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Karel Allegaert

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TOP 3
Allegaert Karel
Aminoglycoside pharmacokinetics in neonates: the need to search for covariates of variability in addition to case descriptions.
Cannie Mieke M; Jani Jacques C; De Keyzer Frederik; Allegaert Karel; Dymarkowski Steven; Deprest Jan
Evidence and patterns in lung response after fetal tracheal occlusion: clinical controlled study.
Allegaert Karel; Vanhaesebrouck Sophie; Verbesselt Rene; van den Anker John N
In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age.

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2009: Allegaert Karel
Aminoglycoside pharmacokinetics in neonates: the need to search for covariates of variability in addition to case descriptions.
Acta paediatrica (Oslo, Norway : 1992) 2009;98(10):1546; author reply 1546-7.
2009: Cannie Mieke M; Jani Jacques C; De Keyzer Frederik; Allegaert Karel; Dymarkowski Steven; Deprest Jan
Evidence and patterns in lung response after fetal tracheal occlusion: clinical controlled study.
Radiology 2009;252(2):526-33.
2009: Allegaert Karel; Vanhaesebrouck Sophie; Verbesselt Rene; van den Anker John N
In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age.
Therapeutic drug monitoring 2009;31(4):411-5.
2009: Vanhaesebrouck Sophie; Cossey Veerle; Cosaert Katrien; Allegaert Karel; Naulaers Gunnar
Cardiorespiratory depression and hyperglycemia after unintentional ingestion of brimonidine in a neonate.
European journal of ophthalmology 2009;19(4):694-5.
2009: Allegaert Karel; Veyckemans Francis; Tibboel Dick
Clinical practice: analgesia in neonates.
European journal of pediatrics 2009;168(7):765-70.
2009: Deprest Jan A; Gratacos Eduardo; Nicolaides Kypros; Done Elise; Van Mieghem Tim; Gucciardo Leonardo; Claus Filip; Debeer Anne; Allegaert Karel; Reiss Irwin; Tibboel Dick
Changing perspectives on the perinatal management of isolated congenital diaphragmatic hernia in Europe.
Clinics in perinatology 2009;36(2):329-47, ix.
2009: Allegaert Karel; Ilett Kenneth F; Koren Gideon
Tramadol withdrawal in a neonate: only one of the clinical presentations to be anticipated...
European journal of clinical pharmacology 2009;65(6):643-4; author reply 645.
2009: Allegaert Karel
Is propofol the perfect hypnotic agent for procedural sedation in neonates?
Current clinical pharmacology 2009;4(2):84-6.
2009: Anderson Brian J; Allegaert Karel
Intravenous neonatal paracetamol dosing: the magic of 10 days.
Paediatric anaesthesia 2009;19(4):289-95.
2009: Allegaert Karel; van Mieghem Tim; Verbesselt Rene; de Hoon Jan; Rayyan Maissa; Devlieger Roland; Deprest Jan; Anderson Brian J
Cefazolin pharmacokinetics in maternal plasma and amniotic fluid during pregnancy.
American journal of obstetrics and gynecology 2009;200(2):170.e1-7.
2009: Allegaert Karel; Van Mieghem Tim; Verbesselt Rene; Vanhole Christine; Devlieger Roland; Cossey Veerle; Deprest Jan; de Hoon Jan
Cefazolin plasma protein binding saturability during pregnancy.
Methods and findings in experimental and clinical pharmacology 2009;31(1):25-8.
2008: Allegaert Karel; Scheers Isabelle; Cossey Veerle; Anderson Brian J
Covariates of amikacin clearance in neonates: the impact of postnatal age on predictability.
Drug metabolism letters 2008;2(4):286-9.
2008: Cannie M; Jani J; Meersschaert J; Allegaert K; Done' E; Marchal G; Deprest J; Dymarkowski S
Prenatal prediction of survival in isolated diaphragmatic hernia using observed to expected total fetal lung volume determined by magnetic resonance imaging based on either gestational age or fetal body volume.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;32(5):633-9.
2008: Allegaert K; Scheers I; Adams E; Brajanoski G; Cossey V; Anderson B J
Cerebrospinal fluid compartmental pharmacokinetics of amikacin in neonates.
Antimicrobial agents and chemotherapy 2008;52(6):1934-9.
2008: Allegaert Karel; van Schaik Ron H N; Vermeersch Steve; Verbesselt Rene; Cossey Veerle; Vanhole Christine; van Fessem Marianne; de Hoon Jan; van den Anker John N
Postmenstrual age and CYP2D6 polymorphisms determine tramadol o-demethylation in critically ill neonates and infants.
Pediatric research 2008;63(6):674-9.
2008: Brajanoski Gordana; Hoogmartens Jos; Allegaert Karel; Adams Erwin
Determination of amikacin in cerebrospinal fluid by high-performance liquid chromatography with pulsed electrochemical detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;867(1):149-52.
2008: Allegaert Karel; Rayyan Maissa; De Rijdt Thomas; Van Beek Frank; Naulaers Gunnar
Hepatic tolerance of repeated intravenous paracetamol administration in neonates.
Paediatric anaesthesia 2008;18(5):388-92.
2008: Allegaert K; Vanhole C; Vermeersch S; Rayyan M; Verbesselt R; de Hoon J
Both postnatal and postmenstrual age contribute to the interindividual variability in tramadol glucuronidation in neonates.
Early human development 2008;84(5):325-30.
2008: Allegaert K; van den Anker J N; de Hoon J N; van Schaik R H N; Debeer A; Tibboel D; Naulaers G; Anderson B J
Covariates of tramadol disposition in the first months of life.
British journal of anaesthesia 2008;100(4):525-32.
2008: Staelens Sofie; Van den Driessche Mieke; Barclay Denis; Carrié-Faessler Anne-Lise; Haschke Ferdinand; Verbeke Kristin; Vandebroek Hilde; Allegaert Karel; Van Overmeire Bart; Van Damme Mieke; Veereman-Wauters Gigi
Gastric emptying in healthy newborns fed an intact protein formula, a partially and an extensively hydrolysed formula.
Clinical nutrition (Edinburgh, Scotland) 2008;27(2):264-8.
2008: Vanhaesebrouck S; Vanhole C; de Zegher F; Allegaert K
Influence of duration of parenteral nutrition on retinopathy of prematurity.
Archives of disease in childhood. Fetal and neonatal edition 2008;93(2):F170.
2008: Allegaert K; Verbesselt R; Naulaers G; van den Anker J N; Rayyan M; Debeer A; de Hoon J
Developmental pharmacology: neonates are not just small adults...
Acta clinica Belgica 2008;63(1):16-24.
2008: Allegaert K; de Hoon J; Naulaers G; Van De Velde M
Neonatal clinical pharmacology: recent observations of relevance for anaesthesiologists.
Acta anaesthesiologica Belgica 2008;59(4):283-8.
2007: Allegaert K; Peeters M Y; Verbesselt R; Tibboel D; Naulaers G; de Hoon J N; Knibbe C A
Inter-individual variability in propofol pharmacokinetics in preterm and term neonates.
British journal of anaesthesia 2007;99(6):864-70.
2007: Allegaert Karel; de Hoon Jan; Verbesselt Rene; Naulaers Gunnar; Murat Isabelle
Maturational pharmacokinetics of single intravenous bolus of propofol.
Paediatric anaesthesia 2007;17(11):1028-34.
2007: Allegaert Karel; Murat Isabelle; Anderson Brian J
Not all intravenous paracetamol formulations are created equal...
Paediatric anaesthesia 2007;17(8):811-2.
2007: Allegaert Karel; Van de Velde Marc
Blunted inflammatory and faster clinical recovery following laser treatment compared to cryotherapy.
Archives of disease in childhood 2007;92(7):655.
2007: Allegaert Karel; Anderson Brian J; van den Anker John N; Vanhaesebrouck Sophie; de Zegher Francis
Renal drug clearance in preterm neonates: relation to prenatal growth.
Therapeutic drug monitoring 2007;29(3):284-91.
2007: Allegaert K; Verbesselt R; Rayyan M; Debeer A; de Hoon J
Urinary metabolites to assess in vivo ontogeny of hepatic drug metabolism in early neonatal life.
Methods and findings in experimental and clinical pharmacology 2007;29(4):251-6.
2007: Allegaert K; van de Velde M; Casteels I
Variation in management during and after retinal surgery for retinopathy of prematurity.
Eye (London, England) 2007;21(5):679-80.
2007: Naulaers G; Daniels H; Allegaert K; Rayyan M; Debeer A; Devlieger H
Cardiorespiratory events recorded on home monitors: the effect of prematurity on later serious events.
Acta paediatrica (Oslo, Norway : 1992) 2007;96(2):195-8.
2007: Allegaert Karel; van den Anker John N; Naulaers Gunnar; de Hoon Jan
Determinants of drug metabolism in early neonatal life.
Current clinical pharmacology 2007;2(1):23-9.
2007: Allegaert Karel; Simons Sinno H; Vanhole Christine; Tibboel Dick
Developmental pharmacokinetics of opioids in neonates.
Journal of opioid management 2007;3(1):59-64.
2007: Anderson Brian J; Allegaert Karel; Van den Anker John N; Cossey Veerle; Holford Nicholas H G
Vancomycin pharmacokinetics in preterm neonates and the prediction of adult clearance.
British journal of clinical pharmacology 2007;63(1):75-84.
2007: Rayyan Maissa; Allegaert Karel
Pharmacotherapy during neonatal extracorporeal membrane oxygenation: toward an evidence-based approach.
Critical care (London, England) 2007;11(1):107.
2006: Allegaert Karel; Anderson Brian J
Interindividual variability of aminoglycoside pharmacokinetics in preterm neonates at birth.
European journal of clinical pharmacology 2006;62(12):1011-2.
2006: Anderson Brian J; Allegaert Karel; Holford Nicholas H G
Population clinical pharmacology of children: modelling covariate effects.
European journal of pediatrics 2006;165(12):819-29.
2006: Anderson Brian J; Allegaert Karel; Holford Nicholas H G
Population clinical pharmacology of children: general principles.
European journal of pediatrics 2006;165(11):741-6.
2006: Allegaert K; Rayyan M; Anderson B J
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Methods and findings in experimental and clinical pharmacology 2006;28(8):519-22.
2006: Allegaert K; Debeer A
Circulatory effects of antenatal betamethasone therapy in low birthweight infants.
Archives of disease in childhood. Fetal and neonatal edition 2006;91(5):F389-90.
2006: Allegaert K; Van den Anker J N; Debeer A; Cossey V; Verbesselt R; Tibboel D; Devlieger H; de Hoon J
Maturational changes in the in vivo activity of CYP3A4 in the first months of life.
International journal of clinical pharmacology and therapeutics 2006;44(7):303-8.
2006: Allegaert Karel; Lewi Liesbeth; Naulaers Gunnar; Lagae Lieven
Levetiracetam pharmacokinetics in neonates at birth.
Epilepsia 2006;47(6):1068-9.
2006: Allegaert Karel; Debeer Anne; Cossey Veerle; Rayyan Maissa; Devlieger Hugo
Dopamine is not an independent risk factor for reduced amikacin clearance in extremely low-birth-weight infants.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2006;7(2):143-6.
2006: Allegaert Karel; Rayyan M; de Hoon J; Tibboel D; Verbesselt R; Naulaers G; Van den Anker J N; Devlieger H
Contribution of glucuronidation to tramadol disposition in early neonatal life.
Basic & clinical pharmacology & toxicology 2006;98(1):110-2.
2006: Allegaert Karel; Anderson Brian J; Cossey Veerle; Holford Nicholas H G
Limited predictability of amikacin clearance in extreme premature neonates at birth.
British journal of clinical pharmacology 2006;61(1):39-48.
2006: Allegaert K; Van de Velde M; Debeer A; Casteels I; Devlieger H
Cryotherapy versus laser photocoagulation for threshold retinopathy of prematurity: impact on early postoperative clinical recovery.
Bulletin de la Société belge d'ophtalmologie 2006;(300):7-10.
2005: Allegaert Karel; Van den Anker J N; Verbesselt R; de Hoon J; Vanhole C; Tibboel D; Devlieger H
O-demethylation of tramadol in the first months of life.
European journal of clinical pharmacology 2005;61(11):837-42.
2005: Allegaert Karel; Vanhole Christine; de Hoon Jan; Guignard Jean Pierre; Tibboel Dick; Devlieger Hugo; Van Overmeire Bart
Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates.
Pediatric nephrology (Berlin, Germany) 2005;20(11):1557-61.
2005: Allegaert Karel; de Hoon Jan; Verbesselt Rene; Vanhole Christine; Devlieger Hugo; Tibboel Dick
Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates.
Acta paediatrica (Oslo, Norway : 1992) 2005;94(9):1273-9.
2005: Allegaert K; Devlieger H; Casteels I
Reduced inflammatory response after laser photocoagulation compared with cryoablation for threshold retinopathy of prematurity.
Journal of pediatric ophthalmology and strabismus 2005;42(5):264-6.
2005: Allegaert K; Anderson B J; Verbesselt R; Debeer A; de Hoon J; Devlieger H; Van Den Anker J N; Tibboel D
Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.
British journal of anaesthesia 2005;95(2):231-9.
2005: Allegaert Karel; Daniels Hans; Naulaers Gunnar; Tibboel Dick; Devlieger Hugo
Pharmacodynamics of chloral hydrate in former preterm infants.
European journal of pediatrics 2005;164(7):403-7.
2005: Allegaert Karel; Cossey Veerle; Debeer Anne; Langhendries Jean Paul; Van Overmeire Bart; de Hoon Jan; Devlieger Hugo
The impact of ibuprofen on renal clearance in preterm infants is independent of the gestational age.
Pediatric nephrology (Berlin, Germany) 2005;20(6):740-3.
2005: Anderson Brian J; Pons Gerard; Autret-Leca Elisabeth; Allegaert Karel; Boccard Eric
Pediatric intravenous paracetamol (propacetamol) pharmacokinetics: a population analysis.
Paediatric anaesthesia 2005;15(4):282-92.
2005: Allegaert K; de Hoon J; Verbesselt R; Devlieger H; Tibboel D
Tramadol concentrations in blood and in cerebrospinal fluid in a neonate.
European journal of clinical pharmacology 2005;60(12):911-3.
2005: Naulaers G; Delanghe G; Allegaert K; Debeer A; Cossey V; Vanhole C; Casaer P; Devlieger H; Van Overmeire B
Ibuprofen and cerebral oxygenation and circulation.
Archives of disease in childhood. Fetal and neonatal edition 2005;90(1):F75-6.
2005: Allegaert K; de Hoon J; Van Overmeire B; Devlieger H
Clinical pharmacology of non opioid analgesics in neonates.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2005;67(5-6):289-315.
2005: Allegaert Karel; Devlieger Hugo; Bulckaert Dominiek; Naulaers Gunnar; Casaer Paul; Tibboel Dick
Variability in pain expression characteristics in former preterm infants.
Journal of perinatal medicine 2005;33(5):442-8.
2004: Allegaert Karel; Vanhole Christine; Van Helvoirt Maria; Vanhaesebrouck Sophie; Gewillig Marc; Debeer Anne; Devlieger Hugo; de Zegher Francis
Association of patent ductus arteriosus and severe hypothyroidism in term newborns: coincidence or causal?
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(6):339-41.
2004: Van Overmeire Bart; Allegaert Karel; Casaer Alexandra; Debauche Christian; Decaluwé Wim; Jespers Ann; Weyler Joost; Harrewijn Inge; Langhendries Jean-Paul
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.
Lancet 2004;364(9449):1945-9.
2004: Vanhaesebrouck Piet; Allegaert Karel; Bottu Jean; Debauche Christian; Devlieger Hugo; Docx Martine; François Anne; Haumont Dominique; Lombet Jacques; Rigo Jacques; Smets Koenraad; Vanherreweghe Inge; Van Overmeire Bart; Van Reempts Patrick;
The EPIBEL study: outcomes to discharge from hospital for extremely preterm infants in Belgium.
Pediatrics 2004;114(3):663-75.
2004: Vanhole C; Jannes F; Vrancken M; Naulaers G; Allegaert K; Willems L; Devlieger H
Continuous infusion of medications in very low birth weight infants.
European journal of clinical pharmacology 2004;60(5):383-6.
2004: Rayyan M; Naulaers G; Daniels H; Allegaert K; Debeer A; Devlieger H
Characteristics of respiratory syncytial virus-related apnoea in three infants.
Acta paediatrica (Oslo, Norway : 1992) 2004;93(6):847-9.
2004: Allegaert Karel; Anderson Brian J; Naulaers Gunnar; de Hoon Jan; Verbesselt Rene; Debeer Anne; Devlieger Hugo; Tibboel Dick
Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates.
European journal of clinical pharmacology 2004;60(3):191-7.
2004: Allegaert K; Naulaers G; Debeer A; Breysem L; Ferens I; Vanhole C; Devlieger H; Tibboel D
The use of methohexital during chest tube removal in neonates.
Paediatric anaesthesia 2004;14(4):308-12.
2004: Tesselaar Coranne D; Postema Roelf R; van Dooren Marieke F; Allegaert Karel; Tibboel Dick
Congenital diaphragmatic hernia and situs inversus totalis.
Pediatrics 2004;113(3 Pt 1):e256-8.
2004: Allegaert K; Verbesselt R; Devlieger H; de Hoon J; Tibboel D
Cerebrospinal fluid pharmacokinetics of paracetamol after intravenous propacetamol in a former preterm infant.
British journal of clinical pharmacology 2004;57(2):224-5.
2004: Allegaert K; Cossey V; Naulaers G; Vanhole C; Devlieger H; Casteels I
Dopamine is an indicator but not an independent risk factor for grade 3 retinopathy of prematurity in extreme low birthweight infants.
The British journal of ophthalmology 2004;88(2):309-10.
2004: Allegaert K; Van der Marel C D; Debeer A; Pluim M A L; Van Lingen R A; Vanhole C; Tibboel D; Devlieger H
Pharmacokinetics of single dose intravenous propacetamol in neonates: effect of gestational age.
Archives of disease in childhood. Fetal and neonatal edition 2004;89(1):F25-8.
2004: Allegaert K; Miserez M; Lerut T; Naulaers G; Vanhole C; Devlieger H
Methemoglobinemia and hemolysis after enteral administration of methylene blue in a preterm infant: relevance for pediatric surgeons.
Journal of pediatric surgery 2004;39(1):E35-7.
2004: Allegaert K; Cossey V; Langhendries J P; Naulaers G; Vanhole C; Devlieger H; Van Overmeire B
Effects of co-administration of ibuprofen-lysine on the pharmacokinetics of amikacin in preterm infants during the first days of life.
Biology of the neonate 2004;86(3):207-11.
2003: Allegaert K; Casteels I; Cossey V; Devlieger H
Retinopathy of prematurity: any difference in risk factors between a high and low risk population?
European journal of ophthalmology 2003;13(9-10):784-8.
2003: Vanhaesebrouck Sofie; Allegaert Karel; Vanhole Christine; Devlieger Hugo; Gewillig Marc; Proesmans Willem
Pseudo-Bartter syndrome in a neonate on prostaglandin infusion.
European journal of pediatrics 2003;162(9):569-71.
2003: Allegaert K; Van de Velde M; Casteels I; Naulaers G; Vanhole C; Devlieger H
Cryotherapy for threshold retinopathy: perioperative management in a single center.
American journal of perinatology 2003;20(5):219-26.
2003: Allegaert Karel; Tibboel Dick; Naulaers Gunnar; Tison Denise; De Jonge Annick; Van Dijk Monique; Vanhole Christine; Devlieger Hugo
Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed.
European journal of clinical pharmacology 2003;59(2):87-90.
2003: Casteels Ingele; Verdonck Nancy; Allegaert Karel; Naulaers Gunnar; Devlieger Hugo
Structural and functional outcome in infants treated with cryotherapy for threshold retinopathy between 1989 and 1999.
Journal of pediatric ophthalmology and strabismus 2003;40(2):75-80.
2003: Allegaert Karel; Vanhole Christine; Casteels Ingele; Naulaers Gunnar; Debeer Anne; Cossey Veerle; Devlieger Hugo
Perinatal growth characteristics and associated risk of developing threshold retinopathy of prematurity.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 2003;7(1):34-7.
2003: Allegaert K; Verdonck N; Vanhole C; de Halleux V; Naulaers G; Cossey V; Devlieger H; Casteels I
Incidence, perinatal risk factors, visual outcome and management of threshold retinopathy.
Bulletin de la Société belge d'ophtalmologie 2003;(287):37-42.
2002: Allegaert K; Proesmans M; Naulaers G; Moerman P; Lerut T; Devlieger H
Neonatal transthoracic puncture in a case of congenital cystic adenomatoid malformation of the lung.
Journal of pediatric surgery 2002;37(10):1495-7.
2002: Allegaert K; Naulaers G; Gewillig M; Devlieger H
The use of methohexital during neonatal cardioversion.
Paediatric anaesthesia 2002;12(4):371-3.

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