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Roshan Cools

Research Profile

Procedures

Concepts & Ideas

Physiology

Cognition

Disorders

Parkinson's Disease

Activities & Behaviors

Chemicals & Drugs

Anatomy

Prefrontal Cortex

Co-author Network

Publications

TOP 3
Oliver J Robinson; Barbara J Sahakian; Christina O Carlisi; Roshan Cools; Wayne C Drevets
Ventral striatum response during reward and punishment reversal learning in unmedicated major depressive disorder.
M J Crockett; A Apergis-Schoute; D Campbell-Meikeljohn; H W Chase; Luke Clark; Roshan Cools; O J Robinson; R D Rogers; Jonathan P Roiser; B J Sahakian; Ben Seymour; D Campbell-Meiklejohn; H den Ouden; Trevor W Robbins
Converging evidence for central 5-HT effects in acute tryptophan depletion.
Henry W Chase; R Swainson; Lucy Durham; Laura Benham; Roshan Cools
Feedback-related negativity codes prediction error but not behavioral adjustment during probabilistic reversal learning.

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All Publications

2012: Oliver J Robinson; Barbara J Sahakian; Christina O Carlisi; Roshan Cools; Wayne C Drevets
Ventral striatum response during reward and punishment reversal learning in unmedicated major depressive disorder.
The American journal of psychiatry 2012;169(2):152-9.
2012: M J Crockett; A Apergis-Schoute; D Campbell-Meikeljohn; H W Chase; Luke Clark; Roshan Cools; O J Robinson; R D Rogers; Jonathan P Roiser; B J Sahakian; Ben Seymour; D Campbell-Meiklejohn; H den Ouden; Trevor W Robbins
Converging evidence for central 5-HT effects in acute tryptophan depletion.
Molecular psychiatry 2012;17(2):121-3.
2011: Henry W Chase; R Swainson; Lucy Durham; Laura Benham; Roshan Cools
Feedback-related negativity codes prediction error but not behavioral adjustment during probabilistic reversal learning.
Journal of cognitive neuroscience 2011;23(4):936-46.
2010: Oliver J Robinson; Holly R Standing; Elise E DeVito; Roshan Cools; Barbara J Sahakian
Dopamine precursor depletion improves punishment prediction during reversal learning in healthy females but not males.
Psychopharmacology 2010;211(2):187-95.
2010: Oliver J Robinson; Michael J Frank; Barbara J Sahakian; Roshan Cools
Dissociable responses to punishment in distinct striatal regions during reversal learning.
NeuroImage 2010;51(4):1459-67.
2010: O J Robinson; Roshan Cools; M J Crockett; B J Sahakian
Mood state moderates the role of serotonin in cognitive biases.
Journal of psychopharmacology (Oxford, England) 2010;24(4):573-83.
2009: Philip Clatworthy; Simon J G Lewis; Laurent Brichard; Young T Hong; David Izquierdo; Luke Clark; Roshan Cools; Franklin I Aigbirhio; Jean-Claude Baron; Timothy D Fryer; Trevor W Robbins
Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(15):4690-6.
2009: Angie A Kehagia; Roshan Cools; Roger A Barker; Trevor W Robbins
Switching between abstract rules reflects disease severity but not dopaminergic status in Parkinson's disease.
Neuropsychologia 2009;47(4):1117-27.
2008: Roshan Cools; Oliver J Robinson; Barbara J Sahakian
Acute tryptophan depletion in healthy volunteers enhances punishment prediction but does not affect reward prediction.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(9):2291-9.
2008: Chris M Dodds; Ulrich Müller; Luke Clark; Anouk van Loon; Roshan Cools; Trevor W Robbins
Methylphenidate has differential effects on blood oxygenation level-dependent signal related to cognitive subprocesses of reversal learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(23):5976-82.
2008: Roshan Cools; Sasha E Gibbs; Asako Miyakawa; William J Jagust; Mark D'Esposito
Working memory capacity predicts dopamine synthesis capacity in the human striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(5):1208-12.
2008: Graham K Murray; Luke Clark; Philip R Corlett; Andrew D Blackwell; Roshan Cools; Peter B Jones; Trevor W Robbins; Luise Poustka
Incentive motivation in first-episode psychosis: a behavioural study.
BMC psychiatry 2008;8():34.
2007: Roshan Cools; Margaret Sheridan; Emily Jacobs; Mark D'Esposito
Impulsive personality predicts dopamine-dependent changes in frontostriatal activity during component processes of working memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(20):5506-14.
2007: Roshan Cools; Simon J G Lewis; Luke Clark; Roger A Barker; Trevor W Robbins
L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(1):180-9.
2006: Roshan Cools; R B Ivry; Mark D'Esposito
The human striatum is necessary for responding to changes in stimulus relevance.
Journal of cognitive neuroscience 2006;18(12):1973-83.
2006: Jonathan P Roiser; Andrew D Blackwell; Roshan Cools; Luke Clark; David C Rubinsztein; Trevor W Robbins; Barbara J Sahakian
Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(10):2264-72.
2006: Roshan Cools; Lee Altamirano; Mark D'Esposito
Reversal learning in Parkinson's disease depends on medication status and outcome valence.
Neuropsychologia 2006;44(10):1663-73.
2006: Roshan Cools
Dopaminergic modulation of cognitive function-implications for L-DOPA treatment in Parkinson's disease.
Neuroscience and biobehavioral reviews 2006;30(1):1-23.
2005: Luke Clark; Jonathan P Roiser; Roshan Cools; David C Rubinsztein; Barbara J Sahakian; Trevor W Robbins
Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity.
Psychopharmacology 2005;182(4):570-8.
2005: Roshan Cools; Andrew D Blackwell; Luke Clark; Lara Menzies; Sylvia Cox; Trevor W Robbins
Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(7):1362-73.
2004: Roshan Cools; Trevor W Robbins
Chemistry of the adaptive mind.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2004;362(1825):2871-88.
2004: Luke Clark; Roshan Cools; Trevor W Robbins
The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning.
Brain and cognition 2004;55(1):41-53.
2004: Roshan Cools; Luke Clark; Trevor W Robbins
Differential responses in human striatum and prefrontal cortex to changes in object and rule relevance.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(5):1129-35.
2003: Roshan Cools; Roger A Barker; Barbara J Sahakian; Trevor W Robbins
L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease.
Neuropsychologia 2003;41(11):1431-41.
2003: Simon J G Lewis; Roshan Cools; Trevor W Robbins; Anja Dove; Roger A Barker; Adrian M Owen
Using executive heterogeneity to explore the nature of working memory deficits in Parkinson's disease.
Neuropsychologia 2003;41(6):645-54.
2002: Roshan Cools; Luke Clark; Adrian M Owen; Trevor W Robbins
Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(11):4563-7.
2002: Roshan Cools; Elka Stefanova; Roger A Barker; Trevor W Robbins; Adrian M Owen
Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.
Brain : a journal of neurology 2002;125(Pt 3):584-94.
2001: Roshan Cools; Roger A Barker; Barbara J Sahakian; Trevor W Robbins
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands.
Cerebral cortex (New York, N.Y. : 1991) 2001;11(12):1136-43.
2001: Roshan Cools; Roger A Barker; Barbara J Sahakian; Trevor W Robbins
Mechanisms of cognitive set flexibility in Parkinson's disease.
Brain : a journal of neurology 2001;124(Pt 12):2503-12.
2000: Roshan Cools; Wiebo H Brouwer; Ritske de Jong; Cees J Slooff
Flexibility, inhibition, and planning: frontal dysfunctioning in schizophrenia.
Brain and cognition 2000;43(1-3):108-12.
1999: Ritske de Jong; E Berendsen; Roshan Cools
Goal neglect and inhibitory limitations: dissociable causes of interference effects in conflict situations.
Acta psychologica 1999;101(2-3):379-94.