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Sean Colgan

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Sean P Colgan
Swimming through the gut: implications of fluid transport on the microbiome.
Sean P Colgan; Stefan F Ehrentraut; Louise E Glover; Douglas J Kominsky; Eric L Campbell
Contributions of neutrophils to resolution of mucosal inflammation.
Sean P Colgan; Blair Fennimore; Stefan F Ehrentraut
Adenosine and gastrointestinal inflammation.

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All Publications

2013: Sean P Colgan
Swimming through the gut: implications of fluid transport on the microbiome.
Digestive diseases and sciences 2013;58(3):602-3.
2013: Sean P Colgan; Stefan F Ehrentraut; Louise E Glover; Douglas J Kominsky; Eric L Campbell
Contributions of neutrophils to resolution of mucosal inflammation.
Immunologic research 2013;55(1-3):75-82.
2013: Sean P Colgan; Blair Fennimore; Stefan F Ehrentraut
Adenosine and gastrointestinal inflammation.
Journal of molecular medicine (Berlin, Germany) 2013;91(2):157-64.
2013: Stefan F Ehrentraut; Louise E Glover; Caleb J Kelly; Douglas J Kominsky; Amanda J Bayless; Brittelle E Bowers; Eric L Campbell; Sean P Colgan
Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(1):392-400.
2012: Eric T Clambey; Sean P Colgan; Edwin F de Zoeten; Louise E Glover; Paul Jedlicka; Eóin N McNamee; Kurt R Stenmark; Joseph A Westrich; John C Cambier; Eric L Campbell; Holger K Eltzschig
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):E2784-93.
2012: Stefan F Ehrentraut; Sean P Colgan
Implications of protein post-translational modifications in IBD.
Inflammatory bowel diseases 2012;18(7):1378-88.
2012: Tobias Eckle; Stephanie Bonney; Christoph H Borchers; Peter M Buttrick; Sean P Colgan; Jun Han; Katherine Hartmann; Douglas J Kominsky; Brian D Lowes; Michel Mittelbronn; Susan Reithel; Lori A Walker; Holger K Eltzschig
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.
Nature medicine 2012;18(5):774-82.
2012: Caleb J Kelly; Sean P Colgan; Daniel N Frank
Of microbes and meals: the health consequences of dietary endotoxemia.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2012;27(2):215-25.
2012: Sean P Colgan; Holger K Eltzschig
Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery.
Annual review of physiology 2012;74():153-75.
2011: Eric L Campbell; Charles N Serhan; Sean P Colgan
Antimicrobial aspects of inflammatory resolution in the mucosa: a role for proresolving mediators.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3475-81.
2011: Jonathan I Goldstein; Nicole Jacobson; Douglas J Kominsky; Kirsten Regalia; Melinda Yousefi; Michael T Falta; Andrew P Fontenot; Mark E Gerich; Lucy Golden-Mason; Gregory L Austin; Brittelle Bowers; Sean P Colgan
Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease.
Gastroenterology 2011;141(1):208-16.
2011: Douglas J Kominsky; Simon Keely; Christopher F MacManus; Louise E Glover; Melanie Scully; Colm Collins; Brittelle E Bowers; Eric L Campbell; Sean P Colgan
An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6505-14.
2011: Louise E Glover; Sean P Colgan
Hypoxia and metabolic factors that influence inflammatory bowel disease pathogenesis.
Gastroenterology 2011;140(6):1748-55.
2011: Louise E Glover; Karina Irizarry; Melanie Scully; Eric L Campbell; Brittelle E Bowers; Carol M Aherne; Douglas J Kominsky; Christopher F MacManus; Sean P Colgan
IFN-γ attenuates hypoxia-inducible factor (HIF) activity in intestinal epithelial cells through transcriptional repression of HIF-1β.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(3):1790-8.
2011: Marilee J Wick; Erica J Buesing; Carol A Wehling; Zoe L Loomis; Carlyne D Cool; Martin R Zamora; York E Miller; Sean P Colgan; Louis B Hersh; Norbert F Voelkel; Edward C Dempsey
Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2011;183(3):330-40.
2010: Eric L Campbell; Christopher F MacManus; Douglas J Kominsky; Simon Keely; Louise E Glover; Brittelle E Bowers; Melanie Scully; Walter J Bruyninckx; Sean P Colgan
Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(32):14298-303.
2010: Sean P Colgan; Cormac T Taylor
Hypoxia: an alarm signal during intestinal inflammation.
Nature reviews. Gastroenterology & hepatology 2010;7(5):281-7.
2010: Douglas J Kominsky; Eric L Campbell; Sean P Colgan
Metabolic shifts in immunity and inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(8):4062-8.
2010: Simon Keely; Louise E Glover; Thomas Weissmueller; Christopher F MacManus; Sophie Fillon; Blair Fennimore; Sean P Colgan
Hypoxia-inducible factor-dependent regulation of platelet-activating factor receptor as a route for gram-positive bacterial translocation across epithelia.
Molecular biology of the cell 2010;21(4):538-46.
2009: Janek Henes; Marthe A Schmit; Julio C Morote-Garcia; Valbona Mirakaj; David Köhler; Louise Glover; Therese Eldh; Ulrich Walter; Jörn Karhausen; Sean P Colgan; Peter Rosenberger
Inflammation-associated repression of vasodilator-stimulated phosphoprotein (VASP) reduces alveolar-capillary barrier function during acute lung injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(12):4244-55.
2009: Holger K Eltzschig; Jesus Rivera-Nieves; Sean P Colgan
Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation.
Expert opinion on therapeutic targets 2009;13(11):1267-77.
2009: Qian Liu; Jing Li; Joseph Khoury; Sean P Colgan; Juan C Ibla
Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation.
The Journal of biological chemistry 2009;284(20):13686-95.
2009: Simon Keely; Louise E Glover; Christopher F MacManus; Eric L Campbell; Melanie M Scully; Glenn T Furuta; Sean P Colgan
Selective induction of integrin beta1 by hypoxia-inducible factor: implications for wound healing.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(5):1338-46.
2009: Simon Keely; Sinéad M Ryan; David M Haddleton; Adam Limer; Giuseppe Mantovani; Evelyn P Murphy; Sean P Colgan; David J Brayden
Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.
Journal of controlled release : official journal of the Controlled Release Society 2009;135(1):35-43.
2009: Sophie Fillon; Zachary D Robinson; Sean P Colgan; Glenn T Furuta
Epithelial function in eosinophilic gastrointestinal diseases.
Immunology and allergy clinics of North America 2009;29(1):171-8, xii-xiii.
2009: Holger K Eltzschig; David Köhler; Tobias Eckle; Tianqing Kong; Simon C Robson; Sean P Colgan
Central role of Sp1-regulated CD39 in hypoxia/ischemia protection.
Blood 2009;113(1):224-32.
2008: Thomas Weissmüller; Eric L Campbell; Peter Rosenberger; Melanie Scully; Paul L Beck; Glenn T Furuta; Sean P Colgan
PMNs facilitate translocation of platelets across human and mouse epithelium and together alter fluid homeostasis via epithelial cell-expressed ecto-NTPDases.
The Journal of clinical investigation 2008;118(11):3682-92.
2008: Holger K Eltzschig; Christopher F Macmanus; Sean P Colgan
Neutrophils as sources of extracellular nucleotides: functional consequences at the vascular interface.
Trends in cardiovascular medicine 2008;18(3):103-7.
2008: Nancy A Louis; Andreas M Robinson; Christopher F MacManus; Jörn Karhausen; Melanie Scully; Sean P Colgan
Control of IFN-alphaA by CD73: implications for mucosal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):4246-55.
2008: Andreas Robinson; Simon Keely; Jorn Karhausen; Mark E Gerich; Glenn T Furuta; Sean P Colgan
Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition.
Gastroenterology 2008;134(1):145-55.
2007: Eric L Campbell; Nancy A Louis; Sarah E Tomassetti; Geraldine Canny; Makoto Arita; Charles N Serhan; Sean P Colgan
Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3162-70.
2007: Tianqing Kong; Melanie Scully; C Simon Shelley; Sean P Colgan
Identification of Pur alpha as a new hypoxia response factor responsible for coordinated induction of the beta 2 integrin family.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1934-41.
2007: Peter Rosenberger; Joseph Khoury; Tianqing Kong; Thomas Weissmüller; Andreas M Robinson; Sean P Colgan
Identification of vasodilator-stimulated phosphoprotein (VASP) as an HIF-regulated tissue permeability factor during hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2613-21.
2007: Yee-Ping Sun; Sungwhan F Oh; Jasim Uddin; Rong Yang; Katherine Gotlinger; Eric Campbell; Sean P Colgan; Nicos A Petasis; Charles N Serhan
Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation.
The Journal of biological chemistry 2007;282(13):9323-34.
2007: Joseph Khoury; Juan C Ibla; Andrew S Neish; Sean P Colgan
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation.
The Journal of clinical investigation 2007;117(3):703-11.
2007: Nancy A Louis; Eric Campbell; Sean P Colgan
Model systems to investigate neutrophil adhesion and chemotaxis.
Methods in molecular biology (Clifton, N.J.) 2007;412():257-70.
2006: Nancy A Louis; Kathryn E Hamilton; Geraldine Canny; Laurie L Shekels; Samuel B Ho; Sean P Colgan
Selective induction of mucin-3 by hypoxia in intestinal epithelia.
Journal of cellular biochemistry 2006;99(6):1616-27.
2006: Holger K Eltzschig; Christian Karcher; Natalie Küper; Alice Mager; Simon C Robson; Rainer Schulz; Thomas Weissmüller; Kerstin Boengler; Tobias Eckle; Sean P Colgan
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function.
Circulation research 2006;99(10):1100-8.
2006: Tianqing Kong; Karen A Westerman; Marion Faigle; Holger K Eltzschig; Sean P Colgan
HIF-dependent induction of adenosine A2B receptor in hypoxia.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(13):2242-50.
2006: Holger K Eltzschig; Marion Faigle; Simone Knapp; Jorn Karhausen; Juan C Ibla; Peter Rosenberger; Kirsten C Odegard; Peter C Laussen; Linda F Thompson; Sean P Colgan
Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26.
Blood 2006;108(5):1602-10.
2006: Geraldine Canny; Radiana T Trifonova; David W Kindelberger; Sean P Colgan; Raina N Fichorova
Expression and function of bactericidal/permeability-increasing protein in human genital tract epithelial cells.
The Journal of infectious diseases 2006;194(4):498-502.
2006: Juan C Ibla; Joseph Khoury; Tianqing Kong; Andreas Robinson; Sean P Colgan
Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1.
American journal of physiology. Cell physiology 2006;291(2):C282-9.
2006: Sean P Colgan; Holger K Eltzschig; Tobias Eckle; Linda F Thompson
Physiological roles for ecto-5'-nucleotidase (CD73).
Purinergic signalling 2006;2(2):351-60.
2006: Geraldine Canny; Elke Cario; Andreas Lennartsson; Urban Gullberg; Ciara Brennan; Ofer Levy; Sean P Colgan
Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(3):G557-67.
2006: Charles N Serhan; Katherine Gotlinger; Song Hong; Yan Lu; Jeffrey Siegelman; Tamara Baer; Rong Yang; Sean P Colgan; Nicos A Petasis
Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1848-59.
2006: Nancy A Louis; Dionne Daniels; Sean P Colgan
Cell-cell interactions on solid matrices.
Methods in molecular biology (Clifton, N.J.) 2006;341():51-9.
2005: Holger K Eltzschig; Parween Abdulla; Edgar Hoffman; Kathryn E Hamilton; Dionne Daniels; Caroline Schönfeld; Michaela Löffler; German Reyes; Michael Duszenko; Jorn Karhausen; Andreas Robinson; Karen A Westerman; Imogen R Coe; Sean P Colgan
HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia.
The Journal of experimental medicine 2005;202(11):1493-505.
2005: Thomas Weissmuller; Holger K Eltzschig; Sean P Colgan
Dynamic purine signaling and metabolism during neutrophil-endothelial interactions.
Purinergic signalling 2005;1(3):229-39.
2005: Nancy A Louis; Kathryn E Hamilton; Sean P Colgan
Lipid mediator networks and leukocyte transmigration.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(3-4):197-202.
2005: Jorn Karhausen; Tianqing Kong; Sailaja Narravula; Sean P Colgan
Induction of the von Hippel-Lindau tumor suppressor gene by late hypoxia limits HIF-1 expression.
Journal of cellular biochemistry 2005;95(6):1264-75.
2005: Nancy A Louis; Kathryn E Hamilton; Tianqing Kong; Sean P Colgan
HIF-dependent induction of apical CD55 coordinates epithelial clearance of neutrophils.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):950-9.
2005: Richard S Blumberg; Richard S Pitman; Cormac T Taylor; Sean P Colgan
Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(4):209-19.
2005: Geraldine Canny; Sean P Colgan
Events at the host-microbial interface of the gastrointestinal tract. I. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G593-7.
2005: Jorn Karhausen; Volker H Haase; Sean P Colgan
Inflammatory hypoxia: role of hypoxia-inducible factor.
Cell cycle (Georgetown, Tex.) 2005;4(2):256-8.
2004: Holger K Eltzschig; Linda F Thompson; Jorn Karhausen; Richard J Cotta; Juan C Ibla; Simon C Robson; Sean P Colgan
Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism.
Blood 2004;104(13):3986-92.
2004: Linda F Thompson; Holger K Eltzschig; Juan C Ibla; C Justin Van De Wiele; Regina Resta; Julio C Morote-Garcia; Sean P Colgan
Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.
The Journal of experimental medicine 2004;200(11):1395-405.
2004: Arthur Kaser; Edward E S Nieuwenhuis; Warren Strober; Lloyd Mayer; Ivan J Fuss; Sean P Colgan; Richard S Blumberg
Natural killer T cells in mucosal homeostasis.
Annals of the New York Academy of Sciences 2004;1029():154-68.
2004: Jorn Karhausen; Glenn T Furuta; John E Tomaszewski; Randall S Johnson; Sean P Colgan; Volker H Haase
Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.
The Journal of clinical investigation 2004;114(8):1098-106.
2004: Tianqing Kong; Holger K Eltzschig; Jorn Karhausen; Sean P Colgan; C Simon Shelley
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10440-5.
2004: Arthur Kaser; Edward E S Nieuwenhuis; Warren Strober; Ivan J Fuss; Sean P Colgan; Richard S Blumberg
CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface.
Journal of pediatric gastroenterology and nutrition 2004;39 Suppl 3():S719-22.
2004: Suzana Brozovic; Takashi Nagaishi; Masaru Yoshida; Stephanie Betz; Azucena Salas; Daohong Chen; Arthur Kaser; Jonathan N Glickman; Timothy Kuo; Alicia Little; Jamin Morrison; Nadia Corazza; Jin Yong Kim; Sean P Colgan; Stephen G Young; Mark A Exley; Richard S Blumberg
CD1d function is regulated by microsomal triglyceride transfer protein.
Nature medicine 2004;10(5):535-9.
2004: Karsten Gronert; Alpdogan Kantarci; Bruce D Levy; Clary B Clish; Sabine Odparlik; Hatice Hasturk; John A Badwey; Sean P Colgan; Thomas E Van Dyke; Charles N Serhan
A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(3):1856-61.
2004: Katrina M Comerford; Sean P Colgan
Assessing oxygen sensitivity of the multidrug resistance (MDR) gene.
Methods in enzymology 2004;381():376-87.
2003: Charles N Serhan; Ashish Jain; Sylvie Marleau; Clary B Clish; Alpdogan Kantarci; Balsam Behbehani; Sean P Colgan; Gregory L Stahl; Aksam J Merched; Nicos A Petasis; Lawrence Chan; Thomas E Van Dyke
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6856-65.
2003: Donald Lawrence; Walter J Bruyninckx; Nancy A Louis; Douglas M Lublin; Gregory L Stahl; Charles A Parkos; Sean P Colgan
Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia.
The Journal of experimental medicine 2003;198(7):999-1010.
2003: Sean P Colgan; Richard S Pitman; Takashi Nagaishi; Atsushi Mizoguchi; Emiko Mizoguchi; Lloyd F Mayer; Ling Shao; Ryan Sartor; John R Subjeck; Richard S Blumberg
Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells.
The Journal of clinical investigation 2003;112(5):745-54.
2003: Holger K Eltzschig; Juan C Ibla; Glenn T Furuta; Martin O Leonard; Kenneth Alan Jacobson; Keiichi Enjyoji; Simon C Robson; Sean P Colgan
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors.
The Journal of experimental medicine 2003;198(5):783-96.
2003: Ofer Levy; Geraldine Canny; Charles N Serhan; Sean P Colgan
Expression of BPI (bactericidal/permeability-increasing protein) in human mucosal epithelia.
Biochemical Society transactions 2003;31(Pt 4):795-800.
2003: Yvonne van de Wal; Nadia Corazza; Matthieu Allez; Lloyd F Mayer; Hideki Iijima; Mark Ryan; Steven Cornwall; Dominique Kaiserlian; Robert Hershberg; Yasuhiko Koezuka; Sean P Colgan; Richard S Blumberg
Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells.
Gastroenterology 2003;124(5):1420-31.
2003: Iolanda M Fierro; Sean P Colgan; Giovanni Bernasconi; Nicos A Petasis; Clary B Clish; Makoto Arita; Charles N Serhan
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit human neutrophil migration: comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2688-94.
2003: Katrina M Comerford; Martin O Leonard; Jorn Karhausen; Robyn Carey; Sean P Colgan; Cormac T Taylor
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):986-91.
2003: Jorn Karhausen; Juan C Ibla; Sean P Colgan
Implications of hypoxia on mucosal barrier function.
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(1):77-87.
2002: Arndt Schottelius; Claudia Giesen; Khusru Asadullah; Iolanda M Fierro; Sean P Colgan; John G Bauman; William J Guilford; H Daniel Perez; John Parkinson
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):7063-70.
2002: Charles N Serhan; Song Hong; Karsten Gronert; Sean P Colgan; Pallavi R Devchand; Gudrun Mirick; Rose-Laure Moussignac
Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals.
The Journal of experimental medicine 2002;196(8):1025-37.
2002: Kristin Synnestvedt; Glenn T Furuta; Katrina M Comerford; Nancy A Louis; Jorn Karhausen; Holger K Eltzschig; Karl R Hansen; Linda F Thompson; Sean P Colgan
Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia.
The Journal of clinical investigation 2002;110(7):993-1002.
2002: Katrina M Comerford; Timothy J Wallace; Jorn Karhausen; Nancy A Louis; Michael C Montalto; Sean P Colgan
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.
Cancer research 2002;62(12):3387-94.
2002: Edward E S Nieuwenhuis; Tetsuya Matsumoto; Mark A Exley; Robbert A Schleipman; Jonathan N Glickman; Dan T Bailey; Nadia Corazza; Sean P Colgan; Andrew B Onderdonk; Richard S Blumberg
CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung.
Nature medicine 2002;8(6):588-93.
2002: Donald Lawrence; Katrina M Comerford; Sean P Colgan
Role of VASP in reestablishment of epithelial tight junction assembly after Ca2+ switch.
American journal of physiology. Cell physiology 2002;282(6):C1235-45.
2002: Sean P Colgan
Lipid mediators in epithelial cell-cell interactions.
Cellular and molecular life sciences : CMLS 2002;59(5):754-60.
2002: Charles Collard; Kellie A Park; Michael C Montalto; Sailaja Alapati; Jon A Buras; Gregory L Stahl; Sean P Colgan
Neutrophil-derived glutamate regulates vascular endothelial barrier function.
The Journal of biological chemistry 2002;277(17):14801-11.
2002: Katrina M Comerford; Donald Lawrence; Kristin Synnestvedt; Boaz P Levi; Sean P Colgan
Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):583-5.
2002: Geraldine Canny; Ofer Levy; Glenn T Furuta; Sailaja Narravula-Alipati; Richard B Sisson; Charles N Serhan; Sean P Colgan
Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3902-7.
2002: Sean P Colgan; Katrina M Comerford; Donald Lawrence
Epithelial cell-neutrophil interactions in the alimentary tract: a complex dialog in mucosal surveillance and inflammation.
TheScientificWorldJournal 2002;2():76-88.
2002: Sean P Colgan; Cormac T Taylor; Sailaja Narravula; Kristin Synnestvedt; Elizabeth D Blume
Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue.
Advances in experimental medicine and biology 2002;507():107-12.
2002: Stephan Brand; Takanori Sakaguchi; Xiubin Gu; Sean P Colgan; Hans-Christian Reinecker
Fractalkine-mediated signals regulate cell-survival and immune-modulatory responses in intestinal epithelial cells.
Gastroenterology 2002;122(1):166-77.
2001: Sailaja Narravula; Sean P Colgan
Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7543-8.
2001: Richard S Blumberg; Y van de Wal; Steven Claypool; Nadia Corazza; Bonny L Dickinson; Edward E S Nieuwenhuis; R Pitman; Gerburg M Spiekermann; Xiaoping Zhu; Sean P Colgan; Wayne I Lencer
The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function.
Acta odontologica Scandinavica 2001;59(3):139-44.
2001: W J Bruyninckx; Katrina M Comerford; Donald Lawrence; Sean P Colgan
Phosphoinositide 3-kinase modulation of beta(3)-integrin represents an endogenous "braking" mechanism during neutrophil transmatrix migration.
Blood 2001;97(10):3251-8.
2001: Glenn T Furuta; Jerrold R Turner; Cormac T Taylor; Robert Hershberg; Katrina M Comerford; Sailaja Narravula; D K Podolsky; Sean P Colgan
Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia.
The Journal of experimental medicine 2001;193(9):1027-34.
2000: Charles N Serhan; Clary B Clish; J Brannon; Sean P Colgan; Karsten Gronert; Nan Chiang
Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2000;51(4 Pt 1):643-54.
2000: Sailaja Narravula; PF Lennon; Beatrice U Mueller; Sean P Colgan
Regulation of endothelial CD73 by adenosine: paracrine pathway for enhanced endothelial barrier function.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5262-8.
2000: Cormac T Taylor; Glenn T Furuta; Kristin Synnestvedt; Sean P Colgan
Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12091-6.
2000: Charles N Serhan; Clary B Clish; J Brannon; Sean P Colgan; Nan Chiang; Karsten Gronert
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
The Journal of experimental medicine 2000;192(8):1197-204.
2000: Hyun Sil Kim; Sean P Colgan; R Pitman; Robert Hershberg; Richard S Blumberg
Human CD1d associates with prolyl-4-hydroxylase during its biosynthesis.
Molecular immunology 2000;37(14):861-8.
2000: Glenn T Furuta; AL Dzus; Cormac T Taylor; Sean P Colgan
Parallel induction of epithelial surface-associated chemokine and proteoglycan by cellular hypoxia: implications for neutrophil activation.
Journal of leukocyte biology 2000;68(2):251-9.
1999: Sean P Colgan; Robert Hershberg; Glenn T Furuta; Richard S Blumberg
Ligation of intestinal epithelial CD1d induces bioactive IL-10: critical role of the cytoplasmic tail in autocrine signaling.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13938-43.
1999: Cormac T Taylor; Sean P Colgan
Therapeutic targets for hypoxia-elicited pathways.
Pharmaceutical research 1999;16(10):1498-505.
1999: Cormac T Taylor; N Fueki; A Agah; Robert Hershberg; Sean P Colgan
Critical role of cAMP response element binding protein expression in hypoxia-elicited induction of epithelial tumor necrosis factor-alpha.
The Journal of biological chemistry 1999;274(27):19447-54.
1999: Richard S Blumberg; Wayne I Lencer; Xiaoping Zhu; H S Kim; Steven Claypool; Steven P Balk; Lawrence J Saubermann; Sean P Colgan
Antigen presentation by intestinal epithelial cells.
Immunology letters 1999;69(1):7-11.
1999: K Somnay-Wadgaonkar; Asma Nusrat; H S Kim; W P Canchis; Steven P Balk; Sean P Colgan; Richard S Blumberg
Immunolocalization of CD1d in human intestinal epithelial cells and identification of a beta2-microglobulin-associated form.
International immunology 1999;11(3):383-92.
1999: Charles Collard; C Bukusoglu; A Agah; Sean P Colgan; Wende R Reenstra; B P Morgan; Gregory L Stahl
Hypoxia-induced expression of complement receptor type 1 (CR1, CD35) in human vascular endothelial cells.
The American journal of physiology 1999;276(2 Pt 1):C450-8.
1998: PF Lennon; Cormac T Taylor; Gregory L Stahl; Sean P Colgan
Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation.
The Journal of experimental medicine 1998;188(8):1433-43.
1998: E D Blume; Cormac T Taylor; PF Lennon; Gregory L Stahl; Sean P Colgan
Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue.
The Journal of clinical investigation 1998;102(6):1161-72.
1998: Karsten Gronert; Sean P Colgan; Charles N Serhan
Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation.
The Journal of pharmacology and experimental therapeutics 1998;285(1):252-61.
1998: JF Maddox; Sean P Colgan; Clary B Clish; Nicos A Petasis; Valery V Fokin; Charles N Serhan
Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(6):487-94.
1998: Cormac T Taylor; AL Dzus; Sean P Colgan
Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.
Gastroenterology 1998;114(4):657-68.
1998: C T Taylor; S J Lisco; C S Awtrey; Sean P Colgan
Hypoxia inhibits cyclic nucleotide-stimulated epithelial ion transport: role for nucleotide cyclases as oxygen sensors.
The Journal of pharmacology and experimental therapeutics 1998;284(2):568-75.
1997: G Zünd; S Uezono; Gregory L Stahl; AL Dzus; Francis X McGowan; Paul R Hickey; Sean P Colgan
Hypoxia enhances induction of endothelial ICAM-1: role for metabolic acidosis and proteasomes.
The American journal of physiology 1997;273(5 Pt 1):C1571-80.
1997: A D Christ; Sean P Colgan; Steven P Balk; Richard S Blumberg
Human intestinal epithelial cell lines produce factor(s) that inhibit CD3-mediated T-lymphocyte proliferation.
Immunology letters 1997;58(3):159-65.
1997: Charles Collard; A Väkevä; C Büküsoglu; G Zünd; C SPERATI; Sean P Colgan; Gregory L Stahl
Reoxygenation of hypoxic human umbilical vein endothelial cells activates the classic complement pathway.
Circulation 1997;96(1):326-33.
1996: Sean P Colgan; AL Dzus; Charles A Parkos
Epithelial exposure to hypoxia modulates neutrophil transepithelial migration.
The Journal of experimental medicine 1996;184(3):1003-15.
1996: G Zünd; David P Nelson; Ellis J Neufeld; AL Dzus; J Bischoff; John E Mayer; Sean P Colgan
Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7075-80.
1996: Charles A Parkos; Sean P Colgan; M S Diamond; Asma Nusrat; Tony Liang; Timothy A Springer; James L Madara
Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/CD18-mediated interactions with neutrophils.
Molecular medicine (Cambridge, Mass.) 1996;2(4):489-505.
1996: P Hofman; L D'Andrea; D Carnes; Sean P Colgan; James L Madara
Intestinal epithelial cytoskeleton selectively constrains lumen-to-tissue migration of neutrophils.
The American journal of physiology 1996;271(1 Pt 1):C312-20.
1996: Sean P Colgan; Victor Morales; James L Madara; J E Polischuk; S P Balk; Richard S Blumberg
IFN-gamma modulates CD1d surface expression on intestinal epithelia.
The American journal of physiology 1996;271(1 Pt 1):C276-83.
1996: G Zünd; James L Madara; AL Dzus; C S Awtrey; Sean P Colgan
Interleukin-4 and interleukin-13 differentially regulate epithelial chloride secretion.
The Journal of biological chemistry 1996;271(13):7460-4.
1996: Charles A Parkos; Sean P Colgan; Tony Liang; Asma Nusrat; A E Bacarra; D K Carnes; James L Madara
CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia.
The Journal of cell biology 1996;132(3):437-50.
1996: G Zünd; AL Dzus; D K McGuirk; C Breuer; T Shinoka; John E Mayer; Sean P Colgan
Hypoxic stress alone does not modulate endothelial surface expression of bovine E-selectin and intercellular adhesion molecule-1 (ICAM-1).
Swiss surgery. Supplement 1996;Suppl 1():41-5.
1995: Charles N Serhan; J F Maddox; Nicos A Petasis; I Akritopoulou-Zanze; A Papayianni; Hugh R Brady; Sean P Colgan; James L Madara
Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils.
Biochemistry 1995;34(44):14609-15.
1995: Asma Nusrat; M Giry; Jerrold R Turner; Sean P Colgan; Charles A Parkos; D Carnes; emmanuel lemichez; Patrice Boquet; James L Madara
Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10629-33.
1995: Sean P Colgan; Charles A Parkos; D McGuirk; Hugh R Brady; A A Papayianni; G Frendl; James L Madara
Receptors involved in carbohydrate binding modulate intestinal epithelial-neutrophil interactions.
The Journal of biological chemistry 1995;270(18):10531-9.
1995: M B Resnick; Sean P Colgan; Charles A Parkos; C Delp-Archer; D McGuirk; Peter Weller; James L Madara
Human eosinophils migrate across an intestinal epithelium in response to platelet-activating factor.
Gastroenterology 1995;108(2):409-16.
1995: Charles A Parkos; Sean P Colgan; A E Bacarra; Asma Nusrat; C Delp-Archer; S Carlson; D H Su; James L Madara
Intestinal epithelia (T84) possess basolateral ligands for CD11b/CD18-mediated neutrophil adherence.
The American journal of physiology 1995;268(2 Pt 1):C472-9.
1995: S E Sanders; James L Madara; D K McGuirk; D S Gelman; Sean P Colgan
Assessment of inflammatory events in epithelial permeability: a rapid screening method using fluorescein dextrans.
Epithelial cell biology 1995;4(1):25-34.
1994: Sean P Colgan; M B Resnick; Charles A Parkos; C Delp-Archer; D McGuirk; A E Bacarra; Peter Weller; James L Madara
IL-4 directly modulates function of a model human intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(5):2122-9.
1994: Sean P Colgan; Charles A Parkos; Jeffrey B Matthews; L D'Andrea; C S Awtrey; A H Lichtman; C Delp-Archer; James L Madara
Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells.
The American journal of physiology 1994;267(2 Pt 1):C402-10.
1994: P Kaoutzani; Sean P Colgan; K L Cepek; P G Burkard; S Carlson; C Delp-Archer; Michael B Brenner; James L Madara
Reconstitution of cultured intestinal epithelial monolayers with a mucosal-derived T lymphocyte cell line. Modulation of epithelial phenotype dependent on lymphocyte-basolateral membrane apposition.
The Journal of clinical investigation 1994;94(2):788-96.
1994: Charles A Parkos; Sean P Colgan; J L Madara
Interactions of neutrophils with epithelial cells: lessons from the intestine.
Journal of the American Society of Nephrology : JASN 1994;5(2):138-52.
1994: S P Balk; S Burke; J E Polischuk; M E Frantz; L Yang; Steven A Porcelli; Sean P Colgan; Richard S Blumberg
Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium.
Science (New York, N.Y.) 1994;265(5169):259-62.
1993: M B Resnick; Sean P Colgan; Thomas Patapoff; Randall J Mrsny; C S Awtrey; C Delp-Archer; Peter Weller; James L Madara
Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(10):5716-23.
1993: Beth A McCormick; Sean P Colgan; C Delp-Archer; S I Miller; James L Madara
Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.
The Journal of cell biology 1993;123(4):895-907.
1993: Sean P Colgan; Charles N Serhan; Charles A Parkos; C Delp-Archer; James L Madara
Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers.
The Journal of clinical investigation 1993;92(1):75-82.
1993: James L Madara; Thomas Patapoff; B Gillece-Castro; Sean P Colgan; Charles A Parkos; C Delp; Randall J Mrsny
5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.
The Journal of clinical investigation 1993;91(5):2320-5.
1993: Sean P Colgan; Charles A Parkos; C Delp; M A Arnaout; James L Madara
Neutrophil migration across cultured intestinal epithelial monolayers is modulated by epithelial exposure to IFN-gamma in a highly polarized fashion.
The Journal of cell biology 1993;120(3):785-98.
1992: Sean P Colgan; Jeffrey B Matthews; Charles A Parkos; C Delp; C S Awtrey; James L Madara
The myeloid leukemia cell line HL-60 produces a factor that induces chloride secretion in cultured epithelial cells.
Journal of leukocyte biology 1992;52(2):183-7.
1992: James L Madara; Charles A Parkos; Sean P Colgan; R J MacLeod; S Nash; J Matthews; C Delp; Wayne I Lencer
Cl- secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue.
The Journal of clinical investigation 1992;89(6):1938-44.
1992: Charles A Parkos; Sean P Colgan; C Delp; M A Arnaout; James L Madara
Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways.
The Journal of cell biology 1992;117(4):757-64.
1992: James L Madara; Charles A Parkos; Sean P Colgan; Asma Nusrat; K Atisook; P Kaoutzani
The movement of solutes and cells across tight junctions.
Annals of the New York Academy of Sciences 1992;664():47-60.