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Roberta Colman

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Anastasia F Thévenin; Chati L Zony; Brian J Bahnson; Roberta F Colman
GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2.
Lushanti De Zoysa Ariyananda; Christina Antonopoulos; Jenna Currier; Roberta F Colman
In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes.
Anastasia F Thévenin; Chati L Zony; Brian J Bahnson; Roberta F Colman
Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts.

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All Publications

2011: Anastasia F Thévenin; Chati L Zony; Brian J Bahnson; Roberta F Colman
GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2.
Protein science : a publication of the Protein Society 2011;20(5):834-48.
2011: Lushanti De Zoysa Ariyananda; Christina Antonopoulos; Jenna Currier; Roberta F Colman
In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes.
Biochemistry 2011;50(8):1336-46.
2011: Anastasia F Thévenin; Chati L Zony; Brian J Bahnson; Roberta F Colman
Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts.
Protein expression and purification 2011;75(2):138-46.
2010: Mayura Dange; Roberta F Colman
Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.
The Journal of biological chemistry 2010;285(27):20520-5.
2009: Lushanti De Zoysa Ariyananda; Peychii Lee; Christina Antonopoulos; Roberta F Colman
Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants.
Biochemistry 2009;48(23):5291-302.
2008: Yu-chu Huang; Stephanie Misquitta; Sylvie Blond; Elizabeth Adams; Roberta F Colman
Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits.
The Journal of biological chemistry 2008;283(47):32880-8.
2008: Dyonne T Hartong; Mayura Dange; Terri L McGee; Eliot L Berson; Thaddeus P Dryja; Roberta F Colman
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle.
Nature genetics 2008;40(10):1230-4.
2008: Sharmila Sivendran; Roberta F Colman
Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens.
Protein science : a publication of the Protein Society 2008;17(7):1162-74.
2008: Su-Hwi Hung; Andy H Liu; Robin A Pixley; Penelope Francis; LaTeeka D Williams; Christopher M Matsko; Karine D Barnes; Sharmila Sivendran; Roberta F Colman; Robert W Colman
A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A.
Bioorganic chemistry 2008;36(3):141-7.
2008: Luis A Ralat; Stephanie A Misquitta; Yefim Manevich; Aron B Fisher; Roberta F Colman
Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin.
Archives of biochemistry and biophysics 2008;474(1):109-18.
2008: Lushanti De Zoysa Ariyananda; Roberta F Colman
Evaluation of types of interactions in subunit association in Bacillus subtilis adenylosuccinate lyase.
Biochemistry 2008;47(9):2923-34.
2007: Sharmila Sivendran; Mark L Segall; Pumtiwitt C Rancy; Roberta F Colman
Effect of Asp69 and Arg310 on the pK of His68, a key catalytic residue of adenylosuccinate lyase.
Protein science : a publication of the Protein Society 2007;16(8):1700-7.
2007: May Tsai; Jason Koo; Patrick Yip; Roberta F Colman; Mark L Segall; P Lynne Howell
Substrate and product complexes of Escherichia coli adenylosuccinate lyase provide new insights into the enzymatic mechanism.
Journal of molecular biology 2007;370(3):541-54.
2007: Krzysztof P Bzymek; Roberta F Colman
Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.
Biochemistry 2007;46(18):5391-7.
2007: Mark L Segall; Meghan A Cashman; Roberta F Colman
Important roles of hydroxylic amino acid residues in the function of Bacillus subtilis adenylosuccinate lyase.
Protein science : a publication of the Protein Society 2007;16(3):441-8.
2007: Peychii Lee; Roberta F Colman
Expression, purification, and characterization of stable, recombinant human adenylosuccinate lyase.
Protein expression and purification 2007;51(2):227-34.
2006: Luis A Ralat; Roberta F Colman
Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi.
Biochemistry 2006;45(41):12491-9.
2006: Su-Hwi Hung; Wei Zhang; Robin A Pixley; Bradford A Jameson; Yu Chu Huang; Roberta F Colman; Robert W Colman
New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert.
The Journal of biological chemistry 2006;281(39):29236-44.
2006: Erin K Spiegel; Roberta F Colman; David Patterson
Adenylosuccinate lyase deficiency.
Molecular genetics and metabolism 2006;89(1-2):19-31.
2006: Sambanthamurthy Soundar; Molly O'hagan; Kenneth S Fomulu; Roberta F Colman
Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 2006;281(30):21073-81.
2006: Peychii Lee; Roberta F Colman
Thr373, Asp375, and Lys260 are in the coenzyme site of porcine NADP-dependent isocitrate dehydrogenase.
Archives of biochemistry and biophysics 2006;450(2):183-90.
2006: Jennifer L Hearne; Roberta F Colman
Contribution of the mu loop to the structure and function of rat glutathione transferase M1-1.
Protein science : a publication of the Protein Society 2006;15(6):1277-89.
2006: Siobhàn M O'Sullivan; Ronan M McCarthy; Melissa A Vargo; Roberta F Colman; David Sheehan
Chemical modification at subunit 1 of rat kidney Alpha class glutathione transferase with 2,3,5,6-tetrachloro-1,4-benzoquinone: close structural connectivity between glutathione conjugation activity and non-substrate ligand binding.
Biochemical pharmacology 2006;71(11):1629-36.
2006: Jennifer L Hearne; Roberta F Colman
Catalytically active monomer of class mu glutathione transferase from rat.
Biochemistry 2006;45(19):5974-84.
2006: Luis A Ralat; Yefim Manevich; Aron B Fisher; Roberta F Colman
Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes.
Biochemistry 2006;45(2):360-72.
2005: Jennifer L Hearne; Roberta F Colman
Delineation of xenobiotic substrate sites in rat glutathione S-transferase M1-1.
Protein science : a publication of the Protein Society 2005;14(10):2526-36.
2005: Yu Chu Huang; Roberta F Colman
Location of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 2005;280(34):30349-53.
2005: Stephanie A Misquitta; Roberta F Colman
Communication between the two active sites of glutathione S-transferase A1-1, probed using wild-type-mutant heterodimers.
Biochemistry 2005;44(24):8608-19.
2005: Peychii Lee; Roberta F Colman
Adenosine 2'-monophosphate, 5'-O-[S-(4-succinimidylbenzophenone)-thiophosphate]: a new photoaffinity label for the coenzyme site of porcine NADP-specific isocitrate dehydrogenase.
Bioconjugate chemistry 2005;16(3):650-9.
2005: Tae-Kang Kim; Roberta F Colman
Ser95, Asn97, and Thr78 are important for the catalytic function of porcine NADP-dependent isocitrate dehydrogenase.
Protein science : a publication of the Protein Society 2005;14(1):140-7.
2004: Sharmila Sivendran; David Patterson; Erin Spiegel; Ivan McGown; David Cowley; Roberta F Colman
Two novel mutant human adenylosuccinate lyases (ASLs) associated with autism and characterization of the equivalent mutant Bacillus subtilis ASL.
The Journal of biological chemistry 2004;279(51):53789-97.
2004: Luis A Ralat; Roberta F Colman
Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.
The Journal of biological chemistry 2004;279(48):50204-13.
2004: Mark L Segall; Roberta F Colman
Gln212, Asn270, and Arg301 are critical for catalysis by adenylosuccinate lyase from Bacillus subtilis.
Biochemistry 2004;43(23):7391-402.
2004: Melissa A Vargo; Roberta F Colman
Heterodimers of wild-type and subunit interface mutant enzymes of glutathione S-transferase A1-1: interactive or independent active sites?
Protein science : a publication of the Protein Society 2004;13(6):1586-93.
2004: Melissa A Vargo; Lucia Nguyen; Roberta F Colman
Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibrium.
Biochemistry 2004;43(12):3327-35.
2004: Yu Chu Huang; Neil B Grodsky; Tae-Kang Kim; Roberta F Colman
Ligands of the Mn2+ bound to porcine mitochondrial NADP-dependent isocitrate dehydrogenase, as assessed by mutagenesis.
Biochemistry 2004;43(10):2821-8.
2003: Sambanthamurthy Soundar; Jung-Hoon Park; Tae-Lin Huh; Roberta F Colman
Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 2003;278(52):52146-53.
2003: Tae-Kang Kim; Peychii Lee; Roberta F Colman
Critical role of Lys212 and Tyr140 in porcine NADP-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 2003;278(49):49323-31.
2003: Luis A Ralat; Roberta F Colman
Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase pi.
Protein science : a publication of the Protein Society 2003;12(11):2575-87.
2003: Jennifer Brosius Palenchar; Jennifer M Crocco; Roberta F Colman
The characterization of mutant Bacillus subtilis adenylosuccinate lyases corresponding to severe human adenylosuccinate lyase deficiencies.
Protein science : a publication of the Protein Society 2003;12(8):1694-705.
2003: Jennifer Brosius Palenchar; Roberta F Colman
Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.
Biochemistry 2003;42(7):1831-41.
2002: Christopher Ceccarelli; Neil B Grodsky; Nandana Ariyaratne; Roberta F Colman; Brian J Bahnson
Crystal structure of porcine mitochondrial NADP+-dependent isocitrate dehydrogenase complexed with Mn2+ and isocitrate. Insights into the enzyme mechanism.
The Journal of biological chemistry 2002;277(45):43454-62.
2002: Peychii Lee; Roberta F Colman
Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
Archives of biochemistry and biophysics 2002;401(1):81-90.
2002: Yu Chu Huang; Roberta F Colman
Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase.
Biochemistry 2002;41(17):5637-43.
2002: Su-Hwi Hung; kol madhusoodanan; Robert L Boyd; James L Baldwin; Roberta F Colman; Robert W Colman
A nonhydrolyzable reactive cAMP analogue, (S(p))-8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic S-(methyl)monophosphorothioate, irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase at micromolar concentrations.
Biochemistry 2002;41(9):2962-9.
2002: Jennifer L Brosius; Roberta F Colman
Three subunits contribute amino acids to the active site of tetrameric adenylosuccinate lyase: Lys268 and Glu275 are required.
Biochemistry 2002;41(7):2217-26.
2002: Su-Hwi Hung; kol madhusoodanan; James A Beres; Robert L Boyd; James L Baldwin; Wei Zhang; Robert W Colman; Roberta F Colman
A new nonhydrolyzable reactive cAMP analog, (Sp)-adenosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase.
Bioorganic chemistry 2002;30(1):16-31.
2001: NE Pettigrew; Roberta F Colman
Heterodimers of glutathione S-transferase can form between isoenzyme classes pi and mu.
Archives of biochemistry and biophysics 2001;396(2):225-30.
2001: NE Pettigrew; E J Brush; Roberta F Colman
3-Methyleneoxindole: an affinity label of glutathione S-transferase pi which targets tryptophan 38.
Biochemistry 2001;40(25):7549-58.
2001: kol madhusoodanan; Roberta F Colman
Adenosine 5'-0-[S-(4-succinimidyl-benzophenone)thiophosphate]: a new photoaffinity label of the allosteric ADP site of bovine liver glutamate dehydrogenase.
Biochemistry 2001;40(6):1577-86.
2001: Melissa A Vargo; Roberta F Colman
Affinity labeling of rat glutathione S-transferase isozyme 1-1 by 17beta -iodoacetoxy-estradiol-3-sulfate.
The Journal of biological chemistry 2001;276(3):2031-6.
2000: J L Brosius; Roberta F Colman
A key role in catalysis for His89 of adenylosuccinate lyase of Bacillus subtilis.
Biochemistry 2000;39(44):13336-43.
2000: F Mseeh; Roberta F Colman; Robert W Colman
Inactivation of platelet PDE2 by an affinity label: 8-[(4-bromo-2, 3-dioxobutyl)thio]cAMP.
Thrombosis research 2000;98(5):395-401.
2000: Neil B Grodsky; Sambanthamurthy Soundar; Roberta F Colman
Evaluation by site-directed mutagenesis of aspartic acid residues in the metal site of pig heart NADP-dependent isocitrate dehydrogenase.
Biochemistry 2000;39(9):2193-200.
2000: Sambanthamurthy Soundar; Brenda L Danek; Roberta F Colman
Identification by mutagenesis of arginines in the substrate binding site of the porcine NADP-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 2000;275(8):5606-12.
2000: J d Wang; S Bauman; Roberta F Colman
Probing subunit interactions in alpha class rat liver glutathione S-transferase with the photoaffinity label glutathionyl S-[4-(succinimidyl)benzophenone].
The Journal of biological chemistry 2000;275(8):5493-503.
2000: Yu Chu Huang; Sambanthamurthy Soundar; Roberta F Colman
Affinity cleavage at the divalent metal site of porcine NAD-specific isocitrate dehydrogenase.
Protein science : a publication of the Protein Society 2000;9(1):104-11.
1999: Peychii Lee; Andrea Gorrell; Herbert J Fromm; Roberta F Colman
8-(4-Bromo-2,3-dioxobutylthio)guanosine 5'-triphosphate: a new affinity label for purine nucleotide sites in proteins.
Archives of biochemistry and biophysics 1999;372(1):205-13.
1999: Peychii Lee; Andrea Gorrell; Herbert J Fromm; Roberta F Colman
Implication of arginine-131 and arginine-303 in the substrate site of adenylosuccinate synthetase of Escherichia coli by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate.
Biochemistry 1999;38(18):5754-63.
1999: NE Pettigrew; M Moyer-Myers; Roberta F Colman
Affinity labeling of pig lung glutathione S-transferase pi by 4-(fluorosulfonyl)benzoic acid.
Archives of biochemistry and biophysics 1999;364(1):107-14.
1999: TT Lee; Carolyn A Worby; Zhao Qin Bao; Jack E Dixon; Roberta F Colman
His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis.
Biochemistry 1999;38(1):22-32.
1998: J d Wang; S Bauman; Roberta F Colman
Photoaffinity labeling of rat liver glutathione S-transferase, 4-4, by glutathionyl S-[4-(succinimidyl)-benzophenone].
Biochemistry 1998;37(45):15671-9.
1998: TT Lee; Carolyn A Worby; Zhao Qin Bao; Jack E Dixon; Roberta F Colman
Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate.
Biochemistry 1998;37(23):8481-9.
1998: H Chen; Yu Chu Huang; Roberta F Colman
Identification of the subunit and important target peptides of pig heart NAD-dependent isocitrate dehydrogenase modified by the affinity label adenosine 5'-O-[S-(4-bromo-2, 3-dioxobutyl)thiophosphate].
Biochemistry 1998;37(18):6541-51.
1997: Yu Chu Huang; A Kumar; Roberta F Colman
Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD.
Archives of biochemistry and biophysics 1997;348(1):207-18.
1997: J J Barycki; Roberta F Colman
Identification of the nonsubstrate steroid binding site of rat liver glutathione S-transferase, isozyme 1-1, by the steroid affinity label, 3beta-(iodoacetoxy)dehydroisoandrosterone.
Archives of biochemistry and biophysics 1997;345(1):16-31.
1997: RN Puri; Roberta F Colman; Robert W Colman
Modulation of platelet responses by 2-[3-(bromo-2-oxopropylthio)]adenosine-5'-diphosphate involves its binding to as well as covalent modification of an ADP-receptor, aggregin.
Archives of biochemistry and biophysics 1997;343(1):140-5.
1997: Roberta F Colman
Chemical arrows for enzymatic targets.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(4):217-26.
1997: Longqin Hu; Roberta F Colman
Resonance energy transfer between sites in rat liver glutathione S-transferase, 1-1, selectively modified at cysteine-17 and cysteine-111.
Biochemistry 1997;36(7):1635-45.
1997: GA Omburo; Theodore J Torphy; G Scott; S Jacobitz; Roberta F Colman; Robert W Colman
Inactivation of recombinant monocyte cAMP-specific phosphodiesterase by cAMP analog, 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic monophosphate.
Blood 1997;89(3):1019-26.
1997: TT Lee; Carolyn A Worby; Jack E Dixon; Roberta F Colman
Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate.
The Journal of biological chemistry 1997;272(1):458-65.
1997: Roberta F Colman
Affinity labels for NAD(P)-specific sites.
Methods in enzymology 1997;280():186-203.
1997: Longqin Hu; B L Borleske; Roberta F Colman
Probing the active site of alpha-class rat liver glutathione S-transferases using affinity labeling by monobromobimane.
Protein science : a publication of the Protein Society 1997;6(1):43-52.
1996: S Soundar; G T Jennings; Lee McAlister-Henn; Roberta F Colman
Expression of pig heart mitochondrial NADP-dependent isocitrate dehydrogenase in Escherichia coli.
Protein expression and purification 1996;8(3):305-12.
1996: O A Moe; J F Baker-Malcolm; W Wang; C Kang; Herbert J Fromm; Roberta F Colman
Involvement of arginine 143 in nucleotide substrate binding at the active site of adenylosuccinate synthetase from Escherichia coli.
Biochemistry 1996;35(28):9024-33.
1996: J Wang; J J Barycki; Roberta F Colman
Tyrosine 8 contributes to catalysis but is not required for activity of rat liver glutathione S-transferase, 1-1.
Protein science : a publication of the Protein Society 1996;5(6):1032-42.
1996: RN Puri; Roberta F Colman; Robert W Colman
Platelet activation by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-diphosphate is mediated by its binding to a putative ADP receptor, aggregin.
European journal of biochemistry / FEBS 1996;236(3):862-70.
1996: S U Gite; Roberta F Colman
Affinity Labeling of the active site of rabbit muscle adenylosuccinate lyase by 2-[(4-bromo-2.3-dioxobutyl)thio] adenosine 5'-monophosphate.
Biochemistry 1996;35(8):2658-67.
1995: RN Puri; A Kumar; H Chen; Roberta F Colman; Robert W Colman
Inhibition of ADP-induced platelet responses by covalent modification of aggregin, a putative ADP receptor, by 8-(4-bromo-2,3-dioxobutylthio)ADP.
The Journal of biological chemistry 1995;270(41):24482-8.
1995: Longqin Hu; Roberta F Colman
Monobromobimane as an affinity label of the xenobiotic binding site of rat glutathione S-transferase 3-3.
The Journal of biological chemistry 1995;270(37):21875-83.
1995: R S Ehrlich; Roberta F Colman
Cadmium-113 and magnesium-25 NMR study of the divalent metal binding sites of isocitrate dehydrogenases from pig heart.
Biochimica et biophysica acta 1995;1246(2):135-41.
1995: Yu Chu Huang; R J Haselbeck; Lee McAlister-Henn; Roberta F Colman
N-ethylmaleimide profiling of yeast NADP-dependent isocitrate dehydrogenase.
Archives of biochemistry and biophysics 1995;316(1):485-92.
1995: Roberta F Colman
Affinity labeling and related approaches to targeting specific enzyme sites.
Sub-cellular biochemistry 1995;24():177-205.
1994: K O Wrzeszczynski; Roberta F Colman
Activation of bovine liver glutamate dehydrogenase by covalent reaction of adenosine 5'-O-[S-(4-bromo-2,3-dioxobutyl)thiophosphate] with arginine-459 at an ADP regulatory site.
Biochemistry 1994;33(38):11544-53.
1994: S H Vollmer; M B Walner; K V Tarbell; Roberta F Colman
Guanosine 5'-O-[S-(4-bromo-2,3-dioxobutyl)]thiophosphate and adenosine 5'-O-[S-(4-bromo-2,3-dioxobutyl)]thiophosphate. New nucleotide affinity labels which react with rabbit muscle pyruvate kinase.
The Journal of biological chemistry 1994;269(11):8082-90.
1994: A Kumar; Roberta F Colman
8-(4-Bromo-2,3-dioxobutylthio)NAD: a new affinity label for NAD-specific isocitrate dehydrogenase.
Archives of biochemistry and biophysics 1994;308(2):357-66.
1993: J J Barycki; Roberta F Colman
Affinity labeling of glutathione S-transferase, isozyme 4-4, by 4-(fluorosulfonyl)benzoic acid reveals Tyr115 to be an important determinant of xenobiotic substrate specificity.
Biochemistry 1993;32(48):13002-11.
1993: I Park; D H Ozturk; S Soundar; Roberta F Colman
Nicotinamide ribose 5'-O-[S-(3-bromo-2-oxopropyl)]thiophosphate: a new affinity label for NMN sites in enzymes.
Archives of biochemistry and biophysics 1993;303(2):483-8.
1993: S Soundar; Roberta F Colman
Identification of metal-isocitrate binding site of pig heart NADP-specific isocitrate dehydrogenase by affinity cleavage of the enzyme by Fe(2+)-isocitrate.
The Journal of biological chemistry 1993;268(7):5264-71.
1992: R S Ehrlich; Roberta F Colman
Selectivity in the binding of NAD(P)+ analogues to NAD- and NADP-dependent pig heart isocitrate dehydrogenases. A nuclear magnetic resonance study.
Biochemistry 1992;31(49):12524-31.
1992: D H Ozturk; I Park; Roberta F Colman
Guanosine 5'-O-[S-(3-bromo-2-oxopropyl)]thiophosphate: a new reactive purine nucleotide analog labeling Met-169 and Tyr-262 in bovine liver glutamate dehydrogenase.
Biochemistry 1992;31(43):10544-55.
1992: R M Katusz; B Bono; Roberta F Colman
Identification of Tyr115 labeled by S-(4-bromo-2,3-dioxobutyl)glutathione in the hydrophobic substrate binding site of glutathione S-transferase, isoenzyme 3-3.
Archives of biochemistry and biophysics 1992;298(2):667-77.
1992: R M Katusz; B Bono; Roberta F Colman
Affinity labeling of Cys111 of glutathione S-transferase, isoenzyme 1-1, by S-(4-bromo-2,3-dioxobutyl)glutathione.
Biochemistry 1992;31(37):8984-90.
1992: L Haeffner-Gormley; Z Chen; H Zalkin; Roberta F Colman
Importance of lysine-286 at the NADP site of glutamate dehydrogenase from Salmonella typhimurium.
Biochemistry 1992;31(34):7807-14.
1992: R J Haselbeck; Roberta F Colman; Lee McAlister-Henn
Isolation and sequence of a cDNA encoding porcine mitochondrial NADP-specific isocitrate dehydrogenase.
Biochemistry 1992;31(27):6219-23.
1992: S H Vollmer; Roberta F Colman
Cysteinyl peptides labeled by dibromobutanedione in reaction with rabbit muscle pyruvate kinase.
Protein science : a publication of the Protein Society 1992;1(5):678-87.
1992: K E Dombrowski; Yu Chu Huang; Roberta F Colman
Identification of amino acids modified by the bifunctional affinity label 5'-(p-(fluorosulfonyl)benzoyl)-8-azidoadenosine in the reduced coenzyme regulatory site of bovine liver glutamate dehydrogenase.
Biochemistry 1992;31(15):3785-93.
1992: D C Mills; R Puri; C J Hu; C Minniti; G Grana; M D Freedman; Roberta F Colman; Robert W Colman
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(4):430-6.
1992: G E Smyth; Roberta F Colman
Inactivation of pig heart NADP-specific isocitrate dehydrogenase by two affinity reagents is due to reaction with a cysteine not essential for function.
Archives of biochemistry and biophysics 1992;293(2):356-61.
1992: W R Figures; L M Scearce; Roberta F Colman; Robert W Colman
Interaction of nucleotide affinity analog 5'-p-fluorosulfonylbenzoyladenosine with platelet ADP receptor: aggregin.
Methods in enzymology 1992;215():143-55.
1992: P G Grant; D L DeCamp; J M Bailey; Roberta F Colman; Robert W Colman
Low-Km cyclic AMP phosphodiesterase from human platelets. Stimulation of activity by phosphorylation of the enzyme and affinity labeling of the active site.
Advances in second messenger and phosphoprotein research 1992;25():73-85.
1992: L Haeffner-Gormley; Z D Chen; H Zalkin; Roberta F Colman
Reaction of the nucleotide analogue 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 2',5'-bisphosphate at the coenzyme site of wild-type and mutant NADP(+)-specific glutamate dehydrogenases from Salmonella typhimurium.
Archives of biochemistry and biophysics 1992;292(1):179-89.
1991: R M Katusz; Roberta F Colman
S-(4-Bromo-2,3-dioxobutyl)glutathione: a new affinity label for the 4-4 isoenzyme of rat liver glutathione S-transferase.
Biochemistry 1991;30(47):11230-8.
1991: G E Smyth; Roberta F Colman
Cysteinyl peptides of pig heart NADP-dependent isocitrate dehydrogenase that are modified upon inactivation by N-ethylmaleimide.
The Journal of biological chemistry 1991;266(23):14918-25.
1991: D H Ozturk; Roberta F Colman
Identification of cysteine-319 as the target amino acid of 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-triphosphate in bovine liver glutamate dehydrogenase.
Biochemistry 1991;30(29):7126-34.
1991: L Haeffner-Gormley; Z D Chen; H Zalkin; Roberta F Colman
Evaluation of cysteine 283 and glutamic acid 284 in the coenzyme binding site of Salmonella typhimurium glutamate dehydrogenase by site-directed mutagenesis and reaction with the nucleotide analogue 2-[4-bromo-2,3-dioxobutyl)thio)-1,N6-ethenoadenosine 2',5'-bisphosphate.
The Journal of biological chemistry 1991;266(9):5388-94.
1991: RN Puri; F Zhou; C J Hu; Roberta F Colman; Robert W Colman
High molecular weight kininogen inhibits thrombin-induced platelet aggregation and cleavage of aggregin by inhibiting binding of thrombin to platelets.
Blood 1991;77(3):500-7.
1990: RN Puri; F X Zhou; Roberta F Colman; Robert W Colman
Plasmin-induced platelet aggregation is accompanied by cleavage of aggregin and indirectly mediated by calpain.
The American journal of physiology 1990;259(6 Pt 1):C862-8.
1990: Yu Chu Huang; Roberta F Colman
Subunit location and sequences of the cysteinyl peptides of pig heart NAD-dependent isocitrate dehydrogenase.
Biochemistry 1990;29(36):8266-73.
1990: D H Ozturk; D Safer; Roberta F Colman
Affinity labeling of bovine liver glutamate dehydrogenase with 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-diphosphate and 5'-triphosphate.
Biochemistry 1990;29(30):7112-8.
1990: R S Ehrlich; Roberta F Colman
Conformations of the coenzymes and the allosteric activator, ADP, bound to NAD(+)-dependent isocitrate dehydrogenase from pig heart.
Biochemistry 1990;29(21):5179-87.
1990: S H Vollmer; Roberta F Colman
Cysteinyl peptides of rabbit muscle pyruvate kinase labeled by the affinity label 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-triphosphate.
Biochemistry 1990;29(10):2495-501.
1990: R H Lark; Roberta F Colman
Distance between the substrate and regulatory reduced coenzyme binding sites of bovine liver glutamate dehydrogenase by resonance energy transfer.
European journal of biochemistry / FEBS 1990;188(2):377-83.
1990: P G Grant; D L DeCamp; J M Bailey; Robert W Colman; Roberta F Colman
Three new potential cAMP affinity labels. Inactivation of human platelet low Km cAMP phosphodiesterase by 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic monophosphate.
Biochemistry 1990;29(4):887-94.
1990: Roberta F Colman; J M Bailey; D L DeCamp; Yu Chu Huang; S H Vollmer
Affinity labeling of adenine nucleotide sites in enzymes.
Annals of the New York Academy of Sciences 1990;603():417-26.
1990: Roberta F Colman
Affinity labeling of nucleotide binding sites of enzymes and platelets.
Advances in experimental medicine and biology 1990;281():257-63.
1989: K E Dombrowski; Roberta F Colman
5'-p-fluorosulfonyl)benzoyl-8-azidoadenosine: a new bifunctional affinity label for nucleotide binding sites in proteins.
Archives of biochemistry and biophysics 1989;275(1):302-8.
1989: A Saha; Yu Chu Huang; Roberta F Colman
Cysteinyl peptide labeled by 3-bromo-2-ketoglutarate in the active site of pig heart NAD+-dependent isocitrate dehydrogenase.
Biochemistry 1989;28(21):8425-31.
1989: RN Puri; F X Zhou; Roberta F Colman; Robert W Colman
Cleavage of a 100 kDa membrane protein (aggregin) during thrombin-induced platelet aggregation is mediated by the high affinity thrombin receptors.
Biochemical and biophysical research communications 1989;162(3):1017-24.
1989: Yu Chu Huang; Roberta F Colman
Aspartyl peptide labeled by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-diphosphate in the allosteric ADP site of pig heart NAD+-dependent isocitrate dehydrogenase.
The Journal of biological chemistry 1989;264(21):12208-14.
1989: A Bansal; M A Dayton; H Zalkin; Roberta F Colman
Affinity labeling of a glutamyl peptide in the coenzyme binding site of NADP+-specific glutamate dehydrogenase of Salmonella typhimurium by 2-[(4-bromo-2,3-dioxobutyl)thio]-1,N6-ethenoadenosine 2',5'-bisphosphate.
The Journal of biological chemistry 1989;264(17):9827-35.
1989: RN Puri; F X Zhou; H Bradford; C J Hu; Roberta F Colman; Robert W Colman
Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain.
Archives of biochemistry and biophysics 1989;271(2):346-58.
1989: D L DeCamp; Roberta F Colman
2-[(4-Bromo-2,3-dioxobutyl)thio]-1,N6-ethenoadenosine 5'-diphosphate. A new fluorescent affinity label of a tyrosyl residue in the active site of rabbit muscle pyruvate kinase.
The Journal of biological chemistry 1989;264(14):8430-41.
1989: S P Batra; R H Lark; Roberta F Colman
Identification of histidyl peptide labeled by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-monophosphate in an ADP regulatory site of glutamate dehydrogenase.
Archives of biochemistry and biophysics 1989;270(1):277-85.
1989: Roberta F Colman
Affinity labels and spectroscopic probes of porcine heart NADP-dependent isocitrate dehydrogenase.
Biochemical Society transactions 1989;17(2):307-11.
1989: R S Ehrlich; Roberta F Colman
Multinuclear NMR studies of the divalent metal binding site of NADP-dependent isocitrate dehydrogenase from pig heart.
Biochemistry 1989;28(5):2058-65.
1988: D L DeCamp; S Lim; Roberta F Colman
Reaction of pyruvate kinase with the new nucleotide affinity labels 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-diphosphate and 5'-triphosphate.
Biochemistry 1988;27(20):7651-8.
1988: A Saha; Roberta F Colman
Modification of NAD-dependent isocitrate dehydrogenase by the 2',3'-dialdehyde derivatives of NAD, NADH, NADP, and NADPH.
Archives of biochemistry and biophysics 1988;264(2):665-77.
1988: Robert W Colman; W R Figures; Q X Wu; S Y Chung; Thomas A Morinelli; George P Tuszynski; Roberta F Colman; Stefan Niewiarowski
Distinction between glycoprotein IIIa and the 100-kDa membrane protein (aggregin) mediating ADP-induced platelet activation.
Archives of biochemistry and biophysics 1988;262(1):298-306.
1988: Robert W Colman; RN Puri; F X Zhou; Roberta F Colman
Aggregin: the platelet receptor mediating activation by ADP.
Progress in clinical and biological research 1988;283():263-77.
1987: J M Bailey; Roberta F Colman
2-[(4-Bromo-2,3-dioxobutyl)thio]- and 2-[(3-bromo-2-oxopropyl)thio]adenosine 2'5'-bisphosphate: new nucleotide analogues that act as affinity labels of nicotinamide adenine dinucleotide phosphate specific isocitrate dehydrogenase.
Biochemistry 1987;26(21):6858-69.
1987: W R Figures; L M Scearce; P DeFeo; G Stewart; F Zhou; J Chen; J Daniel; Roberta F Colman; Robert W Colman
Direct evidence for the interaction of the nucleotide affinity analog 5'-p-fluorosulfonylbenzoyl adenosine with a platelet ADP receptor.
Blood 1987;70(3):796-803.
1987: J M Bailey; Roberta F Colman
Distances among coenzyme and metal sites of NADP+-dependent isocitrate dehydrogenase using resonance energy transfer.
Biochemistry 1987;26(15):4893-900.
1987: R S Ehrlich; Roberta F Colman
Ionization of isocitrate bound to pig heart NADP+-dependent isocitrate dehydrogenase: 13C NMR study of substrate binding.
Biochemistry 1987;26(12):3461-6.
1987: RN Puri; E J Gustafson; F X Zhou; H Bradford; Roberta F Colman; Robert W Colman
Inhibition of thrombin-induced platelet aggregation by high molecular weight kininogen.
Transactions of the Association of American Physicians 1987;100():232-40.
1986: W R Figures; L M Scearce; Y Wachtfogel; J Chen; Roberta F Colman; Robert W Colman
Platelet ADP receptor and alpha 2-adrenoreceptor interaction. Evidence for an ADP requirement for epinephrine-induced platelet activation and an influence of epinephrine on ADP binding.
The Journal of biological chemistry 1986;261(13):5981-6.
1986: Robert W Colman; W R Figures; Q X Wu; S Y Chung; Thomas A Morinelli; George P Tuszynski; Roberta F Colman; Stefan Niewiarowski
Separation of the 100-kDa membrane protein mediating ADP-induced platelet shape change and activation from glycoprotein IIIa.
Transactions of the Association of American Physicians 1986;99():39-45.
1985: D C Mills; W R Figures; L M Scearce; G J Stewart; Roberta F Colman; Robert W Colman
Two mechanisms for inhibition of ADP-induced platelet shape change by 5'-p-fluorosulfonylbenzoyladenosine. Conversion to adenosine, and covalent modification at an ADP binding site distinct from that which inhibits adenylate cyclase.
The Journal of biological chemistry 1985;260(13):8078-83.
1981: W R Figures; Stefan Niewiarowski; Thomas A Morinelli; Roberta F Colman; Robert W Colman
Affinity labeling of a human platelet membrane protein with 5'-p-fluorosulfonylbenzoyl adenosine. Concomitant inhibition of ADP-induced platelet aggregation and fibrinogen receptor exposure.
The Journal of biological chemistry 1981;256(15):7789-95.
1980: Robert W Colman; W R Figures; Roberta F Colman; Thomas A Morinelli; Stefan Niewiarowski; D C Mills
Identification of two distinct adenosine diphosphate receptors in human platelets.
Transactions of the Association of American Physicians 1980;93():305-16.