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Nicholas Allen

Research Profile

Living Beings

Phenomena

Methylation

Physiology

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R Patani; A J Hollins; T M Wishart; C A Puddifoot; S Alvarez; A R de Lera; David J A Wyllie; D A S Compston; Roger A Pedersen; T H Gillingwater; Giles E Hardingham; Nicholas D Allen; Siddharthan Chandran
Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.
Rickie Patani; Alastair Compston; Clare A Puddifoot; David J A Wyllie; Giles E Hardingham; Nicholas D Allen; Siddharthan Chandran
Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.
Bilada Bilican; Christelle Fiore-Heriche; Alastair Compston; Nicholas D Allen; Siddharthan Chandran
Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level.

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All Publications

2011: R Patani; A J Hollins; T M Wishart; C A Puddifoot; S Alvarez; A R de Lera; David J A Wyllie; D A S Compston; Roger A Pedersen; T H Gillingwater; Giles E Hardingham; Nicholas D Allen; Siddharthan Chandran
Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state.
Nature communications 2011;2():214.
2009: Rickie Patani; Alastair Compston; Clare A Puddifoot; David J A Wyllie; Giles E Hardingham; Nicholas D Allen; Siddharthan Chandran
Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.
PloS one 2009;4(10):e7327.
2008: Bilada Bilican; Christelle Fiore-Heriche; Alastair Compston; Nicholas D Allen; Siddharthan Chandran
Induction of Olig2 precursors by FGF involves BMP signalling blockade at the Smad level.
PloS one 2008;3(8):e2863.
2007: Alexis Joannides; Daniel J Webber; Olivier Raineteau; Claire Kelly; Karen-Amanda Irvine; Colin Watts; Anne E Rosser; Paul J Kemp; William F Blakemore; Alastair Compston; Maeve A Caldwell; Nicholas D Allen; Siddharthan Chandran
Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells.
Brain : a journal of neurology 2007;130(Pt 5):1263-75.
2007: Alexis Joannides; Christelle Fiore-Hériché; Alysia A Battersby; Pandula Athauda-Arachchi; Isabelle A Bouhon; Lydia Williams; Kristine Westmore; Paul J Kemp; Alastair Compston; Nicholas D Allen; Siddharthan Chandran
A scaleable and defined system for generating neural stem cells from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2007;25(3):731-7.
2006: Isabelle A Bouhon; Alexis Joannides; Hidemasa Kato; Siddharthan Chandran; Nicholas D Allen
Embryonic stem cell-derived neural progenitors display temporal restriction to neural patterning.
Stem cells (Dayton, Ohio) 2006;24(8):1908-13.
2005: Isabelle A Bouhon; Hidemasa Kato; Siddharthan Chandran; Nicholas D Allen
Neural differentiation of mouse embryonic stem cells in chemically defined medium.
Brain research bulletin 2005;68(1-2):62-75.
2005: Laura Calò; Maria Grazia Spillantini; F Nicoletti; Nicholas D Allen
Nurr1 co-localizes with EphB1 receptors in the developing ventral midbrain, and its expression is enhanced by the EphB1 ligand, ephrinB2.
Journal of neurochemistry 2005;92(2):235-45.
2003: Siddharthan Chandran; Hidemasa Kato; Dianne Gerreli; Alastair Compston; Clive Svendsen; Nicholas D Allen
FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway.
Development (Cambridge, England) 2003;130(26):6599-609.
2003: Lorenza Ciani; Anjla Patel; Nicholas D Allen; Charles ffrench-Constant
Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.
Molecular and cellular biology 2003;23(10):3575-82.
2002: Dan Ma; Nicholas D Allen; Yfke C H Van Bergen; Camilla M E Jones; Michael J Baum; Eric B Keverne; peter anthony brennan
Selective ablation of olfactory receptor neurons without functional impairment of vomeronasal receptor neurons in OMP-ntr transgenic mice.
The European journal of neuroscience 2002;16(12):2317-23.
2002: Alexandra Erven; Michael J Skynner; Katsuzumi Okumura; Shin-ichiro Takebayashi; Steve D M Brown; Karen P Steel; Nicholas D Allen
A novel stereocilia defect in sensory hair cells of the deaf mouse mutant Tasmanian devil.
The European journal of neuroscience 2002;16(8):1433-41.
2002: Anthony R Isles; Michael J Baum; Dan Ma; Abigail Szeto; Eric B Keverne; Nicholas D Allen
A possible role for imprinted genes in inbreeding avoidance and dispersal from the natal area in mice.
Proceedings. Biological sciences / The Royal Society 2002;269(1492):665-70.
2001: Katrin A Mooslehner; Pok Man Chan; Weiming XU; L Liu; C Smadja; Trevor Humby; Nicholas D Allen; Lawrence S Wilkinson; Piers C Emson
Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism.
Molecular and cellular biology 2001;21(16):5321-31.
2001: Anthony R Isles; Dan Ma; C Milsom; Michael J Skynner; W Cui; J Clark; Eric B Keverne; Nicholas D Allen
Conditional ablation of neurones in transgenic mice.
Journal of neurobiology 2001;47(3):183-93.
2001: Anthony R Isles; M J Baum; Dan Ma; Eric B Keverne; Nicholas D Allen
Urinary odour preferences in mice.
Nature 2001;409(6822):783-4.
2000: H Kato; Nicholas D Allen; Piers C Emson; Hiroshi Kiyama
GAP-43 N-terminal translocation signal targets beta-galactosidase to developing axons in a pan-neuronal transgenic mouse line.
Brain research. Developmental brain research 2000;121(1):109-12.
1999: Jean-Rémi Pape; Michael J Skynner; Nicholas D Allen; Allan E Herbison
Transgenics identify distal 5'- and 3'-sequences specifying gonadotropin-releasing hormone expression in adult mice.
Molecular endocrinology (Baltimore, Md.) 1999;13(12):2203-11.
1999: Michael J Skynner; R Slater; JA Sim; Nicholas D Allen; Allan E Herbison
Promoter transgenics reveal multiple gonadotropin-releasing hormone-I-expressing cell populations of different embryological origin in mouse brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(14):5955-66.
1999: Katrin A Mooslehner; Nicholas D Allen
Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(3):218-24.
1999: Michael J Skynner; D J Drage; Wendy Dean; S Turner; D J Watt; Nicholas D Allen
Transgenic mice ubiquitously expressing human placental alkaline phosphatase (PLAP): an additional reporter gene for use in tandem with beta-galactosidase (lacZ).
The International journal of developmental biology 1999;43(1):85-90.
1997: F L Sun; Wendy Dean; Gavin Kelsey; Nicholas D Allen; Wolf Reik
Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome.
Nature 1997;389(6653):809-15.
1997: Robert Feil; M D Boyano; Nicholas D Allen; Gavin Kelsey
Parental chromosome-specific chromatin conformation in the imprinted U2af1-rs1 gene in the mouse.
The Journal of biological chemistry 1997;272(33):20893-900.
1995: Nicholas D Allen; K Logan; G Lally; D J Drage; M L Norris; E B Keverne
Distribution of parthenogenetic cells in the mouse brain and their influence on brain development and behavior.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10782-6.
1995: Robert Feil; M A Handel; Nicholas D Allen; Wolf Reik
Chromatin structure and imprinting: developmental control of DNase-I sensitivity in the mouse insulin-like growth factor 2 gene.
Developmental genetics 1995;17(3):240-52.
1994: Robert Feil; Jörn Walter; Nicholas D Allen; Wolf Reik
Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes.
Development (Cambridge, England) 1994;120(10):2933-43.
1994: Nicholas D Allen; Sheila C Barton; Kathy Hilton; M L Norris; M Azim Surani
A functional analysis of imprinting in parthenogenetic embryonic stem cells.
Development (Cambridge, England) 1994;120(6):1473-82.
1994: Wolf Reik; Nicholas D Allen
Genomic imprinting. Imprinting with and without methylation.
Current biology : CB 1994;4(2):145-7.
1993: M Azim Surani; H Sasaki; A C Ferguson-Smith; Nicholas D Allen; Sheila C Barton; Peter A Jones; Wolf Reik
The inheritance of germline-specific epigenetic modifications during development.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993;339(1288):165-72.
1993: H Sasaki; Nicholas D Allen; M Azim Surani
DNA methylation and genomic imprinting in mammals.
EXS 1993;64():469-86.
1992: R K Kothary; Nicholas D Allen; Sheila C Barton; M L Norris; M Azim Surani
Factors affecting cellular mosaicism in the expression of a lacZ transgene in two-cell stage mouse embryos.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1992;70(10-11):1097-104.
1990: Nicholas D Allen; E B Keverne; M Azim Surani
A position-dependent transgene reveals patterns of gene expression in the developing brain.
Brain research. Developmental brain research 1990;55(2):181-90.
1990: Nicholas D Allen; M L Norris; M Azim Surani
Epigenetic control of transgene expression and imprinting by genotype-specific modifiers.
Cell 1990;61(5):853-61.
1990: M Azim Surani; Nicholas D Allen; Sheila C Barton; Reinald Fundele; S K Howlett; M L Norris; Wolf Reik
Developmental consequences of imprinting of parental chromosomes by DNA methylation.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1990;326(1235):313-27.
1990: M Azim Surani; R Kothary; Nicholas D Allen; P B Singh; Reinald Fundele; A C Ferguson-Smith; Sheila C Barton
Genome imprinting and development in the mouse.
Development (Cambridge, England). Supplement 1990;():89-98.
1989: R K Kothary; Nicholas D Allen; M A Surani
Transgenes as molecular probes of mammalian developmental genetics.
Oxford surveys on eukaryotic genes 1989;6():145-78.
1988: Nicholas D Allen; D G Cran; Sheila C Barton; S Hettle; Wolf Reik; M Azim Surani
Transgenes as probes for active chromosomal domains in mouse development.
Nature 1988;333(6176):852-5.
1988: M Azim Surani; Wolf Reik; Nicholas D Allen
Transgenes as molecular probes for genomic imprinting.
Trends in genetics : TIG 1988;4(3):59-62.