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François-Loïc Cosset

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Laetitia Zona; Amy Barnes; Laurent Brino; François-Loïc Cosset; François H T Duong; Sarah C Durand; Jonathan Florentin; Helen J Harris; Markus H Heim; Ivan Hirsch; François Le Naour; Joachim Lupberger; Jane A McKeating; Didier Samuel; Nazha Sidahmed-Adrar; Rajiv G Tawar; Christine Thumann; Marine Turek; Fei Xiao; Mirjam B Zeisel; Thomas F Baumert
HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.
Martine Tomkowiak; Els Verhoeyen; Didier Nègre; Judit Szécsi; Marie Teixeira; Jean-Louis Thoumas; Denise Aubert; Bariza Blanquier; Molly Brunner; François-Loïc Cosset; Charles-Antoine Coupet; Raffaella Ghittoni; Yann Leverrier; jacqueline marvel
Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.
Aurélie Ploquin; Judit Szécsi; Kum Thong Wong; Véronique Barateau; François-Loïc Cosset; Vanessa Guillaume; Branka Horvat; Cyrille Mathieu; Kien Chai Ong; Anna Salvetti
Protection against henipavirus infection by use of recombinant adeno-associated virus-vector vaccines.

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2013: Laetitia Zona; Amy Barnes; Laurent Brino; François-Loïc Cosset; François H T Duong; Sarah C Durand; Jonathan Florentin; Helen J Harris; Markus H Heim; Ivan Hirsch; François Le Naour; Joachim Lupberger; Jane A McKeating; Didier Samuel; Nazha Sidahmed-Adrar; Rajiv G Tawar; Christine Thumann; Marine Turek; Fei Xiao; Mirjam B Zeisel; Thomas F Baumert
HRas signal transduction promotes hepatitis C virus cell entry by triggering assembly of the host tetraspanin receptor complex.
Cell host & microbe 2013;13(3):302-13.
2013: Martine Tomkowiak; Els Verhoeyen; Didier Nègre; Judit Szécsi; Marie Teixeira; Jean-Louis Thoumas; Denise Aubert; Bariza Blanquier; Molly Brunner; François-Loïc Cosset; Charles-Antoine Coupet; Raffaella Ghittoni; Yann Leverrier; jacqueline marvel
Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.
Genesis (New York, N.Y. : 2000) 2013;51(3):193-200.
2013: Aurélie Ploquin; Judit Szécsi; Kum Thong Wong; Véronique Barateau; François-Loïc Cosset; Vanessa Guillaume; Branka Horvat; Cyrille Mathieu; Kien Chai Ong; Anna Salvetti
Protection against henipavirus infection by use of recombinant adeno-associated virus-vector vaccines.
The Journal of infectious diseases 2013;207(3):469-78.
2013: Muhammad N Zahid; Viet Loan Dao Thi; Philippe Bachellier; Dorothea Bankwitz; Thomas F Baumert; François-Loïc Cosset; Leen Delang; Marlène Dreux; Isabel Fofana; Fritz Grunert; Maryse Guérin; Johan Neyts; Thomas Pietschmann; John Thompson; Marine Turek; Fei Xiao; Mirjam B Zeisel
The postbinding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination.
Hepatology (Baltimore, Md.) 2013;57(2):492-504.
2013: Patrycja J Lech; Claude P Muller; Rebecca Nace; Linh D Pham; Stephen J Russell; Gregory J Tobin; Els Verhoeyen; Ruth Bushnell; François-Loïc Cosset; Emily Gutschenritter; Peter L Nara
Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.
PloS one 2013;8(1):e52306.
2012: Viet Loan Dao Thi; Ralf Bartenschlager; Thomas F Baumert; François-Loïc Cosset; Christelle Granier; Ophélia Granio; Maryse Guérin; Dimitri Lavillette; Jimmy Mancip; François Penin; Mirjam B Zeisel; Marlène Dreux
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
The Journal of biological chemistry 2012;287(37):31242-57.
2012: Camille Lévy; Claude P Muller; Fouzia Amirache; Robin Buckland; François-Loïc Cosset; Caroline Costa; Cecilia Frecha; Hasan Kweder; Els Verhoeyen
Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(9):1699-712.
2012: Isabel Fofana; Steven K H Foung; F Habersetzer; Juliette Hayer; Laura Heydmann; Marie-Sophie Hiet; Zhen-Yong Keck; Thomas Pietschmann; Françoise Stoll-Keller; Marine Turek; Muhammad Nauman Zahid; Mirjam B Zeisel; Patric Carolla; Christophe Combet; François-Loïc Cosset; Karine Cury; Michel Doffoël; Samira Fafi-Kremer; Catherine Fauvelle; Ralf Bartenschlager; Thomas F Baumert
Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies.
Gastroenterology 2012;143(1):223-233.e9.
2012: Els Verhoeyen; Roger Le Grand; Francis Relouzat; Marie Cambot; François-Loïc Cosset; Caroline Costa; Anne Dubart Kupperschmitt; Christophe Joubert; Philippe Leboulch; Faézeh Legrand; Didier Nègre; Stephane Prost
Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.
Human gene therapy 2012;23(7):754-68.
2012: M Schoenhals; Els Verhoeyen; Jean-Luc Veyrune; Jérôme Moreaux; A Bruyer; A Caraux; François-Loïc Cosset; Cecilia Frecha; Michel Jourdan; Bernard Klein
Efficient transduction of healthy and malignant plasma cells by lentiviral vectors pseudotyped with measles virus glycoproteins.
Leukemia 2012;26(7):1663-70.
2012: J-M Humbert; T H N'Guyen; Els Verhoeyen; F Amirache Bouafia; S Boni; François-Loïc Cosset; Cecilia Frecha; Franck Halary
Measles virus glycoprotein-pseudotyped lentiviral vectors are highly superior to vesicular stomatitis virus G pseudotypes for genetic modification of monocyte-derived dendritic cells.
Journal of virology 2012;86(9):5192-203.
2012: Saïda Dadi; Willem A Dik; Hervé Dombret; Pierre Ferrier; Olivier Hermine; Norbert Ifrah; Anton W Langerak; Sandrine Le Noir; Ludovic Lhermitte; Elizabeth A Macintyre; Corinne Millien; Bertrand Nadel; Dominique Payet-Bornet; Arnaud Petit; Isabelle Radford; Salvatore Spicuglia; Elodie Vachez; Els Verhoeyen; Patrick Villarèse; Joaquin Zacarias-Cabeza; Julie Bergeron; François-Loïc Cosset; Vahid Asnafi
TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.
Cancer cell 2012;21(4):563-76.
2012: Francisca Molina-Jimenez; Ricardo Moreno-Otero; Jose J Marin; Rafael Aldabe; Thomas F Baumert; Ignacio Benedicto; Oscar Briz; François-Loïc Cosset; Viet Loan Dao Thi; Virginia Gondar; Dimitri Lavillette; Manuel Lopez-Cabrera; Pedro Majano
Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle.
Virology 2012;425(1):31-9.
2012: Cecilia Frecha; Didier Nègre; Paula Rio; Didier Trono; Fouzia Amirache; Juan Bueren; François-Loïc Cosset; Caroline Costa; Els Verhoeyen
A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.
Blood 2012;119(5):1139-50.
2011: Marie Dewannieux; Birke Bartosch; François-Loïc Cosset; David Ribet; Cécile Vernochet; Thierry Heidmann
The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins.
PLoS pathogens 2011;7(10):e1002309.
2011: Nishi R Sharma; François-Loïc Cosset; Marlene Dreux; Arash Grakoui; Guaniri Mateu; Gregory B Melikyan
Hepatitis C virus is primed by CD81 protein for low pH-dependent fusion.
The Journal of biological chemistry 2011;286(35):30361-76.
2011: Cyrille Mathieu; Christine Pohl; Hervé Raoul; Judit Szecsi; Selena Trajkovic-Bodennec; T Fabian Wild; François-Loïc Cosset; Séverine Devergnas; Denis Gerlier; Branka Horvat
Nipah virus uses leukocytes for efficient dissemination within a host.
Journal of virology 2011;85(15):7863-71.
2011: Guillemette Maurin; Czeslaw Wychowski; François-Loïc Cosset; Judith Fresquet; Ophélia Granio; Dimitri Lavillette
Identification of interactions in the E1E2 heterodimer of hepatitis C virus important for cell entry.
The Journal of biological chemistry 2011;286(27):23865-76.
2011: Urs F Greber; François-Loïc Cosset
Too smart to fail-how viruses exploit the complexity of host cells during entry.
Current opinion in virology 2011;1(1):3-5.
2011: Bertrand Boson; Ralf Bartenschlager; Ophélia Granio; François-Loïc Cosset
A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly.
PLoS pathogens 2011;7(7):e1002144.
2011: Cecilia Frecha; Camille Lévy; Caroline Costa; Didier Nègre; Fouzia Amirache; Robin Buckland; Steven J Russell; François-Loïc Cosset; Els Verhoeyen
Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.
Journal of virology 2011;85(12):5975-85.
2011: Joachim Lupberger; Mirjam B Zeisel; Fei Xiao; Christine Thumann; Isabel Fofana; Laetitia Zona; Christopher Davis; Christopher J Mee; Marine Turek; Sebastian Gorke; Cathy Royer; Benoit Fischer; Muhammad N Zahid; Dimitri Lavillette; Judith Fresquet; François-Loïc Cosset; S Michael Rothenberg; Thomas Pietschmann; Arvind H Patel; Patrick Pessaux; Michel Doffoël; Wolfgang Raffelsberger; Olivier Poch; Jane A McKeating; Laurent Brino; Thomas F Baumert
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy.
Nature medicine 2011;17(5):589-95.
2011: Els Verhoeyen; François-Loïc Cosset; Didier Nègre
Production of SIV vectors for gene delivery.
Cold Spring Harbor protocols 2011;2011(4):pdb.prot5598.
2011: Cecilia Frecha; Floriane Fusil; François-Loïc Cosset; Els Verhoeyen
In vivo gene delivery into hCD34+ cells in a humanized mouse model.
Methods in molecular biology (Clifton, N.J.) 2011;737():367-90.
2011: Viet Loan Dao Thi; Marlène Dreux; François-Loïc Cosset
Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation.
Expert reviews in molecular medicine 2011;13():e13.
2011: Elodie Teissier; Giorgia Zandomeneghi; Antoine Loquet; Dimitri Lavillette; Jean-Pierre Lavergne; Roland Montserret; François-Loïc Cosset; Anja Böckmann; Beat H Meier; François Penin; Eve-Isabelle Pécheur
Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol.
PloS one 2011;6(1):e15874.
2010: Cecilia Frecha; Camille Lévy; François-Loïc Cosset; Els Verhoeyen
Advances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(10):1748-57.
2010: Philippe Podevin; Arnaud Carpentier; Véronique Pène; Lynda Aoudjehane; Matthieu Carrière; Sakina Zaïdi; Céline Hernandez; Vanessa Calle; Jean-François Méritet; Olivier Scatton; Marlène Dreux; François-Loïc Cosset; Takaji Wakita; Ralf Bartenschlager; Sylvie demignot; Filoména Conti; Arielle R Rosenberg; Yvon Calmus
Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes.
Gastroenterology 2010;139(4):1355-64.
2010: Samira Fafi-Kremer; Isabel Fofana; Eric Soulier; Patric Carolla; Philip Meuleman; Geert Leroux-Roels; Arvind H Patel; François-Loïc Cosset; Patrick Pessaux; Michel Doffoël; Philippe Wolf; Françoise Stoll-Keller; Thomas F Baumert
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation.
The Journal of experimental medicine 2010;207(9):2019-31.
2010: Camille Lévy; Cecilia Frecha; Caroline Costa; Nicolas Rachinel; Gilles SALLES; François-Loïc Cosset; Els Verhoeyen
Lentiviral vectors and transduction of human cancer B cells.
Blood 2010;116(3):498-500; author reply 500.
2010: Sophie E Krieger; Mirjam B Zeisel; Christopher Davis; Christine Thumann; Helen J Harris; Eva K Schnober; Christopher Mee; Eric Soulier; Cathy Royer; Mélanie Lambotin; Fritz Grunert; Viet Loan Dao Thi; Marlène Dreux; François-Loïc Cosset; Jane A McKeating; Catherine Schuster; Thomas F Baumert
Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-claudin-1 associations.
Hepatology (Baltimore, Md.) 2010;51(4):1144-57.
2009: Cecilia Frecha; Caroline Costa; Camille Lévy; Didier Nègre; Stephen J Russell; Andrea Maisner; Gilles SALLES; Kah-Whye Peng; François-Loïc Cosset; Els Verhoeyen
Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.
Blood 2009;114(15):3173-80.
2009: Els Verhoeyen; François-Loïc Cosset
Engineering the surface glycoproteins of lentiviral vectors for targeted gene transfer.
Cold Spring Harbor protocols 2009;2009(8):pdb.top59.
2009: Els Verhoeyen; François-Loïc Cosset
Hematopoietic stem cell targeting with surface-engineered lentiviral vectors.
Cold Spring Harbor protocols 2009;2009(8):pdb.prot5276.
2009: Ignacio Benedicto; Francisca Molina-Jiménez; Birke Bartosch; François-Loïc Cosset; Dimitri Lavillette; Jesús Prieto; Ricardo Moreno-Otero; Agustín Valenzuela-Fernández; Rafael Aldabe; Manuel López-Cabrera; Pedro Majano
The tight junction-associated protein occludin is required for a postbinding step in hepatitis C virus entry and infection.
Journal of virology 2009;83(16):8012-20.
2009: Judit Szécsi; Gülsah Gabriel; Gabriella Edfeldt; Maud Michelet; Hans Dieter Klenk; François-Loïc Cosset
DNA vaccination with a single-plasmid construct coding for viruslike particles protects mice against infection with a highly pathogenic avian influenza A virus.
The Journal of infectious diseases 2009;200(2):181-90.
2009: Sofia Lourenço; Sébastien Boni; Denis Furling; François-Loïc Cosset; Annie Cahour
A cell-based bicistronic lentiviral reporter system for identification of inhibitors of the hepatitis C virus internal ribosome entry site.
Journal of virological methods 2009;158(1-2):152-9.
2009: Delphine Desjardins; Christophe Huret; Charlotte Dalba; Florian Kreppel; Stefan Kochanek; François-Loïc Cosset; Frédéric Tangy; David Klatzmann; Bertrand Bellier
Recombinant retrovirus-like particle forming DNA vaccines in prime-boost immunization and their use for hepatitis C virus vaccine development.
The journal of gene medicine 2009;11(4):313-25.
2009: François-Loïc Cosset; Philippe Marianneau; Geraldine Verney; Fabrice Gallais; Noel Tordo; Eve-Isabelle Pécheur; Jan ter Meulen; Vincent Deubel; Birke Bartosch
Characterization of Lassa virus cell entry and neutralization with Lassa virus pseudoparticles.
Journal of virology 2009;83(7):3228-37.
2009: Brigitte Chhin; Didier Negre; Olivier Merrot; Jacqueline Pham; Yves Tourneur; Denis Ressnikoff; Martine Jaspers; Mark Jorissen; François-Loïc Cosset; Patrice Bouvagnet
Ciliary beating recovery in deficient human airway epithelial cells after lentivirus ex vivo gene therapy.
PLoS genetics 2009;5(3):e1000422.
2009: Marlène Dreux; Viet Loan Dao Thi; Judith Fresquet; Maryse Guérin; Zélie Julia; Géraldine Verney; David Durantel; Fabien Zoulim; Dimitri Lavillette; François-Loïc Cosset; Birke Bartosch
Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains.
PLoS pathogens 2009;5(2):e1000310.
2009: Marlène Dreux; François-Loïc Cosset
Detection of neutralizing antibodies with HCV pseudoparticles (HCVpp).
Methods in molecular biology (Clifton, N.J.) 2009;510():427-38.
2009: Birke Bartosch; François-Loïc Cosset
Studying HCV cell entry with HCV pseudoparticles (HCVpp).
Methods in molecular biology (Clifton, N.J.) 2009;510():279-93.
2008: Cecilia Frecha; Caroline Costa; Didier Nègre; Emmanuel Gauthier; stephen russell; François-Loïc Cosset; Els Verhoeyen
Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.
Blood 2008;112(13):4843-52.
2008: Anita Haberstroh; Eva K Schnober; Mirjam B Zeisel; Patric Carolla; Heidi Barth; Hubert E Blum; François-Loïc Cosset; George Koutsoudakis; Ralf Bartenschlager; Ann union; Erik Depla; Ania Owsianka; Arvind H Patel; Catherine Schuster; Françoise Stoll-Keller; Michel Doffoël; Marlène Dreux; Thomas F Baumert
Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.
Gastroenterology 2008;135(5):1719-1728.e1.
2008: Emmanuel Fenouillet; Dimitri Lavillette; Silvia Loureiro; George Krashias; Guillemette Maurin; François-Loïc Cosset; Ian M Jones; Rym Barbouche
Contribution of redox status to hepatitis C virus E2 envelope protein function and antigenicity.
The Journal of biological chemistry 2008;283(39):26340-8.
2008: Mirjam B Zeisel; François-Loïc Cosset; Thomas F Baumert
Host neutralizing responses and pathogenesis of hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2008;48(1):299-307.
2008: Zhen-Yong Keck; Oakley Olson; Meital Gal-Tanamy; Jinming Xia; Arvind H Patel; Marlène Dreux; François-Loïc Cosset; Stanley M Lemon; Steven K H Foung
A point mutation leading to hepatitis C virus escape from neutralization by a monoclonal antibody to a conserved conformational epitope.
Journal of virology 2008;82(12):6067-72.
2008: Laurent Meertens; Claire Bertaux; Lisa Cukierman; Emmanuel G Cormier; Dimitri Lavillette; François-Loïc Cosset; Tanya Dragic
The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus.
Journal of virology 2008;82(7):3555-60.
2008: Sonia Derdouch; Wilfried Gay; Didier Nègre; Stéphane Prost; Mikael Le Dantec; Benoît Delache; Gwenaelle Auregan; THIBAULT ANDRIEU; Jean-Jacques Leplat; François-Loïc Cosset; Roger Le Grand
Reconstitution of the myeloid and lymphoid compartments after the transplantation of autologous and genetically modified CD34+ bone marrow cells, following gamma irradiation in cynomolgus macaques.
Retrovirology 2008;5():50.
2007: Mirjam B Zeisel; George Koutsoudakis; Eva K Schnober; Anita Haberstroh; Hubert E Blum; François-Loïc Cosset; Takaji Wakita; Daniel Jaeck; Michel Doffoel; Cathy Royer; Eric Soulier; Evelyne Schvoerer; Catherine Schuster; Françoise Stoll-Keller; Ralf Bartenschlager; Thomas Pietschmann; Heidi Barth; Thomas F Baumert
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.
Hepatology (Baltimore, Md.) 2007;46(6):1722-31.
2007: Marlène Dreux; Bertrand Boson; Sylvie Ricard-Blum; Jennifer Molle; Dimitri Lavillette; Birke Bartosch; Eve-Isabelle Pécheur; François-Loïc Cosset
The exchangeable apolipoprotein ApoC-I promotes membrane fusion of hepatitis C virus.
The Journal of biological chemistry 2007;282(44):32357-69.
2007: Dimitri Lavillette; Eve-Isabelle Pécheur; Peggy Donot; Judith Fresquet; Jennifer Molle; Romuald Corbau; Marlène Dreux; François Penin; François-Loïc Cosset
Characterization of fusion determinants points to the involvement of three discrete regions of both E1 and E2 glycoproteins in the membrane fusion process of hepatitis C virus.
Journal of virology 2007;81(16):8752-65.
2007: Zoya Gluzman; Belly Koren; Meir Preis; Tzafra Cohen; Adili Tsaba; François-Loïc Cosset; Rona Shofti; Basil S. Lewis; Renu Virmani; Moshe Y Flugelman
Endothelial cells are activated by angiopoeitin-1 gene transfer and produce coordinated sprouting in vitro and arteriogenesis in vivo.
Biochemical and biophysical research communications 2007;359(2):263-8.
2007: David Bouard; Virginie Sandrin; Bertrand Boson; Didier Nègre; Gary Thomas; Christelle Granier; François-Loïc Cosset
An acidic cluster of the cytoplasmic tail of the RD114 virus glycoprotein controls assembly of retroviral envelopes.
Traffic (Copenhagen, Denmark) 2007;8(7):835-47.
2007: Eve-Isabelle Pécheur; Dimitri Lavillette; Fanny Alcaras; Jennifer Molle; Yury S Boriskin; Michael Roberts; François-Loïc Cosset; Stephen Polyak
Biochemical mechanism of hepatitis C virus inhibition by the broad-spectrum antiviral arbidol.
Biochemistry 2007;46(20):6050-9.
2007: Jan M Pestka; Mirjam B Zeisel; Edith Bläser; Peter Schürmann; Birke Bartosch; François-Loïc Cosset; Arvind H Patel; Helga Meisel; Jens Baumert; Sergei Viazov; Kay Rispeter; Hubert E Blum; Michael Roggendorf; Thomas F Baumert
Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):6025-30.
2007: Cynthia Chapel; Céline Garcia; Birke Bartosch; Philippe Roingeard; Nicole Zitzmann; François-Loïc Cosset; Jean Dubuisson; Raymond A Dwek; Christian Trépo; Fabien Zoulim; David Durantel
Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors.
The Journal of general virology 2007;88(Pt 4):1133-43.
2007: Benoit de Chassey; Ivan Mikaelian; Anne-Laure Mathieu; Marc Bickle; Delphine Olivier; Didier Nègre; François-Loïc Cosset; Brian B Rudkin; Pierre Colas
An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity.
Molecular & cellular proteomics : MCP 2007;6(3):451-9.
2006: Heidi Barth; Eva K Schnober; Fuming Zhang; Robert J Linhardt; Erik Depla; Bertrand Boson; François-Loïc Cosset; Arvind H Patel; Hubert E Blum; Thomas F Baumert
Viral and cellular determinants of the hepatitis C virus envelope-heparan sulfate interaction.
Journal of virology 2006;80(21):10579-90.
2006: Judit Szécsi; Rosybel Drury; Véronique Josserand; Marie-Pierre Grange; Bertrand Boson; Irene Hartl; Richard Schneider; Christian J Buchholz; Jean-Luc Coll; stephen russell; François-Loïc Cosset; Els Verhoeyen
Targeted retroviral vectors displaying a cleavage site-engineered hemagglutinin (HA) through HA-protease interactions.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(5):735-44.
2006: Tae-Hwe Heo; Song-Mi Lee; Birke Bartosch; François-Loïc Cosset; Chang-Yuil Kang
Hepatitis C virus E2 links soluble human CD81 and SR-B1 protein.
Virus research 2006;121(1):58-64.
2006: Cécile Voisset; Anne Op De Beeck; Pauline Horellou; Marlène Dreux; Thierry Gustot; Gilles Duverlie; François-Loïc Cosset; Ngoc Vu-Dac; Jean Dubuisson
High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry.
The Journal of general virology 2006;87(Pt 9):2577-81.
2006: Marlène Dreux; Thomas Pietschmann; Christelle Granier; Cécile Voisset; Sylvie Ricard-Blum; Philippe-Emmanuel Mangeot; Zhen-Yong Keck; Steven K H Foung; Ngoc Vu-Dac; Jean Dubuisson; Ralf Bartenschlager; Dimitri Lavillette; François-Loïc Cosset
High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI.
The Journal of biological chemistry 2006;281(27):18285-95.
2006: Belly Koren; Anat Weisz; Lukas Fischer; Zoya Gluzman; Meir Preis; Naomi A Avramovitch; Tzafra Cohen; François-Loïc Cosset; Basil S. Lewis; Moshe Y Flugelman
Efficient transduction and seeding of human endothelial cells onto metallic stents using bicistronic pseudo-typed retroviral vectors encoding vascular endothelial growth factor.
Cardiovascular revascularization medicine : including molecular interventions 2006;7(3):173-8.
2006: Louise Swainson; Els Verhoeyen; François-Loïc Cosset; Naomi Taylor
IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6702-8.
2006: Thomas Pietschmann; Artur Kaul; George Koutsoudakis; Anna Shavinskaya; Stephanie Kallis; Eike Steinmann; Karim Abid; Francesco Negro; Marlene Dreux; François-Loïc Cosset; Ralf Bartenschlager
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(19):7408-13.
2006: Marlène Dreux; François-Loïc Cosset
HCV and lipoproteins: is oxLDL an Achilles' heel of the Trojan horse?
Hepatology (Baltimore, Md.) 2006;43(5):903-5.
2006: Birke Bartosch; François-Loïc Cosset
Cell entry of hepatitis C virus.
Virology 2006;348(1):1-12.
2006: Dimitri Lavillette; Rym Barbouche; Yongxiu Yao; Bertrand Boson; François-Loïc Cosset; Ian M Jones; Emmanuel Fenouillet
Significant redox insensitivity of the functions of the SARS-CoV spike glycoprotein: comparison with HIV envelope.
The Journal of biological chemistry 2006;281(14):9200-4.
2006: Bertrand Bellier; Charlotte Dalba; Béatrice Clerc; Delphine Desjardins; Rosybel Drury; François-Loïc Cosset; Mary Collins; David Klatzmann
DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant.
Vaccine 2006;24(14):2643-55.
2006: Anne-Catherine Fluckiger; Guillaume Marcy; Mélanie Marchand; Didier Négre; François-Loïc Cosset; Shoukhrat Mitalipov; Don Wolf; Pierre Savatier; Colette Dehay
Cell cycle features of primate embryonic stem cells.
Stem cells (Dayton, Ohio) 2006;24(3):547-56.
2006: Dimitri Lavillette; Birke Bartosch; Delphine Nourrisson; Géraldine Verney; François-Loïc Cosset; François Penin; Eve-Isabelle Pécheur
Hepatitis C virus glycoproteins mediate low pH-dependent membrane fusion with liposomes.
The Journal of biological chemistry 2006;281(7):3909-17.
2006: Rene Broer; Bertrand Boson; Willy Spaan; François-Loïc Cosset; Jeroen Corver
Important role for the transmembrane domain of severe acute respiratory syndrome coronavirus spike protein during entry.
Journal of virology 2006;80(3):1302-10.
2006: Virginie Sandrin; François-Loïc Cosset
Intracellular versus cell surface assembly of retroviral pseudotypes is determined by the cellular localization of the viral glycoprotein, its capacity to interact with Gag, and the expression of the Nef protein.
The Journal of biological chemistry 2006;281(1):528-42.
2006: Judit Szécsi; Bertrand Boson; Per Johnsson; Pia Dupeyrot-Lacas; Mikhail Matrosovich; Hans-Dieter Klenk; David Klatzmann; Viktor Volchkov; François-Loïc Cosset
Induction of neutralising antibodies by virus-like particles harbouring surface proteins from highly pathogenic H5N1 and H7N1 influenza viruses.
Virology journal 2006;3():70.
2005: Jin-Won Youn; Su-Hyung Park; Dimitri Lavillette; François-Loïc Cosset; Se-Hwan Yang; Chang Geun Lee; Hyun-Tak Jin; Chang-Min Kim; Mohamed Tarek Shata; Dong-Hun Lee; Wolfram Pfahler; Alfred M Prince; Young Chul Sung
Sustained E2 antibody response correlates with reduced peak viremia after hepatitis C virus infection in the chimpanzee.
Hepatology (Baltimore, Md.) 2005;42(6):1429-36.
2005: Nathalie Callens; Yann Ciczora; Birke Bartosch; Ngoc Vu-Dac; François-Loïc Cosset; Jean-Michel Pawlotsky; François Penin; Jean Dubuisson
Basic residues in hypervariable region 1 of hepatitis C virus envelope glycoprotein e2 contribute to virus entry.
Journal of virology 2005;79(24):15331-41.
2005: Virginie Sandrin; Pierre Boulanger; François Penin; Christelle Granier; François-Loïc Cosset; Birke Bartosch
Assembly of functional hepatitis C virus glycoproteins on infectious pseudoparticles occurs intracellularly and requires concomitant incorporation of E1 and E2 glycoproteins.
The Journal of general virology 2005;86(Pt 12):3189-99.
2005: Els Verhoeyen; Maciej Wiznerowicz; Delphine Olivier; Brigitte Izac; Didier Trono; Anne Dubart Kupperschmitt; François-Loïc Cosset
Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells.
Blood 2005;106(10):3386-95.
2005: Darren Schofield; Birke Bartosch; Yohko K Shimizu; Tobias Allander; Harvey Alter; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell
Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity.
Hepatology (Baltimore, Md.) 2005;42(5):1055-62.
2005: Zhen-Yong Keck; Ta-Kai Li; Jinming Xia; Birke Bartosch; François-Loïc Cosset; Jean Dubuisson; Steven K H Foung
Analysis of a highly flexible conformational immunogenic domain a in hepatitis C virus E2.
Journal of virology 2005;79(21):13199-208.
2005: Yann Ciczora; Nathalie Callens; Claire Montpellier; Birke Bartosch; François-Loïc Cosset; Anne Op De Beeck; Jean Dubuisson
Contribution of the charged residues of hepatitis C virus glycoprotein E2 transmembrane domain to the functions of the E1E2 heterodimer.
The Journal of general virology 2005;86(Pt 10):2793-8.
2005: Ania M Owsianka; Alexander W Tarr; Vicky S Juttla; Dimitri Lavillette; Birke Bartosch; François-Loïc Cosset; Jonathan K Ball; Arvind H Patel
Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein.
Journal of virology 2005;79(17):11095-104.
2005: Franck P Dupuy; Enguerran Mouly; Mariana Mesel-Lemoine; Céline Morel; Julien Abriol; Mustapha Cherai; Claude Baillou; Didier Nègre; François-Loïc Cosset; David Klatzmann; francois Lemoine
Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters.
The journal of gene medicine 2005;7(9):1158-71.
2005: Anne Goffard; Nathalie Callens; Birke Bartosch; Czeslaw Wychowski; François-Loïc Cosset; Claire Montpellier; Jean Dubuisson
Role of N-linked glycans in the functions of hepatitis C virus envelope glycoproteins.
Journal of virology 2005;79(13):8400-9.
2005: Birke Bartosch; Géraldine Verney; Marlène Dreux; Peggy Donot; Yoann Morice; François Penin; Jean-Michel Pawlotsky; Dimitri Lavillette; François-Loïc Cosset
An interplay between hypervariable region 1 of the hepatitis C virus E2 glycoprotein, the scavenger receptor BI, and high-density lipoprotein promotes both enhancement of infection and protection against neutralizing antibodies.
Journal of virology 2005;79(13):8217-29.
2005: Dimitri Lavillette; Yoann Morice; Georgios Germanidis; Peggy Donot; Alexandre Soulier; Emanuil Pagkalos; Georgios Sakellariou; Liliane Intrator; Birke Bartosch; Jean-Michel Pawlotsky; François-Loïc Cosset
Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection.
Journal of virology 2005;79(10):6023-34.
2005: Valérie Cheynet; Alessia Ruggieri; Guy Oriol; Jean-Luc Blond; Bertrand Boson; L Vachot; Bernard Verrier; François-Loïc Cosset; francois mallet
Synthesis, assembly, and processing of the Env ERVWE1/syncytin human endogenous retroviral envelope.
Journal of virology 2005;79(9):5585-93.
2005: Jean-Christophe Meunier; ronald engle; Kristina Faulk; Ming Zhao; Birke Bartosch; Harvey Alter; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell; Jens Bukh
Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4560-5.
2005: Stéphane Trajcevski; Sounkary K Solly; Charlotte Frisén; Aurelie Bauquet; François-Loïc Cosset; David Klatzmann
Characterization of a semi-replicative gene delivery system allowing propagation of complementary defective retroviral vectors.
The journal of gene medicine 2005;7(3):276-87.
2005: Dimitri Lavillette; Alexander W Tarr; Cécile Voisset; Peggy Donot; Birke Bartosch; Christine Bain; Arvind H Patel; Jean Dubuisson; Jonathan K Ball; François-Loïc Cosset
Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus.
Hepatology (Baltimore, Md.) 2005;41(2):265-74.
2004: Birke Bartosch; François-Loïc Cosset
Strategies for retargeted gene delivery using vectors derived from lentiviruses.
Current gene therapy 2004;4(4):427-43.
2004: Dragan Jevremovic; Ashwani Bhardwaj; Ivo Hennig; Rosa Maria Diaz; Caroline Cole; Laurel S Kleppe; François-Loïc Cosset; Robert D Simari; Richard G Vile
Use of blood outgrowth endothelial cells as virus-producing vectors for gene delivery to tumors.
American journal of physiology. Heart and circulatory physiology 2004;287(2):H494-500.
2004: Pierre-Yves Lozach; Ali Amara; Birke Bartosch; Jean-Louis Virelizier; Fernando Arenzana-Seisdedos; François-Loïc Cosset; Ralf Altmeyer
C-type lectins L-SIGN and DC-SIGN capture and transmit infectious hepatitis C virus pseudotype particles.
The Journal of biological chemistry 2004;279(31):32035-45.
2004: Virginie Sandrin; Delphine Muriaux; Jean-Luc Darlix; François-Loïc Cosset
Intracellular trafficking of Gag and Env proteins and their interactions modulate pseudotyping of retroviruses.
Journal of virology 2004;78(13):7153-64.
2004: Mei-ying W Yu; Birke Bartosch; Pei Zhang; Zheng-ping Guo; Paula M Renzi; Li-Ming Shen; Christelle Granier; Stephen M Feinstone; François-Loïc Cosset; Robert Purcell
Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(20):7705-10.
2004: B L Strang; Y Ikeda; François-Loïc Cosset; Mary K Collins; Yasuhiro Takeuchi
Characterization of HIV-1 vectors with gammaretrovirus envelope glycoproteins produced from stable packaging cells.
Gene therapy 2004;11(7):591-8.
2004: Anne Op De Beeck; Cécile Voisset; Birke Bartosch; Yann Ciczora; Laurence Cocquerel; Zhen-Yong Keck; Steven K H Foung; François-Loïc Cosset; Jean Dubuisson
Characterization of functional hepatitis C virus envelope glycoproteins.
Journal of virology 2004;78(6):2994-3002.
2004: Els Verhoeyen; François-Loïc Cosset
Surface-engineering of lentiviral vectors.
The journal of gene medicine 2004;6 Suppl 1():S83-94.
2004: Philippe-Emmanuel Mangeot; François-Loïc Cosset; Pierre Colas; Ivan Mikaelian
A universal transgene silencing method based on RNA interference.
Nucleic acids research 2004;32(12):e102.
2004: Stelios Psarras; Niki Karagianni; Christoph Kellendonk; François Tronche; François-Loïc Cosset; Carol Stocking; Volker Schirrmacher; Harald von Boehmer Hv; Khashayarsha Khazaie
Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors.
The journal of gene medicine 2004;6(1):32-42.
2004: Sandra Blaise; Alessia Ruggieri; Marie Dewannieux; François-Loïc Cosset; Thierry Heidmann
Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians.
Journal of virology 2004;78(2):1050-4.
2003: Birke Bartosch; Jens Bukh; Jean-Christophe Meunier; Christelle Granier; ronald engle; William C Blackwelder; Suzanne U Emerson; François-Loïc Cosset; Robert Purcell
In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14199-204.
2003: Birke Bartosch; alessandra vitelli; Christelle Granier; Caroline Goujon; Jean Dubuisson; Simona Pascale; Elisa Scarselli; Riccardo Cortese; Alfredo Nicosia; François-Loïc Cosset
Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor.
The Journal of biological chemistry 2003;278(43):41624-30.
2003: Marka Crittenden; Michael Gough; John Chester; Timothy Kottke; Jill Thompson; Anja Ruchatz; Tim Clackson; François-Loïc Cosset; Heung Chong; Rosa Maria Diaz; Kevin Harrington; Luis Alvarez-Vallina; Richard Vile
Pharmacologically regulated production of targeted retrovirus from T cells for systemic antitumor gene therapy.
Cancer research 2003;63(12):3173-80.
2003: Yasuhiro Ikeda; Yasuhiro Takeuchi; Francisco Martin; François-Loïc Cosset; Kyriacos A Mitrophanous; Mary Collins
Continuous high-titer HIV-1 vector production.
Nature biotechnology 2003;21(5):569-72.
2003: Els Verhoeyen; Valerie Dardalhon; Odile Ducrey-Rundquist; Didier Trono; Naomi Taylor; François-Loïc Cosset
IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes.
Blood 2003;101(6):2167-74.
2003: Birke Bartosch; Jean Dubuisson; François-Loïc Cosset
Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes.
The Journal of experimental medicine 2003;197(5):633-42.
2003: Francisco Martin; Simon Chowdhury; Stuart J D Neil; Kerry A Chester; François-Loïc Cosset; Mary K Collins
Targeted retroviral infection of tumor cells by receptor cooperation.
Journal of virology 2003;77(4):2753-6.
2003: Virginie Sandrin; stephen russell; François-Loïc Cosset
Targeting retroviral and lentiviral vectors.
Current topics in microbiology and immunology 2003;281():137-78.
2003: Alessia Ruggieri; Didier Nègre; François-Loïc Cosset
SIV Vectors.
Methods in molecular biology (Clifton, N.J.) 2003;229():233-49.
2002: Didier Nègre; François-Loïc Cosset
Vectors derived from simian immunodeficiency virus (SIV).
Biochimie 2002;84(11):1161-71.
2002: Ghislaine Duisit; Hervé Conrath; Sylvie Saleun; Sébastien Folliot; Nathalie Provost; François-Loïc Cosset; Virginie Sandrin; Philippe Moullier; Fabienne Rolling
Five recombinant simian immunodeficiency virus pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):446-54.
2002: Dimitri Lavillette; Alessia Ruggieri; Bertrand Boson; Marielle Maurice; François-Loïc Cosset
Relationship between SU subdomains that regulate the receptor-mediated transition from the native (fusion-inhibited) to the fusion-active conformation of the murine leukemia virus glycoprotein.
Journal of virology 2002;76(19):9673-85.
2002: Virginie Sandrin; Bertrand Boson; Patrick Salmon; Wilfried Gay; Didier Nègre; Roger Le Grand; Didier Trono; François-Loïc Cosset
Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates.
Blood 2002;100(3):823-32.
2002: Michael Leslie Roberts; Dominic J Wells; Ian R Graham; Stewart A Fabb; Vanessa J Hill; Ghislaine Duisit; Katsutoshi Yuasa; Shin'ichi Takeda; François-Loïc Cosset; George Dickson
Stable micro-dystrophin gene transfer using an integrating adeno-retroviral hybrid vector ameliorates the dystrophic pathology in mdx mouse muscle.
Human molecular genetics 2002;11(15):1719-30.
2002: Dimitri Lavillette; Mariana Marin; Alessia Ruggieri; francois mallet; François-Loïc Cosset; David Kabat
The envelope glycoprotein of human endogenous retrovirus type W uses a divergent family of amino acid transporters/cell surface receptors.
Journal of virology 2002;76(13):6442-52.
2002: Marielle Maurice; Els Verhoeyen; Patrick Salmon; Didier Trono; stephen russell; François-Loïc Cosset
Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide.
Blood 2002;99(7):2342-50.
2002: John Chester; Anja Ruchatz; Michael Gough; Marka Crittenden; Heung Chong; François-Loïc Cosset; François Loïc-Cosset; Rosa Maria Diaz; Kevin Harrington; Luis Alvarez-Vallina; Richard Vile
Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells.
Nature biotechnology 2002;20(3):256-63.
2002: Philippe-Emmanuel Mangeot; Karine Duperrier; Didier Nègre; Bertrand Boson; Dominique Rigal; François-Loïc Cosset; Jean-Luc Darlix
High levels of transduction of human dendritic cells with optimized SIV vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(3):283-90.
2002: Didier Nègre; Ghislaine Duisit; Philippe-Emmanuel Mangeot; Philippe Moullier; Jean-Luc Darlix; François-Loïc Cosset
Lentiviral vectors derived from simian immunodeficiency virus.
Current topics in microbiology and immunology 2002;261():53-74.
2001: Michael Leslie Roberts; Takis Athanasopoulos; M Pohlschmidt; Ghislaine Duisit; François-Loïc Cosset; George Dickson
Post-mitotic, differentiated myotubes efficiently produce retroviral vector from hybrid adeno-retrovirus templates.
Gene therapy 2001;8(20):1580-6.
2001: Dimitri Lavillette; stephen russell; François-Loïc Cosset
Retargeting gene delivery using surface-engineered retroviral vector particles.
Current opinion in biotechnology 2001;12(5):461-6.
2001: Dimitri Lavillette; Bertrand Boson; stephen russell; François-Loïc Cosset
Activation of membrane fusion by murine leukemia viruses is controlled in cis or in trans by interactions between the receptor-binding domain and a conserved disulfide loop of the carboxy terminus of the surface glycoprotein.
Journal of virology 2001;75(8):3685-95.
2000: JC Zhao-Emonet; Gilles Marodon; C Pioche-Durieu; François-Loïc Cosset; David Klatzmann
T cell-specific expression from Mo-MLV retroviral vectors containing a CD4 mini-promoter/enhancer.
The journal of gene medicine 2000;2(6):416-25.
2000: Didier Nègre; Philippe-Emmanuel Mangeot; Ghislaine Duisit; S Blanchard; Pierre-Olivier Vidalain; Philippe Leissner; A J Winter; Chantal Rabourdin-Combe; Majid Mehtali; Philippe Moullier; Jean-Luc Darlix; François-Loïc Cosset
Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells.
Gene therapy 2000;7(19):1613-23.
2000: Philippe-Emmanuel Mangeot; Didier Nègre; B Dubois; A J Winter; Philippe Leissner; Majid Mehtali; D Kaiserlian; François-Loïc Cosset; Jean-Luc Darlix
Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells.
Journal of virology 2000;74(18):8307-15.
2000: Felix J Kim; I Seiliez; C Denesvre; Dimitri Lavillette; François-Loïc Cosset; Marc Sitbon
Definition of an amino-terminal domain of the human T-cell leukemia virus type 1 envelope surface unit that extends the fusogenic range of an ecotropic murine leukemia virus.
The Journal of biological chemistry 2000;275(31):23417-20.
2000: A K Fielding; S Chapel-Fernandes; M P Chadwick; FJ Bullough; François-Loïc Cosset; stephen russell
A hyperfusogenic gibbon ape leukemia envelope glycoprotein: targeting of a cytotoxic gene by ligand display.
Human gene therapy 2000;11(6):817-26.
2000: Jean-Luc Blond; Dimitri Lavillette; Valérie Cheynet; Olivier Bouton; Guy Oriol; S Chapel-Fernandes; Bernard Mandrand; francois mallet; François-Loïc Cosset
An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor.
Journal of virology 2000;74(7):3321-9.
2000: Andrew Bateman; FJ Bullough; S Murphy; Lisa Emiliusen; D Lavillette; François-Loïc Cosset; Roberto Cattaneo; stephen russell; Richard G Vile
Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth.
Cancer research 2000;60(6):1492-7.
2000: T Hatziioannou; stephen russell; François-Loïc Cosset
Incorporation of simian virus 5 fusion protein into murine leukemia virus particles and its effect on the co-incorporation of retroviral envelope glycoproteins.
Virology 2000;267(1):49-57.
2000: Dimitri Lavillette; Alessia Ruggieri; stephen russell; François-Loïc Cosset
Activation of a cell entry pathway common to type C mammalian retroviruses by soluble envelope fragments.
Journal of virology 2000;74(1):295-304.
1999: stephen russell; François-Loïc Cosset
Modifying the host range properties of retroviral vectors.
The journal of gene medicine 1999;1(5):300-11.
1999: Kah-Whye Peng; Richard Vile; François-Loïc Cosset; S Russell
Selective transduction of protease-rich tumors by matrix-metalloproteinase-targeted retroviral vectors.
Gene therapy 1999;6(9):1552-7.
1999: Francisco Martin; Stuart J D Neil; J Kupsch; M Maurice; François-Loïc Cosset; Mary Collins
Retrovirus targeting by tropism restriction to melanoma cells.
Journal of virology 1999;73(8):6923-9.
1999: Marielle Maurice; S Mazur; FJ Bullough; A Salvetti; M K Collins; stephen russell; François-Loïc Cosset
Efficient gene delivery to quiescent interleukin-2 (IL-2)-dependent cells by murine leukemia virus-derived vectors harboring IL-2 chimeric envelope glycoproteins.
Blood 1999;94(2):401-10.
1999: T Hatziioannou; E Delahaye; F Martin; stephen russell; François-Loïc Cosset
Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin.
Human gene therapy 1999;10(9):1533-44.
1999: Ghislaine Duisit; Anna Salvetti; Philippe Moullier; François-Loïc Cosset
Functional characterization of adenoviral/retroviral chimeric vectors and their use for efficient screening of retroviral producer cell lines.
Human gene therapy 1999;10(2):189-200.
1999: M Movassagh; Claude Baillou; François-Loïc Cosset; David Klatzmann; Martine Guigon; francois Lemoine
High level of retrovirus-mediated gene transfer into dendritic cells derived from cord blood and mobilized peripheral blood CD34+ cells.
Human gene therapy 1999;10(2):175-87.
1999: M P Chadwick; F J Morling; François-Loïc Cosset; stephen russell
Modification of retroviral tropism by display of IGF-I.
Journal of molecular biology 1999;285(2):485-94.
1998: Dimitri Lavillette; Marielle Maurice; C Roche; stephen russell; Marc Sitbon; François-Loïc Cosset
A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopes.
Journal of virology 1998;72(12):9955-65.
1998: A Marandin; Anne Dubart; Françoise Pflumio; François-Loïc Cosset; V Cordette; S Chapel-Fernandes; Laure Coulombel; William Vainchenker; Fawzia Louache
Retrovirus-mediated gene transfer into human CD34+38low primitive cells capable of reconstituting long-term cultures in vitro and nonobese diabetic-severe combined immunodeficiency mice in vivo.
Human gene therapy 1998;9(10):1497-511.
1998: T Hatziioannou; S Valsesia-Wittmann; stephen russell; François-Loïc Cosset
Incorporation of fowl plague virus hemagglutinin into murine leukemia virus particles and analysis of the infectivity of the pseudotyped retroviruses.
Journal of virology 1998;72(6):5313-7.
1998: F Martin; J Kupsch; Y Takeuchi; S Russell; François-Loïc Cosset; M Collins
Retroviral vector targeting to melanoma cells by single-chain antibody incorporation in envelope.
Human gene therapy 1998;9(5):737-46.
1998: A K Fielding; M Maurice; F J Morling; François-Loïc Cosset; stephen russell
Inverse targeting of retroviral vectors: selective gene transfer in a mixed population of hematopoietic and nonhematopoietic cells.
Blood 1998;91(5):1802-9.
1997: N Savard; François-Loïc Cosset; Alberto L Epstein
Defective herpes simplex virus type 1 vectors harboring gag, pol, and env genes can be used to rescue defective retrovirus vectors.
Journal of virology 1997;71(5):4111-7.
1997: S Valsesia-Wittmann; F J Morling; T Hatziioannou; stephen russell; François-Loïc Cosset
Receptor co-operation in retrovirus entry: recruitment of an auxiliary entry mechanism after retargeted binding.
The EMBO journal 1997;16(6):1214-23.
1996: S Ager; B H Nilson; F J Morling; Kah-Whye Peng; François-Loïc Cosset; stephen russell
Retroviral display of antibody fragments; interdomain spacing strongly influences vector infectivity.
Human gene therapy 1996;7(17):2157-64.
1996: François-Loïc Cosset; stephen russell
Targeting retrovirus entry.
Gene therapy 1996;3(11):946-56.
1996: A Girod; A Drynda; François-Loïc Cosset; Gérard Verdier; C Ronfort
Homologous and nonhomologous retroviral recombinations are both involved in the transfer by infectious particles of defective avian leukosis virus-derived transcomplementing genomes.
Journal of virology 1996;70(8):5651-7.
1996: C Denesvre; C Carrington; A Corbin; Y Takeuchi; François-Loïc Cosset; T Schulz; M Sitbon; Pierre Sonigo
TM domain swapping of murine leukemia virus and human T-cell leukemia virus envelopes confers different infectious abilities despite similar incorporation into virions.
Journal of virology 1996;70(7):4380-6.
1996: I Jouan-Dufournel; François-Loïc Cosset; D Contamine; Gérard Verdier; Christian Biémont
Transposable elements behavior following viral genomic stress in Drosophila melanogaster inbred line.
Journal of molecular evolution 1996;43(1):19-27.
1996: B H Nilson; F J Morling; François-Loïc Cosset; stephen russell
Targeting of retroviral vectors through protease-substrate interactions.
Gene therapy 1996;3(4):280-6.
1996: S Valsesia-Wittmann; F J Morling; B H Nilson; Y Takeuchi; stephen russell; François-Loïc Cosset
Improvement of retroviral retargeting by using amino acid spacers between an additional binding domain and the N terminus of Moloney murine leukemia virus SU.
Journal of virology 1996;70(3):2059-64.
1995: P Thoraval; M Afanassieff; François-Loïc Cosset; F Lasserre; Gérard Verdier; F Coudert; G Dambrine
Germline transmission of exogenous genes in chickens using helper-free ecotropic avian leukosis virus-based vectors.
Transgenic research 1995;4(6):369-77.
1995: François-Loïc Cosset; F J Morling; Y Takeuchi; R A Weiss; M K Collins; stephen russell
Retroviral retargeting by envelopes expressing an N-terminal binding domain.
Journal of virology 1995;69(10):6314-22.
1995: A Girod; François-Loïc Cosset; Gérard Verdier; C Ronfort
Analysis of ALV-based packaging cell lines for production of contaminant defective viruses.
Virology 1995;209(2):671-5.
1995: C Ronfort; A Girod; François-Loïc Cosset; Catherine Legras; V M Nigon; Yahia Chebloune; Gérard Verdier
Defective retroviral endogenous RNA is efficiently transmitted by infectious particles produced on an avian retroviral vector packaging cell line.
Virology 1995;207(1):271-5.
1995: C Ronfort; Yahia Chebloune; François-Loïc Cosset; C Faure; V M Nigon; Gérard Verdier
Structure and expression of endogenous retroviral sequences in the permanent LMH chicken cell line.
Poultry science 1995;74(1):127-35.
1994: S Valsesia-Wittmann; A Drynda; G Deléage; M Aumailley; J M Heard; O Danos; Gérard Verdier; François-Loïc Cosset
Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors.
Journal of virology 1994;68(7):4609-19.
1993: Thierry Jaffredo; R M Molina; A E al Moustafa; Rodolphe Gautier; François-Loïc Cosset; Gérard Verdier; Françoise Dieterlen-Lièvre
Patterns of integration and expression of retroviral, non-replicative vectors in avian embryos: embryo developmental stage and virus subgroup envelope modulate tissue-tropism.
Cell adhesion and communication 1993;1(2):119-32.
1993: Claude BAGNIS; François-Loïc Cosset; Jacques Samarut; G Moscovici; C Moscovici
Leukemogenicity of v-myb-transformed monoblasts cells can be modulated by normal bone marrow environment.
Oncogene 1993;8(3):737-43.
1993: François-Loïc Cosset; A Girod; Frédéric Flamant; A Drynda; C Ronfort; S Valsesia; R M Molina; C Faure; V M Nigon; Gérard Verdier
Use of helper cells with two host ranges to generate high-titer retroviral vectors.
Virology 1993;193(1):385-95.
1993: Frédéric Flamant; D Aubert; C Legrand; François-Loïc Cosset; Jacques Samarut
Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors.
The Journal of general virology 1993;74 ( Pt 1)():39-46.
1992: François-Loïc Cosset; C Ronfort; R M Molina; Frédéric Flamant; A Drynda; M Benchaibi; S Valsesia; V M Nigon; Gérard Verdier
Packaging cells for avian leukosis virus-based vectors with various host ranges.
Journal of virology 1992;66(9):5671-6.
1992: J L Thomas; M Afanassieff; François-Loïc Cosset; R M Molina; C Ronfort; A Drynda; Catherine Legras; Yahia Chebloune; V M Nigon; Gérard Verdier
In situ expression of helper-free avian leukosis virus (ALV)-based retrovirus vectors in early chick embryos.
The International journal of developmental biology 1992;36(2):215-27.
1991: François-Loïc Cosset; J F Bouquet; A Drynda; Yahia Chebloune; A Rey-Senelonge; G Kohen; V M Nigon; P Desmettre; Gérard Verdier
Newcastle disease virus (NDV) vaccine based on immunization with avian cells expressing the NDV hemagglutinin-neuraminidase glycoprotein.
Virology 1991;185(2):862-6.
1991: Yahia Chebloune; J Rulka; François-Loïc Cosset; S Valsesia; C Ronfort; Catherine Legras; A Drynda; J Kuzmak; V M Nigon; Gérard Verdier
Immune response and resistance to Rous sarcoma virus challenge of chickens immunized with cell-associated glycoproteins provided with a recombinant avian leukosis virus.
Journal of virology 1991;65(10):5374-80.
1991: François-Loïc Cosset; Catherine Legras; J L Thomas; R M Molina; Yahia Chebloune; C Faure; V M Nigon; Gérard Verdier
Improvement of avian leukosis virus (ALV)-based retrovirus vectors by using different cis-acting sequences from ALVs.
Journal of virology 1991;65(6):3388-94.
1990: François-Loïc Cosset; Catherine Legras; Yahia Chebloune; Pierre Savatier; P Thoraval; J L Thomas; Jacques Samarut; V M Nigon; Gérard Verdier
A new avian leukosis virus-based packaging cell line that uses two separate transcomplementing helper genomes.
Journal of virology 1990;64(3):1070-8.
1989: Pierre Savatier; Claude BAGNIS; P Thoraval; D Poncet; M Belakebi; francois mallet; Catherine Legras; François-Loïc Cosset; J L Thomas; Yahia Chebloune
Generation of a helper cell line for packaging avian leukosis virus-based vectors.
Journal of virology 1989;63(2):513-22.

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François-Loïc Cosset

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