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Janet Allen

Research Profile

Chemicals & Drugs

Anatomy

Physiology

Devices

Insulin Infusion Systems

Concepts & Ideas

Disorders

Type 1 Diabetes Mellitus

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Publications

TOP 3
Kavita Kumareswaran; Janet M Allen; Stephanie A Amiel; Soren Brage; Karen Caldwell; Daniela Elleri; Roman Hovorka; Marianna Nodale; Philippa Raymond-Barker; Kate Westgate; Malgorzata E Wilinska; Helen R Murphy
Physical Activity Energy Expenditure and Glucose Control in Pregnant Women With Type 1 Diabetes: Is 30 minutes of daily exercise enough?
Daniela Elleri; Ahmad Haidar; Carlo L Acerini; Janet M Allen; Karen Caldwell; Peiyao Cheng; David B Dunger; Craig Kollman; Kavita Kumareswaran; Lalantha Leelarathna; Helen R Murphy; Marianna Nodale; Malgorzata E Wilinska; Roman Hovorka
Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes: randomized clinical trial.
Kavita Kumareswaran; Marianna Nodale; Malgorzata E Wilinska; Janet M Allen; Stephanie A Amiel; Karen Caldwell; Daniela Elleri; Roman Hovorka; Helen R Murphy
Accuracy of continuous glucose monitoring during exercise in type 1 diabetes pregnancy.

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All Publications

2013: Kavita Kumareswaran; Janet M Allen; Stephanie A Amiel; Soren Brage; Karen Caldwell; Daniela Elleri; Roman Hovorka; Marianna Nodale; Philippa Raymond-Barker; Kate Westgate; Malgorzata E Wilinska; Helen R Murphy
Physical Activity Energy Expenditure and Glucose Control in Pregnant Women With Type 1 Diabetes: Is 30 minutes of daily exercise enough?
Diabetes care 2013;36(5):1095-101.
2013: Daniela Elleri; Ahmad Haidar; Carlo L Acerini; Janet M Allen; Karen Caldwell; Peiyao Cheng; David B Dunger; Craig Kollman; Kavita Kumareswaran; Lalantha Leelarathna; Helen R Murphy; Marianna Nodale; Malgorzata E Wilinska; Roman Hovorka
Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes: randomized clinical trial.
Diabetes care 2013;36(4):838-44.
2013: Kavita Kumareswaran; Marianna Nodale; Malgorzata E Wilinska; Janet M Allen; Stephanie A Amiel; Karen Caldwell; Daniela Elleri; Roman Hovorka; Helen R Murphy
Accuracy of continuous glucose monitoring during exercise in type 1 diabetes pregnancy.
Diabetes technology & therapeutics 2013;15(3):223-9.
2012: Daniela Elleri; Carlo L Acerini; Janet M Allen; Martina Biagioni; Karen Caldwell; David B Dunger; Kavita Kumareswaran; Lalantha Leelarathna; Marianna Nodale; Malgorzata E Wilinska; Roman Hovorka
Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes.
Pediatric diabetes 2012;13(6):449-53.
2012: William Harnett; Janet M Allen; Helen Goodridge; Margaret Harnett
Receptor usage by the Acanthocheilonema viteae-derived immunomodulator, ES-62.
Experimental parasitology 2012;132(1):97-102.
2011: Daniela Elleri; Janet M Allen; David D Dunger; Roman Hovorkea
Closed-loop in children with type 1 diabetes: specific challenges.
Diabetes research and clinical practice 2011;93 Suppl 1():S131-5.
2011: Daniela Elleri; Janet M Allen; Marianna Nodale; Malgorzata E Wilinska; Jasdip S Mangat; Anne Mette F Larsen; Carlo L Acerini; David D Dunger; Roman Hovorka
Automated overnight closed-loop glucose control in young children with type 1 diabetes.
Diabetes technology & therapeutics 2011;13(4):419-24.
2011: Helen R Murphy; Daniela Elleri; Janet M Allen; Julie Harris; David Simmons; Gerry Rayman; Rosemary Temple; David D Dunger; Ahmad Haidar; Marianna Nodale; Malgorzata E Wilinska; Roman Hovorka
Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes.
Diabetes care 2011;34(2):406-11.
2011: Roman Hovorka; Kavita Kumareswaran; Julie Harris; Janet M Allen; Daniela Elleri; Dongyuan Xing; Craig Kollman; Marianna Nodale; Helen R Murphy; David D Dunger; Stephanie A Amiel; Simon R Heller; Malgorzata E Wilinska; Mark L Evans
Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies.
BMJ (Clinical research ed.) 2011;342():d1855.
2010: Daniela Elleri; Janet M Allen; M Nodale; Malgorzata E Wilinska; Carlo L Acerini; David D Dunger; Roman Hovorka
Suspended insulin infusion during overnight closed-loop glucose control in children and adolescents with Type 1 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2010;27(4):480-4.
2010: Roman Hovorka; Janet M Allen; Daniela Elleri; Ludovic J Chassin; Julie Harris; Dongyuan Xing; Craig Kollman; Tomas Hovorka; Anne Mette F Larsen; Marianna Nodale; Alessandra De Palma; Malgorzata E Wilinska; Carlo L Acerini; David D Dunger
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial.
Lancet 2010;375(9716):743-51.
2010: Malgorzata E Wilinska; Ludovic J Chassin; Carlo L Acerini; Janet M Allen; David D Dunger; Roman Hovorka
Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes.
Journal of diabetes science and technology 2010;4(1):132-44.
2010: Daniela Elleri; Carlo L Acerini; Janet M Allen; Josephine Hayes; Claire Pesterfield; Malgorzata E Wilinska; David D Dunger; Roman Hovorka
Parental attitudes towards overnight closed-loop glucose control in children with type 1 diabetes.
Diabetes technology & therapeutics 2010;12(1):35-9.
2009: Daniela Elleri; Carlo L Acerini; Janet M Allen; Anne-Mette F Larsen; Malgorzata E Wilinska; David D Dunger; Roman Hovorka
Effect of delay on measurement of blood glucose levels in young subjects with type 1 diabetes.
Diabetes research and clinical practice 2009;86(2):e31-3.
2009: Malgorzata E Wilinska; Erwin S Budiman; Marc B Taub; Daniela Elleri; Janet M Allen; Carlo L Acerini; David D Dunger; Roman Hovorka
Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies.
Journal of diabetes science and technology 2009;3(5):1109-20.
2007: Gillian Borland; Adrienne L Edkins; Mridu Acharya; Johanne Matheson; Lindsey J White; Janet M Allen; Jean-Yves Bonnefoy; Bradford W Ozanne; William Cushley
alphavbeta5 integrin sustains growth of human pre-B cells through an RGD-independent interaction with a basic domain of the CD23 protein.
The Journal of biological chemistry 2007;282(37):27315-26.
2005: R Andres Floto; Menna R Clatworthy; Karen R Heilbronn; Dalya R Rosner; Paul A MacAry; Angela Rankin; Paul J Lehner; Willem H Ouwehand; Janet M Allen; Nicholas A Watkins; Kenneth G C Smith
Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts.
Nature medicine 2005;11(10):1056-8.
2002: Katherine B Bodman-Smith; Alirio J Melendez; Ian Campbell; Patrick T Harrison; Janet M Allen; John G Raynes
C-reactive protein-mediated phagocytosis and phospholipase D signalling through the high-affinity receptor for immunoglobulin G (FcgammaRI).
Immunology 2002;107(2):252-60.
2002: Angus J M Cameron; Kenneth J McDonald; Margaret M Harnett; Janet M Allen
Differentiation of the human monocyte cell line, U937, with dibutyryl cyclicAMP induces the expression of the inhibitory Fc receptor, FcgammaRIIb.
Immunology letters 2002;83(3):171-9.
2002: Kenneth J McDonald; Angus J M Cameron; Janet M Allen; Alan Jardine
Expression of Fc alpha/mu receptor by human mesangial cells: a candidate receptor for immune complex deposition in IgA nephropathy.
Biochemical and biophysical research communications 2002;290(1):438-42.
2001: Alirio J Melendez; L Bruetschy; R Andres Floto; Margaret M Harnett; Janet M Allen
Functional coupling of FcgammaRI to nicotinamide adenine dinucleotide phosphate (reduced form) oxidative burst and immune complex trafficking requires the activation of phospholipase D1.
Blood 2001;98(12):3421-8.
2001: J C Bournat; Janet M Allen
Regulation of the Y1 neuropeptide Y receptor gene expression in PC12 cells.
Brain research. Molecular brain research 2001;90(2):149-64.
2001: Alirio J Melendez; Margaret M Harnett; Janet M Allen
Crosstalk between ARF6 and protein kinase Calpha in Fc(gamma)RI-mediated activation of phospholipase D1.
Current biology : CB 2001;11(11):869-74.
2000: Jim C Norman; Janet M Allen
Endocytosis of FcgammaRI is regulated by two distinct signalling pathways.
FEBS letters 2000;484(3):179-83.
2000: Alirio J Melendez; E Carlos-Dias; Mark Gosink; Janet M Allen; L Takacs
Human sphingosine kinase: molecular cloning, functional characterization and tissue distribution.
Gene 2000;251(1):19-26.
2000: Oleg N Osipenko; AP Barrie; Janet M Allen; Alison M Gurney
Pituitary adenylyl cyclase-activating peptide activates multiple intracellular signaling pathways to regulate ion channels in PC12 cells.
The Journal of biological chemistry 2000;275(22):16626-31.
1999: DJ Gillooly; Alirio J Melendez; A R Hockaday; Margaret M Harnett; Janet M Allen
Endocytosis and vesicular trafficking of immune complexes and activation of phospholipase D by the human high-affinity IgG receptor requires distinct phosphoinositide 3-kinase activities.
The Biochemical journal 1999;344 Pt 2():605-11.
1999: Alirio J Melendez; Margaret M Harnett; Janet M Allen
FcgammaRI activation of phospholipase Cgamma1 and protein kinase C in dibutyryl cAMP-differentiated U937 cells is dependent solely on the tyrosine-kinase activated form of phosphatidylinositol-3-kinase.
Immunology 1999;98(1):1-8.
1999: Angus J M Cameron; Janet M Allen
The human high-affinity immunoglobulin G receptor activates SH2-containing inositol phosphatase (SHIP).
Immunology 1999;97(4):641-7.
1999: Alirio J Melendez; Margaret M Harnett; Janet M Allen
Differentiation-dependent switch in protein kinase C isoenzyme activation by FcgammaRI, the human high-affinity receptor for immunoglobulin G.
Immunology 1999;96(3):457-64.
1998: S N Symeonides; M J Morris; J C Bournat; Janet M Allen
Leptin regulation of expression of neuropeptide Y and its receptor.
Biochemical Society transactions 1998;26(3):S203.
1998: M A Sim; AP Barrie; Janet M Allen
Extracellular signal-regulated kinase 1 or 2 activation by Fc gamma RI aggregation in U937 cells.
Biochemical Society transactions 1998;26(3):S198.
1998: Jim C Norman; Patrick T Harrison; W Davis; R Andres Floto; Janet M Allen
Lysosomal routing of Fc gamma RI from early endosomes requires recruitment of tyrosine kinases.
Immunology 1998;94(1):48-55.
1998: Alirio J Melendez; R Andres Floto; DJ Gillooly; Margaret M Harnett; Janet M Allen
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking.
The Journal of biological chemistry 1998;273(16):9393-402.
1998: Alirio J Melendez; DJ Gillooly; Margaret M Harnett; Janet M Allen
Aggregation of the human high affinity immunoglobulin G receptor (FcgammaRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2169-74.
1998: Patrick T Harrison; Janet M Allen
High affinity IgG binding by FcgammaRI (CD64) is modulated by two distinct IgSF domains and the transmembrane domain of the receptor.
Protein engineering 1998;11(3):225-32.
1998: Alirio J Melendez; R Andres Floto; Angus J M Cameron; DJ Gillooly; Margaret M Harnett; Janet M Allen
A molecular switch changes the signalling pathway used by the Fc gamma RI antibody receptor to mobilise calcium.
Current biology : CB 1998;8(4):210-21.
1998: Patrick T Harrison; I W Campbell; Janet M Allen
Use of GPI-anchored proteins to study biomolecular interactions by surface plasmon resonance.
FEBS letters 1998;422(3):301-6.
1998: Timothy J Scase; M Fred Heath; Janet M Allen; S O Sage; Richard J Evans
Identification of a P2X1 purinoceptor expressed on human platelets.
Biochemical and biophysical research communications 1998;242(3):525-8.
1997: AP Barrie; A M Clohessy; C S Buensuceso; M V Rogers; Janet M Allen
Pituitary adenylyl cyclase-activating peptide stimulates extracellular signal-regulated kinase 1 or 2 (ERK1/2) activity in a Ras-independent, mitogen-activated protein Kinase/ERK kinase 1 or 2-dependent manner in PC12 cells.
The Journal of biological chemistry 1997;272(32):19666-71.
1997: Angus J M Cameron; Janet M Allen
Differential expression of the human high affinity IgG receptor Fc gamma RI and associated signalling molecules in differentiated U937 monocyte cells.
Biochemical Society transactions 1997;25(3):502S.
1997: Melanie McCarthy-Troke; Patrick T Harrison; I Campbell; Janet M Allen
Scanning alanine mutagenesis of the second Ig domain of Fc gamma RI indicates critical residues for ligand recognition.
Biochemical Society transactions 1997;25(2):361S.
1997: Alirio J Melendez; M M Harnett; Janet M Allen
Differentiation dependent switch in signalling pathways initiated by Fc gamma RI.
Biochemical Society transactions 1997;25(2):254S.
1997: DJ Gillooly; Janet M Allen
The human high affinity IgG receptor (Fc gamma RI) signals through the immunoreceptor tyrosine-based activation motif (ITAM) of the gamma chain of Fc epsilon RI.
Biochemical Society transactions 1997;25(2):215S.
1997: R Andres Floto; B Somasundaram; Janet M Allen; Martyn P Mahaut-Smith
Fcgamma receptor I activation triggers a novel Ca2+-activated current selective for monovalent cations in the human monocytic cell line, U937.
The Journal of biological chemistry 1997;272(8):4753-8.
1996: R A Floto; Martyn P Mahaut-Smith; Janet M Allen; B Somasundaram
Differentiation of the human monocytic cell line U937 results in an upregulation of the calcium release-activated current, ICRAC.
The Journal of physiology 1996;495 ( Pt 2)():331-8.
1996: Patrick T Harrison; Janet M Allen
Domain swap chimeras to study the binding of IgG by Fc gamma RI, the high affinity receptor for IgG.
Biochemical Society transactions 1996;24(1):144S.
1996: M J Hutchinson; Janet M Allen
The functional role of the gamma-chain cysteine in Fc gamma RI-mediated phagocytosis using co-transfected COS-7 cells.
Biochemical Society transactions 1996;24(1):114S.
1995: R A Floto; Martyn P Mahaut-Smith; B Somasundaram; Janet M Allen
IgG-induced Ca2+ oscillations in differentiated U937 cells; a study using laser scanning confocal microscopy and co-loaded fluo-3 and fura-red fluorescent probes.
Cell calcium 1995;18(5):377-89.
1995: Patrick T Harrison; Lise Bjørkhaug; M J Hutchinson; Janet M Allen
The interaction between human Fc gamma RI and the gamma-chain is mediated solely via the 21 amino acid transmembrane domain of Fc gamma RI.
Molecular membrane biology 1995;12(4):309-12.
1995: N Holliday; D Balbi; A Pance; Janet M Allen
Nerve growth factor regulation of a late response gene--neuropeptide Y.
Biochemical Society transactions 1995;23(2):226S.
1995: W Davis; E L Halliwell; Stewart O Sage; Janet M Allen
Increased capacity for store regulated calcium influx in U937 cells differentiated by treatment with dibutyryl cAMP.
Cell calcium 1995;17(5):345-53.
1995: M J Hutchinson; Patrick T Harrison; R Andres Floto; Janet M Allen
Fc gamma receptor-mediated phagocytosis requires tyrosine kinase activity and is ligand independent.
European journal of immunology 1995;25(2):481-7.
1995: W Davis; Patrick T Harrison; M J Hutchinson; Janet M Allen
Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis.
The EMBO journal 1995;14(3):432-41.
1995: R R Lim; M R Bloomfield; A M Johnson; Janet M Allen
Dopamine concentrations in PC12 cells following neuronal differentiation induced by NGF or VIP.
Biochemical Society transactions 1995;23(1):46S.
1995: M J Hutchinson; Patrick T Harrison; Janet M Allen
Transmembrane association with gamma-chain is required for Fc gamma RI-mediated phagocytosis in transfected COS cells.
Biochemical Society transactions 1995;23(1):121S.
1995: W Davis; Patrick T Harrison; Janet M Allen
Functional necessity for binding of monomeric IgG to permit internalisation of Fc gamma RI.
Biochemical Society transactions 1995;23(1):120S.
1995: A Pance; D Balbi; N Holliday; Janet M Allen
Effect of cAMP elevation on the NPY gene transcription.
Biochemical Society transactions 1995;23(1):47S.
1994: R A Colbert; D Balbi; A Johnson; J A Bailey; Janet M Allen
Vasoactive intestinal peptide stimulates neuropeptide Y gene expression and causes neurite extension in PC12 cells through independent mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(11 Pt 2):7141-7.
1994: Patrick T Harrison; W Davis; J C Norman; Austin R Hockaday; Janet M Allen
Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis.
The Journal of biological chemistry 1994;269(39):24396-402.
1994: Patrick T Harrison; M J Hutchinson; Janet M Allen
A convenient method for the construction and expression of GPI-anchored proteins.
Nucleic acids research 1994;22(18):3813-4.
1994: W Davis; Stewart O Sage; Janet M Allen
Cytosolic calcium elevation in response to Fc receptor cross-linking in undifferentiated and differentiated U937 cells.
Cell calcium 1994;16(1):29-36.
1994: M Socolovsky; Austin R Hockaday; Janet M Allen
Human high-affinity Fc IgG receptor (Fc gamma RI)-mediated phagocytosis and pinocytosis in COS cells.
European journal of cell biology 1994;64(1):29-44.
1994: D Balbi; Janet M Allen
Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells.
Brain research. Molecular brain research 1994;23(4):310-6.
1993: W Davis; Stewart O Sage; Janet M Allen
Fc receptor mediated calcium signalling in differentiated and undifferentiated U937 cells.
Biochemical Society transactions 1993;21(4):336S.
1993: Patrick T Harrison; W Davis; Janet M Allen
Stimulation of endocytosis by antibody cross-linking of the human high affinity receptor for IgG in COS cells is independent of the cytoplasmic and transmembrane domains.
Biochemical Society transactions 1993;21(4):335S.
1993: Patrick T Harrison; Janet M Allen
Formation of a glycosylinositol-phosphate anchored high affinity Fc-receptor in COS cells.
Biochemical Society transactions 1993;21(4):334S.
1988: H D Woodward; Janet M Allen; W J Lennarz
3-Hydroxy-3-methylglutaryl-coenzyme A reductase of the sea urchin embryo. Deduced structure and regulatory properties.
The Journal of biological chemistry 1988;263(34):18411-8.
1988: H D Woodward; Janet M Allen; W J Lennarz
3-Hydroxy-3-methylglutaryl coenzyme A reductase in the sea urchin embryo is developmentally regulated.
The Journal of biological chemistry 1988;263(5):2513-7.