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Edward Conway

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Vanessa Coremans; Tariq Ahmed; Detlef Balschun; Rudi D'Hooge; Astrid DeVriese; Jonathan Cremer; Flavia Antonucci; Michaël Moons; Veerle Baekelandt; Veerle Reumers; Harold Cremer; Amelia Eisch; Diane Lagace; Tom Janssens; Yuri Bozzi; Matteo Caleo; Edward M Conway
Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin.
Mieke Delvaeye; Edward M Conway
Coagulation and innate immune responses: can we view them separately?
Mieke Delvaeye; Marina Noris; Astrid De Vriese; Charles T Esmon; Naomi L Esmon; Gary Ferrell; Jurgen Del-Favero; Stephane Plaisance; Bart Claes; Diether Lambrechts; Carla Zoja; Giuseppe Remuzzi; Edward M Conway
Thrombomodulin mutations in atypical hemolytic-uremic syndrome.

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All Publications

2010: Vanessa Coremans; Tariq Ahmed; Detlef Balschun; Rudi D'Hooge; Astrid DeVriese; Jonathan Cremer; Flavia Antonucci; Michaël Moons; Veerle Baekelandt; Veerle Reumers; Harold Cremer; Amelia Eisch; Diane Lagace; Tom Janssens; Yuri Bozzi; Matteo Caleo; Edward M Conway
Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin.
BMC neuroscience 2010;11():2.
2009: Mieke Delvaeye; Edward M Conway
Coagulation and innate immune responses: can we view them separately?
Blood 2009;114(12):2367-74.
2009: Mieke Delvaeye; Marina Noris; Astrid De Vriese; Charles T Esmon; Naomi L Esmon; Gary Ferrell; Jurgen Del-Favero; Stephane Plaisance; Bart Claes; Diether Lambrechts; Carla Zoja; Giuseppe Remuzzi; Edward M Conway
Thrombomodulin mutations in atypical hemolytic-uremic syndrome.
The New England journal of medicine 2009;361(4):345-57.
2009: Mieke Delvaeye; Astrid De Vriese; Femke Zwerts; Inge Betz; Michael Moons; Monica Autiero; Edward M Conway
Role of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis.
BMC developmental biology 2009;9():25.
2008: Nele Geudens; Marlies Van de Wouwer; Bart M Vanaudenaerde; R Vos; Caroline Van De Wauwer; Geert M Verleden; Erik Verbeken; Toni Lerut; Dirk E M Van Raemdonck; Edward M Conway
The lectin-like domain of thrombomodulin protects against ischaemia-reperfusion lung injury.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(4):862-70.
2008: Anne Angelillo-Scherrer; Laurent Burnier; Diether Lambrechts; Richard J Fish; Marc Tjwa; Stephane Plaisance; Rocco Sugamele; Maria DeMol; Eduardo Martinez-Soria; Patrick H Maxwell; Greg Lemke; Stephen P Goff; Glenn K Matsushima; Henry Earp; Marc Chanson; Désiré Collen; Shozo Izui; Marc Schapira; Edward M Conway; Peter Carmeliet
Role of Gas6 in erythropoiesis and anemia in mice.
The Journal of clinical investigation 2008;118(2):583-96.
2008: Nele Kindt; Axel Menzebach; Marlies Van de Wouwer; Inge Betz; Astrid De Vriese; Edward M Conway
Protective role of the inhibitor of apoptosis protein, survivin, in toxin-induced acute renal failure.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(2):510-21.
2007: Femke Zwerts; Florea Lupu; Astrid De Vriese; Saskia Pollefeyt; Lieve Moons; Rachel A Altura; Yuying Jiang; Patrick H Maxwell; Peter Hill; Hideyasu Oh; Claus Rieker; Désiré Collen; Simon J Conway; Edward M Conway
Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure.
Blood 2007;109(11):4742-52.
2006: Marlies Van de Wouwer; Stephane Plaisance; Astrid De Vriese; E Waelkens; Désiré Collen; J Persson; M R Daha; Edward M Conway
The lectin-like domain of thrombomodulin interferes with complement activation and protects against arthritis.
Journal of thrombosis and haemostasis : JTH 2006;4(8):1813-24.
2006: Diether Lambrechts; Peggy Lafuste; Peter Carmeliet; Edward M Conway
Another angiogenic gene linked to amyotrophic lateral sclerosis.
Trends in molecular medicine 2006;12(8):345-7.
2005: Annelii Ny; Marta Koch; Martin Schneider; Elke Neven; Ricky T Tong; Sunit Maity; Christian Fischer; Stephane Plaisance; Diether Lambrechts; Christophe Héligon; Sven Terclavers; Malgorzata Ciesiolka; Roland Kälin; Wing Yan Man; Irena Senn; Sabine Wyns; Florea Lupu; André Brändli; Kris Vleminckx; Désiré Collen; Mieke Dewerchin; Edward M Conway; Lieve Moons; Rakesh K Jain; Peter Carmeliet
A genetic Xenopus laevis tadpole model to study lymphangiogenesis.
Nature medicine 2005;11(9):998-1004.
2005: Yuying Jiang; Alain de Bruin; Hugo Caldas; Jason Fangusaro; John Hayes; Edward M Conway; Michael L Robinson; Rachel A Altura
Essential role for survivin in early brain development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(30):6962-70.
2005: Hugo Caldas; Yuying Jiang; Michael P Holloway; Jason Fangusaro; Csaba Mahotka; Edward M Conway; Rachel A Altura
Survivin splice variants regulate the balance between proliferation and cell death.
Oncogene 2005;24(12):1994-2007.
2005: Anne Angelillo-Scherrer; Laurent Burnier; Nathalie Flores; Pierre Savi; Maria DeMol; Paul Schaeffer; Jean-Marc Herbert; Greg Lemke; Stephen P Goff; Glenn K Matsushima; Henry Earp; Christian Vesin; Marc F Hoylaerts; Stephane Plaisance; Désiré Collen; Edward M Conway; Bernhard Wehrle-Haller; Peter Carmeliet
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
The Journal of clinical investigation 2005;115(2):237-46.
2005: Erik Storkebaum; Diether Lambrechts; Mieke Dewerchin; Maria-Paz Moreno-Murciano; Saskia Appelmans; Hideyasu Oh; Philip Van Damme; Bart Rutten; Wing Yan Man; Maria De Mol; Sabine Wyns; David Manka; Kristel Vermeulen; Ludo Van Den Bosch; Nico Mertens; Christoph Schmitz; Wim Robberecht; Edward M Conway; Désiré Collen; Lieve Moons; Peter Carmeliet
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.
Nature neuroscience 2005;8(1):85-92.
2004: Marlies Van de Wouwer; Désiré Collen; Edward M Conway
Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1374-83.
2004: Marlies Van de Wouwer; Edward M Conway
Novel functions of thrombomodulin in inflammation.
Critical care medicine 2004;32(5 Suppl):S254-61.
2004: Edward M Conway; Peter Carmeliet
The diversity of endothelial cells: a challenge for therapeutic angiogenesis.
Genome biology 2004;5(2):207.
2003: Edward M Conway
Angiogenesis: a link to thrombosis in athero-thrombotic disease.
Pathophysiology of haemostasis and thrombosis 2003;33(5-6):241-8.
2003: Edward M Conway; Femke Zwerts; Veerle Van Eygen; Astrid DeVriese; Nobuo Nagai; Wei Luo; Désiré Collen
Survivin-dependent angiogenesis in ischemic brain: molecular mechanisms of hypoxia-induced up-regulation.
The American journal of pathology 2003;163(3):935-46.
2003: Monica Autiero; Johannes Waltenberger; David Communi; Andrea Kranz; Lieve Moons; Diether Lambrechts; Jens Kroll; Stephane Plaisance; Maria De Mol; Françoise Bono; Stefanie Kliche; Guido Fellbrich; Kurt Ballmer-Hofer; Domenico Maglione; Ulrike Mayr-Beyrle; Mieke Dewerchin; Saskia Dombrowski; Danica Stanimirovic; Paul van Hummelen; Christoph Dehio; Daniel J Hicklin; Graziella Persico; Jean-Marc Herbert; David Communi; Masabumi Shibuya; Désiré Collen; Edward M Conway; Peter Carmeliet
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1.
Nature medicine 2003;9(7):936-43.
2002: Edward M Conway; Marlies Van de Wouwer; Saskia Pollefeyt; Kerstin Jurk; Hugo Van Aken; Astrid De Vriese; Jeffrey I Weitz; Hartmut Weiler; Peter W Hellings; Paul Schaeffer; Jean-Marc Herbert; Désiré Collen; Gregor Theilmeier
The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways.
The Journal of experimental medicine 2002;196(5):565-77.
2002: Edward M Conway; Saskia Pollefeyt; Marta Steiner-Mosonyi; Wei Luo; Astrid Devriese; Florea Lupu; Françoise Bono; Nathalie Leducq; Frédérique Dol; Paul Schaeffer; Désiré Collen; Jean-Marc Herbert
Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways.
Gastroenterology 2002;123(2):619-31.
2001: Hartmut Weiler; V Lindner; Bryce A Kerlin; Berend Isermann; Sara B Hendrickson; Brian C Cooley; DA Meh; Michael W Mosesson; Nicholas W Shworak; M J Post; Edward M Conway; L H Ulfman; U H von Andrian; Jeffrey I Weitz
Characterization of a mouse model for thrombomodulin deficiency.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(9):1531-7.
2001: Edward M Conway; Désiré Collen; Peter Carmeliet
Molecular mechanisms of blood vessel growth.
Cardiovascular research 2001;49(3):507-21.
2000: K Ong; Wendy Horsfall; Edward M Conway; Andre C Schuh
Early embryonic expression of murine coagulation system components.
Thrombosis and haemostasis 2000;84(6):1023-30.
2000: Edward M Conway; Saskia Pollefeyt; J Cornelissen; I DeBaere; Marta Steiner-Mosonyi; K Ong; M Baens; Désiré Collen; Andre C Schuh
Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions.
Blood 2000;95(4):1435-42.
1999: Edward M Conway; Saskia Pollefeyt; J Cornelissen; I DeBaere; Marta Steiner-Mosonyi; Jeffrey I Weitz; H Weiler-Guettler; Peter Carmeliet; Désiré Collen
Structure-function analyses of thrombomodulin by gene-targeting in mice: the cytoplasmic domain is not required for normal fetal development.
Blood 1999;93(10):3442-50.
1999: S Rabhi-Sabile; Marta Steiner-Mosonyi; Saskia Pollefeyt; Désiré Collen; Bruno Pouvelle; Jurg Gysin; MC Boffa; Edward M Conway
Plasmodium falciparum-infected erythrocytes: a mutational analysis of cytoadherence via murine thrombomodulin.
Thrombosis and haemostasis 1999;81(5):815-21.
1997: Edward M Conway; Saskia Pollefeyt; Désiré Collen; Marta Steiner-Mosonyi
The amino terminal lectin-like domain of thrombomodulin is required for constitutive endocytosis.
Blood 1997;89(2):652-61.
1996: S Tharin; P A Hamel; Edward M Conway; Marek Michalak; Michal Opas
Regulation of calcium binding proteins calreticulin and calsequestrin during differentiation in the myogenic cell line L6.
Journal of cellular physiology 1996;166(3):547-60.
1995: Edward M Conway; L Liu; B Nowakowski; Marta Steiner-Mosonyi; S P Ribeiro; Marek Michalak
Heat shock-sensitive expression of calreticulin. In vitro and in vivo up-regulation.
The Journal of biological chemistry 1995;270(28):17011-6.
1994: Edward M Conway; L Liu; B Nowakowski; Marta Steiner-Mosonyi; Robert Jackman
Heat shock of vascular endothelial cells induces an up-regulatory transcriptional response of the thrombomodulin gene that is delayed in onset and does not attenuate.
The Journal of biological chemistry 1994;269(36):22804-10.
1994: Edward M Conway; B Nowakowski; Marta Steiner-Mosonyi
Thrombomodulin lacking the cytoplasmic domain efficiently internalizes thrombin via nonclathrin-coated, pit-mediated endocytosis.
Journal of cellular physiology 1994;158(2):285-98.
1993: Edward M Conway; B Nowakowski
Biologically active thrombomodulin is synthesized by adherent synovial fluid cells and is elevated in synovial fluid of patients with rheumatoid arthritis.
Blood 1993;81(3):726-33.
1992: Edward M Conway; B Nowakowski; Marta Steiner-Mosonyi
Human neutrophils synthesize thrombomodulin that does not promote thrombin-dependent protein C activation.
Blood 1992;80(5):1254-63.
1992: Edward M Conway; MC Boffa; B Nowakowski; Marta Steiner-Mosonyi
An ultrastructural study of thrombomodulin endocytosis: internalization occurs via clathrin-coated and non-coated pits.
Journal of cellular physiology 1992;151(3):604-12.