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Michael Conn

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
68
Janovick, Jo Ann
18
Ulloa-Aguirre, Alfredo
16
Brothers, Shaun
10
Stanislaus, D
9
Cornea, Anda
9
Maya-Núñez, Guadalupe
8
Leaños-Miranda, Alfredo
7
Jennes, Lothar
6
Knollman, Paul
6
Lin, X
5
Kaiser, Ursula
4
Crowley, William
4
Jinnah, Hyder
3
Timossi, Carlos
3
Chin, William

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Publications

TOP 3
Conn P Michael; Janovick Jo Ann
Drug development and the cellular quality control system.
Jardón-Valadez Eduardo; Aguilar-Rojas Arturo; Maya-Núñez Guadalupe; Leaños-Miranda Alfredo; Piñeiro Angel; Conn P Michael; Ulloa-Aguirre Alfredo
Conformational effects of Lys191 in the human GnRH receptor: mutagenesis and molecular dynamics simulations studies.
Lucca-Junior W; Janovick J A; Conn P M
Participation of the endoplasmic reticulum protein chaperone thio-oxidoreductase in gonadotropin-releasing hormone receptor expression at the plasma membrane.

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All Publications

2009: Conn P Michael; Janovick Jo Ann
Drug development and the cellular quality control system.
Trends in pharmacological sciences 2009;30(5):228-33.
2009: Jardón-Valadez Eduardo; Aguilar-Rojas Arturo; Maya-Núñez Guadalupe; Leaños-Miranda Alfredo; Piñeiro Angel; Conn P Michael; Ulloa-Aguirre Alfredo
Conformational effects of Lys191 in the human GnRH receptor: mutagenesis and molecular dynamics simulations studies.
The Journal of endocrinology 2009;201(2):297-307.
2009: Lucca-Junior W; Janovick J A; Conn P M
Participation of the endoplasmic reticulum protein chaperone thio-oxidoreductase in gonadotropin-releasing hormone receptor expression at the plasma membrane.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2009;42(2):164-7.
2009: Janovick Jo Ann; Patny Akshay; Mosley Ralph; Goulet Mark T; Altman Michael D; Rush Thomas S; Cornea Anda; Conn P Michael
Molecular mechanism of action of pharmacoperone rescue of misrouted GPCR mutants: the GnRH receptor.
Molecular endocrinology (Baltimore, Md.) 2009;23(2):157-68.
2009: Conn P Michael; Janovick Jo Ann
Trafficking and quality control of the gonadotropin releasing hormone receptor in health and disease.
Molecular and cellular endocrinology 2009;299(2):137-45.
2009: Janovick Jo Ann; Maya-Núñez Guadalupe; Ulloa-Aguirre Alfredo; Huhtaniemi Ilpo T; Dias James A; Verbost Pieter; Conn P Michael
Increased plasma membrane expression of human follicle-stimulating hormone receptor by a small molecule thienopyr(im)idine.
Molecular and cellular endocrinology 2009;298(1-2):84-8.
2009: Ulloa-Aguirre Alfredo; Conn P Michael
Targeting of G protein-coupled receptors to the plasma membrane in health and disease.
Frontiers in bioscience : a journal and virtual library 2009;14():973-94.
2008: Knollman Paul E; Conn P Michael
Multiple G proteins compete for binding with the human gonadotropin releasing hormone receptor.
Archives of biochemistry and biophysics 2008;477(1):92-7.
2008: Conn P Michael; Parker James V
Physiologists embedded in the animal research war.
The Physiologist 2008;51(3):85, 94-5.
2008: Conn P Michael; Parker James V
The animal research war.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1294-5.
2007: Conn P Michael; Ulloa-Aguirre Alfredo; Ito Joel; Janovick Jo Ann
G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo.
Pharmacological reviews 2007;59(3):225-50.
2007: Janovick Jo Ann; Brothers Shaun P; Cornea Anda; Bush Eugene; Goulet Mark T; Ashton Wallace T; Sauer Daryl R; Haviv Fortuna; Greer Jonathan; Conn P Michael
Refolding of misfolded mutant GPCR: post-translational pharmacoperone action in vitro.
Molecular and cellular endocrinology 2007;272(1-2):77-85.
2007: Samant Manoj P; White Richard; Hong Doley J; Croston Glenn; Conn P Michael; Janovick Jo Ann; Rivier Jean
Structure-activity relationship studies of gonadotropin-releasing hormone antagonists containing S-aryl/alkyl norcysteines and their oxidized derivatives.
Journal of medicinal chemistry 2007;50(9):2067-77.
2007: Janovick Jo Ann; Brothers Shaun P; Knollman Paul E; Conn P Michael
Specializations of a G-protein-coupled receptor that appear to aid with detection of frequency-modulated signals from its ligand.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):384-92.
2006: Brothers Shaun P; Janovick Jo Ann; Conn P Michael
Calnexin regulated gonadotropin-releasing hormone receptor plasma membrane expression.
Journal of molecular endocrinology 2006;37(3):479-88.
2006: Conn P Michael; Knollman Paul E; Brothers Shaun P; Janovick Jo Ann
Protein folding as posttranslational regulation: evolution of a mechanism for controlled plasma membrane expression of a G protein-coupled receptor.
Molecular endocrinology (Baltimore, Md.) 2006;20(12):3035-41.
2006: Ulloa-Aguirre Alfredo; Janovick Jo Ann; Miranda Alfredo Leaños; Conn P Michael
G-protein-coupled receptor trafficking: understanding the chemical basis of health and disease.
ACS chemical biology 2006;1(10):631-8.
2006: Conn P Michael; Janovick Jo Ann; Brothers Shaun P; Knollman Paul E
'Effective inefficiency': cellular control of protein trafficking as a mechanism of post-translational regulation.
The Journal of endocrinology 2006;190(1):13-6.
2006: Leaños-Miranda Alfredo; Ulloa-Aguirre Alfredo; Cervini Laura A; Janovick Jo Ann; Rivier Jean; Conn P Michael
Identification of new gonadotrophin-releasing hormone partial agonists.
The Journal of endocrinology 2006;189(3):509-17.
2006: Janovick Jo Ann; Knollman Paul E; Brothers Shaun P; Ayala-Yáñez Rodrigo; Aziz Abeer S; Conn P Michael
Regulation of G protein-coupled receptor trafficking by inefficient plasma membrane expression: molecular basis of an evolved strategy.
The Journal of biological chemistry 2006;281(13):8417-25.
2005: Knollman Paul E; Janovick Jo Ann; Brothers Shaun P; Conn P Michael
Parallel regulation of membrane trafficking and dominant-negative effects by misrouted gonadotropin-releasing hormone receptor mutants.
The Journal of biological chemistry 2005;280(26):24506-14.
2005: Castro-Fernández Cecilia; Maya-Núñez Guadalupe; Conn P Michael
Beyond the signal sequence: protein routing in health and disease.
Endocrine reviews 2005;26(4):479-503.
2005: Leaños-Miranda Alfredo; Ulloa-Aguirre Alfredo; Janovick Jo Ann; Conn P Michael
In vitro coexpression and pharmacological rescue of mutant gonadotropin-releasing hormone receptors causing hypogonadotropic hypogonadism in humans expressing compound heterozygous alleles.
The Journal of clinical endocrinology and metabolism 2005;90(5):3001-8.
2005: Pask Andrew J; Kanasaki Haruhiko; Kaiser Ursula B; Conn P Michael; Janovick Jo Ann; Stockton David W; Hess David L; Justice Monica J; Behringer Richard R
A novel mouse model of hypogonadotrophic hypogonadism: N-ethyl-N-nitrosourea-induced gonadotropin-releasing hormone receptor gene mutation.
Molecular endocrinology (Baltimore, Md.) 2005;19(4):972-81.
2004: Ulloa-Aguirre Alfredo; Janovick Jo Ann; Brothers Shaun P; Conn P Michael
Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease.
Traffic (Copenhagen, Denmark) 2004;5(11):821-37.
2004: Timossi Carlos; Ortiz-Elizondo Carmen; Pineda David B; Dias James A; Conn P Michael; Ulloa-Aguirre Alfredo
Functional significance of the BBXXB motif reversed present in the cytoplasmic domains of the human follicle-stimulating hormone receptor.
Molecular and cellular endocrinology 2004;223(1-2):17-26.
2004: Meysing Astrid U; Kanasaki Haruhiko; Bedecarrats Gregoy Y; Acierno James S; Conn P Michael; Martin Kathryn A; Seminara Stephanie B; Hall Janet E; Crowley William F; Kaiser Ursula B
GNRHR mutations in a woman with idiopathic hypogonadotropic hypogonadism highlight the differential sensitivity of luteinizing hormone and follicle-stimulating hormone to gonadotropin-releasing hormone.
The Journal of clinical endocrinology and metabolism 2004;89(7):3189-98.
2004: Brothers Shaun P; Cornea Anda; Janovick Jo Ann; Conn P Michael
Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect.
Molecular endocrinology (Baltimore, Md.) 2004;18(7):1787-97.
2004: Ulloa-Aguirre Alfredo; Janovick Jo Ann; Leaños-Miranda Alfredo; Conn P Michael
Misrouted cell surface GnRH receptors as a disease aetiology for congenital isolated hypogonadotrophic hypogonadism.
Human reproduction update 2004;10(2):177-92.
2004: Washington Talitha M; Blum J Joseph; Reed Michael C; Conn P Michael
A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH.
Theoretical biology & medical modelling 2004;1():9.
2003: Janovick Jo Ann; Ulloa-Aguirre Alfredo; Conn P Michael
Evolved regulation of gonadotropin-releasing hormone receptor cell surface expression.
Endocrine 2003;22(3):317-27.
2003: Brothers Shaun P; Janovick Jo Ann; Conn P Michael
Unexpected effects of epitope and chimeric tags on gonadotropin-releasing hormone receptors: implications for understanding the molecular etiology of hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 2003;88(12):6107-12.
2003: Kumar T Rajendra; Agno Julio; Janovick Jo Ann; Conn P Michael; Matzuk Martin M
Regulation of FSHbeta and GnRH receptor gene expression in activin receptor II knockout male mice.
Molecular and cellular endocrinology 2003;212(1-2):19-27.
2003: Leaños-Miranda Alfredo; Ulloa-Aguirre Alfredo; Ji Tae H; Janovick Jo Ann; Conn P Michael
Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans.
The Journal of clinical endocrinology and metabolism 2003;88(7):3360-7.
2003: Janovick Jo Ann; Goulet Mark; Bush Eugene; Greer Jonathan; Wettlaufer David G; Conn P Michael
Structure-activity relations of successful pharmacologic chaperones for rescue of naturally occurring and manufactured mutants of the gonadotropin-releasing hormone receptor.
The Journal of pharmacology and experimental therapeutics 2003;305(2):608-14.
2003: Ulloa-Aguirre Alfredo; Janovick Jo Ann; Leaños-Miranda Alfredo; Conn P Michael
Misrouted cell surface receptors as a novel disease aetiology and potential therapeutic target: the case of hypogonadotropic hypogonadism due to gonadotropin-releasing hormone resistance.
Expert opinion on therapeutic targets 2003;7(2):175-85.
2003: Maya-Núñez Guadalupe; Conn P Michael
Transcriptional regulation of the GnRH receptor gene by glucocorticoids.
Molecular and cellular endocrinology 2003;200(1-2):89-98.
2003: Hirshberg Boaz; Conn P Michael; Uwaifo Gabriel I; Blauer Keith L; Clark Bradly D; Nieman Lynnette K
Ectopic luteinizing hormone secretion and anovulation.
The New England journal of medicine 2003;348(4):312-7.
2002: Leaños-Miranda Alfredo; Janovick Jo Ann; Conn P Michael
Receptor-misrouting: an unexpectedly prevalent and rescuable etiology in gonadotropin-releasing hormone receptor-mediated hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism 2002;87(10):4825-8.
2002: Conn P Michael; Leaños-Miranda Alfredo; Janovick Jo Ann
Protein origami: therapeutic rescue of misfolded gene products.
Molecular interventions 2002;2(5):308-16.
2002: Cornea Anda; Conn P Michael
Measurement of changes in fluorescence resonance energy transfer between gonadotropin-releasing hormone receptors in response to agonists.
Methods (San Diego, Calif.) 2002;27(4):333-9.
2002: Janovick Jo Ann; Maya-Nunez Guadalupe; Conn P Michael
Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: misrouted proteins as a novel disease etiology and therapeutic target.
The Journal of clinical endocrinology and metabolism 2002;87(7):3255-62.
2002: Castro-Fernández Cecilia; Conn P Michael
Regulation of the gonadotropin-releasing hormone receptor (GnRHR) by RGS proteins: role of the GnRHR carboxyl-terminus.
Molecular and cellular endocrinology 2002;191(2):149-56.
2002: Ji Inhae; Lee ChangWoo; Song YongSang; Conn P Michael; Ji Tae H
Cis- and trans-activation of hormone receptors: the LH receptor.
Molecular endocrinology (Baltimore, Md.) 2002;16(6):1299-308.
2002: Maya-Núñez Guadalupe; Janovick Jo Ann; Ulloa-Aguirre Alfredo; Söderlund Daniela; Conn P Michael; Méndez Juan Pablo
Molecular basis of hypogonadotropic hypogonadism: restoration of mutant (E(90)K) GnRH receptor function by a deletion at a distant site.
The Journal of clinical endocrinology and metabolism 2002;87(5):2144-9.
2002: Lee ChangWoo; Ji Inhae; Ryu KiSung; Song YongSang; Conn P Michael; Ji Tae H
Two defective heterozygous luteinizing hormone receptors can rescue hormone action.
The Journal of biological chemistry 2002;277(18):15795-800.
2002: Brothers Shaun P; Janovick Jo Ann; Maya-Nunez Guadalupe; Cornea Anda; Han Xin-Bing; Conn P Michael
Conserved mammalian gonadotropin-releasing hormone receptor carboxyl terminal amino acids regulate ligand binding, effector coupling and internalization.
Molecular and cellular endocrinology 2002;190(1-2):19-27.
2002: Broqua Pierre; Riviere Pierre J-M; Conn P Michael; Rivier Jean E; Aubert Michel L; Junien Jean-Louis
Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: degarelix.
The Journal of pharmacology and experimental therapeutics 2002;301(1):95-102.
2002: Castro-Fernández Cecilia; Janovick Jo Ann; Brothers Shaun P; Fisher Rory A; Ji Tae H; Conn P Michael
Regulation of RGS3 and RGS10 palmitoylation by GnRH.
Endocrinology 2002;143(4):1310-7.
2002: Timossi Carlos; Maldonado David; Vizcaíno Andrea; Lindau-Shepard Barbara; Conn P Michael; Ulloa-Aguirre Alfredo
Structural determinants in the second intracellular loop of the human follicle-stimulating hormone receptor are involved in G(s) protein activation.
Molecular and cellular endocrinology 2002;189(1-2):157-68.
2001: Maya-Núñez G; Conn P M
Cyclic adenosine 3',5'-monophosphate (cAMP) and cAMP responsive element-binding protein are involved in the transcriptional regulation of gonadotropin-releasing hormone (GnRH) receptor by GnRH and mitogen-activated protein kinase signal transduction pathway in GGH(3) cells.
Biology of reproduction 2001;65(2):561-7.
2001: Cornea A; Janovick J A; Maya-Núñez G; Conn P M
Gonadotropin-releasing hormone receptor microaggregation. Rate monitored by fluorescence resonance energy transfer.
The Journal of biological chemistry 2001;276(3):2153-8.
2000: Maya-Núñez G; Janovick J A; Conn P M
Combined modification of intracellular and extracellular loci on human gonadotropin-releasing hormone receptor provides a mechanism for enhanced expression.
Endocrine 2000;13(3):401-7.
2000: Lin X; Janovick J A; Cardenas R; Conn P M; Peter R E
Molecular cloning and expression of a type-two somatostatin receptor in goldfish brain and pituitary.
Molecular and cellular endocrinology 2000;166(2):75-87.
2000: Timossi C M; Barrios-de-Tomasi J; González-Suárez R; Arranz M C; Padmanabhan V; Conn P M; Ulloa-Aguirre A
Differential effects of the charge variants of human follicle-stimulating hormone.
The Journal of endocrinology 2000;165(2):193-205.
2000: Blum J J; Reed M C; Janovick J A; Conn P M
A mathematical model quantifying GnRH-induced LH secretion from gonadotropes.
American journal of physiology. Endocrinology and metabolism 2000;278(2):E263-72.
1999: Pinter J H; Janovick J A; Conn P M
Gonadotropin-releasing hormone receptor concentration differentially regulates intracellular signaling pathways in GGH3 cells.
Pituitary 1999;2(3):181-90.
1999: Ulloa-Aguirre A; Stanislaus D; Janovick J A; Conn P M
Structure-activity relationships of G protein-coupled receptors.
Archives of medical research 1999;30(6):420-35.
1999: Lin X; Janovick J A; Brothers S; Conn P M; Peter R E
Molecular cloning and expression of two type one somatostatin receptors in goldfish brain.
Endocrinology 1999;140(11):5211-9.
1999: Cornea A; Janovick J A; Lin X; Conn P M
Simultaneous and independent visualization of the gonadotropin-releasing hormone receptor and its ligand: evidence for independent processing and recycling in living cells.
Endocrinology 1999;140(9):4272-80.
1999: Maya-Núñez G; Conn P M
Transcriptional regulation of the gonadotropin-releasing hormone receptor gene is mediated in part by a putative repressor element and by the cyclic adenosine 3',5'-monophosphate response element.
Endocrinology 1999;140(8):3452-8.
1999: Han X B; Conn P M
The role of protein kinases A and C pathways in the regulation of mitogen-activated protein kinase activation in response to gonadotropin-releasing hormone receptor activation.
Endocrinology 1999;140(5):2241-51.
1999: Lin X; Conn P M
Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: involvement of multiple signal transduction pathways.
Endocrinology 1999;140(1):358-64.
1998: Lin X; Janovick J A; Conn P M
Mutations at the consensus phosphorylation sites in the third intracellular loop of the rat gonadotropin-releasing hormone receptor: effects on receptor ligand binding and signal transduction.
Biology of reproduction 1998;59(6):1470-6.
1998: Lin X; Cornea A; Janovick J A; Conn P M
Visualization of unoccupied and occupied gonadotropin-releasing hormone receptors in living cells.
Molecular and cellular endocrinology 1998;146(1-2):27-37.
1998: Conn P M; Parker J
Animal rights: reaching the public.
Science (New York, N.Y.) 1998;282(5393):1417.
1998: Stanislaus D; Pinter J H; Janovick J A; Conn P M
Mechanisms mediating multiple physiological responses to gonadotropin-releasing hormone.
Molecular and cellular endocrinology 1998;144(1-2):1-10.
1998: Lin X; Conn P M
Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH and cyclic adenosine monophosphate.
Endocrinology 1998;139(9):3896-902.
1998: Stanislaus D; Ponder S; Ji T H; Conn P M
Gonadotropin-releasing hormone receptor couples to multiple G proteins in rat gonadotrophs and in GGH3 cells: evidence from palmitoylation and overexpression of G proteins.
Biology of reproduction 1998;59(3):579-86.
1998: Stanislaus D; Janovick J A; Ji T; Wilkie T M; Offermanns S; Conn P M
Gonadotropin and gonadal steroid release in response to a gonadotropin-releasing hormone agonist in Gqalpha and G11alpha knockout mice.
Endocrinology 1998;139(6):2710-7.
1998: Ulloa-Aguirre A; Stanislaus D; Arora V; Väänänen J; Brothers S; Janovick J A; Conn P M
The third intracellular loop of the rat gonadotropin-releasing hormone receptor couples the receptor to Gs- and G(q/11)-mediated signal transduction pathways: evidence from loop fragment transfection in GGH3 cells.
Endocrinology 1998;139(5):2472-8.
1998: Lin X; Janovick J A; Brothers S; Blömenrohr M; Bogerd J; Conn P M
Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation.
Molecular endocrinology (Baltimore, Md.) 1998;12(2):161-71.
1998: Cornea A; Janovick J A; Stanislaus D; Conn P M
Redistribution of G(q/11)alpha in the pituitary gonadotrope in response to a gonadotropin-releasing hormone agonist.
Endocrinology 1998;139(1):397-402.
1997: Stanislaus D; Janovick J A; Brothers S; Conn P M
Regulation of G(q/11)alpha by the gonadotropin-releasing hormone receptor.
Molecular endocrinology (Baltimore, Md.) 1997;11(6):738-46.
1997: Kaiser U B; Conn P M; Chin W W
Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines.
Endocrine reviews 1997;18(1):46-70.
1997: Jennes L; Eyigor O; Janovick J A; Conn P M
Brain gonadotropin releasing hormone receptors: localization and regulation.
Recent progress in hormone research 1997;52():475-90; discussion 490-1.
1996: Akita S; Conn P M; Melmed S
Leukemia inhibitory factor (LIF) induces acute adrenocorticotrophic hormone (ACTH) secretion in fetal rhesus macaque primates: a novel dynamic test of pituitary function.
The Journal of clinical endocrinology and metabolism 1996;81(11):4170-8.
1996: Pralong F P; Boepple P A; Conn P M; Whitcomb R W; Butler J P; Schoenfeld D; Crowley W F
Contour of the GnRH pulse independently modulates gonadotropin secretion in the human male.
Neuroendocrinology 1996;64(3):247-56.
1996: Janovick J A; Conn P M
Gonadotropin releasing hormone agonist provokes homologous receptor microaggregation: an early event in seven-transmembrane receptor mediated signaling.
Endocrinology 1996;137(8):3602-5.
1996: Conn P M; Bowers C Y
A new receptor for growth hormone-release peptide.
Science (New York, N.Y.) 1996;273(5277):923.
1996: Janovick J A; Conn P M
Progesterone diminishes the sensitivity of gonadotropin-releasing hormone-stimulated luteinizing hormone (LH) release and protects an LH pool from desensitization: actions opposed by cholera toxin.
Endocrinology 1996;137(5):1823-7.
1996: Stanislaus D; Arora V; Awara W M; Conn P M
Biphasic action of cyclic adenosine 3',5'- monophosphate in gonadotropin-releasing hormone (GnRH) analog-stimulated hormone release from GH3 cells stably transfected with GnRH receptor complementary deoxyribonucleic acid.
Endocrinology 1996;137(3):1025-31.
1996: Awara W M; Guo C H; Conn P M
Effects of Asn318 and Asp87Asn318 mutations on signal transduction by the gonadotropin-releasing hormone receptor and receptor regulation.
Endocrinology 1996;137(2):655-62.
1995: Kaiser U B; Sabbagh E; Katzenellenbogen R A; Conn P M; Chin W W
A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12280-4.
1995: Jennes L; Brame B; Centers A; Janovick J A; Conn P M
Regulation of hippocampal gonadotropin releasing hormone (GnRH) receptor mRNA and GnRH-stimulated inositol phosphate production by gonadal steroid hormones.
Brain research. Molecular brain research 1995;33(1):104-10.
1995: Guo C H; Janovick J A; Kuphal D; Conn P M
Transient transfection of GGH3-1' cells [GH3 cells stably transfected with the gonadotropin-releasing hormone (GnRH) receptor complementary deoxyribonucleic acid] with the carboxyl-terminal of beta-adrenergic receptor kinase 1 blocks prolactin release: evidence for a role of the G protein beta gamma-subunit complex in GnRH signal transduction.
Endocrinology 1995;136(7):3031-6.
1995: Janovick J A; Jennes L; Conn P M
GH3 cells transfected with gonadotropin-releasing hormone (GnRH) receptor complementary deoxyribonucleic acid release secretogranin-II through a constitutive pathway after GnRH analog-regulated synthesis: evidence that secretory proteins do not contain a sequence that obligates processing through a secretory granule or by regulated secretion.
Endocrinology 1995;136(1):202-8.
1995: Conn P M; Janovick J A; Stanislaus D; Kuphal D; Jennes L
Molecular and cellular bases of gonadotropin-releasing hormone action in the pituitary and central nervous system.
Vitamins and hormones 1995;50():151-214.
1994: Stanislaus D; Janovick J A; Jennes L; Kaiser U B; Chin W W; Conn P M
Functional and morphological characterization of four cell lines derived from GH3 cells stably transfected with gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid.
Endocrinology 1994;135(5):2220-7.
1994: Janovick J A; Conn P M
Gonadotropin-releasing hormone (GnRH)-receptor coupling to inositol phosphate and prolactin production in GH3 cells stably transfected with rat GnRH receptor complementary deoxyribonucleic acid.
Endocrinology 1994;135(5):2214-9.
1994: Kaiser U B; Katzenellenbogen R A; Conn P M; Chin W W
Evidence that signalling pathways by which thyrotropin-releasing hormone and gonadotropin-releasing hormone act are both common and distinct.
Molecular endocrinology (Baltimore, Md.) 1994;8(8):1038-48.
1994: Connor J P; Buller R E; Conn P M
Effects of GnRH analogs on six ovarian cancer cell lines in culture.
Gynecologic oncology 1994;54(1):80-6.
1994: Kuphal D; Janovick J A; Kaiser U B; Chin W W; Conn P M
Stable transfection of GH3 cells with rat gonadotropin-releasing hormone receptor complementary deoxyribonucleic acid results in expression of a receptor coupled to cyclic adenosine 3',5'-monophosphate-dependent prolactin release via a G-protein.
Endocrinology 1994;135(1):315-20.
1994: Jennes L; Conn P M
Gonadotropin-releasing hormone and its receptors in rat brain.
Frontiers in neuroendocrinology 1994;15(1):51-77.
1994: Fraser H M; Recio R; Conn P M; Lunn S F
Gonadotropin-releasing hormone antagonist for postpartum contraception: outcome for the mother and male offspring in the marmoset.
The Journal of clinical endocrinology and metabolism 1994;78(1):121-5.
1994: Katayama T; Conn P M
Activin modulates the intracellular signaling system activated by gonadotropin-releasing hormone: dual effect on calcium messenger system and protein kinase-C pathway.
Endocrinology 1994;134(1):119-25.
1994: Conn P M; Crowley W F
Gonadotropin-releasing hormone and its analogs.
Annual review of medicine 1994;45():391-405.
1993: Barnes S J; Conn P M
Cholera toxin and dibutyryl cyclic adenosine 3',5'-monophosphate sensitize gonadotropin-releasing hormone-stimulated inositol phosphate production to inhibition in protein kinase-C (PKC)-depleted cells: evidence for cross-talk between a cholera toxin-sensitive G-protein and PKC.
Endocrinology 1993;133(6):2756-60.
1993: Bagatell C J; Conn P M; Bremner W J
Single-dose administration of the gonadotropin-releasing hormone antagonist, Nal-Lys (antide) to healthy men.
Fertility and sterility 1993;60(4):680-5.
1993: Janovick J A; Haviv F; Fitzpatrick T D; Conn P M
Differential orientation of a GnRH agonist and antagonist in the pituitary GnRH receptor.
Endocrinology 1993;133(2):942-5.
1993: Katayama T; Conn P M
Modulation of activin A action and specificity in the rat gonadotrope by protein kinase C.
Endocrinology 1993;133(2):496-504.
1993: Janovick J A; Conn P M
A cholera toxin-sensitive guanyl nucleotide binding protein mediates the movement of pituitary luteinizing hormone into a releasable pool: loss of this event is associated with the onset of homologous desensitization to gonadotropin-releasing hormone.
Endocrinology 1993;132(5):2131-5.
1993: Hawes B E; Barnes S; Conn P M
Cholera toxin and pertussis toxin provoke differential effects on luteinizing hormone release, inositol phosphate production, and gonadotropin-releasing hormone (GnRH) receptor binding in the gonadotrope: evidence for multiple guanyl nucleotide binding proteins in GnRH action.
Endocrinology 1993;132(5):2124-30.
1993: Hawes B E; Conn P M
Assessment of the role of G proteins and inositol phosphate production in the action of gonadotropin-releasing hormone.
Clinical chemistry 1993;39(2):325-32.
1992: Hawes B E; Conn P M
Development of gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and recovery are not coupled to inositol phosphate production or GnRH receptor number.
Endocrinology 1992;131(6):2681-9.
1992: Hawes B E; Waters S B; Janovick J A; Bleasdale J E; Conn P M
Gonadotropin-releasing hormone-stimulated intracellular Ca2+ fluctuations and luteinizing hormone release can be uncoupled from inositol phosphate production.
Endocrinology 1992;130(6):3475-83.
1992: Conn P M; Janovick J A; Braden T D; Maurer R A; Jennes L
SIIp: a unique secretogranin/chromogranin of the pituitary released in response to gonadotropin-releasing hormone.
Endocrinology 1992;130(5):3033-40.
1992: Cook J S; Doty K L; Conn P M; Hansen J R
Assessment of depot leuprolide acetate dose-adequacy for central precocious puberty.
The Journal of clinical endocrinology and metabolism 1992;74(5):1206-9.
1992: Hawes B E; Marzen J E; Waters S B; Conn P M
Sodium fluoride provokes gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and gonadotrope sensitization to A23187: evidence for multiple G proteins in GnRH action.
Endocrinology 1992;130(5):2465-75.
1992: Waters S B; Conn P M
Maintenance of gonadotropin-releasing hormone (GnRH)-stimulated luteinizing hormone release despite desensitization of GnRH-stimulated cytosolic calcium responses.
Endocrinology 1992;130(4):2091-100.
1992: Conn P M; Hawes B E; Janovick J A
Selection of models for the study of GnRH stimulated gonadotropin release prejudices the assignment of roles for mediators and modulators of hormone action.
Molecular and cellular endocrinology 1992;84(3):C33-7.
1992: Braden T D; Conn P M
Activin-A stimulates the synthesis of gonadotropin-releasing hormone receptors.
Endocrinology 1992;130(4):2101-5.
1991: Pavlou S N; Brewer K; Farley M G; Lindner J; Bastias M C; Rogers B J; Swift L L; Rivier J E; Vale W W; Conn P M
Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido.
The Journal of clinical endocrinology and metabolism 1991;73(6):1360-9.
1991: Gordon K; Williams R F; Danforth D R; Conn P M; Hutchison J S; Hodgen G D
Suppression of ovarian estradiol secretion by a single injection of antide in cynomolgus monkeys during the early follicular phase: immediate, sustained, and reversible actions.
The Journal of clinical endocrinology and metabolism 1991;73(6):1262-8.
1991: Fraser H M; Lunn S F; Cowen G M; Smith K B; Conn P M
Effect of late follicular phase administration of antide on ovulation and inhibin secretion in macaques.
Contraception 1991;44(6):667-76.
1991: Braden T D; Bervig T; Conn P M
Protein kinase-C activation stimulates synthesis of gonadotropin-releasing hormone (GnRH) receptors, but does not mediate GnRH-stimulated receptor synthesis.
Endocrinology 1991;129(5):2486-90.
1991: Janovick J A; Natarajan K; Longo F; Conn P M
Caldesmon: a bifunctional (calmodulin and actin) binding protein which regulates stimulated gonadotropin release.
Endocrinology 1991;129(1):68-74.
1991: Braden T D; Conn P M
The 1990 James A. F. Stevenson Memorial Lecture. Gonadotropin-releasing hormone and its actions.
Canadian journal of physiology and pharmacology 1991;69(4):445-58.
1991: Conn P M; Crowley W F
Gonadotropin-releasing hormone and its analogues.
The New England journal of medicine 1991;324(2):93-103.
1991: Natarajan K; Ness J; Wooge C H; Janovick J A; Conn P M
Specific identification and subcellular localization of three calmodulin-binding proteins in the rat gonadotrope: spectrin, caldesmon, and calcineurin.
Biology of reproduction 1991;44(1):43-52.
1991: Waters S B; Conn P M
Regulation of the pituitary gonadotrope by gonadotropin-releasing hormone: multiple intracellular effectors.
The Chinese journal of physiology 1991;34(1):1-26.
1990: Andrews W V; Hansen J R; Janovick J A; Conn P M
Gonadotropin-releasing hormone modulation of protein kinase-C activity in perifused anterior pituitary cell cultures.
Endocrinology 1990;127(5):2393-9.
1990: Braden T D; Farnworth P G; Burger H G; Conn P M
Regulation of the synthetic rate of gonadotropin-releasing hormone receptors in rat pituitary cell cultures by inhibin.
Endocrinology 1990;127(5):2387-92.
1990: Waters S B; Hawes B E; Conn P M
Stimulation of luteinizing hormone release by sodium fluoride is independent of protein kinase-C activity and unaffected by desensitization to gonadotropin-releasing hormone.
Endocrinology 1990;126(5):2583-91.
1990: Braden T D; Conn P M
Altered rate of synthesis of gonadotropin-releasing hormone receptors: effects of homologous hormone appear independent of extracellular calcium.
Endocrinology 1990;126(5):2577-82.
1990: Misro M M; Conn P M
Atypical flagellar structure associated with endocrine cells of rat pituitary.
Indian journal of experimental biology 1990;28(1):27-31.
1989: Rothfeld J; Hejtmancik J F; Conn P M; Pfaff D W
In situ hybridization for LHRH mRNA following estrogen treatment.
Brain research. Molecular brain research 1989;6(2-3):121-5.
1989: Braden T D; Hawes B E; Conn P M
Synthesis of gonadotropin-releasing hormone receptors by gonadotrope cell cultures: both preexisting receptors and those unmasked by protein kinase-C activators show a similar synthetic rate.
Endocrinology 1989;125(3):1623-9.
1989: Huckle W R; Hawes B E; Conn P M
Protein kinase C-mediated gonadotropin-releasing hormone receptor sequestration is associated with uncoupling of phosphoinositide hydrolysis.
The Journal of biological chemistry 1989;264(15):8619-26.
1989: Conn P M
Does protein kinase C mediate pituitary actions of gonadotropin-releasing hormone?
Molecular endocrinology (Baltimore, Md.) 1989;3(5):755-7.
1989: McArdle C A; Conn P M
Use of protein kinase C-depleted cells for investigation of the role of protein kinase C in stimulus-response coupling in the pituitary.
Methods in enzymology 1989;168():287-301.
1988: Huckle W R; Conn P M
Molecular mechanism of gonadotropin releasing hormone action. II. The effector system.
Endocrine reviews 1988;9(4):387-95.
1988: Hazum E; Conn P M
Molecular mechanism of gonadotropin releasing hormone (GnRH) action. I. The GnRH receptor.
Endocrine reviews 1988;9(4):379-86.
1988: Blumenfeld Z; Frisch L; Conn P M
Gonadotropin-releasing hormone (GnRH) antibodies formation in hypogonadotropic azoospermic men treated with pulsatile GnRH--diagnosis and possible alternative treatment.
Fertility and sterility 1988;50(4):622-9.
1988: Dodson W C; Myers T; Morton P C; Conn P M
Leuprolide acetate: serum and follicular fluid concentrations and effects on human fertilization, embryo growth, and granulosa-lutein cell progesterone accumulation in vitro.
Fertility and sterility 1988;50(4):612-7.
1988: Hall J E; Brodie T D; Badger T M; Rivier J; Vale W; Conn P M; Schoenfeld D; Crowley W F
Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist.
The Journal of clinical endocrinology and metabolism 1988;67(3):524-31.
1988: Gorospe W C; Conn P M
Restoration of the LH secretory response in desensitized gonadotropes.
Molecular and cellular endocrinology 1988;59(1-2):101-10.
1988: Andrews W V; Maurer R A; Conn P M
Stimulation of rat luteinizing hormone-beta messenger RNA levels by gonadotropin releasing hormone. Apparent role for protein kinase C.
The Journal of biological chemistry 1988;263(27):13755-61.
1988: Jennes L; Dalati B; Conn P M
Distribution of gonadrotropin releasing hormone agonist binding sites in the rat central nervous system.
Brain research 1988;452(1-2):156-64.
1988: McArdle C A; Huckle W R; Johnson L A; Conn P M
Enhanced responsiveness of gonadotropes after protein kinase-C activation: postreceptor regulation of gonadotropin releasing hormone action.
Endocrinology 1988;122(5):1905-14.
1988: Wooge C H; Conn P M
Characterization of calmodulin-binding components in the pituitary gonadotrope.
Molecular and cellular endocrinology 1988;56(1-2):41-51.
1988: Valadez F J; Staley D; Conn P M
Release of gonadotropin alpha subunit from rat pituitary cultures in response to GnRH.
Molecular and cellular endocrinology 1988;56(1-2):81-9.
1988: Huckle W R; McArdle C A; Conn P M
Differential sensitivity of agonist- and antagonist-occupied gonadotropin-releasing hormone receptors to protein kinase C activators. A marker for receptor activation.
The Journal of biological chemistry 1988;263(7):3296-302.
1988: Misro M M; Conn P M
Isolation and characterization of gonadotropin-rich secretory granules from rat: depletion by GnRH and by a high affinity agonist.
Molecular and cellular endocrinology 1988;55(2-3):131-40.
1987: Hansen J R; McArdle C A; Conn P M
Relative roles of calcium derived from intra- and extracellular sources in dynamic luteinizing hormone release from perifused pituitary cells.
Molecular endocrinology (Baltimore, Md.) 1987;1(11):808-15.
1987: Gorospe W C; Conn P M
Membrane fluidity regulates development of gonadotrope desensitization to GnRH.
Molecular and cellular endocrinology 1987;53(1-2):131-40.
1987: Handwerger S; Wilson S P; Tyrey L; Conn P M
Biochemical evidence that human placental lactogen and human chorionic gonadotropin are not stored in cytoplasmic secretion granules.
Biology of reproduction 1987;37(1):28-32.
1987: Goldman J M; Cooper R L; Rehnberg G L; Gabel S; McElroy W K; Hein J; Conn P M
Age-related alterations in the stimulated release in vitro of catecholamines and luteinizing hormone-releasing hormone from the male rat hypothalamus.
Neurochemical research 1987;12(7):651-7.
1987: McArdle C A; Gorospe W C; Huckle W R; Conn P M
Homologous down-regulation of gonadotropin-releasing hormone receptors and desensitization of gonadotropes: lack of dependence on protein kinase C.
Molecular endocrinology (Baltimore, Md.) 1987;1(6):420-9.
1987: McArdle C A; Huckle W R; Conn P M
Phorbol esters reduce gonadotrope responsiveness to protein kinase C activators but not to Ca2+-mobilizing secretagogues. Does protein kinase C mediate gonadotropin-releasing hormone action?
The Journal of biological chemistry 1987;262(11):5028-35.
1987: Conn P M; McArdle C A; Andrews W V; Huckle W R
The molecular basis of gonadotropin-releasing hormone (GnRH) action in the pituitary gonadotrope.
Biology of reproduction 1987;36(1):17-35.
1987: Conn P M; Staley D D; Yasumoto T; Huckle W R; Janovick J A
Homologous desensitization with gonadotropin-releasing hormone (GnRH) also diminishes gonadotrope responsiveness to maitotoxin: a role for the GnRH receptor-regulated calcium ion channel in mediation of cellular desensitization.
Molecular endocrinology (Baltimore, Md.) 1987;1(2):154-9.
1987: Gorospe W C; Conn P M
Agents that decrease gonadotropin-releasing hormone (GnRH) receptor internalization do not inhibit GnRH-mediated gonadotrope desensitization.
Endocrinology 1987;120(1):222-9.
1987: Huckle W R; Conn P M
The relationship between gonadotropin-releasing hormone-stimulated luteinizing hormone release and inositol phosphate production: studies with calcium antagonists and protein kinase C activators.
Endocrinology 1987;120(1):160-9.
1987: Rothfeld J M; Hejtmancik J F; Conn P M; Pfaff D W
LHRH messenger RNA in neurons in the intact and castrate male rat forebrain, studied by in situ hybridization.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1987;67(1):113-8.
1987: Wooge C H; Conn P M
Measurement of synergistic effects of protein kinase C activators and calcium ionophore in pituitary cell cultures.
Methods in enzymology 1987;141():429-35.
1987: Huckle W R; Conn P M
Use of lithium ion in measurement of stimulated pituitary inositol phospholipid turnover.
Methods in enzymology 1987;141():149-55.
1987: Andrews W V; Conn P M
Measurement of inositol phospholipid metabolites by one-dimensional thin-layer chromatography.
Methods in enzymology 1987;141():156-68.
1987: Conn P M; Huckle W R; Andrews W V; McArdle C A
The molecular mechanism of action of gonadotropin releasing hormone (GnRH) in the pituitary.
Recent progress in hormone research 1987;43():29-68.
1986: Andrews W V; Staley D D; Huckle W R; Conn P M
Stimulation of luteinizing hormone (LH) release and phospholipid breakdown by guanosine triphosphate in permeabilized pituitary gonadotropes: antagonist action suggests association of a G protein and gonadotropin-releasing hormone receptor.
Endocrinology 1986;119(6):2537-46.
1986: Barrett J; Golander A; Conn P M; Handwerger S
Characterization and partial purification of a serum protein which stimulates the release of human placental lactogen in vitro.
The Journal of clinical endocrinology and metabolism 1986;63(2):336-42.
1986: Conn P M; Hansen J R
Gonadotropin-releasing hormone and its analogs.
Iowa medicine : journal of the Iowa Medical Society 1986;76(8):372-7.
1986: Leiser J; Conn P M; Blum J J
Interpretation of dose-response curves for luteinizing hormone release by gonadotropin-releasing hormone, related peptides, and leukotriene C4 according to a hormone/receptor/effector model.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(16):5963-7.
1986: Ojeda S R; Urbanski H F; Katz K H; Costa M E; Conn P M
Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(13):4932-6.
1986: McArdle C A; Conn P M
Hormone-stimulated redistribution of gonadotrope protein kinase C in vivo: dependence on Ca2+ influx.
Molecular pharmacology 1986;29(6):570-6.
1986: Jinnah H A; Conn P M
Gonadotropin-releasing hormone-mediated desensitization of cultured rat anterior pituitary cells can be uncoupled from luteinizing hormone release.
Endocrinology 1986;118(6):2599-604.
1986: Jennes L; Coy D; Conn P M
Receptor-mediated uptake of GnRH agonist and antagonists by cultured gonadotropes: evidence for differential intracellular routing.
Peptides 1986;7(3):459-63.
1986: Andrews W V; Conn P M
Gonadotropin-releasing hormone stimulates mass changes in phosphoinositides and diacylglycerol accumulation in purified gonadotrope cell cultures.
Endocrinology 1986;118(3):1148-58.
1986: Shivers B D; Harlan R E; Hejtmancik J F; Conn P M; Pfaff D W
Localization of cells containing LHRH-like mRNA in rat forebrain using in situ hybridization.
Endocrinology 1986;118(2):883-5.
1986: Conn P M
The molecular basis of gonadotropin-releasing hormone action.
Endocrine reviews 1986;7(1):3-10.
1986: Conn P M; Ganong B R; Ebeling J; Staley D; Niedel J E; Bell R M
Synthesis and use of diacylglycerols as activators of protein kinase C in neuroendocrine tissue.
Methods in enzymology 1986;124():57-63.
1986: Jennes L; Conn P M; Stumff W E
Synthesis and use of colloidal gold-coupled receptor ligands.
Methods in enzymology 1986;124():36-47.
1986: Conn P M; Staley D; Harris C; Andrews W V; Gorospe W C; McArdle C A; Huckle W R; Hansen J
Mechanism of action of gonadotropin releasing hormone.
Annual review of physiology 1986;48():495-513.
1985: Jinnah H A; Conn P M
GnRH-stimulated LH release from rat anterior pituitary cells in culture: refractoriness and recovery.
The American journal of physiology 1985;249(6 Pt 1):E619-25.
1985: Spratt D I; Crowley W F; Butler J P; Hoffman A R; Conn P M; Badger T M
Pituitary luteinizing hormone responses to intravenous and subcutaneous administration of gonadotropin-releasing hormone in men.
The Journal of clinical endocrinology and metabolism 1985;61(5):890-5.
1985: Conn P M; Staley D; Jinnah H; Bates M
Molecular mechanism of gonadotropin releasing hormone action.
Journal of steroid biochemistry 1985;23(5B):703-10.
1985: Kasson B G; Conn P M; Hsueh A J
Inhibition of granulosa cell differentiation by dioctanoylglycerol--a novel activator of protein kinase C.
Molecular and cellular endocrinology 1985;42(1):29-37.
1985: Harris C E; Staley D; Conn P M
Diacylglycerols and protein kinase C. Potential amplifying mechanism for Ca2+-mediated gonadotropin-releasing hormone-stimulated luteinizing hormone release.
Molecular pharmacology 1985;27(5):532-6.
1985: Conn P M; Venter J C
Radiation inactivation (target size analysis) of the gonadotropin-releasing hormone receptor: evidence for a high molecular weight complex.
Endocrinology 1985;116(4):1324-6.
1985: Clapper D L; Conn P M
Gonadotropin-releasing hormone stimulation of pituitary gonadotrope cells produces an increase in intracellular calcium.
Biology of reproduction 1985;32(2):269-78.
1985: Conn P M; Ganong B R; Ebeling J; Staley D; Neidel J E; Bell R M
Diacylglycerols release LH: structure-activity relations reveal a role for protein kinase C.
Biochemical and biophysical research communications 1985;126(1):532-9.
1985: Conn P M; Rogers D C; Seay S G; Jinnah H; Bates M; Luscher D
Regulation of gonadotropin release, GnRH receptors, and gonadotrope responsiveness: a role for GnRH receptor microaggregation.
Journal of cellular biochemistry 1985;27(1):13-21.
1985: Jennes L; Bronson D; Stumpf W E; Conn P M
Evidence for an association between calmodulin and membrane patches containing gonadotropin-releasing hormone--receptor complexes in cultured gonadotropes.
Cell and tissue research 1985;239(2):311-5.
1984: Conn P M; Rogers D C; Seay S G; Staley D
Activation of luteinizing hormone release from pituitary cells by polycations.
Endocrinology 1984;115(5):1913-7.
1984: Bates M D; Conn P M
Calcium mobilization in the pituitary gonadotrope: relative roles of intra- and extracellular sources.
Endocrinology 1984;115(4):1380-5.
1984: Handwerger S; Wilson S; Conn P M
Different subcellular storage sites for decidual- and pituitary-derived prolactin: possible explanation for differences in regulation.
Molecular and cellular endocrinology 1984;37(1):83-7.
1984: Conn P M; Hsueh A J; Crowley W F
Gonadotropin-releasing hormone: molecular and cell biology, physiology, and clinical applications.
Federation proceedings 1984;43(9):2351-61.
1984: Cooper R L; Roberts B; Rogers D C; Seay S G; Conn P M
Endocrine status versus chronologic age as predictors of altered luteinizing hormone secretion in the "aging" rat.
Endocrinology 1984;114(2):391-6.
1984: Conn P M; Rogers D C; Seay S G
Biphasic regulation of the gonadotropin-releasing hormone receptor by receptor microaggregation and intracellular Ca2+ levels.
Molecular pharmacology 1984;25(1):51-5.
1984: Jennes L; Stumpf W E; Conn P M
Receptor-mediated binding and uptake of GnRH agonist and antagonist by pituitary cells.
Peptides 1984;5 Suppl 1():215-20.
1983: Conn P M; Rogers D C; Seay S G
Structure-function relationship of calcium ion channel antagonists at the pituitary gonadotrope.
Endocrinology 1983;113(5):1592-5.
1983: Jennes L; Stumpf W E; Conn P M
Intracellular pathways of electron-opaque gonadotropin-releasing hormone derivatives bound by cultured gonadotropes.
Endocrinology 1983;113(5):1683-9.
1983: Phillips J H; Burridge K; Conn P M
Cytoskeletal proteins in cultured secretory cells from rat pituitary.
Experimental cell research 1983;148(1):235-42.
1983: Handwerger S; Barry S; Markoff E; Barrett J; Conn P M
Stimulation of the synthesis and release of decidual prolactin by a placental polypeptide.
Endocrinology 1983;112(4):1370-4.
1983: Smith W A; Conn P M
GnRH-mediated desensitization of the pituitary gonadotrope is not calcium dependent.
Endocrinology 1983;112(1):408-10.
1983: Marian J; Conn P M
Subcellular localization of the receptor for gonadotropin-releasing hormone in pituitary and ovarian tissue.
Endocrinology 1983;112(1):104-12.
1983: Hart R C; Bates M D; Cormier M J; Rosen G M; Conn P M
Synthesis and characterization of calmodulin antagonistic drugs.
Methods in enzymology 1983;102():195-204.
1983: Conn P M
Ligand dimerization: a technique for assessing receptor-receptor interactions.
Methods in enzymology 1983;103():49-58.
1983: Conn P M
Use of specific ion channel activating and inhibiting drugs in neuroendocrine tissue.
Methods in enzymology 1983;103():401-5.
1982: Smith W A; Cooper R L; Conn P M
Altered pituitary responsiveness to gonadotropin- releasing hormone in middle-aged rats with 4-day estrous cycles.
Endocrinology 1982;111(6):1843-8.
1982: Blum J J; Conn P M
Gonadotropin-releasing hormone stimulation of luteinizing hormone release: A ligand-receptor-effector model.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(23):7307-11.
1982: Conn P M; Rogers D C; McNeil R
Potency enhancement of a GnRH agonist: GnRH-receptor microaggregation stimulates gonadotropin release.
Endocrinology 1982;111(1):335-7.
1982: Smith D E; Conn P M
The site of estradiol sensitization of the gonadotrope is prior to calcium mobilization.
Life sciences 1982;30(17):1495-8.
1982: Conn P M; Rogers D C; Stewart J M; Niedel J; Sheffield T
Conversion of a gonadotropin-releasing hormone antagonist to an agonist.
Nature 1982;296(5858):653-5.
1981: Conn P M; Hazum E
Luteinizing hormone release and gonadotropin-releasing hormone (GnRH) receptor internalization: independent actions of GnRH.
Endocrinology 1981;109(6):2040-5.
1981: Conn P M; Rogers D C; Sheffield T
Inhibition of gonadotropin-releasing hormone-stimulated luteinizing hormone release by pimozide: evidence for a site of action after calcium mobilization.
Endocrinology 1981;109(4):1122-6.
1981: Conn P M; Chafouleas J G; Rogers D; Means A R
Gonadotropin releasing hormone stimulates calmodulin redistribution in rat pituitary.
Nature 1981;292(5820):264-5.
1981: Handwerger S; Conn P M; Barrett J; Barry S; Golander A
Human placental lactogen release in vitro: paradoxical effects of calcium.
The American journal of physiology 1981;240(5):E550-5.
1981: Marian J; Cooper R L; Conn P M
Regulation of the rat pituitary gonadotropin-releasing hormone receptor.
Molecular pharmacology 1981;19(3):399-405.
1981: Stern J E; Conn P M
Perifusion of rat pituitaries: requirements for optimal GnRH-stimulated LH release.
The American journal of physiology 1981;240(5):E504-9.
1981: Conn P M; Smith R G; Rogers D C
Stimulation of pituitary gonadotropin release does not require internalization of gonadotropin-releasing hormone.
The Journal of biological chemistry 1981;256(3):1098-100.
1981: Conn P M; Marian J; McMillian M; Stern J; Rogers D; Hamby M; Penna A; Grant E
Gonadotropin-releasing hormone action in the pituitary: a three step mechanism.
Endocrine reviews 1981;2(2):174-85.
1980: Jones P B; Conn P M; Marian J; Hsueh A J
Binding of gonadotropin releasing hormone agonist to rat ovarian granulosa cells.
Life sciences 1980;27(22):2125-32.
1980: Conn P M; Rogers D C
Gonadotropin release from pituitary cultures following activation of endogenous ion channels.
Endocrinology 1980;107(6):2133-4.
1980: Hazum E; Cuatrecasas P; Marian J; Conn P M
Receptor-mediated internalization of fluorescent gonadotropin-releasing hormone by pituitary gonadotropes.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6692-5.
1980: Cooper R L; Conn P M; Walker R F
Characterization of the LH surge in middle-aged female rats.
Biology of reproduction 1980;23(3):611-5.
1980: Marian J; Conn P M
The calcium requirement in GnRH-stimulated LH release is not mediated through a specific action on receptor binding.
Life sciences 1980;27(1):87-92.
1980: Conn P M; Whorton R; Lazar J
An inhibitor of arachidonic acid metabolism stimulates luteinizing hormone (LH) release from cultured pituitary cells.
Prostaglandins 1980;19(6):873-9.
1980: Conn P M; Cooper R; McNamara C; Rogers D C; Shoenhardt L
Qualitative change in gonadotropin during normal aging in the male rat.
Endocrinology 1980;106(5):1549-53.
1979: Conn P M; Rogers D C; Sandhu F S
Alteration of the intracellular calcium level stimulates gonadotropin release from cultured rat anterior pituitary cells.
Endocrinology 1979;105(5):1122-7.
1979: Marian J; Conn P M
Gonadotropin releasing hormone stimulation of cultured pituitary cells requires calcium.
Molecular pharmacology 1979;16(1):196-201.
1979: Conn P M; Rogers D C
Restoration of responsiveness to gonadotropin releasing hormone (GnRH) in calcium-depleted rat pituitary cells.
Life sciences 1979;24(26):2461-5.
1979: Conn P M; Morrell D V; Dufau M L; Catt K J
Gonadotropin-releasing hormone action in cultured pituicytes: independence of luteinizing hormone release and adenosine 3',5'-monophosphate production.
Endocrinology 1979;104(2):448-53.
1979: Catt K J; Harwood J P; Richert N D; Conn P M; Conti M; Dufau M L
Luteal desensitization: hormonal regulation of LH receptors, adenylate cyclase and steroidogenic responses in the luteal cell.
Advances in experimental medicine and biology 1979;112():647-62.
1978: Conn P M; Conti M; Harwood J P; Dufau M L; Catt K J
Internalisation of gonadotrophin--receptor complex in ovarian luteal cells.
Nature 1978;274(5671):598-600.
1978: Harwood J P; Conti M; Conn P M; Dufau M L; Catt K J
Receptor regulation and target cell responses: studies in the ovarian luteal cell.
Molecular and cellular endocrinology 1978;11(2):121-35.
1978: Lewis M; Bourke J R; Conn P; Evered D C
Is thyroxine solely a prohormone in the rat? [proceedings]
The Journal of endocrinology 1978;77(2):32P-33P.
1978: Dufau M L; Horner K A; Hayashi K; Tsuruhara T; Conn P M; Catt K J
Actions of choleragen and gonadotropin in isolated Leydig cells. Functional compartmentalization of the hormone-activated cyclic AMP response.
The Journal of biological chemistry 1978;253(10):3721-9.
1977: Mace M L; Van N T; Conn P M
Electron microscopic localization of DNA-dependent RNA polymerase binding sites on DNA using enzyme immobilized on colloidal gold.
Cell biology international reports 1977;1(6):527-33.
1977: Conn P M; Tsuruhara T; Dufau M; Catt K J
Isolation of highly purified Leydig cells by density gradient centrifugation.
Endocrinology 1977;101(2):639-42.
1977: Wray W; Conn P M; Wray V P
Isolation of nuclei using hexylene glycol.
Methods in cell biology 1977;16():69-86.
1975: Conn P M; O'Malley B
Lysozyme (muramidase) in isolated chick oviduct nuclei.
Biochemical and biophysical research communications 1975;64(2):740-6.

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