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Alan Cooper

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Escherichia coli

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TOP 3
Gareth A Roberts; Augoustinos S Stephanou; Nisha Kanwar; Margaret Nutley; Garry W Blakely; Kai Chen; Alan Cooper; Laurie P Cooper; Angela Dawson; David T F Dryden
Exploring the DNA mimicry of the Ocr protein of phage T7.
Mads Gabrielsen; Kate Griffiths; Marina Ibáñez-Shimabukuro; Alan Cooper; Betina Córsico; Alan Riboldi-Tunnicliffe; Andrew J Roe; Brian O Smith; Malcolm W Kennedy
Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline.
Mads Gabrielsen; Kate Griffiths; Malcolm W Kennedy; M Florencia Rey-Burusco; Andrew J Roe; Brian O Smith; Alan Cooper; Betina Corsico
Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematode Necator americanus.

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All Publications

2012: Gareth A Roberts; Augoustinos S Stephanou; Nisha Kanwar; Margaret Nutley; Garry W Blakely; Kai Chen; Alan Cooper; Laurie P Cooper; Angela Dawson; David T F Dryden
Exploring the DNA mimicry of the Ocr protein of phage T7.
Nucleic acids research 2012;40(16):8129-43.
2012: Mads Gabrielsen; Kate Griffiths; Marina Ibáñez-Shimabukuro; Alan Cooper; Betina Córsico; Alan Riboldi-Tunnicliffe; Andrew J Roe; Brian O Smith; Malcolm W Kennedy
Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 8):939-41.
2012: Mads Gabrielsen; Kate Griffiths; Malcolm W Kennedy; M Florencia Rey-Burusco; Andrew J Roe; Brian O Smith; Alan Cooper; Betina Corsico
Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematode Necator americanus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 7):835-8.
2012: Ana Sofia Fraga; Nuno Micaelo; Margaret Nutley; Marlene Barros; Rui M M Brito; Alan Cooper; Pedro F Cruz; Ana Cristina Esteves; Euclides M V Pires
Functional and conformational changes in the aspartic protease cardosin A induced by TFE.
International journal of biological macromolecules 2012;50(2):323-30.
2012: Guilherme D Brand; Alan Cooper; Sharon M Kelly; Mariana T Q Magalhães; Jacques Nicoli; Maria L P Tinoco; Francisco J L Aragão; Carlos Bloch
Probing protein sequences as sources for encrypted antimicrobial peptides.
PloS one 2012;7(9):e45848.
2011: Swetha Vijayakrishnan; Donna P McGow; Margaret A Nutley; Olwyn Byron; Philip Callow; Alan Cooper; David Gilbert; Peter Kropholler; J Gordon Lindsay
Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly.
The Biochemical journal 2011;437(3):565-74.
2011: Nicola A G Meenan; Graeme Ball; Krystyna Bromek; Dušan Uhrín; Alan Cooper; Malcolm W Kennedy; Brian O Smith
Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of Ascaris reveals a novel fold and two discrete lipid-binding sites.
PLoS neglected tropical diseases 2011;5(4):e1040.
2010: Diane L Cameron; Joanna Jakus; Sofia R Pauleta; Graham W Pettigrew; Alan Cooper
Pressure perturbation calorimetry and the thermodynamics of noncovalent interactions in water: comparison of protein-protein, protein-ligand, and cyclodextrin-adamantane complexes.
The journal of physical chemistry. B 2010;114(49):16228-35.
2010: Alan Cooper; Malcolm W Kennedy
Biofoams and natural protein surfactants.
Biophysical chemistry 2010;151(3):96-104.
2009: Augoustinos S Stephanou; Gareth A Roberts; Laurie P Cooper; David J Clarke; Andrew R Thomson; C Logan MacKay; Margaret Nutley; Alan Cooper; David T F Dryden
Dissection of the DNA mimicry of the bacteriophage T7 Ocr protein using chemical modification.
Journal of molecular biology 2009;391(3):565-76.
2009: Cameron D Mackenzie; Brian O Smith; Annette Meister; Alfred Blume; Xiubo Zhao; Jian R Lu; Malcolm W Kennedy; Alan Cooper
Ranaspumin-2: structure and function of a surfactant protein from the foam nests of a tropical frog.
Biophysical journal 2009;96(12):4984-92.
2009: Rachel I Fleming; Cameron D Mackenzie; Alan Cooper; Malcolm W Kennedy
Foam nest components of the túngara frog: a cocktail of proteins conferring physical and biological resilience.
Proceedings. Biological sciences / The Royal Society 2009;276(1663):1787-95.
2009: Cecile M Tron; Iain W McNae; Margaret Nutley; David J Clarke; Alan Cooper; Malcolm D Walkinshaw; Robert L Baxter; Dominic J Campopiano
Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
Journal of molecular biology 2009;387(1):129-46.
2009: Rhona E McDonald; Rachel I Fleming; John G Beeley; Douglas L Bovell; Jian R Lu; Xiubo Zhao; Alan Cooper; Malcolm W Kennedy
Latherin: a surfactant protein of horse sweat and saliva.
PloS one 2009;4(5):e5726.
2008: Dimitra Serfiotis-Mitsa; Gareth A Roberts; Laurie P Cooper; John H White; Margaret Nutley; Alan Cooper; Garry W Blakely; David T F Dryden
The Orf18 gene product from conjugative transposon Tn916 is an ArdA antirestriction protein that inhibits type I DNA restriction-modification systems.
Journal of molecular biology 2008;383(5):970-81.
2007: Kevin M Guthrie; Alexis D C Parenty; Louise V Smith; Leroy Cronin; Alan Cooper
Microcalorimetry of interaction of dihydro-imidazo-phenanthridinium (DIP)-based compounds with duplex DNA.
Biophysical chemistry 2007;126(1-3):117-23.
2006: Michaela Smolle; alison prior; Audrey Elaine Brown; Alan Cooper; Olwyn Byron; J Gordon Lindsay
A new level of architectural complexity in the human pyruvate dehydrogenase complex.
The Journal of biological chemistry 2006;281(28):19772-80.
2005: Alan Cooper; Malcolm W Kennedy; Rachel I Fleming; Emma H Wilson; Hortense Videler; David L Wokosin; Tsueu-Ju Su; Rebecca J Green; Jian R Lu
Adsorption of frog foam nest proteins at the air-water interface.
Biophysical journal 2005;88(3):2114-25.
2004: Sofia pauleta; Alan Cooper; Margaret Nutley; Neil Errington; Stephen Harding; Françoise Guerlesquin; Celia F Goodhew; Isabel Moura; José J G Moura; Graham W Pettigrew
A copper protein and a cytochrome bind at the same site on bacterial cytochrome c peroxidase.
Biochemistry 2004;43(46):14566-76.
2003: Hyo-Il Jung; Alan Cooper; Richard N Perham
Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
European journal of biochemistry / FEBS 2003;270(22):4488-96.
2003: Graham W Pettigrew; Sofia pauleta; Celia F Goodhew; Alan Cooper; Margaret Nutley; Kornelia Jumel; Stephen E Harding; Cristina Costa; Ludwig Krippahl; Isabel Moura; Jose Moura
Electron transfer complexes of cytochrome c peroxidase from Paracoccus denitrificans containing more than one cytochrome.
Biochemistry 2003;42(41):11968-81.
2003: Dmitriy Alexeev; Paul N Barlow; Stella M Bury; Jean-Damien Charrier; Alan Cooper; David Hadfield; Craig Jamieson; Sharon M Kelly; Robert Layfield; R John Mayer; Helen McSparron; Nicholas C Price; Robert Ramage; Lindsay Sawyer; Bernard A Starkmann; Dusan Uhrin; Jill Wilken; Douglas W Young
Synthesis, structural and biological studies of ubiquitin mutants containing (2S, 4S)-5-fluoroleucine residues strategically placed in the hydrophobic core.
Chembiochem : a European journal of chemical biology 2003;4(9):894-6.
2003: Graham W Pettigrew; Celia F Goodhew; Alan Cooper; Margaret Nutley; Kornelia Jumel; Stephen E Harding
The electron transfer complexes of cytochrome c peroxidase from Paracoccus denitrificans.
Biochemistry 2003;42(7):2046-55.
2002: Hyo-Il Jung; Alan Cooper; Richard N Perham
Identification of key amino acid residues in the assembly of enzymes into the pyruvate dehydrogenase complex of Bacillus stearothermophilus: a kinetic and thermodynamic analysis.
Biochemistry 2002;41(33):10446-53.
2002: Lindsay McDermott; Malcolm W Kennedy; Donald P McManus; Janette E Bradley; Alan Cooper; Judith Storch
How helminth lipid-binding proteins offload their ligands to membranes: differential mechanisms of fatty acid transfer by the ABA-1 polyprotein allergen and Ov-FAR-1 proteins of nematodes and Sj-FABPc of schistosomes.
Biochemistry 2002;41(21):6706-13.
2002: Hyo-Il Jung; Simon J Bowden; Alan Cooper; Richard N Perham
Thermodynamic analysis of the binding of component enzymes in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Protein science : a publication of the Protein Society 2002;11(5):1091-100.
2001: Alan Cooper; C M Johnson; J H Lakey; Marcelo Nollmann
Heat does not come in different colours: entropy-enthalpy compensation, free energy windows, quantum confinement, pressure perturbation calorimetry, solvation and the multiple causes of heat capacity effects in biomolecular interactions.
Biophysical chemistry 2001;93(2-3):215-30.
2001: Malcolm W Kennedy; Astrid Heikema; Alan Cooper; Pamela J Bjorkman; L M Sanchez
Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteins.
The Journal of biological chemistry 2001;276(37):35008-13.
2001: Lindsay McDermott; Joyce Moore; A Brass; Nicholas C Price; Sharon M Kelly; Alan Cooper; Malcolm W Kennedy
Mutagenic and chemical modification of the ABA-1 allergen of the nematode Ascaris: consequences for structure and lipid binding properties.
Biochemistry 2001;40(33):9918-26.
2001: Tino Krell; John Maclean; Deborah J Boam; Alan Cooper; Marina Resmini; Keith Brocklehurst; Sharon M Kelly; Nicholas C Price; Adrian J Lapthorn; John R Coggins
Biochemical and X-ray crystallographic studies on shikimate kinase: the important structural role of the P-loop lysine.
Protein science : a publication of the Protein Society 2001;10(6):1137-49.
2001: alison prior; J T Jones; V C Blok; J Beauchamp; Lindsay McDermott; Alan Cooper; Malcolm W Kennedy
A surface-associated retinol- and fatty acid-binding protein (Gp-FAR-1) from the potato cyst nematode Globodera pallida: lipid binding activities, structural analysis and expression pattern.
The Biochemical journal 2001;356(Pt 2):387-94.
2000: Y Xia; Heather J Spence; Joyce Moore; Nicholas B Heaney; Lindsay McDermott; Alan Cooper; D G Watson; B Mei; Richard W Komuniecki; Malcolm W Kennedy
The ABA-1 allergen of Ascaris lumbricoides: sequence polymorphism, stage and tissue-specific expression, lipid binding function, and protein biophysical properties.
Parasitology 2000;120 ( Pt 2)():211-24.
1999: DA Schiffmann; J H White; Alan Cooper; Margaret Nutley; Stephen E Harding; K Jumel; R Solari; Keith Ray; nicholas gay
Formation and biochemical characterization of tube/pelle death domain complexes: critical regulators of postreceptor signaling by the Drosophila toll receptor.
Biochemistry 1999;38(36):11722-33.
1999: MD Kirkitadze; Malgorzata Krych; Dusan Uhrin; David T F Dryden; Brian O Smith; Alan Cooper; Xuefeng Wang; Richard Hauhart; John P Atkinson; Paul N Barlow
Independently melting modules and highly structured intermodular junctions within complement receptor type 1.
Biochemistry 1999;38(22):7019-31.
1999: Joyce Moore; Lindsay McDermott; Nicholas C Price; Sharon M Kelly; Alan Cooper; Malcolm W Kennedy
Sequence-divergent units of the ABA-1 polyprotein array of the nematode Ascaris suum have similar fatty-acid- and retinol-binding properties but different binding-site environments.
The Biochemical journal 1999;340 ( Pt 1)():337-43.
1999: Lindsay McDermott; Alan Cooper; Malcolm W Kennedy
Novel classes of fatty acid and retinol binding protein from nematodes.
Molecular and cellular biochemistry 1999;192(1-2):69-75.
1997: Malcolm W Kennedy; L H Garside; L E Goodrick; Lindsay McDermott; A Brass; Nicholas C Price; Sharon M Kelly; Alan Cooper; Janette E Bradley
The Ov20 protein of the parasitic nematode Onchocerca volvulus. A structurally novel class of small helix-rich retinol-binding proteins.
The Journal of biological chemistry 1997;272(47):29442-8.
1996: Tino Krell; M J Horsburgh; Alan Cooper; Sharon M Kelly; John R Coggins
Localization of the active site of type II dehydroquinases. Identification of a common arginine-containing motif in the two classes of dehydroquinases.
The Journal of biological chemistry 1996;271(40):24492-7.
1995: Malcolm W Kennedy; Collette Britton; Nicholas C Price; Sharon M Kelly; Alan Cooper
The DvA-1 polyprotein of the parasitic nematode Dictyocaulus viviparus. A small helix-rich lipid-binding protein.
The Journal of biological chemistry 1995;270(33):19277-81.
1995: Malcolm W Kennedy; A Brass; A B McCruden; Nicholas C Price; Sharon M Kelly; Alan Cooper
The ABA-1 allergen of the parasitic nematode Ascaris suum: fatty acid and retinoid binding function and structural characterization.
Biochemistry 1995;34(20):6700-10.
1995: Malcolm W Kennedy; J E Allen; A S Wright; A B McCruden; Alan Cooper
The gp15/400 polyprotein antigen of Brugia malayi binds fatty acids and retinoids.
Molecular and biochemical parasitology 1995;71(1):41-50.
1992: Colin Kleanthous; R Deka; K Davis; Sharon M Kelly; Alan Cooper; S E Harding; Nicholas C Price; Alastair R Hawkins; John R Coggins
A comparison of the enzymological and biophysical properties of two distinct classes of dehydroquinase enzymes.
The Biochemical journal 1992;282 ( Pt 3)():687-95.
1991: C M Johnson; Alan Cooper; Alistair J P Brown
A comparison of the reactivity and stability of wild type and His388----Gln mutant phosphoglycerate kinase from yeast.
European journal of biochemistry / FEBS 1991;202(3):1157-64.
1991: Colin Kleanthous; M Reilly; Alan Cooper; S Kelly; Nicholas C Price; John R Coggins
Stabilization of the shikimate pathway enzyme dehydroquinase by covalently bound ligand.
The Journal of biological chemistry 1991;266(17):10893-8.