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David Cosman

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Padmaja Paidipally; Sivakumar Periasamy; Peter F Barnes; Rohan Dhiman; Mohanalaxmi Indramohan; David E Griffith; David Cosman; Ramakrishna Vankayalapati
NKG2D-dependent IL-17 production by human T cells in response to an intracellular pathogen.
Sugata Roy; Peter F Barnes; Ankita Garg; Shiping Wu; David Cosman; Ramakrishna Vankayalapati
NK cells lyse T regulatory cells that expand in response to an intracellular pathogen.
Claudia S Wagner; Alexander Rölle; David Cosman; Hans-Gustaf Ljunggren; Kurt D Berndt; Adnane Achour
Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1.

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2009: Padmaja Paidipally; Sivakumar Periasamy; Peter F Barnes; Rohan Dhiman; Mohanalaxmi Indramohan; David E Griffith; David Cosman; Ramakrishna Vankayalapati
NKG2D-dependent IL-17 production by human T cells in response to an intracellular pathogen.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):1940-5.
2008: Sugata Roy; Peter F Barnes; Ankita Garg; Shiping Wu; David Cosman; Ramakrishna Vankayalapati
NK cells lyse T regulatory cells that expand in response to an intracellular pathogen.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1729-36.
2007: Claudia S Wagner; Alexander Rölle; David Cosman; Hans-Gustaf Ljunggren; Kurt D Berndt; Adnane Achour
Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1.
Journal of molecular biology 2007;373(3):695-705.
2007: Cristina Cerboni; Francesca Neri; Nicoletta Casartelli; Alessandra Zingoni; David Cosman; Paolo Rossi; Angela Santoni; Margherita Doria
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity.
The Journal of general virology 2007;88(Pt 1):242-50.
2006: Claire L Sutherland; Brian A Rabinovich; N Jan Chalupny; Pierre Brawand; Robert Miller; David Cosman
ULBPs, human ligands of the NKG2D receptor, stimulate tumor immunity with enhancement by IL-15.
Blood 2006;108(4):1313-9.
2006: N Jan Chalupny; Annie Rein-Weston; Stephanie Dosch; David Cosman
Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142.
Biochemical and biophysical research communications 2006;346(1):175-81.
2006: Brian A Rabinovich; Jennifer Li; Martin Wolfson; William Lawrence; Courtney Beers; Jan Chalupny; Rose Hurren; Brad Greenfield; Richard Miller; David Cosman
NKG2D splice variants: a reexamination of adaptor molecule associations.
Immunogenetics 2006;58(2-3):81-8.
2006: Cristina Cerboni; Adnane Achour; Anette Wärnmark; Mehrdad Mousavi-Jazi; Tatyana Sandalova; Mei-Ling Hsu; David Cosman; Klas Kärre; Ennio Carbone
Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j.
European journal of immunology 2006;36(3):732-41.
2005: Ramakrishna Vankayalapati; Ankita Garg; Angel Porgador; David E Griffith; Peter Klucar; Hassan Safi; William M Girard; David Cosman; Thomas Spies; Peter F Barnes
Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4611-7.
2005: Jennifer Li; Brian A Rabinovich; Rose Hurren; David Cosman; Richard G Miller
Survival versus neglect: redefining thymocyte subsets based on expression of NKG2D ligand(s) and MHC class I.
European journal of immunology 2005;35(2):439-48.
2005: Ennio Carbone; Paola Neri; Maria Mesuraca; Mariateresa Fulciniti; Takemi Otsuki; Daniela Pende; Veronika Groh; Thomas Spies; Giuditta Pollio; David Cosman; Lucio Catalano; Pierfrancesco Tassone; Bruno Rotoli; Salvatore Venuta
HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells.
Blood 2005;105(1):251-8.
2004: Konstantina Eleme; Sabrina B Taner; Björn Onfelt; Lucy M Collinson; Fiona E McCann; N Jan Chalupny; David Cosman; Colin Hopkins; Anthony I Magee; Daniel M Davis
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.
The Journal of experimental medicine 2004;199(7):1005-10.
2003: Alexander Rölle; Mehrdad Mousavi-Jazi; Mikael Eriksson; Jacob Odeberg; Cecilia Söderberg-Nauclér; David Cosman; Klas Kärre; Cristina Cerboni
Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):902-8.
2003: Claire Dunn; N Jan Chalupny; Claire L Sutherland; Stephanie Dosch; P V Sivakumar; David C Johnson; David Cosman
Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity.
The Journal of experimental medicine 2003;197(11):1427-39.
2003: N Jan Chalupny; Claire L Sutherland; William A Lawrence; Annie Rein-Weston; David Cosman
ULBP4 is a novel ligand for human NKG2D.
Biochemical and biophysical research communications 2003;305(1):129-35.
2003: Jennifer Wu; N Jan Chalupny; Thomas J Manley; Stanley R Riddell; David Cosman; Thomas Spies
Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(8):4196-200.
2003: Jacob Odeberg; Helena Browne; Sunil S Metkar; Christopher J Froelich; Lars Brandén; David Cosman; Cecilia Söderberg-Nauclér
The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins.
Journal of virology 2003;77(8):4539-45.
2003: Brian A Rabinovich; Jennifer Li; John Shannon; Rose Hurren; Jan Chalupny; David Cosman; Richard G Miller
Activated, but not resting, T cells can be recognized and killed by syngeneic NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3572-6.
2003: Louise Berg; Gerdt C Riise; David Cosman; Tomas Bergström; Sigvard Olofsson; Klas Kärre; Ennio Carbone
LIR-1 expression on lymphocytes, and cytomegalovirus disease in lung-transplant recipients.
Lancet 2003;361(9363):1099-101.
2003: Nicodemus Tedla; Christianne Bandeira-Melo; Paolo Tassinari; David E Sloane; Mary Samplaski; David Cosman; Luis Borges; Peter Weller; Jonathan P Arm
Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1174-9.
2002: Allison P Armstrong; Mark E Tometsko; Moira Glaccum; Claire L Sutherland; David Cosman; William C Dougall
A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function.
The Journal of biological chemistry 2002;277(46):44347-56.
2002: Daniela Pende; Paola Rivera; Stefania Marcenaro; Chien-Chung Chang; Roberto Biassoni; Romana Conte; Marek Kubin; David Cosman; Soldano Ferrone; Lorenzo Moretta; Alessandro Moretta
Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity.
Cancer research 2002;62(21):6178-86.
2002: Nicodemus Tedla; Kathryn Gibson; H Patrick McNeil; David Cosman; Luis Borges; Jonathan P Arm
The co-expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium.
The American journal of pathology 2002;160(2):425-31.
2002: Claire L Sutherland; N Jan Chalupny; Kenneth Schooley; Tim VandenBos; Marek Kubin; David Cosman
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):671-9.
2001: Claire L Sutherland; N Jan Chalupny; David Cosman
The UL16-binding proteins, a novel family of MHC class I-related ligands for NKG2D, activate natural killer cell functions.
Immunological reviews 2001;181():185-92.
2001: Marek Kubin; L Cassiano; Jan Chalupny; W Chin; David Cosman; WC Fanslow; J Müllberg; A M Rousseau; D Ulrich; Richard J Armitage
ULBP1, 2, 3: novel MHC class I-related molecules that bind to human cytomegalovirus glycoprotein UL16, activate NK cells.
European journal of immunology 2001;31(5):1428-37.
2001: David Cosman; J Müllberg; Claire L Sutherland; W Chin; Richard J Armitage; WC Fanslow; Marek Kubin; N Jan Chalupny
ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.
Immunity 2001;14(2):123-33.
2000: L Borges; David Cosman
LIRs/ILTs/MIRs, inhibitory and stimulatory Ig-superfamily receptors expressed in myeloid and lymphoid cells.
Cytokine & growth factor reviews 2000;11(3):209-17.
1999: William C Dougall; Moira Glaccum; Keith Charrier; K Rohrbach; Kenneth Brasel; Thibaut De Smedt; Elizabeth Daro; J Smith; Mark E Tometsko; Charles R Maliszewski; Allison Armstrong; V Shen; S Bain; David Cosman; D Anderson; P J Morrissey; Jacques J Peschon; JoAnn C L Schuh
RANK is essential for osteoclast and lymph node development.
Genes & development 1999;13(18):2412-24.
1999: NA Fanger; Luis Borges; David Cosman
The leukocyte immunoglobulin-like receptors (LIRs): a new family of immune regulators.
Journal of leukocyte biology 1999;66(2):231-6.
1999: Lisa M Sedger; D M Shows; R A Blanton; Jacques J Peschon; R G Goodwin; David Cosman; S R Wiley
IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):920-6.
1999: David Cosman; NA Fanger; Luis Borges
Human cytomegalovirus, MHC class I and inhibitory signalling receptors: more questions than answers.
Immunological reviews 1999;168():177-85.
1999: J Müllberg; Mei-Ling Hsu; Charles T Rauch; Mary J Gerhart; A Kaykas; David Cosman
The R27080 glycoprotein is abundantly secreted from human cytomegalovirus-infected fibroblasts.
The Journal of general virology 1999;80 ( Pt 2)():437-40.
1999: Luis Borges; NA Fanger; David Cosman
Interactions of LIRs, a family of immunoreceptors expressed in myeloid and lymphoid cells, with viral and cellular MHC class I antigens.
Current topics in microbiology and immunology 1999;244():123-36.
1999: Massimo Vitale; Roberta Castriconi; Silvia Parolini; Daniela Pende; Mei-Ling Hsu; Lorenzo Moretta; David Cosman; Alessandro Moretta
The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones.
International immunology 1999;11(1):29-35.
1998: L Galibert; Mark E Tometsko; D M Anderson; David Cosman; William C Dougall
The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily.
The Journal of biological chemistry 1998;273(51):34120-7.
1998: NA Fanger; David Cosman; L Peterson; S C Braddy; Charles R Maliszewski; Luis Borges
The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes.
European journal of immunology 1998;28(11):3423-34.
1997: Luis Borges; Mei-Ling Hsu; NA Fanger; Marek Kubin; David Cosman
A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5192-6.
1997: D M Anderson; Eugene Maraskovsky; W L Billingsley; William C Dougall; Mark E Tometsko; E R Roux; Mark Teepe; RF DuBose; David Cosman; L Galibert
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
Nature 1997;390(6656):175-9.
1997: David Cosman; NA Fanger; Luis Borges; Marek Kubin; W Chin; L Peterson; Mei-Ling Hsu
A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules.
Immunity 1997;7(2):273-82.
1997: J Müllberg; Charles T Rauch; Martin F Wolfson; Beverly J Castner; JN Fitzner; C Otten-Evans; Ken Mohler; David Cosman; Roy A Black
Further evidence for a common mechanism for shedding of cell surface proteins.
FEBS letters 1997;401(2-3):235-8.
1996: B Mosley; C De Imus; D Friend; Norman Boiani; B Thoma; L S Park; David Cosman
Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.
The Journal of biological chemistry 1996;271(51):32635-43.
1996: N Kumaki; D M Anderson; David Cosman; Satoru Kumaki
Expression of interleukin-15 and its receptor by human fetal retinal pigment epithelial cells.
Current eye research 1996;15(8):876-82.
1996: Satoru Kumaki; R Armitage; M Ahdieh; L Park; David Cosman
Interleukin-15 up-regulates interleukin-2 receptor alpha chain but down-regulates its own high-affinity binding sites on human T and B cells.
European journal of immunology 1996;26(6):1235-9.
1995: J Müllberg; F H Durie; C Otten-Evans; M R Alderson; S Rose-John; David Cosman; Roy A Black; K M Mohler
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5198-205.
1995: Satoru Kumaki; Hans D Ochs; M Timour; Kenneth Schooley; M Ahdieh; H Hill; K Sugamura; D Anderson; Q Zhu; David Cosman
Characterization of B-cell lines established from two X-linked severe combined immunodeficiency patients: interleukin-15 binds to the B cells but is not internalized efficiently.
Blood 1995;86(4):1428-36.
1995: Judith Goldstein Giri; Satoru Kumaki; M Ahdieh; D J Friend; A Loomis; K Shanebeck; R DuBose; David Cosman; L S Park; D M Anderson
Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor.
The EMBO journal 1995;14(15):3654-63.
1995: Judith Goldstein Giri; D M Anderson; Satoru Kumaki; L S Park; Kenneth H Grabstein; David Cosman
IL-15, a novel T cell growth factor that shares activities and receptor components with IL-2.
Journal of leukocyte biology 1995;57(5):763-6.
1995: S E Ziegler; K K Morella; D Anderson; N Kumaki; Warren J Leonard; David Cosman; H Baumann
Reconstitution of a functional interleukin (IL)-7 receptor demonstrates that the IL-2 receptor gamma chain is required for IL-7 signal transduction.
European journal of immunology 1995;25(2):399-404.
1995: Najet Debili; Françoise Wendling; David Cosman; Monique Titeux; C Florindo; Isabelle Dusanter-Fourt; Kenneth Schooley; N Methia; M Charon; R Nador
The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets.
Blood 1995;85(2):391-401.
1995: David Cosman; Satoru Kumaki; M Ahdieh; J Eisenman; Kenneth H Grabstein; R Paxton; R DuBose; D Friend; L S Park; D Anderson
Interleukin 15 and its receptor.
Ciba Foundation symposium 1995;195():221-9; discussion 229-33.
1994: David Cosman
A family of ligands for the TNF receptor superfamily.
Stem cells (Dayton, Ohio) 1994;12(5):440-55.
1994: Françoise Wendling; Eugene Maraskovsky; Najet Debili; C Florindo; Mark Teepe; Monique Titeux; N Methia; J Breton-Gorius; David Cosman; William Vainchenker
cMpl ligand is a humoral regulator of megakaryocytopoiesis.
Nature 1994;369(6481):571-4.
1994: Judith Goldstein Giri; M Ahdieh; J Eisenman; K Shanebeck; Kenneth H Grabstein; Satoru Kumaki; A Namen; L S Park; David Cosman; D Anderson
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.
The EMBO journal 1994;13(12):2822-30.
1994: D P Gearing; Steven F Ziegler; M R Comeau; D Friend; B Thoma; David Cosman; L Park; B Mosley
Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):1119-23.
1993: R B Gayle; K Poindexter; David Cosman; Steven K Dower; S Gillis; T Hopp; R Jerzy; S Kronheim; V Lum; A Lewis
Identification of regions in interleukin-1 alpha important for activity.
The Journal of biological chemistry 1993;268(29):22105-11.
1993: I Vigon; C Florindo; Serge Fichelson; J L Guenet; M G Mattei; M Souyri; David Cosman; Sylvie Gisselbrecht
Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth.
Oncogene 1993;8(10):2607-15.
1993: David Cosman
The hematopoietin receptor superfamily.
Cytokine 1993;5(2):95-106.
1992: L S Park; U Martin; R Sorensen; S Luhr; PJ Morrissey; David Cosman; A Larsen
Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complex.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4295-9.
1992: Melanie Spriggs; P J Nevens; K Grabstein; S K Dower; David Cosman; Richard J Armitage; C J McMahan; John E Sims
Molecular characterization of the interleukin-1 receptor (IL-1R) on monocytes and polymorphonuclear cells.
Cytokine 1992;4(2):90-5.
1991: D P Gearing; C J Thut; T VandeBos; S D Gimpel; P B Delaney; J King; V Price; David Cosman; M P Beckmann
Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.
The EMBO journal 1991;10(10):2839-48.
1991: C J McMahan; JL Slack; B Mosley; David Cosman; S D Lupton; L L Brunton; C E Grubin; J M Wignall; N A Jenkins; C I Brannan
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.
The EMBO journal 1991;10(10):2821-32.
1991: D M Anderson; D E Williams; R Tushinski; S Gimpel; J Eisenman; Linda Cannizzaro; M Aronson; C M Croce; K Huebner; David Cosman
Alternate splicing of mRNAs encoding human mast cell growth factor and localization of the gene to chromosome 12q22-q24.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(8):373-8.
1990: Melanie Spriggs; P J Lioubin; J Slack; Steven K Dower; U Jonas; David Cosman; John E Sims; J Bauer
Induction of an interleukin-1 receptor (IL-1R) on monocytic cells. Evidence that the receptor is not encoded by a T cell-type IL-1R mRNA.
The Journal of biological chemistry 1990;265(36):22499-505.
1990: A Larsen; T Davis; B M Curtis; S Gimpel; John E Sims; David Cosman; L Park; E Sorensen; CJ March; CA Smith
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
The Journal of experimental medicine 1990;172(6):1559-70.
1990: D M Anderson; S D Lyman; A Baird; J M Wignall; J Eisenman; Charles T Rauch; CJ March; H Scott Boswell; S D Gimpel; David Cosman
Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms.
Cell 1990;63(1):235-43.
1990: CA Smith; T Davis; D Anderson; L Solam; M P Beckmann; R Jerzy; Steven K Dower; David Cosman; RG Goodwin
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins.
Science (New York, N.Y.) 1990;248(4958):1019-23.
1990: S D Lupton; S Gimpel; R Jerzy; L L Brunton; K A Hjerrild; David Cosman; RG Goodwin
Characterization of the human and murine IL-7 genes.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3592-601.
1990: RG Goodwin; D Friend; Steven F Ziegler; R Jerzy; B A Falk; S Gimpel; David Cosman; Steven K Dower; CJ March; A E Namen
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
Cell 1990;60(6):941-51.
1990: Douglas Pat Cerretti; J Wignall; D Anderson; R J Tushinski; Byron Gallis; David Cosman
Membrane bound forms of human macrophage colony stimulating factor (M-CSF, CSF-1).
Progress in clinical and biological research 1990;352():63-70.
1989: Bruce R Blazar; M B Widmer; David Cosman; H M Sassenfeld; DA Vallera
Improved survival and leukocyte reconstitution without detrimental effects on engraftment in murine recipients of human recombinant granulocyte colony-stimulating factor after transplantation of T-cell-depleted histoincompatible bone marrow.
Blood 1989;74(6):2264-9.
1989: P J Conlon; PJ Morrissey; R P Nordan; Kenneth H Grabstein; K S Prickett; Steven G Reed; R Goodwin; David Cosman; A E Namen
Murine thymocytes proliferate in direct response to interleukin-7.
Blood 1989;74(4):1368-73.
1989: L S Park; P E Waldron; D Friend; H M Sassenfeld; V Price; D Anderson; David Cosman; R G Andrews; Irwin D Bernstein; D L Urdal
Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: receptor heterogeneity and relationship to growth factor responsiveness.
Blood 1989;74(1):56-65.
1989: Steven K Dower; J M Wignall; Kenneth Schooley; C J McMahan; J L Jackson; K S Prickett; S Lupton; David Cosman; John E Sims
Retention of ligand binding activity by the extracellular domain of the IL-1 receptor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(12):4314-20.
1989: PJ Morrissey; RG Goodwin; R P Nordan; D Anderson; Kenneth H Grabstein; David Cosman; J Sims; S Lupton; B Acres; S G Reed
Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells.
The Journal of experimental medicine 1989;169(3):707-16.
1989: RG Goodwin; S Lupton; A Schmierer; K J Hjerrild; R Jerzy; W Clevenger; S Gillis; David Cosman; A E Namen
Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(1):302-6.
1989: D L Urdal; V Price; H M Sassenfeld; David Cosman; S Gillis; L S Park
Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3.
Annals of the New York Academy of Sciences 1989;554():167-76.
1988: Charles R Maliszewski; MA Schoenborn; Douglas Pat Cerretti; J M Wignall; K S Picha; David Cosman; R J Tushinski; S Gillis; P E Baker
Bovine GM-CSF: molecular cloning and biological activity of the recombinant protein.
Molecular immunology 1988;25(9):843-50.
1988: R T Libby; David Cosman; M K Cooney; J E Merriam; CJ March; T P Hopp
Human rhinovirus 3C protease: cloning and expression of an active form in Escherichia coli.
Biochemistry 1988;27(17):6262-8.
1988: David Cosman; J Wignall; D Anderson; J Tushinski; Byron Gallis; D Urdal; Douglas Pat Cerretti
Human macrophage colony stimulating factor (M-CSF): alternate RNA splicing generates three different proteins that are expressed on the cell surface and secreted.
Behring Institute Mitteilungen 1988;(83):15-26.
1988: S Gillis; D L Urdal; W Clevenger; R Klinke; H Sassenfeld; V Price; David Cosman
Production of recombinant human colony stimulating factors in yeast.
Behring Institute Mitteilungen 1988;(83):1-7.
1988: Douglas Pat Cerretti; J Wignall; D Anderson; R J Tushinski; Byron Gallis; M Stya; S Gillis; D L Urdal; David Cosman
Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene.
Molecular immunology 1988;25(8):761-70.
1988: John E Sims; CJ March; David Cosman; M B Widmer; H R MacDonald; C J McMahan; C E Grubin; J M Wignall; J L Jackson; S M Call
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily.
Science (New York, N.Y.) 1988;241(4865):585-9.
1988: Roy A Black; S R Kronheim; M Cantrell; M C Deeley; CJ March; K S Prickett; J Wignall; P J Conlon; David Cosman; T P Hopp
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.
The Journal of biological chemistry 1988;263(19):9437-42.
1988: Charles R Maliszewski; P E Baker; MA Schoenborn; B S Davis; David Cosman; S Gillis; Douglas Pat Cerretti
Cloning, sequence and expression of bovine interleukin 1 alpha and interleukin 1 beta complementary DNAs.
Molecular immunology 1988;25(5):429-37.
1988: R W Overell; K E Weisser; David Cosman
Stably transmitted triple-promoter retroviral vectors and their use in transformation of primary mammalian cells.
Molecular and cellular biology 1988;8(4):1803-8.
1988: David Cosman; M C Deeley; V Price; R Klinke; W Clevenger; T Hemenway; D Anderson; H Sassenfeld; D L Urdal
Human interleukin-3 and granulocyte-macrophage colony stimulating factor: site-specific mutagenesis and expression in yeast.
Developments in biological standardization 1988;69():9-13.
1987: R W Overell; J D Watson; Byron Gallis; K E Weisser; David Cosman; M B Widmer
Nature and specificity of lymphokine independence induced by a selectable retroviral vector expressing v-src.
Molecular and cellular biology 1987;7(10):3394-401.
1987: R T Libby; G Braedt; S R Kronheim; CJ March; D L Urdal; T A Chiaverotti; R J Tushinski; D Y Mochizuki; T P Hopp; David Cosman
Expression and purification of native human granulocyte-macrophage colony-stimulating factor from an Escherichia coli secretion vector.
DNA (Mary Ann Liebert, Inc.) 1987;6(3):221-9.
1987: B Mosley; D L Urdal; K S Prickett; A Larsen; David Cosman; P J Conlon; S Gillis; Steven K Dower
The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.
The Journal of biological chemistry 1987;262(7):2941-4.
1987: V Price; D Mochizuki; CJ March; David Cosman; M C Deeley; R Klinke; W Clevenger; S Gillis; P Baker; D Urdal
Expression, purification and characterization of recombinant murine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast.
Gene 1987;55(2-3):287-93.
1987: Steven K Dower; B Mosley; P J Conlon; P Benson; C Grubin; A Larsen; S Gillis; David Cosman
Molecular modification of lymphokines by in vitro mutagenesis.
Annals of the New York Academy of Sciences 1987;507():22-31.
1986: David Cosman; J Wignall; A Lewis; A Alpert; Douglas Pat Cerretti; L Park; S K Dower; S Gillis; D L Urdal
High level stable expression of human interleukin-2 receptors in mouse cells generates only low affinity interleukin-2 binding sites.
Molecular immunology 1986;23(9):935-41.
1986: D P Cerretti; K McKereghan; A Larsen; David Cosman; S Gillis; P E Baker
Cloning, sequence, and expression of bovine interferon-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(12):4561-4.
1986: S Gillis; P J Conlon; David Cosman; T P Hopp; Steven K Dower; V Price; D Y Mochizuki; D L Urdal
Lymphokines: from conjecture to the clinic.
Seminars in oncology 1986;13(2):218-27.
1986: Douglas Pat Cerretti; K McKereghan; A Larsen; M A Cantrell; D Anderson; S Gillis; David Cosman; P E Baker
Cloning, sequence, and expression of bovine interleukin 2.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3223-7.
1986: Byron Gallis; A Lewis; J Wignall; A Alpert; D Y Mochizuki; David Cosman; T Hopp; D Urdal
Phosphorylation of the human interleukin-2 receptor and a synthetic peptide identical to its C-terminal, cytoplasmic domain.
The Journal of biological chemistry 1986;261(11):5075-80.
1986: Kenneth H Grabstein; D Mochizuki; S Kronheim; V Price; David Cosman; D Urdal; S Gillis; P Conlon
Regulation of antibody production in vitro by granulocyte-macrophage colony stimulating factor.
The Journal of molecular and cellular immunology : JMCI 1986;2(4):199-207.
1984: David Cosman; Douglas Pat Cerretti; A Larsen; L Park; C March; S Dower; S Gillis; D Urdal
Cloning, sequence and expression of human interleukin-2 receptor.
Nature 1984;312(5996):768-71.