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Alexander Cools
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56
Ellenbroek, Bart
16
Veening, Jan
16
Berger, Hans
15
van Spaendonck, Karel
15
Horstink, Martin
9
Andringa, Gerda
8
Olivier, Berend
8
Verheij, M M M
7
Waldinger, Marcel
7
de Bruin, Natasja
7
van Luijtelaar, E L J M
7
de Jong, Trynke
6
Arts, MP
6
Pattij, Tommy
6
van der Elst, Martine
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All Publications
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2009: Olivier J D A; Jans L A W; Blokland A; Broers N J; Homberg J R; Ellenbroek B A; Cools A R
Serotonin transporter deficiency in rats contributes to impaired object memory.
Genes, brain, and behavior 2009;8(8):829-34.
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2009: Verheij M M M; Cools A R
Mesolimbic alpha-, but not beta-adrenoceptors control the accumbal release of dopamine that is derived from reserpine-sensitive storage vesicles.
Neuroscience 2009;162(4):1163-73.
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2009: Verheij Michel M M; Veenvliet Jesse V; Groot Kormelink Tom; Steenhof Maaike; Cools Alexander R
Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty.
Psychopharmacology 2009;205(3):441-55.
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2009: Verheij M M M; Cools A R
Accumbal noradrenaline that contributes to the alpha-adrenoceptor-mediated release of dopamine from reserpine-sensitive storage vesicles in the nucleus accumbens is derived from alpha-methyl-para-tyrosine-sensitive pools.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(4):389-94.
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2008: Olivier J D A; Jans L A W; Korte-Bouws G A H; Korte S M; Deen P M T; Cools A R; Ellenbroek B A; Blokland A
Acute tryptophan depletion dose dependently impairs object memory in serotonin transporter knockout rats.
Psychopharmacology 2008;200(2):243-54.
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2008: de Rover Mischa; Petersson Karl Magnus; van der Werf Sieberen P; Cools Alexander R; Berger Hans J; Fernández Guillén
Neural correlates of strategic memory retrieval: differentiating between spatial-associative and temporal-associative strategies.
Human brain mapping 2008;29(9):1068-79.
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2008: Olivier Jocelien D A; Cools Alexander R; Olivier Berend; Homberg Judith R; Cuppen Edwin; Ellenbroek Bart A
Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats.
European journal of pharmacology 2008;590(1-3):190-7.
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2008: Verheij Michel M M; Cools Alexander R
Twenty years of dopamine research: individual differences in the response of accumbal dopamine to environmental and pharmacological challenges.
European journal of pharmacology 2008;585(2-3):228-44.
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2008: Olivier J D A; Van Der Hart M G C; Van Swelm R P L; Dederen P J; Homberg J R; Cremers T; Deen P M T; Cuppen E; Cools A R; Ellenbroek B A
A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders.
Neuroscience 2008;152(3):573-84.
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2007: Olivier Jocelien D A; de Jong Trynke R; Jos Dederen P; van Oorschot Ruud; Heeren Dick; Pattij Tommy; Waldinger Marcel D; Coolen Lique M; Cools Alexander R; Olivier Berend; Veening Jan G
Effects of acute and chronic apomorphine on sex behavior and copulation-induced neural activation in the male rat.
European journal of pharmacology 2007;576(1-3):61-76.
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2007: Berger Hans J; van der Werf Sieberen P; Horstink Casper A; Cools Alexander R; Oyen Wim J; Horstink Martin W
Writer's cramp: restoration of striatal D2-binding after successful biofeedback-based sensorimotor training.
Parkinsonism & related disorders 2007;13(3):170-3.
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2007: Verheij M M M; Cools A R
Differential contribution of storage pools to the extracellular amount of accumbal dopamine in high and low responders to novelty: effects of reserpine.
Journal of neurochemistry 2007;100(3):810-21.
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2007: van der Elst Martine C J; Wunderink Yvette S; Ellenbroek Bart A; Cools Alexander R
Differences in the cellular mechanism underlying the effects of amphetamine on prepulse inhibition in apomorphine-susceptible and apomorphine-unsusceptible rats.
Psychopharmacology 2007;190(1):93-102.
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2006: van der Elst Martine C J; Ellenbroek Bart A; Cools Alexander R
Cocaine strongly reduces prepulse inhibition in apomorphine-susceptible rats, but not in apomorphine-unsusceptible rats: regulation by dopamine D2 receptors.
Behavioural brain research 2006;175(2):392-8.
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2006: Coolen M W; van Loo K M J; Ellenbroek B A; Cools A R; Martens G J M
Ontogenic reduction of Aph-1b mRNA and gamma-secretase activity in rats with a complex neurodevelopmental phenotype.
Molecular psychiatry 2006;11(8):787-93.
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2006: van der Kam Elizabeth L; Coolen Erik J C M; Ellenbroek Bart A; Cools Alexander R
Expression of cocaine-induced conditioned place preference in apomorphine susceptible and unsusceptible rats.
Behavioural pharmacology 2006;17(4):331-40.
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2006: De Leonibus Elvira; Verheij Michel M M; Mele Andrea; Cools Alexander
Distinct kinds of novelty processing differentially increase extracellular dopamine in different brain regions.
The European journal of neuroscience 2006;23(5):1332-40.
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2006: Coolen Marcel W; van Loo Karen M J; van Bakel Nick N H M; Ellenbroek Bart A; Cools Alexander R; Martens Gerard J M
Reduced Aph-1b expression causes tissue- and substrate-specific changes in gamma-secretase activity in rats with a complex phenotype.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):175-7.
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2006: de Jong Trynke R; Snaphaan Liselore J A E; Pattij Tommy; Veening Jan G; Waldinger Marcel D; Cools Alexander R; Olivier Berend
Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2006;16(1):39-48.
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2006: de Jong Trynke R; Veening Jan G; Waldinger Marcel D; Cools Alexander R; Olivier Berend
Serotonin and the neurobiology of the ejaculatory threshold.
Neuroscience and biobehavioral reviews 2006;30(7):893-907.
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2005: Ellenbroek Bart A; van der Kam Elizabeth L; van der Elst Martine C J; Cools Alexander R
Individual differences in drug dependence in rats: the role of genetic factors and life events.
European journal of pharmacology 2005;526(1-3):251-8.
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2005: Pattij Tommy; de Jong Trynke R; Uitterdijk Andre; Waldinger Marcel D; Veening Jan G; Cools Alexander R; van der Graaf Piet Hein; Olivier Berend
Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders.
The European journal of neuroscience 2005;22(3):724-34.
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2005: de Jong Trynke R; Pattij Tommy; Veening Jan G; Waldinger Marcel D; Cools Alexander R; Olivier Berend
Effects of chronic selective serotonin reuptake inhibitors on 8-OH-DPAT-induced facilitation of ejaculation in rats: comparison of fluvoxamine and paroxetine.
Psychopharmacology 2005;179(2):509-15.
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2005: van der Kam Elizabeth L; Ellenbroek Bart A; Cools Alexander R
Gene - environment interactions determine the individual variability in cocaine self-administration.
Neuropharmacology 2005;48(5):685-95.
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2005: Coolen Marcel W; Van Loo Karen M J; Van Bakel Nick N H M; Pulford David J; Serneels Lutgarde; De Strooper Bart; Ellenbroek Bart A; Cools Alexander R; Martens Gerard J M
Gene dosage effect on gamma-secretase component Aph-1b in a rat model for neurodevelopmental disorders.
Neuron 2005;45(4):497-503.
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2005: de Jong Trynke R; Pattij Tommy; Veening Jan G; Dederen P Jos W C; Waldinger Marcel D; Cools Alexander R; Olivier Berend
Citalopram combined with WAY 100635 inhibits ejaculation and ejaculation-related Fos immunoreactivity.
European journal of pharmacology 2005;509(1):49-59.
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2005: van der Kam E L; Coolen J C M; Ellenbroek B A; Cools A R
The effects of stress on alcohol consumption: mild acute and sub-chronic stressors differentially affect apomorphine susceptible and unsusceptible rats.
Life sciences 2005;76(15):1759-70.
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2005: van der Elst Martine C J; Verheij Michel M M; Roubos Eric W; Ellenbroek Bart A; Veening Jan G; Cools Alexander R
A single exposure to novelty differentially affects the accumbal dopaminergic system of apomorphine-susceptible and apomorphine-unsusceptible rats.
Life sciences 2005;76(12):1391-406.
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2005: Degen S B; Ellenbroek B A; Wiegant V M; Cools A R
The development of various somatic markers is retarded in an animal model for schizophrenia, namely apomorphine-susceptible rats.
Behavioural brain research 2005;157(2):369-77.
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2005: Keijsers N L W; Admiraal M A; Cools A R; Bloem B R; Gielen C C A M
Differential progression of proprioceptive and visual information processing deficits in Parkinson's disease.
The European journal of neuroscience 2005;21(1):239-48.
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2005: van Oosten R V; Verheij M M M; Cools A R
Bilateral nigral 6-hydroxydopamine lesions increase the amount of extracellular dopamine in the nucleus accumbens.
Experimental neurology 2005;191(1):24-32.
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2005: van der Elst Martine C J; Roubos Eric W; Ellenbroek Bart A; Veening Jan G; Cools Alexander R
Apomorphine-susceptible rats and apomorphine-unsusceptible rats differ in the tyrosine hydroxylase-immunoreactive network in the nucleus accumbens core and shell.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2005;160(4):418-23.
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2005: de Jong T R; Pattij T; Veening J G; Dederen P J W C; Waldinger M D; Cools A R; Olivier B
Effects of chronic paroxetine pretreatment on (+/-)-8-hydroxy-2-(di-n-propyl-amino)tetralin induced c-fos expression following sexual behavior.
Neuroscience 2005;134(4):1351-61.
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2004: Degen S B; Verheij M M M; Cools A R
Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype. A study with apomorphine-(un)susceptible Wistar rats.
Behavioural brain research 2004;154(1):107-12.
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2004: Teunis Marc A T; Heijnen Cobi J; Cools Alexander R; Kavelaars Annemieke
Reduced splenic natural killer cell activity in rats with a hyperreactive dopaminergic system.
Psychoneuroendocrinology 2004;29(8):1058-64.
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2004: Ellenbroek Bart A; de Bruin Natasja M W J; van Den Kroonenburg Peter T J M; van Luijtelaar Egidius L J M; Cools Alexander R
The effects of early maternal deprivation on auditory information processing in adult Wistar rats.
Biological psychiatry 2004;55(7):701-7.
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2004: Streijger Femke; Jost Carolina R; Oerlemans Frank; Ellenbroek Bart A; Cools Alexander R; Wieringa Bé; Van der Zee Catharina E E M
Mice lacking the UbCKmit isoform of creatine kinase reveal slower spatial learning acquisition, diminished exploration and habituation, and reduced acoustic startle reflex responses.
Molecular and cellular biochemistry 2004;256-257(1-2):305-18.
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2004: Kolk S M; Groffen A J A; Tuinhof R; Ouwens D T W M; Cools A R; Jenks B G; Verhage M; Roubos E W
Differential distribution and regulation of expression of synaptosomal-associated protein of 25 kDa isoforms in the Xenopus pituitary gland and brain.
Neuroscience 2004;128(3):531-43.
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2004: Berger Hans J C; Cools Alexander R; Horstink Martin W I M; Oyen Wim J G; Verhoeven Elisabeth W M; van der Werf Sieberen P
Striatal dopamine and learning strategy-an (123)I-FP-CIT SPECT study.
Neuropsychologia 2004;42(8):1071-8.
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2003: Andringa Gerda; Eshuis Silvia; Perentes Elias; Maguire R Paul; Roth Daniel; Ibrahim Merdol; Leenders Klaus L; Cools Alexander R
TCH346 prevents motor symptoms and loss of striatal FDOPA uptake in bilaterally MPTP-treated primates.
Neurobiology of disease 2003;14(2):205-17.
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2003: Roubos E W; Spooren W P J M; Martens G J M; Veening J G; Cools A R
NPY-mRNA expressions in the nucleus accumbens, caudate putamen and cerebral cortex of apomorphine-susceptible and apomorphine-unsusceptible rats.
Cell and tissue research 2003;313(2):209-15.
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2003: Berger Hans J C; Aerts Francisca H T M; van Spaendonck Karel P M; Cools Alexander R; Teunisse Jan-Pieter
Central coherence and cognitive shifting in relation to social improvement in high-functioning young adults with autism.
Journal of clinical and experimental neuropsychology 2003;25(4):502-11.
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2003: Sontag T A; Cools A R; Ellenbroek B A
Removal of short-term isolation stress differentially influences prepulse inhibition in APO-SUS and APO-UNSUS rats.
Behavioural brain research 2003;141(2):171-5.
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2003: Riksen Niels P; Ellenbroek Bart; Cools Alexander R; Siero Helene; Rongen Gerard A; Smits Bart W; Russel Frans G M; Smits Paul
Stress susceptibility as a determinant of endothelium-dependent vascular reactivity in rat mesenteric arteries.
Journal of cardiovascular pharmacology 2003;41(4):625-31.
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2003: Degen S B; Geven E J W; Sluyter F; Hof M W P; van der Elst M C J; Cools A R
Apomorphine-susceptible and apomorphine-unsusceptible Wistar rats differ in their recovery from stress-induced ulcers.
Life sciences 2003;72(10):1117-24.
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2003: van den Bos R; Cools A R
Switching to cue-directed behavior: specific for ventral striatal dopamine but not ventral pallidum/substantia innominata gaba as revealed by a swimming-test procedure in rats.
Neuroscience 2003;118(4):1141-9.
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2002: Tuinstra T; Cobelens P; Lubbers L; Verheij M; Cools A R
High and low responders to novelty and mesolimbic noradrenaline: effects of noradrenergic agents on radial-maze performance.
Behavioral neuroscience 2002;116(6):1084-92.
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2002: Teunis Marc A T; Heijnen Cobi J; Sluyter Frans; Bakker Joost M; Van Dam Anne-Marie M W; Hof Maleen; Cools Alexander R; Kavelaars Annemieke
Maternal deprivation of rat pups increases clinical symptoms of experimental autoimmune encephalomyelitis at adult age.
Journal of neuroimmunology 2002;133(1-2):30-8.
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2002: Smits Bart W; Siero Helene L M; Ellenbroek Bart A; Riksen Niels P; Cools Alexander R; Borggreven Joop M P M; Rongen Gerard A; Russel Frans G M; Smits Paul
Stress susceptibility as a determinant of the response to adrenergic stimuli in mesenteric resistance arteries of the rat.
Journal of cardiovascular pharmacology 2002;40(5):678-83.
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2002: Breivik T; Thrane P S; Gjermo P; Cools A; Myhrer T
Effects of hippocampal lesioning on experimental periodontitis in Wistar rats.
Journal of periodontal research 2002;37(5):360-5.
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2002: Lanser Marja G; Berger Hans J C; Ellenbroek Bart A; Cools Alexander R; Zitman Frans G
Perseveration in schizophrenia: failure to generate a plan and relationship with the psychomotor poverty subsyndrome.
Psychiatry research 2002;112(1):13-26.
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2002: Teunis Marc A T; Kavelaars Annemieke; Voest Emile; Bakker Joost M; Ellenbroek Bart A; Cools Alexander R; Heijnen Cobi J
Reduced tumor growth, experimental metastasis formation, and angiogenesis in rats with a hyperreactive dopaminergic system.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1465-7.
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2002: Ellenbroek Bart A; Cools Alexander R
Early maternal deprivation and prepulse inhibition: the role of the postdeprivation environment.
Pharmacology, biochemistry, and behavior 2002;73(1):177-84.
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2002: Sluyter Frans; Breivik Torbjørn; Cools Alexander
Manipulations in maternal environment reverse periodontitis in genetically predisposed rats.
Clinical and diagnostic laboratory immunology 2002;9(4):931-2.
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2002: Fontan Aurora; Rojo Ana; Sanchez Pernaute Rosario; Hernández Isabel; López Isabel; Castilla Carlos; Sanchez Albisua Julio; Perez Higueras Antonio; Al-Rashid Imad; Rabano Alberto; Gonzalo Isabel; Angeles Mena Maria; Cools Alex; Eshuis Silvia; Maguire Paul; Pruim Jan; Leenders Klaus; Garcia de Yebenes Justo
Effects of fibroblast growth factor and glial-derived neurotrophic factor on akinesia, F-DOPA uptake and dopamine cells in parkinsonian primates.
Parkinsonism & related disorders 2002;8(5):311-23.
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2002: Jost Carolina R; Van Der Zee Catharina E E M; In 't Zandt Henricus J A; Oerlemans Frank; Verheij Michel; Streijger Femke; Fransen Jack; Heerschap Arend; Cools Alexander R; Wieringa Bé
Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility.
The European journal of neuroscience 2002;15(10):1692-706.
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2002: van Oosten R V; Cools A R
Differential effects of a small, unilateral, 6-hydroxydopamine-induced nigral lesion on behavior in high and low responders to novelty.
Experimental neurology 2002;173(2):245-55.
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2002: Cools A R; Lubbers L; van Oosten R V; Andringa G
SKF 83959 is an antagonist of dopamine D1-like receptors in the prefrontal cortex and nucleus accumbens: a key to its antiparkinsonian effect in animals?
Neuropharmacology 2002;42(2):237-45.
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2001: de Bruin N M; van Luijtelaar E L; Cools A R; Ellenbroek B A
Dopamine characteristics in rat genotypes with distinct susceptibility to epileptic activity: apomorphine-induced stereotyped gnawing and novelty/amphetamine-induced locomotor stimulation.
Behavioural pharmacology 2001;12(6-7):517-25.
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2001: Cools A R
Commentary on: "Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats." Psychopharmacologia (1967) 10:316-323.
Psychopharmacology 2001;158(3):222-3.
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2001: de Bruin N M; van Luijtelaar E L; Cools A R; Ellenbroek B A
Auditory information processing in rat genotypes with different dopaminergic properties.
Psychopharmacology 2001;156(2-3):352-9.
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2001: Ellenbroek B A; Liégeois J F; Bruhwyler J; Cools A R
Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia.
The Journal of pharmacology and experimental therapeutics 2001;298(1):386-91.
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2001: Lanser M G; Ellenbroek B A; Zitman F G; Heeren D J; Cools A R
The role of medial prefrontal cortical dopamine in spontaneous flexibility in the rat.
Behavioural pharmacology 2001;12(3):163-71.
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2001: Teunisse J P; Cools A R; van Spaendonck K P; Aerts F H; Berger H J
Cognitive styles in high-functioning adolescents with autistic disorder.
Journal of autism and developmental disorders 2001;31(1):55-66.
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2001: de Bruin N M; Ellenbroek B A; van Schaijk W J; Cools A R; Coenen A M; van Luijtelaar E L
Sensory gating of auditory evoked potentials in rats: effects of repetitive stimulation and the interstimulus interval.
Biological psychology 2001;55(3):195-213.
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2001: de Bruin N M; Ellenbroek B A; van Luijtelaar E L; Cools A R; Stevens K E
Hippocampal and cortical sensory gating in rats: effects of quinpirole microinjections in nucleus accumbens core and shell.
Neuroscience 2001;105(1):169-80.
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2000: Sluyter F; Hof M; Ellenbroek B A; Degen S B; Cools A R
Genetic, sex, and early environmental effects on the voluntary alcohol intake in Wistar rats.
Pharmacology, biochemistry, and behavior 2000;67(4):801-8.
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2000: Tuinstra T; Verheij M; Willemen A; Iking J; Heeren D J; Cools A R
Retrieval of spatial information in Nijmegen high and low responders: involvement of beta-adrenergic mechanisms in the nucleus accumbens.
Behavioral neuroscience 2000;114(6):1088-95.
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2000: de Bruin N M; van Luijtelaar E L; Jansen S J; Cools A R; Ellenbroek B A
Dopamine characteristics in different rat genotypes: the relation to absence epilepsy.
Neuroscience research 2000;38(2):165-73.
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2000: Andringa G; van Oosten R V; Unger W; Hafmans T G; Veening J; Stoof J C; Cools A R
Systemic administration of the propargylamine CGP 3466B prevents behavioural and morphological deficits in rats with 6-hydroxydopamine-induced lesions in the substantia nigra.
The European journal of neuroscience 2000;12(8):3033-43.
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2000: Ellenbroek B A; Cools A R
The long-term effects of maternal deprivation depend on the genetic background.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(1):99-106.
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2000: Kolk S M; Nordquist R; Tuinhof R; Gagliardini L; Thompson B; Cools A R; Roubos E W
Localization and physiological regulation of the exocytosis protein SNAP-25 in the brain and pituitary gland of Xenopus laevis.
Journal of neuroendocrinology 2000;12(7):694-706.
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2000: Ellenbroek B A; Cools A R
Animal models for the negative symptoms of schizophrenia.
Behavioural pharmacology 2000;11(3-4):223-33.
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2000: Breivik T; Sluyter F; Hof M; Cools A
Differential susceptibility to periodontitis in genetically selected Wistar rat lines that differ in their behavioral and endocrinological response to stressors.
Behavior genetics 2000;30(2):123-30.
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2000: Arts M P; Cools A R
D1 and D2 dopamine receptor agonists improve deficits in motor programming of cats with a 6-hydroxydopamine lesion in the A8 cell group.
Behavioural brain research 2000;108(1):73-84.
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2000: Ellenbroek B A; Sluyter F; Cools A R
The role of genetic and early environmental factors in determining apomorphine susceptibility.
Psychopharmacology 2000;148(2):124-31.
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2000: Andringa G; Cools A R
The neuroprotective effects of CGP 3466B in the best in vivo model of Parkinson's disease, the bilaterally MPTP-treated rhesus monkey.
Journal of neural transmission. Supplementum 2000;(60):215-25.
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2000: Tuinstra T; Cools A R
High and low responders to novelty: effects of adrenergic agents on the regulation of accumbal dopamine under challenged and non-challenged conditions.
Neuroscience 2000;99(1):55-64.
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2000: Tuinstra T; Cools A R
Newly synthesized dopamine in the nucleus accumbens is regulated by beta-adrenergic, but not alpha-adrenergic, receptors.
Neuroscience 2000;98(4):743-7.
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1999: Spooren W P; Lubbers L; Jenks B G; Cools A R
Variation in hippocampal dynorphin b-immunoreactive mossy fiber terminal fields of apomorphine-(un)susceptible rats.
Journal of chemical neuroanatomy 1999;17(2):59-64.
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1999: Berger H J; van Es N J; van Spaendonck K P; Teunisse J P; Horstink M W; van 't Hof M A; Cools A R
Relationship between memory strategies and motor symptoms in Parkinson's disease.
Journal of clinical and experimental neuropsychology 1999;21(5):677-84.
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1999: Andringa G; Stoof J C; Cools A R
Sub-chronic administration of the dopamine D(1) antagonist SKF 83959 in bilaterally MPTP-treated rhesus monkeys: stable therapeutic effects and wearing-off dyskinesia.
Psychopharmacology 1999;146(3):328-34.
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1999: Arts M P; Cools A R
6-hydroxydopamine lesion in the A8 cell group of cats produces a short-lasting decreased accuracy in goal-directed forepaw-movements.
Behavioural brain research 1999;103(1):13-21.
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1999: Andringa G; Lubbers L; Drukarch B; Stoof J C; Cools A R
The predictive validity of the drug-naive bilaterally MPTP-treated monkey as a model of Parkinson's disease: effects of L-DOPA and the D1 agonist SKF 82958.
Behavioural pharmacology 1999;10(2):175-82.
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1999: Andringa G; Vermeulen R J; Drukarch B; Renier W O; Stoof J C; Cools A R
The validity of the pretreated, unilaterally MPTP-treated monkeys as a model of Parkinson's disease: a detailed behavioural analysis of the therapeutic and undesired effects of the D2 agonist quinpirole and the D1 agonist SKF 81297.
Behavioural pharmacology 1999;10(2):163-73.
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1999: de Bruin N M; Ellenbroek B A; Cools A R; Coenen A M; van Luijtelaar E L
Differential effects of ketamine on gating of auditory evoked potentials and prepulse inhibition in rats.
Psychopharmacology 1999;142(1):9-17.
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1999: Andringa G; Drukarch B; Leysen J E; Cools A R; Stoof J C
The alleged dopamine D1 receptor agonist SKF 83959 is a dopamine D1 receptor antagonist in primate cells and interacts with other receptors.
European journal of pharmacology 1999;364(1):33-41.
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1999: Ellenbroek B A; van Luijtelaar G; Frenken M; Cools A R
Sensory gating in rats: lack of correlation between auditory evoked potential gating and prepulse inhibition.
Schizophrenia bulletin 1999;25(4):777-88.
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1998: Hochstenbach J; van Spaendonck K P; Cools A R; Horstink M W; Mulder T
Cognitive deficits following stroke in the basal ganglia.
Clinical rehabilitation 1998;12(6):514-20.
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1998: Arts M P; Bemelmans F F; Cools A R
Role of the retrorubral nucleus in striatally elicited orofacial dyskinesia in cats: effects of muscimol and bicuculline.
Psychopharmacology 1998;140(2):150-6.
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1998: van Spaendonck K P; Berger H J; Horstink M W; Cools A R
[Cognitive deficits in Parkinson's disease]
Tijdschrift voor gerontologie en geriatrie 1998;29(4):189-95.
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1998: De Vries T J; Cools A R; Shippenberg T S
Infusion of a D-1 receptor agonist into the nucleus accumbens enhances cocaine-induced behavioural sensitization.
Neuroreport 1998;9(8):1763-8.
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1998: Arts M; Bemelmans F; Cools A
Activation of N-methyl-D-aspartate receptors in the feline retrorubral nucleus elicits orofacial dyskinesia.
European journal of pharmacology 1998;349(1):23-31.
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1998: Cools A R; Gingras M A
Nijmegen high and low responders to novelty: a new tool in the search after the neurobiology of drug abuse liability.
Pharmacology, biochemistry, and behavior 1998;60(1):151-9.
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1998: Ellenbroek B A; van den Kroonenberg P T; Cools A R
The effects of an early stressful life event on sensorimotor gating in adult rats.
Schizophrenia research 1998;30(3):251-60.
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1998: Arts M P; Cools A R
Bilateral 6-hydroxydopamine lesion in the dopaminergic A8 cell group produces long-lasting deficits in motor programming of cats.
Behavioral neuroscience 1998;112(1):102-15.
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1998: Andringa G; Vermeulen R J; Drukarch B; Stoof J C; Cools A R
Dopamine receptor subtypes as targets for the pharmacotherapy of Parkinson's disease.
Advances in pharmacology (San Diego, Calif.) 1998;42():792-5.
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1997: Mulders W H; Meek J; Hafmans T G; Cools A R
Plasticity in the stress-regulating circuit: decreased input from the bed nucleus of the stria terminalis to the hypothalamic paraventricular nucleus in Wistar rats following adrenalectomy.
The European journal of neuroscience 1997;9(11):2462-71.
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1997: Gingras M A; Cools A R
No major differences in locomotor responses to dexamphetamine in high and low responders to novelty: a study in Wistar rats.
Pharmacology, biochemistry, and behavior 1997;57(4):857-62.
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1997: Dirksen R; Ellenbroek B; van Egmond J; Cools A R
Responses to propofol in relation to GABA functionality of discrete parts of the brain of rats.
Pharmacology, biochemistry, and behavior 1997;57(4):727-35.
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1997: Gingras M A; Cools A R
Different behavioral effects of daily or intermittent dexamphetamine administration in Nijmegen high and low responders.
Psychopharmacology 1997;132(2):188-94.
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1997: Cools A R; Ellenbroek B A; Gingras M A; Engbersen A; Heeren D
Differences in vulnerability and susceptibility to dexamphetamine in Nijmegen high and low responders to novelty: a dose-effect analysis of spatio-temporal programming of behaviour.
Psychopharmacology 1997;132(2):181-7.
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1997: Ellenbroek B A; Knobbout D A; Cools A R
The role of mesolimbic and nigrostriatal dopamine in latent inhibition as measured with the conditioned taste aversion paradigm.
Psychopharmacology 1997;129(2):112-20.
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1996: van Spaendonck K P; Berger H J; Horstink M W; Borm G F; Cools A R
Memory performance under varying cueing conditions in patients with Parkinson's disease.
Neuropsychologia 1996;34(12):1159-64.
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1996: Ellenbroek B A; Lubbers L J; Cools A R
Activity of "seroquel" (ICI 204,636) in animal models for atypical properties of antipsychotics: a comparison with clozapine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(4):406-16.
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1996: Van Spaendonck K P; Berger H J; Horstink M W; Buytenhuijs E L; Cools A R
Executive functions and disease characteristics in Parkinson's disease.
Neuropsychologia 1996;34(7):617-26.
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1996: Gingras M A; Cools A R
Analysis of the biphasic locomotor response to ethanol in high and low responders to novelty: a study in Nijmegen Wistar rats.
Psychopharmacology 1996;125(3):258-64.
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1996: Prinssen E P; Heeren D J; Cools A R
d-Sulpiride inhibits oral behaviour elicited from the nucleus accumbens of freely moving rats.
Brain research bulletin 1996;39(2):101-7.
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1996: Arts M P; Groenewegen H J; Veening J G; Cools A R
Efferent projections of the retrorubral nucleus to the substantia nigra and ventral tegmental area in cats as shown by anterograde tracing.
Brain research bulletin 1996;40(3):219-28.
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1995: van Spaendonck K P; Berger H J; Horstink M W; Borm G F; Cools A R
Card sorting performance in Parkinson's Disease: a comparison between acquisition and shifting performance.
Journal of clinical and experimental neuropsychology 1995;17(6):918-25.
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1995: Cools A R; Miwa Y; Koshikawa N
Role of dopamine D1 and D2 receptors in the nucleus accumbens in jaw movements of rats: a critical role of the shell.
European journal of pharmacology 1995;286(1):41-7.
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1995: Ellenbroek B A; Geyer M A; Cools A R
The behavior of APO-SUS rats in animal models with construct validity for schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7604-11.
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1995: Mulders W H; Meek J; Schmidt E D; Hafmans T G; Cools A R
The hypothalamic paraventricular nucleus in two types of Wistar rats with different stress responses. II. Differential Fos-expression.
Brain research 1995;689(1):61-70.
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1995: Mulders W H; Meek J; Hafmans T G; Cools A R
The hypothalamic paraventricular nucleus in two types of Wistar rats with different stress responses. I. Morphometric comparison.
Brain research 1995;689(1):47-60.
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1995: Cools A R; Prinssen E P; Ellenbroek B A
The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine.
Psychopharmacology 1995;119(4):428-39.
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1995: Spooren W P; Helfrich S E; Cools A R
Interactions of the subthalamic nucleus and the subpallidal area in oro-facial dyskinesia: role of GABA and glutamate.
Psychopharmacology 1995;119(1):20-6.
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1995: Spooren W P; Haber S N; Veening J G; Cools A R
Descending efferent connections of the sub-pallidal areas in the cat: projections to the lateral habenula.
Neuroreport 1995;6(7):977-80.
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1995: Prinssen E P; Ellenbroek B A; Stamatovic B; Cools A R
Role of striatal dopamine D2 receptors in the paw test, an animal model for the therapeutic efficacy and extrapyramidal side effects of neuroleptic drugs.
Brain research 1995;673(2):283-9.
-
1994: Roozendaal B; Cools A R
Influence of the noradrenergic state of the nucleus accumbens in basolateral amygdala mediated changes in neophobia of rats.
Behavioral neuroscience 1994;108(6):1107-18.
-
1994: Prinssen E P; Ellenbroek B A; Cools A R
Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine.
European journal of pharmacology 1994;262(1-2):167-70.
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1994: Prinssen E P; Ellenbroek B A; Cools A R
Peripheral and central adrenoceptor modulation of the behavioural effects of clozapine in the paw test.
British journal of pharmacology 1994;112(3):769-74.
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1994: Buytenhuijs E L; Berger H J; Van Spaendonck K P; Horstink M W; Borm G F; Cools A R
Memory and learning strategies in patients with Parkinson's disease.
Neuropsychologia 1994;32(3):335-42.
-
1994: Prinssen E P; Balestra W; Bemelmans F F; Cools A R
Evidence for a role of the shell of the nucleus accumbens in oral behavior of freely moving rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(3 Pt 2):1555-62.
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1994: Ellenbroek B A; Prinssen E P; Cools A R
The role of serotonin receptor subtypes in the behavioural effects of neuroleptic drugs. A paw test study in rats.
The European journal of neuroscience 1994;6(1):1-8.
-
1993: Spooren W P; Veening J G; Cools A R
Descending efferent connections of the sub-pallidal areas in the cat: projections to the subthalamic nucleus, the hypothalamus, and the midbrain.
Synapse (New York, N.Y.) 1993;15(2):104-23.
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1993: Berger H J; van Spaendonck K P; Horstink M W; Buytenhuijs E L; Lammers P W; Cools A R
Cognitive shifting as a predictor of progress in social understanding in high-functioning adolescents with autism: a prospective study.
Journal of autism and developmental disorders 1993;23(2):341-59.
-
1993: Cools A R; Dierx J; Coenders C; Heeren D; Ried S; Jenks B G; Ellenbroek B
Apomorphine-susceptible and apomorphine-unsusceptible Wistar rats differ in novelty-induced changes in hippocampal dynorphin B expression and two-way active avoidance: a new key in the search for the role of the hippocampal-accumbens axis.
Behavioural brain research 1993;55(2):213-21.
-
1993: Cools A R; Ellenbroek B; Heeren D; Lubbers L
Use of high and low responders to novelty in rat studies on the role of the ventral striatum in radial maze performance: effects of intra-accumbens injections of sulpiride.
Canadian journal of physiology and pharmacology 1993;71(5-6):335-42.
-
1993: Van Spaendonck K P; Berger H J; Horstink M W; Buytenhuijs E L; Cools A R
Impaired cognitive shifting in parkinsonian patients on anticholinergic therapy.
Neuropsychologia 1993;31(4):407-11.
-
1993: Koene P; Prinssen E P; Cools A R
Involvement of the nucleus accumbens in oral behaviour in the freely moving rat.
European journal of pharmacology 1993;233(1):151-6.
-
1993: Prinssen E P; Ellenbroek B A; Stamatovic B; Cools A R
The effects of haloperidol and raclopride in the paw test are influenced similarly by SCH 39166.
European journal of pharmacology 1993;231(2):275-80.
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1993: Spooren W P; Mulders W H; Veening J G; Cools A R
The substantia innominata complex and the peripeduncular nucleus in orofacial dyskinesia: a pharmacological and anatomical study in cats.
Neuroscience 1993;52(1):17-25.
-
1993: Cools A R; Rots N Y; Ellenbroek B; de Kloet E R
Bimodal shape of individual variation in behavior of Wistar rats: the overall outcome of a fundamentally different make-up and reactivity of the brain, the endocrinological and the immunological system.
Neuropsychobiology 1993;28(1-2):100-5.
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1992: Coenders C J; Kerbusch S M; Vossen J M; Cools A R
Problem-solving behaviour in apomorphine-susceptible and unsusceptible rats.
Physiology & behavior 1992;52(2):321-6.
-
1992: van den Bos R; Charria Ortiz G A; Cools A R
Injections of the NMDA-antagonist D-2-amino-7-phosphonoheptanoic acid (AP-7) into the nucleus accumbens of rats enhance switching between cue-directed behaviours in a swimming test procedure.
Behavioural brain research 1992;48(2):165-70.
-
1992: Prinssen E P; Koene P; Heeren D; Cools A R
Jaw muscle activity, the nucleus accumbens, and dopaminergic agonists: a new approach.
Brain research bulletin 1992;28(5):775-80.
-
1992: Cools A R; Peeters B W
Differences in spike-wave discharges in two rat selection lines characterized by opposite dopaminergic activities.
Neuroscience letters 1992;134(2):253-6.
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1992: Cools A R; Prinssen E; Ellenbroek B A
Interaction between aminergic systems in mesolimbic structures: the importance of 5-HT2, D2 and D1 receptors in the olfactory tubercle for the atypical profile of neuroleptics.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():618A-619A.
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1991: Spooren W P; Piosik P A; Cools A R
Dopamine D1 receptors in the sub-commissural part of the globus pallidus and their role in oro-facial dyskinesia in cats.
European journal of pharmacology 1991;204(2):217-22.
-
1991: Cools A R; Jongen-Relo A L
Role of neostriatum and nucleus accumbens in stepping induced by apomorphine and dexamphetamine.
Brain research bulletin 1991;26(6):909-17.
-
1991: van den Bos R; Charria Ortiz G A; Bergmans A C; Cools A R
Evidence that dopamine in the nucleus accumbens is involved in the ability of rats to switch to cue-directed behaviours.
Behavioural brain research 1991;42(1):107-14.
-
1991: Spooren W P; Groenewegen H J; Cools A R
Subregions of the caudate nucleus and their in- and output channels in oro-facial dyskinesia: a behavioural and retrograde tracing study in the cat.
Brain research 1991;539(1):85-93.
-
1991: Ploeger G E; Willemen A P; Cools A R
Role of the nucleus accumbens in social memory in rats.
Brain research bulletin 1991;26(1):23-7.
-
1991: Spooren W P; Veening J G; Groenewegen H J; Cools A R
Efferent connections of the striatopallidal and amygdaloid components of the substantia innominata in the cat: projections to the nucleus accumbens and caudate nucleus.
Neuroscience 1991;44(2):431-47.
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1991: Cools A R
Differential role of mineralocorticoid and glucocorticoid receptors in the genesis of dexamphetamine-induced sensitization of mesolimbic, alpha 1 adrenergic receptors in the ventral striatum.
Neuroscience 1991;43(2-3):419-28.
-
1990: Jaspers R M; Cools A R
Behavioral correlates of a progressive dysfunctioning of the deeper layers of the colliculus superior: effects of picrotoxin.
Pharmacology, biochemistry, and behavior 1990;37(1):1-9.
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1990: Horstink M W; Berger H J; van Spaendonck K P; van den Bercken J H; Cools A R
Bimanual simultaneous motor performance and impaired ability to shift attention in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 1990;53(8):685-90.
-
1990: Cools A R
Role of neostriatal and mesostriatal or mesolimbic dopaminergic fibres in Parkinson's disease with and without dementia: prospects, concepts and facts.
Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology 1990;10(1):15-34.
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1990: Jaspers R M; de Vries T J; Cools A R
Effects of intrastriatal apomorphine on changes in switching behaviour induced by the glutamate agonist AMPA injected into the cat caudate nucleus.
Behavioural brain research 1990;37(3):247-54.
-
1990: Jaspers R M; de Vries T J; Cools A R
Enhancement in switching motor patterns following local application of the glutamate agonist AMPA into the cat caudate nucleus.
Behavioural brain research 1990;37(3):237-46.
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1990: Cools A R; Brachten R; Heeren D; Willemen A; Ellenbroek B
Search after neurobiological profile of individual-specific features of Wistar rats.
Brain research bulletin 1990;24(1):49-69.
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1990: Jaspers R M; Berkelbach van der Sprenkel J W; Tulleken C A; Cools A R
Local as well as remote functional and metabolic changes after focal ischemia in cats.
Brain research bulletin 1990;24(1):23-32.
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1989: van den Bos R; Cools A R
Involvement of the substantia innominata/ventral pallidum complex in transmitting forelimb muscular rigidity evoked from the nucleus accumbens in rats.
Neuroscience letters 1989;103(3):303-8.
-
1989: Ellenbroek B A; Willemen A P; Cools A R
Are antagonists of dopamine D1 receptors drugs that attenuate both positive and negative symptoms of schizophrenia? A pilot study in Java monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1989;2(3):191-9.
-
1989: Cools A R; Scheenen W; Eilam D; Golani I
Evidence that apomorphine and (+)-amphetamine produce different types of circling in rats.
Behavioural brain research 1989;34(1-2):111-6.
-
1989: Jaspers R M; Berkelbach van der Sprenkel J W; Cools A R
Progressive pathology of the caudate nucleus, the substantia nigra pars reticulata and the deeper layers of the colliculus superior: acute behavioural and metabolic effects of intrastriatal kainic acid.
Neuroscience 1989;28(1):159-69.
-
1989: van den Bos R; Cools A R
The involvement of the nucleus accumbens in the ability of rats to switch to cue-directed behaviours.
Life sciences 1989;44(22):1697-704.
-
1989: Spooren W P; Cuypers E; Cools A R
Oro-facial dyskinesia and the sub-commissural part of the globus pallidus in the cat: role of acetylcholine and its interaction with GABA.
Psychopharmacology 1989;99(3):381-5.
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1989: Cools A R; Spooren W; Bezemer R; Cuypers E; Jaspers R; Groenewegen H
Anatomically distinct output channels of the caudate nucleus and orofacial dyskinesia: critical role of the subcommissural part of the globus pallidus in oral dyskinesia.
Neuroscience 1989;33(3):535-42.
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1989: Berger H J; van Hoof J J; van Spaendonck K P; Horstink M W; van den Bercken J H; Jaspers R; Cools A R
Haloperidol and cognitive shifting.
Neuropsychologia 1989;27(5):629-39.
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1988: Gelissen M; Cools A
Effect of intracaudate haloperidol and apomorphine on switching motor patterns upon current behaviour of cats.
Behavioural brain research 1988;29(1-2):17-26.
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1988: Gelissen M; Cools A
Effect of increasing doses of intracaudate haloperidol upon motor expressions that require an intact substantia nigra pars reticulata and/or superior colliculus in cats.
Behavioural brain research 1988;27(3):205-14.
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1988: Jaspers R M; Cools A R
Behavioural correlates of a progressive dysfunctioning of the caudate nucleus: effects of apomorphine.
Behavioural brain research 1988;27(3):193-204.
-
1988: Ellenbroek B; Cools A R
The Paw test: an animal model for neuroleptic drugs which fulfils the criteria for pharmacological isomorphism.
Life sciences 1988;42(12):1205-13.
-
1987: Gelissen M; Cools A
Movements of cats on a rotating cylinder: role of the substantia nigra pars reticulata and the deeper layers of the superior colliculus.
Behavioural brain research 1987;25(2):83-96.
-
1987: Gelissen M; Cools A
The interrelationship between superior colliculus and substantia nigra pars reticulata in programming movements of cats: a follow-up.
Behavioural brain research 1987;25(1):1-11.
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1987: van Hoof J J; Horstink M W; Berger H J; van Spaendonck K P; Cools A R
Spasmodic torticollis: the problem of pathophysiology and assessment.
Journal of neurology 1987;234(5):322-7.
-
1986: Gelissen M; Cools A
The interrelationship between superior colliculus and substantia nigra pars reticulata in programming movements of cats.
Behavioural brain research 1986;21(2):85-93.
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1984: Cools A R; van den Bercken J H; Horstink M W; van Spaendonck K P; Berger H J
Cognitive and motor shifting aptitude disorder in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 1984;47(5):443-53.
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1976: Cools A R; Honig W M; Pijnenburg A J; Van Rossum J M
The nucleus accumbens of rats and dopaminergic mechanisms regulating locomotor behaviour.
Neuroscience letters 1976;3(5-6):335-9.
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