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William Colledge

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Colin J Stoneking; David Nicholson Thomas; William H Colledge; Oshini Shivakumar; Michael J Mason
Voltage dependence of the Ca2+-activated K+ channel KCa3.1 in human erythroleukemia cells.
William H Colledge; Joanne Doran; Hua Mei
Model systems for studying kisspeptin signalling: mice and cells.
Naresh kumar Hanchate; Danièle Mazur; Jyoti Parkash; Nicole Bellefontaine; William H Colledge; Xavier d'Anglemont de Tassigny; Xavier d'Anglemont de Tassigny
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.

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2013: Colin J Stoneking; David Nicholson Thomas; William H Colledge; Oshini Shivakumar; Michael J Mason
Voltage dependence of the Ca2+-activated K+ channel KCa3.1 in human erythroleukemia cells.
American journal of physiology. Cell physiology 2013;304(9):C858-72.
2013: William H Colledge; Joanne Doran; Hua Mei
Model systems for studying kisspeptin signalling: mice and cells.
Advances in experimental medicine and biology 2013;784():481-503.
2012: Naresh kumar Hanchate; Danièle Mazur; Jyoti Parkash; Nicole Bellefontaine; William H Colledge; Xavier d'Anglemont de Tassigny; Xavier d'Anglemont de Tassigny
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(3):932-45.
2011: Marco Musumeci; Paola Sestili; Michele Signore; Tonino Stati; Caterina Ambrosio; Liviana Catalano; William H Colledge; Andrew A Grace; Sonia Maccari; Paola Molinari; Giuseppe Marano
Propranolol enhances cell cycle-related gene expression in pressure overloaded hearts.
British journal of pharmacology 2011;164(8):1917-28.
2011: Hua Mei; Cara Walters; Richard Carter; William H Colledge
Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens.
Reproduction (Cambridge, England) 2011;141(3):357-66.
2011: Janet J Maguire; Emma J Mead; William H Colledge; Xavier d'Anglemont de Tassigny; Helen R Kirby; Rhoda E Kuc; Anthony P Davenport
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor.
PloS one 2011;6(11):e27601.
2010: William H Colledge; Hua Mei; Xavier d'Anglemont de Tassigny
Mouse models to study the central regulation of puberty.
Molecular and cellular endocrinology 2010;324(1-2):12-20.
2010: Xavier d'Anglemont de Tassigny; Karen J Ackroyd; Emmanouella E Chatzidaki; William H Colledge
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(25):8581-90.
2010: William H Colledge; X d'Anglemont de Tassigny
The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice.
Annales d'endocrinologie 2010;71(3):198-200.
2010: Helen Waller-Evans; Simone Prömel; Tobias Langenhan; Dixon John; Dirk Zahn; William H Colledge; Joanne Doran; Mark B L Carlton; Ben Davies; Samuel A J R Aparicio; Johannes Grosse; Andreas P Russ
The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse.
PloS one 2010;5(11):e14047.
2009: William H Colledge
Kisspeptins and GnRH neuronal signalling.
Trends in endocrinology and metabolism: TEM 2009;20(3):115-21.
2008: Catharine Goddard; N S Ghais; Y Zhang; A J Williams; William H Colledge; Andrew A Grace; C L-H Huang
Physiological consequences of the P2328S mutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts.
Acta physiologica (Oxford, England) 2008;194(2):123-40.
2008: Xavier d'Anglemont de Tassigny; Lisa A Fagg; Mark B L Carlton; William H Colledge
Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals.
Endocrinology 2008;149(8):3926-32.
2008: Adele R Gordon; Susan V Outram; Mohammad Keramatipour; Catharine Goddard; William H Colledge; James C Metcalfe; Ariadne Loukia Hager-Theodorides; Tessa Crompton; Paul R Kemp
Splenomegaly and modified erythropoiesis in KLF13-/- mice.
The Journal of biological chemistry 2008;283(18):11897-904.
2008: Jenna L Cash; Rosie Hart; Andreas Russ; Dixon John; William H Colledge; Joanne Doran; Alan G Hendrick; Mark B L Carlton; David Greaves
Synthetic chemerin-derived peptides suppress inflammation through ChemR23.
The Journal of experimental medicine 2008;205(4):767-75.
2008: Paul A Shaw; Ian R Catchpole; Catharine Goddard; William H Colledge
Comparison of protein transduction domains in mediating cell delivery of a secreted CRE protein.
Biochemistry 2008;47(4):1157-66.
2008: William H Colledge
GPR54 and kisspeptins.
Results and problems in cell differentiation 2008;46():117-43.
2007: Xavier d'Anglemont de Tassigny; Lisa A Fagg; Dixon John; Kate Day; Harry G Leitch; Alan G Hendrick; Dirk Zahn; Isabelle Franceschini; Alain Caraty; Mark B L Carlton; Samuel A J R Aparicio; William H Colledge
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10714-9.
2007: Kate S Stokoe; Richard Balasubramaniam; Catharine Goddard; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.
The Journal of physiology 2007;581(Pt 1):255-75.
2007: Matthew Killeen; Glyn Thomas; Iman S Gurung; Catharine Goddard; James A Fraser; Martyn P Mahaut-Smith; William H Colledge; Andrew A Grace; C L-H Huang
Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart.
Acta physiologica (Oxford, England) 2007;189(1):33-46.
2007: Glyn Thomas; Iman S Gurung; Matthew Killeen; Parvez Hakim; Catharine Goddard; Martyn P Mahaut-Smith; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.
The Journal of physiology 2007;578(Pt 1):85-97.
2007: Kate S Stokoe; Glyn Thomas; Catharine Goddard; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.
The Journal of physiology 2007;578(Pt 1):69-84.
2005: Catherine E Head; Richard Balasubramaniam; Glyn Thomas; Catharine Goddard; Ming Lei; William H Colledge; Andrew A Grace; Christopher L-H Huang
Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice.
Journal of cardiovascular electrophysiology 2005;16(12):1329-40.
2005: Toon A B van Veen; Mera Stein; Anne Royer; Khai Le Quang; Flavien Charpentier; William H Colledge; Christopher L-H Huang; Ronald Wilders; Andrew A Grace; Denis Escande; Jacques M T de Bakker; Harold V M van Rijen
Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging.
Circulation 2005;112(13):1927-35.
2005: Ming Lei; Catharine Goddard; Jie Liu; Anne-Laure Léoni; Anne Royer; Simon S-M Fung; Guosheng Xiao; Aiqun Ma; Henggui Zhang; Flavien Charpentier; Jamie I Vandenberg; William H Colledge; Andrew A Grace; Christopher L-H Huang
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a.
The Journal of physiology 2005;567(Pt 2):387-400.
2005: Gema Medina-Gomez; Sam Virtue; Christopher J Lelliott; Romina Boiani; Mark Campbell; Constantinos Christodoulides; Christophe Perrin; Mercedes Jimenez-Linan; Margaret Blount; Dixon John; Dirk Zahn; Rosemary R Thresher; Samuel A J R Aparicio; Mark Carlton; William H Colledge; Mikko I Kettunen; Tuulikki Seppänen-Laakso; Jaswinder Sethi; Stephen O'Rahilly; Kevin M Brindle; Saverio Cinti; Matej Oresic; Rémy Burcelin; Antonio Vidal-Puig
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.
Diabetes 2005;54(6):1706-16.
2005: John W Wiseman; Emily S Scott; Paul A Shaw; William H Colledge
Enhancement of gene delivery to human airway epithelial cells in vitro using a peptide from the polyoma virus protein VP1.
The journal of gene medicine 2005;7(6):759-70.
2005: Anne Royer; Toon A B van Veen; Sabrina Le Bouter; Céline Marionneau; Violaine Griol-Charhbili; Anne-Laure Léoni; Marja Steenman; Harold V M van Rijen; Sophie Demolombe; Catharine Goddard; Christine Richer; Brigitte Escoubet; Thérèse Jarry-Guichard; William H Colledge; Daniel Gros; Jacques M T de Bakker; Andrew A Grace; Denis Escande; Flavien Charpentier
Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis.
Circulation 2005;111(14):1738-46.
2005: Sophie Messager; Emmanouella E Chatzidaki; Dan Ma; Alan G Hendrick; Dirk Zahn; Dixon John; Rosemary R Thresher; Isabelle Malinge; Didier Lomet; Mark B L Carlton; William H Colledge; Alain Caraty; Samuel A J R Aparicio
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1761-6.
2004: William H Colledge
GPR54 and puberty.
Trends in endocrinology and metabolism: TEM 2004;15(9):448-53.
2004: Carsten Müller-Tidow; Ping Ji; Sven Diederichs; Jenny Potratz; Nicole Bäumer; Gabriele Köhler; Thomas Cauvet; Chunaram Choudary; Tiffany van der Meer; Wan-Yu Iris Chan; Conrad Nieduszynski; William H Colledge; Mary Carrington; H Phillip Koeffler; Anja Restle; Lisa Wiesmüller; Joëlle Sobczak-Thépot; Wolfgang E Berdel; Hubert Serve
The cyclin A1-CDK2 complex regulates DNA double-strand break repair.
Molecular and cellular biology 2004;24(20):8917-28.
2004: Shirin S Joseph; William H Colledge; Alberto J Kaumann
Aspartate138 is required for the high-affinity ligand binding site but not for the low-affinity binding site of the beta1-adrenoceptor.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(3):223-6.
2004: H D Nickerson; William H Colledge
A LacZ-based transgenic mouse for detection of somatic gene repair events in vivo.
Gene therapy 2004;11(17):1351-7.
2004: Shirin S Joseph; James A Lynham; William H Colledge; Alberto J Kaumann
Binding of (-)-[3H]-CGP12177 at two sites in recombinant human beta 1-adrenoceptors and interaction with beta-blockers.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(5):525-32.
2004: Shirin S Joseph; James A Lynham; Andrew A Grace; William H Colledge; Alberto J Kaumann
Markedly reduced effects of (-)-isoprenaline but not of (-)-CGP12177 and unchanged affinity of beta-blockers at Gly389-beta1-adrenoceptors compared to Arg389-beta1-adrenoceptors.
British journal of pharmacology 2004;142(1):51-6.
2004: Tiffany van der Meer; Wan Y I Chan; Luis S Palazon; Conrad Nieduszynski; Martin Murphy; Joëlle Sobczak-Thépot; Mary Carrington; William H Colledge
Cyclin A1 protein shows haplo-insufficiency for normal fertility in male mice.
Reproduction (Cambridge, England) 2004;127(4):503-11.
2004: Benjamin G Challis; Anthony P Coll; Giles S H Yeo; Scarlett B Pinnock; Suzanne Dickson; Rosemary R Thresher; Dixon John; Dirk Zahn; Justin J Rochford; A White; R L Oliver; George Millington; Samuel A J R Aparicio; William H Colledge; Andreas Russ; Mark B L Carlton; Stephen O'Rahilly
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4695-700.
2004: Eric Tse; A J H Smith; S Hunt; Isabelle Lavenir; Alan Forster; Amy J Warren; GG Grutz; L Foroni; Mark B L Carlton; William H Colledge; T Boehm; Terence H Rabbitts
Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice.
Molecular and cellular biology 2004;24(5):2063-73.
2003: Bernhard Payer; Mitinori Saitou; Sheila C Barton; Rosemary R Thresher; Dixon John; Dirk Zahn; William H Colledge; Mark B L Carlton; Toru Nakano; M Azim Surani
Stella is a maternal effect gene required for normal early development in mice.
Current biology : CB 2003;13(23):2110-7.
2003: Shirin S Joseph; James A Lynham; Peter Molenaar; Andrew A Grace; William H Colledge; Alberto J Kaumann
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2003;368(6):496-503.
2003: Stephanie B Seminara; Sophie Messager; Emmanouella E Chatzidaki; Rosemary R Thresher; James S Acierno; Jenna K Shagoury; Yousef Bo-Abbas; Wendy Kuohung; Kristine M Schwinof; Alan G Hendrick; Dirk Zahn; Dixon John; Ursula B Kaiser; Susan A Slaugenhaupt; James Gusella; Stephen O'Rahilly; Mark B L Carlton; William F Crowley; Samuel A J R Aparicio; William H Colledge
The GPR54 gene as a regulator of puberty.
The New England journal of medicine 2003;349(17):1614-27.
2003: John W Wiseman; Catharine Goddard; D McLelland; William H Colledge
A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo.
Gene therapy 2003;10(19):1654-62.
2003: H D Nickerson; William H Colledge
A comparison of gene repair strategies in cell culture using a lacZ reporter system.
Gene therapy 2003;10(18):1584-91.
2003: Ann E O Trezise; Luis Palazon; Wayne Davies; William H Colledge
In vivo gene expression: DNA electrotransfer.
Current opinion in molecular therapeutics 2003;5(4):397-404.
2002: A C Rose; Catharine Goddard; William H Colledge; Seng Cheng; Deborah R Gill; Stephen C Hyde
Optimisation of real-time quantitative RT-PCR for the evaluation of non-viral mediated gene transfer to the airways.
Gene therapy 2002;9(19):1312-20.
2002: G Alex Papadatos; Polly M R Wallerstein; Catherine E G Head; Rosemary Ratcliff; Peter A Brady; Klaus Benndorf; Richard C Saumarez; Ann E O Trezise; Christopher L-H Huang; Jamie I Vandenberg; William H Colledge; Andrew A Grace
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6210-5.
2001: John W Wiseman; Catharine Goddard; William H Colledge
Steroid hormone enhancement of gene delivery to a human airway epithelial cell line in vitro and mouse airways in vivo.
Gene therapy 2001;8(20):1562-71.
2001: Deborah R Gill; S E Smyth; Catharine Goddard; Ian Pringle; Christopher F Higgins; William H Colledge; Stephen C Hyde
Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter.
Gene therapy 2001;8(20):1539-46.
2001: Stefano Ferrari; Chris Kitson; Raymond Farley; RM Steel; C Marriott; D A Parkins; MAURIZIO SCARPA; Brandon J Wainwright; Martin J Evans; William H Colledge; Duncan M Geddes; Eric W F W Alton
Mucus altering agents as adjuncts for nonviral gene transfer to airway epithelium.
Gene therapy 2001;8(18):1380-6.
2001: Emily S Scott; John W Wiseman; Martin J Evans; William H Colledge
Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex.
The journal of gene medicine 2001;3(2):125-34.
2001: P Scheid; L Kempster; Uta Griesenbach; Jane C Davies; A Dewar; P P Weber; William H Colledge; Martin J Evans; Duncan M Geddes; Eric W F W Alton
Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(1):27-35.
2000: Catharine Goddard; Martin J Evans; William H Colledge
Genistein activates CFTR-mediated Cl(-) secretion in the murine trachea and colon.
American journal of physiology. Cell physiology 2000;279(2):C383-92.
2000: Stephen C Hyde; Kevin W Southern; Uzi Gileadi; E M Fitzjohn; KA Mofford; B E Waddell; H C Gooi; Catharine Goddard; K Hannavy; S E Smyth; J J Egan; FL Sorgi; L Huang; Alan W Cuthbert; Martin J Evans; William H Colledge; Christopher F Higgins; A K Webb; Deborah R Gill
Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis.
Gene therapy 2000;7(13):1156-65.
2000: Emily S Scott; Catharine Goddard; John W Wiseman; Martin J Evans; William H Colledge
A murine tracheal culture system to investigate parameters affecting gene therapy for cystic fibrosis.
Gene therapy 2000;7(7):612-8.
2000: Andreas Russ; Sigrid Wattler; William H Colledge; Samuel A J R Aparicio; Mark B L Carlton; J J Pearce; Sheila C Barton; M Azim Surani; Kenneth Ryan; Michael Nehls; V Wilson; Martin J Evans
Eomesodermin is required for mouse trophoblast development and mesoderm formation.
Nature 2000;404(6773):95-9.
1999: C Couldrey; Mark B L Carlton; P M Nolan; William H Colledge; Martin J Evans
A retroviral gene trap insertion into the histone 3.3A gene causes partial neonatal lethality, stunted growth, neuromuscular deficits and male sub-fertility in transgenic mice.
Human molecular genetics 1999;8(13):2489-95.
1998: C M Curtis; Lucy C Martin; Christopher F Higgins; William H Colledge; ME Hickman; Martin J Evans; Lesley MacVinish; Alan W Cuthbert
Restoration by intratracheal gene transfer of bicarbonate secretion in cystic fibrosis mouse gallbladder.
The American journal of physiology 1998;274(6 Pt 1):G1053-60.
1998: C Couldrey; Mark B L Carlton; J Ferrier; William H Colledge; Martin J Evans
Disruption of murine alpha-enolase by a retroviral gene trap results in early embryonic lethality.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;212(2):284-92.
1998: Mark B L Carlton; William H Colledge; Martin J Evans
Crouzon-like craniofacial dysmorphology in the mouse is caused by an insertional mutation at the Fgf3/Fgf4 locus.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;212(2):242-9.
1998: LS Friedman; FC Thistlethwaite; Ketan J Patel; VP Yu; H Lee; Ashok R Venkitaraman; K J Abel; Mark B L Carlton; S M Hunter; William H Colledge; Martin J Evans; Bruce A J Ponder
Thymic lymphomas in mice with a truncating mutation in Brca2.
Cancer research 1998;58(7):1338-43.
1998: D T Gilmour; G J Lyon; Mark B L Carlton; Joshua R Sanes; J M Cunningham; J R Anderson; B L Hogan; Martin J Evans; William H Colledge
Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.
The EMBO journal 1998;17(7):1860-70.
1998: Ketan J Patel; VP Yu; H Lee; A Corcoran; FC Thistlethwaite; Martin J Evans; William H Colledge; LS Friedman; Bruce A J Ponder; Ashok R Venkitaraman
Involvement of Brca2 in DNA repair.
Molecular cell 1998;1(3):347-57.
1997: Catharine Goddard; R Ratcliff; J R Anderson; E Glenn; S Brown; Deborah R Gill; Stephen C Hyde; Lesley MacVinish; L Huang; Christopher F Higgins; Alan W Cuthbert; Martin J Evans; William H Colledge
A second dose of a CFTR cDNA-liposome complex is as effective as the first dose in restoring cAMP-dependent chloride secretion to null CF mice trachea.
Gene therapy 1997;4(11):1231-6.
1997: Lesley MacVinish; Catharine Goddard; William H Colledge; Christopher F Higgins; Martin J Evans; Alan W Cuthbert
Normalization of ion transport in murine cystic fibrosis nasal epithelium using gene transfer.
The American journal of physiology 1997;273(2 Pt 1):C734-40.
1997: AL Manson; Ann E O Trezise; Lesley MacVinish; K D Kasschau; N Birchall; Vasso Episkopou; Georges VASSAUX; Martin J Evans; William H Colledge; Alan W Cuthbert; Clare Huxley
Complementation of null CF mice with a human CFTR YAC transgene.
The EMBO journal 1997;16(14):4238-49.
1997: Ann E O Trezise; R Ratcliff; T E Hawkins; Martin J Evans; T C Freeman; P R Romano; Christopher F Higgins; William H Colledge
Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice.
Human molecular genetics 1997;6(4):527-37.
1997: Lesley MacVinish; Deborah R Gill; Stephen C Hyde; KA Mofford; Martin J Evans; Christopher F Higgins; William H Colledge; L Huang; FL Sorgi; R Ratcliff; Alan W Cuthbert
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10-CFTR2.
The Journal of physiology 1997;499 ( Pt 3)():677-87.
1997: Deborah R Gill; Kevin W Southern; KA Mofford; T Seddon; L Huang; FL Sorgi; A Thomson; Lesley MacVinish; R Ratcliff; Diana Bilton; D J Lane; J M Littlewood; A K Webb; Peter G Middleton; William H Colledge; Alan W Cuthbert; Martin J Evans; Christopher F Higgins; Stephen C Hyde
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis.
Gene therapy 1997;4(3):199-209.
1996: A R Hayman; S J Jones; A Boyde; D Foster; William H Colledge; Mark B L Carlton; Martin J Evans; Timothy M Cox
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis.
Development (Cambridge, England) 1996;122(10):3151-62.
1995: T Neil Dear; William H Colledge; Mark B L Carlton; Isabelle Lavenir; T Larson; A J Smith; Amy J Warren; Martin J Evans; M V Sofroniew; Terence H Rabbitts
The Hox11 gene is essential for cell survival during spleen development.
Development (Cambridge, England) 1995;121(9):2909-15.
1995: William H Colledge; B S Abella; K W Southern; R Ratcliff; C Jiang; Seng Cheng; Lesley MacVinish; J R Anderson; Alan W Cuthbert; Martin J Evans
Generation and characterization of a delta F508 cystic fibrosis mouse model.
Nature genetics 1995;10(4):445-52.
1995: Mark B L Carlton; William H Colledge; Martin J Evans
Generation of a pseudogene during retroviral infection.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(2):90-5.
1995: Alan W Cuthbert; J Halstead; R Ratcliff; William H Colledge; Martin J Evans
The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine study.
The Journal of physiology 1995;482 ( Pt 2)():449-54.
1994: Alan W Cuthbert; Lesley MacVinish; ME Hickman; R Ratcliff; William H Colledge; Martin J Evans
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis.
Pflügers Archiv : European journal of physiology 1994;428(5-6):508-15.
1994: Alan W Cuthbert; Martin J Evans; William H Colledge; Lesley MacVinish; R Ratcliff
Kinin-stimulated chloride secretion in mouse colon requires the participation of CFTR chloride channels.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(8):1905-10.
1994: Amy J Warren; William H Colledge; Mark B L Carlton; Martin J Evans; A J Smith; Terence H Rabbitts
The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development.
Cell 1994;78(1):45-57.
1994: William H Colledge; Mark B L Carlton; G B Udy; Martin J Evans
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs.
Nature 1994;370(6484):65-8.
1994: Alan W Cuthbert; ME Hickman; Lesley MacVinish; Martin J Evans; William H Colledge; R Ratcliff; P W Seale; Patrick P A Humphrey
Chloride secretion in response to guanylin in colonic epithelial from normal and transgenic cystic fibrosis mice.
British journal of pharmacology 1994;112(1):31-6.
1993: R Ratcliff; Martin J Evans; Alan W Cuthbert; Lesley MacVinish; D Foster; J R Anderson; William H Colledge
Production of a severe cystic fibrosis mutation in mice by gene targeting.
Nature genetics 1993;4(1):35-41.
1993: Stephen C Hyde; Deborah R Gill; Christopher F Higgins; Ann E O Trezise; Lesley MacVinish; alan cuthbert; R Ratcliff; Martin J Evans; William H Colledge
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy.
Nature 1993;362(6417):250-5.
1992: R Ratcliff; Martin J Evans; J Doran; B J Wainwright; R Williamson; William H Colledge
Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting.
Transgenic research 1992;1(4):177-81.