart T Cole; CLAUDE LECLERC
Influence of ESAT-6 secretion system 1 (RD1) of Mycobacterium tuberculosis on the interaction between mycobacteria and the host immune system.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3570-9.
2005: Timothy P Stinear; Melinda J Pryor; Jessica L Porter; Stewart T Cole
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.
Microbiology (Reading, England) 2005;151(Pt 3):683-92.
2005: Timothy P Stinear; Hui Hong; Wafa Frigui; Melinda J Pryor; Roland Brosch; Thierry Garnier; Peter F Leadlay; Stewart T Cole
Common evolutionary origin for the unstable virulence plasmid pMUM found in geographically diverse strains of Mycobacterium ulcerans.
Journal of bacteriology 2005;187(5):1668-76.
2005: Stewart T Cole; Pedro Alzari
Microbiology. TB--a new target, a new drug.
Science (New York, N.Y.) 2005;307(5707):214-5.
2004: Priscille Brodin; Ida Rosenkrands; Peter Andersen; Stewart T Cole; Roland Brosch
ESAT-6 proteins: protective antigens and virulence factors?
Trends in microbiology 2004;12(11):500-8.
2004: Laurent Marsollier; Tchibozo Sévérin; Jacques Aubry; Richard W Merritt; Jean-Paul Saint-André; Pierre Legras; Anne-Lise Manceau; Annick Chauty; Bernard Carbonnelle; Stewart T Cole
Aquatic snails, passive hosts of Mycobacterium ulcerans.
Applied and environmental microbiology 2004;70(10):6296-8.
2004: Priscille Brodin; Laleh Majlessi; Roland Brosch; Debbie Smith; Gregory Bancroft; Simon Clark; Ann Williams; CLAUDE LECLERC; Stewart T Cole
Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens.
The Journal of infectious diseases 2004;190(1):115-22.
2004: John S Spencer; Hee Jin Kim; Angela M Marques; Mercedes Gonzalez-Juarerro; Monica C B S Lima; Varalakshmi D Vissa; Richard W Truman; Maria Laura Gennaro; Sang-Nae Cho; Stewart T Cole; Patrick J Brennan
Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10.
Infection and immunity 2004;72(6):3161-70.
2004: Caroline Demangel; Priscille Brodin; Paul J Cockle; Roland Brosch; Laleh Majlessi; CLAUDE LECLERC; Stewart T Cole
Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.
Infection and immunity 2004;72(4):2170-6.
2004: Timothy P Stinear; Armand Mve-Obiang; Pamela L C Small; Wafa Frigui; Melinda J Pryor; Roland Brosch; Grant A Jenkin; Paul Johnson; John K Davies; Richard E Lee; Sarojini Adusumilli; Thierry Garnier; Stephen F Haydock; Peter F Leadlay; Stewart T Cole
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1345-9.
2004: Magali Marmiesse; Priscille Brodin; Carmen Buchrieser; Christina Gutierrez; Nathalie Simoes; Véronique Vincent; Philippe Glaser; Stewart T Cole; Roland Brosch
Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex.
Microbiology (Reading, England) 2004;150(Pt 2):483-96.
2004: Sayera Banu; Stephen Gordon; Si Palmer; M Rizaul Islam; Shakeel Ahmed; Khorshed Alam; Stewart T Cole; Roland Brosch
Genotypic analysis of Mycobacterium tuberculosis in Bangladesh and prevalence of the Beijing strain.
Journal of clinical microbiology 2004;42(2):674-82.
2004: Caroline Demangel; Roland Brosch; Magali Marmiesse; Stewart T Cole
[Use of the mycobacteria genome to develop new vaccines and therapeutic targets].
Médecine tropicale : revue du Corps de santé colonial 2004;64(3):221-3.
2003: Hui Hong; Paul J Gates; James Staunton; Timothy P Stinear; Stewart T Cole; Peter F Leadlay; Jonathan B Spencer
Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans.
Chemical communications (Cambridge, England) 2003;(22):2822-3.
2003: Brigitte Boitel; Miguel Ortiz-Lombardía; Rosario Durán; Fréderique Pompeo; Stewart T Cole; Carlos Cerveñansky; Pedro Alzari
PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis.
Molecular microbiology 2003;49(6):1493-508.
2003: Thierry Garnier; Karin Eiglmeier; Jean-Christophe Camus; Nadine Medina; Huma Mansoor; Melinda J Pryor; Stephanie Duthoy; Sophie Grondin; Céline Lacroix; Christel Monsempe; Sylvie Simon; Barbara Harris; Rebecca Atkin; Jon Doggett; Rebecca Mayes; Lisa Keating; Paul R Wheeler; Julian Parkhill; Bart Barrell; Stewart T Cole; Stephen Gordon; R Glyn Hewinson
The complete genome sequence of Mycobacterium bovis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7877-82.
2003: Alexander S Pym; Priscille Brodin; Laleh Majlessi; Roland Brosch; Caroline Demangel; Ann Williams; Karen E Griffiths; Gilles Marchal; CLAUDE LECLERC; Stewart T Cole
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.
Nature medicine 2003;9(5):533-9.
2003: Laurent Marsollier; Nadine Honoré; Pierre Legras; Anne-Lise Manceau; Henri Kouakou; Bernard Carbonnelle; Stewart T Cole
Isolation of three Mycobacterium ulcerans strains resistant to rifampin after experimental chemotherapy of mice.
Antimicrobial agents and chemotherapy 2003;47(4):1228-32.
2002: Alexander S Pym; Priscille Brodin; Roland Brosch; Michel Huerre; Stewart T Cole
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti.
Molecular microbiology 2002;46(3):709-17.
2002: Jean-Christophe Camus; Melinda J Pryor; Claudine Médigue; Stewart T Cole
Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv.
Microbiology (Reading, England) 2002;148(Pt 10):2967-73.
2002: Stewart T Cole
Comparative and functional genomics of the Mycobacterium tuberculosis complex.
Microbiology (Reading, England) 2002;148(Pt 10):2919-28.
2002: Priscille Brodin; Karin Eiglmeier; Magali Marmiesse; Alain Billault; Thierry Garnier; Stefan Niemann; Stewart T Cole; Roland Brosch
Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant.
Infection and immunity 2002;70(10):5568-78.
2002: Alexander S Pym; Brigitte Saint-Joanis; Stewart T Cole
Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans.
Infection and immunity 2002;70(9):4955-60.
2002: Sayera Banu; Nadine Honoré; Brigitte Saint-Joanis; Dana J Philpott; Marie-Christine Prévost; Stewart T Cole
Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens?
Molecular microbiology 2002;44(1):9-19.
2002: Roland Brosch; Stephen Gordon; Magali Marmiesse; Priscille Brodin; Carmen Buchrieser; Karin Eiglmeier; Thierry Garnier; C Gutierrez; Glyn Hewinson; Kristin Kremer; L M Parsons; Alexander S Pym; S Samper; Dick Van Soolingen; Stewart T Cole
A new evolutionary scenario for the Mycobacterium tuberculosis complex.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3684-9.
2002: Pilar Domenech; Alexander S Pym; M Cellier; C E Barry; Stewart T Cole
Inactivation of the Mycobacterium tuberculosis Nramp orthologue (mntH) does not affect virulence in a mouse model of tuberculosis.
FEMS microbiology letters 2002;207(1):81-6.
2002: Stephen Gordon; Roland Brosch; Karin Eiglmeier; Thierry Garnier; R Glyn Hewinson; Stewart T Cole
Royal Society of Tropical Medicine and Hygiene Meeting at Manson House, London, 18th January 2001. Pathogen genomes and human health. Mycobacterial genomics.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2002;96(1):1-6.
2001: Louis Jones; Ivan Moszer; Stewart T Cole
Leproma: a Mycobacterium leprae genome browser.
Leprosy review 2001;72(4):470-7.
2001: Karin Eiglmeier; Sylvie Simon; Thierry Garnier; Stewart T Cole
The integrated genome map of Mycobacterium leprae.
Leprosy review 2001;72(4):462-9.
2001: Stewart T Cole; Philip Supply; Nadine Honoré
Repetitive sequences in Mycobacterium leprae and their impact on genome plasticity.
Leprosy review 2001;72(4):449-61.
2001: Nadine Honoré; P W Roche; Jacques H Grosset; Stewart T Cole
A method for rapid detection of rifampicin-resistant isolates of Mycobacterium leprae.
Leprosy review 2001;72(4):441-8.
2001: Karin Eiglmeier; Julian Parkhill; Nadine Honoré; Thierry Garnier; Fredj Tekaia; A Telenti; P Klatser; Keith D James; Nicholas R Thomson; Paul R Wheeler; Carol Churcher; D Harris; Karen Mungall; Bart Barrell; Stewart T Cole
The decaying genome of Mycobacterium leprae.
Leprosy review 2001;72(4):387-98.
2001: Roland Brosch; Alexander S Pym; Stephen Gordon; Stewart T Cole
The evolution of mycobacterial pathogenicity: clues from comparative genomics.
Trends in microbiology 2001;9(9):452-8.
2001: Pilar Domenech; Nadine Honoré; B Heym; Stewart T Cole
Role of OxyS of Mycobacterium tuberculosis in oxidative stress: overexpression confers increased sensitivity to organic hydroperoxides.
Microbes and infection / Institut Pasteur 2001;3(9):713-21.
2001: Matteo Sofia; Mauro Maniscalco; Nadine Honoré; A Molino; Mauro Mormile; B Heym; Stewart T Cole
Familial outbreak of disseminated multidrug-resistant tuberculosis and meningitis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2001;5(6):551-8.
2001: Alexander S Pym; Pilar Domenech; Nadine Honoré; J Song; Vojo Deretic; Stewart T Cole
Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis.
Molecular microbiology 2001;40(4):879-89.
2001: Pilar Domenech; C E Barry; Stewart T Cole
Mycobacterium tuberculosis in the post-genomic age.
Current opinion in microbiology 2001;4(1):28-34.
2001: Stephen Gordon; Karin Eiglmeier; Thierry Garnier; Roland Brosch; Julian Parkhill; Bart Barrell; Stewart T Cole; R Glyn Hewinson
Genomics of Mycobacterium bovis.
Tuberculosis (Edinburgh, Scotland) 2001;81(1-2):157-63.
2000: Stewart T Cole; N Honore; Karin Eiglmeier
Preliminary analysis of the genome sequence of Mycobacterium leprae.
Leprosy review 2000;71 Suppl():S162-4; discussion S164-7.
2000: Alberto Alape-Girón; Marietta Flores-Díaz; Isabelle Guillouard; Claire E Naylor; Richard Titball; Alexandra Rucavado; Bruno Lomonte; Ajit K Basak; José María Gutiérrez; Stewart T Cole; Monica Thelestam
Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene.
European journal of biochemistry / FEBS 2000;267(16):5191-7.
2000: Roland Brosch; Stephen Gordon; Carmen Buchrieser; Alexander S Pym; Thierry Garnier; Stewart T Cole
Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur.
Yeast (Chichester, England) 2000;17(2):111-23.
2000: Roland Brosch; Stephen Gordon; Alexander S Pym; Karin Eiglmeier; Thierry Garnier; Stewart T Cole
Comparative genomics of the mycobacteria.
International journal of medical microbiology : IJMM 2000;290(2):143-52.
2000: Roland Brosch; Stephen Gordon; Karin Eiglmeier; Thierry Garnier; Stewart T Cole
Comparative genomics of the leprosy and tubercle bacilli.
Research in microbiology 2000;151(2):135-42.
2000: Sayera Banu; Kaori Ohtani; Harumi Yaguchi; T Swe; Stewart T Cole; Hideo Hayashi; Tohru Shimizu
Identification of novel VirR/VirS-regulated genes in Clostridium perfringens.
Molecular microbiology 2000;35(4):854-64.
1999: Roland Brosch; W J Philipp; Evangelos Stavropoulos; M Joseph Colston; Stewart T Cole; Stephen Gordon
Genomic analysis reveals variation between Mycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain.
Infection and immunity 1999;67(11):5768-74.
1999: Stephen Gordon; Roland Brosch; Alain Billault; Thierry Garnier; Karin Eiglmeier; Stewart T Cole
Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays.
Molecular microbiology 1999;32(3):643-55.
1999: Stephen Gordon; B Heym; Julian Parkhill; Bart Barrell; Stewart T Cole
New insertion sequences and a novel repeated sequence in the genome of Mycobacterium tuberculosis H37Rv.
Microbiology (Reading, England) 1999;145 ( Pt 4)():881-92.
1999: Alexander S Pym; Stewart T Cole
Post DOTS, post genomics: the next century of tuberculosis control.
Lancet 1999;353(9157):1004-5.
1999: Brigitte Saint-Joanis; Hélène Souchon; Martin Wilming; Kai Johnsson; Pedro Alzari; Stewart T Cole
Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis.
The Biochemical journal 1999;338 ( Pt 3)():753-60.
1999: Fredj Tekaia; Stephen Gordon; Thierry Garnier; Roland Brosch; Bart Barrell; Stewart T Cole
Analysis of the proteome of Mycobacterium tuberculosis in silico.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;79(6):329-42.
1999: B Heym; Brigitte Saint-Joanis; Stewart T Cole
The molecular basis of isoniazid resistance in Mycobacterium tuberculosis.
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;79(4):267-71.
1998: F S Silbaq; Sang-Nae Cho; Stewart T Cole; Patrick J Brennan
Characterization of a 34-kilodalton protein of Mycobacterium leprae that is isologous to the immunodominant 34-kilodalton antigen of Mycobacterium paratuberculosis.
Infection and immunity 1998;66(11):5576-9.
1998: Stewart T Cole
Comparative mycobacterial genomics.
Current opinion in microbiology 1998;1(5):567-71.
1998: Roland Brosch; Stephen Gordon; Alain Billault; Thierry Garnier; Karin Eiglmeier; C Soravito; Bart Barrell; Stewart T Cole
Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics.
Infection and immunity 1998;66(5):2221-9.
1998: WJ Philipp; D C Schwartz; Amalio Telenti; Stewart T Cole
Mycobacterial genome structure.
Electrophoresis 1998;19(4):573-6.
1998: Amalio Telenti; Nadine Honoré; Stewart T Cole
Detection of mutations in mycobacteria by PCR-SSCP (single-strand conformation polymorphism).
Methods in molecular biology (Clifton, N.J.) 1998;101():423-30.
1998: S Bergh; Stewart T Cole
Using MycDB on the World-Wide Web.
Methods in molecular biology (Clifton, N.J.) 1998;101():109-18.
1998: WJ Philipp; S Gordon; Amalio Telenti; Stewart T Cole
Pulsed field gel electrophoresis for mycobacteria.
Methods in molecular biology (Clifton, N.J.) 1998;101():51-63.
1997: Isabelle Guillouard; Pedro Alzari; B Saliou; Stewart T Cole
The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition.
Molecular microbiology 1997;26(5):867-76.
1997: Bruno Dupuy; Georges DAUBE; Michel R Popoff; Stewart T Cole
Clostridium perfringens urease genes are plasmid borne.
Infection and immunity 1997;65(6):2313-20.
1997: Karin Eiglmeier; Hafida Fsihi; B Heym; Stewart T Cole
On the catalase-peroxidase gene, katG, of Mycobacterium leprae and the implications for treatment of leprosy with isoniazid.
FEMS microbiology letters 1997;149(2):273-8.
1997: B Heym; Evangelos Stavropoulos; Nadine Honoré; Pilar Domenech; Brigitte Saint-Joanis; T M Wilson; D M Collins; M Joseph Colston; Stewart T Cole
Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.
Infection and immunity 1997;65(4):1395-401.
1997: Amalio Telenti; Nadine Honoré; C Bernasconi; J March; A Ortega; B Heym; H E Takiff; Stewart T Cole
Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level.
Journal of clinical microbiology 1997;35(3):719-23.
1996: Stewart T Cole
Why sequence the genome of Mycobacterium tuberculosis?
Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1996;77(6):486-90.
1996: H Fsihi; Edda De Rossi; L Salazar; Rita Maria Cantoni; M Labò; Giovanna Riccardi; H E Takiff; Karin Eiglmeier; S Bergh; Stewart T Cole
Gene arrangement and organization in a approximately 76 kb fragment encompassing the oriC region of the chromosome of Mycobacterium leprae.
Microbiology (Reading, England) 1996;142 ( Pt 11)():3147-61.
1996: W J Philipp; S Nair; G Guglielmi; Micheline Lagranderie; Brigitte Gicquel; Stewart T Cole
Physical mapping of Mycobacterium bovis BCG pasteur reveals differences from the genome map of Mycobacterium tuberculosis H37Rv and from M. bovis.
Microbiology (Reading, England) 1996;142 ( Pt 11)():3135-45.
1996: S Katayama; B Dupuy; Georges DAUBE; Bernard China; Stewart T Cole
Genome mapping of Clostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne.
Molecular & general genetics : MGG 1996;251(6):720-6.
1996: I Guillouard; Thierry Garnier; Stewart T Cole
Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens.
Infection and immunity 1996;64(7):2440-4.
1996: H Fsihi; Véronique Vincent; Stewart T Cole
Homing events in the gyrA gene of some mycobacteria.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(8):3410-5.
1996: W J Philipp; S Poulet; Karin Eiglmeier; L Pascopella; V Balasubramanian; B Heym; S Bergh; Barry R Bloom; William R. Jacobs Jr.; Stewart T Cole
An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3132-7.
1996: L Salazar; H Fsihi; Edda De Rossi; Giovanna Riccardi; C Rios; Stewart T Cole; H E Takiff
Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis.
Molecular microbiology 1996;20(2):283-93.
1996: B Heym; W Philipp; Stewart T Cole
Mechanisms of drug resistance in Mycobacterium tuberculosis.
Current topics in microbiology and immunology 1996;215():49-69.
1996: Stewart T Cole
Rifamycin resistance in mycobacteria.
Research in microbiology 1996;147(1-2):48-52.
1995: W J Philipp; Stewart T Cole
Local comparison of the genomes of Mycobacterium tuberculosis and Mycobacterium leprae using the polymerase chain reaction.
FEMS microbiology letters 1995;132(3):263-9.
1995: S Katayama; B Dupuy; Thierry Garnier; Stewart T Cole
Rapid expansion of the physical and genetic map of the chromosome of Clostridium perfringens CPN50.
Journal of bacteriology 1995;177(19):5680-5.
1995: Vojo Deretic; W Philipp; Subramanian Dhandayuthapani; MH Mudd; R Curcic; T Garbe; B Heym; Laura Via; Stewart T Cole
Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid.
Molecular microbiology 1995;17(5):889-900.
1995: Stewart T Cole; A Telenti
Drug resistance in Mycobacterium tuberculosis.
The European respiratory journal. Supplement 1995;20():701s-713s.
1995: H Fsihi; Stewart T Cole
The Mycobacterium leprae genome: systematic sequence analysis identifies key catabolic enzymes, ATP-dependent transport systems and a novel polA locus associated with genomic variability.
Molecular microbiology 1995;16(5):909-19.
1995: Nadine Honoré; G Marchal; Stewart T Cole
Novel mutation in 16S rRNA associated with streptomycin dependence in Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 1995;39(3):769-70.
1995: E Cornillot; Brigitte Saint-Joanis; Georges DAUBE; S Katayama; P E Granum; B Canard; Stewart T Cole
The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid-borne.
Molecular microbiology 1995;15(4):639-47.
1995: S Poulet; Stewart T Cole
Characterization of the highly abundant polymorphic GC-rich-repetitive sequence (PGRS) present in Mycobacterium tuberculosis.
Archives of microbiology 1995;163(2):87-95.
1995: S Poulet; Stewart T Cole
Repeated DNA sequences in mycobacteria.
Archives of microbiology 1995;163(2):79-86.
1995: B Heym; Pedro Alzari; Nadine Honoré; Stewart T Cole
Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis.
Molecular microbiology 1995;15(2):235-45.
1994: Stewart T Cole
Mycobacterium tuberculosis: drug-resistance mechanisms.
Trends in microbiology 1994;2(10):411-5.
1994: Stewart T Cole
Mechanisms of drug resistance in Mycobacterium tuberculosis.
Immunobiology 1994;191(4-5):584-5.
1994: B Heym; Nadine Honoré; Chantal Truffot-Pernot; A Banerjee; Catherine Schurra; William R. Jacobs Jr.; Jan D A Van Embden; Jacques H Grosset; Stewart T Cole
Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study.
Lancet 1994;344(8918):293-8.
1994: Stewart T Cole; Isabelle Saint-Girons
Bacterial genomics.
FEMS microbiology reviews 1994;14(2):139-60.
1994: S Bergh; Stewart T Cole
MycDB: an integrated mycobacterial database.
Molecular microbiology 1994;12(4):517-34.
1994: B Canard; Thierry Garnier; Brigitte Saint-Joanis; Stewart T Cole
Molecular genetic analysis of the nagH gene encoding a hyaluronidase of Clostridium perfringens.
Molecular & general genetics : MGG 1994;243(2):215-24.
1994: H E Takiff; L Salazar; C Guerrero; W Philipp; W M Huang; B Kreiswirth; Stewart T Cole; William R. Jacobs Jr.; Amalio Telenti
Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.
Antimicrobial agents and chemotherapy 1994;38(4):773-80.
1994: Nadine Honoré; Stewart T Cole
Streptomycin resistance in mycobacteria.
Antimicrobial agents and chemotherapy 1994;38(2):238-42.
1993: Nadine Honoré; E Perrani; A Telenti; Jacques H Grosset; Stewart T Cole
A simple and rapid technique for the detection of rifampin resistance in Mycobacterium leprae.
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 1993;61(4):600-4.
1993: B Heym; Ying Zhang; S Poulet; D Young; Stewart T Cole
Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis.
Journal of bacteriology 1993;175(13):4255-9.
1993: N Honore; Stewart T Cole
Molecular basis of rifampin resistance in Mycobacterium leprae.
Antimicrobial agents and chemotherapy 1993;37(3):414-8.
1993: Karin Eiglmeier; Nadine Honoré; S A Woods; B Caudron; Stewart T Cole
Use of an ordered cosmid library to deduce the genomic organization of Mycobacterium leprae.
Molecular microbiology 1993;7(2):197-206.
1992: B Heym; Stewart T Cole
Isolation and characterization of isoniazid-resistant mutants of Mycobacterium smegmatis and M. aurum.
Research in microbiology 1992;143(7):721-30.
1992: B Canard; Brigitte Saint-Joanis; Stewart T Cole
Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringens.
Molecular microbiology 1992;6(11):1421-9.
1992: B Canard; Thierry Garnier; B Lafay; R Christen; Stewart T Cole
Phylogenetic analysis of the pathogenic anaerobe Clostridium perfringens using the 16S rRNA nucleotide sequence.
International journal of systematic bacteriology 1992;42(2):312-4.
1991: Thierry Garnier; B Canard; Stewart T Cole
Cloning, mapping, and molecular characterization of the rRNA operons of Clostridium perfringens.
Journal of bacteriology 1991;173(17):5431-8.
1991: Karin Eiglmeier; Nadine Honoré; Stewart T Cole
Towards the integration of foreign DNA into the chromosome of Mycobacterium leprae.
Research in microbiology 1991;142(6):617-22.
1990: S A Woods; Stewart T Cole
A family of dispersed repeats in Mycobacterium leprae.
Molecular microbiology 1990;4(10):1745-51.
1990: Nadine Honoré; Stewart T Cole
Nucleotide sequence of the aroP gene encoding the general aromatic amino acid transport protein of Escherichia coli K-12: homology with yeast transport proteins.
Nucleic acids research 1990;18(3):653.
1990: B Canard; Stewart T Cole
Lysogenic phages of Clostridium perfringens: mapping of the chromosomal attachment sites.
FEMS microbiology letters 1990;54(1-3):323-6.
1989: M H Nicolas; Vincent Jarlier; N Honore; A Philippon; Stewart T Cole
Molecular characterization of the gene encoding SHV-3 beta-lactamase responsible for transferable cefotaxime resistance in clinical isolates of Klebsiella pneumoniae.
Antimicrobial agents and chemotherapy 1989;33(12):2096-100.
1989: S A Woods; Stewart T Cole
A rapid method for the detection of potentially viable Mycobacterium leprae in human biopsies: a novel application of PCR.
FEMS microbiology letters 1989;53(3):305-9.
1989: Brigitte Saint-Joanis; Thierry Garnier; Stewart T Cole
Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities.
Molecular & general genetics : MGG 1989;219(3):453-60.
1989: B Canard; Stewart T Cole
Genome organization of the anaerobic pathogen Clostridium perfringens.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6676-80.
1989: Nadine Honoré; M H Nicolas; Stewart T Cole
Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer.
Molecular microbiology 1989;3(8):1121-30.
1989: Karin Eiglmeier; Nadine Honoré; S Iuchi; E C Lin; Stewart T Cole
Molecular genetic analysis of FNR-dependent promoters.
Molecular microbiology 1989;3(7):869-78.
1989: Stewart T Cole; Nadine Honoré
Transcription of the sulA-ompA region of Escherichia coli during the SOS response and the role of an antisense RNA molecule.
Molecular microbiology 1989;3(6):715-22.
1989: Stewart T Cole
A breath of fresh air--respiratory control demystified.
Research in microbiology 1989;140(4-5):277-9.
1988: Thierry Garnier; Stewart T Cole
Studies of UV-inducible promoters from Clostridium perfringens in vivo and in vitro.
Molecular microbiology 1988;2(5):607-14.
1988: Stewart T Cole; Karin Eiglmeier; S Ahmed; N Honore; L Elmes; W F Anderson; Joel Weiner
Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12.
Journal of bacteriology 1988;170(6):2448-56.
1988: Thierry Garnier; Stewart T Cole
Identification and molecular genetic analysis of replication functions of the bacteriocinogenic plasmid pIP404 from Clostridium perfringens.
Plasmid 1988;19(2):151-60.
1988: Thierry Garnier; Stewart T Cole
Complete nucleotide sequence and genetic organization of the bacteriocinogenic plasmid, pIP404, from Clostridium perfringens.
Plasmid 1988;19(2):134-50.
1987: Thierry Garnier; William Saurin; Stewart T Cole
Molecular characterization of the resolvase gene, res, carried by a multicopy plasmid from Clostridium perfringens: common evolutionary origin for prokaryotic site-specific recombinases.
Molecular microbiology 1987;1(3):371-6.
1987: Stewart T Cole
Nucleotide sequence and comparative analysis of the frd operon encoding the fumarate reductase of Proteus vulgaris. Extensive sequence divergence of the membrane anchors and absence of an frd-linked ampC cephalosporinase gene.
European journal of biochemistry / FEBS 1987;167(3):481-8.
1987: M H Nicolas; N Honore; Vincent Jarlier; A Philippon; Stewart T Cole
Molecular genetic analysis of cephalosporinase production and its role in beta-lactam resistance in clinical isolates of Enterobacter cloacae.
Antimicrobial agents and chemotherapy 1987;31(2):295-9.
1986: Nadine Honoré; M H Nicolas; Stewart T Cole
Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli.
The EMBO journal 1986;5(13):3709-14.
1986: Stewart T Cole; M H Nicolas
Beta-lactam resistance mechanisms in gram-negative bacteria.
Microbiological sciences 1986;3(11):334-9.