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John Collard

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
29
van der Kammen, Rob
14
Michiels, Frits
10
ten Klooster, Jean Paul
8
Stam, Jord
7
Malliri, Angeliki
6
Mertens, Alexander
6
Roos, Ed
6
van Delft, S
5
Van Leeuwen, Frank
5
Sander, EE
5
Hordijk, Peter
4
Evers, Eva
4
Price, Leo
4
Rygiel, Tomasz
4
Strumane, Kristin

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Publications

TOP 3
Hajdo-Milasinovic Amra; van der Kammen Rob A; Moneva Zvezdana; Collard John G
Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling.
Gérard Audrey; van der Kammen Rob A; Janssen Hans; Ellenbroek Saskia I; Collard John G
The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
Strumane K; Rygiel T; van der Valk M; Collard J G
Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.

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All Publications

2009: Hajdo-Milasinovic Amra; van der Kammen Rob A; Moneva Zvezdana; Collard John G
Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling.
Journal of cell science 2009;122(Pt 12):2127-36.
2009: Gérard Audrey; van der Kammen Rob A; Janssen Hans; Ellenbroek Saskia I; Collard John G
The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
Blood 2009;113(24):6138-47.
2009: Strumane K; Rygiel T; van der Valk M; Collard J G
Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.
Journal of cancer research and clinical oncology 2009;135(1):69-80.
2008: Iden Sandra; Collard John G
Crosstalk between small GTPases and polarity proteins in cell polarization.
Nature reviews. Molecular cell biology 2008;9(11):846-59.
2008: Rygiel Tomasz P; Mertens Alexander E; Strumane Kristin; van der Kammen Rob; Collard John G
The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.
Journal of cell science 2008;121(Pt 8):1183-92.
2008: Strumane Kristin; Song Ji-Ying; Baas Inge; Collard John G
Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency.
Leukemia research 2008;32(1):113-20.
2007: Pegtel D Michiel; Ellenbroek Saskia I J; Mertens Alexander E E; van der Kammen Rob A; de Rooij Johan; Collard John G
The Par-Tiam1 complex controls persistent migration by stabilizing microtubule-dependent front-rear polarity.
Current biology : CB 2007;17(19):1623-34.
2007: Gérard Audrey; Mertens Alexander E E; van der Kammen Rob A; Collard John G
The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization.
The Journal of cell biology 2007;176(6):863-75.
2007: Hajdo-Milasinovic Amra; Ellenbroek Saskia I J; van Es Saskia; van der Vaart Babet; Collard John G
Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.
Journal of cell science 2007;120(Pt 4):555-66.
2007: Ellenbroek Saskia I J; Collard John G
Rho GTPases: functions and association with cancer.
Clinical & experimental metastasis 2007;24(8):657-72.
2006: Engers R; Mueller M; Walter A; Collard J G; Willers R; Gabbert H E
Prognostic relevance of Tiam1 protein expression in prostate carcinomas.
British journal of cancer 2006;95(8):1081-6.
2006: Ten Klooster Jean Paul; Evers Eva E; Janssen Lennert; Machesky Laura M; Michiels Frits; Hordijk Peter; Collard John G
Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
The Biochemical journal 2006;397(1):39-45.
2006: Mertens Alexander E E; Pegtel D Michiel; Collard John G
Tiam1 takes PARt in cell polarity.
Trends in cell biology 2006;16(6):308-16.
2006: Malliri Angeliki; Rygiel Tomasz P; van der Kammen Rob A; Song Ji-Ying; Engers Rainer; Hurlstone Adam F L; Clevers Hans; Collard John G
The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.
The Journal of biological chemistry 2006;281(1):543-8.
2006: Strumane Kristin; Rygiel Tomasz P; Collard John G
The Rac activator Tiam1 and Ras-induced oncogenesis.
Methods in enzymology 2006;407():269-81.
2005: Hamelers Irene H L; Olivo Cristina; Mertens Alexander E E; Pegtel D Michiel; van der Kammen Rob A; Sonnenberg Arnoud; Collard John G
The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.
The Journal of cell biology 2005;171(5):871-81.
2005: Mertens Alexander E E; Rygiel Tomasz P; Olivo Cristina; van der Kammen Rob; Collard John G
The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex.
The Journal of cell biology 2005;170(7):1029-37.
2004: Uhlenbrock Katharina; Eberth Alexander; Herbrand Ulrike; Daryab Neda; Stege Patricia; Meier Friedegund; Friedl Peter; Collard John G; Ahmadian Mohammad Reza
The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism.
Journal of cell science 2004;117(Pt 20):4863-71.
2004: Price Leo S; Hajdo-Milasinovic Amra; Zhao Jun; Zwartkruis Fried J T; Collard John G; Bos Johannes L
Rap1 regulates E-cadherin-mediated cell-cell adhesion.
The Journal of biological chemistry 2004;279(34):35127-32.
2004: Malliri Angeliki; van Es Saskia; Huveneers Stephan; Collard John G
The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions.
The Journal of biological chemistry 2004;279(29):30092-8.
2004: Zimmerman Aukje W; Nelissen Judith M D T; van Emst-de Vries Sjenet E; Willems Peter H G M; de Lange Frank; Collard John G; van Leeuwen Frank N; Figdor Carl G
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.
Journal of cell science 2004;117(Pt 13):2841-52.
2004: Honing Henk; van den Berg Timo K; van der Pol Susanne M A; Dijkstra Christine D; van der Kammen Rob A; Collard John G; de Vries Helga E
RhoA activation promotes transendothelial migration of monocytes via ROCK.
Journal of leukocyte biology 2004;75(3):523-8.
2003: Malliri Angeliki; Collard John G
Role of Rho-family proteins in cell adhesion and cancer.
Current opinion in cell biology 2003;15(5):583-9.
2003: Price Leo S; Langeslag Michiel; ten Klooster Jean Paul; Hordijk Peter L; Jalink Kees; Collard John G
Calcium signaling regulates translocation and activation of Rac.
The Journal of biological chemistry 2003;278(41):39413-21.
2003: Mertens Alexander E; Roovers Rob C; Collard John G
Regulation of Tiam1-Rac signalling.
FEBS letters 2003;546(1):11-6.
2003: Van Leeuwen Frank N; Olivo Cristina; Grivell Shula; Giepmans Ben N G; Collard John G; Moolenaar Wouter H
Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
The Journal of biological chemistry 2003;278(1):400-6.
2002: Driessens Mariette H E; Olivo Cristina; Nagata Koh-ichi; Inagaki Masaki; Collard John G
B plexins activate Rho through PDZ-RhoGEF.
FEBS letters 2002;529(2-3):168-72.
2002: Lambert John M; Lambert Que T; Reuther Gary W; Malliri Angeliki; Siderovski David P; Sondek John; Collard John G; Der Channing J
Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism.
Nature cell biology 2002;4(8):621-5.
2002: Malliri Angeliki; van der Kammen Rob A; Clark Kristopher; van der Valk Maarten; Michiels Frits; Collard John G
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Nature 2002;417(6891):867-71.
2002: van Wetering Sandra; van Buul Jaap D; Quik Safira; Mul Frederik P J; Anthony Eloise C; ten Klooster Jean-Paul; Collard John G; Hordijk Peter L
Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells.
Journal of cell science 2002;115(Pt 9):1837-46.
2002: Malliri Angeliki; ten Klooster Jean P; Olivio Christina; Collard John G
Determination of the activity of Rho-like GTPases in cells.
Methods in molecular biology (Clifton, N.J.) 2002;189():99-109.
2001: Engers R; Springer E; Michiels F; Collard J G; Gabbert H E
Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.
The Journal of biological chemistry 2001;276(45):41889-97.
2001: Price L S; Collard J G
Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion.
Seminars in cancer biology 2001;11(2):167-73.
2000: van Nieuw Amerongen G P; van Delft S; Vermeer M A; Collard J G; van Hinsbergh V W
Activation of RhoA by thrombin in endothelial hyperpermeability: role of Rho kinase and protein tyrosine kinases.
Circulation research 2000;87(4):335-40.
2000: Evers E E; Zondag G C; Malliri A; Price L S; ten Klooster J P; van der Kammen R A; Collard J G
Rho family proteins in cell adhesion and cell migration.
European journal of cancer (Oxford, England : 1990) 2000;36(10):1269-74.
2000: Zondag G C; Evers E E; ten Klooster J P; Janssen L; van der Kammen R A; Collard J G
Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition.
The Journal of cell biology 2000;149(4):775-82.
2000: Evers E E; van der Kammen R A; ten Klooster J P; Collard J G
Rho-like GTPases in tumor cell invasion.
Methods in enzymology 2000;325():403-15.
2000: Michiels F; van der Kammen R A; Janssen L; Nolan G; Collard J G
Expression of Rho GTPases using retroviral vectors.
Methods in enzymology 2000;325():295-302.
1999: Sander E E; Collard J G
Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.
European journal of cancer (Oxford, England : 1990) 1999;35(14):1905-11.
1999: Gimond C; van Der Flier A; van Delft S; Brakebusch C; Kuikman I; Collard J G; Fässler R; Sonnenberg A
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
The Journal of cell biology 1999;147(6):1325-40.
1999: Sander E E; ten Klooster J P; van Delft S; van der Kammen R A; Collard J G
Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior.
The Journal of cell biology 1999;147(5):1009-22.
1999: Reid T; Bathoorn A; Ahmadian M R; Collard J G
Identification and characterization of hPEM-2, a guanine nucleotide exchange factor specific for Cdc42.
The Journal of biological chemistry 1999;274(47):33587-93.
1999: Sander E E; Collard J G
Rho-like GTPases: their role in epithelial cell-cell adhesion and invasion.
European journal of cancer (Oxford, England : 1990) 1999;35(9):1302-8.
1999: van Leeuwen F N; van Delft S; Kain H E; van der Kammen R A; Collard J G
Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading.
Nature cell biology 1999;1(4):242-8.
1999: Geijsen N; van Delft S; Raaijmakers J A; Lammers J W; Collard J G; Koenderman L; Coffer P J
Regulation of p21rac activation in human neutrophils.
Blood 1999;94(3):1121-30.
1999: Michiels F; Collard J G
Rho-like GTPases: their role in cell adhesion and invasion.
Biochemical Society symposium 1999;65():125-46.
1999: Stam J C; Collard J G
The DH protein family, exchange factors for Rho-like GTPases.
Progress in molecular and subcellular biology 1999;22():51-83.
1998: Sander E E; van Delft S; ten Klooster J P; Reid T; van der Kammen R A; Michiels F; Collard J G
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase.
The Journal of cell biology 1998;143(5):1385-98.
1998: Stam J C; Michiels F; van der Kammen R A; Moolenaar W H; Collard J G
Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.
The EMBO journal 1998;17(14):4066-74.
1997: Hordijk P L; ten Klooster J P; van der Kammen R A; Michiels F; Oomen L C; Collard J G
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling.
Science (New York, N.Y.) 1997;278(5342):1464-6.
1997: Stam J C; Sander E E; Michiels F; van Leeuwen F N; Kain H E; van der Kammen R A; Collard J G
Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain.
The Journal of biological chemistry 1997;272(45):28447-54.
1997: Leeuwen F N; Kain H E; Kammen R A; Michiels F; Kranenburg O W; Collard J G
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
The Journal of cell biology 1997;139(3):797-807.
1997: Michiels F; Stam J C; Hordijk P L; van der Kammen R A; Ruuls-Van Stalle L; Feltkamp C A; Collard J G
Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
The Journal of cell biology 1997;137(2):387-98.
1996: Collard J G; Habets G G; Michiels F; Stam J; van der Kammen R A; van Leeuwen F
Role of Tiam 1 in Rac-mediated signal transduction pathways.
Current topics in microbiology and immunology 1996;213 ( Pt 2)():253-65.
1995: van Leeuwen F N; van der Kammen R A; Habets G G; Collard J G
Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells.
Oncogene 1995;11(11):2215-21.
1995: Michiels F; Habets G G; Stam J C; van der Kammen R A; Collard J G
A role for Rac in Tiam1-induced membrane ruffling and invasion.
Nature 1995;375(6529):338-40.
1995: Habets G G; van der Kammen R A; Stam J C; Michiels F; Collard J G
Sequence of the human invasion-inducing TIAM1 gene, its conservation in evolution and its expression in tumor cell lines of different tissue origin.
Oncogene 1995;10(7):1371-6.
1995: Habets G G; van der Kammen R A; Jenkins N A; Gilbert D J; Copeland N G; Hagemeijer A; Collard J G
The invasion-inducing TIAM1 gene maps to human chromosome band 21q22 and mouse chromosome 16.
Cytogenetics and cell genetics 1995;70(1-2):48-51.
1994: Habets G G; Scholtes E H; Zuydgeest D; van der Kammen R A; Stam J C; Berns A; Collard J G
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.
Cell 1994;77(4):537-49.
1992: Habets G G; van der Kammen R A; Willemsen V; Balemans M; Wiegant J; Collard J G
Sublocalization of an invasion-inducing locus and other genes on human chromosome 7.
Cytogenetics and cell genetics 1992;60(3-4):200-5.
1990: Habets G G; van der Kammen R A; Scholtes E H; Collard J G
Induction of invasive and metastatic potential in mouse T-lymphoma cells (BW5147) by treatment with 5-azacytidine.
Clinical & experimental metastasis 1990;8(6):567-77.
1989: Collard J G; Habets G G; Vander Kammen R; Scholtes E; Stoopen G
Genetic analysis of T-lymphoma invasion and metastasis.
Pathologie-biologie 1989;37(9):1030-1.
1989: Collard J G; Habets G G; van der Kammen R; Scholtes E
Genetic basis of T-lymphoma invasion.
Invasion & metastasis 1989;9(6):379-90.
1988: la Rivière G; Schipper C A; Collard J G; Roos E
Invasiveness in hepatocyte and fibroblast monolayers and metastatic potential of T-cell hybridomas in mice.
Cancer research 1988;48(12):3405-10.
1988: Collard J G; Roos E; La Rivière G; Habets G G
Genetic analysis of invasion and metastasis.
Cancer surveys 1988;7(4):691-710.
1987: Collard J G; van de Poll M; Scheffer A; Roos E; Hopman A H; Geurts van Kessel A H; van Dongen J J
Location of genes involved in invasion and metastasis on human chromosome 7.
Cancer research 1987;47(24 Pt 1):6666-70.
1987: Collard J G; Schijven J F; Roos E
Invasive and metastatic potential induced by ras-transfection into mouse BW5147 T-lymphoma cells.
Cancer research 1987;47(3):754-9.
1986: Janssen J W; Collard J G; Tulp A; Cox D; Millington-Ward A; Pearson P
Construction and analysis of an EMBL-3 phage library containing partially digested human chromosome 21-specific DNA inserts (15-20 kb).
Cytometry 1986;7(5):411-7.
1986: Bolscher J G; Schallier D C; Smets L A; van Rooy H; Collard J G; Bruyneel E A; Mareel M M
Effect of cancer-related and drug-induced alterations in surface carbohydrates on the invasive capacity of mouse and rat cells.
Cancer research 1986;46(8):4080-6.
1986: Collard J G; Schijven J F; Bikker A; La Riviere G; Bolscher J G; Roos E
Cell surface sialic acid and the invasive and metastatic potential of T-cell hybridomas.
Cancer research 1986;46(7):3521-7.
1986: Janssen J W; Vernole P; de Boer P A; Oosterhuis J W; Collard J G
Sublocalization of c-myb to 6q21----q23 by in situ hybridization and c-myb expression in a human teratocarcinoma with 6q rearrangements.
Cytogenetics and cell genetics 1986;41(3):129-35.
1985: Roos E; La Rivière G; Collard J G; Stukart M J; De Baetselier P
Invasiveness of T-cell hybridomas in vitro and their metastatic potential in vivo.
Cancer research 1985;45(12 Pt 1):6238-43.
1985: Collard J G; de Boer P A; Janssen J W; Schijven J F; de Jong B
Gene mapping by chromosome spot hybridization.
Cytometry 1985;6(3):179-85.
1985: Collard J G; van Beek W P; Janssen J W; Schijven J F
Transfection by human oncogenes: concomitant induction of tumorigenicity and tumor-associated membrane alterations.
International journal of cancer. Journal international du cancer 1985;35(2):207-13.
1984: Collard J G; Philippus E; Tulp A; Lebo R V; Gray J W
Separation and analysis of human chromosomes by combined velocity sedimentation and flow sorting applying single- and dual-laser flow cytometry.
Cytometry 1984;5(1):9-19.
1982: Collard J G; Schijven J; Tulp A; Meulenbroek M
Localization of genes on fractionated rat chromosomes by molecular hybridization.
Experimental cell research 1982;137(2):463-9.
1982: Tulp A; Aten J A; Barnhoorn M G; van Beek W P; Collard J G; Lutter R; Westra J G
Separation of cells and cell organelles by weak physical forces IV. Applications.
Progress in clinical and biological research 1982;102 pt A():105-14.
1981: Collard J G; Tulp A; Stegeman J; Boezeman J
Separation of human metaphase chromosomes at neutral pH by velocity sedimentation at 20 times gravity.
Experimental cell research 1981;133(2):341-6.
1980: Collard J G; Tulp A; Stegeman J; Boezeman J; Bauer F W; Jongkind J F; Verkerk A
Separation of large quantities of Chinese hamster chromosomes by velocity sedimentation at unit gravity followed by blow sorting (FACS II).
Experimental cell research 1980;130(1):217-27.
1980: Tulp A; Collard J G; Hart A A; Aten J A
A new unit gravity sedimentation chamber.
Analytical biochemistry 1980;105(2):246-56.
1980: Collard J G; Tulp A; Hollander J H; Bauer F W; Boezeman J
Separation of large quantities of chromosomes by velocity sedimentation at unit gravity.
Experimental cell research 1980;126(1):191-7.

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