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Antonio Coluccia

Research Profile

Chemicals & Drugs

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HIV-1

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Publications

TOP 3
Marcella Bassetto; Giampiero Colombano; Antonio Coluccia; Tine De Burghgraeve; Leen Delang; Valerio Gatti; Pieter Leyssen; Alberto Massarotti; Johan Neyts; Romano Silvestri; Giovanni Sorba; Gian Cesare Tron; Nicola Zonta; Andrea Brancale
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus.
Giuseppe La Regina; giovanni maga; Ettore Novellino; Francesco Piscitelli; Alberta Samuele; Dominique Schols; Andrea Brancale; Bonaventura Clotet; Antonio Coluccia; Sandro Cosconati; José A Esté; Valeria Famiglini; Emmanuel Gonzalez; Romano Silvestri
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
Francesco Piscitelli; Marco Allarà; Antonio Coluccia; Vincenzo Di Marzo; Giuseppe La Regina; Alessia Ligresti; Ludovica Morera; Ettore Novellino; Romano Silvestri
Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.

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All Publications

2013: Marcella Bassetto; Giampiero Colombano; Antonio Coluccia; Tine De Burghgraeve; Leen Delang; Valerio Gatti; Pieter Leyssen; Alberto Massarotti; Johan Neyts; Romano Silvestri; Giovanni Sorba; Gian Cesare Tron; Nicola Zonta; Andrea Brancale
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus.
Antiviral research 2013;98(1):12-8.
2012: Giuseppe La Regina; giovanni maga; Ettore Novellino; Francesco Piscitelli; Alberta Samuele; Dominique Schols; Andrea Brancale; Bonaventura Clotet; Antonio Coluccia; Sandro Cosconati; José A Esté; Valeria Famiglini; Emmanuel Gonzalez; Romano Silvestri
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
Journal of medicinal chemistry 2012;55(14):6634-8.
2012: Francesco Piscitelli; Marco Allarà; Antonio Coluccia; Vincenzo Di Marzo; Giuseppe La Regina; Alessia Ligresti; Ludovica Morera; Ettore Novellino; Romano Silvestri
Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.
Journal of medicinal chemistry 2012;55(11):5627-31.
2011: Antonio Coluccia; Davide Sabbadin; Andrea Brancale
Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
European journal of medicinal chemistry 2011;46(8):3519-25.
2011: Giuseppe La Regina; Antonio Coluccia; Andrea Brancale; Francesco Piscitelli; Valerio Gatti; giovanni maga; Alberta Samuele; Christophe Pannecouque; Dominique Schols; Jan Balzarini; Ettore Novellino; Romano Silvestri
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide.
Journal of medicinal chemistry 2011;54(6):1587-98.
2010: Giuseppe La Regina; Antonio Coluccia; Romano Silvestri
Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors.
Antiviral chemistry & chemotherapy 2010;20(6):213-37.
2009: Giuseppe La Regina; Taradas Sarkar; Ruoli Bai; Michael Edler; Roberto Saletti; Antonio Coluccia; Francesco Piscitelli; Lara Minelli; Valerio Gatti; Carmela Mazzoccoli; Vanessa Palermo; cristina mazzoni; Claudio Falcone; Anna Scovassi; Vincenzo Giansanti; Pietro Campiglia; Amalia Porta; Bruno Maresca; Ernest Hamel; Andrea Brancale; Ettore Novellino; Romano Silvestri
New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies.
Journal of medicinal chemistry 2009;52(23):7512-27.
2007: Giuseppe La Regina; Antonio Coluccia; Francesco Piscitelli; Alberto Bergamini; Anna Sinistro; Antonella Cavazza; giovanni maga; Alberta Samuele; Samantha Zanoli; Ettore Novellino; Marino Artico; Romano Silvestri
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity.
Journal of medicinal chemistry 2007;50(20):5034-8.
2007: Giuseppe La Regina; Michael Edler; Andrea Brancale; Sahar Kandil; Antonio Coluccia; Francesco Piscitelli; Ernest Hamel; Gabriella De Martino; Ruth Matesanz; J Fernando Díaz; Anna Scovassi; Ennio Prosperi; Antonio Lavecchia; Ettore Novellino; Marino Artico; Romano Silvestri
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
Journal of medicinal chemistry 2007;50(12):2865-74.
2007: Rino Ragno; Antonio Coluccia; Giuseppe La Regina; Romano Silvestri
Indolyl aryl sulphones as HIV-1 reverse transcriptase inhibitors: docking and 3D QSAR studies.
Expert opinion on drug discovery 2007;2(1):87-114.
2006: Rino Ragno; Antonio Coluccia; Giuseppe La Regina; Gabriella De Martino; Francesco Piscitelli; Antonio Lavecchia; Ettore Novellino; Alberto Bergamini; Chiara Ciaprini; Anna Sinistro; giovanni maga; Emmanuele Crespan; Marino Artico; Romano Silvestri
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide.
Journal of medicinal chemistry 2006;49(11):3172-84.
2006: Gabriella De Martino; Michael Edler; Giuseppe La Regina; Antonio Coluccia; Maria Chiara Barbera; Denise Barrow; Robert I Nicholson; Gabriela Chiosis; Andrea Brancale; Ernest Hamel; Marino Artico; Romano Silvestri
New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
Journal of medicinal chemistry 2006;49(3):947-54.
2006: Gabriella De Martino; Giuseppe La Regina; Rino Ragno; Antonio Coluccia; Alberto Bergamini; Chiara Ciaprini; Anna Sinistro; giovanni maga; Emmanuele Crespan; Marino Artico; Romano Silvestri
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carboxamide.
Antiviral chemistry & chemotherapy 2006;17(2):59-77.
2005: Rino Ragno; Marino Artico; Gabriella De Martino; Giuseppe La Regina; Antonio Coluccia; Alessandra Di Pasquali; Romano Silvestri
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.
Journal of medicinal chemistry 2005;48(1):213-23.
2004: Gabriella De Martino; Giuseppe La Regina; Antonio Coluccia; Michael Edler; Maria Chiara Barbera; Andrea Brancale; Elizabeth Wilcox; Ernest Hamel; Marino Artico; Romano Silvestri
Arylthioindoles, potent inhibitors of tubulin polymerization.
Journal of medicinal chemistry 2004;47(25):6120-3.