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Manuel Comabella

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Disorders

Chemicals & Drugs

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Óscar Fernández; Juan A García-Merino; Sergio Martínez-Yélamos; Lluís Ramió-Torrentà; Alfredo Rodríguez-Antigüedad; Mar Tintore; Manuel Comabella; Guillermo Izquierdo; José E Meca-Lallana; Celia Oreja-Guevara; José M Prieto; Luisa M Villar; José C Álvarez-Cermeño; Rafael Arroyo-González; Xavier Montalban
[Biomarkers in multiple sclerosis].
S Malhotra; Xavier Montalban; A Vidal-Jordana; Mf Bustamante; J Castilló; Z Castro; Manuel Comabella
SIGLEC1 and SIGLEC7 expression in circulating monocytes of patients with multiple sclerosis.
Manuel Comabella; K Borowski; M F Bustamante; K Rentzsch; Jordi Río; W Stoecker; Xavier Montalban
Treatment with interferon-β does not induce anti-nuclear and anti-neuronal serum autoantibodies in multiple sclerosis patients.

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2013: Óscar Fernández; Juan A García-Merino; Sergio Martínez-Yélamos; Lluís Ramió-Torrentà; Alfredo Rodríguez-Antigüedad; Mar Tintore; Manuel Comabella; Guillermo Izquierdo; José E Meca-Lallana; Celia Oreja-Guevara; José M Prieto; Luisa M Villar; José C Álvarez-Cermeño; Rafael Arroyo-González; Xavier Montalban
[Biomarkers in multiple sclerosis].
Revista de neurologia 2013;56(7):375-90.
2013: S Malhotra; Xavier Montalban; A Vidal-Jordana; Mf Bustamante; J Castilló; Z Castro; Manuel Comabella
SIGLEC1 and SIGLEC7 expression in circulating monocytes of patients with multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2013;19(5):524-31.
2013: Manuel Comabella; K Borowski; M F Bustamante; K Rentzsch; Jordi Río; W Stoecker; Xavier Montalban
Treatment with interferon-β does not induce anti-nuclear and anti-neuronal serum autoantibodies in multiple sclerosis patients.
Journal of neuroimmunology 2013;255(1-2):102-4.
2013: Marta F Bustamante; Xavier Montalban; Ramil N Nurtdinov; Jordi Río; Manuel Comabella
Baseline Gene Expression Signatures in Monocytes from Multiple Sclerosis Patients Treated with Interferon-beta.
PloS one 2013;8(4):e60994.
2013: Antonio Alcina; Iraide Alloza; Alfredo Antigüedad; Rafael Arroyo; Yolanda Blanco; Manuel Comabella; Belén de la Hera; Maria Fedetz; Oscar Fernández; María J Garcia-Barcina; Juan-Antonio García-León; Guillermo Izquierdo; Laura Leyva; Miguel Lucas; Xavier Montalban; Arcadi Navarro; Javier Olascoaga; David Otaegui; Natalia Petit-Marty; Albert Saiz; Elena Urcelay; Koen Vandenbroeck; Jezabel Varade; María Del Mar Abad-Grau; Fuencisla Matesanz
Identification of a functional variant in the KIF5A-CYP27B1-METTL1-FAM119B locus associated with multiple sclerosis.
Journal of medical genetics 2013;50(1):25-33.
2012: Carmen Tur; M José Vicente; Angela Vidal-Jordana; Carlos Nos; Jordi Río; Jaume Sastre-Garriga; Mar Tintoré; M Jesús Arévalo; Georgina Arrambide; Ana Caminero; Joaquín Castilló; Manuel Comabella; Ingrid Galán; Rosalía Horno; Xavier Montalban
Natalizumab discontinuation after PML risk stratification: outcome from a shared and informed decision.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(8):1193-6.
2012: Carme Costa; Manuel Comabella; Xavier Montalban
[Stem cell-based treatment of neurologic diseases].
Medicina clínica 2012;139(5):208-14.
2012: Manuel Comabella; Michael K Racke
New technologies for biomarker discovery in multiple sclerosis.
Journal of neuroimmunology 2012;248(1-2):1.
2012: Alex Sánchez; Ferran Reverter; M Carme Ruíz de Villa; Manuel Comabella
Transcriptomics: mRNA and alternative splicing.
Journal of neuroimmunology 2012;248(1-2):23-31.
2012: Jezabel Varade; Koen Vandenbroeck; Antonio Alcina; Iraide Alloza; Alfredo Antigüedad; Rafael Arroyo; Yolanda Blanco; Manuel Comabella; María Fedetz; Oscar Fernández; María García-Barcina; Carlos López Gómez; Guillermo Izquierdo; Miguel Lucas; Fuencisla Matesanz; Xavier Montalbán; Javier Olascoaga; Miguel A Ortiz; David Otaegui; M Jesús Pinto-Medel; Antonio Catalá Rabasa; Albert Saiz; Elena Urcelay
Replication study of 10 genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CBLB [correction of CLBL] genes.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(7):959-65.
2012: E Cantó; R Arroyo; A Caminero; C Domínguez; O Fernández; Alejandro Horga; G Izquierdo; Fuencisla Matesanz; Xavier Montalban; C Morcillo-Suárez; Arcadi Navarro; J Olascoaga; David Otaegui; F Reverter; A Rodríguez-Antigüedad; Albert Saiz; A Sanchez; Mar Tintoré; E Urcelay; Koen Vandenbroeck; Manuel Comabella
Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(7):983-90.
2012: Oscar Fernandez; Juan A Garcia-Merino; Miguel A Hernandez-Perez; Guillermo Izquierdo; José E Meca-Lallana; Xavier Montalban; Delicias Munoz-Garcia; Javier Olascoaga; Celia Oreja-Guevara; José M Prieto; Lluís Ramio-Torrenta; Alfredo Rodriguez-Antiguedad; Lucía Romero-Pinel; Fernando Sanchez; Nieves Tellez; Mar Tintore; José C Alvarez-Cermeno; Rafael Arroyo-Gonzalez; Luis Brieva; M Carmen Calles-Hernandez; Bonaventura Casanova-Estruch; Manuel Comabella; Virginia de Las Heras
Review of the novelties presented at the 27th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (II).
Revista de neurologia 2012;54(12):734-49.
2012: Óscar Fernández; Juan A García-Merino; Miguel A Hernández-Pérez; Guillermo Izquierdo; José E Meca-Lallana; Xavier Montalban; Delicias Muñoz-García; Javier Olascoaga; Celia Oreja-Guevara; José M Prieto; Lluís Ramió-Torrentà; Alfredo Rodríguez-Antigüedad; Lucía Romero-Pinel; Fernando Sanchez; Nieves Téllez; Mar Tintoré; José C Alvarez-Cermeño; Rafael Arroyo-González; Luis Brieva; M Carmen Calles-Hernández; Bonaventura Casanova-Estruch; Manuel Comabella; Virginia de Las Heras
Review of the novelties presented at the 27th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (I).
Revista de neurologia 2012;54(11):677-91.
2012: Jordi Río; Jaume Sastre-Garriga; M Tintoré; C Tur; J Castilló; Manuel Comabella; C Nos; Xavier Montalban
Change in the clinical activity of multiple sclerosis after treatment switch for suboptimal response.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2012;19(6):899-904.
2012: C Costa; Alejandro Horga; Georgina Arrambide; C Auger; J Castilló; Manuel Comabella; Carlos Nos; Jordi Río; Alex Rovira; Albert Saiz; Jaume Sastre-Garriga; Mar Tintore; C Tur; A Vidal-Jordana; Xavier Montalban
Value of NMO-IgG determination at the time of presentation as CIS.
Neurology 2012;78(20):1608-11.
2012: Manuel Comabella; Kristina Kakalacheva; Xavier Montalban; Christian Münz; Jordi Río; Jan D Lünemann
EBV-specific immune responses in patients with multiple sclerosis responding to IFNβ therapy.
Multiple sclerosis (Houndmills, Basingstoke, England) 2012;18(5):605-9.
2012: A Lopez de Lapuente; Xavier Montalban; Elena Urcelay; Iraide Alloza; A Antigüedad; Rafael Arroyo; Manuel Comabella; Robert Goertsches; U K Zettl; Koen Vandenbroeck
Analysis of the IL28RA locus as genetic risk factor for multiple sclerosis.
Journal of neuroimmunology 2012;245(1-2):98-101.
2012: Iraide Alloza; A Antigüedad; Rafael Arroyo; Y Blanco; Manuel Comabella; A Lopez de Lapuente; Maria Fedetz; O Fernandez; G Izquierdo; Laura Leyva; M Lucas; Fuencisla Matesanz; Xavier Montalban; Concepción Núñez; J Olascoaga; B Oliver-Martos; David Otaegui; A Saiz; Elena Urcelay; Antonio Alcina; Jezabel Varade; Koen Vandenbroeck
ANKRD55 and DHCR7 are novel multiple sclerosis risk loci.
Genes and immunity 2012;13(3):253-7.
2012: Nicolas Fissolo; Victor Llombart; María J Mansilla; Xavier Montalban; Ramil N Nurtdinov; Marta F Bustamante; Carme Costa; Carmen Espejo; Manuel Comabella
Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis.
Journal of neuroinflammation 2012;9():139.
2012: Manuel Comabella; Samia J Khoury
Therapeutic strategies in multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2012;142(1):1.
2012: Koen Vandenbroeck; Antonio Alcina; Iraide Alloza; J Alvarez; A Antigüedad; Rafael Arroyo; Stacy J Caillier; Manuel Comabella; Maria Fedetz; O Fernandez; G Izquierdo; Fuencisla Matesanz; C Matute; X Montalban; J R Oksenberg; M A Ortiz; N Rodriguez-Ezpeleta; B Swaminathan; Elena Urcelay; Ana M Aransay
A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis.
Genes and immunity 2012;13(1):21-8.
2012: Manuel Comabella; Samia J Khoury
Immunopathogenesis of multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2012;142(1):2-8.
2012: Nicolas Fissolo; Xavier Montalban; Manuel Comabella
DNA-based vaccines for multiple sclerosis: current status and future directions.
Clinical immunology (Orlando, Fla.) 2012;142(1):76-83.
2011: Jose E Martínez-Rodríguez; Xavier Montalban; Elvira Munteis; J Rio; Jaume Roquer; Miguel López-Botet; Manuel Comabella
Natural killer cell phenotype and clinical response to interferon-beta therapy in multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2011;141(3):348-56.
2011: Carmen Tur; Jaume Sastre-Garriga; Nieves Téllez; Mar Tintoré; Francesc Xavier Aymerich; Luis Brieva; David Calle; Manuel Comabella; Ingrid Galán; Xavier Montalban; Carlos Nos; Héctor Perkal; Jordi Río; Alex Rovira
Interferon β-1b for the treatment of primary progressive multiple sclerosis: five-year clinical trial follow-up.
Archives of neurology 2011;68(11):1421-7.
2011: S Malhotra; F Martinelli Boneschi; Xavier Montalban; C Morcillo-Suárez; Arcadi Navarro; Jorge R Oksenberg; Jordi Río; A J Sánchez; E Urcelay; Koen Vandenbroeck; U K Zettl; Denis A Akkad; R Alvarez-Lafuente; David Brassat; M F Bustamante; A Chan; J Drulovic; O Fernández; Antonio García-Merino; G Giacalone; Robert Goertsches; J Lechner-Scott; L Leyva; Manuel Comabella
IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis.
Journal of neuroimmunology 2011;239(1-2):101-4.
2011: Marta F Bustamante; Mari Carmen Edo; María Angeles Moro; Carme Costa; Carmen Espejo; Nicolás Fissolo; Ignacio Lizasoain; María José Mansilla; Xavier Montalban; Jordi Río; Manuel Comabella
Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis.
Annals of neurology 2011;70(4):634-45.
2011: Manuel Comabella; Koen Vandenbroeck
Pharmacogenomics and multiple sclerosis: moving toward individualized medicine.
Current neurology and neuroscience reports 2011;11(5):484-91.
2011: Jordi Río; Manuel Comabella; Xavier Montalban
Multiple sclerosis: current treatment algorithms.
Current opinion in neurology 2011;24(3):230-7.
2011: Ana Caminero; Manuel Comabella; Xavier Montalban
Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: an ongoing story.
Journal of neuroimmunology 2011;234(1-2):1-6.
2011: Manuel Comabella
Risk of multiple sclerosis in children with acute demyelination.
Lancet neurology 2011;10(5):399-400.
2011: Alejandro Horga; J Castillo; J Rio; Mar Tintore; C Auger; J Sastre-Garriga; M C Edo; Francisco Carlos Pérez-Miralles; C Tur; Carlos Nos; E Huerga; Manuel Comabella; Alex Rovira; Xavier Montalban
An observational study of the effectiveness and safety of natalizumab in the treatment of multiple sclerosis.
Revista de neurologia 2011;52(6):321-30.
2011: Nicolas Couturier; Florence Bucciarelli; Ramil N Nurtdinov; Marc Debouverie; Christine Lebrun-Frenay; Gilles Defer; Thibault Moreau; Christian Confavreux; Sandra Vukusic; Isabelle Cournu-Rebeix; Robert H Goertsches; Uwe K Zettl; Manuel Comabella; Xavier Montalban; Peter Rieckmann; Frank Weber; Bertram Müller-Myhsok; Gilles Edan; Bertrand Fontaine; Lennart T Mars; Abdelhadi Saoudi; Jorge R Oksenberg; Michel Clanet; Roland S Liblau; David Brassat
Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility.
Brain : a journal of neurology 2011;134(Pt 3):693-703.
2011: Oscar Fernández-Fernández; José C Alvarez-Cermeño; Txomin Arbizu-Urdiain; Rafael Arroyo-González; Carmen Arnal-García; Bonaventura Casanova-Estruch; M Carmen Calles-Hernández; Francisco Coret-Ferrer; Manuel Comabella; Juan A García-Merino; Virginia de Las Heras; Guillermo Izquierdo; José E Meca-Lallana; Delicias Muñoz-García; Javier Olascoaga; Celia Oreja-Guevara; José M Prieto; Alfredo Rodríguez-Antigüedad; Mar Tintoré; Xavier Montalban
[Review of the novelties presented at the 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (I)].
Revista de neurologia 2011;52(4):227-38.
2011: Charlotte E Teunissen; Hayrettin Tumani; Vincent van Pesch; Emmanuelle Waubant; Christian Wolf; Jeffrey L Bennett; Frode S Berven; Lou Brundin; Manuel Comabella; Florian Deisenhammer; Jette L Federiksen; John O Fleming; Diego Franciotta; Roberto Furlan; Gavin Giovannoni; Rogier Q Hintzen; Steven Hughes; Connie R Jimenez; Michael H Johnson; Joep Killestein; Eva Krasulova; Jens Kuhle; Maria Chiara Magnone; Axel Petzold; Cecilia Rajda; Konrad Rejdak; Hollie K Schmidt; Bernhard Hemmer
Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies.
Multiple sclerosis international 2011;2011():246412.
2011: Sunny Malhotra; Xavier Montalban; Lara Nonell; Ramil N Nurtdinov; Francisco Carlos Pérez-Miralles; Jordi Rio; Mari Carmen Ruiz de Villa; Esteban Vegas; Marta F Bustamante; Florian Deisenhammer; Nicolás Fissolo; Manuel Comabella
Search for specific biomarkers of IFNβ bioactivity in patients with multiple sclerosis.
PloS one 2011;6(8):e23634.
2010: Mar Tintore; Alex Rovira; Georgina Arrambide; R Mitjana; Jordi Río; C Auger; Carlos Nos; M C Edo; J Castilló; Alejandro Horga; Francisco Carlos Pérez-Miralles; E Huerga; Manuel Comabella; Jaume Sastre-Garriga; Xavier Montalban
Brainstem lesions in clinically isolated syndromes.
Neurology 2010;75(21):1933-8.
2010: Kristina Kakalacheva; Manuel Comabella
Epstein-Barr virus and multiple sclerosis: causation or association?
Future microbiology 2010;5(11):1617-9.
2010: Montse Camiña-Tato; Carlos Morcillo-Suárez; Marta F Bustamante; Israel Ortega; Arcadi Navarro; Aura Muntasell; Miguel López-Botet; Alex Sánchez; Paco Carmona; Eva Julià; María Teresa Tortola; Laura Audí; Jorge R Oksenberg; Roland Martin; Xavier Montalban; Manuel Comabella
Gender-associated differences of perforin polymorphisms in the susceptibility to multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5392-404.
2010: Koen Vandenbroeck; Manuel Comabella
Single-nucleotide polymorphisms in response to interferon-beta therapy in multiple sclerosis.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2010;30(10):727-32.
2010: Manuel Comabella; Xavier Montalban; Christian Münz; Jan D Lünemann
Targeting dendritic cells to treat multiple sclerosis.
Nature reviews. Neurology 2010;6(9):499-507.
2010: Marta Fernández; Xavier Montalban; Manuel Comabella
Orchestrating innate immune responses in multiple sclerosis: molecular players.
Journal of neuroimmunology 2010;225(1-2):5-12.
2010: Koen Vandenbroeck; Elena Urcelay; Manuel Comabella
IFN-beta pharmacogenomics in multiple sclerosis.
Pharmacogenomics 2010;11(8):1137-48.
2010: Manuel Comabella; Xavier Montalban; Kristina Kakalacheva; Deeqa Osman; Falk Nimmerjahn; Mar Tintoré; Jan D Lünemann
B cell expression of the inhibitory Fc gamma receptor is unchanged in early MS.
Journal of neuroimmunology 2010;223(1-2):135-7.
2010: M Camiña-Tato; M Fernández; C Morcillo-Suárez; Arcadi Navarro; E Julià; M C Edo; Xavier Montalban; Manuel Comabella
Genetic association of CASP8 polymorphisms with primary progressive multiple sclerosis.
Journal of neuroimmunology 2010;222(1-2):70-5.
2010: Jaume Sastre-Garriga; Mar Tintoré; Carlos Nos; C Tur; Jordi Río; Nieves Téllez; J Castilló; Alejandro Horga; H Perkal; Manuel Comabella; Alex Rovira; Xavier Montalban
Clinical features of CIS of the brainstem/cerebellum of the kind seen in MS.
Journal of neurology 2010;257(5):742-6.
2010: Manuel Comabella; Marta Fernández; Roland Martin; Stephanie Rivera-Vallvé; Eva Borrás; Cristina Chiva; Eva Julià; Alex Rovira; Ester Cantó; Jose Carlos Alvarez-Cermeño; Luisa María Villar; Mar Tintoré; Xavier Montalban
Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.
Brain : a journal of neurology 2010;133(Pt 4):1082-93.
2010: Manuel Comabella; Xavier Montalban; Alejandro Horga; B Messmer; K Kakalacheva; T Strowig; E Caballero; C Münz; Jd Lünemann
Antiviral immune response in patients with multiple sclerosis and healthy siblings.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(3):355-8.
2010: Jan D Lünemann; Mar Tintoré; Brady Messmer; Till Strowig; Alex Rovira; Héctor Perkal; Estrella Caballero; Christian Münz; Xavier Montalban; Manuel Comabella
Elevated Epstein-Barr virus-encoded nuclear antigen-1 immune responses predict conversion to multiple sclerosis.
Annals of neurology 2010;67(2):159-69.
2009: Manuel Comabella; J D Lünemann; Jordi Río; Armand Sánchez; C López; E Julià; M Fernández; L Nonell; M Camiña-Tato; F Deisenhammer; E Caballero; M T Tortola; M Prinz; Xavier Montalban; Roland Martin
A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis.
Brain : a journal of neurology 2009;132(Pt 12):3353-65.
2009: Eva Julià; Mari Carmen Edo; Alex Horga; Xavier Montalban; Manuel Comabella
Differential susceptibility to apoptosis of CD4+T cells expressing CCR5 and CXCR3 in patients with MS.
Clinical immunology (Orlando, Fla.) 2009;133(3):364-74.
2009: Manuel Comabella; J M Pradillo; M Fernández; Jordi Río; I Lizasoain; E Julià; M A Moro; J Sastre-Garriga; Xavier Montalban
Plasma levels of 15d-PGJ are not altered in multiple sclerosis.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(11):1197-201.
2009: Jordi Río; Manuel Comabella; Xavier Montalban
Predicting responders to therapies for multiple sclerosis.
Nature reviews. Neurology 2009;5(10):553-60.
2009: M Camiña-Tato; C Morcillo-Suárez; Arcadi Navarro; M Fernández; Alejandro Horga; Xavier Montalban; Manuel Comabella
Genetic association between polymorphisms in the BTG1 gene and multiple sclerosis.
Journal of neuroimmunology 2009;213(1-2):142-7.
2009: Manuel Comabella; David Craig; Carlos Morcillo-Suárez; Jordi Río; Arcadi Navarro; Marta Fernández; Roland Martin; Xavier Montalban
Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.
Archives of neurology 2009;66(8):972-8.
2009: J Río; J Castilló; A Rovira; Mar Tintoré; Jaume Sastre-Garriga; Alejandro Horga; C Nos; Manuel Comabella; X Aymerich; X Montalbán
Measures in the first year of therapy predict the response to interferon beta in MS.
Multiple sclerosis (Houndmills, Basingstoke, England) 2009;15(7):848-53.
2009: Manuel Comabella; M Fernández-Arquero; Jordi Río; A Guinea; M Fernández; M C Cenit; E G de la Concha; Xavier Montalban
HLA class I and II alleles and response to treatment with interferon-beta in relapsing-remitting multiple sclerosis.
Journal of neuroimmunology 2009;210(1-2):116-9.
2009: Koen Vandenbroeck; Manuel Comabella; Eva Tolosa; Robert Goertsches; David Brassat; Rogier Hintzen; Carmen Infante-Duarte; Alexander Favorov; Sergio Escorza; Ricardo Palacios; Jorge R Oksenberg; Pablo Villoslada
United Europeans for development of pharmacogenomics in multiple sclerosis network.
Pharmacogenomics 2009;10(5):885-94.
2009: Manuel Comabella; Carmen Domínguez; J Rio; Pilar Martín-Gallán; A Vilches; N Vilarrasa; Carmen Espejo; Xavier Montalban
Plasma chitotriosidase activity in multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2009;131(2):216-22.
2009: Manuel Comabella; Jordi Río; Carmen Espejo; Mamen Ruiz de Villa; Hammad Al-Zayat; Carlos Nos; Florian Deisenhammer; Sergio E Baranzini; Lara Nonell; Cristina López; Eva Julià; Jorge R Oksenberg; Xavier Montalban
Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis.
Clinical immunology (Orlando, Fla.) 2009;130(2):145-50.
2008: J Río; A Rovira; Mar Tintoré; E Huerga; C Nos; N Tellez; C Tur; Manuel Comabella; X Montalban
Relationship between MRI lesion activity and response to IFN-beta in relapsing-remitting multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(4):479-84.
2008: Robert Goertsches; Sergio E Baranzini; Carlos Morcillo; Carlos Nos; Montse Camiña; Jorge R Oksenberg; Xavier Montalban; Manuel Comabella
Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) 2008;14(3):412-4.
2008: Mar Tintoré; Alex Rovira; Jordi Río; C Tur; Raul Pelayo; Carlos Nos; Nieves Téllez; H Perkal; Manuel Comabella; Jaume Sastre-Garriga; Xavier Montalban
Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?
Neurology 2008;70(13 Pt 2):1079-83.
2008: Esther Byun; Stacy J Caillier; Xavier Montalban; Pablo Villoslada; Oscar Fernández; David Brassat; Manuel Comabella; Joanne Wang; Lisa F Barcellos; Sergio E Baranzini; Jorge R Oksenberg
Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis.
Archives of neurology 2008;65(3):337-44.
2008: Manuel Comabella; David Craig; Montse Camiña-Tato; Carlos Morcillo; Cristina Lopez; Arcadi Navarro; Jordi Rio; Xavier Montalban; Roland Martin
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms.
PloS one 2008;3(10):e3490.
2008: Xinhua Yu; Dirk Koczan; Anna-Maija Sulonen; Denis A Akkad; Antje Kroner; Manuel Comabella; Gianna Costa; Daniela Corongiu; Robert Goertsches; Montserrat Camina-Tato; Hans-Jürgen Thiesen; Harald I Nyland; Sverre Mork; Xavier Montalban; Peter Rieckmann; Maria G Marrosu; Kjell-Morten Myhr; Joerg T Epplen; Janna Saarela; Saleh M Ibrahim
mtDNA nt13708A variant increases the risk of multiple sclerosis.
PloS one 2008;3(2):e1530.
2008: Rachel Farrell; Klaus Bendtzen; Antonio Bertolotto; Berwyn Clark; Manuel Comabella; Florian Deisenhammer; Anna Fogdell-Hahn; Gavin Giovannoni; Hans Peter Hartung; Bernard Hemmer; Jan Hillert; Ludwig Kappos; Joep Killestein; Raija Lindberg; Xavier Montalban; Chris Polman; Per Soelberg Sorensen
Re: Neutralizing antibodies to interferon beta-1b are not associated with disease worsening in multiple sclerosis.
The Journal of international medical research 2008;36(1):204-8; author reply 208-10.
2007: Raul Pelayo; Mar Tintoré; Alex Rovira; Jordi Rio; Carlos Nos; Elisenda Grivé; Nieves Téllez; Manuel Comabella; Xavier Montalban
Polyregional and hemispheric syndromes: a study of these uncommon first attacks in a CIS cohort.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(6):731-6.
2007: Hans-P Hartung; Chris H Polman; Antonio Bertolotto; Florian Deisenhammer; Gavin Giovannoni; Eva Havrdova; Bernhard Hemmer; Jan Hillert; Ludwig Kappos; Bernd C Kieseier; Joep Killestein; Christophe Malcus; Manuel Comabella; Andrew R Pachner; Huub Schellekens; Finn Sellebjerg; Krzysztof Selmaj; Per Soelberg Sorensen
Neutralising antibodies to interferon beta in multiple sclerosis : expert panel report.
Journal of neurology 2007;254(7):827-37.
2007: Manuel Comabella; Roland Martin
Genomics in multiple sclerosis--current state and future directions.
Journal of neuroimmunology 2007;187(1-2):1-8.
2006: Eva Julià; Xavier Montalban; Hammad Al-Zayat; Shohreh Issazadeh-Navikas; Robert Goertsches; Roland Martin; Manuel Comabella
Deficient Fas expression by CD4+ CCR5+ T cells in multiple sclerosis.
Journal of neuroimmunology 2006;180(1-2):147-58.
2006: Mar Tintoré; Alex Rovira; Jordi Río; Carlos Nos; Elisenda Grivé; Nieves Téllez; Raul Pelayo; Manuel Comabella; Jaume Sastre-Garriga; Xavier Montalban
Baseline MRI predicts future attacks and disability in clinically isolated syndromes.
Neurology 2006;67(6):968-72.
2006: Nieves Téllez; Manuel Comabella; Eva Julià; Jordi Río; Mar Tintoré; Luis Brieva; Carlos Nos; Xavier Montalban
Fatigue in progressive multiple sclerosis is associated with low levels of dehydroepiandrosterone.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(4):487-94.
2006: C López; Manuel Comabella; Mar Tintoré; Jaume Sastre-Garriga; X Montalban
Variations in chemokine receptor and cytokine expression during pregnancy in multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 2006;12(4):421-7.
2006: Cristina López; Manuel Comabella; Hammad Al-zayat; Mar Tintoré; Xavier Montalban
Altered maturation of circulating dendritic cells in primary progressive MS patients.
Journal of neuroimmunology 2006;175(1-2):183-91.
2006: Manuel Comabella; Cristina Romera; Montse Camiña; Hector Perkal; Maria Moro; Juan C Leza; ignacio lizasoain; Mireia Castillo; Xavier Montalban
TNF-alpha converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis.
Journal of neurology 2006;253(6):701-6.
2006: Jordi Río; Carlos Nos; Mar Tintoré; Nieves Téllez; Ingrid Galán; Raul Pelayo; Manuel Comabella; Xavier Montalban
Defining the response to interferon-beta in relapsing-remitting multiple sclerosis patients.
Annals of neurology 2006;59(2):344-52.
2005: Tomàs Marquès-Bonet; Oscar Lao; Robert Goertsches; Manuel Comabella; Xavier Montalban; Arcadi Navarro
Association Cluster Detector: a tool for heuristic detection of significance clusters in whole-genome scans.
Bioinformatics (Oxford, England) 2005;21 Suppl 2():ii180-1.
2005: F Purroy García; Manuel Comabella; Nuria Raguer; J Majó; X Montalban
Lambert-Eaton Myasthenic syndrome associated with sarcoidosis.
Journal of neurology 2005;252(9):1127-8.
2005: Robert Goertsches; Manuel Comabella; Arcadi Navarro; Hector Perkal; Xavier Montalban
Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis.
Journal of neuroimmunology 2005;164(1-2):140-7.
2005: Mar Tintoré; Alex Rovira; Jordi Rio; Carlos Nos; Elisenda Grivé; Nieves Téllez; Raul Pelayo; Manuel Comabella; Xavier Montalban
Is optic neuritis more benign than other first attacks in multiple sclerosis?
Annals of neurology 2005;57(2):210-5.
2005: Sergio E Baranzini; Parvin Mousavi; Jordi Rio; Stacy J Caillier; Althea Stillman; Pablo Villoslada; Matthew M Wyatt; Manuel Comabella; Larry D Greller; Roland Somogyi; Xavier Montalban; Jorge R Oksenberg
Transcription-based prediction of response to IFNbeta using supervised computational methods.
PLoS biology 2005;3(1):e2.
2005: Manuel Comabella; Imma Pericot; Robert Goertsches; Carlos Nos; Mireia Castillo; José Blas Navarro; Jordi Río; Xavier Montalban
Plasma osteopontin levels in multiple sclerosis.
Journal of neuroimmunology 2005;158(1-2):231-9.
2004: Manuel Comabella; Laura Altet; Francesc Peris; Pablo Villoslada; Armand Sánchez; Xavier Montalban
Genetic analysis of SLC11A1 polymorphisms in multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 2004;10(6):618-20.
2004: Jaume Sastre-Garriga; Manuel Comabella; Luis Brieva; Alex Rovira; Mar Tintoré; Xavier Montalban
Decreased MMP-9 production in primary progressive multiple sclerosis patients.
Multiple sclerosis (Houndmills, Basingstoke, England) 2004;10(4):376-80.
2004: Jaime Imitola; Manuel Comabella; Anil Chandraker; Fernando Dangond; Mohamed H Sayegh; Evan Y Snyder; Samia J Khoury
Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli.
The American journal of pathology 2004;164(5):1615-25.
2003: Robert Goertsches; Pablo Villoslada; Manuel Comabella; Xavier Montalban; Arcadi Navarro; Emilio G De-la-Concha; Rafael Arroyo; Adolfo Lopez de Munain; David Otaegui; Ricardo Palacios; Jordi Perez-Tur; Aslaug Jonasdottir; Kjartan Benediktsson; Ragnheidur Fossdal; Stephen Sawcer; Efrosini Setakis; Alastair Compston
A genomic screen of Spanish multiple sclerosis patients reveals multiple loci associated with the disease.
Journal of neuroimmunology 2003;143(1-2):124-8.
2003: Jaume Sastre-Garriga; Mar Tintoré; Alex Rovira; Elisenda Grivé; Imma Pericot; Manuel Comabella; A J Thompson; Xavier Montalban
Conversion to multiple sclerosis after a clinically isolated syndrome of the brainstem: cranial magnetic resonance imaging, cerebrospinal fluid and neurophysiological findings.
Multiple sclerosis (Houndmills, Basingstoke, England) 2003;9(1):39-43.
2003: Mar Tintoré; Alex Rovira; Jordi Río; Carlos Nos; Elisenda Grivé; Jaume Sastre-Garriga; Imma Pericot; E Sánchez; Manuel Comabella; Xavier Montalban
New diagnostic criteria for multiple sclerosis: application in first demyelinating episode.
Neurology 2003;60(1):27-30.
2002: Jordi Río; Carlos Nos; Mar Tintoré; Cecilia Borrás; Ingrid Galán; Manuel Comabella; Xavier Montalban
Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: implications for clinical trials.
Annals of neurology 2002;52(4):400-6.
2002: Manuel Comabella; Jaime Imitola; Howard L Weiner; Samia J Khoury
Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients.
Journal of neuroimmunology 2002;126(1-2):205-12.
2001: Karim Makhlouf; Manuel Comabella; Jaime Imitola; Howard L Weiner; Samia J Khoury
Oral salbutamol decreases IL-12 in patients with secondary progressive multiple sclerosis.
Journal of neuroimmunology 2001;117(1-2):156-65.
2001: Manuel Comabella; J S Waye; Nuria Raguer; B Eng; C Domínguez; C Navarro; Cecilia Borrás; William Krivit; Xavier Montalbán
Late-onset metachromatic leukodystrophy clinically presenting as isolated peripheral neuropathy: compound heterozygosity for the IVS2+1G-->A mutation and a newly identified missense mutation (Thr408Ile) in a Spanish family.
Annals of neurology 2001;50(1):108-12.
2000: Konstantin Balashov; Manuel Comabella; T Ohashi; Samia J Khoury; Howard L Weiner
Defective regulation of IFNgamma and IL-12 by endogenous IL-10 in progressive MS.
Neurology 2000;55(2):192-8.
1998: Manuel Comabella; Konstantin Balashov; S Issazadeh; D Smith; Howard L Weiner; Samia J Khoury
Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.
The Journal of clinical investigation 1998;102(4):671-8.