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Kathleen Collins

Research Profile

Chemicals & Drugs

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HIV Infections

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Publications

TOP 3
Lucy A McNamara; Adewunmi Onafuwa-Nuga; James Riddell IV; Nadia T Sebastian; Dale Bixby; Kathleen L Collins
CD133+ Hematopoietic Progenitor Cells Harbor HIV Genomes in a Subset of Optimally Treated People With Long-Term Viral Suppression.
Lucy A McNamara; Kathleen L Collins
Interferon alfa therapy: toward an improved treatment for HIV infection.
Mike Mashiba; Kathleen L Collins
Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cells.

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All Publications

2013: Lucy A McNamara; Adewunmi Onafuwa-Nuga; James Riddell IV; Nadia T Sebastian; Dale Bixby; Kathleen L Collins
CD133+ Hematopoietic Progenitor Cells Harbor HIV Genomes in a Subset of Optimally Treated People With Long-Term Viral Suppression.
The Journal of infectious diseases 2013;207(12):1807-16.
2013: Lucy A McNamara; Kathleen L Collins
Interferon alfa therapy: toward an improved treatment for HIV infection.
The Journal of infectious diseases 2013;207(2):201-3.
2013: Mike Mashiba; Kathleen L Collins
Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cells.
Viruses 2013;5(1):1-14.
2012: Lucy A McNamara; Janani A Ganesh; Kathleen L Collins
Latent HIV-1 infection occurs in multiple subsets of hematopoietic progenitor cells and is reversed by NF-κB activation.
Journal of virology 2012;86(17):9337-50.
2012: Mike Mashiba; Kathleen L Collins
Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cells.
Viruses 2012;5(1):1-14.
2012: Anke Heigele; Jolie A Leonard; Clement W Gnanadurai; Kathleen L Collins; Michael Schindler; Frank Kirchhoff
Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins.
Journal of virology 2012;86(1):36-48.
2011: Elizabeth R Wonderlich; Deanna Kulpa; Jolie A Leonard; Kay E Leopold; Jason M Norman; Kathleen L Collins
ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.
Journal of virology 2011;85(23):12216-26.
2011: Deanna Kulpa; Kathleen L Collins
The emerging role of HLA-C in HIV-1 infection.
Immunology 2011;134(2):116-22.
2011: Jason M Norman; Adewunmi Onafuwa-Nuga; Wenwen Shen; Estelle Chiari-Fort; Michael Mashiba; Lucy A McNamara; Kathleen L Collins
The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells.
Nature immunology 2011;12(10):975-83.
2011: Jolie A Leonard; Malinda Schaefer; Christoph C Carter; Tracey M Filzen; Kathleen L Collins
HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elements.
Journal of virology 2011;85(14):6867-81.
2011: Christoph C Carter; Lucy A McNamara; Adewunmi Onafuwa-Nuga; Mark Shackleton; James Riddell IV; Dale Bixby; Michael R Savona; Sean J Morrison; Kathleen L Collins
HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells.
Cell host & microbe 2011;9(3):223-34.
2011: Elizabeth R Wonderlich; Jolie A Leonard; Kathleen L Collins
HIV immune evasion disruption of antigen presentation by the HIV Nef protein.
Advances in virus research 2011;80():103-27.
2011: Lucy A McNamara; Kathleen L Collins
Hematopoietic stem/precursor cells as HIV reservoirs.
Current opinion in HIV and AIDS 2011;6(1):43-8.
2010: Adewunmi Onafuwa-Nuga; Lucy A McNamara; Kathleen L Collins
Towards a cure for HIV: the identification and characterization of HIV reservoirs in optimally treated people.
Cell research 2010;20(11):1185-7.
2010: Jose L Garcia-Perez; Maria Morell; Joshua O Scheys; Deanna A Kulpa; Santiago Morell; Christoph C Carter; Gary Hammer; Kathleen L Collins; K Sue O'Shea; Pablo Menendez; John V Moran
Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.
Nature 2010;466(7307):769-73.
2010: Christoph C Carter; Adewunmi Onafuwa-Nuga; Lucy A McNamara; James Riddell IV; Dale Bixby; Michael R Savona; Kathleen L Collins
HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs.
Nature medicine 2010;16(4):446-51.
2009: Vilasack Thammavongsa; Malinda Schaefer; Tracey Filzen; Kathleen L Collins; Mary Carrington; Naveen Bangia; Malini Raghavan
Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503.
Immunogenetics 2009;61(11-12):703-16.
2009: Kathleen L Collins
This bud's for Vpu.
Cell host & microbe 2009;5(3):217-9.
2008: Malinda R Schaefer; Maya Williams; Deanna Kulpa; Pennelope K Blakely; Anna Q Yaffee; Kathleen L Collins
A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):7804-17.
2008: Elizabeth R Wonderlich; Maya Williams; Kathleen L Collins
The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail.
The Journal of biological chemistry 2008;283(6):3011-22.
2008: Malinda R Schaefer; Elizabeth R Wonderlich; Jeremiah F Roeth; Jolie A Leonard; Kathleen L Collins
HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.
PLoS pathogens 2008;4(8):e1000131.
2006: Vilasack Thammavongsa; Gayatri Raghuraman; Tracey M Filzen; Kathleen L Collins; Malini Raghavan
HLA-B44 polymorphisms at position 116 of the heavy chain influence TAP complex binding via an effect on peptide occupancy.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3150-61.
2006: Jeremiah F Roeth; Kathleen L Collins
Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways.
Microbiology and molecular biology reviews : MMBR 2006;70(2):548-63.
2005: Matthew R Kasper; Jeremiah F Roeth; Maya Williams; Tracey M Filzen; Rebekah I Fleis; Kathleen L Collins
HIV-1 Nef disrupts antigen presentation early in the secretory pathway.
The Journal of biological chemistry 2005;280(13):12840-8.
2005: Maya Williams; Jeremiah F Roeth; Matthew R Kasper; Tracey M Filzen; Kathleen L Collins
Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.
Journal of virology 2005;79(1):632-6.
2004: Jeremiah F Roeth; Maya Williams; Matthew R Kasper; Tracey M Filzen; Kathleen L Collins
HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.
The Journal of cell biology 2004;167(5):903-13.
2004: Kathleen L Collins
Resistance of HIV-infected cells to cytotoxic T lymphocytes.
Microbes and infection / Institut Pasteur 2004;6(5):494-500.
2003: Matthew R Kasper; Kathleen L Collins
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.
Journal of virology 2003;77(5):3041-9.
2003: kevin bobbitt; Marylyn M Addo; Marcus Altfeld; Tracey M Filzen; Adewunmi A Onafuwa; Bruce D Walker; Kathleen L Collins
Rev activity determines sensitivity of HIV-1-infected primary T cells to CTL killing.
Immunity 2003;18(2):289-99.
2003: Kathleen L Collins
How HIV evades CTL recognition.
Current HIV research 2003;1(1):31-40.
2002: Maya Williams; Jeremiah F Roeth; Matthew R Kasper; Rebekah I Fleis; Chris G Przybycin; Kathleen L Collins
Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking.
Journal of virology 2002;76(23):12173-84.
2002: Rebekah I Fleis; Tracey M Filzen; Kathleen L Collins
Species-specific effects of HIV-1 Nef-mediated MHC-I downmodulation.
Virology 2002;303(1):120-9.
2001: E Paulson; C Tran; Kathleen L Collins; Klaus J Frueh
KSHV-K5 inhibits phosphorylation of the major histocompatibility complex class I cytoplasmic tail.
Virology 2001;288(2):369-78.
2001: S A Swann; Maya Williams; C M Story; kevin bobbitt; Rebekah I Fleis; Kathleen L Collins
HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.
Virology 2001;282(2):267-77.
1999: Kathleen L Collins; Gary Nabel
Naturally attenuated HIV--lessons for AIDS vaccines and treatment.
The New England journal of medicine 1999;340(22):1756-7.
1999: Kathleen L Collins; David Baltimore
HIV's evasion of the cellular immune response.
Immunological reviews 1999;168():65-74.
1998: Kathleen L Collins; BK Chen; S A Kalams; Bruce D Walker; David Baltimore
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.
Nature 1998;391(6665):397-401.
1993: Kathleen L Collins; A A Russo; B Y Tseng; Thomas J Kelly
The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication.
The EMBO journal 1993;12(12):4555-66.
1992: Robert Ezzell; J Leung; Kathleen L Collins; M M Chafel; T J Cardozo; Paul Matsudaira
Expression and localization of villin, fimbrin, and myosin I in differentiating mouse F9 teratocarcinoma cells.
Developmental biology 1992;151(2):575-85.
1991: Kathleen L Collins; Thomas J Kelly
Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase.
Molecular and cellular biology 1991;11(4):2108-15.
1991: L F Erdile; Kathleen L Collins; A Russo; P Simancek; D Small; Christopher B Umbricht; D Virshup; L Cheng; S Randall; D Weinberg
Initiation of SV40 DNA replication: mechanism and control.
Cold Spring Harbor symposia on quantitative biology 1991;56():303-13.
1990: David Weinberg; Kathleen L Collins; P Simancek; A Russo; M S Wold; D M Virshup; Thomas J Kelly
Reconstitution of simian virus 40 DNA replication with purified proteins.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8692-6.
1987: A C Webb; Kathleen L Collins; S E Snyder; S J Alexander; L J Rosenwasser; R L Eddy; T B Shows; Philip E. auron
Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment, and homology to plasminogen activator-inhibitor.
The Journal of experimental medicine 1987;166(1):77-94.
1987: Matthew J Fenton; B D Clark; Kathleen L Collins; A C Webb; A Rich; Philip E. auron
Transcriptional regulation of the human prointerleukin 1 beta gene.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(11):3972-9.
1986: B D Clark; Kathleen L Collins; M S Gandy; A C Webb; Philip E. auron
Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene.
Nucleic acids research 1986;14(20):7897-914.
1986: A C Webb; Kathleen L Collins; Philip E. auron; R L Eddy; H Nakai; M G Byers; L L Haley; W M Henry; TB Shows
Interleukin-1 gene (IL1) assigned to long arm of human chromosome 2.
Lymphokine research 1986;5(2):77-85.
1982: Kathleen L Collins; E O Patrikas; G D Price
A training program for medical records personnel--a cooperative effort.
Topics in health record management 1982;3(2):22-9.