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Lucio Costa

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TOP 3
Judit Marsillach; Lucio G Costa; Clement E Furlong
Protein adducts as biomarkers of exposure to organophosphorus compounds.
Lucio G Costa; Gennaro Giordano; Judit Marsillach; Toby B Cole; Clement E Furlong
Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity.
Gennaro Giordano; Terrance J Kavanagh; L Tait; Toby B Cole; Clement E Furlong; Lucio G Costa
Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression.

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All Publications

2013: Judit Marsillach; Lucio G Costa; Clement E Furlong
Protein adducts as biomarkers of exposure to organophosphorus compounds.
Toxicology 2013;307():46-54.
2013: Lucio G Costa; Gennaro Giordano; Judit Marsillach; Toby B Cole; Clement E Furlong
Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity.
Toxicology 2013;307():115-22.
2013: Gennaro Giordano; Terrance J Kavanagh; L Tait; Toby B Cole; Clement E Furlong; Lucio G Costa
Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression.
Free radical biology & medicine 2013;58():98-108.
2013: Gennaro Giordano; Terrance J Kavanagh; Collin C White; Elaine M Faustman; Lucio G Costa
Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(2):399-408.
2013: Jing Chen; Lucio G Costa; Handojo Kusumo; Xiaolu Zhang; Marina Guizzetti
Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis.
Biochimica et biophysica acta 2013;1831(2):263-75.
2012: Claudia Pellacani; Annamaria Buschini; Susanna Franzoni; Serena Galati; Francesca Mussi; Lucio G Costa
Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells.
International journal of toxicology 2012;31(4):372-9.
2012: Gennaro Giordano; Lucio G Costa
Morphological assessment of neurite outgrowth in hippocampal neuron-astrocyte co-cultures.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2012;Chapter 11():Unit 11.16..
2012: Toby B Cole; Lucio G Costa; Jenna C Fisher; Thomas M Burbacher; Clement E Furlong
Neurobehavioral assessment of mice following repeated postnatal exposure to chlorpyrifos-oxon.
Neurotoxicology and teratology 2012;34(3):311-22.
2012: Lucio G Costa; Michael Aschner
An interview with Lucio G. Costa and Michael Aschner, section editors for toxicology.
BMC pharmacology & toxicology 2012;13():16.
2011: Gennaro Giordano; Marina Guizzetti; Hayley A Mattison; Khoi Dao; Lucio G Costa
Ethanol impairs muscarinic receptor-induced neuritogenesis in rat hippocampal slices: Role of astrocytes and extracellular matrix proteins.
Biochemical pharmacology 2011;82(11):1792-9.
2011: Gennaro Giordano; Clement E Furlong; Toby B Cole; Lucio G Costa
Paraoxonase 2 (PON2) in the mouse central nervous system: a neuroprotective role?
Toxicology and applied pharmacology 2011;256(3):369-78.
2011: Jordi Camps; Lucio G Costa; Dragomir I Draganov; Antonio Hernández; Sven Horke; Richard James; Jorge Joven; Bharti Mackness; Michael Mackness; Mohamed Navab; György Paragh; Srinivasa Reddy; Daniel Rochu; Ildikó Seres; Diana Shih; Dan Tawfik; Michael Aviram
Paraoxonase-1 and clopidogrel efficacy.
Nature medicine 2011;17(9):1041-2; author reply 1042-4.
2011: Toby B Cole; Lucio G Costa; Federico M Farin; Theo K Bammler; Richard P Beyer; Sarah S Park; Clement E Furlong
Repeated developmental exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects on cerebellar gene expression.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(1):155-69.
2011: Jing Chen; Lucio G Costa; Marina Guizzetti
Retinoic acid isomers up-regulate ATP binding cassette A1 and G1 and cholesterol efflux in rat astrocytes: implications for their therapeutic and teratogenic effects.
The Journal of pharmacology and experimental therapeutics 2011;338(3):870-8.
2011: Marina Guizzetti; Nadia H Moore; Kathryn L VanDeMark; Gennaro Giordano; Lucio G Costa
Muscarinic receptor-activated signal transduction pathways involved in the neuritogenic effect of astrocytes in hippocampal neurons.
European journal of pharmacology 2011;659(2-3):102-7.
2011: Elena Verzelloni; Claudia Pellacani; Davide Tagliazucchi; Sara Tagliaferri; Luca Calani; Lucio G Costa; Furio Brighenti; Gina Borges; Alan Crozier; Angela Conte; Daniele Del Rio
Antiglycative and neuroprotective activity of colon-derived polyphenol catabolites.
Molecular nutrition & food research 2011;55 Suppl 1():S35-43.
2011: Lucio G Costa; Gennaro Giordano; Clement E Furlong
Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on.
Biochemical pharmacology 2011;81(3):337-44.
2011: Jing Chen; Lucio G Costa; Marina Guizzetti
Assessment of cholesterol homeostasis in astrocytes and neurons.
Methods in molecular biology (Clifton, N.J.) 2011;758():403-14.
2011: Pamela J Roqué; Gennaro Giordano; Marina Guizzetti; Lucio G Costa
Quantification of synaptic structure formation in cocultures of astrocytes and hippocampal neurons.
Methods in molecular biology (Clifton, N.J.) 2011;758():361-90.
2011: Marina Guizzetti; Terrance J Kavanagh; Lucio G Costa
Measurements of astrocyte proliferation.
Methods in molecular biology (Clifton, N.J.) 2011;758():349-59.
2011: Gennaro Giordano; Collin C White; Lucio G Costa
Assessment of glutathione homeostasis.
Methods in molecular biology (Clifton, N.J.) 2011;758():205-14.
2011: Gennaro Giordano; Lucio G Costa
Measurements of neuronal apoptosis.
Methods in molecular biology (Clifton, N.J.) 2011;758():179-93.
2011: Gennaro Giordano; Sungwoo Hong; Elaine M Faustman; Lucio G Costa
Measurements of cell death in neuronal and glial cells.
Methods in molecular biology (Clifton, N.J.) 2011;758():171-8.
2011: Gennaro Giordano; Lucio G Costa
Primary neurons in culture and neuronal cell lines for in vitro neurotoxicological studies.
Methods in molecular biology (Clifton, N.J.) 2011;758():13-27.
2011: Lucio G Costa; Gennaro Giordano; Marina Guizzetti
In vitro neurotoxicology: an introduction.
Methods in molecular biology (Clifton, N.J.) 2011;758():1-9.
2011: Toby B Cole; Gennaro Giordano; Aila L Co; Isaac Mohar; Terrance J Kavanagh; Lucio G Costa
Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress.
Journal of toxicology 2011;2011():157687.
2011: Lucio G Costa; Gennaro Giordano
Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant?
Neurotoxicology 2011;32(1):9-24.
2010: Clement E Furlong; S M Suzuki; R C Stevens; J Marsillach; Rebecca J Richter; Gail P Jarvik; Harvey Checkoway; Ali Samii; Lucio G Costa; Alida Griffith; John W Roberts; Dora Yearout; Cyrus Zabetian
Human PON1, a biomarker of risk of disease and exposure.
Chemico-biological interactions 2010;187(1-3):355-61.
2010: Marina Guizzetti; Nadia H Moore; Gennaro Giordano; Kathryn L VanDeMark; Lucio G Costa
Ethanol inhibits neuritogenesis induced by astrocyte muscarinic receptors.
Glia 2010;58(12):1395-406.
2010: Lucio G Costa; Gennaro Giordano; Elaine M Faustman
Domoic acid as a developmental neurotoxin.
Neurotoxicology 2010;31(5):409-23.
2010: Annabella Vitalone; Assia Catalani; Carlo Cinque; Vittorio Fattori; Patrizia Matteucci; Anna Rita Zuena; Lucio G Costa
Long-term effects of developmental exposure to low doses of PCB 126 and methylmercury.
Toxicology letters 2010;197(1):38-45.
2010: Suping C Huang; Gennaro Giordano; Lucio G Costa
Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons.
Toxicological sciences : an official journal of the Society of Toxicology 2010;114(1):124-32.
2010: Sara Tagliaferri; Andrea Caglieri; Matteo Goldoni; Silvana Pinelli; Rossella Alinovi; Diana Poli; Claudia Pellacani; Gennaro Giordano; Antonio Mutti; Lucio G Costa
Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(1):116-22.
2010: Toby B Cole; Karen Jansen; Sarah Park; Wan-Fen Li; Clement E Furlong; Lucio G Costa
The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status.
Advances in experimental medicine and biology 2010;660():47-60.
2009: Kathryn L VanDemark; Marina Guizzetti; Gennaro Giordano; Lucio G Costa
Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons.
Alcoholism, clinical and experimental research 2009;33(11):1945-55.
2009: Gennaro Giordano; Daniella Pizzurro; Kathryn VanDeMark; Marina Guizzetti; Lucio G Costa
Manganese inhibits the ability of astrocytes to promote neuronal differentiation.
Toxicology and applied pharmacology 2009;240(2):226-35.
2009: Kathryn L VanDeMark; Marina Guizzetti; Gennaro Giordano; Lucio G Costa
The activation of M1 muscarinic receptor signaling induces neuronal differentiation in pyramidal hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 2009;329(2):532-42.
2009: Karen L Jansen; Toby B Cole; Sarah S Park; Clement E Furlong; Lucio G Costa
Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds.
Toxicology and applied pharmacology 2009;236(2):142-53.
2009: Gennaro Giordano; Li Li; Collin C White; Federico M Farin; Hui W Wilkerson; Terrance J Kavanagh; Lucio G Costa
Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells.
Journal of neurochemistry 2009;109(2):525-38.
2009: Gennaro Giordano; Terrance J Kavanagh; Lucio G Costa
Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71.
Neurotoxicology 2009;30(2):326-9.
2009: Nadia H Moore; Lucio G Costa; Scott A Shaffer; David R Goodlett; Marina Guizzetti
Shotgun proteomics implicates extracellular matrix proteins and protease systems in neuronal development induced by astrocyte cholinergic stimulation.
Journal of neurochemistry 2009;108(4):891-908.
2008: Lucio G Costa; Gennaro Giordano; Sara Tagliaferri; Andrea Caglieri; Antonio Mutti
Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects.
Acta bio-medica : Atenei Parmensis 2008;79(3):172-83.
2008: Marina Guizzetti; Nadia H Moore; Gennaro Giordano; Lucio G Costa
Modulation of neuritogenesis by astrocyte muscarinic receptors.
The Journal of biological chemistry 2008;283(46):31884-97.
2008: Gennaro Giordano; Terrance J Kavanagh; Lucio G Costa
Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels.
Toxicology and applied pharmacology 2008;232(2):161-8.
2008: Marina Guizzetti; Lucio G Costa
Sonic hedgehog in Smith-Lemli-Opitz syndrome and tumor development.
Journal of pediatric hematology/oncology 2008;30(9):641-2.
2008: Anna K Bal-Price; Cristina Suñol; Dieter Weiss; Erwin van Vliet; Remco H S Westerink; Lucio G Costa
Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.
Neurotoxicology 2008;29(3):520-31.
2008: Ryozo Tsuji; Vittorio Fattori; Shin-ichi Abe; Lucio G Costa; Kumiko Kobayashi
Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain.
Neurotoxicology and teratology 2008;30(3):228-36.
2008: Gennaro Giordano; H M Klintworth; Terrance J Kavanagh; Lucio G Costa
Apoptosis induced by domoic acid in mouse cerebellar granule neurons involves activation of p38 and JNK MAP kinases.
Neurochemistry international 2008;52(6):1100-5.
2008: Vittorio Fattori; Shin-ichi Abe; Kumiko Kobayashi; Lucio G Costa; Ryozo Tsuji
Effects of postnatal ethanol exposure on neurotrophic factors and signal transduction pathways in rat brain.
Journal of applied toxicology : JAT 2008;28(3):370-6.
2008: Annabella Vitalone; Anna Rita Zuena; Assia Catalani; Valentina Chiodi; Carlo Cinque; Vittorio Fattori; Matteo Goldoni; Patrizia Matteucci; Diana Poli; Lucio G Costa
Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development.
Environmental toxicology and pharmacology 2008;25(1):103-13.
2008: David Eaton; Robert B Daroff; Herman Autrup; James Bridges; Patricia Buffler; Lucio G Costa; Joseph Coyle; Guy M McKhann; William C. Mobley; Lynn Nadel; Diether Neubert; Rolf Schulte-Hermann; Peter S Spencer
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment.
Critical reviews in toxicology 2008;38 Suppl 2():1-125.
2008: Lucio G Costa; Gennaro Giordano; Marina Guizzetti; Annabella Vitalone
Neurotoxicity of pesticides: a brief review.
Frontiers in bioscience : a journal and virtual library 2008;13():1240-9.
2007: Gennaro Giordano; Collin C White; Isaac Mohar; Terrance J Kavanagh; Lucio G Costa
Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells.
Toxicological sciences : an official journal of the Society of Toxicology 2007;100(2):433-44.
2007: Lucio G Costa; Gennaro Giordano
Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants.
Neurotoxicology 2007;28(6):1047-67.
2007: Lucio G Costa
Contaminants in fish: risk-benefit considerations.
Arhiv za higijenu rada i toksikologiju 2007;58(3):367-74.
2007: Lucio G Costa; Vittorio Fattori; Gennaro Giordano; Annabella Vitalone
An in vitro approach to assess the toxicity of certain food contaminants: methylmercury and polychlorinated biphenyls.
Toxicology 2007;237(1-3):65-76.
2007: Marina Guizzetti; Jing Chen; John F Oram; Ryozo Tsuji; Khoi Dao; Thomas Möller; Lucio G Costa
Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes.
The Journal of biological chemistry 2007;282(26):18740-9.
2007: Marina Guizzetti; Lucio G Costa
Cholesterol homeostasis in the developing brain: a possible new target for ethanol.
Human & experimental toxicology 2007;26(4):355-60.
2007: Gennaro Giordano; Zahra Afsharinejad; Marina Guizzetti; Annabella Vitalone; Terrance J Kavanagh; Lucio G Costa
Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency.
Toxicology and applied pharmacology 2007;219(2-3):181-9.
2006: Gennaro Giordano; Collin C White; Lisa A McConnachie; Carolina Fernandez; Terrance J Kavanagh; Lucio G Costa
Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency.
Molecular pharmacology 2006;70(6):2116-26.
2006: Samir N Kelada; Harvey Checkoway; Sharon L R Kardia; Christopher S Carlson; Paola Costa-Mallen; David Eaton; Jordan Firestone; Karen M Powers; Phillip D Swanson; Gary M Franklin; William T Longstreth; Terri-Smith Weller; Zahra Afsharinejad; Lucio G Costa
5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study.
Human molecular genetics 2006;15(20):3055-62.
2006: Lucio G Costa
Current issues in organophosphate toxicology.
Clinica chimica acta; international journal of clinical chemistry 2006;366(1-2):1-13.
2005: Marina Guizzetti; Shantha Pathak; Gennaro Giordano; Lucio G Costa
Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation.
Toxicology 2005;215(3):182-90.
2005: Paola Costa-Mallen; Lucio G Costa; Harvey Checkoway
Genotype combinations for monoamine oxidase-B intron 13 polymorphism and dopamine D2 receptor TaqIB polymorphism are associated with ever-smoking status among men.
Neuroscience letters 2005;385(2):158-62.
2005: Samir N Kelada; Paola Costa-Mallen; Harvey Checkoway; Christopher S Carlson; Terri-Smith Weller; Phillip D Swanson; Gary M Franklin; William T Longstreth; Zahra Afsharinejad; Lucio G Costa
Dopamine transporter (SLC6A3) 5' region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's disease.
Pharmacogenetics and genomics 2005;15(9):659-68.
2005: Clement E Furlong; Toby B Cole; Gail P Jarvik; Christina Pettan-Brewer; Gary K Geiss; Rebecca J Richter; Diana M Shih; Aaron D Tward; Aldons J Lusis; Lucio G Costa
Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants.
Neurotoxicology 2005;26(4):651-9.
2005: Toby B Cole; Betsy J Walter; Diana M Shih; Aaron D Tward; Aldons J Lusis; Charles Timchalk; Rebecca J Richter; Lucio G Costa; Clement E Furlong
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism.
Pharmacogenetics and genomics 2005;15(8):589-98.
2005: Gennaro Giordano; Ana M Sánchez-Pérez; Carmina Montoliu; Ronald Berezney; Kishore Malyavantham; Lucio G Costa; Juan J Calvete; Vicente Felipo
Activation of NMDA receptors induces protein kinase A-mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA-induced neuronal death.
Journal of neurochemistry 2005;94(3):808-18.
2005: Paola Costa-Mallen; Samir N Kelada; Lucio G Costa; Harvey Checkoway
Characterization of the in vitro transcriptional activity of polymorphic alleles of the human monoamine oxidase-B gene.
Neuroscience letters 2005;383(1-2):171-5.
2005: Lucio G Costa; Marina Guizzetti; Annabella Vitalone
Diet-brain connections: role of neurotoxicants.
Environmental toxicology and pharmacology 2005;19(3):395-400.
2005: Igor Branchi; Francesca Capone; Annabella Vitalone; Federica Madia; Daniela Santucci; Enrico Alleva; Lucio G Costa
Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route.
Neurotoxicology 2005;26(2):183-92.
2005: Lucio G Costa; Annabella Vitalone; Toby B Cole; Clement E Furlong
Modulation of paraoxonase (PON1) activity.
Biochemical pharmacology 2005;69(4):541-50.
2005: Lucio G Costa; Toby B Cole; Annabella Vitalone; Clement E Furlong
Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity.
Clinica chimica acta; international journal of clinical chemistry 2005;352(1-2):37-47.
2005: Lucio G Costa; Toby B Cole; Clement E Furlong
Paraoxonase (PON1): from toxicology to cardiovascular medicine.
Acta bio-medica : Atenei Parmensis 2005;76 Suppl 2():50-7.
2005: Clement E Furlong; Toby B Cole; Betsy J Walter; Diana M Shih; Aaron D Tward; Aldons J Lusis; Charles Timchalk; Rebecca J Richter; Lucio G Costa
Paraoxonase 1 (PON1) status and risk of insecticide exposure.
Journal of biochemical and molecular toxicology 2005;19(3):182-3.
2005: Marina Guizzetti; Lucio G Costa
Disruption of cholesterol homeostasis in the developing brain as a potential mechanism contributing to the developmental neurotoxicity of ethanol: an hypothesis.
Medical hypotheses 2005;64(3):563-7.
2005: Gennaro Giordano; Ana M Sanchez-Perez; Maria Burgal; Carmina Montoliu; Lucio G Costa; Vicente Felipo
Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture.
Journal of neurochemistry 2005;92(1):143-57.
2004: Federica Madia; Gennaro Giordano; Vittorio Fattori; Annabella Vitalone; Igor Branchi; Francesca Capone; Lucio G Costa
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.
Toxicology letters 2004;154(1-2):11-21.
2004: Marina Guizzetti; Brian D Thompson; Yunie Kim; Kathryn VanDeMark; Lucio G Costa
Role of phospholipase D signaling in ethanol-induced inhibition of carbachol-stimulated DNA synthesis of 1321N1 astrocytoma cells.
Journal of neurochemistry 2004;90(3):646-53.
2004: Rebecca J Richter; Rachel L Jampsa; Gail P Jarvik; Lucio G Costa; Clement E Furlong
Determination of paraoxonase 1 status and genotypes at specific polymorphic sites.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2004;Chapter 4():Unit4.12.
2004: Lucio G Costa; Annabella Vitalone; Marina Guizzetti
Signal transduction mechanisms involved in the antiproliferative effects of ethanol in glial cells.
Toxicology letters 2004;149(1-3):67-73.
2004: Lucio G Costa; Luca Steardo; Vincenzo Cuomo
Structural effects and neurofunctional sequelae of developmental exposure to psychotherapeutic drugs: experimental and clinical aspects.
Pharmacological reviews 2004;56(1):103-47.
2004: Lucio G Costa; Michael Aschner; Annabella Vitalone; Tore Syversen; Offie P Soldin
Developmental neuropathology of environmental agents.
Annual review of pharmacology and toxicology 2004;44():87-110.
2004: Paola Costa-Mallen; Zahra Afsharinejad; Samir N Kelada; Lucio G Costa; Gary M Franklin; Phillip D Swanson; William T Longstreth; Hannah-Malia A Viernes; Federico M Farin; Terri Smith-Weller; Harvey Checkoway
DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls.
Movement disorders : official journal of the Movement Disorder Society 2004;19(1):76-83.
2003: Annabella Vitalone; Janice McColl; Dean Thome; Lucio G Costa; Beatrice Tita
Characterization of the effect of Epilobium extracts on human cell proliferation.
Pharmacology 2003;69(2):79-87.
2003: Lucio G Costa
Correspondence re: Navas-Acien et al., Interactive effect of chemical substances and occupational electromagnetic field exposure on the risk of gliomas and meningiomas in Swedish men. 11:1678-1683, 2002.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(9):950.
2003: Maria Grazia Evandri; Lucio G Costa; Paola Bolle
Evaluation of brominated diphenyl ether-99 toxicity with Raphidocelis subcapitata and Daphnia magna.
Environmental toxicology and chemistry / SETAC 2003;22(9):2167-72.
2003: Ryozo Tsuji; Marina Guizzetti; Lucio G Costa
In vivo ethanol decreases phosphorylated MAPK and p70S6 kinase in the developing rat brain.
Neuroreport 2003;14(10):1395-9.
2003: Lucio G Costa; Piero Lovreglio; Annabella Vitalone; Leonardo Soleo
[Role of genetic polymorphism in risk assessment].
Giornale italiano di medicina del lavoro ed ergonomia 2003;25(3):320-7.
2003: Marina Guizzetti; Thomas Möller; Lucio G Costa
Ethanol inhibits muscarinic receptor-mediated DNA synthesis and signal transduction in human fetal astrocytes.
Neuroscience letters 2003;344(1):68-70.
2003: Igor Branchi; Francesca Capone; Enrico Alleva; Lucio G Costa
Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure.
Neurotoxicology 2003;24(3):449-62.
2003: Toby B Cole; Rachel Jampsa; Betsy J Walter; Tara L Arndt; Rebecca J Richter; Diana M Shih; Aaron D Tward; Aldons J Lusis; Rhona M Jack; Lucio G Costa; Clement E Furlong
Expression of human paraoxonase (PON1) during development.
Pharmacogenetics 2003;13(6):357-64.
2003: Annabella Vitalone; Marina Guizzetti; Lucio G Costa; Beatrice Tita
Extracts of various species of Epilobium inhibit proliferation of human prostate cells.
The Journal of pharmacy and pharmacology 2003;55(5):683-90.
2003: Samir N Kelada; Paola Costa-Mallen; Harvey Checkoway; H A Viernes; Federico M Farin; Terri Smith-Weller; Gary M Franklin; Lucio G Costa; William T Longstreth; Clement E Furlong; Gail P Jarvik; Phillip D Swanson
Paraoxonase 1 promoter and coding region polymorphisms in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 2003;74(4):546-7.
2003: Maria Grazia Evandri; Sabina Mastrangelo; Lucio G Costa; Paola Bolle
In vitro assessment of mutagenicity and clastogenicity of BDE-99, a pentabrominated diphenyl ether flame retardant.
Environmental and molecular mutagenesis 2003;42(2):85-90.
2003: Marina Guizzetti; F Bordi; Francisco J Dieguez-Acuña; Annabella Vitalone; Federica Madia; James S Woods; Lucio G Costa
Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol.
Neuroscience 2003;120(4):941-50.
2003: Mark Burry; Marina Guizzetti; Jan Oberdoerster; Lucio G Costa
Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells.
Developmental neuroscience 2003;25(1):14-9.
2003: Lucio G Costa; Toby B Cole; Clement E Furlong
Polymorphisms of paraoxonase (PON1) and their significance in clinical toxicology of organophosphates.
Journal of toxicology. Clinical toxicology 2003;41(1):37-45.
2003: Lucio G Costa; Toby B Cole; Gail P Jarvik; Clement E Furlong
Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism.
Annual review of medicine 2003;54():371-92.
2003: Lucio G Costa; Rebecca J Richter; Wan-Fen Li; Toby Cole; Marina Guizzetti; Clement E Furlong
Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2003;8(1):1-12.
2002: Lucio G Costa; Marina Guizzetti
Inhibition of muscarinic receptor-induced proliferation of astroglial cells by ethanol: mechanisms and implications for the fetal alcohol syndrome.
Neurotoxicology 2002;23(6):685-91.
2002: Samir N Kelada; Paola Costa-Mallen; Lucio G Costa; Terri Smith-Weller; Gary M Franklin; Phillip D Swanson; William T Longstreth; Harvey Checkoway
Gender difference in the interaction of smoking and monoamine oxidase B intron 13 genotype in Parkinson's disease.
Neurotoxicology 2002;23(4-5):515-9.
2002: Igor Branchi; Enrico Alleva; Lucio G Costa
Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development.
Neurotoxicology 2002;23(3):375-84.
2002: Marina Guizzetti; Lucio G Costa
Effect of ethanol on protein kinase Czeta and p70S6 kinase activation by carbachol: a possible mechanism for ethanol-induced inhibition of glial cell proliferation.
Journal of neurochemistry 2002;82(1):38-46.
2002: Clement E Furlong; Toby B Cole; Gail P Jarvik; Lucio G Costa
Pharmacogenomic considerations of the paraoxonase polymorphisms.
Pharmacogenomics 2002;3(3):341-8.
2002: Hailing Lu; Marina Guizzetti; Lucio G Costa
Inorganic lead activates the mitogen-activated protein kinase kinase-mitogen-activated protein kinase-p90(RSK) signaling pathway in human astrocytoma cells via a protein kinase C-dependent mechanism.
The Journal of pharmacology and experimental therapeutics 2002;300(3):818-23.
2002: Lucio G Costa; Marina Guizzetti; M Burry; Jan Oberdoerster
Developmental neurotoxicity: do similar phenotypes indicate a common mode of action? A comparison of fetal alcohol syndrome, toluene embryopathy and maternal phenylketonuria.
Toxicology letters 2002;127(1-3):197-205.
2001: Hailing Lu; Marina Guizzetti; Lucio G Costa
Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Calpha.
Journal of neurochemistry 2001;78(3):590-9.
2001: K Yagle; Hailing Lu; Marina Guizzetti; T Möller; Lucio G Costa
Activation of mitogen-activated protein kinase by muscarinic receptors in astroglial cells: role in DNA synthesis and effect of ethanol.
Glia 2001;35(2):111-20.
2001: Marina Guizzetti; Lucio G Costa
Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells.
Neuroreport 2001;12(8):1639-42.
2001: Lucio G Costa; Marina Guizzetti; Hailing Lu; F Bordi; Annabella Vitalone; Beatrice Tita; Maura Palmery; Pacifico Valeri; B Silvestrini
Intracellular signal transduction pathways as targets for neurotoxicants.
Toxicology 2001;160(1-3):19-26.
2001: MC Catlin; Lucio G Costa; M Guizzetti; R A Ponce; Terrance J Kavanagh
Analytical cytology: applications to neurotoxicology.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2001;Chapter 12():Unit12.5.
2001: Lucio G Costa; Marina Guizzetti; Jan Oberdoerster; K Yagle; Paola Costa-Mallen; Beatrice Tita; F Bordi; Annabella Vitalone; Maura Palmery; Pacifico Valeri
Modulation of DNA synthesis by muscarinic cholinergic receptors.
Growth factors (Chur, Switzerland) 2001;18(4):227-36.
2000: Marina Guizzetti; Lucio G Costa
Muscarinic receptors, protein kinase C isozymes and proliferation of astroglial cells: effects of ethanol.
Neurotoxicology 2000;21(6):1117-21.
2000: Wan-Fen Li; Lucio G Costa; Rebecca J Richter; T Hagen; Diana M Shih; Aaron D Tward; Aldons J Lusis; Clement E Furlong
Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds.
Pharmacogenetics 2000;10(9):767-79.
2000: Marina Guizzetti; Lucio G Costa
Possible role of protein kinase C zeta in muscarinic receptor-induced proliferation of astrocytoma cells.
Biochemical pharmacology 2000;60(10):1457-66.
2000: David Eaton; Lucio G Costa
Sheldon D. Murphy.
Toxicological sciences : an official journal of the Society of Toxicology 2000;57(2):191-2.
2000: MC Catlin; T J Kavanagh; Lucio G Costa
Muscarinic receptor-induced calcium responses in astroglia.
Cytometry 2000;41(2):123-32.
2000: Jan Oberdoerster; Marina Guizzetti; Lucio G Costa
Effect of phenylalanine and its metabolites on the proliferation and viability of neuronal and astroglial cells: possible relevance in maternal phenylketonuria.
The Journal of pharmacology and experimental therapeutics 2000;295(1):295-301.
2000: Paola Costa-Mallen; Lucio G Costa; Terri Smith-Weller; Gary M Franklin; Phillip D Swanson; Harvey Checkoway
Genetic polymorphism of dopamine D2 receptors in Parkinson's disease and interactions with cigarette smoking and MAO-B intron 13 polymorphism.
Journal of neurology, neurosurgery, and psychiatry 2000;69(4):535-7.
2000: Clement E Furlong; Wan-Fen Li; Victoria H Brophy; Gail P Jarvik; Rebecca J Richter; Diana M Shih; Aldons J Lusis; Lucio G Costa
The PON1 gene and detoxication.
Neurotoxicology 2000;21(4):581-7.
2000: MC Catlin; Marina Guizzetti; Lucio G Costa
Effect of ethanol on muscarinic receptor-induced calcium responses in astroglia.
Journal of neuroscience research 2000;60(3):345-55.
2000: Clement E Furlong; Wan-Fen Li; Rebecca J Richter; Diana M Shih; Aldons J Lusis; E Alleva; Lucio G Costa
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1).
Neurotoxicology 2000;21(1-2):91-100.
2000: Lucio G Costa
The emerging field of ecogenetics.
Neurotoxicology 2000;21(1-2):85-9.
2000: M Wei; Marina Guizzetti; Michael G Yost; Lucio G Costa
Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro.
Toxicology and applied pharmacology 2000;162(3):166-76.
2000: Paola Costa-Mallen; Harvey Checkoway; Mark A Fishel; A W Cohen; Terri Smith-Weller; Gary M Franklin; Phillip D Swanson; Lucio G Costa
The EcoRV genetic polymorphism of human monoamine oxidase type A is not associated with Parkinson's disease and does not modify the effect of smoking on Parkinson's disease.
Neuroscience letters 2000;278(1-2):33-6.
1999: Lucio G Costa; Wan-Fen Li; Rebecca J Richter; Diana M Shih; Aldons J Lusis; Clement E Furlong
The role of paraoxonase (PON1) in the detoxication of organophosphates and its human polymorphism.
Chemico-biological interactions 1999;119-120():429-38.
1999: Lucio G Costa; Marina Guizzetti
Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanol.
Biochemical pharmacology 1999;57(7):721-6.
1999: K Yagle; Lucio G Costa
Effects of alcohol on immediate-early gene expression in primary cultures of rat cortical astrocytes.
Alcoholism, clinical and experimental research 1999;23(3):446-55.
1999: MC Catlin; Marina Guizzetti; Lucio G Costa
Effects of ethanol on calcium homeostasis in the nervous system: implications for astrocytes.
Molecular neurobiology 1999;19(1):1-24.
1998: Lucio G Costa
Biochemical and molecular neurotoxicology: relevance to biomarker development, neurotoxicity testing and risk assessment.
Toxicology letters 1998;102-103():417-21.
1998: Marina Guizzetti; M Wei; Lucio G Costa
The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line.
European journal of pharmacology 1998;359(2-3):223-33.
1998: Clement E Furlong; Wan-Fen Li; Lucio G Costa; Rebecca J Richter; Diana M Shih; Aldons J Lusis
Genetically determined susceptibility to organophosphorus insecticides and nerve agents: developing a mouse model for the human PON1 polymorphism.
Neurotoxicology 1998;19(4-5):645-50.
1998: Harvey Checkoway; Federico M Farin; Paola Costa-Mallen; SC Kirchner; Lucio G Costa
Genetic polymorphisms in Parkinson's disease.
Neurotoxicology 1998;19(4-5):635-43.
1998: Diana M Shih; L Gu; Yu-Rong Xia; Mohamad Navab; Wan-Fen Li; Susan Hama; Lawrence W Castellani; Clement E Furlong; Lucio G Costa; Alan M Fogelman; Aldons J Lusis
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis.
Nature 1998;394(6690):284-7.
1998: Harvey Checkoway; Gary M Franklin; Paola Costa-Mallen; Terri Smith-Weller; J Dilley; Phillip D Swanson; Lucio G Costa
A genetic polymorphism of MAO-B modifies the association of cigarette smoking and Parkinson's disease.
Neurology 1998;50(5):1458-61.
1998: Lucio G Costa
Neurotoxicity testing: a discussion of in vitro alternatives.
Environmental health perspectives 1998;106 Suppl 2():505-10.
1998: B H Alexander; Harvey Checkoway; Paola Costa-Mallen; Elaine M Faustman; James S Woods; K T Kelsey; C van Netten; Lucio G Costa
Interaction of blood lead and delta-aminolevulinic acid dehydratase genotype on markers of heme synthesis and sperm production in lead smelter workers.
Environmental health perspectives 1998;106(4):213-6.
1998: Lucio G Costa
Signal transduction in environmental neurotoxicity.
Annual review of pharmacology and toxicology 1998;38():21-43.
1997: Marina Guizzetti; MC Catlin; Lucio G Costa
The effects of ethanol on glial cell proliferation: relevance to the fetal alcohol syndrome.
Frontiers in bioscience : a journal and virtual library 1997;2():e93-8.
1997: P Costa; Harvey Checkoway; D Levy; Terri Smith-Weller; Gary M Franklin; Phillip D Swanson; Lucio G Costa
Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease.
American journal of medical genetics 1997;74(2):154-6.
1997: Lucio G Costa
Basic toxicology of pesticides.
Occupational medicine (Philadelphia, Pa.) 1997;12(2):251-68.
1997: Wan-Fen Li; C Matthews; Christine M Disteche; Lucio G Costa; Clement E Furlong
Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression.
Pharmacogenetics 1997;7(2):137-44.
1996: Marina Guizzetti; Lucio G Costa
Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol.
Journal of neurochemistry 1996;67(6):2236-45.
1996: Anna F Castoldi; Stefano M Candura; P Costa; Luigi Manzo; Lucio G Costa
Interaction of mercury compounds with muscarinic receptor subtypes in the rat brain.
Neurotoxicology 1996;17(3-4):735-41.
1996: Lucio G Costa
Biomarker research in neurotoxicology: the role of mechanistic studies to bridge the gap between the laboratory and epidemiological investigations.
Environmental health perspectives 1996;104 Suppl 1():55-67.
1996: Marina Guizzetti; P Costa; J Peters; Lucio G Costa
Acetylcholine as a mitogen: muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells.
European journal of pharmacology 1996;297(3):265-73.
1996: Teresa Coccini; Amalia Di Nucci; Marcello Tonini; Luciano Maestri; Lucio G Costa; M Liuzzi; Luigi Manzo
Effects of ethanol administration on cerebral non-protein sulfhydryl content in rats exposed to styrene vapour.
Toxicology 1996;106(1-3):115-22.
1996: Teresa Coccini; Luciano Maestri; F S Robustelli della Cuna; L Bin; Lucio G Costa; Luigi Manzo
Urinary mercapturic acid diastereoisomers in rats subchronically exposed to styrene and ethanol.
Archives of toxicology 1996;70(11):736-41.
1996: K Yagle; Lucio G Costa
Effects of organophosphate exposure on muscarinic acetylcholine receptor subtype mRNA levels in the adult rat.
Neurotoxicology 1996;17(2):523-30.
1995: K A Kovacs; Terrance J Kavanagh; Lucio G Costa
Ethanol inhibits muscarinic receptor-stimulated phosphoinositide metabolism and calcium mobilization in rat primary cortical cultures.
Neurochemical research 1995;20(8):939-49.
1995: P Costa; C B Auger; D J Traver; Lucio G Costa
Identification of m3, m4 and m5 subtypes of muscarinic receptor mRNA in human blood mononuclear cells.
Journal of neuroimmunology 1995;60(1-2):45-51.
1995: X X Tan; Lucio G Costa
Postnatal development of muscarinic receptor-stimulated phosphoinositide metabolism in mouse cerebral cortex: sensitivity to ethanol.
Brain research. Developmental brain research 1995;86(1-2):348-53.
1995: Dan Segerbäck; C J Calleman; J L Schroeder; Lucio G Costa; Elaine M Faustman
Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide.
Carcinogenesis 1995;16(5):1161-5.
1995: Luigi Manzo; Anna F Castoldi; Teresa Coccini; A D Rossi; P Nicotera; Lucio G Costa
Mechanisms of neurotoxicity: applications to human biomonitoring.
Toxicology letters 1995;77(1-3):63-72.
1995: Lucio G Costa; Luigi Manzo
Biochemical markers of neurotoxicity: research strategies and epidemiological applications.
Toxicology letters 1995;77(1-3):137-44.
1995: Lucio G Costa; H Deng; C J Calleman; E Bergmark
Evaluation of the neurotoxicity of glycidamide, an epoxide metabolite of acrylamide: behavioral, neurochemical and morphological studies.
Toxicology 1995;98(1-3):151-61.
1995: Wan-Fen Li; Clement E Furlong; Lucio G Costa
Paraoxonase protects against chlorpyrifos toxicity in mice.
Toxicology letters 1995;76(3):219-26.
1995: X X Tan; Lucio G Costa
Long-lasting microencephaly following exposure to cocaine during the brain growth spurt in the rat.
Brain research. Developmental brain research 1995;84(2):179-84.
1995: Walter Balduini; F Renò; Lucio G Costa
Interaction of ethanol and anoxia with muscarinic receptor--stimulated phosphoinositide metabolism during brain development.
Life sciences 1995;57(18):1667-73.
1994: C F Gregotti; Z Kirby; Luigi Manzo; Lucio G Costa; Elaine M Faustman
Effects of styrene oxide on differentiation and viability of rodent embryo cultures.
Toxicology and applied pharmacology 1994;128(1):25-35.
1994: P Costa; D J Traver; C B Auger; Lucio G Costa
Expression of cholinergic muscarinic receptor subtypes mRNA in rat blood mononuclear cells.
Immunopharmacology 1994;28(2):113-23.
1994: X X Tan; Lucio G Costa
Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain.
Brain research. Developmental brain research 1994;79(1):132-5.
1994: Anna F Castoldi; Teresa Coccini; A Rossi; P Nicotera; Lucio G Costa; X X Tan; Luigi Manzo
Biomarkers in environmental medicine: alterations of cell signalling as early indicators of neurotoxicity.
Functional neurology 1994;9(2):101-9.
1994: P Costa; Anna F Castoldi; D J Traver; Lucio G Costa
Lack of m2 muscarinic acetylcholine receptor mRNA in rat lymphocytes.
Journal of neuroimmunology 1994;49(1-2):115-24.
1994: Lucio G Costa
Signal transduction mechanisms in developmental neurotoxicity: the phosphoinositide pathway.
Neurotoxicology 1994;15(1):19-27.
1994: Harvey Checkoway; Diana Echeverria; J D Moon; Nicholas J Heyer; Lucio G Costa
Platelet monoamine oxidase B activity in workers exposed to styrene.
International archives of occupational and environmental health 1994;66(5):359-62.
1994: Luigi Manzo; C Locatelli; Stefano M Candura; Lucio G Costa
Nutrition and alcohol neurotoxicity.
Neurotoxicology 1994;15(3):555-65.
1993: Wan-Fen Li; Lucio G Costa; Clement E Furlong
Serum paraoxonase status: a major factor in determining resistance to organophosphates.
Journal of toxicology and environmental health 1993;40(2-3):337-46.
1993: X X Tan; Anna F Castoldi; Luigi Manzo; Lucio G Costa
Interaction of ethanol with muscarinic receptor-stimulated phosphoinositide metabolism during the brain growth spurt in the rat: role of acetaldehyde.
Neuroscience letters 1993;156(1-2):13-6.
1993: Clement E Furlong; Lucio G Costa; Christopher Hassett; Rebecca J Richter; J A Sundstrom; D A Adler; Christine M Disteche; Curtis J Omiecinski; C Chapline; John W Crabb
Human and rabbit paraoxonases: purification, cloning, sequencing, mapping and role of polymorphism in organophosphate detoxification.
Chemico-biological interactions 1993;87(1-3):35-48.
1993: Teresa Coccini; Stefano M Candura; Luigi Manzo; Lucio G Costa; Marcello Tonini
Interaction of the neurotoxic pesticides ivermectin and lindane with the enteric GABAA receptor-ionophore complex in the guinea-pig.
European journal of pharmacology 1993;248(1):1-6.
1993: E Bergmark; C J Calleman; F He; Lucio G Costa
Determination of hemoglobin adducts in humans occupationally exposed to acrylamide.
Toxicology and applied pharmacology 1993;120(1):45-54.
1993: Anna F Castoldi; Luigi Manzo; Lucio G Costa
Cyclic GMP formation induced by muscarinic receptors is mediated by nitric oxide synthesis in rat cortical primary cultures.
Brain research 1993;610(1):57-61.
1993: C Tang; Anna F Castoldi; Lucio G Costa
Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes.
Biochemistry and molecular biology international 1993;29(6):1047-54.
1993: C J Calleman; E Bergmark; L G Stern; Lucio G Costa
A nonlinear dosimetric model for hemoglobin adduct formation by the neurotoxic agent acrylamide and its genotoxic metabolite glycidamide.
Environmental health perspectives 1993;99():221-3.
1993: B B Fitzgerald; Lucio G Costa
Modulation of muscarinic receptors and acetylcholinesterase activity in lymphocytes and in brain areas following repeated organophosphate exposure in rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;20(2):210-6.
1993: X X Tan; C Tang; Anna F Castoldi; Luigi Manzo; Lucio G Costa
Effects of inorganic and organic mercury on intracellular calcium levels in rat T lymphocytes.
Journal of toxicology and environmental health 1993;38(2):159-70.
1993: H Deng; F He; S Zhang; C J Calleman; Lucio G Costa
Quantitative measurements of vibration threshold in healthy adults and acrylamide workers.
International archives of occupational and environmental health 1993;65(1):53-6.
1993: Anna F Castoldi; Lucio G Costa; Luigi Manzo
[Oncogenes as indicators of occupational exposure to carcinogenic agents].
Giornale italiano di medicina del lavoro 1993;15(1-4):45-50.
1992: Luigi Manzo; Lucio G Costa; M Tonini; Claudio Minoia; E Sabbioni
Metabolic studies as a basis for the interpretation of metal toxicity.
Toxicology letters 1992;64-65 Spec No():677-86.
1992: Stefano M Candura; P Marraccini; Lucio G Costa; Luigi Manzo; A Rossi; Teresa Coccini; Marcello Tonini
Calcium entry blockade as a mechanism for chlordimeform-induced inhibition of motor activity in the isolated guinea-pig ileum.
Pharmacology & toxicology 1992;71(6):426-33.
1992: B B Fitzgerald; Lucio G Costa
Modulation of M1 and M2 muscarinic receptor subtypes following repeated organophosphate exposure in rats.
Toxicology and applied pharmacology 1992;117(1):122-5.
1992: Stefano M Candura; Anna F Castoldi; Luigi Manzo; Lucio G Costa
Guanine nucleotide- and muscarinic agonist-dependent phosphoinositide metabolism in synaptoneurosomes from cerebral cortex of immature rats.
Neurochemical research 1992;17(11):1133-41.
1992: C Karr; P Demers; Lucio G Costa; William Daniell; Scott Barnhart; M Miller; G Gallagher; S W Horstman; D Eaton; Linda Rosenstock
Organophosphate pesticide exposure in a group of Washington State orchard applicators.
Environmental research 1992;59(1):229-37.
1992: William Daniell; Scott Barnhart; P Demers; Lucio G Costa; David Eaton; M Miller; Linda Rosenstock
Neuropsychological performance among agricultural pesticide applicators.
Environmental research 1992;59(1):217-28.
1992: Harvey Checkoway; Lucio G Costa; J Camp; Teresa Coccini; William Daniell; Russell L Dills
Peripheral markers of neurochemical function among workers exposed to styrene.
British journal of industrial medicine 1992;49(8):560-5.
1992: C J Calleman; L G Stern; E Bergmark; Lucio G Costa
Linear versus nonlinear models for hemoglobin adduct formation by acrylamide and its metabolite glycidamide: implications for risk estimation.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1992;1(5):361-8.
1992: C Gregotti; Amalia Di Nucci; Lucio G Costa; Luigi Manzo; R Scelsi; F Bertè; Elaine M Faustman
Effects of thallium on primary cultures of testicular cells.
Journal of toxicology and environmental health 1992;36(1):59-69.
1992: Lucio G Costa; H Deng; C Gregotti; Luigi Manzo; Elaine M Faustman; E Bergmark; C J Calleman
Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat.
Neurotoxicology 1992;13(1):219-24.
1992: Harvey Checkoway; Lucio G Costa; James S Woods; Anna F Castoldi; B O Lund; Phillip D Swanson
Peripheral blood cell activities of monoamine oxidase B and superoxide dismutase in Parkinson's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1992;4():283-90.
1992: Stefano M Candura; Luigi Manzo; Lucio G Costa
Inhibition of muscarinic receptor- and G-protein-dependent phosphoinositide metabolism in cerebrocortical membranes from neonatal rats by ethanol.
Neurotoxicology 1992;13(1):281-8.
1991: Anna F Castoldi; B Fitzgerald; Luigi Manzo; Marcello Tonini; Lucio G Costa
Muscarinic M2 receptors in rat brain labeled with [3H] AF-DX 384.
Research communications in chemical pathology and pharmacology 1991;74(3):371-4.
1991: E Bergmark; C J Calleman; Lucio G Costa
Formation of hemoglobin adducts of acrylamide and its epoxide metabolite glycidamide in the rat.
Toxicology and applied pharmacology 1991;111(2):352-63.
1991: Walter Balduini; Stefano M Candura; Luigi Manzo; Flaminio Nicola Cattabeni; Lucio G Costa
Time-, concentration-, and age-dependent inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by ethanol in the developing rat brain.
Neurochemical research 1991;16(11):1235-40.
1991: Walter Balduini; Stefano M Candura; Lucio G Costa
Regional development of carbachol-, glutamate-, norepinephrine-, and serotonin-stimulated phosphoinositide metabolism in rat brain.
Brain research. Developmental brain research 1991;62(1):115-20.
1991: Teresa Coccini; Luigi Manzo; Lucio G Costa
3H-spiperone labels sigma receptors, not dopamine D2 receptors, in rat and human lymphocytes.
Immunopharmacology 1991;22(2):93-105.
1991: Lucio G Costa; J Gastel; S D Murphy
The formamidine pesticides chlordimeform and amitraz decrease hepatic glutathione in mice through an interaction with alpha 2-adrenoceptors.
Journal of toxicology and environmental health 1991;33(3):349-58.
1991: Teresa Coccini; Lucio G Costa; Luigi Manzo; Stefano M Candura; N Iapadre; Barbara Balestra; Marcello Tonini
Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons.
European journal of pharmacology 1991;198(1):105-8.
1991: Stefano M Candura; Anna F Castoldi; Luigi Manzo; Lucio G Costa
Interaction of aluminum ions with phosphoinositide metabolism in rat cerebral cortical membranes.
Life sciences 1991;49(17):1245-52.
1991: Stefano M Candura; Walter Balduini; Lucio G Costa
Interaction of short chain aliphatic alcohols with muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex from neonatal and adult rats.
Neurotoxicology 1991;12(1):23-32.
1991: L S Wechsler; Harvey Checkoway; G M Franklin; Lucio G Costa
A pilot study of occupational and environmental risk factors for Parkinson's disease.
Neurotoxicology 1991;12(3):387-92.
1991: C A Trenga; D D Kunkel; David Eaton; Lucio G Costa
Effect of styrene oxide on rat brain glutathione.
Neurotoxicology 1991;12(2):165-78.
1990: Stefano M Candura; Teresa Coccini; Luigi Manzo; Lucio G Costa
Interaction of sigma-compounds with receptor-stimulated phosphoinositide metabolism in the rat brain.
Journal of neurochemistry 1990;55(5):1741-8.
1990: Walter Balduini; Lucio G Costa
Characterization of ouabain-induced phosphoinositide hydrolysis in brain slices of the neonatal rat.
Neurochemical research 1990;15(10):1023-9.
1990: C J Calleman; E Bergmark; Lucio G Costa
Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation.
Chemical research in toxicology 1990;3(5):406-12.
1990: Lucio G Costa
The phosphoinositide/protein kinase C system as a potential target for neurotoxicity.
Pharmacological research : the official journal of the Italian Pharmacological Society 1990;22(4):393-408.
1990: Walter Balduini; S D Murphy; Lucio G Costa
Characterization of cholinergic muscarinic receptor-stimulated phosphoinositide metabolism in brain from immature rats.
The Journal of pharmacology and experimental therapeutics 1990;253(2):573-9.
1990: Walter Balduini; Lucio G Costa
Developmental neurotoxicity of ethanol: in vitro inhibition of muscarinic receptor-stimulated phosphoinositide metabolism in brain from neonatal but not adult rats.
Brain research 1990;512(2):248-52.
1990: W E Maier; Lucio G Costa
Na+/K(+)-ATPase in rat brain and erythrocytes as a possible target and marker, respectively, for neurotoxicity: studies with chlordecone, organotins and mercury compounds.
Toxicology letters 1990;51(2):175-88.
1990: Lucio G Costa; B E McDonald; S D Murphy; Gilbert S Omenn; Rebecca J Richter; Arno G Motulsky; Clement E Furlong
Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats.
Toxicology and applied pharmacology 1990;103(1):66-76.
1990: D Wu; Lucio G Costa; S D Murphy
[The effect of pesticides-CDM and AMZ on inhibition of the binding of 3H-clonidine to alpha 2-adrenoreceptor in rat forebrain tissue].
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao / [bian ji zhe, Hua xi yi ke da xue xue bao bian wei hui] 1990;21(1):17-21.
1990: Lucio G Costa; G Kaylor; S D Murphy
In vitro and in vivo modulation of cholinergic muscarinic receptors in rat lymphocytes and brain by cholinergic agents.
International journal of immunopharmacology 1990;12(1):67-75.
1990: Walter Balduini; Lucio G Costa; S D Murphy
Potassium ions potentiate the muscarinic receptor-stimulated phosphoinositide metabolism in cerebral cortex slices: a comparison of neonatal and adult rats.
Neurochemical research 1990;15(1):33-9.
1989: Walter Balduini; Lucio G Costa
Effects of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development.
The Journal of pharmacology and experimental therapeutics 1989;250(2):541-7.
1989: Clement E Furlong; Rebecca J Richter; S L Seidel; Lucio G Costa; Arno G Motulsky
Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase.
Analytical biochemistry 1989;180(2):242-7.
1989: Lucio G Costa; D S Wu; G Olibet; S D Murphy
Formamidine pesticides and alpha 2-adrenoceptors: studies with amitraz and chlordimeform in rats and development of a radioreceptor binding assay.
Neurotoxicology and teratology 1989;11(4):405-11.
1989: Lucio G Costa; G Olibet; D S Wu; S D Murphy
Acute and chronic effects of the pesticide amitraz on alpha 2-adrenoceptors in mouse brain.
Toxicology letters 1989;47(2):135-43.
1989: Marcello Tonini; Lucio G Costa; Stefano M Candura; G Olibet; C A Rizzi; L Garlaschelli; Luigi Manzo
Interaction of the pyrethroid insecticides tetramethrin and cypermethrin with enteric cholinergic transmission in the guinea-pig.
Neurotoxicology 1989;10(4):707-15.
1988: Lucio G Costa; G Kaylor; S D Murphy
Muscarinic cholinergic binding sites on rat lymphocytes.
Immunopharmacology 1988;16(3):139-49.
1988: C R Stamper; Walter Balduini; S D Murphy; Lucio G Costa
Behavioral and biochemical effects of postnatal parathion exposure in the rat.
Neurotoxicology and teratology 1988;10(3):261-6.
1988: Lucio G Costa
Interactions of neurotoxicants with neurotransmitter systems.
Toxicology 1988;49(2-3):359-66.
1988: Lucio G Costa; G Olibet; S D Murphy
Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice.
Toxicology and applied pharmacology 1988;93(2):319-28.
1988: B E McDonald; Lucio G Costa; S D Murphy
Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates.
Toxicology letters 1988;40(1):47-56.
1987: Walter Balduini; S D Murphy; Lucio G Costa
Developmental changes in muscarinic receptor-stimulated phosphoinositide metabolism in rat brain.
The Journal of pharmacology and experimental therapeutics 1987;241(2):421-7.
1986: Lucio G Costa; G Kaylor; S D Murphy
Interaction of choline with muscarine receptor-stimulated phosphoinositide metabolism in the rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1986;334(4):536-9.
1986: Lucio G Costa; G Kaylor; S D Murphy
Carbachol- and norepinephrine-stimulated phosphoinositide metabolism in rat brain: effect of chronic cholinesterase inhibition.
The Journal of pharmacology and experimental therapeutics 1986;239(1):32-7.