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Max Costa
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Chemicals & Drugs
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33
Salnikow, Konstantin
20
Kluz, Thomas
20
Chen, Haobin
19
Zhitkovich, Anatoly
18
Huang, Chuanshu
16
Klein, Catherine
15
Li, Jingxia
14
Ke, Qingdong
12
Shi, Xianglin
11
Davidson, Todd
8
Broday, Limor
8
Zhang, Qunwei
7
Toniolo, Paolo
7
Voitkun, V
6
Yan, Yan
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All Publications
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2009: Xu Dazhong; Bai Jingxiang; Duan Qing; Costa Max; Dai Wei
Covalent modifications of histones during mitosis and meiosis.
Cell cycle (Georgetown, Tex.) 2009;8(22):3688-94.
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2009: Zhou Xue; Arita Adriana; Ellen Thomas P; Liu Xin; Bai Jingxiang; Rooney John P; Kurtz Adrienne D; Klein Catherine B; Dai Wei; Begley Thomas J; Costa Max
A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity.
Genomics 2009;94(5):294-307.
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2009: Li Qin; Ke Qingdong; Costa Max
Alterations of histone modifications by cobalt compounds.
Carcinogenesis 2009;30(7):1243-51.
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2009: Sun Hong; Zhou Xue; Chen Haobin; Li Qin; Costa Max
Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium.
Toxicology and applied pharmacology 2009;237(3):258-66.
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2009: Ellen Thomas P; Kluz Thomas; Harder Mark E; Xiong Judy; Costa Max
Heterochromatinization as a potential mechanism of nickel-induced carcinogenesis.
Biochemistry 2009;48(21):4626-32.
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2009: Zhou Xue; Li Qin; Arita Adriana; Sun Hong; Costa Max
Effects of nickel, chromate, and arsenite on histone 3 lysine methylation.
Toxicology and applied pharmacology 2009;236(1):78-84.
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2009: Chen Haobin; Costa Max
Iron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2009;22(1):191-6.
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2009: Ouyang Weiming; Zhang Dongyun; Li Jingxia; Verma Udit N; Costa Max; Huang Chuanshu
Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation.
Journal of cellular physiology 2009;218(1):205-14.
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2008: Duan Qing; Chen Haobin; Costa Max; Dai Wei
Phosphorylation of H3S10 blocks the access of H3K9 by specific antibodies and histone methyltransferase. Implication in regulating chromatin dynamics and epigenetic inheritance during mitosis.
The Journal of biological chemistry 2008;283(48):33585-90.
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2008: Zhou Xue; Sun Hong; Ellen Thomas P; Chen Haobin; Costa Max
Arsenite alters global histone H3 methylation.
Carcinogenesis 2008;29(9):1831-6.
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2008: Qu Qingshan; Li Xiaomei; An Feiyun; Jia Guang; Liu Lanzeng; Watanabe-Meserve Hiroko; Koenig Karen; Cohen Beverly; Costa Max; Roy Nirmal; Zhong Mianhua; Chen Lung Chi; Liu Suhua; Yan Lei
CrVI exposure and biomarkers: Cr in erythrocytes in relation to exposure and polymorphisms of genes encoding anion transport proteins.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(5):467-77.
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2008: Yang Yali; Bai Jingxiang; Shen Rulong; Brown Sharron A N; Komissarova Elena; Huang Ying; Jiang Ning; Alberts Gregory F; Costa Max; Lu Luo; Winkles Jeffrey A; Dai Wei
Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions.
Cancer research 2008;68(11):4077-85.
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2008: Ke Qingdong; Li Qin; Ellen Thomas P; Sun Hong; Costa Max
Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway.
Carcinogenesis 2008;29(6):1276-81.
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2008: Ke Qingdong; Ellen Thomas P; Costa Max
Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity.
Toxicology and applied pharmacology 2008;228(2):190-9.
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2008: Ellen Thomas P; Ke Qingdong; Zhang Ping; Costa Max
NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states.
Carcinogenesis 2008;29(1):2-8.
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2007: Zhang Ping; Tchou-Wong Kam-Meng; Costa Max
Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter.
Cancer research 2007;67(19):9125-33.
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2007: Uddin Ahmed N; Burns Fredric J; Rossman Toby G; Chen Haobin; Kluz Thomas; Costa Max
Dietary chromium and nickel enhance UV-carcinogenesis in skin of hairless mice.
Toxicology and applied pharmacology 2007;221(3):329-38.
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2007: Koshiji Minori; Kumamoto Kensuke; Morimura Keiichirou; Utsumi Yasufumi; Aizawa Michiko; Hoshino Masami; Ohki Shinji; Takenoshita Seiichi; Costa Max; Commes Thérèse; Piquemal David; Harris Curtis-C; Tchou-Wong Kam-Meng
Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity.
World journal of gastroenterology : WJG 2007;13(20):2803-10.
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2007: Zhang Dongyun; Li Jingxia; Wu Kangjian; Ouyang Weiming; Ding Jin; Liu Zheng-gang; Costa Max; Huang Chuanshu
JNK1, but not JNK2, is required for COX-2 induction by nickel compounds.
Carcinogenesis 2007;28(4):883-91.
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2007: Ke Qingdong; Davidson Todd; Kluz Thomas; Oller Adriana; Costa Max
Fluorescent tracking of nickel ions in human cultured cells.
Toxicology and applied pharmacology 2007;219(1):18-23.
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2006: Ding Jin; Zhang Xinhai; Li Jingxia; Song Lun; Ouyang Weiming; Zhang Dongyun; Xue Caifang; Costa Max; Meléndez J Andrés; Huang Chuanshu
Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKbeta/p65-dependent and IKKalpha- and p50-independent pathway.
The Journal of biological chemistry 2006;281(51):39022-32.
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2006: Ke Qingdong; Costa Max
Hypoxia-inducible factor-1 (HIF-1).
Molecular pharmacology 2006;70(5):1469-80.
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2006: Kang Gi Soo; Li Qin; Chen Haobin; Costa Max
Effect of metal ions on HIF-1alpha and Fe homeostasis in human A549 cells.
Mutation research 2006;610(1-2):48-55.
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2006: Chen Haobin; Costa Max
Effect of soluble nickel on cellular energy metabolism in A549 cells.
Experimental biology and medicine (Maywood, N.J.) 2006;231(9):1474-80.
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2006: Chen Haobin; Yan Yan; Davidson Todd L; Shinkai Yoichi; Costa Max
Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.
Cancer research 2006;66(18):9009-16.
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2006: Ke Qingdong; Li Jingxia; Ding Jin; Ding Min; Wang Liying; Liu Bingci; Costa Max; Huang Chuanshu
Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposure.
American journal of physiology. Lung cellular and molecular physiology 2006;291(2):L257-64.
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2006: Davidson Todd L; Chen Haobin; Di Toro Dominic M; D'Angelo Gisela; Costa Max
Soluble nickel inhibits HIF-prolyl-hydroxylases creating persistent hypoxic signaling in A549 cells.
Molecular carcinogenesis 2006;45(7):479-89.
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2006: Ke Qingdong; Davidson Todd; Chen Haobin; Kluz Thomas; Costa Max
Alterations of histone modifications and transgene silencing by nickel chloride.
Carcinogenesis 2006;27(7):1481-8.
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2006: Li Qin; Chen Haobin; Huang Xi; Costa Max
Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes.
Toxicology and applied pharmacology 2006;213(3):245-55.
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2006: Chen Haobin; Ke Qingdong; Kluz Thomas; Yan Yan; Costa Max
Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.
Molecular and cellular biology 2006;26(10):3728-37.
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2006: Costa Max; Klein Catherine B
Toxicity and carcinogenicity of chromium compounds in humans.
Critical reviews in toxicology 2006;36(2):155-63.
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2006: Wu Jing; Eckard Jonathan; Chen Haobin; Costa Max; Frenkel Krystyna; Huang Xi
Altered iron homeostasis involvement in arsenite-mediated cell transformation.
Free radical biology & medicine 2006;40(3):444-52.
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2006: Garrick Michael D; Singleton Steven T; Vargas Farida; Kuo H-C; Zhao Lin; Knöpfel Martin; Davidson Todd; Costa Max; Paradkar Prasad; Roth Jerome A; Garrick Laura M
DMT1: which metals does it transport?
Biological research 2006;39(1):79-85.
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2005: Costa Max; Davidson Todd L; Chen Haobin; Ke Qingdong; Zhang Ping; Yan Yan; Huang Chuanshu; Kluz Thomas
Nickel carcinogenesis: epigenetics and hypoxia signaling.
Mutation research 2005;592(1-2):79-88.
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2005: Davidson Todd; Chen Haobin; Garrick Michael D; D'Angelo Gisela; Costa Max
Soluble nickel interferes with cellular iron homeostasis.
Molecular and cellular biochemistry 2005;279(1-2):157-62.
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2005: Lu Haitian; Shi Xianglin; Costa Max; Huang Chuanshu
Carcinogenic effect of nickel compounds.
Molecular and cellular biochemistry 2005;279(1-2):45-67.
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2005: Ouyang Weiming; Li Jingxia; Shi Xianglin; Costa Max; Huang Chuanshu
Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression.
Molecular and cellular biochemistry 2005;279(1-2):35-43.
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2005: Li Jingxia; Tong Qiangsong; Shi Xianglin; Costa Max; Huang Chuanshu
ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells.
Molecular and cellular biochemistry 2005;279(1-2):25-33.
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2005: Chen Haobin; Davidson Todd; Singleton Steven; Garrick Michael D; Costa Max
Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells.
Toxicology and applied pharmacology 2005;206(3):275-87.
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2005: Ke Qingdong; Kluz Thomas; Costa Max
Down-regulation of the expression of the FIH-1 and ARD-1 genes at the transcriptional level by nickel and cobalt in the human lung adenocarcinoma A549 cell line.
International journal of environmental research and public health 2005;2(1):10-3.
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2004: Li Jingxia; Chen Haobin; Ke Qingdong; Feng Zhaohui; Tang Moon-Shong; Liu Bingci; Amin Shantu; Costa Max; Huang Chuanshu
Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells.
Molecular carcinogenesis 2004;40(2):104-15.
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2004: Zoroddu M A; Peana M; Kowalik-Jankowska T; Kozlowski H; Costa M
Nickel(II) binding to Cap43 protein fragments.
Journal of inorganic biochemistry 2004;98(6):931-9.
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2004: Davidson Todd; Kluz Thomas; Burns Fredric; Rossman Toby; Zhang Qunwei; Uddin Ahmed; Nadas Arthur; Costa Max
Exposure to chromium (VI) in the drinking water increases susceptibility to UV-induced skin tumors in hairless mice.
Toxicology and applied pharmacology 2004;196(3):431-7.
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2004: Zhao Jianhua; Chen Haobin; Davidson Todd; Kluz Thomas; Zhang Qunwei; Costa Max
Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway.
Toxicology and applied pharmacology 2004;196(3):404-9.
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2004: Li Jingxia; Chen Haobin; Tang Moon-Shong; Shi Xianglin; Amin Shantu; Desai Dhimant; Costa Max; Huang Chuanshu
PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells.
The Journal of cell biology 2004;165(1):77-86.
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2004: Li Jingxia; Dokka Sujatha; Wang Liying; Shi Xianglin; Castranova Vincent; Yan Yan; Costa Max; Huang Chuanshu
Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells.
Molecular and cellular biochemistry 2004;255(1-2):217-25.
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2004: Huang Chuanshu; Ke Qingdong; Costa Max; Shi Xianglin
Molecular mechanisms of arsenic carcinogenesis.
Molecular and cellular biochemistry 2004;255(1-2):57-66.
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2004: Caruso Robert P; Levinson Benjamin; Melamed Jonathan; Wieczorek Rosemary; Taneja Samir; Polsky David; Chang Caroline; Zeleniuch-Jacquotte Anne; Salnikow Konstantin; Yee Herman; Costa Max; Osman Iman
Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(1 Pt 1):222-7.
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2004: Li Jingxia; Davidson Gerard; Huang Yi; Jiang Bing-Hua; Shi Xianglin; Costa Max; Huang Chuanshu
Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells.
Cancer research 2004;64(1):94-101.
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2004: Zhao Jianhua; Yan Yan; Salnikow Konstantin; Kluz Thomas; Costa Max
Nickel-induced down-regulation of serpin by hypoxic signaling.
Toxicology and applied pharmacology 2004;194(1):60-8.
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2003: Davidson Todd; Salnikow Konstantin; Costa Max
Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel.
Molecular pharmacology 2003;64(6):1485-93.
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2003: Zhang Qunwei; Salnikow Konstantin; Kluz Thomas; Chen Lung Chi; Su Wei Cheng; Costa Max
Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A.
Toxicology and applied pharmacology 2003;192(3):201-11.
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2003: Yan Yan; Kluz Thomas; Zhang Ping; Chen Hao-bin; Costa Max
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure.
Toxicology and applied pharmacology 2003;190(3):272-7.
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2003: Salnikow Konstantin; Davidson Todd; Zhang Qunwei; Chen Lung Chi; Su Weichen; Costa Max
The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis.
Cancer research 2003;63(13):3524-30.
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2003: Costa Max; Yan Yan; Zhao Daoji; Salnikow Konstantin
Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling.
Journal of environmental monitoring : JEM 2003;5(2):222-3.
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2003: Salnikow Konstantin; Davidson Todd; Kluz Thomas; Chen Haobin; Zhou Daoji; Costa Max
GeneChip analysis of signaling pathways effected by nickel.
Journal of environmental monitoring : JEM 2003;5(2):206-9.
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2003: Feng Zhaohui; Hu Wenwei; Rom William N; Costa Max; Tang Moon-Shong
Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells.
Carcinogenesis 2003;24(4):771-8.
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2002: Cangul Hakan; Salnikow Konstantin; Yee Herman; Zagzag David; Commes Therese; Costa Max
Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.
Environmental health perspectives 2002;110 Suppl 5():783-8.
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2002: Salnikow Konstantin; Davidson Todd; Costa Max
The role of hypoxia-inducible signaling pathway in nickel carcinogenesis.
Environmental health perspectives 2002;110 Suppl 5():831-4.
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2002: Zoroddu Maria Antonietta; Schinocca Laura; Kowalik-Jankowska Teresa; Kozlowski Henryk; Salnikow Konstantin; Costa Max
Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4.
Environmental health perspectives 2002;110 Suppl 5():719-23.
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2002: Huang Chuanshu; Li Jingxia; Ke Qingdong; Leonard Stephen S; Jiang Bing-Hua; Zhong Xiao-Song; Costa Max; Castranova Vincent; Shi Xianglin
Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
Cancer research 2002;62(20):5689-97.
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2002: Costa Max
Molecular mechanisms of nickel carcinogenesis.
Biological chemistry 2002;383(6):961-7.
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2002: Costa Max; Salnikow Konstantin; Sutherland Jessica E; Broday Limor; Peng Wu; Zhang Qunwei; Kluz Thomas
The role of oxidative stress in nickel and chromate genotoxicity.
Molecular and cellular biochemistry 2002;234-235(1-2):265-75.
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2002: Zhang Qunwei; Kluz Thomas; Salnikow Konstantin; Costa Max
Comparison of the cytotoxicity, cellular uptake, and DNA-protein crosslinks induced by potassium chromate in lymphoblast cell lines derived from three different individuals.
Biological trace element research 2002;86(1):11-22.
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2002: Salnikow Konstantin; Kluz Thomas; Costa Max; Piquemal David; Demidenko Zoya N; Xie Keping; Blagosklonny Mikhail V
The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia.
Molecular and cellular biology 2002;22(6):1734-41.
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2002: Cangul H; Broday L; Salnikow K; Sutherland J; Peng W; Zhang Q; Poltaratsky V; Yee H; Zoroddu M A; Costa M
Molecular mechanisms of nickel carcinogenesis.
Toxicology letters 2002;127(1-3):69-75.
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2002: Cangul H; Salnikow K; Yee H; Zagzag D; Commes T; Costa M
Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis.
Cell biology and toxicology 2002;18(2):87-96.
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2001: Huang C; Li J; Costa M; Zhang Z; Leonard S S; Castranova V; Vallyathan V; Ju G; Shi X
Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide.
Cancer research 2001;61(22):8051-7.
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2001: Sutherland J E; Peng W; Zhang Q; Costa M
The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells.
Mutation research 2001;479(1-2):225-33.
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2001: Huang C; Li J; Ding M; Wang L; Shi X; Castranova V; Vallyathan V; Ju G; Costa M
Arsenic-induced NFkappaB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells.
Molecular and cellular biochemistry 2001;222(1-2):29-34.
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2001: Costa M; Sutherland J E; Peng W; Salnikow K; Broday L; Kluz T
Molecular biology of nickel carcinogenesis.
Molecular and cellular biochemistry 2001;222(1-2):205-11.
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2001: Huang C; Zhang Q; Li J; Shi X; Castranova V; Ju G; Costa M; Dong Z
Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo.
Molecular and cellular biochemistry 2001;222(1-2):141-7.
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2001: Huang C; Li J; Ding M; Costa M; Castranova V; Vallyathan V; Ju G; Shi X
Transactivation of RARE and GRE in the cellular response to arsenic.
Molecular and cellular biochemistry 2001;222(1-2):119-25.
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2001: Zoroddu M A; Kowalik-Jankowska T; Kozlowski H; Salnikow K; Costa M
Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR.
Journal of inorganic biochemistry 2001;84(1-2):47-54.
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2000: Salnikow K; Costa M; Figg W D; Blagosklonny M V
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.
Cancer research 2000;60(20):5630-4.
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2000: Salnikow K; Su W; Blagosklonny M V; Costa M
Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism.
Cancer research 2000;60(13):3375-8.
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2000: Zoroddu M A; Kowalik-Jankowska T; Kozlowski H; Molinari H; Salnikow K; Broday L; Costa M
Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail.
Biochimica et biophysica acta 2000;1475(2):163-8.
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2000: Sutherland J E; Zhitkovich A; Kluz T; Costa M
Rats retain chromium in tissues following chronic ingestion of drinking water containing hexavalent chromium.
Biological trace element research 2000;74(1):41-53.
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2000: Broday L; Peng W; Kuo M H; Salnikow K; Zoroddu M; Costa M
Nickel compounds are novel inhibitors of histone H4 acetylation.
Cancer research 2000;60(2):238-41.
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2000: Salnikow K; Blagosklonny M V; Ryan H; Johnson R; Costa M
Carcinogenic nickel induces genes involved with hypoxic stress.
Cancer research 2000;60(1):38-41.
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2000: Salnikow K; Costa M
Epigenetic mechanisms of nickel carcinogenesis.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2000;19(3):307-18.
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1999: Salnikow K; Kluz T; Costa M
Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression.
Toxicology and applied pharmacology 1999;160(2):127-32.
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1999: Salnikow K; An W G; Melillo G; Blagosklonny M V; Costa M
Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors.
Carcinogenesis 1999;20(9):1819-23.
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1999: Broday L; Cai J; Costa M
Nickel enhances telomeric silencing in Saccharomyces cerevisiae.
Mutation research 1999;440(2):121-30.
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1999: Broday L; Lee Y W; Costa M
5-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells.
Molecular and cellular biology 1999;19(4):3198-204.
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1998: Zhitkovich A; Voitkun V; Kluz T; Costa M
Utilization of DNA-protein cross-links as a biomarker of chromium exposure.
Environmental health perspectives 1998;106 Suppl 4():969-74.
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1998: Lee Y W; Broday L; Costa M
Effects of nickel on DNA methyltransferase activity and genomic DNA methylation levels.
Mutation research 1998;415(3):213-8.
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1998: Zhou D; Salnikow K; Costa M
Cap43, a novel gene specifically induced by Ni2+ compounds.
Cancer research 1998;58(10):2182-9.
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1998: Voitkun V; Zhitkovich A; Costa M
Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells.
Nucleic acids research 1998;26(8):2024-30.
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1998: Costa M
Carcinogenic metals.
Science progress 1998;81 ( Pt 4)():329-39.
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1997: Salnikow K; Wang S; Costa M
Induction of activating transcription factor 1 by nickel and its role as a negative regulator of thrombospondin I gene expression.
Cancer research 1997;57(22):5060-6.
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1997: Costa M
Toxicity and carcinogenicity of Cr(VI) in animal models and humans.
Critical reviews in toxicology 1997;27(5):431-42.
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1997: Costa M; Zhitkovich A; Harris M; Paustenbach D; Gargas M
DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells.
Journal of toxicology and environmental health 1997;50(5):433-49.
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1997: Klein C B; Costa M
DNA methylation, heterochromatin and epigenetic carcinogens.
Mutation research 1997;386(2):163-80.
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1997: Klein C B; Costa M
DNA methylation and gene expression: introduction and overview.
Mutation research 1997;386(2):103-5.
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1996: Costa M; Zhitkovich A; Toniolo P; Taioli E; Popov T; Lukanova A
Monitoring human lymphocytic DNA-protein cross-links as biomarkers of biologically active doses of chromate.
Environmental health perspectives 1996;104 Suppl 5():917-9.
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1996: Kitahara J; Yamanaka K; Kato K; Lee Y W; Klein C B; Costa M
Mutagenicity of cobalt and reactive oxygen producers.
Mutation research 1996;370(3-4):133-40.
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1996: Costa M; Bellosta P; Basilico C
Cleavage and release of a soluble form of the receptor tyrosine kinase ARK in vitro and in vivo.
Journal of cellular physiology 1996;168(3):737-44.
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1996: Costa M; Zhitkovich A; Gargas M; Paustenbach D; Finley B; Kuykendall J; Billings R; Carlson T J; Wetterhahn K; Xu J; Patierno S; Bogdanffy M
Interlaboratory validation of a new assay for DNA-protein crosslinks.
Mutation research 1996;369(1-2):13-21.
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1996: Zhitkovich A; Voitkun V; Costa M
Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: importance of trivalent chromium and the phosphate group.
Biochemistry 1996;35(22):7275-82.
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1996: Dowjat W K; Huang X; Cosentino S; Costa M
Peroxidase deficiency of nickel-transformed hamster cells correlates with their increased resistance to cytotoxicity of peroxides.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1996;9(2):151-6.
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1996: Lukanova A; Toniolo P; Zhitkovich A; Nikolova V; Panev T; Popov T; Taioli E; Costa M
Occupational exposure to Cr(VI): comparison between chromium levels in lymphocytes, erythrocytes, and urine.
International archives of occupational and environmental health 1996;69(1):39-44.
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1995: Taioli E; Zhitkovich A; Kinney P; Udasin I; Toniolo P; Costa M
Increased DNA-protein crosslinks in lymphocytes of residents living in chromium-contaminated areas.
Biological trace element research 1995;50(3):175-80.
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1995: Huang X; Kitahara J; Zhitkovich A; Dowjat K; Costa M
Heterochromatic proteins specifically enhance nickel-induced 8-oxo-dG formation.
Carcinogenesis 1995;16(8):1753-9.
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1995: Lee Y W; Klein C B; Kargacin B; Salnikow K; Kitahara J; Dowjat K; Zhitkovich A; Christie N T; Costa M
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens.
Molecular and cellular biology 1995;15(5):2547-57.
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1995: Zhitkovich A; Voitkun V; Costa M
Glutathione and free amino acids form stable complexes with DNA following exposure of intact mammalian cells to chromate.
Carcinogenesis 1995;16(4):907-13.
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1995: Bellosta P; Costa M; Lin D A; Basilico C
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding.
Molecular and cellular biology 1995;15(2):614-25.
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1994: Salnikow K; Gao M; Voitkun V; Huang X; Costa M
Altered oxidative stress responses in nickel-resistant mammalian cells.
Cancer research 1994;54(24):6407-12.
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1994: Klein C B; Kargacin B; Su L; Cosentino S; Snow E T; Costa M
Metal mutagenesis in transgenic Chinese hamster cell lines.
Environmental health perspectives 1994;102 Suppl 3():63-7.
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1994: Zhuang Z; Costa M
Development of an 125I-postlabeling assay as a simple, rapid, and sensitive index of DNA-protein cross-links.
Environmental health perspectives 1994;102 Suppl 3():301-4.
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1994: Lin X; Costa M
Transformation of human osteoblasts to anchorage-independent growth by insoluble nickel particles.
Environmental health perspectives 1994;102 Suppl 3():289-92.
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1994: Huang X; Zhuang Z; Frenkel K; Klein C B; Costa M
The role of nickel and nickel-mediated reactive oxygen species in the mechanism of nickel carcinogenesis.
Environmental health perspectives 1994;102 Suppl 3():281-4.
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1994: Voitkun V; Zhitkovich A; Costa M
Complexing of amino acids to DNA by chromate in intact cells.
Environmental health perspectives 1994;102 Suppl 3():251-5.
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1994: Costa M; Salnikow K; Cosentino S; Klein C B; Huang X; Zhuang Z
Molecular mechanisms of nickel carcinogenesis.
Environmental health perspectives 1994;102 Suppl 3():127-30.
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1994: Zhuang Z; Huang X; Costa M
Protein oxidation and amino acid-DNA crosslinking by nickel compounds in intact cultured cells.
Toxicology and applied pharmacology 1994;126(2):319-25.
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1994: Costa M; Zhuang Z; Huang X; Cosentino S; Klein C B; Salnikow K
Molecular mechanisms of nickel carcinogenesis.
The Science of the total environment 1994;148(2-3):191-9.
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1994: Lin X; Dowjat W K; Costa M
Nickel-induced transformation of human cells causes loss of the phosphorylation of the retinoblastoma protein.
Cancer research 1994;54(10):2751-4.
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1994: Huang X; Klein C B; Costa M
Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein.
Carcinogenesis 1994;15(3):545-8.
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1994: Taioli E; Kinney P; Zhitkovich A; Fulton H; Voitkun V; Cosma G; Frenkel K; Toniolo P; Garte S; Costa M
Application of reliability models to studies of biomarker validation.
Environmental health perspectives 1994;102(3):306-9.
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1994: Salnikow K; Cosentino S; Klein C; Costa M
Loss of thrombospondin transcriptional activity in nickel-transformed cells.
Molecular and cellular biology 1994;14(1):851-8.
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1993: Costa M; Zhitkovich A; Taioli E; Toniolo P
Preliminary report on a simple new assay for DNA-protein cross-links as a biomarker of exposures experienced by welders.
Journal of toxicology and environmental health 1993;40(2-3):217-22.
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1993: Kargacin B; Klein C B; Costa M
Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus.
Mutation research 1993;300(1):63-72.
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1993: Huang X; Frenkel K; Klein C B; Costa M
Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence.
Toxicology and applied pharmacology 1993;120(1):29-36.
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1993: Costa M; Zhitkovich A; Toniolo P
DNA-protein cross-links in welders: molecular implications.
Cancer research 1993;53(3):460-3.
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1993: Toniolo P; Zhitkovich A; Costa M
Development and utilization of a new simple assay for DNA-protein crosslinks as a biomarker of exposure to welding fumes.
International archives of occupational and environmental health 1993;65(1 Suppl):S87-9.
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1993: Cohen M D; Kargacin B; Klein C B; Costa M
Mechanisms of chromium carcinogenicity and toxicity.
Critical reviews in toxicology 1993;23(3):255-81.
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1993: Costa M
Molecular targets of nickel and chromium in human and experimental systems.
Scandinavian journal of work, environment & health 1993;19 Suppl 1():71-4.
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1992: Salnikow K; Zhitkovich A; Costa M
Analysis of the binding sites of chromium to DNA and protein in vitro and in intact cells.
Carcinogenesis 1992;13(12):2341-6.
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1992: Lin X; Zhuang Z; Costa M
Analysis of residual amino acid--DNA crosslinks induced in intact cells by nickel and chromium compounds.
Carcinogenesis 1992;13(10):1763-8.
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1992: Cohen M D; Klein C B; Costa M
Forward mutations and DNA-protein crosslinks induced by ammonium metavanadate in cultured mammalian cells.
Mutation research 1992;269(1):141-8.
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1992: Zhitkovich A; Costa M
A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo.
Carcinogenesis 1992;13(8):1485-9.
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1992: Wang X W; Lin X; Klein C B; Bhamra R K; Lee Y W; Costa M
A conserved region in human and Chinese hamster X chromosomes can induce cellular senescence of nickel-transformed Chinese hamster cell lines.
Carcinogenesis 1992;13(4):555-61.
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1991: Chen Y; Cohen M D; Snow E T; Costa M
Alteration in restriction enzyme digestion patterns detects DNA--protein complexes induced by chromate.
Carcinogenesis 1991;12(9):1575-80.
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1991: Lin X H; Sugiyama M; Costa M
Differences in the effect of vitamin E on nickel sulfide or nickel chloride-induced chromosomal aberrations in mammalian cells.
Mutation research 1991;260(2):159-64.
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1991: Coogan T P; Motz J; Snyder C A; Squibb K S; Costa M
Differential DNA-protein crosslinking in lymphocytes and liver following chronic drinking water exposure of rats to potassium chromate.
Toxicology and applied pharmacology 1991;109(1):60-72.
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1991: Costa M
DNA-protein complexes induced by chromate and other carcinogens.
Environmental health perspectives 1991;92():45-52.
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1991: Coogan T P; Squibb K S; Motz J; Kinney P L; Costa M
Distribution of chromium within cells of the blood.
Toxicology and applied pharmacology 1991;108(1):157-66.
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1991: Miller C A; Cohen M D; Costa M
Complexing of actin and other nuclear proteins to DNA by cis-diamminedichloroplatinum(II) and chromium compounds.
Carcinogenesis 1991;12(2):269-76.
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1991: Klein C B; Conway K; Wang X W; Bhamra R K; Lin X H; Cohen M D; Annab L; Barrett J C; Costa M
Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control.
Science (New York, N.Y.) 1991;251(4995):796-9.
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1991: Wang X W; Costa M
Changes in protein phosphorylation in wild-type and nickel-resistant cells and their involvement in morphological elongation.
Biology of metals 1991;4(4):201-6.
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1990: Costa M
Analysis of DNA-protein complexes induced by chemical carcinogens.
Journal of cellular biochemistry 1990;44(3):127-35.
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1990: Cohen M D; Miller C A; Xu L S; Snow E T; Costa M
A blotting method for monitoring the formation of chemically induced DNA-protein complexes.
Analytical biochemistry 1990;186(1):1-7.
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1990: Miller C A; Costa M
Immunodetection of DNA-protein crosslinks by slot blotting.
Mutation research 1990;234(2):97-106.
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1989: Conway K; Costa M
Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells.
Cancer research 1989;49(21):6032-8.
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1989: Imbra R J; Wang X W; Costa M
Characterization of a nickel resistant mouse cell line.
Biological trace element research 1989;21():97-103.
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1989: Conway K; Costa M
The involvement of heterochromatic damage in nickel-induced transformation.
Biological trace element research 1989;21():437-44.
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1989: Coogan T P; Latta D M; Imbra R J; Costa M
Effect of nickel(II) on DNA-protein interactions.
Biological trace element research 1989;21():13-21.
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1989: Costa M
Perspectives on the mechanism of nickel carcinogenesis gained from models of in vitro carcinogenesis.
Environmental health perspectives 1989;81():73-6.
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1989: Miller C A; Costa M
Immunological detection of DNA-protein complexes induced by chromate.
Carcinogenesis 1989;10(4):667-72.
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1989: Coogan T P; Latta D M; Snow E T; Costa M
Toxicity and carcinogenicity of nickel compounds.
Critical reviews in toxicology 1989;19(4):341-84.
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1989: Miller C A; Costa M
Analysis of proteins cross-linked to DNA after treatment of cells with formaldehyde, chromate, and cis-diamminedichloroplatinum(II).
Molecular toxicology 1989;2(1):11-26.
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1988: Wang X W; Imbra R J; Costa M
Characterization of mouse cell lines resistant to nickel(II) ions.
Cancer research 1988;48(23):6850-4.
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1988: Zelikoff J T; Li J H; Hartwig A; Wang X W; Costa M; Rossman T G
Genetic toxicology of lead compounds.
Carcinogenesis 1988;9(10):1727-32.
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1988: Christie N T; Sen P; Costa M
Chromosomal alterations in cell lines derived from mouse rhabdomyosarcomas induced by crystalline nickel sulfide.
Biology of metals 1988;1(1):43-50.
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1988: Miller C A; Costa M
Characterization of DNA-protein complexes induced in intact cells by the carcinogen chromate.
Molecular carcinogenesis 1988;1(2):125-33.
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