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James Cook

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Septic Shock

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TOP 3
Pengfei Li; Richard Neubig; Basilia Zingarelli; KT Borg; James A Cook; Perry V Halushka; Hongkuan Fan
Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein.
Hongkuan Fan; Perry V Halushka; Donald Wong; Sarah H Ashton; KT Borg; James A Cook
Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation.
Pengfei Li; Louis M Luttrell; Liping Wang; KT Borg; James A Cook; Gary S Gilkeson; Perry V Halushka; Hongkuan Fan
Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.

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2012: Pengfei Li; Richard Neubig; Basilia Zingarelli; KT Borg; James A Cook; Perry V Halushka; Hongkuan Fan
Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein.
Inflammation 2012;35(5):1611-7.
2012: Hongkuan Fan; Perry V Halushka; Donald Wong; Sarah H Ashton; KT Borg; James A Cook
Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation.
Inflammation 2012;35(1):130-7.
2011: Pengfei Li; Louis M Luttrell; Liping Wang; KT Borg; James A Cook; Gary S Gilkeson; Perry V Halushka; Hongkuan Fan
Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.
Molecular immunology 2011;49(1-2):64-74.
2011: Hongkuan Fan; Pengfei Li; Basilia Zingarelli; Keith Borg; Perry V Halushka; Lutz Birnbaumer; James A Cook
Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis.
Biochimica et biophysica acta 2011;1813(3):466-72.
2010: Basilia Zingarelli; Giovanna Piraino; Paul W Hake; Michael O'Connor; Alvin Denenberg; Hongkuan Fan; James A Cook
Peroxisome proliferator-activated receptor {delta} regulates inflammation via NF-{kappa}B signaling in polymicrobial sepsis.
The American journal of pathology 2010;177(4):1834-47.
2010: Hongkuan Fan; Alessandra Bitto; Basilia Zingarelli; Louis M Luttrell; KT Borg; Perry V Halushka; James A Cook
Beta-arrestin 2 negatively regulates sepsis-induced inflammation.
Immunology 2010;130(3):344-51.
2008: Derek S Wheeler; Patrick M Lahni; Alvin Denenberg; Sue E Poynter; Hector R Wong; James A Cook; Basilia Zingarelli
Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis.
Shock (Augusta, Ga.) 2008;30(3):267-73.
2008: Hongkuan Fan; Basilia Zingarelli; Vashaunta Harris; George E Tempel; Perry V Halushka; James A Cook
Lysophosphatidic acid inhibits bacterial endotoxin-induced pro-inflammatory response: potential anti-inflammatory signaling pathways.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):422-8.
2008: Basilia Zingarelli; Hongkuan Fan; Sarah Ashton; Giovanna Piraino; Prajakta Mangeshkar; James A Cook
Peroxisome proliferator activated receptor gamma is not necessary for the development of LPS-induced tolerance in macrophages.
Immunology 2008;124(1):51-7.
2008: Fahmin Basher; Hongkuan Fan; Basilia Zingarelli; KT Borg; Louis M Luttrell; George E Tempel; Perry V Halushka; James A Cook
beta-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes.
International journal of clinical and experimental medicine 2008;1(1):32-41.
2007: Jennifer Kaplan; James A Cook; Michael O'Connor; Basilia Zingarelli
Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells.
Shock (Augusta, Ga.) 2007;28(6):722-726.
2007: Hongkuan Fan; David L Williams; Basilia Zingarelli; Kevin F Breuel; Giuseppe Teti; George E Tempel; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; Perry V Halushka; James A Cook
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins.
Immunology 2007;122(1):116-23.
2007: Hongkuan Fan; Louis M Luttrell; George E Tempel; Joseph J Senn; Perry V Halushka; James A Cook
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.
Molecular immunology 2007;44(12):3092-9.
2006: Hongkuan Fan; David L Williams; Basilia Zingarelli; Kevin F Breuel; Giuseppe Teti; George E Tempel; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; Perry V Halushka; James A Cook
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins.
Biochimica et biophysica acta 2006;1763(10):1051-8.
2006: Giovanna Piraino; James A Cook; Michael O'Connor; Paul W Hake; Timothy J Burroughs; Diana Teti; Basilia Zingarelli
Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages.
Shock (Augusta, Ga.) 2006;26(2):146-53.
2006: Octavia M Peck; Basilia Zingarelli; Hongkuan Fan; Giuseppe Teti; George E Tempel; Perry V Halushka; James A Cook
The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide.
Shock (Augusta, Ga.) 2006;26(1):31-6.
2006: Hongkuan Fan; David L Williams; Kevin F Breuel; Basilia Zingarelli; Giuseppe Teti; George E Tempel; Perry V Halushka; James A Cook
Gi proteins regulate lipopolysaccharide and Staphylococcus aureus induced cytokine production but not (1--> 3)-beta-D-glucan induced cytokine suppression.
Frontiers in bioscience : a journal and virtual library 2006;11():2264-74.
2005: James A Cook
Eicosanoids.
Critical care medicine 2005;33(12 Suppl):S488-91.
2005: Hongkuan Fan; Basilia Zingarelli; Octavia M Peck; Giuseppe Teti; George E Tempel; Perry V Halushka; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; James A Cook
Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins.
American journal of physiology. Cell physiology 2005;289(2):C293-301.
2005: Jennifer M Kaplan; James A Cook; Paul W Hake; Michael O'Connor; Timothy J Burroughs; Basilia Zingarelli
15-Deoxy-delta(12,14)-prostaglandin J(2) (15D-PGJ(2)), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock.
Shock (Augusta, Ga.) 2005;24(1):59-65.
2005: Basilia Zingarelli; James A Cook
Peroxisome proliferator-activated receptor-gamma is a new therapeutic target in sepsis and inflammation.
Shock (Augusta, Ga.) 2005;23(5):393-9.
2004: Hongkuan Fan; Octavia M Peck; George E Tempel; Perry V Halushka; James A Cook
Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
Shock (Augusta, Ga.) 2004;22(1):57-62.
2004: Octavia M Peck; David L Williams; Kevin F Breuel; John H Kalbfleisch; Hongkuan Fan; George E Tempel; Giuseppe Teti; James A Cook
Differential regulation of cytokine and chemokine production in lipopolysaccharide-induced tolerance and priming.
Cytokine 2004;26(5):202-8.
2004: Octavia M Peck; Hongkuan Fan; George E Tempel; Giuseppe Teti; Perry V Halushka; James A Cook
Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma.
Shock (Augusta, Ga.) 2004;21(3):254-60.
2004: Hongkuan Fan; James A Cook
Molecular mechanisms of endotoxin tolerance.
Journal of endotoxin research 2004;10(2):71-84.
2003: Basilia Zingarelli; Maeve Sheehan; Paul W Hake; Michael O'Connor; Alvin Denenberg; James A Cook
Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6827-37.
2003: Kelly Guyton; Basilia Zingarelli; Sarah Ashton; Giuseppe Teti; George E Tempel; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli.
Shock (Augusta, Ga.) 2003;20(1):56-62.
2003: Hongkuan Fan; Giuseppe Teti; Sarah Ashton; Kelly Guyton; George E Tempel; Perry V Halushka; James A Cook
Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus.
Cytokine 2003;22(5):126-33.
2002: Giuseppe Mancuso; Angelina Midiri; Concetta Beninati; Giovanna Piraino; Andrea Valenti; Giacomo Nicocia; Diana Teti; James A Cook; Giuseppe Teti
Mitogen-activated protein kinases and NF-kappa B are involved in TNF-alpha responses to group B streptococci.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1401-9.
2002: Basilia Zingarelli; Paul W Hake; James A Cook
Inducible nitric oxide synthase is not required in the development of endotoxin tolerance in mice.
Shock (Augusta, Ga.) 2002;17(6):478-84.
2002: Marcella Ferlito; Olga G Romanenko; Kelly Guyton; Sarah Ashton; Francesco Squadrito; Perry V Halushka; James A Cook
Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production.
Journal of endotoxin research 2002;8(6):427-35.
2001: George E Tempel; Alan N Brown; Thomas A Morinelli; Perry V Halushka; James A Cook
Changes in vascular responsiveness to a thromboxane mimetic in endotoxin tolerance.
Shock (Augusta, Ga.) 2001;16(5):389-92.
2001: Marcella Ferlito; O G Romanenko; Sarah Ashton; Francesco Squadrito; Perry V Halushka; James A Cook
Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production.
Journal of leukocyte biology 2001;70(5):821-9.
2001: Kelly Guyton; R Bond; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal of leukocyte biology 2001;69(4):631-8.
2001: Marcella Ferlito; Francesco Squadrito; Perry V Halushka; James A Cook
Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization.
Shock (Augusta, Ga.) 2001;15(4):291-6.
2000: Lawrence P Fernando; Anthony N Fernando; Marcella Ferlito; Perry V Halushka; James A Cook
Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid.
Shock (Augusta, Ga.) 2000;14(2):128-33.
2000: Christopher M Reilly; Jim Oates; James A Cook; J D Morrow; Perry V Halushka; Gary S Gilkeson
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1498-504.
1999: Joel B Cochran; F Genovese; S Ogura; Giuseppe Teti; James A Cook
Effect of nitric oxide donors and nitric oxide synthase inhibitors in neonatal rat endotoxic shock.
Biochemical pharmacology 1999;58(4):687-91.
1999: S Ogura; O Umegaki; F Genovese; L P Fernando; Joel B Cochran; C M Romeo; James A Cook
Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria.
Shock (Augusta, Ga.) 1999;12(2):105-10.
1999: Lawrence P Fernando; MA Makhlouf; Anthony N Fernando; Sarah Ashton; Perry V Halushka; James A Cook
Tolerance to LPS decreases macrophage G protein content.
Shock (Augusta, Ga.) 1999;11(5):330-5.
1999: Joel B Cochran; F Genovese; C Romeo; Kelly Guyton; Giuseppe Teti; James A Cook
The effect of a tyrosine kinase inhibitor on endotoxin mortality and splenocyte mediator production in the neonatal rat.
Shock (Augusta, Ga.) 1999;11(1):35-8.
1998: M M Durando; K E Meier; James A Cook
Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization.
Journal of leukocyte biology 1998;64(2):259-64.
1998: James A Cook
Molecular basis of endotoxin tolerance.
Annals of the New York Academy of Sciences 1998;851():426-8.
1998: M Durando; Lawrence P Fernando; Sarah Ashton; Perry V Halushka; James A Cook
Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity.
Shock (Augusta, Ga.) 1998;9(5):359-63.
1998: MA Makhlouf; Lawrence P Fernando; Thomas W Gettys; Perry V Halushka; James A Cook
Increased prostacyclin and PGE2 stimulated cAMP production by macrophages from endotoxin-tolerant rats.
The American journal of physiology 1998;274(5 Pt 1):C1238-44.
1998: MA Makhlouf; B Zingarelli; Perry V Halushka; James A Cook
Endotoxin tolerance alters macrophage membrane regulatory G proteins.
Progress in clinical and biological research 1998;397():217-26.
1997: Valentina Valeria Cusumano; Giuseppe Mancuso; F Genovese; M Cuzzola; Maria Carbone; James A Cook; Joel B Cochran; Giuseppe Teti
Neonatal hypersusceptibility to endotoxin correlates with increased tumor necrosis factor production in mice.
The Journal of infectious diseases 1997;176(1):168-76.
1997: Mayuki Aibiki; James A Cook
Ulinastatin, a human trypsin inhibitor, inhibits endotoxin-induced thromboxane B2 production in human monocytes.
Critical care medicine 1997;25(3):430-4.
1996: M Makhlouf; Sarah Ashton; John D Hildebrandt; N Mehta; Thomas W Gettys; Perry V Halushka; James A Cook
Alterations in macrophage G proteins are associated with endotoxin tolerance.
Biochimica et biophysica acta 1996;1312(2):163-8.
1996: B S Pender; H Chen; Sarah Ashton; W C Wise; B Zingarelli; Valentina Valeria Cusumano; James A Cook
Transforming growth factor beta 1 alters rat peritoneal macrophage mediator production and improves survival during endotoxic shock.
European cytokine network 1996;7(2):137-42.
1996: R S Wagner; Perry V Halushka; James A Cook
Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells.
Shock (Augusta, Ga.) 1996;5(1):41-6.
1995: Joel B Cochran; H Chen; M La Via; Valentina Valeria Cusumano; Giuseppe Teti; James A Cook
Age-related mortality and adherent splenic cell mediator production to endotoxin in the rat.
Shock (Augusta, Ga.) 1995;4(6):450-4.
1995: B Zingarelli; Perry V Halushka; A P Caputi; James A Cook
Increased nitric oxide synthesis during the development of endotoxin tolerance.
Shock (Augusta, Ga.) 1995;3(2):102-8.
1995: L Bertók; A Takáts; H Chen; James A Cook
Radiodetoxified endotoxin-induced tolerance. Effect on endotoxin lethality and macrophage arachidonic acid metabolism.
Acta microbiologica et immunologica Hungarica 1995;42(4):409-18.
1995: B Zingarelli; H Chen; A P Caputi; Perry V Halushka; James A Cook
Reorientation of macrophage mediator production in endotoxin tolerance.
Progress in clinical and biological research 1995;392():529-37.
1994: Giuseppe Mancuso; Francesco Tomasello; M Migliardo; Demetrio Delfino; Joel B Cochran; James A Cook; Giuseppe Teti
Beneficial effects of interleukin-6 in neonatal mouse models of group B streptococcal disease.
Infection and immunity 1994;62(11):4997-5002.
1994: J Geisel; James A Cook; Sarah Ashton; W C Wise; Perry V Halushka
Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2.
The American journal of physiology 1994;267(4 Pt 1):C1067-72.
1994: Giuseppe Mancuso; Valentina Valeria Cusumano; James A Cook; E Smith; F Squadrito; G Blandino; Giuseppe Teti
Efficacy of tumor necrosis factor alpha and eicosanoid inhibitors in experimental models of neonatal sepsis.
FEMS immunology and medical microbiology 1994;9(1):49-54.
1994: H Chen; Perry V Halushka; James A Cook
Endotoxin tolerance: effects on lethality and macrophage thromboxane (B2) and interleukin 6 production.
Shock (Augusta, Ga.) 1994;1(5):366-71.
1993: Giovanni Matera; James A Cook; J Geisel; Sarah Ashton; W C Wise; A Focá; B A Berkowitz; Perry V Halushka
Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages.
Antimicrobial agents and chemotherapy 1993;37(3):393-7.
1993: T R Simmons; James A Cook; James N Moore; Perry V Halushka
Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors.
Journal of leukocyte biology 1993;53(2):173-8.
1993: James A Cook; J Geisel; Perry V Halushka; H D Reines
Prostaglandins, thromboxanes, leukotrienes, and cytochrome P-450 metabolites of arachidonic acid.
New horizons (Baltimore, Md.) 1993;1(1):60-9.
1992: K A Coffee; Perry V Halushka; Sarah Ashton; George E Tempel; W C Wise; James A Cook
Endotoxin tolerance is associated with altered GTP-binding protein function.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(3):1008-13.
1991: J Geisel; James A Cook; K A Coffee; W C Wise; Perry V Halushka
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Biochimica et biophysica acta 1991;1085(1):15-20.
1991: E J Li; James A Cook; W C Wise; W T Jackson; Perry V Halushka
Effect of LTB4 receptor antagonists in endotoxic shock in the rat.
Circulatory shock 1991;34(4):385-92.
1991: E J Li; James A Cook; Sarah Ashton; W C Wise; Perry V Halushka
Effect of the LTD4 receptor antagonist LY203647 on endotoxic shock sequelae in the rat.
European journal of pharmacology 1991;199(2):221-5.
1991: James N Moore; James A Cook; M M Henry; H T Jonsson; Kenneth M. Spicer; W C Wise; Perry V Halushka
Effects of a linseed oil enriched diet on endotoxin-induced sequelae: differential in vitro and in vivo effects.
Eicosanoids 1991;4(1):47-55.
1991: James L Zellner; Francis G Spinale; Fred A Crawford; James A Cook
Right ventricular pump dysfunction with acute experimental septic shock.
The Journal of surgical research 1991;50(1):93-9.
1991: K A Coffee; Perry V Halushka; W C Wise; George E Tempel; James A Cook
Endotoxin tolerance differentially alters hemodynamic responses to a thromboxane A2 mimetic and phenylephrine.
Journal of cardiovascular pharmacology 1991;17(1):20-6.
1991: James L Zellner; James A Cook; H D Reines; E F Smith; L D Kessler; Perry V Halushka
Effect of a LTD4 receptor antagonist in porcine septic shock.
Eicosanoids 1991;4(3):169-75.
1990: James A Cook; E J Li; Kenneth M. Spicer; W C Wise; Perry V Halushka
Effect of leukotriene receptor antagonists on vascular permeability during endotoxic shock.
Circulatory shock 1990;32(3):209-18.
1990: K A Coffee; Perry V Halushka; W C Wise; James A Cook
Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance.
Biochimica et biophysica acta 1990;1035(2):201-5.
1990: James N Moore; James A Cook; D D Morris; Perry V Halushka; W C Wise
Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.
Circulatory shock 1990;31(3):281-95.
1990: E J Li; James A Cook; Kenneth M. Spicer; W C Wise; J Rokach; Perry V Halushka
Resistance of essential fatty acid-deficient rats to endotoxin-induced increases in vascular permeability.
Circulatory shock 1990;31(2):159-70.
1990: James L Zellner; James A Cook; D H Reines; W C Wise; E F Smith; L D Kessler; Perry V Halushka
Hemodynamic effects of leukotriene (LT) D4 and a LTD4 receptor antagonist in the pig.
Eicosanoids 1990;3(4):219-24.
1989: John Heffner; James A Cook; Perry V Halushka
Human platelets modulate edema formation in isolated rabbit lungs.
The Journal of clinical investigation 1989;84(3):757-64.
1989: H A Ball; James A Cook; Kenneth M. Spicer; W C Wise; Perry V Halushka
Essential fatty acid-deficient rats are resistant to oleic acid-induced pulmonary injury.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):811-6.
1989: G H Watt; Sarah Ashton; James A Cook; W C Wise; Perry V Halushka; R M Galbraith
Alterations in plasma levels and complexing of Gc (vitamin D-binding protein) in rats with endotoxic shock.
Circulatory shock 1989;28(3):279-91.
1989: William M Lee; D Reines; G H Watt; James A Cook; W C Wise; Perry V Halushka; R M Galbraith
Alterations in Gc levels and complexing in septic shock.
Circulatory shock 1989;28(3):249-55.
1989: T S Rogers; Perry V Halushka; W C Wise; James A Cook
Arachidonic acid turnover in peritoneal macrophages is altered in endotoxin-tolerant rats.
Biochimica et biophysica acta 1989;1001(2):169-75.
1989: W C Wise; James A Cook; George E Tempel; H D Reines; Perry V Halushka
The rat in sepsis and endotoxic shock.
Progress in clinical and biological research 1989;299():243-52.
1989: George E Tempel; J W Strong; W C Wise; James A Cook; E F Smith; Perry V Halushka
The role of eicosanoids in mediating blood flow alterations in endotoxin shock.
Progress in clinical and biological research 1989;299():33-42.
1988: Giovanni Matera; James A Cook; Randolph A Hennigar; George E Tempel; W C Wise; T D Oglesby; Perry V Halushka
Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1988;247(1):363-71.
1988: S A Katz; M Venkatachalam; R K Crouch; John Heffner; Perry V Halushka; W C Wise; James A Cook
Catalase pretreatment attenuates oleic acid-induced edema in isolated rabbit lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1301-6.
1988: John Heffner; S A Katz; Perry V Halushka; James A Cook
Human platelets attenuate oxidant injury in isolated rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1258-66.
1988: H A Ball; James A Cook; Kenneth M. Spicer; C Y Hsu; Perry V Halushka
Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes.
Circulatory shock 1988;26(1):59-70.
1988: Giovanni Matera; M Chisari; D Altavilla; A Foca; James A Cook
Selective thromboxane synthetase inhibition by picotamide and effects on endotoxin-induced lethality.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1988;187(1):58-61.
1988: Domenica Altavilla; M C Berlinghieri; Alfredo Focà; James A Cook
Effect of bacterial endotoxin on lipoxygenase and cyclo-oxygenase metabolites by rat neutrophils and correlation with cellular functional parameters.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1988;188(1):9-17.
1987: E F Smith; W C Wise; Perry V Halushka; James A Cook
Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.
Biochimica et biophysica acta 1987;923(3):355-61.
1987: S A Katz; Perry V Halushka; W C Wise; James A Cook
Oleic acid induces pulmonary injury independent of eicosanoids in the isolated, perfused rabbit lung.
Circulatory shock 1987;22(3):221-30.
1987: A R Etemadi; George E Tempel; B A Farah; W C Wise; Perry V Halushka; James A Cook
Beneficial effects of a leukotriene antagonist on endotoxin-induced acute hemodynamic alterations.
Circulatory shock 1987;22(1):55-63.
1986: George E Tempel; James A Cook; W C Wise; Perry V Halushka; D Corral
Improvement in organ blood flow by inhibition of thromboxane synthetase during experimental endotoxic shock in the rat.
Journal of cardiovascular pharmacology 1986;8(3):514-9.
1986: T S Rogers; Perry V Halushka; W C Wise; James A Cook
Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.
Prostaglandins 1986;31(4):639-50.
1986: J Armstrong; George E Tempel; James A Cook; W C Wise; Perry V Halushka
The effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia.
Circulatory shock 1986;20(2):151-9.
1986: H A Ball; James A Cook; W C Wise; Perry V Halushka
Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock.
Intensive care medicine 1986;12(3):116-26.
1985: James A Cook; W C Wise; Perry V Halushka
Protective effect of a selective leukotriene antagonist in endotoxemia in the rat.
The Journal of pharmacology and experimental therapeutics 1985;235(2):470-4.
1985: L S Olanoff; James A Cook; Perry V Halushka
Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.
Prostaglandins 1985;29(6):1031-7.
1985: Perry V Halushka; H D Reines; S E Barrow; Ian Blair; C T Dollery; W Rambo; James A Cook; W C Wise
Elevated plasma 6-keto-prostaglandin F1 alpha in patients in septic shock.
Critical care medicine 1985;13(6):451-3.
1985: H D Reines; Perry V Halushka; James A Cook; C B Loadholt
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock.
Surgery, gynecology & obstetrics 1985;160(4):320-2.
1985: James A Cook; W C Wise; George E Tempel; Perry V Halushka
Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia.
Circulatory shock 1985;15(3):193-204.
1985: W C Wise; Perry V Halushka; Rebecca G Knapp; James A Cook
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
Circulatory shock 1985;17(1):59-71.
1985: L S Olanoff; James A Cook; T Eller; Daniel R Knapp; Perry V Halushka
Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia.
Journal of cardiovascular pharmacology 1985;7(1):114-20.
1985: E F Smith; George E Tempel; W C Wise; Perry V Halushka; James A Cook
Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.
Circulatory shock 1985;16(1):1-7.
1984: T S Rogers; E F Smith; W C Wise; Perry V Halushka; James A Cook
Interaction of eicosanoids and macrophages during inflammatory responses.
Survey of immunologic research 1984;3(2-3):161-4.
1984: James A Cook; W C Wise; R R Butler; H D Reines; W Rambo; Perry V Halushka
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
The American journal of emergency medicine 1984;2(1):28-37.
1983: Perry V Halushka; W C Wise; James A Cook
Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism.
The American journal of medicine 1983;74(6A):91-6.
1983: K Anderegg; P Anzeveno; James A Cook; Perry V Halushka; J McCarthy; E Wagner; W C Wise
Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat.
British journal of pharmacology 1983;78(4):725-32.
1983: R R Butler; W C Wise; Perry V Halushka; James A Cook
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
The Journal of pharmacology and experimental therapeutics 1983;225(1):94-101.
1983: W C Wise; James A Cook; Perry V Halushka
Arachidonic acid metabolism in endotoxin tolerance.
Advances in shock research 1983;10():131-42.
1983: Perry V Halushka; James A Cook; W C Wise
Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.
British journal of clinical pharmacology 1983;15 Suppl 1():133S-139S.
1982: H D Reines; Perry V Halushka; James A Cook; W C Wise; W Rambo
Plasma thromboxane concentrations are raised in patients dying with septic shock.
Lancet 1982;2(8291):174-5.
1982: James A Cook; Perry V Halushka; W C Wise
Modulation of macrophage arachidonic acid metabolism: potential role in the susceptibility of rats to endotoxic shock.
Circulatory shock 1982;9(6):605-17.
1982: George E Tempel; James A Cook; W C Wise; Perry V Halushka
The improvement in endotoxin-induced redistribution of organ blood flow by inhibition of thromboxane and prostaglandin synthesis.
Advances in shock research 1982;7():209-18.
1982: R R Butler; W C Wise; Perry V Halushka; James A Cook
Thromboxane and prostacyclin production during septic shock.
Advances in shock research 1982;7():133-45.
1981: James A Cook; W C Wise; Perry V Halushka
Thromboxane A2 and prostacyclin production by lipopolysaccharide-stimulated peritoneal macrophages.
Journal of the Reticuloendothelial Society 1981;30(5):445-50.
1981: Perry V Halushka; W C Wise; James A Cook
Protective effects of aspirin in endotoxic shock.
The Journal of pharmacology and experimental therapeutics 1981;218(2):464-9.
1981: James A Cook; W J Dougherty; T Holt
Distribution of 203Pb during lead-potentiated endotoxic shock.
Experimental and molecular pathology 1981;34(3):253-63.
1981: James A Cook; W C Wise; Daniel R Knapp; Perry V Halushka
Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2.
Circulatory shock 1981;8(1):69-76.
1981: W C Wise; James A Cook; Perry V Halushka
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.
Advances in shock research 1981;6():83-91.
1981: James A Cook; W C Wise; Daniel R Knapp; Perry V Halushka
Essential fatty acid deficient rats: a new model for evaluating arachidonate metabolism in shock.
Advances in shock research 1981;6():93-105.
1980: W C Wise; James A Cook; T Eller; Perry V Halushka
Ibuprofen improves survival from endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1980;215(1):160-4.
1980: W C Wise; James A Cook; Perry V Halushka; Daniel R Knapp
Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock.
Circulation research 1980;46(6):854-9.
1980: James A Cook; W C Wise; Perry V Halushka
Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency.
The Journal of clinical investigation 1980;65(1):227-30.
1980: James A Cook; W J Dougherty; T M Holt
Enhanced sensitivity to endotoxin induced by the RE stimulant, glucan.
Circulatory shock 1980;7(3):225-38.