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Jesús Cortés

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Orestis Lazos; Manuela Tosin; Adrian L Slusarczyk; Steven Boakes; Jesús Cortés; Philip J Sidebottom; Peter F Leadlay
Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters.
Laurenz Kellenberger; Ian S Galloway; Guido Sauter; Günter Böhm; U Hanefeld; Jesús Cortés; James Staunton; Peter F Leadlay
A polylinker approach to reductive loop swaps in modular polyketide synthases.
Steven Boakes; Markiyan Oliynyk; Jesús Cortés; Ines Böhm; Brian A M Rudd; W Peter Revill; James Staunton; Peter F Leadlay
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.

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All Publications

2010: Orestis Lazos; Manuela Tosin; Adrian L Slusarczyk; Steven Boakes; Jesús Cortés; Philip J Sidebottom; Peter F Leadlay
Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters.
Chemistry & biology 2010;17(2):160-73.
2008: Laurenz Kellenberger; Ian S Galloway; Guido Sauter; Günter Böhm; U Hanefeld; Jesús Cortés; James Staunton; Peter F Leadlay
A polylinker approach to reductive loop swaps in modular polyketide synthases.
Chembiochem : a European journal of chemical biology 2008;9(16):2740-9.
2004: Steven Boakes; Markiyan Oliynyk; Jesús Cortés; Ines Böhm; Brian A M Rudd; W Peter Revill; James Staunton; Peter F Leadlay
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.
Journal of molecular microbiology and biotechnology 2004;8(2):73-80.
2003: Francesca Del Vecchio; Hrvoje Petkovic; Steven G Kendrew; Lindsey Low; Barrie Wilkinson; Rachel E Lill; Jesús Cortés; Brian A M Rudd; James Staunton; Peter F Leadlay
Active-site residue, domain and module swaps in modular polyketide synthases.
Journal of industrial microbiology & biotechnology 2003;30(8):489-94.
2002: Jesús Cortés; Javier Velasco; Graham Foster; Andrew P Blackaby; Brian A M Rudd; Barrie Wilkinson
Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in Saccharopolyspora erythraea.
Molecular microbiology 2002;44(5):1213-24.
2002: Paul F Long; Christopher J Wilkinson; Christian P Bisang; Jesús Cortés; Nicholas Dunster; Markiyan Oliynyk; Ellen McCormick; Hamish McArthur; Carmen Mendez; José A Salas; James Staunton; Peter F Leadlay
Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase.
Molecular microbiology 2002;43(5):1215-25.
2002: Lars H Østergaard; Laurenz Kellenberger; Jesús Cortés; Marc P Roddis; Matthew Deacon; James Staunton; Peter F Leadlay
Stereochemistry of catalysis by the ketoreductase activity in the first extension module of the erythromycin polyketide synthase.
Biochemistry 2002;41(8):2719-26.
2001: Peter F Leadlay; James Staunton; Markiyan Oliynyk; Christian P Bisang; Jesús Cortés; EJ Frost; Zoë A Hughes-Thomas; Michelle A Jones; Steven G Kendrew; J B Lester; Paul F Long; Hamish McArthur; Ellen McCormick; Z Oliynyk; Christian B W Stark; Christopher J Wilkinson
Engineering of complex polyketide biosynthesis--insights from sequencing of the monensin biosynthetic gene cluster.
Journal of industrial microbiology & biotechnology 2001;27(6):360-7.
2000: Barrie Wilkinson; Graham Foster; Brian A M Rudd; NL Taylor; Andrew P Blackaby; Philip J Sidebottom; D J Cooper; Michael J Dawson; AD Buss; Sabine Gaisser; Ines Böhm; CJ Rowe; Jesús Cortés; Peter F Leadlay; James Staunton
Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase.
Chemistry & biology 2000;7(2):111-7.
1999: A Ranganathan; Máire C Timoney; Mark Bycroft; Jesús Cortés; Iain Thomas; Barrie Wilkinson; Laurenz Kellenberger; U Hanefeld; I S Galloway; James Staunton; Peter F Leadlay
Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues.
Chemistry & biology 1999;6(10):731-41.
1999: Christian P Bisang; Paul F Long; Jesús Cortés; James Westcott; John Crosby; Anne-Lise Matharu; Russell Cox; Thomas J Simpson; James Staunton; Peter F Leadlay
A chain initiation factor common to both modular and aromatic polyketide synthases.
Nature 1999;401(6752):502-5.
1998: CJ Rowe; Jesús Cortés; Sabine Gaisser; James Staunton; Peter F Leadlay
Construction of new vectors for high-level expression in actinomycetes.
Gene 1998;216(1):215-23.
1998: Ines Böhm; IE Holzbaur; U Hanefeld; Jesús Cortés; James Staunton; Peter F Leadlay
Engineering of a minimal modular polyketide synthase, and targeted alteration of the stereospecificity of polyketide chain extension.
Chemistry & biology 1998;5(8):407-12.
1998: Sabine Gaisser; G A Böhm; M Doumith; MC Raynal; N Dhillon; Jesús Cortés; Peter F Leadlay
Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.
Molecular & general genetics : MGG 1998;258(1-2):78-88.
1998: K Salah-Bey; M Doumith; JM Michel; Stephen F Haydock; Jesús Cortés; Peter F Leadlay; MC Raynal
Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea.
Molecular & general genetics : MGG 1998;257(5):542-53.
1998: A F Marsden; Barrie Wilkinson; Jesús Cortés; N J Dunster; James Staunton; Peter F Leadlay
Engineering broader specificity into an antibiotic-producing polyketide synthase.
Science (New York, N.Y.) 1998;279(5348):199-202.
1997: Sabine Gaisser; G A Böhm; Jesús Cortés; Peter F Leadlay
Analysis of seven genes from the eryAI-eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea.
Molecular & general genetics : MGG 1997;256(3):239-51.
1996: M Oliynyk; M J Brown; Jesús Cortés; James Staunton; Peter F Leadlay
A hybrid modular polyketide synthase obtained by domain swapping.
Chemistry & biology 1996;3(10):833-9.
1995: K E Wiesmann; Jesús Cortés; M J Brown; A L Cutter; James Staunton; Peter F Leadlay
Polyketide synthesis in vitro on a modular polyketide synthase.
Chemistry & biology 1995;2(9):583-9.
1995: T Schwecke; Jesus Aparicio; I Molnár; A König; L E Khaw; S F Haydock; M Oliynyk; P Caffrey; Jesús Cortés; J B Lester
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7839-43.