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Daniel Alkon

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Physiology

Anatomy

Living Beings

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Disorders

Alzheimer Disease

Concepts & Ideas

Membrane Potentials

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Co-Publications
Name
33
Nelson, Thomas
26
Sun, Miao-Kun
20
Schreurs, Bernard
16
Etcheberrigaray, René
14
Cavallaro, Sebastiano
12
Kuzirian, Alan
12
Matzel, Louis
10
Gusev, Pavel
8
Epstein, Herman
8
McPhie, Donna
8
Sakakibara, Manabu
7
Pascale, Alessia
6
Zhao, Wei-Qin
6
Govoni, Stefano
6
Favit, Antonella

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Publications

TOP 3
Sun Miao-Kun; Hongpaisan Jarin; Alkon Daniel L
Postischemic PKC activation rescues retrograde and anterograde long-term memory.
Xu Changqing; Cui Changhai; Alkon Daniel L
Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors.
Khan Tapan K; Nelson Thomas J; Verma Vishal A; Wender Paul A; Alkon Daniel L
A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Abeta-induced biomarker abnormality on cultured fibroblasts.

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All Publications

2009: Sun Miao-Kun; Hongpaisan Jarin; Alkon Daniel L
Postischemic PKC activation rescues retrograde and anterograde long-term memory.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(34):14676-80.
2009: Xu Changqing; Cui Changhai; Alkon Daniel L
Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors.
Hippocampus 2009;19(8):706-17.
2009: Khan Tapan K; Nelson Thomas J; Verma Vishal A; Wender Paul A; Alkon Daniel L
A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Abeta-induced biomarker abnormality on cultured fibroblasts.
Neurobiology of disease 2009;34(2):332-9.
2009: Nelson T J; Alkon D L
Neuroprotective versus tumorigenic protein kinase C activators.
Trends in biochemical sciences 2009;34(3):136-45.
2008: Sun Miao-Kun; Hongpaisan Jarin; Nelson Thomas J; Alkon Daniel L
Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13620-5.
2008: Sun Miao-Kun; Alkon Daniel L
Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats.
Behavioural pharmacology 2008;19(4):334-8.
2008: Micale Vincenzo; Scapagnini Giovanni; Colombrita Claudia; Mazzola Carmen; Alkon Daniel L; Drago Filippo
Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(6):462-71.
2008: Wang Desheng; Darwish Deya S; Schreurs Bernard G; Alkon Daniel L
Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response.
Behavioural pharmacology 2008;19(3):245-56.
2008: Nelson Thomas J; Sun Miao-Kun; Hongpaisan Jarin; Alkon Daniel L
Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair.
European journal of pharmacology 2008;585(1):76-87.
2008: Sun Miao-Kun; Alkon Daniel L
Synergistic effects of chronic bryostatin-1 and alpha-tocopherol on spatial learning and memory in rats.
European journal of pharmacology 2008;584(2-3):328-37.
2008: Sun Miao-Kun; Alkon Daniel L
Effects of 4-methylcatechol on spatial memory and depression.
Neuroreport 2008;19(3):355-9.
2007: Hongpaisan Jarin; Alkon Daniel L
A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19571-6.
2007: Nelson Thomas J; Alkon Daniel L
Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid.
The Journal of biological chemistry 2007;282(43):31238-49.
2007: Alkon Daniel L; Sun Miao-Kun; Nelson Thomas J
PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease.
Trends in pharmacological sciences 2007;28(2):51-60.
2006: Khan Tapan K; Alkon Daniel L
An internally controlled peripheral biomarker for Alzheimer's disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(35):13203-7.
2006: Dufour Franck; Liu Qi-Ying; Gusev Pavel; Alkon Daniel; Atzori Marco
Cholesterol-enriched diet affects spatial learning and synaptic function in hippocampal synapses.
Brain research 2006;1103(1):88-98.
2006: Sun Miao-Kun; Alkon Daniel L
Links between Alzheimer's disease and diabetes.
Drugs of today (Barcelona, Spain : 1998) 2006;42(7):481-9.
2006: Sun Miao-Kun; Alkon Daniel L
Protein kinase C pharmacology: perspectives on therapeutic potentials as antidementic and cognitive agents.
Recent patents on CNS drug discovery 2006;1(2):147-56.
2006: Kuzirian A M; Epstein H T; Gagliardi C J; Nelson T J; Sakakibara M; Taylor C; Scioletti A B; Alkon D L
Bryostatin enhancement of memory in Hermissenda.
The Biological bulletin 2006;210(3):201-14.
2006: Tan Dong Ping; Liu Qi-Ying; Koshiya Naohiro; Gu Hua; Alkon Daniel
Enhancement of long-term memory retention and short-term synaptic plasticity in cbl-b null mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):5125-30.
2006: Sun Miao-Kun; Alkon Daniel L
Differential gender-related vulnerability to depression induction and converging antidepressant responses in rats.
The Journal of pharmacology and experimental therapeutics 2006;316(2):926-32.
2006: Sun Miao-Kun; Alkon Daniel L
Links between Alzheimer's disease and diabetes.
Timely topics in medicine. Cardiovascular diseases 2006;10():E24.
2006: Sun Miao-Kun; Alkon Daniel L
Bryostatin-1: pharmacology and therapeutic potential as a CNS drug.
CNS drug reviews 2006;12(1):1-8.
2005: Dou Jing-Tao; Chen Min; Dufour Franck; Alkon Daniel L; Zhao Wei-Qin
Insulin receptor signaling in long-term memory consolidation following spatial learning.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(6):646-55.
2005: Alkon Daniel L; Epstein Herman; Kuzirian Alan; Bennett M Catherine; Nelson Thomas J
Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16432-7.
2005: Nelson T J; Alkon D L
Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration.
Biochemical Society transactions 2005;33(Pt 5):1033-6.
2005: Sun Miao-Kun; Alkon Daniel L
Protein kinase C isozymes: memory therapeutic potential.
Current drug targets. CNS and neurological disorders 2005;4(5):541-52.
2005: Gusev Pavel A; Cui Changhai; Alkon Daniel L; Gubin Alexander N
Topography of Arc/Arg3.1 mRNA expression in the dorsal and ventral hippocampus induced by recent and remote spatial memory recall: dissociation of CA3 and CA1 activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(41):9384-97.
2005: Pascale Alessia; Amadio Marialaura; Scapagnini Giovanni; Lanni Cristina; Racchi Marco; Provenzani Alessandro; Govoni Stefano; Alkon Daniel L; Quattrone Alessandro
Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(34):12065-70.
2005: Zohar O; Pick C G; Cavallaro S; Chapman J; Katzav A; Milman A; Alkon D L
Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice.
Neurobiology of aging 2005;26(8):1167-75.
2005: Sun Miao-Kun; Alkon Daniel L
Dual effects of bryostatin-1 on spatial memory and depression.
European journal of pharmacology 2005;512(1):43-51.
2005: Nelson Thomas J; Alkon Daniel L
Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.
The Journal of biological chemistry 2005;280(8):7377-87.
2004: Cavallaro Sebastiano; D'Agata Velia; Alessi Enrico; Coffa Salvatore; Alkon Daniel L; Manickam Pachiappan; Ciotti Maria Teresa; Possenti Roberta; Bonini Paolo; Marlier Lionel; Calissano Pietro
Gene expression profiles of apoptotic neurons.
Genomics 2004;84(3):485-96.
2004: Sun Miao-Kun; Alkon Daniel L
Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats.
Journal of Alzheimer's disease : JAD 2004;6(4):355-66; discussion 443-9.
2004: Amadio Marialaura; Govoni Stefano; Alkon Daniel L; Pascale Alessia
Emerging targets for the pharmacology of learning and memory.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;50(2):111-22.
2004: Etcheberrigaray René; Tan Mathew; Dewachter Ilse; Kuipéri Cuno; Van der Auwera Ingrid; Wera Stefaan; Qiao Lixin; Bank Barry; Nelson Thomas J; Kozikowski Alan P; Van Leuven Fred; Alkon Daniel L
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):11141-6.
2004: Zhao Wei-Qin; Chen Hui; Quon Michael J; Alkon Daniel L
Insulin and the insulin receptor in experimental models of learning and memory.
European journal of pharmacology 2004;490(1-3):71-81.
2004: Pascale Alessia; Alkon Daniel L; Grimaldi Maurizio
Translocation of protein kinase C-betaII in astrocytes requires organized actin cytoskeleton and is not accompanied by synchronous RACK1 relocation.
Glia 2004;46(2):169-82.
2004: Pascale Alessia; Gusev Pavel A; Amadio Marialaura; Dottorini Tania; Govoni Stefano; Alkon Daniel L; Quattrone Alessandro
Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1217-22.
2004: Epstein Herman T; Kuzirian Alan M; Child Frank M; Alkon Daniel L
Two different biological configurations for long-term memory.
Neurobiology of learning and memory 2004;81(1):12-8.
2004: Sun M-K; Alkon D L
Induced depressive behavior impairs learning and memory in rats.
Neuroscience 2004;129(1):129-39.
2004: Nelson Thomas J; Backlund Peter S; Alkon Daniel L
Hippocampal protein-protein interactions in spatial memory.
Hippocampus 2004;14(1):46-57.
2003: Zhao Wei-Qin; Feng Christina; Alkon Daniel L
Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts.
Neurobiology of disease 2003;14(3):458-69.
2003: Dou Jingtao; Cui Changhai; Dufour Franck; Alkon Daniel L; Zhao Wei-Qin
Gene expression of alpha-endosulfine in the rat brain: correlative changes with aging, learning and stress.
Journal of neurochemistry 2003;87(5):1086-100.
2003: Kuzirian A M; Child F M; Epstein H T; Motta M E; Oldenburg C E; Alkon D L
Training alone, not the tripeptide RGD, modulates calexcitin in Hermissenda.
The Biological bulletin 2003;205(2):220-2.
2003: Child F M; Epstein H T; Kuzirian A M; Alkon D L
Memory reconsolidation in Hermissenda.
The Biological bulletin 2003;205(2):218-9.
2003: Nelson Thomas J; Quattrone Alessandro; Kim Jeongho; Pacini Alessandra; Cesati Valentina; Alkon Daniel L
Calcium-regulated GTPase activity in the calcium-binding protein calexcitin.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2003;135(4):627-38.
2003: Zohar Ofer; Cavallaro Sebastiano; D'Agata Velia; Alkon Daniel L
Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain.
Brain research. Molecular brain research 2003;115(1):63-8.
2003: Sun Miao-Kun; Alkon Daniel L
Open space swimming test to index antidepressant activity.
Journal of neuroscience methods 2003;126(1):35-40.
2003: Colombrita Claudia; Calabrese Vittorio; Stella Anna Maria Giuffrida; Mattei Francesca; Alkon Daniel L; Scapagnini Giovanni
Regional rat brain distribution of heme oxygenase-1 and manganese superoxide dismutase mRNA: relevance of redox homeostasis in the aging processes.
Experimental biology and medicine (Maywood, N.J.) 2003;228(5):517-24.
2003: Zhao Wei-Qin; Alkon Daniel L; Ma Wu
c-Src protein tyrosine kinase activity is required for muscarinic receptor-mediated DNA synthesis and neurogenesis via ERK1/2 and c-AMP-responsive element-binding protein signaling in neural precursor cells.
Journal of neuroscience research 2003;72(3):334-42.
2003: Epstein Herman T; Child Frank M; Kuzirian Alan M; Alkon Daniel L
Time windows for effects of protein synthesis inhibitors on Pavlovian conditioning in Hermissenda: behavioral aspects.
Neurobiology of learning and memory 2003;79(2):127-31.
2003: Zhao Wei-Qin; Chen Gina H; Chen Hui; Pascale Alessia; Ravindranath Lakshmi; Quon Michael J; Alkon Daniel L
Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.
The Journal of biological chemistry 2003;278(6):4205-15.
2002: Sun Miao-Kun; Alkon Daniel L
Depressed or demented: common CNS drug targets?!
Current drug targets. CNS and neurological disorders 2002;1(6):575-92.
2002: Cavallaro Sebastiano; D'Agata Velia; Manickam Pachiappan; Dufour Franck; Alkon Daniel L
Memory-specific temporal profiles of gene expression in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(25):16279-84.
2002: Scapagnini Giovanni; D'Agata Velia; Calabrese Vittorio; Pascale Alessia; Colombrita Claudia; Alkon Daniel; Cavallaro Sebastiano
Gene expression profiles of heme oxygenase isoforms in the rat brain.
Brain research 2002;954(1):51-9.
2002: Cavallaro Sebastiano; Dagata Velia; Alkon Daniel L
Programs of gene expression during the laying down of memory formation as revealed by DNA microarrays.
Neurochemical research 2002;27(10):1201-7.
2002: Zhao Wei-Qin; Ravindranath Lakshmi; Mohamed Ali S; Zohar Ofer; Chen Gina H; Lyketsos Constantine G; Etcheberrigaray René; Alkon Daniel L
MAP kinase signaling cascade dysfunction specific to Alzheimer's disease in fibroblasts.
Neurobiology of disease 2002;11(1):166-83.
2002: D'Agata Velia; Warren Stephen T; Zhao Weiqin; Torre Enrique R; Alkon Daniel L; Cavallaro Sebastiano
Gene expression profiles in a transgenic animal model of fragile X syndrome.
Neurobiology of disease 2002;10(3):211-8.
2002: Sun Miao-Kun; Alkon Daniel L
Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35).
Journal of neurophysiology 2002;87(5):2441-9.
2002: Nelson Thomas J; Backlund Peter S; Yergey Alfred L; Alkon Daniel L
Isolation of protein subpopulations undergoing protein-protein interactions.
Molecular & cellular proteomics : MCP 2002;1(3):253-9.
2002: Sun Miao-Kun; Alkon Daniel L
Carbonic anhydrase gating of attention: memory therapy and enhancement.
Trends in pharmacological sciences 2002;23(2):83-9.
2002: Sun Miao-Kun; Xu Hui; Alkon Daniel L
Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats.
The Journal of pharmacology and experimental therapeutics 2002;300(2):408-16.
2002: Scapagnini G; Ravagna A; Bella R; Colombrita C; Pennisi G; Calvani M; Alkon D; Calabrese V
Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine.
International journal of tissue reactions 2002;24(3):89-96.
2001: Kuzirian A M; Epstein H T; Buck D; Child F M; Nelson T; Alkon D L
Pavlovian conditioning-specific increases of the Ca2+- and GTP-binding protein, calexcitin in identified Hermissenda visual cells.
Journal of neurocytology 2001;30(12):993-1008.
2001: Schreurs B G; Alkon D L
Imaging learning and memory: classical conditioning.
The Anatomical record 2001;265(6):257-73.
2001: Quattrone A; Pascale A; Nogues X; Zhao W; Gusev P; Pacini A; Alkon D L
Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11668-73.
2001: Gusev P A; Alkon D L
Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells.
Journal of neurophysiology 2001;86(2):881-99.
2001: Sun M K; Alkon D L
Pharmacological enhancement of synaptic efficacy, spatial learning, and memory through carbonic anhydrase activation in rats.
The Journal of pharmacology and experimental therapeutics 2001;297(3):961-7.
2001: Zhao W Q; Alkon D L
Role of insulin and insulin receptor in learning and memory.
Molecular and cellular endocrinology 2001;177(1-2):125-34.
2001: Cavallaro S; Schreurs B G; Zhao W; D'Agata V; Alkon D L
Gene expression profiles during long-term memory consolidation.
The European journal of neuroscience 2001;13(9):1809-15.
2001: Grimaldi M; Atzori M; Ray P; Alkon D L
Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(9):3135-43.
2001: Sun M; Dahl D; Alkon D L
Heterosynaptic transformation of GABAergic gating in the hippocampus and effects of carbonic anhydrase inhibition.
The Journal of pharmacology and experimental therapeutics 2001;296(3):811-7.
2001: Sun M K; Zhao W Q; Nelson T J; Alkon D L
Theta rhythm of hippocampal CA1 neuron activity: gating by GABAergic synaptic depolarization.
Journal of neurophysiology 2001;85(1):269-79.
2000: Sun M K; Nelson T J; Alkon D L
Functional switching of GABAergic synapses by ryanodine receptor activation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12300-5.
2000: Favit A; Grimaldi M; Alkon D L
Prevention of beta-amyloid neurotoxicity by blockade of the ubiquitin-proteasome proteolytic pathway.
Journal of neurochemistry 2000;75(3):1258-63.
2000: Zhao W; Cavallaro S; Gusev P; Alkon D L
Nonreceptor tyrosine protein kinase pp60c-src in spatial learning: synapse-specific changes in its gene expression, tyrosine phosphorylation, and protein-protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):8098-103.
2000: Tomsic D; Alkon D L
Background illumination effects upon in vitro conditioning in Hermissenda.
Neurobiology of learning and memory 2000;74(1):56-64.
2000: Zhao W; Meiri N; Xu H; Cavallaro S; Quattrone A; Zhang L; Alkon D L
Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(2):290-300.
1999: Zhao W; Chen H; Xu H; Moore E; Meiri N; Quon M J; Alkon D L
Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats.
The Journal of biological chemistry 1999;274(49):34893-902.
1999: Grimaldi M; Favit A; Alkon D L
cAMP-induced cytoskeleton rearrangement increases calcium transients through the enhancement of capacitative calcium entry.
The Journal of biological chemistry 1999;274(47):33557-64.
1999: Alkon D L
Ionic conductance determinants of synaptic memory nets and their implications for Alzheimer's disease.
Journal of neuroscience research 1999;58(1):24-32.
1999: Nelson T J; Zhao W Q; Yuan S; Favit A; Pozzo-Miller L; Alkon D L
Calexcitin interaction with neuronal ryanodine receptors.
The Biochemical journal 1999;341 ( Pt 2)():423-33.
1999: Sun M K; Nelson T J; Xu H; Alkon D L
Calexcitin transformation of GABAergic synapses: from excitation filter to amplifier.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):7023-8.
1998: Alkon D L; Nelson T J; Zhao W; Cavallaro S
Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade.
Trends in neurosciences 1998;21(12):529-37.
1998: Meiri N; Sun M K; Segal Z; Alkon D L
Memory and long-term potentiation (LTP) dissociated: normal spatial memory despite CA1 LTP elimination with Kv1.4 antisense.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):15037-42.
1998: Kuzirian A M; Epstein H T; Nelson T J; Rafferty N S; Alkon D L
Lead, learning, and calexcitin in Hermissenda.
The Biological bulletin 1998;195(2):198-201.
1998: Alkon D L; Favit A; Nelson T
Evolution of adaptive neural networks: the role of voltage-dependent K+ channels.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;119(3):204-11.
1998: Etcheberrigaray R; Hirashima N; Nee L; Prince J; Govoni S; Racchi M; Tanzi R E; Alkon D L
Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families.
Neurobiology of disease 1998;5(1):37-45.
1998: Schreurs B G; Gusev P A; Tomsic D; Alkon D L; Shi T
Intracellular correlates of acquisition and long-term memory of classical conditioning in Purkinje cell dendrites in slices of rabbit cerebellar lobule HVI.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5498-507.
1998: Favit A; Grimaldi M; Nelson T J; Alkon D L
Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5562-7.
1998: Zohar O; Ikeda M; Shinagawa H; Inoue H; Nakamura H; Elbaum D; Alkon D L; Yoshioka T
Thermal imaging of receptor-activated heat production in single cells.
Biophysical journal 1998;74(1):82-9.
1998: Gasparini L; Racchi M; Binetti G; Trabucchi M; Solerte S B; Alkon D; Etcheberrigaray R; Gibson G; Blass J; Paoletti R; Govoni S
Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(1):17-34.
1998: Alkon D L
Molecular specificity of synaptic changes responsible for associative memory.
Advances in experimental medicine and biology 1998;446():1-15.
1998: Ascoli G A; Pergami P; Luu K X; Alkon D L; Bramanti E; Bertucci C; Di Bari L; Salvadori P
Use of CD and FT-IR to determine the secondary structure of purified proteins in the low-microgram range.
Enantiomer 1998;3(4-5):371-81.
1998: Nelson T J; Gusev P A; Alkon D L
Identification of ion channel regulating proteins by patch-clamp analysis.
Methods in enzymology 1998;293():194-201.
1997: Ascoli G A; Luu K X; Olds J L; Nelson T J; Gusev P A; Bertucci C; Bramanti E; Raffaelli A; Salvadori P; Alkon D L
Secondary structure and Ca2+-induced conformational change of calexcitin, a learning-associated protein.
The Journal of biological chemistry 1997;272(40):24771-9.
1997: Cavallaro S; Meiri N; Yi C L; Musco S; Ma W; Goldberg J; Alkon D L
Late memory-related genes in the hippocampus revealed by RNA fingerprinting.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9669-73.
1997: Meiri N; Ghelardini C; Tesco G; Galeotti N; Dahl D; Tomsic D; Cavallaro S; Quattrone A; Capaccioli S; Bartolini A; Alkon D L
Reversible antisense inhibition of Shaker-like Kv1.1 potassium channel expression impairs associative memory in mouse and rat.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4430-4.
1997: Schreurs B G; Tomsic D; Gusev P A; Alkon D L
Dendritic excitability microzones and occluded long-term depression after classical conditioning of the rabbit's nictitating membrane response.
Journal of neurophysiology 1997;77(1):86-92.
1996: Nelson T J; Cavallaro S; Yi C L; McPhie D; Schreurs B G; Gusev P A; Favit A; Zohar O; Kim J; Beushausen S; Ascoli G; Olds J; Neve R; Alkon D L
Calexcitin: a signaling protein that binds calcium and GTP, inhibits potassium channels, and enhances membrane excitability.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):13808-13.
1996: Schachter J B; Lester D S; Alkon D L
Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity.
Biochimica et biophysica acta 1996;1291(2):167-76.
1996: Hirashima N; Etcheberrigaray R; Bergamaschi S; Racchi M; Battaini F; Binetti G; Govoni S; Alkon D L
Calcium responses in human fibroblasts: a diagnostic molecular profile for Alzheimer's disease.
Neurobiology of aging 1996;17(4):549-55.
1996: Dettmar H P; Barbour G S; Blackwell K T; Vogl T P; Alkon D L; Fry F S; Totah J E; Chambers T L
Orange juice classification with a biologically based neural network.
Computers & chemistry 1996;20(2):261-6.
1996: Schreurs B G; Oh M M; Alkon D L
Pairing-specific long-term depression of Purkinje cell excitatory postsynaptic potentials results from a classical conditioning procedure in the rabbit cerebellar slice.
Journal of neurophysiology 1996;75(3):1051-60.
1996: Etcheberrigaray R; Payne J L; Alkon D L
Soluble beta-amyloid induces Alzheimer's disease features in human fibroblasts and in neuronal tissues.
Life sciences 1996;59(5-6):491-8.
1995: Nelson T J; Alkon D L
Phosphorylation of the conditioning-associated GTP-binding protein cp20 by protein kinase C.
Journal of neurochemistry 1995;65(5):2350-7.
1995: Collin C; Devane W A; Dahl D; Lee C J; Axelrod J; Alkon D L
Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10167-71.
1995: Wolozin B; Hirashima N; Luo Y; Li Y H; Alkon D L; Etcheberrigaray R; Sunderland T
Transforming growth factor beta induces a beta-responsive calcium fluxes in neurons.
Neuroreport 1995;6(10):1429-33.
1995: Luo Y Q; Hirashima N; Li Y H; Alkon D L; Sunderland T; Etcheberrigaray R; Wolozin B
Physiological levels of beta-amyloid increase tyrosine phosphorylation and cytosolic calcium.
Brain research 1995;681(1-2):65-74.
1995: Golski S; Olds J L; Mishkin M; Olton D S; Alkon D L
Protein kinase C in the hippocampus is altered by spatial but not cued discriminations: a component task analysis.
Brain research 1995;676(1):53-62.
1995: Kim C S; Han Y F; Etcheberrigaray R; Nelson T J; Olds J L; Yoshioka T; Alkon D L
Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):3060-4.
1995: Schreurs B G; Oh M M; Hirashima C; Alkon D L
Conditioning-specific modification of the rabbit's unconditioned nictitating membrane response.
Behavioral neuroscience 1995;109(1):24-33.
1995: Alkon D L
Molecular mechanisms of associative memory and their clinical implications.
Behavioural brain research 1995;66(1-2):151-60.
1994: Etcheberrigaray E; Gibson G E; Alkon D L
Molecular mechanisms of memory and the pathophysiology of Alzheimer's disease.
Annals of the New York Academy of Sciences 1994;747():245-55.
1994: Huang H M; Martins R; Gandy S; Etcheberrigaray R; Ito E; Alkon D L; Blass J; Gibson G
Use of cultured fibroblasts in elucidating the pathophysiology and diagnosis of Alzheimer's disease.
Annals of the New York Academy of Sciences 1994;747():225-44.
1994: Lester D S; Olds J L; Schreurs B G; McPhie D; Bramham C R; Alkon D L
Incorporation of fluorescent lipids into living rabbit hippocampal and cerebellar slices.
NeuroImage 1994;1(4):264-75.
1994: Nelson T J; Yoshioka T; Toyoshima S; Han Y F; Alkon D L
Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9287-91.
1994: Sakakibara M; Alkon D L; Kouchi T; Inoue H; Yoshioka T
Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor.
Biochemical and biophysical research communications 1994;202(1):299-306.
1994: Bramham C R; Alkon D L; Lester D S
Arachidonic acid and diacylglycerol ACT synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus.
Neuroscience 1994;60(3):737-43.
1994: Etcheberrigaray R; Ito E; Kim C S; Alkon D L
Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels.
Science (New York, N.Y.) 1994;264(5156):276-9.
1994: Ito E; Oka K; Collin C; Schreurs B G; Sakakibara M; Alkon D L
Intracellular calcium signals are enhanced for days after Pavlovian conditioning.
Journal of neurochemistry 1994;62(4):1337-44.
1994: Olds J L; Bhalla U S; McPhie D L; Lester D S; Bower J M; Alkon D L
Lateralization of membrane-associated protein kinase C in rat piriform cortex: specific to operant training cues in the olfactory modality.
Behavioural brain research 1994;61(1):37-46.
1994: Ito E; Oka K; Etcheberrigaray R; Nelson T J; McPhie D L; Tofel-Grehl B; Gibson G E; Alkon D L
Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):534-8.
1993: Alkon D L; Collin C; Ito E; Lee C J; Nelson T J; Oka K; Sakakibara M; Schreurs B G; Yoshioka T
Molecular and biophysical steps in the storage of associative memory.
Annals of the New York Academy of Sciences 1993;707():500-4.
1993: Schreurs B G; Alkon D L
Rabbit cerebellar slice analysis of long-term depression and its role in classical conditioning.
Brain research 1993;631(2):235-40.
1993: Alkon D L; Etcheberrigaray R; Rojas E
Distribution of voltage sensors in mammalian outer hair cells.
Biophysical journal 1993;65(5):1755-6.
1993: Etcheberrigaray R; Ito E; Oka K; Tofel-Grehl B; Gibson G E; Alkon D L
Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8209-13.
1993: Craig A M; Olds J L; Schreurs B G; Scharenberg A M; Alkon D L
Quantitative distribution of protein kinase C alpha, beta, gamma, and epsilon mRNAs in the hippocampus of control and nictitating membrane conditioned rabbits.
Brain research. Molecular brain research 1993;19(4):269-76.
1993: Alkon D L; Anderson M J; Kuzirian A J; Rogers D F; Fass D M; Collin C; Nelson T J; Kapetanovic I M; Matzel L D
GABA-mediated synaptic interaction between the visual and vestibular pathways of Hermissenda.
Journal of neurochemistry 1993;61(2):556-66.
1993: Sakakibara M; Ikeno H; Usui S; Collin C; Alkon D L
Reconstruction of ionic currents in a molluscan photoreceptor.
Biophysical journal 1993;65(1):519-27.
1993: Sunayashiki-Kusuzaki K; Lester D S; Schreurs B G; Alkon D L
Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4286-9.
1993: Moshiach S; Nelson T J; Sanchez-Andres J V; Sakakibara M; Alkon D L
G-protein effects on retrograde axonal transport.
Brain research 1993;605(2):298-304.
1993: McPhie D L; Matzel L D; Olds J L; Lester D S; Kuzirian A M; Alkon D L
Cell specificity of molecular changes during memory storage.
Journal of neurochemistry 1993;60(2):646-51.
1993: Werness S A; Fay S D; Blackwell K T; Vogl T P; Alkon D L
Associative learning in a network model of Hermissenda crassicornis. II. Experiments.
Biological cybernetics 1993;69(1):19-28.
1993: Olds J L; Alkon D L
Protein kinase C: a nexus in the biochemical events that underlie associative learning.
Acta neurobiologiae experimentalis 1993;53(1):197-207.
1992: Matzel L D; Collin C; Alkon D L
Biophysical and behavioral correlates of memory storage, degradation, and reactivation.
Behavioral neuroscience 1992;106(6):954-63.
1992: Alkon D L; Sánchez-Andrés J V; Ito E; Oka K; Yoshioka T; Collin C
Long-term transformation of an inhibitory into an excitatory GABAergic synaptic response.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):11862-6.
1992: Schreurs B G; Sanchez-Andres J V; Alkon D L
GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice.
Brain research 1992;597(1):99-107.
1992: Etcheberrigaray R; Matzel L D; Lederhendler I I; Alkon D L
Classical conditioning and protein kinase C activation regulate the same single potassium channel in Hermissenda crassicornis photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7184-8.
1992: Werness S A; Fay S D; Blackwell K T; Vogl T P; Alkon D L
Associative learning in a network model of Hermissenda crassicornis. I. Theory.
Biological cybernetics 1992;68(2):125-33.
1992: Collin C; Alkon D L
Neural correlates of memory storage. The role of ion channels.
Ion channels 1992;3():159-75.
1992: Collin C; Ito E; Oka K; Yoshioka T; Sánchez-Andrés J V; Matzel L D; Alkon D L
The role of calcium in prolonged modification of a GABAergic synapse.
Journal of physiology, Paris 1992;86(1-3):139-45.
1991: Nelson T J; Sanchez-Andres J V; Schreurs B G; Alkon D L
Classical conditioning-induced changes in low-molecular-weight GTP-binding proteins in rabbit hippocampus.
Journal of neurochemistry 1991;57(6):2065-9.
1991: Lester D S; Collin C; Etcheberrigaray R; Alkon D L
Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo.
Biochemical and biophysical research communications 1991;179(3):1522-8.
1991: Scharenberg A M; Olds J L; Schreurs B G; Craig A M; Alkon D L
Protein kinase C redistribution within CA3 stratum oriens during acquisition of nictitating membrane conditioning in the rabbit.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6637-41.
1991: Matzel L D; Alkon D L
GABA-induced potentiation of neuronal excitability occurs during contiguous pairings with intracellular calcium elevation.
Brain research 1991;554(1-2):77-84.
1991: Schreurs B G; Sanchez-Andres J V; Alkon D L
Learning-specific differences in Purkinje-cell dendrites of lobule HVI (Lobulus simplex): intracellular recording in a rabbit cerebellar slice.
Brain research 1991;548(1-2):18-22.
1991: Sanchez-Andres J V; Alkon D L
Voltage-clamp analysis of the effects of classical conditioning on the hippocampus.
Journal of neurophysiology 1991;65(4):796-807.
1991: Olds J L; Alkon D L
A role for protein kinase C in associative learning.
The New biologist 1991;3(1):27-35.
1991: Alkon D L; Matzel L D; Collin C
Molecular mechanisms of memory and drug dependence.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1991;1():35-7.
1991: Nelson T J; Alkon D L
GTP-binding proteins and potassium channels involved in synaptic plasticity and learning.
Molecular neurobiology 1991;5(2-4):315-28.
1990: Collin C; Papageorge A G; Lowy D R; Alkon D L
Early enhancement of calcium currents by H-ras oncoproteins injected into Hermissenda neurons.
Science (New York, N.Y.) 1990;250(4988):1743-5.
1990: Olds J L; Golski S; McPhie D L; Olton D; Mishkin M; Alkon D L
Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(11):3707-13.
1990: Lederhendler I I; Etcheberrigaray R; Yamoah E N; Matzel L D; Alkon D L
Outgrowths from Hermissenda photoreceptor somata are associated with activation of protein kinase C.
Brain research 1990;534(1-2):195-200.
1990: Matzel L D; Schreurs B G; Alkon D L
Pavlovian conditioning of distinct components of Hermissenda's responses to rotation.
Behavioral and neural biology 1990;54(2):131-45.
1990: Collin C; Papageorge A G; Sakakibara M; Huddie P L; Lowy D R; Alkon D L
Early regulation of membrane excitability by ras oncogene proteins.
Biophysical journal 1990;58(3):785-90.
1990: Matzel L D; Schreurs B G; Lederhendler I; Alkon D L
Acquisition of conditioned associations in Hermissenda: additive effects of contiguity and the forward interstimulus interval.
Behavioral neuroscience 1990;104(4):597-606.
1990: Matzel L D; Lederhendler I I; Alkon D L
Regulation of short-term associative memory by calcium-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(7):2300-7.
1990: Alkon D L; Nelson T J
Specificity of molecular changes in neurons involved in memory storage.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(6):1567-76.
1990: Lederhendler I I; Collin C; Alkon D L
Sequential changes of potassium currents in Hermissenda type B photoreceptor during early stages of classical conditioning.
Neuroscience letters 1990;110(1-2):28-33.
1990: Nelson T J; Collin C; Alkon D L
Isolation of a G protein that is modified by learning and reduces potassium currents in Hermissenda.
Science (New York, N.Y.) 1990;247(4949 Pt 1):1479-83.
1990: Alkon D L; Ikeno H; Dworkin J; McPhie D L; Olds J L; Lederhendler I; Matzel L; Schreurs B G; Kuzirian A; Collin C
Contraction of neuronal branching volume: an anatomic correlate of Pavlovian conditioning.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1611-4.
1990: Nelson T J; Alkon D L
Specific high molecular weight mRNAs induced by associative learning in Hermissenda.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):269-73.
1990: Alkon D L; Blackwell K T; Barbour G S; Rigler A K; Vogl T P
Pattern-recognition by an artificial network derived from biologic neuronal systems.
Biological cybernetics 1990;62(5):363-76.
1990: Alkon D L
Biophysics of memory.
Progress in clinical and biological research 1990;334():273-7.
1989: Akase E; Alkon D L; Disterhoft J F
Hippocampal lesions impair memory of short-delay conditioned eye blink in rabbits.
Behavioral neuroscience 1989;103(5):935-43.
1989: Lederhendler I I; Alkon D L
The interstimulus interval and classical conditioning in the marine snail Hermissenda crassicornis.
Behavioural brain research 1989;35(1):75-80.
1989: Olds J L; Anderson M L; McPhie D L; Staten L D; Alkon D L
Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus.
Science (New York, N.Y.) 1989;245(4920):866-9.
1989: Alkon D L
Memory storage and neural systems.
Scientific American 1989;261(1):42-50.
1989: Coulter D A; Lo Turco J J; Kubota M; Disterhoft J F; Moore J W; Alkon D L
Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells.
Journal of neurophysiology 1989;61(5):971-81.
1989: Bank B; LoTurco J J; Alkon D L
Learning-induced activation of protein kinase C. A molecular memory trace.
Molecular neurobiology 1989;3(1-2):55-70.
1988: Collin C; Ikeno H; Harrigan J F; Lederhendler I; Alkon D L
Sequential modification of membrane currents with classical conditioning.
Biophysical journal 1988;54(5):955-60.
1988: Disterhoft J F; Golden D T; Read H L; Coulter D A; Alkon D L
AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response.
Brain research 1988;462(1):118-25.
1988: Nelson T J; Alkon D L
Prolonged RNA changes in the Hermissenda eye induced by classical conditioning.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7800-4.
1988: Alkon D L; Naito S; Kubota M; Chen C; Bank B; Smallwood J; Gallant P; Rasmussen H
Regulation of Hermissenda K+ channels by cytoplasmic and membrane-associated C-kinase.
Journal of neurochemistry 1988;51(3):903-17.
1988: Bank B; DeWeer A; Kuzirian A M; Rasmussen H; Alkon D L
Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(6):1988-92.
1988: LoTurco J L; Coulter D A; Alkon D L
Enhancement of synaptic potentials in rabbit CA1 pyramidal neurons following classical conditioning.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1672-6.
1988: Alkon D L; Rasmussen H
A spatial-temporal model of cell activation.
Science (New York, N.Y.) 1988;239(4843):998-1005.
1988: Bank B; Nelson T; Alkon D L
Molecular mechanisms of associative learning in mammal and mollusc.
Journal de physiologie 1988;83(3):119-25.
1987: Alkon D L; Bank B; Naito S; Chen C; Ram J
Inhibition of protein synthesis prolongs Ca2+-mediated reduction of K+ currents in molluscan neurons.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6948-52.
1987: Sakakibara M; Collin C; Kuzirian A; Alkon D L; Heldman E; Naito S; Lederhendler I
Effects of alpha 2-adrenergic agonists and antagonists on photoreceptor membrane currents.
Journal of neurochemistry 1987;48(2):405-16.
1987: Alkon D L; Naito S
Long-term synergistic regulation of ionic channels by C-kinase and Ca2+/CaM-type II kinase.
Advances in experimental medicine and biology 1987;221():275-90.
1986: Alkon D L; Sakakibara M; Naito S; Heldman E; Lederhendler I
The role of neurochemical modulation in learning.
Neuroscience research 1986;3(6):487-97.
1986: Disterhoft J F; Coulter D A; Alkon D L
Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2733-7.

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