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Ronald Conaway

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Chemicals & Drugs

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Kuang-Lei Tsai; Joan W Conaway; Ronald C Conaway; Shigeo Sato; Chieri Tomomori-Sato; Francisco J Asturias
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.
Chieri Tomomori-Sato; Ronald C Conaway; Shigeo Sato; Joan Weliky Conaway
Immunoaffinity purification of protein complexes from Mammalian cells.
Ronald C Conaway; Joan Weliky Conaway
The Mediator complex and transcription elongation.

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All Publications

2013: Kuang-Lei Tsai; Joan W Conaway; Ronald C Conaway; Shigeo Sato; Chieri Tomomori-Sato; Francisco J Asturias
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.
Nature structural & molecular biology 2013;20(5):611-9.
2013: Chieri Tomomori-Sato; Ronald C Conaway; Shigeo Sato; Joan Weliky Conaway
Immunoaffinity purification of protein complexes from Mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2013;977():273-87.
2013: Ronald C Conaway; Joan Weliky Conaway
The Mediator complex and transcription elongation.
Biochimica et biophysica acta 2013;1829(1):69-75.
2012: Dotan Sela; Michael P Washburn; Lu Chen; Joan Weliky Conaway; Laurence Florens; Skylar A Martin-Brown; Ronald C Conaway
Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes.
The Journal of biological chemistry 2012;287(27):23035-45.
2011: Ronald C Conaway; Joan Weliky Conaway
Origins and activity of the Mediator complex.
Seminars in cell & developmental biology 2011;22(7):729-34.
2011: Hidehisa Takahashi; Chieri Tomomori-Sato; Michael Washburn; Charles A S Banks; Ronald C Conaway; Laurence Florens; Stephanie E Kong; Chengqi Lin; Skylar A Martin-Brown; Tari J Parmely; Shigeo Sato; Chris W Seidel; Ali Shilatifard; Edwin R Smith; Selene K Swanson; Henrietta Szutorisz; Joan Weliky Conaway
Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
Cell 2011;146(1):92-104.
2011: Ronald C Conaway; Joan Weliky Conaway
Function and regulation of the Mediator complex.
Current opinion in genetics & development 2011;21(2):225-30.
2010: Chengqi Lin; Edwin R Smith; Hidehisa Takahashi; Ka Chun Lai; Skylar Martin-Brown; Laurence Florens; Michael P Washburn; Joan W Conaway; Ronald C Conaway; Ali Shilatifard
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Molecular cell 2010;37(3):429-37.
2010: Yong Cai; Jingji Jin; Selene K Swanson; Michael D Cole; Seung Hyuk Choi; Laurence Florens; Michael Washburn; Joan Weliky Conaway; Ronald C Conaway
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
The Journal of biological chemistry 2010;285(7):4268-72.
2009: Ronald C Conaway; Joan Weliky Conaway
Mediator comes out from the shadows.
Structure (London, England : 1993) 2009;17(4):485-6.
2009: Ronald C Conaway; Joan Weliky Conaway
The INO80 chromatin remodeling complex in transcription, replication and repair.
Trends in biochemical sciences 2009;34(2):71-7.
2009: Ning Ding; Chieri Tomomori-Sato; Shigeo Sato; Ronald C Conaway; Joan Weliky Conaway; Thomas Boyer
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.
The Journal of biological chemistry 2009;284(5):2648-56.
2008: Tingting Yao; Ling Song; Jingji Jin; Yong Cai; Hidehisa Takahashi; Selene K Swanson; Michael Washburn; Laurence Florens; Ronald C Conaway; Robert E Cohen; Joan Weliky Conaway
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex.
Molecular cell 2008;31(6):909-17.
2008: Nawel Mahrour; William B Redwine; Laurence Florens; Selene K Swanson; Skylar A Martin-Brown; William D Bradford; Karen Staehling-Hampton; Michael Washburn; Ronald C Conaway; Joan Weliky Conaway
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
The Journal of biological chemistry 2008;283(12):8005-13.
2008: Evangelia Koutelou; Shigeo Sato; Chieri Tomomori-Sato; Laurence Florens; Selene K Swanson; Michael Washburn; Maria Kokkinaki; Ronald C Conaway; Joan Weliky Conaway; Nicholas K Moschonas
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.
The Journal of biological chemistry 2008;283(7):3846-53.
2008: Mihaela E Sardiu; Yong Cai; Jingji Jin; Selene K Swanson; Ronald C Conaway; Joan Weliky Conaway; Laurence Florens; Michael Washburn
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1454-9.
2007: Yong Cai; Jingji Jin; Tingting Yao; Aaron J Gottschalk; Selene K Swanson; Su Wu; Yang Shi; Michael Washburn; Laurence Florens; Ronald C Conaway; Joan Weliky Conaway
YY1 functions with INO80 to activate transcription.
Nature structural & molecular biology 2007;14(9):872-4.
2007: Charles A S Banks; Stephanie E Kong; Henrik Spahr; Laurence Florens; Skylar A Martin-Brown; Michael Washburn; Joan Weliky Conaway; Arcady Mushegian; Ronald C Conaway
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL.
The Journal of biological chemistry 2007;282(8):5761-9.
2006: Andrew C Paoletti; Tari J Parmely; Chieri Tomomori-Sato; Shigeo Sato; Dongxiao Zhu; Ronald C Conaway; Joan Weliky Conaway; Laurence Florens; Michael Washburn
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):18928-33.
2006: Yong Cai; Jingji Jin; Aaron J Gottschalk; Tingting Yao; Joan Weliky Conaway; Ronald C Conaway
Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes.
Methods (San Diego, Calif.) 2006;40(4):312-7.
2006: Nicolas Charlet-Berguerand; Sascha Feuerhahn; Stephanie E Kong; Howard Ziserman; Joan Weliky Conaway; Ronald C Conaway; Jean-Marc Egly
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.
The EMBO journal 2006;25(23):5481-91.
2006: Tingting Yao; Ling Song; Wei Xu; George N DeMartino; Laurence Florens; Selene K Swanson; Michael Washburn; Ronald C Conaway; Joan Weliky Conaway; Robert E Cohen
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1.
Nature cell biology 2006;8(9):994-1002.
2005: Jingji Jin; Yong Cai; Tingting Yao; Aaron J Gottschalk; Laurence Florens; Selene K Swanson; José L Gutiérrez; Michael K Coleman; Jerry L Workman; Arcady Mushegian; Michael Washburn; Ronald C Conaway; Joan Weliky Conaway
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex.
The Journal of biological chemistry 2005;280(50):41207-12.
2005: Jingji Jin; Yong Cai; Bing Li; Ronald C Conaway; Jerry L Workman; Joan Weliky Conaway; Thomas Kusch
In and out: histone variant exchange in chromatin.
Trends in biochemical sciences 2005;30(12):680-7.
2005: Stephanie E Kong; Charles A S Banks; Ali Shilatifard; Joan Weliky Conaway; Ronald C Conaway
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10094-8.
2005: Ronald C Conaway; Shigeo Sato; Chieri Tomomori-Sato; Tingting Yao; Joan Weliky Conaway
The mammalian Mediator complex and its role in transcriptional regulation.
Trends in biochemical sciences 2005;30(5):250-5.
2005: Yong Cai; Jingji Jin; Laurence Florens; Selene K Swanson; Thomas Kusch; Bing Li; Jerry L Workman; Michael Washburn; Ronald C Conaway; Joan Weliky Conaway
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.
The Journal of biological chemistry 2005;280(14):13665-70.
2005: Mélina L Heuzé; Florence C Guibal; Charles A S Banks; Joan Weliky Conaway; Ronald C Conaway; Yvon E Cayre; Arndt Benecke; Pierre G Lutz
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.
The Journal of biological chemistry 2005;280(7):5468-74.
2005: Joan Weliky Conaway; Laurence Florens; Shigeo Sato; Chieri Tomomori-Sato; Tari J Parmely; Tingting Yao; Selene K Swanson; Charles A S Banks; Michael Washburn; Ronald C Conaway
The mammalian Mediator complex.
FEBS letters 2005;579(4):904-8.
2004: Takumi Kamura; Katsumi Maenaka; Shuhei Kotoshiba; Masaki Matsumoto; Daisuke Kohda; Ronald C Conaway; Joan Weliky Conaway; Keiichi I Nakayama
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Genes & development 2004;18(24):3055-65.
2004: Paola Blanchette; Chi Ying Cheng; Qin Yan; Gary Ketner; David A Ornelles; Thomas Dobner; Ronald C Conaway; Joan Weliky Conaway; Philip E Branton
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.
Molecular and cellular biology 2004;24(21):9619-29.
2004: Qin Yan; Takumi Kamura; Yong Cai; Jingji Jin; Mircea Ivan; Arcady Mushegian; Ronald C Conaway; Joan Weliky Conaway
Identification of Elongin C and Skp1 sequences that determine Cullin selection.
The Journal of biological chemistry 2004;279(41):43019-26.
2004: Shigeo Sato; Chieri Tomomori-Sato; Tari J Parmely; Laurence Florens; Boris Zybailov; Selene K Swanson; Charles A S Banks; Jingji Jin; Yong Cai; Michael Washburn; Joan Weliky Conaway; Ronald C Conaway
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.
Molecular cell 2004;14(5):685-91.
2004: Chieri Tomomori-Sato; Shigeo Sato; Tari J Parmely; Charles A S Banks; Irina Sorokina; Laurence Florens; Boris Zybailov; Michael Washburn; Christopher S Brower; Ronald C Conaway; Joan Weliky Conaway
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
The Journal of biological chemistry 2004;279(7):5846-51.
2003: Shigeo Sato; Chieri Tomomori-Sato; Charles A S Banks; Tari J Parmely; Irina Sorokina; Christopher S Brower; Ronald C Conaway; Joan Weliky Conaway
A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.
The Journal of biological chemistry 2003;278(50):49671-4.
2003: Yong Cai; Jingji Jin; Chieri Tomomori-Sato; Shigeo Sato; Irina Sorokina; Tari J Parmely; Ronald C Conaway; Joan Weliky Conaway
Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.
The Journal of biological chemistry 2003;278(44):42733-6.
2003: Ronald C Conaway; Stephanie E Kong; Joan Weliky Conaway
TFIIS and GreB: two like-minded transcription elongation factors with sticky fingers.
Cell 2003;114(3):272-4.
2003: Shigeo Sato; Chieri Tomomori-Sato; Charles A S Banks; Irina Sorokina; Tari J Parmely; Stephanie E Kong; Jingji Jin; Yong Cai; William Stratton Lane; Christopher S Brower; Ronald C Conaway; Joan Weliky Conaway
Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3.
The Journal of biological chemistry 2003;278(17):15123-7.
2003: Mindy A Maynard; Heng Qi; Jacky Chung; Eric H L Lee; Yukihiro Kondo; Shuntaro Hara; Ronald C Conaway; Joan Weliky Conaway; Michael Ohh
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.
The Journal of biological chemistry 2003;278(13):11032-40.
2003: Stephanie E Kong; Ali Shilatifard; Ronald C Conaway; Joan Weliky Conaway
Preparation and assay of RNA polymerase II elongation factors elongin and ELL.
Methods in enzymology 2003;371():276-83.
2003: Arik Dvir; Joan Weliky Conaway; Ronald C Conaway
Assays for investigating the mechanism of promoter escape by RNA polymerase II.
Methods in enzymology 2003;370():733-40.
2002: Mircea Ivan; Thomas Haberberger; David C Gervasi; Kristen S Michelson; Volkmar Günzler; Keiichi Kondo; Haifeng Yang; Irina Sorokina; Ronald C Conaway; Joan Weliky Conaway; William G Kaelin
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13459-64.
2002: Takumi Kamura; Christopher S Brower; Ronald C Conaway; Joan Weliky Conaway
A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
The Journal of biological chemistry 2002;277(33):30388-93.
2002: Christopher S Brower; Shigeo Sato; Chieri Tomomori-Sato; Takumi Kamura; Arnim Pause; Robert Stearman; Richard D Klausner; Sohail Malik; William Stratton Lane; Irina Sorokina; Robert G Roeder; Joan Weliky Conaway; Ronald C Conaway
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10353-8.
2002: Ronald C Conaway; Christopher S Brower; Joan Weliky Conaway
Emerging roles of ubiquitin in transcription regulation.
Science (New York, N.Y.) 2002;296(5571):1254-8.
2002: Ning Zheng; Brenda A Schulman; Langzhou Song; Julie J Miller; Philip Jeffrey; Ping Wang; Claire Chu; Deanna M Koepp; Stephen J Elledge; Michele Pagano; Ronald C Conaway; Joan Weliky Conaway; J Wade Harper; Nikola P Pavletich
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Nature 2002;416(6882):703-9.
2002: Takumi Kamura; Joan Weliky Conaway; Ronald C Conaway
Roles of SCF and VHL ubiquitin ligases in regulation of cell growth.
Progress in molecular and subcellular biology 2002;29():1-15.
2001: E Querido; Paola Blanchette; Qin Yan; Takumi Kamura; M Morrison; Diane B Boivin; William G Kaelin; Ronald C Conaway; Joan Weliky Conaway; Philip E Branton
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex.
Genes & development 2001;15(23):3104-17.
2001: Takumi Kamura; D Burian; Qin Yan; SL Schmidt; William Stratton Lane; E Querido; Philip E Branton; Ali Shilatifard; Ronald C Conaway; Joan Weliky Conaway
Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
The Journal of biological chemistry 2001;276(32):29748-53.
2001: B J Elmendorf; Ali Shilatifard; Qin Yan; Joan Weliky Conaway; Ronald C Conaway
Transcription factors TFIIF, ELL, and Elongin negatively regulate SII-induced nascent transcript cleavage by non-arrested RNA polymerase II elongation intermediates.
The Journal of biological chemistry 2001;276(25):23109-14.
2001: Takumi Kamura; D Burian; H Khalili; SL Schmidt; Sanai Sato; W J Liu; Michael N Conrad; Ronald C Conaway; Joan Weliky Conaway; Ali Shilatifard
Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose.
The Journal of biological chemistry 2001;276(19):16528-33.
2001: L Spangler; X Wang; Joan Weliky Conaway; Ronald C Conaway; Arik Dvir
TFIIH action in transcription initiation and promoter escape requires distinct regions of downstream promoter DNA.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5544-9.
2001: Arik Dvir; Joan Weliky Conaway; Ronald C Conaway
Mechanism of transcription initiation and promoter escape by RNA polymerase II.
Current opinion in genetics & development 2001;11(2):209-14.
2000: Takumi Kamura; S Sato; K Iwai; Maria F Czyzyk-Krzeska; Ronald C Conaway; Joan Weliky Conaway
Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10430-5.
2000: Joan Weliky Conaway; Ali Shilatifard; Arik Dvir; Ronald C Conaway
Control of elongation by RNA polymerase II.
Trends in biochemical sciences 2000;25(8):375-80.
2000: Joan Weliky Conaway; Ronald C Conaway
Structural biology. Light at the end of the channel.
Science (New York, N.Y.) 2000;288(5466):632-3.
2000: Christopher M Koth; Maria-Victoria Botuyan; Rodney Moreland; David B Jansma; Joan Weliky Conaway; Ronald C Conaway; Walter J Chazin; James D Friesen; Cheryl H Arrowsmith; Aled M Edwards
Elongin from Saccharomyces cerevisiae.
The Journal of biological chemistry 2000;275(15):11174-80.
1999: Qin Yan; Rodney Moreland; Joan Weliky Conaway; Ronald C Conaway
Dual roles for transcription factor IIF in promoter escape by RNA polymerase II.
The Journal of biological chemistry 1999;274(50):35668-75.
1999: Michael Ohh; Y Takagi; T Aso; CE Stebbins; Nikola P Pavletich; B Zbar; Ronald C Conaway; Joan Weliky Conaway; William G Kaelin
Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein.
The Journal of clinical investigation 1999;104(11):1583-91.
1999: Takumi Kamura; Michael N Conrad; Qin Yan; Ronald C Conaway; Joan Weliky Conaway
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
Genes & development 1999;13(22):2928-33.
1999: Kazuhiro Iwai; Koji Yamanaka; Takumi Kamura; Nagahiro Minato; Ronald C Conaway; Joan Weliky Conaway; Richard D Klausner; Arnim Pause
Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12436-41.
1999: Rodney Moreland; F Tirode; Qin Yan; Joan Weliky Conaway; Jean-Marc Egly; Ronald C Conaway
A role for the TFIIH XPB DNA helicase in promoter escape by RNA polymerase II.
The Journal of biological chemistry 1999;274(32):22127-30.
1999: Maria-Victoria Botuyan; Christopher M Koth; Georges Mer; Avijit Chakrabartty; Joan Weliky Conaway; Ronald C Conaway; Aled M Edwards; Cheryl H Arrowsmith; Walter J Chazin
Binding of elongin A or a von Hippel-Lindau peptide stabilizes the structure of yeast elongin C.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9033-8.
1999: Daniel Reines; Ronald C Conaway; Joan Weliky Conaway
Mechanism and regulation of transcriptional elongation by RNA polymerase II.
Current opinion in cell biology 1999;11(3):342-6.
1999: Christopher S Brower; Ali Shilatifard; T Mather; Takumi Kamura; Y Takagi; D Haque; A Treharne; SI Foundling; Joan Weliky Conaway; Ronald C Conaway
The elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C.
The Journal of biological chemistry 1999;274(19):13629-36.
1999: Dorota Skowyra; Deanna M Koepp; Takumi Kamura; Michael N Conrad; Ronald C Conaway; Joan Weliky Conaway; Stephen J Elledge; J Wade Harper
Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Science (New York, N.Y.) 1999;284(5414):662-5.
1999: Takumi Kamura; Deanna M Koepp; Michael N Conrad; Dorota Skowyra; Rodney Moreland; O Iliopoulos; William Stratton Lane; William G Kaelin; Stephen J Elledge; Ronald C Conaway; J Wade Harper; Joan Weliky Conaway
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Science (New York, N.Y.) 1999;284(5414):657-61.
1999: Joan Weliky Conaway; Ronald C Conaway
Transcription elongation and human disease.
Annual review of biochemistry 1999;68():301-19.
1998: Takumi Kamura; S Sato; D Haque; L Liu; William G Kaelin; Ronald C Conaway; Joan Weliky Conaway
The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
Genes & development 1998;12(24):3872-81.
1998: Rodney Moreland; Jay S Hanas; Joan Weliky Conaway; Ronald C Conaway
Mechanism of action of RNA polymerase II elongation factor Elongin. Maximal stimulation of elongation requires conversion of the early elongation complex to an Elongin-activable form.
The Journal of biological chemistry 1998;273(41):26610-7.
1998: KM Lonergan; O Iliopoulos; Michael Ohh; Takumi Kamura; Ronald C Conaway; Joan Weliky Conaway; William G Kaelin
Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.
Molecular and cellular biology 1998;18(2):732-41.
1998: Joan Weliky Conaway; Arik Dvir; Rodney Moreland; Qin Yan; B J Elmendorf; S Tan; Ronald C Conaway
Mechanism of promoter escape by RNA polymerase II.
Cold Spring Harbor symposia on quantitative biology 1998;63():357-64.
1997: Arik Dvir; S Tan; Joan Weliky Conaway; Ronald C Conaway
Promoter escape by RNA polymerase II. Formation of an escape-competent transcriptional intermediate is a prerequisite for exit of polymerase from the promoter.
The Journal of biological chemistry 1997;272(45):28175-8.
1997: Y Takagi; Arnim Pause; Ronald C Conaway; Joan Weliky Conaway
Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein.
The Journal of biological chemistry 1997;272(43):27444-9.
1997: Ali Shilatifard; D Haque; Ronald C Conaway; Joan Weliky Conaway
Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex.
The Journal of biological chemistry 1997;272(35):22355-63.
1997: Arik Dvir; Ronald C Conaway; Joan Weliky Conaway
A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9006-10.
1997: Daniel Reines; Arik Dvir; Joan Weliky Conaway; Ronald C Conaway
Assays for investigating transcription by RNA polymerase II in vitro.
Methods (San Diego, Calif.) 1997;12(3):192-202.
1997: Ali Shilatifard; DR Duan; D Haque; C Florence; W H Schubach; Joan Weliky Conaway; Ronald C Conaway
ELL2, a new member of an ELL family of RNA polymerase II elongation factors.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3639-43.
1997: Ali Shilatifard; Joan Weliky Conaway; Ronald C Conaway
Mechanism and regulation of transcriptional elongation and termination by RNA polymerase II.
Current opinion in genetics & development 1997;7(2):199-204.
1997: Ronald C Conaway; Joan Weliky Conaway
General transcription factors for RNA polymerase II.
Progress in nucleic acid research and molecular biology 1997;56():327-46.
1996: T Aso; D Haque; R J Barstead; Ronald C Conaway; Joan Weliky Conaway
The inducible elongin A elongation activation domain: structure, function and interaction with the elongin BC complex.
The EMBO journal 1996;15(20):5557-66.
1996: Y Takagi; Ronald C Conaway; Joan Weliky Conaway
Characterization of elongin C functional domains required for interaction with elongin B and activation of elongin A.
The Journal of biological chemistry 1996;271(41):25562-8.
1996: Arik Dvir; Ronald C Conaway; Joan Weliky Conaway
Promoter escape by RNA polymerase II. A role for an ATP cofactor in suppression of arrest by polymerase at promoter-proximal sites.
The Journal of biological chemistry 1996;271(38):23352-6.
1996: Daniel Reines; Joan Weliky Conaway; Ronald C Conaway
The RNA polymerase II general elongation factors.
Trends in biochemical sciences 1996;21(9):351-5.
1996: T Aso; Ali Shilatifard; Joan Weliky Conaway; Ronald C Conaway
Transcription syndromes and the role of RNA polymerase II general transcription factors in human disease.
The Journal of clinical investigation 1996;97(7):1561-9.
1996: Arik Dvir; K P Garrett; C Chalut; Jean-Marc Egly; Joan Weliky Conaway; Ronald C Conaway
A role for ATP and TFIIH in activation of the RNA polymerase II preinitiation complex prior to transcription initiation.
The Journal of biological chemistry 1996;271(13):7245-8.
1996: Ali Shilatifard; William Stratton Lane; K W Jackson; Ronald C Conaway; Joan Weliky Conaway
An RNA polymerase II elongation factor encoded by the human ELL gene.
Science (New York, N.Y.) 1996;271(5257):1873-6.
1996: T Aso; D Haque; K Fukudome; C S Brower; Joan Weliky Conaway; Ronald C Conaway
A human cDNA encoding the 110-kDa A subunit of RNA polymerase II transcription factor elongin.
Gene 1996;168(2):277-8.
1996: Arnim Pause; T Aso; W Marston Linehan; Joan Weliky Conaway; Ronald C Conaway; Richard D Klausner
Interaction of von Hippel-Lindau tumor suppressor gene product with elongin.
Methods in enzymology 1996;274():436-41.
1996: Ronald C Conaway; Daniel Reines; K P Garrett; W Powell; Joan Weliky Conaway
Purification of RNA polymerase II general transcription factors from rat liver.
Methods in enzymology 1996;273():194-207.
1995: T Aso; N Mokady; D Haque; Ronald C Conaway; Joan Weliky Conaway
Assignment of a human gene encoding the 110-kDa subunit of general transcription factor elongin (SIII) to chromosome 1p36.1.
Genomics 1995;30(2):393-4.
1995: T Aso; Joan Weliky Conaway; Ronald C Conaway
The RNA polymerase II elongation complex.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(14):1419-28.
1995: Y Takagi; Joan Weliky Conaway; Ronald C Conaway
A novel activity associated with RNA polymerase II elongation factor SIII. SIII directs promoter-independent transcription initiation by RNA polymerase II in the absence of initiation factors.
The Journal of biological chemistry 1995;270(41):24300-5.
1995: T Aso; William Stratton Lane; Joan Weliky Conaway; Ronald C Conaway
Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II.
Science (New York, N.Y.) 1995;269(5229):1439-43.
1995: D R Duan; Arnim Pause; W H Burgess; T Aso; D Y Chen; K P Garrett; Ronald C Conaway; Joan Weliky Conaway; W Marston Linehan; Richard D Klausner
Inhibition of transcription elongation by the VHL tumor suppressor protein.
Science (New York, N.Y.) 1995;269(5229):1402-6.
1995: K P Garrett; T Aso; J N Bradsher; SI Foundling; William Stratton Lane; Ronald C Conaway; Joan Weliky Conaway
Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7172-6.
1995: S Tan; Ronald C Conaway; Joan Weliky Conaway
Dissection of transcription factor TFIIF functional domains required for initiation and elongation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):6042-6.
1994: K P Garrett; D Haque; Ronald C Conaway; Joan Weliky Conaway
A human cDNA encoding the small subunit of RNA polymerase II transcription factor SIII.
Gene 1994;150(2):413-4.
1994: T Aso; Joan Weliky Conaway; Ronald C Conaway
Role of core promoter structure in assembly of the RNA polymerase II preinitiation complex. A common pathway for formation of preinitiation intermediates at many TATA and TATA-less promoters.
The Journal of biological chemistry 1994;269(42):26575-83.
1994: S Tan; T Aso; Ronald C Conaway; Joan Weliky Conaway
Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II.
The Journal of biological chemistry 1994;269(41):25684-91.
1994: S Tan; K P Garrett; Ronald C Conaway; Joan Weliky Conaway
Cryptic DNA-binding domain in the C terminus of RNA polymerase II general transcription factor RAP30.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9808-12.
1994: H Serizawa; Joan Weliky Conaway; Ronald C Conaway
An oligomeric form of the large subunit of transcription factor (TF) IIE activates phosphorylation of the RNA polymerase II carboxyl-terminal domain by TFIIH.
The Journal of biological chemistry 1994;269(32):20750-6.
1994: K P Garrett; S Tan; J N Bradsher; William Stratton Lane; Joan Weliky Conaway; Ronald C Conaway
Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5237-41.
1994: S Tan; Ronald C Conaway; Joan Weliky Conaway
A bacteriophage vector suitable for site-directed mutagenesis and high-level expression of multisubunit proteins in E. coli.
BioTechniques 1994;16(5):824-6, 828.
1994: T Aso; H Serizawa; Ronald C Conaway; Joan Weliky Conaway
A TATA sequence-dependent transcriptional repressor activity associated with mammalian transcription factor IIA.
The EMBO journal 1994;13(2):435-45.
1993: J N Bradsher; K W Jackson; Ronald C Conaway; Joan Weliky Conaway
RNA polymerase II transcription factor SIII. I. Identification, purification, and properties.
The Journal of biological chemistry 1993;268(34):25587-93.
1993: J N Bradsher; S Tan; H J McLaury; Joan Weliky Conaway; Ronald C Conaway
RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation.
The Journal of biological chemistry 1993;268(34):25594-603.
1993: H Serizawa; Ronald C Conaway; Joan Weliky Conaway
Multifunctional RNA polymerase II initiation factor delta from rat liver. Relationship between carboxyl-terminal domain kinase, ATPase, and DNA helicase activities.
The Journal of biological chemistry 1993;268(23):17300-8.
1993: H Serizawa; Joan Weliky Conaway; Ronald C Conaway
Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription.
Nature 1993;363(6427):371-4.
1993: Ronald C Conaway; Joan Weliky Conaway
General initiation factors for RNA polymerase II.
Annual review of biochemistry 1993;62():161-90.
1993: Joan Weliky Conaway; J N Bradsher; S Tan; Ronald C Conaway
Transcription factor SIII: a novel component of the RNA polymerase II elongation complex.
Cellular & molecular biology research 1993;39(4):323-9.
1992: K P Garrett; H Serizawa; J P Hanley; J N Bradsher; A Tsuboi; N Arai; T Yokota; K Arai; Ronald C Conaway; Joan Weliky Conaway
The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function.
The Journal of biological chemistry 1992;267(33):23942-9.
1992: H Serizawa; Ronald C Conaway; Joan Weliky Conaway
A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7476-80.
1992: Joan Weliky Conaway; J N Bradsher; Ronald C Conaway
Mechanism of assembly of the RNA polymerase II preinitiation complex. Transcription factors delta and epsilon promote stable binding of the transcription apparatus to the initiator element.
The Journal of biological chemistry 1992;267(14):10142-8.
1992: Ronald C Conaway; J N Bradsher; Joan Weliky Conaway
Mechanism of assembly of the RNA polymerase II preinitiation complex. Evidence for a functional interaction between the carboxyl-terminal domain of the largest subunit of RNA polymerase II and a high molecular mass form of the TATA factor.
The Journal of biological chemistry 1992;267(12):8464-7.
1991: Joan Weliky Conaway; Ronald C Conaway
Initiation of eukaryotic messenger RNA synthesis.
The Journal of biological chemistry 1991;266(27):17721-4.
1991: Ronald C Conaway; K P Garrett; J P Hanley; Joan Weliky Conaway
Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6205-9.
1991: Joan Weliky Conaway; J P Hanley; K P Garrett; Ronald C Conaway
Transcription initiated by RNA polymerase II and transcription factors from liver. Structure and action of transcription factors epsilon and tau.
The Journal of biological chemistry 1991;266(12):7804-11.
1990: Joan Weliky Conaway; Ronald C Conaway
An RNA polymerase II transcription factor shares functional properties with Escherichia coli sigma 70.
Science (New York, N.Y.) 1990;248(4962):1550-3.
1990: Joan Weliky Conaway; Daniel Reines; Ronald C Conaway
Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation.
The Journal of biological chemistry 1990;265(13):7552-8.
1990: Joan Weliky Conaway; E Travis; Ronald C Conaway
Transcription initiated by RNA polymerase II and purified transcription factors from liver. A complex set of promoter sequences governs formation of the initial complex.
The Journal of biological chemistry 1990;265(13):7564-9.
1990: Ronald C Conaway; Joan Weliky Conaway
Transcription initiated by RNA polymerase II and purified transcription factors from liver. Transcription factors alpha, beta gamma, and delta promote formation of intermediates in assembly of the functional preinitiation complex.
The Journal of biological chemistry 1990;265(13):7559-63.
1989: Ronald C Conaway; Joan Weliky Conaway
An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7356-60.
1989: Joan Weliky Conaway; Ronald C Conaway
A multisubunit transcription factor essential for accurate initiation by RNA polymerase II.
The Journal of biological chemistry 1989;264(4):2357-62.