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Suzy Comhair

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Disorders

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Erika L Lundgrin; Donald R Neumann; Margaret M Park; Jacqueline Sharp; W H Wilson Tang; James D Thomas; Rubin M Tuder; Kewal Asosingh; Suzy A A Comhair; Laura Davis; Frank P DiFilippo; Iva Dostanic; Brian B Graham; Serpil C Erzurum
Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year.
Sudakshina Ghosh; Michael Kinter; Sruti Shiva; Belinda Willard; Weiling Xu; kulwant aulak; Suzy A A Comhair; Patricia M DiBello; Serpil C Erzurum
Disulfide bond as a switch for copper-zinc superoxide dismutase activity in asthma.
Fernando Holguin; Elliot Israel; Nizar N Jarjour; Sumita S Khatri; Wendy C Moore; Stephen P Peters; Robert W Powers; W Gerald Teague; Eugene R Bleecker; William W Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Suzy A A Comhair; Serpil C Erzurum; Anne M Fitzpatrick; Benjamin Gaston; Stanley L Hazen; Sally E Wenzel
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype.

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All Publications

2013: Erika L Lundgrin; Donald R Neumann; Margaret M Park; Jacqueline Sharp; W H Wilson Tang; James D Thomas; Rubin M Tuder; Kewal Asosingh; Suzy A A Comhair; Laura Davis; Frank P DiFilippo; Iva Dostanic; Brian B Graham; Serpil C Erzurum
Fasting 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography to detect metabolic changes in pulmonary arterial hypertension hearts over 1 year.
Annals of the American Thoracic Society 2013;10(1):1-9.
2013: Sudakshina Ghosh; Michael Kinter; Sruti Shiva; Belinda Willard; Weiling Xu; kulwant aulak; Suzy A A Comhair; Patricia M DiBello; Serpil C Erzurum
Disulfide bond as a switch for copper-zinc superoxide dismutase activity in asthma.
Antioxidants & redox signaling 2013;18(4):412-23.
2013: Fernando Holguin; Elliot Israel; Nizar N Jarjour; Sumita S Khatri; Wendy C Moore; Stephen P Peters; Robert W Powers; W Gerald Teague; Eugene R Bleecker; William W Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Suzy A A Comhair; Serpil C Erzurum; Anne M Fitzpatrick; Benjamin Gaston; Stanley L Hazen; Sally E Wenzel
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype.
American journal of respiratory and critical care medicine 2013;187(2):153-9.
2012: Lin Wei; Suzy A A Comhair; Serpil C Erzurum; Nicholas S Hill; Ioana R Preston; Kari E Roberts; Rod R Warburton; Barry L Fanburg
Serotonylated fibronectin is elevated in pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology 2012;302(12):L1273-9.
2012: Suzy A A Comhair; Micheala A Aldred; Kewal Asosingh; Lori Mavrakis; Weiling Xu; Serpil C Erzurum
Human primary lung endothelial cells in culture.
American journal of respiratory cell and molecular biology 2012;46(6):723-30.
2012: Samar Farha; Carol Farver; Fred Hsieh; James E Loyd; Margaret Park; Jacqueline Sharp; W H Wilson Tang; Jim Thomas; Kewal Asosingh; Suzy A A Comhair; Serpil C Erzurum
Mast cell number, phenotype, and function in human pulmonary arterial hypertension.
Pulmonary circulation 2012;2(2):220-8.
2012: Nizar N Jarjour; Bruce D Levy; Deborah A Meyers; Wendy C Moore; Stephen P Peters; Ronald L Sorkness; W Gerald Teague; Sally E Wenzel; Eugene R Bleecker; William W Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Suzy A A Comhair; Douglas Curran-Everett; Raed A Dweik; Serpil C Erzurum; Sean B Fain; Anne M Fitzpatrick; Benjamin Gaston; Annette Hastie; Eric A Hoffman; Fernando Holguin; Elliot Israel
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program.
American journal of respiratory and critical care medicine 2012;185(4):356-62.
2011: Heng T Duong; Serpil C Erzurum; Lori Mavrakis; Benjamin M Savasky; Micheala A Aldred; Suzy A A Comhair; Kewal Asosingh
Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension.
Pulmonary circulation 2011;1(4):475-86.
2011: Ilka Decker; Suzy A A Comhair; Samar Farha; Sudakshina Ghosh; Alan E Lichtin; Margaret Park; Wai Hong Wilson Tang; Sihe Wang; Serpil C Erzurum
High levels of zinc-protoporphyrin identify iron metabolic abnormalities in pulmonary arterial hypertension.
Clinical and translational science 2011;4(4):253-8.
2011: Samuel H Wedes; Weijia Wu; Karen M McDowell; Suzy A A Comhair; Joseph A DiDonato; Serpil C Erzurum; Stanley L Hazen
Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children.
The Journal of pediatrics 2011;159(2):248-55.e1.
2011: Silvana Balzar; Merritt L Fajt; Suzy A A Comhair; Serpil C Erzurum; Eugene Bleecker; William W Busse; Mario Castro; Benjamin Gaston; Elliot Israel; Lawrence B Schwartz; Douglas Curran-Everett; Charity G Moore; Sally E Wenzel
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program.
American journal of respiratory and critical care medicine 2011;183(3):299-309.
2011: Suzy A A Comhair; Douglas Curran-Everett; Raed A Dweik; Serpil C Erzurum; Benjamin Gaston; Jeffrey Hammel; Stanley L Hazen; Elliot Israel; W Nizar Jarjour; Deborah Meyers; Wendy Moore; Stephen P Peters; Kristin S Ricci; W Gerald Teague; Sally Wenzel; Elizabeth J Ampleford; Eugene R Bleecker; William W Busse; William J Calhoun; Mario Castro; Kian Fan Chung
Detrimental effects of environmental tobacco smoke in relation to asthma severity.
PloS one 2011;6(5):e18574.
2010: Raed A Dweik; Ronald L Sorkness; Sally Wenzel; Jeffrey P Hammel; Douglas Curran-Everett; Suzy A A Comhair; Eugene Bleecker; William Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Elliot Israel; Nizar N Jarjour; Wendy Moore; Stephen Peters; Gerald Teague; Benjamin Gaston; Serpil C Erzurum
Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma.
American journal of respiratory and critical care medicine 2010;181(10):1033-41.
2010: IWONA FIJALKOWSKA-GORZKA; Weiling Xu; Suzy A A Comhair; Allison J Janocha; Lori A Mavrakis; Balaji Krishnamachary; Lijie Zhen; Thianzi Mao; Amy Richter; Serpil C Erzurum; Rubin M Tuder
Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells.
The American journal of pathology 2010;176(3):1130-8.
2010: Wendy C Moore; Deborah A Meyers; Sally E Wenzel; W Gerald Teague; Huashi Li; Xingnan Li; Ralph D'Agostino; Mario Castro; Douglas Curran-Everett; Anne M Fitzpatrick; Benjamin Gaston; Nizar N Jarjour; Ronald Sorkness; William J Calhoun; Kian Fan Chung; Suzy A A Comhair; Raed A Dweik; Elliot Israel; Stephen P Peters; William W Busse; Serpil C Erzurum; Eugene R Bleecker
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
American journal of respiratory and critical care medicine 2010;181(4):315-23.
2010: Suzy A A Comhair; Serpil C Erzurum
Redox control of asthma: molecular mechanisms and therapeutic opportunities.
Antioxidants & redox signaling 2010;12(1):93-124.
2009: Arnaud Chambellan; Rachel Leahy; Weiling Xu; Paul J Cruickshank; Allison Janocha; Katalin Szabo; Steven B Cannady; Suzy A A Comhair; Serpil C Erzurum
Pivotal role of c-Fos in nitric oxide synthase 2 expression in airway epithelial cells.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2009;20(3):143-9.
2009: Samuel H Wedes; Sumita B Khatri; Renliang Zhang; Weijia Wu; Suzy A A Comhair; Sally Wenzel; W Gerald Teague; Elliot Israel; Serpil C Erzurum; Stanley L Hazen
Noninvasive markers of airway inflammation in asthma.
Clinical and translational science 2009;2(2):112-7.
2009: Mark E Lauer; Csaba Fulop; Durba Mukhopadhyay; Suzy A A Comhair; Serpil C Erzurum; Vincent C Hascall
Airway smooth muscle cells synthesize hyaluronan cable structures independent of inter-alpha-inhibitor heavy chain attachment.
The Journal of biological chemistry 2009;284(8):5313-23.
2008: metin aytekin; Suzy A A Comhair; Carol de la Motte; Sudip K Bandyopadhyay; Carol Farver; Vincent C Hascall; Serpil C Erzurum; raed dweik
High levels of hyaluronan in idiopathic pulmonary arterial hypertension.
American journal of physiology. Lung cellular and molecular physiology 2008;295(5):L789-99.
2008: Abigail Lara; Sumita B Khatri; Zeneng Wang; Suzy A A Comhair; Weiling Xu; raed dweik; Melanie Bodine; Bruce S Levison; Jeffrey Hammel; Eugene R Bleecker; William Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Douglas Curran-Everett; Benjamin Gaston; Elliot Israel; Nizar Jarjour; Wendy Moore; Stephen P Peters; W Gerald Teague; Sally E Wenzel; Stanley L Hazen; Serpil C Erzurum
Alterations of the arginine metabolome in asthma.
American journal of respiratory and critical care medicine 2008;178(7):673-81.
2008: Fares A Masri; Suzy A A Comhair; Iva Dostanic-Larson; Francisco Takao Kaneko; Raed A Dweik; Alejandro C Arroliga; Serpil C Erzurum
Deficiency of lung antioxidants in idiopathic pulmonary arterial hypertension.
Clinical and translational science 2008;1(2):99-106.
2008: Kewal Asosingh; Micheala A Aldred; Amit Vasanji; Judith A Drazba; Jacqueline Sharp; Carol Farver; Suzy A A Comhair; Weiling Xu; Lauren Licina; Lan Huang; Bela Anand-Apte; Mervin C Yoder; Rubin M Tuder; Serpil C Erzurum
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension.
The American journal of pathology 2008;172(3):615-27.
2008: Emanuela Masini; Lucia Giannini; Silvia Nistri; Lorenzo Cinci; Rosanna Mastroianni; Wei Xu; Suzy A A Comhair; Dechun Li; Salvatore Cuzzocrea; George M Matuschak; Daniela Salvemini
Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation.
The Journal of pharmacology and experimental therapeutics 2008;324(2):548-57.
2007: Steven B Cannady; Pete S Batra; Rachel Leahy; Martin J Citardi; Allison J Janocha; Kristin Ricci; Suzy A A Comhair; Melanie Bodine; Zeneng Wang; Stanley L Hazen; Serpil C Erzurum
Signal transduction and oxidative processes in sinonasal polyposis.
The Journal of allergy and clinical immunology 2007;120(6):1346-53.
2007: Fares A Masri; Weiling Xu; Suzy A A Comhair; Kewal Asosingh; Michelle Koo; Amit Vasanji; Judith A Drazba; Bela Anand-Apte; Serpil C Erzurum
Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension.
American journal of physiology. Lung cellular and molecular physiology 2007;293(3):L548-54.
2006: Arnaud Chambellan; Paul J Cruickshank; Patrick McKenzie; Steven B Cannady; Katalin Szabo; Suzy A A Comhair; Serpil C Erzurum
Gene expression profile of human airway epithelium induced by hyperoxia in vivo.
American journal of respiratory cell and molecular biology 2006;35(4):424-35.
2006: Weiling Xu; Shuo Zheng; Tannishia Goggans; Patti Kiser; Miguel E Quinones-Mateu; Allison J Janocha; Suzy A A Comhair; Roger Slee; Bryan R G Williams; Serpil C Erzurum
Cystic fibrosis and normal human airway epithelial cell response to influenza a viral infection.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006;26(9):609-27.
2006: Tobias Peikert; Ulrich Specks; Carol Farver; Serpil C Erzurum; Suzy A A Comhair
Melanoma antigen A4 is expressed in non-small cell lung cancers and promotes apoptosis.
Cancer research 2006;66(9):4693-700.
2006: Sudakshina Ghosh; Allison J Janocha; Mark A Aronica; Shadi Swaidani; Suzy A A Comhair; Weiling Xu; Lemin Zheng; Suma Kaveti; Michael Kinter; Stanley L Hazen; Serpil C Erzurum
Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(9):5587-97.
2005: Fares A Masri; Suzy A A Comhair; Thomas Koeck; Weiling Xu; Allison J Janocha; Sudakshina Ghosh; raed dweik; Joseph A Golish; Michael Kinter; Dennis J Stuehr; Serpil C Erzurum; kulwant aulak
Abnormalities in nitric oxide and its derivatives in lung cancer.
American journal of respiratory and critical care medicine 2005;172(5):597-605.
2005: Emanuela Masini; Daniele Bani; Alfredo Vannacci; Simone Pierpaoli; Pier Francesco Mannaioni; Suzy A A Comhair; Weiling Xu; Carolina Muscoli; Serpil C Erzurum; Daniela Salvemini
Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic.
Free radical biology & medicine 2005;39(4):520-31.
2005: Suzy A A Comhair; Kristin S Ricci; Mercedes E Arroliga; Abigail R Lara; raed dweik; Wei Song; Stanley L Hazen; Eugene R Bleecker; William W Busse; K Fan Chung; Benjamin Gaston; Annette Hastie; Mark Hew; Nizar N Jarjour; Wendy Moore; Stephen Peters; W Gerald Teague; Sally E Wenzel; Serpil C Erzurum
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma.
American journal of respiratory and critical care medicine 2005;172(3):306-13.
2005: Suzy A A Comhair; Weiling Xu; Sudakshina Ghosh; Frederik B J M Thunnissen; alex almasan; William J Calhoun; Allison J Janocha; Lemin Zheng; Stanley L Hazen; Serpil C Erzurum
Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity.
The American journal of pathology 2005;166(3):663-74.
2005: Suzy A A Comhair; Serpil C Erzurum
The regulation and role of extracellular glutathione peroxidase.
Antioxidants & redox signaling 2005;7(1-2):72-9.
2004: Weiling Xu; F Takao Kaneko; Shuo Zheng; Suzy A A Comhair; Allison J Janocha; Tannishia Goggans; Frederik B J M Thunnissen; Carol Farver; Stanley L Hazen; Constance Jennings; raed dweik; Alejandro C Arroliga; Serpil C Erzurum
Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1746-8.
2003: Athena A Andreadis; Stanley L Hazen; Suzy A A Comhair; Serpil C Erzurum
Oxidative and nitrosative events in asthma.
Free radical biology & medicine 2003;35(3):213-25.
2003: Weiling Xu; Suzy A A Comhair; Shuo Zheng; Shan C Chu; Joanna Marks-Konczalik; Joel Moss; S Jaharul Haque; Serpil C Erzurum
STAT-1 and c-Fos interaction in nitric oxide synthase-2 gene activation.
American journal of physiology. Lung cellular and molecular physiology 2003;285(1):L137-48.
2003: Shuo Zheng; Bishnu P De; Suresh Choudhary; Suzy A A Comhair; Tannishia Goggans; Roger Slee; Bryan R G Williams; Joseph M Pilewski; S Jaharul Haque; Serpil C Erzurum
Impaired innate host defense causes susceptibility to respiratory virus infections in cystic fibrosis.
Immunity 2003;18(5):619-30.
2002: Suzy A A Comhair; Serpil C Erzurum
Antioxidant responses to oxidant-mediated lung diseases.
American journal of physiology. Lung cellular and molecular physiology 2002;283(2):L246-55.
2001: J Chung-man Ho; S Zheng; Suzy A A Comhair; Carol Farver; Serpil C Erzurum
Differential expression of manganese superoxide dismutase and catalase in lung cancer.
Cancer research 2001;61(23):8578-85.
2001: J C MacPherson; Suzy A A Comhair; Serpil C Erzurum; donald klein; M F Lipscomb; mani kavuru; M K Samoszuk; Stanley L Hazen
Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(9):5763-72.
2001: raed dweik; Suzy A A Comhair; Benjamin Gaston; Frederik B J M Thunnissen; Carol Farver; Mary Jane Thomassen; mani kavuru; Jeffrey P Hammel; Husam M Abu-Soud; Serpil C Erzurum
NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2622-7.
2001: Suzy A A Comhair; PR Bhathena; Carol Farver; Frederik B J M Thunnissen; Serpil C Erzurum
Extracellular glutathione peroxidase induction in asthmatic lungs: evidence for redox regulation of expression in human airway epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):70-78.
2000: Suzy A A Comhair; Mary Jane Thomassen; Serpil C Erzurum
Differential induction of extracellular glutathione peroxidase and nitric oxide synthase 2 in airways of healthy individuals exposed to 100% O(2) or cigarette smoke.
American journal of respiratory cell and molecular biology 2000;23(3):350-4.
2000: FH Guo; Suzy A A Comhair; Shuo Zheng; raed dweik; N Tony Eissa; Mary Jane Thomassen; William J Calhoun; Serpil C Erzurum
Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5970-80.
2000: Weijia Wu; M K Samoszuk; Suzy A A Comhair; Mary Jane Thomassen; Carol Farver; raed dweik; mani kavuru; Serpil C Erzurum; Stanley L Hazen
Eosinophils generate brominating oxidants in allergen-induced asthma.
The Journal of clinical investigation 2000;105(10):1455-63.
2000: Suzy A A Comhair; PR Bhathena; raed dweik; mani kavuru; Serpil C Erzurum
Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response.
Lancet 2000;355(9204):624.
2000: PR Bhathena; Suzy A A Comhair; K J Holroyd; Serpil C Erzurum
Interleukin-9 receptor expression in asthmatic airways In vivo.
Lung 2000;178(3):149-60.
1999: Nandan Bhattacharyya; Huan-Chao Chen; Suzy A A Comhair; S C Erzurum; Spira Banerjee
Variant forms of DNA polymerase beta in primary lung carcinomas.
DNA and cell biology 1999;18(7):549-54.
1999: Suzy A A Comhair; M J Lewis; PR Bhathena; Jeffrey P Hammel; Serpil C Erzurum
Increased glutathione and glutathione peroxidase in lungs of individuals with chronic beryllium disease.
American journal of respiratory and critical care medicine 1999;159(6):1824-9.
1998: F T Kaneko; Alejandro C Arroliga; raed dweik; Suzy A A Comhair; Daniel Laskowski; R Oppedisano; Mary Jane Thomassen; Serpil C Erzurum
Biochemical reaction products of nitric oxide as quantitative markers of primary pulmonary hypertension.
American journal of respiratory and critical care medicine 1998;158(3):917-23.