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Gerardo Corzo

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Figen Caliskan; Fredy I Coronas-Valderrama; Gerardo Corzo; Veronica Quintero-Hernández; Rita Restano-Cassulini; Lourival D Possani
Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Ligia Corrales-Garcia; Ernesto Ortiz; Bruno Rivas-Santiago; Julio Castañeda-Delgado; Gerardo Corzo
Bacterial expression and antibiotic activities of recombinant variants of human β-defensins on pathogenic bacteria and M. tuberculosis.
Francia Garcia; Jorge F Paniagua-Solis; Lourival D Possani; Alexis Rodriguez; Gabriel Sandoval-Lopez; Villegas Villarreal Elba Crsitina; Gerardo Pavel Espino-Solis; Gerardo Corzo
Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics.

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All Publications

2013: Figen Caliskan; Fredy I Coronas-Valderrama; Gerardo Corzo; Veronica Quintero-Hernández; Rita Restano-Cassulini; Lourival D Possani
Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Biochimie 2013;95(6):1216-22.
2013: Ligia Corrales-Garcia; Ernesto Ortiz; Bruno Rivas-Santiago; Julio Castañeda-Delgado; Gerardo Corzo
Bacterial expression and antibiotic activities of recombinant variants of human β-defensins on pathogenic bacteria and M. tuberculosis.
Protein expression and purification 2013;89(1):33-43.
2013: Francia Garcia; Jorge F Paniagua-Solis; Lourival D Possani; Alexis Rodriguez; Gabriel Sandoval-Lopez; Villegas Villarreal Elba Crsitina; Gerardo Pavel Espino-Solis; Gerardo Corzo
Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics.
The Journal of antibiotics 2013;66(1):3-10.
2012: Figen Caliskan; Fredy I V Coronas; Gerardo Corzo; Blanca Inés García; Ferhan Korkmaz; Rita Restano-Cassulini; Yalcin Sahin; Lourival D Possani
Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.
Peptides 2012;37(1):106-12.
2012: Santos Ramírez-Carreto; Lourival D Possani; Veronica Quintero-Hernández; Baltazar Becerril; Gerardo Corzo; Juana María Jiménez-Vargas; Ernesto Ortiz
Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae.
Peptides 2012;34(2):290-5.
2012: Alma L Saucedo; Federico del Rio-Portilla; Muriel DELEPIERRE; Georgina Estrada; Cristiana Picco; Lourival D Possani; Gianfranco Prestipino; Gerardo Corzo
Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 sodium channels.
Biochimica et biophysica acta 2012;1824(3):478-87.
2012: Emanuele Schiavon; Enzo Wanke; Gerardo Corzo; Georgina B Gurrola; Timoteo Olamendi-Portugal; Martha Pedraza-Escalona; Lourival D Possani
Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels.
Toxicon : official journal of the International Society on Toxinology 2012;59(2):283-93.
2011: Gerardo Pavel Espino-Solis; Georgina Estrada; Timoteo Olamendi-Portugal; Villegas Villarreal Elba Crsitina; Fernando Z Zamudio; Sandrine Cestele; Lourival D Possani; Gerardo Corzo
Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.
Toxicon : official journal of the International Society on Toxinology 2011;57(5):739-46.
2011: Georgina Estrada; Rita Restano-Cassulini; Ernesto Ortiz; Lourival D Possani; Gerardo Corzo
Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6.
Peptides 2011;32(1):75-9.
2011: L L Corrales-Garcia; Lourival D Possani; Gerardo Corzo
Expression systems of human β-defensins: vectors, purification and biological activities.
Amino acids 2011;40(1):5-13.
2011: A Rodríguez; Villegas Villarreal Elba Crsitina; H Satake; Lourival D Possani; Gerardo Corzo
Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index.
Amino acids 2011;40(1):61-8.
2009: Gerardo Corzo; Ada Prochnicka-Chalufour; Blanca I García; Lourival D Possani; Muriel DELEPIERRE
Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochimica et biophysica acta 2009;1794(11):1591-8.
2009: Kenya Hernández-Salgado; Georgina Estrada; Alejandro Olvera; Fredy I Coronas; Lourival D Possani; Gerardo Corzo
Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus.
Immunology letters 2009;125(2):93-9.
2009: Gerardo Corzo; Cedric Bernard; Herlinda Clement; Villegas Villarreal Elba Crsitina; Frank Bosmans; Jan Tytgat; Lourival D Possani; Herve Darbon; Alejandro Alagón
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochimica et biophysica acta 2009;1794(8):1190-6.
2008: Gerardo Corzo; Elia Diego-García; Herlinda Clement; Steve Peigneur; George Odell; Jan Tytgat; Lourival D Possani; Alejandro Alagón
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides 2008;29(11):1901-8.
2008: Gerardo Corzo; Ferenc Papp; Zoltan Varga; Omar Barraza; Pavel G Espino-Solis; Ricardo C Rodríguez de la Vega; Rezso Gaspar; Gyorgy Panyi; Lourival D Possani
A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus.
Biochemical pharmacology 2008;76(9):1142-54.
2007: Georgina Estrada; Blanca I Garcia; Emanuele Schiavon; Ernesto Ortiz; Sandrine Cestele; Enzo Wanke; Lourival D Possani; Gerardo Corzo
Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro.
Biochimica et biophysica acta 2007;1770(8):1161-8.
2007: Izhar Karbat; Roy Kahn; Lior Cohen; Nitza Ilan; Nicolas Gilles; Gerardo Corzo; Oren Froy; Maya Gur; Gudrun Albrecht; Stefan H Heinemann; Dalia Gordon; Michael Gurevitz
The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.
The FEBS journal 2007;274(8):1918-31.
2007: Gerardo Corzo; Jennifer K Sabo; Frank Bosmans; Bert Billen; Villegas Villarreal Elba Crsitina; Jan Tytgat; Raymond S Norton
Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels.
The Journal of biological chemistry 2007;282(7):4643-52.
2007: Georgina Estrada; Villegas Villarreal Elba Crsitina; Gerardo Corzo
Spider venoms: a rich source of acylpolyamines and peptides as new leads for CNS drugs.
Natural product reports 2007;24(1):145-61.
2007: Villegas Villarreal Elba Crsitina; Gerardo Corzo
Venomous drugs?
Molecular bioSystems 2007;3(1):B7.
2006: Kaoru Nomura; Gerardo Corzo
The effect of binding of spider-derived antimicrobial peptides, oxyopinins, on lipid membranes.
Biochimica et biophysica acta 2006;1758(9):1475-82.
2006: Ada Prochnicka-Chalufour; Gerardo Corzo; Honoo Satake; Marie-France Martin-Eauclaire; Anna Rosa Murgia; Gianfranco Prestipino; Gina D'Suze; Lourival D Possani; Muriel DELEPIERRE
Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry 2006;45(6):1795-804.
2005: Kaoru Nomura; Gilles Ferrat; Terumi Nakajima; Hervé Darbon; Takashi Iwashita; Gerardo Corzo
Induction of morphological changes in model lipid membranes and the mechanism of membrane disruption by a large scorpion-derived pore-forming peptide.
Biophysical journal 2005;89(6):4067-80.
2005: Benjamin Chagot; Cyril Pimentel; Li Dai; Joost Pil; Jan Tytgat; Terumi Nakajima; Gerardo Corzo; Hervé Darbon; Gilles Ferrat
An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis.
The Biochemical journal 2005;388(Pt 1):263-71.
2005: Gilles Ferrat; Frank Bosmans; Jan Tytgat; Cyril Pimentel; Benjamin Chagot; Nicolas Gilles; Terumi Nakajima; Hervé Darbon; Gerardo Corzo
Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na+ channel.
Proteins 2005;59(2):368-79.
2005: Gerardo Corzo; pierre escoubas; Villegas Villarreal Elba Crsitina; Izhar Karbat; Dalia Gordon; Michael Gurevitz; Terumi Nakajima; Nicolas Gilles
A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels.
Biochemistry 2005;44(5):1542-9.
2004: Kaoru Nomura; Gerardo Corzo; Terumi Nakajima; Takashi Iwashita
Orientation and pore-forming mechanism of a scorpion pore-forming peptide bound to magnetically oriented lipid bilayers.
Biophysical journal 2004;87(4):2497-507.
2004: Olga S Belokoneva; Honoo Satake; Elena L Mal'tseva; Nadezhda P Pal'mina; Villegas Villarreal Elba Crsitina; Terumi Nakajima; Gerardo Corzo
Pore formation of phospholipid membranes by the action of two hemolytic arachnid peptides of different size.
Biochimica et biophysica acta 2004;1664(2):182-8.
2004: Honoo Satake; Villegas Villarreal Elba Crsitina; Naomasa Oshiro; K Terada; Tetsuro Shinada; Gerardo Corzo
Rapid and efficient identification of cysteine-rich peptides by random screening of a venom gland cDNA library from the hexathelid spider Macrothele gigas.
Toxicon : official journal of the International Society on Toxinology 2004;44(2):149-56.
2004: Benjamin Chagot; pierre escoubas; Villegas Villarreal Elba Crsitina; Cédric Bernard; Gilles Ferrat; Gerardo Corzo; Michel Lazdunski; Hervé Darbon
Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus.
Protein science : a publication of the Protein Society 2004;13(5):1197-208.
2004: Lior Cohen; Izhar Karbat; Nicolas Gilles; Oren Froy; Gerardo Corzo; Ruthie Angelovici; Dalia Gordon; Michael Gurevitz
Dissection of the functional surface of an anti-insect excitatory toxin illuminates a putative "hot spot" common to all scorpion beta-toxins affecting Na+ channels.
The Journal of biological chemistry 2004;279(9):8206-11.
2004: Cédric Bernard; Gerardo Corzo; Satomi Adachi-Akahane; Guillaume Foures; Kazunori Kanemaru; Yasuo Furukawa; Terumi Nakajima; Hervé Darbon
Solution structure of ADO1, a toxin extracted from the saliva of the assassin bug, Agriosphodrus dohrni.
Proteins 2004;54(2):195-205.
2003: Gerardo Corzo; pierre escoubas
Pharmacologically active spider peptide toxins.
Cellular and molecular life sciences : CMLS 2003;60(11):2409-26.
2003: Olga S Belokoneva; Villegas Villarreal Elba Crsitina; Gerardo Corzo; Li Dai; Terumi Nakajima
The hemolytic activity of six arachnid cationic peptides is affected by the phosphatidylcholine-to-sphingomyelin ratio in lipid bilayers.
Biochimica et biophysica acta 2003;1617(1-2):22-30.
2003: Gerardo Corzo; Nicolas Gilles; Honoo Satake; Villegas Villarreal Elba Crsitina; Li Dai; Terumi Nakajima; Joachim Haupt
Distinct primary structures of the major peptide toxins from the venom of the spider Macrothele gigas that bind to sites 3 and 4 in the sodium channel.
FEBS letters 2003;547(1-3):43-50.
2003: Tetsuro Shinada; Y Nakagawa; K Hayashi; Gerardo Corzo; Terumi Nakajima; Yasufumi Ohfune
Synthesis and paralytic activities of squaryl amino acid-containing polyamine toxins.
Amino acids 2003;24(3):293-301.
2002: Gerardo Corzo; Villegas Villarreal Elba Crsitina; Froylan Gómez-Lagunas; Lourival D Possani; Olga S Belokoneva; Terumi Nakajima
Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins.
The Journal of biological chemistry 2002;277(26):23627-37.
2002: pierre escoubas; Gerardo Corzo; Brian J Whiteley; Marie-Louise Célérier; Terumi Nakajima
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and high-performance liquid chromatography study of quantitative and qualitative variation in tarantula spider venoms.
Rapid communications in mass spectrometry : RCM 2002;16(5):403-13.
2001: Cédric Bernard; Gerardo Corzo; Amor Mosbah; Terumi Nakajima; Hervé Darbon
Solution structure of Ptu1, a toxin from the assassin bug Peirates turpis that blocks the voltage-sensitive calcium channel N-type.
Biochemistry 2001;40(43):12795-800.
2001: Gerardo Corzo; pierre escoubas; Villegas Villarreal Elba Crsitina; Kevin J Barnham; W He; R S Norton; Terumi Nakajima
Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator.
The Biochemical journal 2001;359(Pt 1):35-45.
2001: Gerardo Corzo; Satomi Adachi-Akahane; T Nagao; Y Kusui; Terumi Nakajima
Novel peptides from assassin bugs (Hemiptera: Reduviidae): isolation, chemical and biological characterization.
FEBS letters 2001;499(3):256-61.
2000: pierre escoubas; Sylvie Diochot; Gerardo Corzo
Structure and pharmacology of spider venom neurotoxins.
Biochimie 2000;82(9-10):893-907.
2000: Gerardo Corzo; pierre escoubas; Maria Stankiewicz; Marcel Pelhate; C P Kristensen; Terumi Nakajima
Isolation, synthesis and pharmacological characterization of delta-palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae).
European journal of biochemistry / FEBS 2000;267(18):5783-95.
1999: pierre escoubas; J Chamot-Rooke; Reto Stöcklin; B J Whiteley; Gerardo Corzo; R Genet; Terumi Nakajima
A comparison of matrix-assisted laser desorption/ionization time-of-flight and liquid chromatography electrospray ionization mass spectrometry methods for the analysis of crude tarantula venoms in the Pterinochilus group.
Rapid communications in mass spectrometry : RCM 1999;13(18):1861-8.