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Karel Allegaert

Research Profile

Living Beings

Concepts & Ideas

Phenomena

Metabolic Clearance Rate

Chemicals & Drugs

Physiology

Gestational Age

Disorders

Procedures

Infusions, Intravenous

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Intensive Care Units, Neonatal

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Publications

TOP 3
Titia Hompes; Benedetta Izzi; Maarten Morreels; Anne Pexsters; Ganel Schops; Bernard Spitz; Rieta Van Bree; Bea Van den Bergh; Johan Verhaeghe; Koen Demyttenaere; Myriam Dom; Steffen Fieuws; Kathleen Freson; Edith Gellens; Vivette Glover; Karel Allegaert; Stephan Claes
Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood.
Karel Allegaert; Brian Anderson; Sinno Simons; Bart Van Overmeire
Paracetamol to induce ductus arteriosus closure: is it valid?
Heidi Schaballie; Isabelle Scheers; Lieve Sevenants; Christiane Vermylen; Luc Regal; Marleen Renard; Nicole Revencu; Tania Roskams; Karel Allegaert; Nancy Boeckx; Victoria Bordon; Xavier Bossuyt; David Cassiman; Anniek Corveleyn; Kris De Boeck; Filomeen Haerynck; Ilse Hoffman; Isabelle Meyts
Misdiagnosis as asphyxiating thoracic dystrophy and CMV-associated haemophagocytic lymphohistiocytosis in Shwachman-Diamond syndrome.

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All Publications

2013: Titia Hompes; Benedetta Izzi; Maarten Morreels; Anne Pexsters; Ganel Schops; Bernard Spitz; Rieta Van Bree; Bea Van den Bergh; Johan Verhaeghe; Koen Demyttenaere; Myriam Dom; Steffen Fieuws; Kathleen Freson; Edith Gellens; Vivette Glover; Karel Allegaert; Stephan Claes
Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood.
Journal of psychiatric research 2013;47(7):880-91.
2013: Karel Allegaert; Brian Anderson; Sinno Simons; Bart Van Overmeire
Paracetamol to induce ductus arteriosus closure: is it valid?
Archives of disease in childhood 2013;98(6):462-6.
2013: Heidi Schaballie; Isabelle Scheers; Lieve Sevenants; Christiane Vermylen; Luc Regal; Marleen Renard; Nicole Revencu; Tania Roskams; Karel Allegaert; Nancy Boeckx; Victoria Bordon; Xavier Bossuyt; David Cassiman; Anniek Corveleyn; Kris De Boeck; Filomeen Haerynck; Ilse Hoffman; Isabelle Meyts
Misdiagnosis as asphyxiating thoracic dystrophy and CMV-associated haemophagocytic lymphohistiocytosis in Shwachman-Diamond syndrome.
European journal of pediatrics 2013;172(5):613-22.
2013: Karel Allegaert; Jean-Paul Langhendries; John N van den Anker
Educational paper: do we need neonatal clinical pharmacologists?
European journal of pediatrics 2013;172(4):429-35.
2013: Karel Allegaert
Pediatric clinical pharmacology: an introduction to a series of educational papers.
European journal of pediatrics 2013;172(3):289-92.
2013: Aida Kulo; Nedzad Mulabegovic; Kristel Van Calsteren; Rene Verbesselt; Jan de Hoon; Sigfrid Hendrickx; Karel Allegaert
The impact of pregnancy on urinary ketorolac metabolites after single intravenous bolus.
European journal of drug metabolism and pharmacokinetics 2013;38(1):1-4.
2013: Aida Kulo; Liesbeth Lewi; Mariska Y Peeters; Anne Smits; Marc Van de Velde; Rene Verbesselt; Karel Allegaert; Jan de Hoon; Catherijne A J Knibbe
Pharmacokinetics of paracetamol and its metabolites in women at delivery and post-partum.
British journal of clinical pharmacology 2013;75(3):850-60.
2013: John van den Anker; Karel Allegaert
Perinatal pharmacology.
Seminars in fetal & neonatal medicine 2013;18(1):1-2.
2013: Karel Allegaert; Dick Tibboel; John N van den Anker
Pharmacological treatment of neonatal pain: in search of a new equipoise.
Seminars in fetal & neonatal medicine 2013;18(1):42-7.
2013: Karel Allegaert; Gunnar Naulaers; Sophie Vanhaesebrouck; Brian J Anderson
The paracetamol concentration-effect relation in neonates.
Paediatric anaesthesia 2013;23(1):45-50.
2013: Roosmarijn F W De Cock; Jan de Hoon; Catherijne A J Knibbe; Aida Kulo; Rene Verbesselt; Meindert Danhof; Karel Allegaert
Developmental pharmacokinetics of propylene glycol in preterm and term neonates.
British journal of clinical pharmacology 2013;75(1):162-71.
2012: Karel Allegaert; Liesbeth Thewissen; John N van den Anker
Remifentanil in neonates: a promising compound in search of its indications?
Pediatrics and neonatology 2012;53(6):387-8.
2012: Karel Allegaert; John N van den Anker
Creatinine-based vancomycin dosing regimens in neonates: there is more to consider than the variation in drug assay.
Pharmacotherapy 2012;32(9):e174; discussion e175.
2012: Sofie Ghekiere; Marc Van Ranst; Karel Allegaert; Catherine Cassiman; Veerle Cossey; Ingele Casteels
Ophthalmological findings in congenital cytomegalovirus infection: when to screen, when to treat?
Journal of pediatric ophthalmology and strabismus 2012;49(5):274-82.
2012: Chenguang Wang; Heleen J Blussé van Oud-Alblas; Karel Allegaert; Meindert Danhof; Elke H J Krekels; Mariska Y M Peeters; Dick Tibboel; Catherijne A J Knibbe
A bodyweight-dependent allometric exponent for scaling clearance across the human life-span.
Pharmaceutical research 2012;29(6):1570-81.
2012: Sophie Vanhaesebrouck; Christine Vanhole; Johan Maleux; Gunnar Naulaers; Claire Theyskens; Karel Allegaert; Ingele Casteels; Hans Daniëls; Francis de Zegher
Continuous glucose monitoring and retinopathy of prematurity.
European journal of ophthalmology 2012;22(3):436-40.
2012: G Pauwels; L Régal; Karel Allegaert; A Meulemans
Risk factors for elevated levels of 17-hydroxyprogesterone during neonatal intensive care unit admission.
Acta clinica Belgica 2012;67(2):88-93.
2012: Karel Allegaert; Sigfrid Hendrickx; J Kelchtermans; A Kulo; A Smits; Kristel Van Calsteren; Marc Van de Velde
Paracetamol and ketorolac pharmacokinetics and metabolism at delivery and during postpartum.
Acta anaesthesiologica Belgica 2012;63(3):121-5.
2012: Aida Kulo; Gunnar Naulaers; Anne Smits; Jan de Hoon; Karel Allegaert
Biochemical tolerance during low dose propylene glycol exposure in neonates: A formulation-controlled evaluation.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2012;20(1):5.
2012: Anne Smits; Jan de Hoon; Aida Kulo; Karel Allegaert
Pharmacokinetics of drugs in neonates: pattern recognition beyond compound specific observations.
Current pharmaceutical design 2012;18(21):3119-46.
2012: Karel Allegaert; Anne Smits; Johannes N van den Anker
Physiologically based pharmacokinetic modeling in pediatric drug development: a clinician's request for a more integrated approach.
Journal of biomedicine & biotechnology 2012;2012():103763.
2012: Maissa Rayyan; Hugo Devlieger; Frank Jochum; Karel Allegaert
Short-term use of parenteral nutrition with a lipid emulsion containing a mixture of soybean oil, olive oil, medium-chain triglycerides, and fish oil: a randomized double-blind study in preterm infants.
JPEN. Journal of parenteral and enteral nutrition 2012;36(1 Suppl):81S-94S.
2012: Liesbeth Thewissen; Karel Allegaert
Inotropic support in the NICU: ever more compounds in search of guidance? Commentary on J. Esch et al.: differential hemodynamic effects of levosimendan in a porcine model of neonatal hypoxia-reoxygenation (Neonatology 2012;101:192–200) and M.P. De Carolis et al.: levosimendan in two neonates with ischemic heart failure and pulmonary hypertension (Neonatology 2012;101:201–205).
Neonatology 2012;101(3):206-9.
2011: Karel Allegaert; John van den Anker
Pharmacokinetics and pharmacodynamics of intravenous acetaminophen in neonates.
Expert review of clinical pharmacology 2011;4(6):713-8.
2011: Anne Smits; Karel Allegaert
Perinatal pharmacology: applications for neonatal neurology.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2011;15(6):478-86.
2011: Isabel George; Elena N Levtchenko; Djalila Mekahli; Maissa Rayyan; Karel Allegaert
Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates.
Pediatric nephrology (Berlin, Germany) 2011;26(10):1843-9.
2011: Philip Dekoninck; Karel Allegaert; Ana Martin Ancel; Eduard Gratacos; Paul Lewi; Kypros Nicolaides; Jute Richter; Tim Van Mieghem; Jan Deprest
Results of fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia and the set up of the randomized controlled TOTAL trial.
Early human development 2011;87(9):619-24.
2011: C Tayman; A Van Schepdael; E Adams; Karel Allegaert; A Debeer; M N El-Attug; A Smits
Quantification of amikacin in bronchial epithelial lining fluid in neonates.
Antimicrobial agents and chemotherapy 2011;55(9):3990-3.
2011: Karel Allegaert
Mechanism based medicine in infancy: complex interplay between developmental pharmacology and pharmacogenetics.
International journal of clinical pharmacy 2011;33(3):473-4.
2011: Liesbeth Thewissen; Karel Allegaert
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
Archives of disease in childhood. Education and practice edition 2011;96(3):112-8.
2011: Karel Allegaert; Greta M Palmer; Brian J Anderson
The pharmacokinetics of intravenous paracetamol in neonates: size matters most.
Archives of disease in childhood 2011;96(6):575-80.
2011: Lynn Hopchet; Aida Kulo; Maissa Rayyan; Rene Verbesselt; Christine Vanhole; Jan de Hoon; Karel Allegaert
Does intravenous paracetamol administration affect body temperature in neonates?
Archives of disease in childhood 2011;96(3):301-4.
2011: Karel Allegaert; Alain Rochette; Francis Veyckemans
Developmental pharmacology of tramadol during infancy: ontogeny, pharmacogenetics and elimination clearance.
Paediatric anaesthesia 2011;21(3):266-73.
2011: E Done; Karel Allegaert; P Lewi; Jacques Jani; L Gucciardo; Tim Van Mieghem; E Gratacos; Roland Devlieger; D Van Schoubroeck; Jan Deprest
Maternal hyperoxygenation test in fetuses undergoing FETO for severe isolated congenital diaphragmatic hernia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2011;37(3):264-71.
2011: Karel Allegaert; Mariska Y M Peeters; Catherijne Knibbe
Propofol in (pre)term neonates: consider the extensive interindividual variability in clearance within the neonatal population.
Paediatric anaesthesia 2011;21(2):174-5.
2010: Karel Allegaert; Sophie Vanhaesebrouck; Aida Kulo; Katrien Cosaert; Rene Verbesselt; Anne Debeer; Jan de Hoon
Prospective assessment of short-term propylene glycol tolerance in neonates.
Archives of disease in childhood 2010;95(12):1054-8.
2010: Karel Allegaert; Gunnar Naulaers
Gabapentin as part of multimodal analgesia in a newborn with epidermolysis bullosa.
Paediatric anaesthesia 2010;20(10):972-3.
2010: Brian J Anderson; Karel Allegaert
The pharmacology of anaesthetics in the neonate.
Best practice & research. Clinical anaesthesiology 2010;24(3):419-31.
2010: Karel Allegaert; Gunnar Naulaers
Haemodynamics of intravenous paracetamol in neonates.
European journal of clinical pharmacology 2010;66(9):855-8.
2010: Joke Vanderhaegen; Gunnar Naulaers; Sabine Van Huffel; Christine Vanhole; Karel Allegaert
Cerebral and systemic hemodynamic effects of intravenous bolus administration of propofol in neonates.
Neonatology 2010;98(1):57-63.
2010: Jeroen Breckpot; Bernard Thienpont; Hilde Peeters; Thomy de Ravel; Amihood Singer; Maissa Rayyan; Karel Allegaert; Christine Vanhole; Benedicte Eyskens; Joris Robert Vermeesch; Marc Gewillig; koenraad devriendt
Array comparative genomic hybridization as a diagnostic tool for syndromic heart defects.
The Journal of pediatrics 2010;156(5):810-7, 817.e1-817.e4.
2010: Mariska Y M Peeters; Karel Allegaert; Heleen J Blussé van Oud-Alblas; Massimo Cella; Dick Tibboel; Meindert Danhof; Catherijne A J Knibbe
Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model.
Clinical pharmacokinetics 2010;49(4):269-75.
2010: Karel Allegaert; I Casteels; Dick Tibboel
Pain management during eye examinations for retinopathy of prematurity: what about procedural adaptations to blunt the pain response?
Acta paediatrica (Oslo, Norway : 1992) 2010;99(4):488-9.
2010: B Mijović; M Silva; B R H Van den Bergh; Karel Allegaert; JM Aerts; Daniel Berckmans; Sabine Van Huffel
Assessment of pain expression in infant cry signals using empirical mode decomposition.
Methods of information in medicine 2010;49(5):448-52.
2010: Mitchell Silva; Bogdan Mijovic; Bea R H Van den Bergh; Karel Allegaert; Jean-Marie Aerts; Sabine Van Huffel; Daniel Berckmans
Decoupling between fundamental frequency and energy envelope of neonate cries.
Early human development 2010;86(1):35-40.
2010: Tim Van Mieghem; Elisa Doné; Léonardo Gucciardo; Philipp Klaritsch; Karel Allegaert; Rita Van Bree; Liesbeth Lewi; Jan Deprest
Amniotic fluid markers of fetal cardiac dysfunction in twin-to-twin transfusion syndrome.
American journal of obstetrics and gynecology 2010;202(1):48.e1-7.
2009: Karel Allegaert
Aminoglycoside pharmacokinetics in neonates: the need to search for covariates of variability in addition to case descriptions.
Acta paediatrica (Oslo, Norway : 1992) 2009;98(10):1546; author reply 1546-7.
2009: Mieke M Cannie; Jacques Jani; Frederik De Keyzer; Karel Allegaert; Steven Dymarkowski; Jan Deprest
Evidence and patterns in lung response after fetal tracheal occlusion: clinical controlled study.
Radiology 2009;252(2):526-33.
2009: Karel Allegaert; Sophie Vanhaesebrouck; Rene Verbesselt; John N van den Anker
In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age.
Therapeutic drug monitoring 2009;31(4):411-5.
2009: Sophie Vanhaesebrouck; Veerle Cossey; Katrien Cosaert; Karel Allegaert; Gunnar Naulaers
Cardiorespiratory depression and hyperglycemia after unintentional ingestion of brimonidine in a neonate.
European journal of ophthalmology 2009;19(4):694-5.
2009: Karel Allegaert; Francis Veyckemans; Dick Tibboel
Clinical practice: analgesia in neonates.
European journal of pediatrics 2009;168(7):765-70.
2009: Jan A Deprest; Eduardo Gratacos; Kypros Nicolaides; Elise Done; Tim Van Mieghem; Leonardo Gucciardo; Filip Claus; Anne Debeer; Karel Allegaert; Irwin Reiss; Dick Tibboel
Changing perspectives on the perinatal management of isolated congenital diaphragmatic hernia in Europe.
Clinics in perinatology 2009;36(2):329-47, ix.
2009: Karel Allegaert; Kenneth F Ilett; Gideon Koren
Tramadol withdrawal in a neonate: only one of the clinical presentations to be anticipated...
European journal of clinical pharmacology 2009;65(6):643-4; author reply 645.
2009: Karel Allegaert
Is propofol the perfect hypnotic agent for procedural sedation in neonates?
Current clinical pharmacology 2009;4(2):84-6.
2009: Brian J Anderson; Karel Allegaert
Intravenous neonatal paracetamol dosing: the magic of 10 days.
Paediatric anaesthesia 2009;19(4):289-95.
2009: Karel Allegaert; Tim van Mieghem; Rene Verbesselt; Jan de Hoon; Maissa Rayyan; Roland Devlieger; Jan Deprest; Brian J Anderson
Cefazolin pharmacokinetics in maternal plasma and amniotic fluid during pregnancy.
American journal of obstetrics and gynecology 2009;200(2):170.e1-7.
2009: Karel Allegaert
The impact of ibuprofen or indomethacin on renal drug clearance in neonates.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2009;22 Suppl 3():88-91.
2009: Karel Allegaert; Tim Van Mieghem; Rene Verbesselt; Christine Vanhole; Roland Devlieger; Veerle Cossey; Jan Deprest; Jan de Hoon
Cefazolin plasma protein binding saturability during pregnancy.
Methods and findings in experimental and clinical pharmacology 2009;31(1):25-8.
2008: Karel Allegaert; Isabelle Scheers; Veerle Cossey; Brian J Anderson
Covariates of amikacin clearance in neonates: the impact of postnatal age on predictability.
Drug metabolism letters 2008;2(4):286-9.
2008: Mieke Cannie; Jacques Jani; J Meersschaert; Karel Allegaert; E Done'; Guy Marchal; Jan Deprest; Steven Dymarkowski
Prenatal prediction of survival in isolated diaphragmatic hernia using observed to expected total fetal lung volume determined by magnetic resonance imaging based on either gestational age or fetal body volume.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;32(5):633-9.
2008: Karel Allegaert; I Scheers; E Adams; G Brajanoski; Veerle Cossey; Brian J Anderson
Cerebrospinal fluid compartmental pharmacokinetics of amikacin in neonates.
Antimicrobial agents and chemotherapy 2008;52(6):1934-9.
2008: Karel Allegaert; Ron van Schaik; Steve Vermeersch; Rene Verbesselt; Veerle Cossey; Christine Vanhole; Marianne van Fessem; Jan de Hoon; John N van den Anker
Postmenstrual age and CYP2D6 polymorphisms determine tramadol o-demethylation in critically ill neonates and infants.
Pediatric research 2008;63(6):674-9.
2008: Gordana Brajanoski; Jos Hoogmartens; Karel Allegaert; Erwin Adams
Determination of amikacin in cerebrospinal fluid by high-performance liquid chromatography with pulsed electrochemical detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;867(1):149-52.
2008: Karel Allegaert; Maissa Rayyan; Thomas De Rijdt; Frank Van Beek; Gunnar Naulaers
Hepatic tolerance of repeated intravenous paracetamol administration in neonates.
Paediatric anaesthesia 2008;18(5):388-92.
2008: Karel Allegaert; Christine Vanhole; S Vermeersch; Maissa Rayyan; Rene Verbesselt; Jan de Hoon
Both postnatal and postmenstrual age contribute to the interindividual variability in tramadol glucuronidation in neonates.
Early human development 2008;84(5):325-30.
2008: Karel Allegaert; John N van den Anker; Jan de Hoon; Ron van Schaik; Anne Debeer; Dick Tibboel; Gunnar Naulaers; B J Anderson
Covariates of tramadol disposition in the first months of life.
British journal of anaesthesia 2008;100(4):525-32.
2008: Sofie Staelens; Mieke Van den Driessche; Denis Barclay; Anne-Lise Carrié-Faessler; Ferdinand Haschke; Kristin Verbeke; Hilde Vandebroek; Karel Allegaert; Bart Van Overmeire; Mieke Van Damme; Gigi Veereman-Wauters
Gastric emptying in healthy newborns fed an intact protein formula, a partially and an extensively hydrolysed formula.
Clinical nutrition (Edinburgh, Scotland) 2008;27(2):264-8.
2008: Sophie Vanhaesebrouck; Christine Vanhole; F de Zegher; Karel Allegaert
Influence of duration of parenteral nutrition on retinopathy of prematurity.
Archives of disease in childhood. Fetal and neonatal edition 2008;93(2):F170.
2008: Karel Allegaert; Jan de Hoon; Gunnar Naulaers; Marc Van de Velde
Neonatal clinical pharmacology: recent observations of relevance for anaesthesiologists.
Acta anaesthesiologica Belgica 2008;59(4):283-8.
2008: Karel Allegaert; Rene Verbesselt; Gunnar Naulaers; John N van den Anker; Maissa Rayyan; Anne Debeer; Jan de Hoon
Developmental pharmacology: neonates are not just small adults...
Acta clinica Belgica 2008;63(1):16-24.
2007: Karel Allegaert; Mariska Y M Peeters; Rene Verbesselt; Dick Tibboel; Gunnar Naulaers; Jan de Hoon; Catherijne A J Knibbe
Inter-individual variability in propofol pharmacokinetics in preterm and term neonates.
British journal of anaesthesia 2007;99(6):864-70.
2007: Karel Allegaert; Jan de Hoon; Rene Verbesselt; Gunnar Naulaers; Isabelle Murat
Maturational pharmacokinetics of single intravenous bolus of propofol.
Paediatric anaesthesia 2007;17(11):1028-34.
2007: Karel Allegaert; Isabelle Murat; Brian J Anderson
Not all intravenous paracetamol formulations are created equal...
Paediatric anaesthesia 2007;17(8):811-2.
2007: Karel Allegaert; Marc Van de Velde
Blunted inflammatory and faster clinical recovery following laser treatment compared to cryotherapy.
Archives of disease in childhood 2007;92(7):655.
2007: Karel Allegaert; Brian J Anderson; John N van den Anker; Sophie Vanhaesebrouck; Francis de Zegher
Renal drug clearance in preterm neonates: relation to prenatal growth.
Therapeutic drug monitoring 2007;29(3):284-91.
2007: Karel Allegaert; Rene Verbesselt; Maissa Rayyan; Anne Debeer; Jan de Hoon
Urinary metabolites to assess in vivo ontogeny of hepatic drug metabolism in early neonatal life.
Methods and findings in experimental and clinical pharmacology 2007;29(4):251-6.
2007: Karel Allegaert; Marc Van de Velde; Ingele Casteels
Variation in management during and after retinal surgery for retinopathy of prematurity.
Eye (London, England) 2007;21(5):679-80.
2007: Gunnar Naulaers; Hans Daniels; Karel Allegaert; Maissa Rayyan; Anne Debeer; Hugo Devlieger
Cardiorespiratory events recorded on home monitors: the effect of prematurity on later serious events.
Acta paediatrica (Oslo, Norway : 1992) 2007;96(2):195-8.
2007: Karel Allegaert; John N van den Anker; Gunnar Naulaers; Jan de Hoon
Determinants of drug metabolism in early neonatal life.
Current clinical pharmacology 2007;2(1):23-9.
2007: Karel Allegaert; Sinno H Simons; Christine Vanhole; Dick Tibboel
Developmental pharmacokinetics of opioids in neonates.
Journal of opioid management 2007;3(1):59-64.
2007: Maissa Rayyan; Karel Allegaert
Pharmacotherapy during neonatal extracorporeal membrane oxygenation: toward an evidence-based approach.
Critical care (London, England) 2007;11(1):107.
2007: Brian J Anderson; Karel Allegaert; John N van den Anker; Veerle Cossey; Nick Holford
Vancomycin pharmacokinetics in preterm neonates and the prediction of adult clearance.
British journal of clinical pharmacology 2007;63(1):75-84.
2006: Karel Allegaert; Brian J Anderson
Interindividual variability of aminoglycoside pharmacokinetics in preterm neonates at birth.
European journal of clinical pharmacology 2006;62(12):1011-2.
2006: Brian J Anderson; Karel Allegaert; Nick Holford
Population clinical pharmacology of children: modelling covariate effects.
European journal of pediatrics 2006;165(12):819-29.
2006: Brian J Anderson; Karel Allegaert; Nick Holford
Population clinical pharmacology of children: general principles.
European journal of pediatrics 2006;165(11):741-6.
2006: Karel Allegaert; Maissa Rayyan; B J Anderson
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Methods and findings in experimental and clinical pharmacology 2006;28(8):519-22.
2006: Karel Allegaert; Anne Debeer
Circulatory effects of antenatal betamethasone therapy in low birthweight infants.
Archives of disease in childhood. Fetal and neonatal edition 2006;91(5):F389-90.
2006: Karel Allegaert; John N van den Anker; Anne Debeer; Veerle Cossey; Rene Verbesselt; Dick Tibboel; Hugo Devlieger; Jan de Hoon
Maturational changes in the in vivo activity of CYP3A4 in the first months of life.
International journal of clinical pharmacology and therapeutics 2006;44(7):303-8.
2006: Karel Allegaert; Liesbeth Lewi; Gunnar Naulaers; Lieven Lagae
Levetiracetam pharmacokinetics in neonates at birth.
Epilepsia 2006;47(6):1068-9.
2006: Karel Allegaert; Anne Debeer; Veerle Cossey; Maissa Rayyan; Hugo Devlieger
Dopamine is not an independent risk factor for reduced amikacin clearance in extremely low-birth-weight infants.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2006;7(2):143-6.
2006: Karel Allegaert; Marc Van de Velde; Anne Debeer; Ingele Casteels; Hugo Devlieger
Cryotherapy versus laser photocoagulation for threshold retinopathy of prematurity: impact on early postoperative clinical recovery.
Bulletin de la Société belge d'ophtalmologie 2006;(300):7-10.
2006: Karel Allegaert; Maissa Rayyan; Jan de Hoon; Dick Tibboel; Rene Verbesselt; Gunnar Naulaers; John N van den Anker; Hugo Devlieger
Contribution of glucuronidation to tramadol disposition in early neonatal life.
Basic & clinical pharmacology & toxicology 2006;98(1):110-2.
2006: Karel Allegaert; Brian J Anderson; Veerle Cossey; Nick Holford
Limited predictability of amikacin clearance in extreme premature neonates at birth.
British journal of clinical pharmacology 2006;61(1):39-48.
2005: Karel Allegaert; John N van den Anker; Rene Verbesselt; Jan de Hoon; Christine Vanhole; Dick Tibboel; Hugo Devlieger
O-demethylation of tramadol in the first months of life.
European journal of clinical pharmacology 2005;61(11):837-42.
2005: Karel Allegaert; Christine Vanhole; Jan de Hoon; Jean Pierre Guignard; Dick Tibboel; Hugo Devlieger; Bart Van Overmeire
Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates.
Pediatric nephrology (Berlin, Germany) 2005;20(11):1557-61.
2005: Karel Allegaert; Jan de Hoon; Rene Verbesselt; Christine Vanhole; Hugo Devlieger; Dick Tibboel
Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates.
Acta paediatrica (Oslo, Norway : 1992) 2005;94(9):1273-9.
2005: Karel Allegaert; Hugo Devlieger; Ingele Casteels
Reduced inflammatory response after laser photocoagulation compared with cryoablation for threshold retinopathy of prematurity.
Journal of pediatric ophthalmology and strabismus 2005;42(5):264-6.
2005: Karel Allegaert; B J Anderson; Rene Verbesselt; Anne Debeer; Jan de Hoon; Hugo Devlieger; John N van den Anker; Dick Tibboel
Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.
British journal of anaesthesia 2005;95(2):231-9.
2005: Karel Allegaert; Hans Daniels; Gunnar Naulaers; Dick Tibboel; Hugo Devlieger
Pharmacodynamics of chloral hydrate in former preterm infants.
European journal of pediatrics 2005;164(7):403-7.
2005: Karel Allegaert; Veerle Cossey; Anne Debeer; Jean-Paul Langhendries; Bart Van Overmeire; Jan de Hoon; Hugo Devlieger
The impact of ibuprofen on renal clearance in preterm infants is independent of the gestational age.
Pediatric nephrology (Berlin, Germany) 2005;20(6):740-3.
2005: Brian J Anderson; Gerard Pons; Elisabeth Autret-Leca; Karel Allegaert; Eric Boccard
Pediatric intravenous paracetamol (propacetamol) pharmacokinetics: a population analysis.
Paediatric anaesthesia 2005;15(4):282-92.
2005: Karel Allegaert; Jan de Hoon; Rene Verbesselt; Hugo Devlieger; Dick Tibboel
Tramadol concentrations in blood and in cerebrospinal fluid in a neonate.
European journal of clinical pharmacology 2005;60(12):911-3.
2005: Karel Allegaert; Jan de Hoon; Bart Van Overmeire; Hugo Devlieger
Clinical pharmacology of non opioid analgesics in neonates.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2005;67(5-6):289-315.
2005: Karel Allegaert; Hugo Devlieger; Dominiek Bulckaert; Gunnar Naulaers; Paul Casaer; Dick Tibboel
Variability in pain expression characteristics in former preterm infants.
Journal of perinatal medicine 2005;33(5):442-8.
2005: Gunnar Naulaers; G Delanghe; Karel Allegaert; Anne Debeer; Veerle Cossey; Christine Vanhole; Paul Casaer; Hugo Devlieger; Bart Van Overmeire
Ibuprofen and cerebral oxygenation and circulation.
Archives of disease in childhood. Fetal and neonatal edition 2005;90(1):F75-6.
2004: Karel Allegaert; Christine Vanhole; Maria van Helvoirt; Sophie Vanhaesebrouck; Marc Gewillig; Anne Debeer; Hugo Devlieger; Francis de Zegher
Association of patent ductus arteriosus and severe hypothyroidism in term newborns: coincidence or causal?
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(6):339-41.
2004: Bart Van Overmeire; Karel Allegaert; Alexandra Casaer; Christian Debauche; Wim Decaluwé; Ann Jespers; Joost Weyler; Inge Harrewijn; Jean-Paul Langhendries
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.
Lancet 2004;364(9449):1945-9.
2004: Piet Vanhaesebrouck; Karel Allegaert; Jean Bottu; Christian Debauche; Hugo Devlieger; Martine Docx; Anne François; Dominique Haumont; Jacques Lombet; Jean-Michel Rigo; Koenraad Smets; Inge Vanherreweghe; Bart Van Overmeire; Patrick Van Reempts
The EPIBEL study: outcomes to discharge from hospital for extremely preterm infants in Belgium.
Pediatrics 2004;114(3):663-75.
2004: Christine Vanhole; F Jannes; M Vrancken; Gunnar Naulaers; Karel Allegaert; L Willems; Hugo Devlieger
Continuous infusion of medications in very low birth weight infants.
European journal of clinical pharmacology 2004;60(5):383-6.
2004: Maissa Rayyan; Gunnar Naulaers; Hans Daniels; Karel Allegaert; Anne Debeer; Hugo Devlieger
Characteristics of respiratory syncytial virus-related apnoea in three infants.
Acta paediatrica (Oslo, Norway : 1992) 2004;93(6):847-9.
2004: Karel Allegaert; Brian J Anderson; Gunnar Naulaers; Jan de Hoon; Rene Verbesselt; Anne Debeer; Hugo Devlieger; Dick Tibboel
Intravenous paracetamol (propacetamol) pharmacokinetics in term and preterm neonates.
European journal of clinical pharmacology 2004;60(3):191-7.
2004: Karel Allegaert; Gunnar Naulaers; Anne Debeer; Luc Breysem; I Ferens; Christine Vanhole; Hugo Devlieger; Dick Tibboel
The use of methohexital during chest tube removal in neonates.
Paediatric anaesthesia 2004;14(4):308-12.
2004: Coranne D Tesselaar; Roelf R Postema; Marieke F van Dooren; Karel Allegaert; Dick Tibboel
Congenital diaphragmatic hernia and situs inversus totalis.
Pediatrics 2004;113(3 Pt 1):e256-8.
2004: Karel Allegaert; Rene Verbesselt; H Devlieger; Jan de Hoon; D Tibboel
Cerebrospinal fluid pharmacokinetics of paracetamol after intravenous propacetamol in a former preterm infant.
British journal of clinical pharmacology 2004;57(2):224-5.
2004: Karel Allegaert; Veerle Cossey; Gunnar Naulaers; Christine Vanhole; Hugo Devlieger; Ingele Casteels
Dopamine is an indicator but not an independent risk factor for grade 3 retinopathy of prematurity in extreme low birthweight infants.
The British journal of ophthalmology 2004;88(2):309-10.
2004: Karel Allegaert; Veerle Cossey; Jean-Paul Langhendries; Gunnar Naulaers; Christine Vanhole; Hugo Devlieger; Bart Van Overmeire
Effects of co-administration of ibuprofen-lysine on the pharmacokinetics of amikacin in preterm infants during the first days of life.
Biology of the neonate 2004;86(3):207-11.
2004: Karel Allegaert; Caroline D van der Marel; Anne Debeer; M A L Pluim; Richard A van Lingen; Christine Vanhole; Dick Tibboel; Hugo Devlieger
Pharmacokinetics of single dose intravenous propacetamol in neonates: effect of gestational age.
Archives of disease in childhood. Fetal and neonatal edition 2004;89(1):F25-8.
2004: Karel Allegaert; Marc Miserez; Toni Lerut; Gunnar Naulaers; Christine Vanhole; Hugo Devlieger
Methemoglobinemia and hemolysis after enteral administration of methylene blue in a preterm infant: relevance for pediatric surgeons.
Journal of pediatric surgery 2004;39(1):E35-7.
2003: Karel Allegaert; Ingele Casteels; Veerle Cossey; Hugo Devlieger
Retinopathy of prematurity: any difference in risk factors between a high and low risk population?
European journal of ophthalmology 2003;13(9-10):784-8.
2003: Sophie Vanhaesebrouck; Karel Allegaert; Christine Vanhole; Hugo Devlieger; Marc Gewillig; Willem Proesmans
Pseudo-Bartter syndrome in a neonate on prostaglandin infusion.
European journal of pediatrics 2003;162(9):569-71.
2003: Karel Allegaert; Marc Van de Velde; Ingele Casteels; Gunnar Naulaers; Christine Vanhole; Hugo Devlieger
Cryotherapy for threshold retinopathy: perioperative management in a single center.
American journal of perinatology 2003;20(5):219-26.
2003: Karel Allegaert; Dick Tibboel; Gunnar Naulaers; Denise Tison; Annick De Jonge; Monique Van Dijk; Christine Vanhole; Hugo Devlieger
Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed.
European journal of clinical pharmacology 2003;59(2):87-90.
2003: Ingele Casteels; Nancy Verdonck; Karel Allegaert; Gunnar Naulaers; Hugo Devlieger
Structural and functional outcome in infants treated with cryotherapy for threshold retinopathy between 1989 and 1999.
Journal of pediatric ophthalmology and strabismus 2003;40(2):75-80.
2003: Karel Allegaert; Christine Vanhole; Ingele Casteels; Gunnar Naulaers; Anne Debeer; Veerle Cossey; Hugo Devlieger
Perinatal growth characteristics and associated risk of developing threshold retinopathy of prematurity.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus 2003;7(1):34-7.
2003: Karel Allegaert; N Verdonck; Christine Vanhole; V de Halleux; Gunnar Naulaers; Veerle Cossey; Hugo Devlieger; Ingele Casteels
Incidence, perinatal risk factors, visual outcome and management of threshold retinopathy.
Bulletin de la Société belge d'ophtalmologie 2003;(287):37-42.
2002: Karel Allegaert; Marijke Proesmans; Gunnar Naulaers; P Moerman; Toni Lerut; Hugo Devlieger
Neonatal transthoracic puncture in a case of congenital cystic adenomatoid malformation of the lung.
Journal of pediatric surgery 2002;37(10):1495-7.
2002: Karel Allegaert; Gunnar Naulaers; M Gewillig; Hugo Devlieger
The use of methohexital during neonatal cardioversion.
Paediatric anaesthesia 2002;12(4):371-3.