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Carl Cotman

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Shikha Snigdha; S Weintraub; Sherry L Willis; Marylin Albert; Norbert J Fortin; Norton W Milgram; Carl W Cotman
A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap.
Nicole C Berchtold; Paul D. Coleman; David H Cribbs; Daniel L Gillen; Joseph Rogers; Carl W Cotman
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease.
Liqi Tong; David H Cribbs; Enikö A Kramár; Gary Lynch; G Aleph Prieto; Erica D Smith; Carl W Cotman
Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase.

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2013: Shikha Snigdha; S Weintraub; Sherry L Willis; Marylin Albert; Norbert J Fortin; Norton W Milgram; Carl W Cotman
A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap.
Neurobiology of aging 2013;34(7):1891-901.
2013: Nicole C Berchtold; Paul D. Coleman; David H Cribbs; Daniel L Gillen; Joseph Rogers; Carl W Cotman
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease.
Neurobiology of aging 2013;34(6):1653-61.
2012: Liqi Tong; David H Cribbs; Enikö A Kramár; Gary Lynch; G Aleph Prieto; Erica D Smith; Carl W Cotman
Brain-derived neurotrophic factor-dependent synaptic plasticity is suppressed by interleukin-1β via p38 mitogen-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(49):17714-24.
2012: Kwang-Mook Jung; Vitaly Vasilevko; Sevil Yasar; Giuseppe Astarita; Carl W Cotman; David H Cribbs; Elizabeth Head; Daniele Piomelli
An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease.
Neurobiology of aging 2012;33(8):1522-32.
2012: Sean P Deeny; Malcolm Dick; Kathryn Nichol; Stephen M Roth; Jeanna Winchester; Joseph C Wu; Carl W Cotman
Cardiovascular fitness is associated with altered cortical glucose metabolism during working memory in ɛ4 carriers.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(4):352-6.
2012: Sandra Bond Chapman; Carl W Cotman; Howard M Fillit; Michela Gallagher; Christopher H van Dyck
Clinical trials: new opportunities.
The journals of gerontology. Series A, Biological sciences and medical sciences 2012;67(7):773-80.
2012: Margaret Fahnestock; Elizabeth Head; Monica Marchese; Bernadeta Michalski; William N Milgram; Viorela Pop; Carl W Cotman
BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog.
Neurobiology of aging 2012;33(3):546-54.
2012: Shikha Snigdha; Joseph A Araujo; Lori-Ann Christie; Christina de Rivera; Norton W Milgram; Carl W Cotman
Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs.
Age (Dordrecht, Netherlands) 2012;34(1):67-73.
2012: S Snigdha; Daniele Piomelli; Giuseppe Astarita; Carl W Cotman
Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain.
Neuroscience 2012;202():326-33.
2012: Sabrina K Segal; Carl W Cotman; Lawrence F Cahill
Exercise-induced noradrenergic activation enhances memory consolidation in both normal aging and patients with amnestic mild cognitive impairment.
Journal of Alzheimer's disease : JAD 2012;32(4):1011-8.
2012: David H Cribbs; Victoria M Perreau; Joseph Rogers; Andrea J Tenner; Nicole C Berchtold; Paul D Coleman; Carl W Cotman
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study.
Journal of neuroinflammation 2012;9():179.
2012: Viorela Pop; Christa M Studzinski; Adam M Weidner; Nicole C Berchtold; Charles G Glabe; Elizabeth Head; M Paul Murphy; Carl W Cotman
Aβ aggregation profiles and shifts in APP processing favor amyloidogenesis in canines.
Neurobiology of aging 2012;33(1):108-20.
2011: Adam C Naj; Gyungah Jun; Gary Beecham; Li-San Wang; Badri Narayan Vardarajan; Jacqueline Buros; Paul J Gallins; Joseph Buxbaum; Gail P Jarvik; Paul K Crane; Eric B Larson; Thomas D Bird; Bradley F Boeve; Neill R Graff-Radford; Philip L De Jager; Denis Evans; Julie A Schneider; Minerva M Carrasquillo; Nilufer Ertekin-Taner; Steven G Younkin; Carlos Cruchaga; John S K Kauwe; Petra Nowotny; Patricia Kramer; John Hardy; Matthew Huentelman; Amanda Myers; M. Michael Barmada; F Yesim Demirci; Clinton T Baldwin; Robert C Green; Ekaterina Rogaeva; Steven E Arnold; Robert C Barber; Thomas Beach; Eileen H Bigio; James D Bowen; Adam Boxer; James R Burke; Nigel J Cairns; Chris S Carlson; Regina M Carney; Steven L Carroll; Helena C Chui; David G Clark; Jason Corneveaux; Carl W Cotman; Jeffrey L Cummings; Charles DeCarli; Steven T DeKosky; Ramon Diaz-Arrastia; Malcolm Dick; dennis dickson; William G Ellis; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Matthew P Frosch; Douglas Galasko; Mary Ganguli; Marla Gearing; Daniel Geschwind; Bernardino Ghetti; John Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; John H Growdon; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence Honig; Christine M Hulette; Bradley T Hyman; Gregory A Jicha; Lee-Way Jin; Nancy Johnson; Jason Karlawish; Anna Karydas; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; James J Lah; Allan Levey; Andrew P Lieberman; Oscar L Lopez; Wendy J Mack; Daniel C Marson; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua Miller; Joseph E Parisi; Daniel P Perl; Elaine Peskind; Ronald C. Petersen; Wayne W Poon; Joseph F Quinn; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; John M Ringman; Erik D Roberson; Roger N Rosenberg; Mary Sano; Lon S Schneider; William Seeley; Michael L Shelanski; Michael Slifer; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Vivianna M Van Deerlin; Harry V Vinters; Jean Paul Vonsattel; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Laura B Cantwell; Beth A Dombroski; Duane Beekly; Kathryn L Lunetta; Eden R Martin; M Ilyas Kamboh; Andrew J Saykin; Eric Reiman; David A Bennett; John C Morris; Thomas J Montine; Alison Goate; Deborah Blacker; Debby W Tsuang; Hakon Hakonarson; Walter A Kukull; Tatiana M Foroud; Jonathan L Haines; Richard Mayeux; Margaret Pericak-Vance; Lindsay A Farrer; Peter St George-Hyslop; Gerard D Schellenberg
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Nature genetics 2011;43(5):436-41.
2011: Wayne W Poon; Mathew Blurton-Jones; Christina H Tu; Leila M Feinberg; Meredith A Chabrier; Joe W Harris; Noo Li Jeon; Carl W Cotman
β-Amyloid impairs axonal BDNF retrograde trafficking.
Neurobiology of aging 2011;32(5):821-33.
2011: Giuseppe Astarita; Carl W Cotman; David H Cribbs; Nicholas V Dipatrizio; Elizabeth Head; Kwang-Mook Jung; Sarah K Martin; Vitaly Vasilevko; Daniele Piomelli
Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease.
PloS one 2011;6(10):e24777.
2011: Shikha Snigdha; Giuseppe Astarita; Nicole Berchtold; Daniele Piomelli; Tommy Saing; Carl W Cotman
Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain.
PloS one 2011;6(9):e24652.
2011: Paul A Adlard; Christie Engesser-Cesar; Carl W Cotman
Mild stress facilitates learning and exercise improves retention in aged mice.
Experimental gerontology 2011;46(1):53-9.
2010: Vitaly Vasilevko; Viorela Pop; Hyun Jin Kim; Tommy Saing; Charles C Glabe; Saskia Milton; Edward G Barrett; Carl W Cotman; David H Cribbs; Elizabeth Head
Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta.
Neurobiology of disease 2010;39(3):301-10.
2010: Viorela Pop; Elizabeth Head; Mary-Ann Hill; Dan Gillen; Nicole C Berchtold; Bruce A Muggenburg; Norton W Milgram; M Paul Murphy; Carl W Cotman
Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(29):9831-9.
2010: Nicole C Berchtold; N Castello; Carl W Cotman
Exercise and time-dependent benefits to learning and memory.
Neuroscience 2010;167(3):588-97.
2010: Vivianna M Van Deerlin; Patrick M A Sleiman; Maria Martinez-Lage; Alice Chen-Plotkin; Li-San Wang; Neill R Graff-Radford; dennis dickson; Rosa Rademakers; Bradley F Boeve; Murray Grossman; Steven E Arnold; D M A Mann; Stuart M Pickering-Brown; Harro Seelaar; Peter Heutink; John C van Swieten; Jill R Murrell; Bernardino Ghetti; Salvatore Spina; Jordan Grafman; John R Hodges; Maria Grazia Spillantini; Sid Gilman; Andrew P Lieberman; Jeffrey A Kaye; Randall L Woltjer; Eileen H Bigio; Marsel Mesulam; Safa Al-Sarraj; Claire Troakes; Roger N Rosenberg; Charles L White; Isidro Ferrer; Albert Lladó; Manuela Neumann; Hans A Kretzschmar; Christine Marie Hulette; Kathleen A Welsh-Bohmer; Bruce L Miller; Ainhoa Alzualde; Adolfo Lopez de Munain; Ann C McKee; Marla Gearing; Allan Levey; James J Lah; John Hardy; Jonathan D Rohrer; Tammaryn Lashley; Ian R A Mackenzie; Howard H Feldman; Ronald L Hamilton; Steven T DeKosky; Julie van der Zee; Samir Kumar-Singh; Christine Van Broeckhoven; Richard Mayeux; Jean Paul G Vonsattel; Juan C Troncoso; Jillian J Kril; John B J Kwok; Glenda M Halliday; Thomas D Bird; Paul Geoffrey Ince; Pamela J Shaw; Nigel J Cairns; John C Morris; Catriona Ann McLean; Charles DeCarli; William G Ellis; Stefanie H Freeman; Matthew P Frosch; John H Growdon; Daniel P Perl; Mary Sano; David A Bennett; Julie A Schneider; Thomas Beach; Eric Reiman; Bryan Woodruff; Jeffrey L Cummings; Harry V Vinters; Carol A Miller; Helena C Chui; Irina Alafuzoff; Päivi Hartikainen; Danielle Seilhean; Douglas Galasko; Eliezer Masliah; Carl W Cotman; M Teresa Tuñón; M Cristina Caballero Martínez; David G Munoz; Steven L Carroll; Daniel Marson; Peter F Riederer; Nenad Bogdanovic; Gerard D Schellenberg; Hakon Hakonarson; John Q Trojanowski; Virginia M-Y Lee
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Nature genetics 2010;42(3):234-9.
2010: Giuseppe Astarita; Kwang-Mook Jung; Nicole C Berchtold; Vinh Q Nguyen; Daniel L Gillen; Elizabeth Head; Carl W Cotman; Daniele Piomelli
Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease.
PloS one 2010;5(9):e12538.
2010: Pinar E Coskun; Joanne Wyrembak; Olga Derbereva; Goar Melkonian; Eric Doran; Ira T Lott; Elizabeth Head; Carl W Cotman; Douglas C Wallace
Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia.
Journal of Alzheimer's disease : JAD 2010;20 Suppl 2():S293-310.
2009: Lori-Ann Christie; Wycliffe O Opii; Elizabeth Head; Joseph Araujo; Christina de Rivera; Norton W Milgram; Carl W Cotman
Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.
Experimental gerontology 2009;44(12):752-9.
2009: Munjal M Acharya; Lori-Ann Christie; Mary L Lan; Peter J Donovan; Carl W Cotman; John R Fike; Charles L Limoli
Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):19150-5.
2009: Elizabeth Head; Vidya N Nukala; Kristina A Fenoglio; B A Muggenburg; Carl W Cotman; Patrick G Sullivan
Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging.
Experimental neurology 2009;220(1):171-6.
2009: Kathryn Nichol; Sean P Deeny; Joseph Seif; Kevin Camaclang; Carl W Cotman
Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009;5(4):287-94.
2009: Anne Taylor; Nicole C Berchtold; Victoria M Perreau; Christina H Tu; Noo Li Jeon; Carl W Cotman
Axonal mRNA in uninjured and regenerating cortical mammalian axons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(15):4697-707.
2009: Jiangang Long; Feng Gao; Liqi Tong; Carl W Cotman; Bruce N Ames; Jiankang Liu
Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.
Neurochemical research 2009;34(4):755-63.
2008: Carl W Cotman; Elizabeth Head
The canine (dog) model of human aging and disease: dietary, environmental and immunotherapy approaches.
Journal of Alzheimer's disease : JAD 2008;15(4):685-707.
2008: Lori-Ann Christie; Richard C Saunders; Danuta M Kowalska; William A MacKay; Elizabeth Head; Carl W Cotman
Rhinal and dorsolateral prefrontal cortex lesions produce selective impairments in object and spatial learning and memory in canines.
The Journal of comparative neurology 2008;511(2):257-70.
2008: Lisa J Bain; Kathy Jedrziewski; Marcelle Morrison-Bogorad; Marilyn S Albert; Carl W Cotman; Hugh Hendrie; John Q Trojanowski
Healthy brain aging: a meeting report from the Sylvan M. Cohen Annual Retreat of the University of Pennsylvania Institute on Aging.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(6):443-6.
2008: Nicole C Berchtold; David H Cribbs; Paul D. Coleman; Joseph Rogers; Elizabeth Head; Ronald Kim; Thomas Beach; Carol Miller; Juan C Troncoso; John Q Trojanowski; H Ronald Zielke; Carl W Cotman
Gene expression changes in the course of normal brain aging are sexually dimorphic.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15605-10.
2008: Liqi Tong; Robert Balazs; Rungtip Soiampornkul; Wipawan Thangnipon; Carl W Cotman
Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction.
Neurobiology of aging 2008;29(9):1380-93.
2008: Anna Parachikova; K E Nichol; Carl W Cotman
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition.
Neurobiology of disease 2008;30(1):121-9.
2008: Xuesen Li; Zhongbo Liu; Cheng Luo; Haiqun Jia; Lijuan Sun; Bei Hou; Weili Shen; Lester Packer; Carl W Cotman; Jiankang Liu
Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction.
Free radical biology & medicine 2008;44(7):1465-74.
2008: Monica M Siegenthaler; Nicole C Berchtold; Carl W Cotman; Hans S Keirstead
Voluntary running attenuates age-related deficits following SCI.
Experimental neurology 2008;210(1):207-16.
2008: Rungtip Soiampornkul; Liqi Tong; Wipawan Thangnipon; Robert Balazs; Carl W Cotman
Interleukin-1beta interferes with signal transduction induced by neurotrophin-3 in cortical neurons.
Brain research 2008;1188():189-97.
2008: Kathryn E Nichol; Wayne W Poon; Anna I Parachikova; David H Cribbs; Charles G Glabe; Carl W Cotman
Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid.
Journal of neuroinflammation 2008;5():13.
2008: W Shen; K Liu; C Tian; L Yang; X Li; J Ren; L Packer; Carl W Cotman; J Liu
R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes.
Diabetologia 2008;51(1):165-74.
2008: Christina T Siwak-Tapp; Elizabeth Head; Bruce A Muggenburg; Norton W Milgram; Carl W Cotman
Region specific neuron loss in the aged canine hippocampus is reduced by enrichment.
Neurobiology of aging 2008;29(1):39-50.
2008: Wycliffe O Opii; Gururaj Joshi; Elizabeth Head; Norton W Milgram; Bruce A Muggenburg; Klein Jon; William M Pierce; Carl W Cotman; D Allan Butterfield
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.
Neurobiology of aging 2008;29(1):51-70.
2007: Kathryn E Nichol; Anna I Parachikova; Carl W Cotman
Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse.
Behavioural brain research 2007;184(2):124-32.
2007: Anna Parachikova; Michael G Agadjanyan; David H Cribbs; Mathew Blurton-Jones; V Perreau; Joseph Rogers; Thomas Beach; Carl W Cotman
Inflammatory changes parallel the early stages of Alzheimer disease.
Neurobiology of aging 2007;28(12):1821-33.
2007: Anna Parachikova; Carl W Cotman
Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease.
Neurobiology of disease 2007;28(2):143-53.
2007: Carl W Cotman; Nicole C Berchtold; Lori-Ann Christie
Exercise builds brain health: key roles of growth factor cascades and inflammation.
Trends in neurosciences 2007;30(9):464-72.
2007: Christina T Siwak-Tapp; Elizabeth Head; Bruce A Muggenburg; Norton W Milgram; Carl W Cotman
Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function.
Neurobiology of learning and memory 2007;88(2):249-59.
2007: Fulvio Celsi; M Svedberg; C Unger; Carl W Cotman; Maria Teresa Carrì; Ole Petter Ottersen; agneta nordberg; Reidun Torp
Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.
Neurobiology of disease 2007;26(2):342-52.
2007: Carl W Cotman; Nicole C Berchtold
Physical activity and the maintenance of cognition: learning from animal models.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2007;3(2 Suppl):S30-7.
2007: Christie Engesser-Cesar; Ronaldo M Ichiyama; Amber L Nefas; Mary Ann Hill; V Reggie Edgerton; Carl W Cotman; Aileen J Anderson
Wheel running following spinal cord injury improves locomotor recovery and stimulates serotonergic fiber growth.
The European journal of neuroscience 2007;25(7):1931-9.
2007: Lori-Ann Christie; Joseph H Su; Christina H Tu; Malcolm Dick; Jun Zhou; Carl W Cotman
Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains.
Neurobiology of disease 2007;26(1):165-73.
2007: Christie Engesser-Cesar; Aileen J Anderson; Carl W Cotman
Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord.
Neuroscience 2007;144(3):1033-44.
2007: Seog Woo Rhee; Anne Taylor; David H Cribbs; Carl W Cotman; Noo Li Jeon
External force-assisted cell positioning inside microfluidic devices.
Biomedical microdevices 2007;9(1):15-23.
2007: Joseph Harris; Hyuna Lee; Behrad Vahidi; Cristina Tu; David H Cribbs; Carl W Cotman; Noo Li Jeon
Non-plasma bonding of PDMS for inexpensive fabrication of microfluidic devices.
Journal of visualized experiments : JoVE 2007;(9):410.
2007: Joseph Harris; Hyuna Lee; Behrad Vahidi; Christina Tu; David H Cribbs; Noo Li Jeon; Carl W Cotman
Fabrication of a microfluidic device for the compartmentalization of neuron soma and axons.
Journal of visualized experiments : JoVE 2007;(7):261.
2007: Joseph Harris; Hyuna Lee; Christina Tu Tu; David H Cribbs; Carl W Cotman; Noo Li Jeon
Preparing e18 cortical rat neurons for compartmentalization in a microfluidic device.
Journal of visualized experiments : JoVE 2007;(8):305.
2007: Rakez Kayed; Elizabeth Head; Floyd Sarsoza; Tommy Saing; Carl W Cotman; Mihaela Necula; Lawrence Margol; Jessica Wu; Leonid Breydo; Jennifer L Thompson; Suhail Rasool; Tatyana Gurlo; Peter Butler; Charles G Glabe
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers.
Molecular neurodegeneration 2007;2():18.
2007: Lihong Jia; Zhongbo Liu; Lijuan Sun; Sheldon Miller; Bruce N Ames; Carl W Cotman; Jiankang Liu
Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid.
Investigative ophthalmology & visual science 2007;48(1):339-48.
2007: Edward H Sharman; Stephen C Bondy; Kaizhi G Sharman; Debomoy K Lahiri; Carl W Cotman; Victoria M Perreau
Effects of melatonin and age on gene expression in mouse CNS using microarray analysis.
Neurochemistry international 2007;50(2):336-44.
2007: Victoria M Perreau; Stephen C Bondy; Carl W Cotman; Kaizhi G Sharman; Edward H Sharman
Melatonin treatment in old mice enables a more youthful response to LPS in the brain.
Journal of neuroimmunology 2007;182(1-2):22-31.
2006: Javier Carrasco; P Adlard; Carl W Cotman; Albert Quintana; Milena Penkowa; F Xu; William E Van Nostrand; Juan Hidalgo
Metallothionein-I and -III expression in animal models of Alzheimer disease.
Neuroscience 2006;143(4):911-22.
2006: Charles Chan; Brian E Moore; Carl W Cotman; Hideyuki Okano; Rosemarie Tavares; Virginia Hovanesian; Halit Pinar; Conrad E Johanson; Clive Svendsen; Edward G Stopa
Musashi1 antigen expression in human fetal germinal matrix development.
Experimental neurology 2006;201(2):515-8.
2006: Charles Chubb; Yoshiyuki Inagaki; Phillip Sheu; Brian John Cummings; Andrea Wasserman; Elizabeth Head; Carl W Cotman
BioVision: an application for the automated image analysis of histological sections.
Neurobiology of aging 2006;27(10):1462-76.
2006: Christa M Studzinski; Lori-Ann Christie; Joseph Araujo; W McIntyre Burnham; Elizabeth Head; Carl W Cotman; Norton W Milgram
Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia.
Neurobiology of learning and memory 2006;86(2):197-204.
2006: Elizabeth Head; Edward G Barrett; Michael Murphy; Pritam Das; Mihaela Nistor; Floyd Sarsoza; Charles C Glabe; Rakez Kayed; Saskia Milton; Vitaly Vasilevko; Norton W Milgram; Michael G Agadjanyan; David H Cribbs; Carl W Cotman
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta.
Vaccine 2006;24(15):2824-34.
2006: Rod Dishman; Hans-Rudolf Berthoud; Frank W Booth; Carl W Cotman; V Reggie Edgerton; Monika R Fleshner; Simon C Gandevia; Fernando Gomez-Pinilla; Benjamin N Greenwood; Charles H Hillman; Arthur F Kramer; Barry E Levin; Timothy H Moran; Amelia A Russo-Neustadt; John D Salamone; Jacqueline D Van Hoomissen; Charles E Wade; David A York; Michael Zigmond
Neurobiology of exercise.
Obesity (Silver Spring, Md.) 2006;14(3):345-56.
2006: Po Lu; Donna A Masterman; Ruth Mulnard; Carl W Cotman; Bruce L Miller; Kristine Yaffe; Erin Reback; Verna Porter; Ronald S Swerdloff; Jeffrey L Cummings
Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men.
Archives of neurology 2006;63(2):177-85.
2005: Philip Roudebush; Steven C Zicker; Carl W Cotman; Norton W Milgram; Bruce A Muggenburg; Elizabeth Head
Nutritional management of brain aging in dogs.
Journal of the American Veterinary Medical Association 2005;227(5):722-8.
2005: Anne Taylor; Mathew Blurton-Jones; Seog Woo Rhee; David H Cribbs; Carl W Cotman; Noo Li Jeon
A microfluidic culture platform for CNS axonal injury, regeneration and transport.
Nature methods 2005;2(8):599-605.
2005: Jodie Newman; Robert A Rissman; Floyd Sarsoza; Ronald C Kim; Malcolm Dick; David A Bennett; Carl W Cotman; Troy T Rohn; Elizabeth Head
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Acta neuropathologica 2005;110(2):135-44.
2005: Carl W Cotman
The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo.
Neurochemical research 2005;30(6-7):877-81.
2005: Elizabeth Head; K Moffat; Pritam Das; Floyd Sarsoza; Wayne W Poon; G Landsberg; Carl W Cotman; Michael Murphy
Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats.
Neurobiology of aging 2005;26(5):749-63.
2005: Paul A Adlard; Victoria M Perreau; Viorela Pop; Carl W Cotman
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(17):4217-21.
2005: Paul A Adlard; Victoria M Perreau; Carl W Cotman
The exercise-induced expression of BDNF within the hippocampus varies across life-span.
Neurobiology of aging 2005;26(4):511-20.
2005: Joseph A Araujo; Carl W Cotman; Elizabeth Head; Christa M Studzinski; Norton W Milgram
Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging.
Age (Dordrecht, Netherlands) 2005;27(1):27-37.
2005: Christina T Siwak; P Dwight Tapp; Elizabeth Head; Steven C Zicker; Heather Murphey; Bruce A Muggenburg; Candace J Ikeda-Douglas; Carl W Cotman; Norton W Milgram
Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(3):461-9.
2005: Lori-Ann Christie; Christa M Studzinski; Joseph Araujo; Cleo S K Leung; Candace J Ikeda-Douglas; Elizabeth Head; Carl W Cotman; Norton W Milgram
A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(3):361-9.
2005: Carl W Cotman; Wayne W Poon; Robert A Rissman; Mathew Blurton-Jones
The role of caspase cleavage of tau in Alzheimer disease neuropathology.
Journal of neuropathology and experimental neurology 2005;64(2):104-12.
2005: Nicole C Berchtold; G Chinn; M Chou; J Patrick Kesslak; Carl W Cotman
Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus.
Neuroscience 2005;133(3):853-61.
2005: Victoria M Perreau; Paul A Adlard; Aileen J Anderson; Carl W Cotman
Exercise-induced gene expression changes in the rat spinal cord.
Gene expression 2005;12(2):107-21.
2005: Christie Engesser-Cesar; Aileen J Anderson; D Michele Basso; V Reggie Edgerton; Carl W Cotman
Voluntary wheel running improves recovery from a moderate spinal cord injury.
Journal of neurotrauma 2005;22(1):157-71.
2005: Seog Woo Rhee; Anne Taylor; Christina H Tu; David H Cribbs; Carl W Cotman; Noo Li Jeon
Patterned cell culture inside microfluidic devices.
Lab on a chip 2005;5(1):102-7.
2005: Norton W Milgram; Elizabeth Head; Steven C Zicker; Candace J Ikeda-Douglas; Heather Murphey; Bruce A Muggenburg; Christina T Siwak; D Tapp; Carl W Cotman
Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study.
Neurobiology of aging 2005;26(1):77-90.
2004: Aileen J Anderson; Stephanie Robert; Wencheng Huang; Wise Young; Carl W Cotman
Activation of complement pathways after contusion-induced spinal cord injury.
Journal of neurotrauma 2004;21(12):1831-46.
2004: Jiankang Liu; Elizabeth Head; Hirohiko Kuratsune; Carl W Cotman; Bruce N Ames
Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats.
Annals of the New York Academy of Sciences 2004;1033():117-31.
2004: P Dwight Tapp; Christina T Siwak; Fu Qiang Gao; Jr-Yuan Chiou; Sandra Black; Elizabeth Head; Bruce A Muggenburg; Carl W Cotman; Norton W Milgram; Min-Ying Su
Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(38):8205-13.
2004: Janette Glaser; Rafael Gonzalez; Victoria M Perreau; Carl W Cotman; Hans S Keirstead
Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury.
Journal of neuroscience research 2004;77(5):701-8.
2004: P Dwight Tapp; Christina T Siwak; Elizabeth Head; Carl W Cotman; Heather Murphey; Bruce A Muggenburg; Candace J Ikeda-Douglas; Norton W Milgram
Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks.
Behavioural brain research 2004;153(1):199-210.
2004: Liqi Tong; Robert Balazs; Phillip L Thornton; Carl W Cotman
Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(30):6799-809.
2004: Robert A Rissman; Wayne W Poon; Mathew Blurton-Jones; Salvatore Oddo; Reidun Torp; Michael P. Vitek; Frank M LaFerla; Troy T Rohn; Carl W Cotman
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation 2004;114(1):121-30.
2004: Paul A Adlard; Victoria M Perreau; Christie Engesser-Cesar; Carl W Cotman
The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise.
Neuroscience letters 2004;363(1):43-8.
2004: Norton W Milgram; Elizabeth Head; Steven C Zicker; Candace J Ikeda-Douglas; Heather Murphey; Bruce A Muggenberg; Christina T Siwak; P Dwight Tapp; Stephen R Lowry; Carl W Cotman
Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs.
Experimental gerontology 2004;39(5):753-65.
2004: Julene K Johnson; Brent A Vogt; Ronald Kim; Carl W Cotman; Elizabeth Head
Isolated executive impairment and associated frontal neuropathology.
Dementia and geriatric cognitive disorders 2004;17(4):360-7.
2004: Paul A Adlard; Carl W Cotman
Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression.
Neuroscience 2004;124(4):985-92.
2004: GT Whitman; Carl W Cotman
Oligodendrocyte degeneration in AD.
Neurobiology of aging 2004;25(1):33-6.
2003: Richard J Haier; Michael T Alkire; Nathan White; M R Uncapher; Elizabeth Head; Ira T Lott; Carl W Cotman
Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia.
Neurology 2003;61(12):1673-9.
2003: Ming Zhao; Joseph Su; Elizabeth Head; Carl W Cotman
Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease.
Neurobiology of disease 2003;14(3):391-403.
2003: Pria M D Nippak; Alan D F Chan; Zachariah Campbell; Bruce A Muggenburg; Elizabeth Head; Candace J Ikeda-Douglas; Heather Murphey; Carl W Cotman; Norton W Milgram
Response latency in Canis familiaris: mental ability or mental strategy?
Behavioral neuroscience 2003;117(5):1066-75.
2003: Xiaoning Bi; Elizabeth Head; Carl W Cotman; Gary Lynch
Spatial patterns of mammalian brain aging: distribution of cathepsin D-immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease.
The Journal of comparative neurology 2003;464(3):371-81.
2003: Elizabeth Head; Ira T Lott; Patrick R Hof; Constantin Bouras; Joseph H Su; R Kim; Richard J Haier; Carl W Cotman
Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome.
Journal of neuropathology and experimental neurology 2003;62(9):917-26.
2003: Christina T Siwak; P Dwight Tapp; Steven C Zicker; Heather Murphey; Bruce A Muggenburg; Elizabeth Head; Carl W Cotman; Norton W Milgram
Locomotor activity rhythms in dogs vary with age and cognitive status.
Behavioral neuroscience 2003;117(4):813-24.
2003: Martin Ramsden; Nicole C Berchtold; J Patrick Kesslak; Carl W Cotman; Christian J Pike
Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion.
Brain research 2003;971(2):239-44.
2003: Rakez Kayed; Elizabeth Head; Jennifer L Thompson; Theresa M McIntire; Saskia Milton; Carl W Cotman; Charles G Glabe
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Science (New York, N.Y.) 2003;300(5618):486-9.
2003: Joseph H Su; Aileen J Anderson; David H Cribbs; Christina Tu; Liqi Tong; Patrick Kesslack; Carl W Cotman
Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death.
Neurobiology of disease 2003;12(3):182-93.
2003: David H Cribbs; Anahit Ghochikyan; Vitaly Vasilevko; Mike Tran; Irina Petrushina; Nadya Sadzikava; Davit Babikyan; Patrick Kesslak; Thomas Kieber-Emmons; Carl W Cotman; Michael G Agadjanyan
Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid.
International immunology 2003;15(4):505-14.
2003: Ming Zhao; David H Cribbs; Aileen J Anderson; Brian John Cummings; Joseph H Su; Andrea J Wasserman; Carl W Cotman
The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain.
Neurochemical research 2003;28(2):307-18.
2003: Reidun Torp; Ole Petter Ottersen; Carl W Cotman; Elizabeth Head
Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for beta-amyloid precursor protein processing.
Neuroscience 2003;120(2):291-300.
2003: Celithelma Garcia; Michael J Chen; A A Garza; Carl W Cotman; Amelia A Russo-Neustadt
The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity.
Neuroscience 2003;119(3):721-32.
2003: P Dwight Tapp; Christina T Siwak; Jimena Estrada; Elizabeth Head; Bruce A Muggenburg; Carl W Cotman; Norton W Milgram
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging.
Learning & memory (Cold Spring Harbor, N.Y.) 2003;10(1):64-73.
2002: Troy T Rohn; Robert A Rissman; Michael C Davis; Young Eun Kim; Carl W Cotman; Elizabeth Head
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain.
Neurobiology of disease 2002;11(2):341-54.
2002: Gjumrakch Aliev; Dilara Seyidova; Maxwell Neal; Jiong Shi; Bruce Lamb; Sandra L Siedlak; Harry V Vinters; Elizabeth Head; George Perry; Joseph C LaManna; Robert P Friedland; Carl W Cotman
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
Annals of the New York Academy of Sciences 2002;977():45-64.
2002: Norton W Milgram; Elizabeth Head; Bruce A Muggenburg; Daniel Holowachuk; Heather Murphey; Jimena Estrada; Candace J Ikeda-Douglas; Steven C Zicker; Carl W Cotman
Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy.
Neuroscience and biobehavioral reviews 2002;26(6):679-95.
2002: Elizabeth Head; Ira T Lott; David H Cribbs; Carl W Cotman; Troy T Rohn
Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome.
Neuroscience letters 2002;330(1):99-103.
2002: Carl W Cotman; Elizabeth Head; Bruce A Muggenburg; Steven C Zicker; Norton W Milgram
Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction.
Neurobiology of aging 2002;23(5):809-18.
2002: Norton W Milgram; Steven C Zicker; Elizabeth Head; Bruce A Muggenburg; Heather Murphey; Candace J Ikeda-Douglas; Carl W Cotman
Dietary enrichment counteracts age-associated cognitive dysfunction in canines.
Neurobiology of aging 2002;23(5):737-45.
2002: Katherine A Albert; Hugh C Hemmings; Anna I B Adamo; Steven G Potkin; Schahram Akbarian; Curt A Sandman; Carl W Cotman; William E Bunney; Paul Greengard
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Archives of general psychiatry 2002;59(8):705-12.
2002: Elizabeth Head; J Liu; Tory M Hagen; Bruce A Muggenburg; Norton W Milgram; B N Ames; Carl W Cotman
Oxidative damage increases with age in a canine model of human brain aging.
Journal of neurochemistry 2002;82(2):375-81.
2002: Howard Fillit; Robert N Butler; Alan W O'Connell; Marilyn S Albert; James E Birren; Carl W Cotman; William T Greenough; Ernest Paul Gold; Arthur F Kramer; Lewis H Kuller; Thomas T Perls; Barbara G Sahagan; Tim Tully
Achieving and maintaining cognitive vitality with aging.
Mayo Clinic proceedings. Mayo Clinic 2002;77(7):681-96.
2002: Joseph H Su; J Patrick Kesslak; Elizabeth Head; Carl W Cotman
Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.
Acta neuropathologica 2002;104(1):1-6.
2002: Nicole C Berchtold; J Patrick Kesslak; Carl W Cotman
Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum.
Journal of neuroscience research 2002;68(5):511-21.
2002: Carl W Cotman; Nicole C Berchtold
Exercise: a behavioral intervention to enhance brain health and plasticity.
Trends in neurosciences 2002;25(6):295-301.
2002: Alan D F Chan; Pria M D Nippak; Heather Murphey; Candace J Ikeda-Douglas; Bruce A Muggenburg; Elizabeth Head; Carl W Cotman; Norton W Milgram
Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility.
Behavioral neuroscience 2002;116(3):443-54.
2002: Carl W Cotman; Christie Engesser-Cesar
Exercise enhances and protects brain function.
Exercise and sport sciences reviews 2002;30(2):75-9.
2002: Jiankang Liu; Elizabeth Head; Afshin M Gharib; Wenjun Yuan; Russell T Ingersoll; Tory M Hagen; Carl W Cotman; Bruce N Ames
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2356-61.
2002: Karen SantaCruz; C S Tasaki; R C Kim; Carl W Cotman
Brainstem and cortical Lewy bodies in patients presenting clinically with Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2002;4(1):11-7.
2002: Brian A Soreghan; Christian J Pike; Rakez Kayed; Wenquiang Tian; Saskia Milton; Carl W Cotman; Charles G Glabe
The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties.
Neuromolecular medicine 2002;1(1):81-94.
2001: Nicole C Berchtold; J Patrick Kesslak; Christian J Pike; Paul A Adlard; Carl W Cotman
Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus.
The European journal of neuroscience 2001;14(12):1992-2002.
2001: Liqi Tong; H Shen; Victoria M Perreau; Robert Balazs; Carl W Cotman
Effects of exercise on gene-expression profile in the rat hippocampus.
Neurobiology of disease 2001;8(6):1046-56.
2001: Troy T Rohn; Elizabeth Head; W H Nesse; Carl W Cotman; David H Cribbs
Activation of caspase-8 in the Alzheimer's disease brain.
Neurobiology of disease 2001;8(6):1006-16.
2001: Elizabeth Head; W Garzon-Rodriguez; J K Johnson; Ira T Lott; Carl W Cotman; Charles G Glabe
Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome.
Neurobiology of disease 2001;8(5):792-806.
2001: S E Stoltzner; Nicole C Berchtold; Carl W Cotman; Christian J Pike
Estrogen regulates bcl-x expression in rat hippocampus.
Neuroreport 2001;12(13):2797-800.
2001: K E Nichol; R Kim; Carl W Cotman
Bcl-2 family protein behavior in frontotemporal dementia implies vascular involvement.
Neurology 2001;56(11 Suppl 4):S35-40.
2001: Gregory J Brewer; Jose Espinosa; M P McIlhaney; T P Pencek; J P Kesslak; Carl W Cotman; John J Viel; D C McManus
Culture and regeneration of human neurons after brain surgery.
Journal of neuroscience methods 2001;107(1-2):15-23.
2001: Liqi Tong; Phillip L Thornton; Robert Balazs; Carl W Cotman
Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised.
The Journal of biological chemistry 2001;276(20):17301-6.
2001: Joseph H Su; Ming Zhao; Aileen J Anderson; A Srinivasan; Carl W Cotman
Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.
Brain research 2001;898(2):350-7.
2001: Elizabeth Head; BY Azizeh; Ira T Lott; Andrea J Tenner; Carl W Cotman; David H Cribbs
Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome.
Neurobiology of disease 2001;8(2):252-65.
2001: Troy T Rohn; S M Wong; Carl W Cotman; David H Cribbs
15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis.
Neuroreport 2001;12(4):839-43.
2001: J A Martin; D K Craft; Joseph H Su; Ronald C Kim; Carl W Cotman
Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion.
Neurobiology of aging 2001;22(2):195-207.
2001: H Shen; Liqi Tong; Robert Balazs; Carl W Cotman
Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus.
Neuroscience 2001;107(2):219-29.
2001: Troy T Rohn; Elizabeth Head; Joseph H Su; Aileen J Anderson; Ben A Bahr; Carl W Cotman; David H Cribbs
Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease.
The American journal of pathology 2001;158(1):189-98.
2000: M B Dick; S Hsieh; C Dick-Muehlke; D S Davis; Carl W Cotman
The variability of practice hypothesis in motor learning: does it apply to Alzheimer's disease?
Brain and cognition 2000;44(3):470-89.
2000: Reidun Torp; Elizabeth Head; Carl W Cotman
Ultrastructural analyses of beta-amyloid in the aged dog brain: neuronal beta-amyloid is localized to the plasma membrane.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):801-10.
2000: Elizabeth Head; P L Thornton; L Tong; Carl W Cotman
Initiation and propagation of molecular cascades in human brain aging: insight from the canine model to promote successful aging.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):777-86.
2000: H Callahan; Candace J Ikeda-Douglas; Elizabeth Head; Carl W Cotman; Norton W Milgram
Development of a protocol for studying object recognition memory in the dog.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):693-707.
2000: Elizabeth Head; Carl W Cotman; Norton W Milgram
Canine cognition, aging and neuropathology. Introduction.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):671-3.
2000: Troy T Rohn; KJ Ivins; Ben A Bahr; Carl W Cotman; David H Cribbs
A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis.
Journal of neurochemistry 2000;74(6):2331-42.
2000: J Ulas; T Satou; KJ Ivins; J Patrick Kesslak; Carl W Cotman; R Balázs
Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures.
Glia 2000;30(4):352-61.
2000: David H Cribbs; BY Azizeh; Carl W Cotman; Frank M LaFerla
Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide.
Biochemistry 2000;39(20):5988-94.
2000: T S Kim; Minha Park; RR Nepomuceno; Gail Palmarini; Sara T Winokur; Carl W Cotman; Ulla Bengtsson; Andrea J Tenner
Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P).
Molecular immunology 2000;37(7):377-89.
2000: BY Azizeh; Elizabeth Head; M A Ibrahim; Reidun Torp; Andrea J Tenner; Ronald C Kim; Ira T Lott; Carl W Cotman
Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs.
Experimental neurology 2000;163(1):111-22.
2000: Joseph H Su; K E Nichol; T Sitch; Phillip Sheu; Charles Chubb; Bruce L Miller; K J Tomaselli; Ronald C Kim; Carl W Cotman
DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia.
Experimental neurology 2000;163(1):9-19.
2000: Ruth Mulnard; Carl W Cotman; Claudia H Kawas; Christopher H van Dyck; Mary Sano; Rachelle S Doody; Elizabeth Koss; Eric Pfeiffer; Shelia Jin; A Gamst; Michael Grundman; R Thomas; Leon J Thal
Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study.
JAMA : the journal of the American Medical Association 2000;283(8):1007-15.
2000: B Adams; A Chan; H Callahan; Christina T Siwak; D Tapp; Candace J Ikeda-Douglas; P Atkinson; Elizabeth Head; Carl W Cotman; Norton W Milgram
Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog.
Behavioural brain research 2000;108(1):47-56.
2000: Carl W Cotman; A J Anderson
The brain's microenvironment, early functional loss, and the conversion to Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;924():112-6.
2000: AA Russo-Neustadt; R C Beard; Y M Huang; Carl W Cotman
Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus.
Neuroscience 2000;101(2):305-12.
2000: Elizabeth Head; R McCleary; Fletcher Hahn; Norton W Milgram; Carl W Cotman
Region-specific age at onset of beta-amyloid in dogs.
Neurobiology of aging 2000;21(1):89-96.
2000: Reidun Torp; Elizabeth Head; N W Milgram; F Hahn; Ole Petter Ottersen; Carl W Cotman
Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains.
Neuroscience 2000;96(3):495-506.
1999: AA Russo-Neustadt; R C Beard; Carl W Cotman
Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(5):679-82.
1999: KJ Ivins; Phillip L Thornton; Troy T Rohn; Carl W Cotman
Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.
Neurobiology of disease 1999;6(5):440-9.
1999: J K Johnson; Elizabeth Head; R Kim; Arnold Starr; Carl W Cotman
Clinical and pathological evidence for a frontal variant of Alzheimer disease.
Archives of neurology 1999;56(10):1233-9.
1999: J Davis; David H Cribbs; Carl W Cotman; William E Van Nostrand
Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(3):157-64.
1999: G Deng; Joseph H Su; KJ Ivins; Bennett Van Houten; Carl W Cotman
Bcl-2 facilitates recovery from DNA damage after oxidative stress.
Experimental neurology 1999;159(1):309-18.
1999: D Kim; J Su; Carl W Cotman
Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment.
Brain research 1999;839(2):253-62.
1999: Nicole C Berchtold; Heather S Oliff; PJ Isackson; Carl W Cotman
Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript.
Brain research. Molecular brain research 1999;71(1):11-22.
1999: Maria I Fonseca; Elizabeth Head; Peter Velazquez; Carl W Cotman; Andrea J Tenner
The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age.
Experimental neurology 1999;157(2):277-88.
1999: Malcolm Leissring; B A Paul; Ian Parker; Carl W Cotman; Frank M LaFerla
Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes.
Journal of neurochemistry 1999;72(3):1061-8.
1999: KJ Ivins; J K Ivins; J P Sharp; Carl W Cotman
Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid.
The Journal of biological chemistry 1999;274(4):2107-12.
1999: Norton W Milgram; B Adams; H Callahan; Elizabeth Head; B Mackay; C Thirlwell; Carl W Cotman
Landmark discrimination learning in the dog.
Learning & memory (Cold Spring Harbor, N.Y.) 1999;6(1):54-61.
1998: J K Johnson; Carl W Cotman; C S Tasaki; Gordon L Shaw
Enhancement of spatial-temporal reasoning after a Mozart listening condition in Alzheimer's disease: a case study.
Neurological research 1998;20(8):666-72.
1998: KJ Ivins; E T Bui; Carl W Cotman
Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis.
Neurobiology of disease 1998;5(5):365-78.
1998: Joseph H Su; Brian John Cummings; Carl W Cotman
Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites.
Acta neuropathologica 1998;96(5):463-71.
1998: AA Russo-Neustadt; T J Zomorodian; Carl W Cotman
Preserved cerebellar tyrosine hydroxylase-immunoreactive neuronal fibers in a behaviorally aggressive subgroup of Alzheimer's disease patients.
Neuroscience 1998;87(1):55-61.
1998: Heather S Oliff; Nicole C Berchtold; PJ Isackson; Carl W Cotman
Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus.
Brain research. Molecular brain research 1998;61(1-2):147-53.
1998: Reidun Torp; J H Su; G Deng; Carl W Cotman
GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro.
Neurobiology of disease 1998;5(4):245-52.
1998: Bruce L Miller; Jeffrey L Cummings; Fred Mishkin; KB Boone; F Prince; M Ponton; Carl W Cotman
Emergence of artistic talent in frontotemporal dementia.
Neurology 1998;51(4):978-82.
1998: Min-Ying Su; Elizabeth Head; W M Brooks; Z Wang; Bruce A Muggenburg; G E Adam; R Sutherland; Carl W Cotman; O Nalcioglu
Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging.
Neurobiology of aging 1998;19(5):479-85.
1998: Elizabeth Head; H Callahan; Bruce A Muggenburg; Carl W Cotman; Norton W Milgram
Visual-discrimination learning ability and beta-amyloid accumulation in the dog.
Neurobiology of aging 1998;19(5):415-25.
1998: Anne Eckert; Carl W Cotman; R Zerfass; Michael Hennerici; Walter E Müller
Enhanced vulnerability to apoptotic cell death in sporadic Alzheimer's disease.
Neuroreport 1998;9(11):2443-6.
1998: J Patrick Kesslak; V So; J Choi; Carl W Cotman; Fernando Gomez-Pinilla
Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance?
Behavioral neuroscience 1998;112(4):1012-9.
1998: David A Stenger; J J Hickman; K E Bateman; M S Ravenscroft; Wu Ma; Joseph Pancrazio; Kara M Shaffer; A E Schaffner; David H Cribbs; Carl W Cotman
Microlithographic determination of axonal/dendritic polarity in cultured hippocampal neurons.
Journal of neuroscience methods 1998;82(2):167-73.
1998: Carl W Cotman; N P Hailer; K K Pfister; I Soltesz; M Schachner
Cell adhesion molecules in neural plasticity and pathology: similar mechanisms, distinct organizations?
Progress in neurobiology 1998;55(6):659-69.
1998: Michael P Sheetz; K K Pfister; J Chloë Bulinski; Carl W Cotman
Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration.
Progress in neurobiology 1998;55(6):577-94.
1998: J K Johnson; R McCleary; M H Oshita; Carl W Cotman
Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles.
Brain research 1998;798(1-2):18-24.
1998: BY Azizeh; David H Cribbs; V M Kreng; Carl W Cotman
Cross-linking of NCAM receptors on neurons induces programmed cell death.
Brain research 1998;796(1-2):20-6.
1998: R Balázs; S Miller; Y Chun; J O'Toole; Carl W Cotman
Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture.
Journal of neurochemistry 1998;70(6):2446-58.
1998: R Balázs; S Miller; Y Chun; Carl W Cotman
Receptor-coupled phospholipase C and adenylyl cyclase function with different calcium pools in astrocytes.
Neuroreport 1998;9(7):1397-401.
1998: Nicole C Berchtold; Carl W Cotman
Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s.
Neurobiology of aging 1998;19(3):173-89.
1998: M A Ibrahim; J F Emerson; Carl W Cotman
Magnetic resonance imaging relaxation times and gadolinium-DTPA relaxivity values in human cerebrospinal fluid.
Investigative radiology 1998;33(3):153-62.
1998: Anne Eckert; Carl W Cotman; R Zerfass; Michael Hennerici; Walter E Müller
Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered.
Journal of neural transmission. Supplementum 1998;54():259-67.
1998: Carl W Cotman
Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease.
Neurobiology of aging 1998;19(1 Suppl):S29-32.
1997: Joseph H Su; G Deng; Carl W Cotman
Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
Brain research 1997;774(1-2):193-9.
1997: T Satou; Brian John Cummings; Elizabeth Head; K A Nielson; Fletcher Hahn; Norton W Milgram; Peter Velazquez; David H Cribbs; Andrea J Tenner; Carl W Cotman
The progression of beta-amyloid deposition in the frontal cortex of the aged canine.
Brain research 1997;774(1-2):35-43.
1997: Elizabeth Head; H Callahan; Brian John Cummings; Carl W Cotman; WW Ruehl; B A Muggenberg; Norton W Milgram
Open field activity and human interaction as a function of age and breed in dogs.
Physiology & behavior 1997;62(5):963-71.
1997: Christian J Pike; N Ramezan-Arab; Carl W Cotman
Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants.
Journal of neurochemistry 1997;69(4):1601-11.
1997: Rui J P de Figueiredo; R Oten; J Su; Carl W Cotman
Amyloid deposition in cerebrovascular angiopathy.
Annals of the New York Academy of Sciences 1997;826():463-71.
1997: D E Major; J P Kesslak; Carl W Cotman; Caleb E Finch; Jonathan R Day
Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA.
Neurobiology of aging 1997;18(5):523-6.
1997: J Ulas; Carl W Cotman
Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain.
Neuroscience 1997;79(4):973-82.
1997: AA Russo-Neustadt; Carl W Cotman
Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5573-80.
1997: FM Donovan; Christian J Pike; Carl W Cotman; Dennis D Cunningham
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5316-26.
1997: R Balázs; S Miller; Carmelo Romano; A de Vries; Y Chun; Carl W Cotman
Metabotropic glutamate receptor mGluR5 in astrocytes: pharmacological properties and agonist regulation.
Journal of neurochemistry 1997;69(1):151-63.
1997: Carl W Cotman
The beta-amyloid peptide, peptide self-assembly, and the emergence of biological activities. A new principle in peptide function and the induction of neuropathology.
Annals of the New York Academy of Sciences 1997;814():1-16.
1997: Mary Sano; C Ernesto; Ronald Thomas; M R Klauber; Kimberly Schafer; Michael Grundman; P Woodbury; John H Growdon; Carl W Cotman; Eric Pfeiffer; Lon S Schneider; Leon J Thal
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
The New England journal of medicine 1997;336(17):1216-22.
1997: David H Cribbs; Christian J Pike; S L Weinstein; Peter Velazquez; Carl W Cotman
All-D-enantiomers of beta-amyloid exhibit similar biological properties to all-L-beta-amyloids.
The Journal of biological chemistry 1997;272(11):7431-6.
1997: Joseph H Su; G Deng; Carl W Cotman
Transneuronal degeneration in the spread of Alzheimer's disease pathology: immunohistochemical evidence for the transmission of tau hyperphosphorylation.
Neurobiology of disease 1997;4(5):365-75.
1997: Joseph H Su; G Deng; Carl W Cotman
Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology.
Journal of neuropathology and experimental neurology 1997;56(1):86-93.
1997: Fernando Gomez-Pinilla; S Miller; J Choi; Carl W Cotman
Heparan sulfate potentiates the autocrine action of basic fibroblast growth factor in astrocytes: an in vivo and in vitro study.
Neuroscience 1997;76(1):137-45.
1996: K A Nielson; Brian John Cummings; Carl W Cotman
Constructional apraxia in Alzheimer's disease correlates with neuritic neuropathology in occipital cortex.
Brain research 1996;741(1-2):284-93.
1996: Joseph H Su; Brian John Cummings; Carl W Cotman
Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments.
Brain research 1996;739(1-2):79-87.
1996: G Deng; Christian J Pike; Carl W Cotman
Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells.
FEBS letters 1996;397(1):50-4.
1996: Brian John Cummings; Christian J Pike; R Shankle; Carl W Cotman
Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease.
Neurobiology of aging 1996;17(6):921-33.
1996: David H Cribbs; V M Kreng; A J Anderson; Carl W Cotman
Cross-linking of concanavalin A receptors on cortical neurons induces programmed cell death.
Neuroscience 1996;75(1):173-85.
1996: Carl W Cotman; Joseph H Su
Mechanisms of neuronal death in Alzheimer's disease.
Brain pathology (Zurich, Switzerland) 1996;6(4):493-506.
1996: Christian J Pike; R Balázs; Carl W Cotman
Attenuation of beta-amyloid neurotoxicity in vitro by potassium-induced depolarization.
Journal of neurochemistry 1996;67(4):1774-7.
1996: S Miller; N Sehati; Carmelo Romano; Carl W Cotman
Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5.
Journal of neurochemistry 1996;67(4):1435-47.
1996: G Deng; Joseph H Su; Carl W Cotman
Gene expression of Alzheimer-associated presenilin-2 in the frontal cortex of Alzheimer and aged control brain.
FEBS letters 1996;394(1):17-20.
1996: Carl W Cotman; Andrea J Tenner; Brian John Cummings
beta-Amyloid converts an acute phase injury response to chronic injury responses.
Neurobiology of aging 1996;17(5):723-31.
1996: K A Nielson; J H Nolan; Nicole C Berchtold; C A Sandman; R A Mulnard; Carl W Cotman
Apolipoprotein-E genotyping of diabetic dementia patients: is diabetes rare in Alzheimer's disease?
Journal of the American Geriatrics Society 1996;44(8):897-904.
1996: J Ułas; Carl W Cotman
Dopaminergic denervation of striatum results in elevated expression of NR2A subunit.
Neuroreport 1996;7(11):1789-93.
1996: David H Cribbs; L S Chen; Carl W Cotman; Frank M LaFerla
Injury induces presenilin-1 gene expression in mouse brain.
Neuroreport 1996;7(11):1773-6.
1996: S A Neeper; Fernando Gomez-Pinilla; J Choi; Carl W Cotman
Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain.
Brain research 1996;726(1-2):49-56.
1996: Brian John Cummings; T Satou; Elizabeth Head; Norton W Milgram; Gregory M. Cole; Mary J Savage; M B Podlisny; Dennis J Selkoe; R Siman; Benjamin D Greenberg; Carl W Cotman
Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs.
Neurobiology of aging 1996;17(4):653-9.
1996: Brian John Cummings; Elizabeth Head; A J Afagh; Norton W Milgram; Carl W Cotman
Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine.
Neurobiology of learning and memory 1996;66(1):11-23.
1996: Christian J Pike; N Ramezan-Arab; S Miller; Carl W Cotman
beta-Amyloid increases enzyme activity and protein levels of glutamine synthetase in cultured astrocytes.
Experimental neurology 1996;139(1):167-71.
1996: Christian J Pike; P J Vaughan; Dennis D Cunningham; Carl W Cotman
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro.
Journal of neurochemistry 1996;66(4):1374-82.
1996: Malcolm B Dick; R W Shankle; R E Beth; C Dick-Muehlke; Carl W Cotman; M L Kean
Acquisition and long-term retention of a gross motor skill in Alzheimer's disease patients under constant and varied practice conditions.
The journals of gerontology. Series B, Psychological sciences and social sciences 1996;51(2):P103-11.
1996: A J Anderson; Joseph H Su; Carl W Cotman
DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(5):1710-9.
1996: Brian John Cummings; Elizabeth Head; WW Ruehl; Norton W Milgram; Carl W Cotman
The canine as an animal model of human aging and dementia.
Neurobiology of aging 1996;17(2):259-68.
1996: A Afagh; Brian John Cummings; David H Cribbs; Carl W Cotman; Andrea J Tenner
Localization and cell association of C1q in Alzheimer's disease brain.
Experimental neurology 1996;138(1):22-32.
1996: Joseph H Su; T Satou; A J Anderson; Carl W Cotman
Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease.
Neuroreport 1996;7(2):437-40.
1995: Brian John Cummings; Carl W Cotman
Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity.
Lancet 1995;346(8989):1524-8.
1995: Malcolm B Dick; K A Nielson; R E Beth; W. Rodman Shankle; Carl W Cotman
Acquisition and long-term retention of a fine motor skill in Alzheimer's disease.
Brain and cognition 1995;29(3):294-306.
1995: A G Woods; David H Cribbs; Edward R Whittemore; Carl W Cotman
Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons.
Brain research 1995;697(1-2):53-62.
1995: T Satou; Brian John Cummings; Carl W Cotman
Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity.
Brain research 1995;697(1-2):35-43.
1995: Christian J Pike; M J Overman; Carl W Cotman
Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro.
The Journal of biological chemistry 1995;270(41):23895-8.
1995: D T Loo; M C Althoen; Carl W Cotman
Differentiation of serum-free mouse embryo cells into astrocytes is accompanied by induction of glutamine synthetase activity.
Journal of neuroscience research 1995;42(2):184-91.
1995: Elizabeth Head; R Mehta; J Hartley; M Kameka; Brian John Cummings; Carl W Cotman; WW Ruehl; Norton W Milgram
Spatial learning and memory as a function of age in the dog.
Behavioral neuroscience 1995;109(5):851-8.
1995: A J Anderson; Christian J Pike; Carl W Cotman
Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.
Journal of neurochemistry 1995;65(4):1487-98.
1995: S Miller; Carmelo Romano; Carl W Cotman
Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(9):6103-9.
1995: Edward R Whittemore; D T Loo; J A Watt; Carl W Cotman
A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture.
Neuroscience 1995;67(4):921-32.
1995: J Davis-Salinas; S M Saporito-Irwin; Carl W Cotman; William E Van Nostrand
Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells.
Journal of neurochemistry 1995;65(2):931-4.
1995: A R Korotzer; J Watt; David H Cribbs; Andrea J Tenner; D Burdick; Charles G Glabe; Carl W Cotman
Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia.
Experimental neurology 1995;134(2):214-21.
1995: B H Choi; R C Kim; P J Vaughan; A Lau; William E Van Nostrand; Carl W Cotman; Dennis D Cunningham
Decreases in protease nexins in Alzheimer's disease brain.
Neurobiology of aging 1995;16(4):557-62.
1995: P J Vaughan; Christian J Pike; Carl W Cotman; Dennis D Cunningham
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 2):5389-401.
1995: R J deFigueiredo; W. Rodman Shankle; A Maccato; Malcolm B Dick; P Mundkur; I Mena; Carl W Cotman
Neural-network-based classification of cognitively normal, demented, Alzheimer disease and vascular dementia from single photon emission with computed tomography image data from brain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5530-4.
1995: Fernando Gomez-Pinilla; E A van der Wal; Carl W Cotman
Possible coordinated gene expressions for FGF receptor, FGF-5, and FGF-2 following seizures.
Experimental neurology 1995;133(2):164-74.
1995: D M Araujo; Carl W Cotman
Differential effects of interleukin-1 beta and interleukin-2 on glia and hippocampal neurons in culture.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1995;13(3-4):201-12.
1995: S Miller; J Patrick Kesslak; Carmelo Romano; Carl W Cotman
Roles of metabotropic glutamate receptors in brain plasticity and pathology.
Annals of the New York Academy of Sciences 1995;757():460-74.
1995: Christian J Pike; Brian John Cummings; Carl W Cotman
Early association of reactive astrocytes with senile plaques in Alzheimer's disease.
Experimental neurology 1995;132(2):172-9.
1995: J Patrick Kesslak; D Yuan; S Neeper; Carl W Cotman
Vulnerability of the hippocampus to kainate excitotoxicity in the aged, mature and young adult rat.
Neuroscience letters 1995;188(2):117-20.
1995: Fernando Gomez-Pinilla; Loan Vu; Carl W Cotman
Regulation of astrocyte proliferation by FGF-2 and heparan sulfate in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 1):2021-9.
1995: R J Defigueiredo; Brian John Cummings; P Y Mundkur; Carl W Cotman
Color image analysis in neuroanatomical research: application to senile plaque subtype quantification in Alzheimer's disease.
Neurobiology of aging 1995;16(2):211-23.
1995: Christian J Pike; Carl W Cotman
Calretinin-immunoreactive neurons are resistant to beta-amyloid toxicity in vitro.
Brain research 1995;671(2):293-8.
1995: Carl W Cotman; A J Anderson
A potential role for apoptosis in neurodegeneration and Alzheimer's disease.
Molecular neurobiology 1995;10(1):19-45.
1995: A R Korotzer; Edward R Whittemore; Carl W Cotman
Differential regulation by beta-amyloid peptides of intracellular free Ca2+ concentration in cultured rat microglia.
European journal of pharmacology 1995;288(2):125-30.
1995: S A Neeper; Fernando Gomez-Pinilla; J Choi; Carl W Cotman
Exercise and brain neurotrophins.
Nature 1995;373(6510):109.
1995: W. Rodman Shankle; K A Nielson; Carl W Cotman
Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients.
Alzheimer disease and associated disorders 1995;9(4):233-7.
1995: WW Ruehl; David Bruyette; A DePaoli; Carl W Cotman; Elizabeth Head; Norton W Milgram; Brian John Cummings
Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy.
Progress in brain research 1995;106():217-25.
1995: Christian J Pike; A J Walencewicz-Wasserman; J Kosmoski; David H Cribbs; Charles G Glabe; Carl W Cotman
Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity.
Journal of neurochemistry 1995;64(1):253-65.
1994: P J Vaughan; J Su; Carl W Cotman; Dennis D Cunningham
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease.
Brain research 1994;668(1-2):160-70.
1994: J H Su; A J Anderson; Brian John Cummings; Carl W Cotman
Immunohistochemical evidence for apoptosis in Alzheimer's disease.
Neuroreport 1994;5(18):2529-33.
1994: Carl W Cotman; Edward R Whittemore; J A Watt; A J Anderson; D T Loo
Possible role of apoptosis in Alzheimer's disease.
Annals of the New York Academy of Sciences 1994;747():36-49.
1994: J H Su; Brian John Cummings; Carl W Cotman
Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites.
Neuroreport 1994;5(17):2358-62.
1994: J Ułas; F B Weihmuller; L C Brunner; Jeffrey N. Joyce; John F Marshall; Carl W Cotman
Selective increase of NMDA-sensitive glutamate binding in the striatum of Parkinson's disease, Alzheimer's disease, and mixed Parkinson's disease/Alzheimer's disease patients: an autoradiographic study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(11 Pt 1):6317-24.
1994: Christian J Pike; Brian John Cummings; R Monzavi; Carl W Cotman
Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease.
Neuroscience 1994;63(2):517-31.
1994: J A Watt; Christian J Pike; A J Walencewicz-Wasserman; Carl W Cotman
Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons.
Brain research 1994;661(1-2):147-56.
1994: S Miller; Richard J Bridges; A Richard Chamberlin; Carl W Cotman
Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes.
European journal of pharmacology 1994;269(2):235-41.
1994: M D Smyth; David H Cribbs; Andrea J Tenner; W. Rodman Shankle; M Dick; J P Kesslak; Carl W Cotman
Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state.
Neurobiology of aging 1994;15(5):609-14.
1994: D T Loo; M C Althoen; Carl W Cotman
Down regulation of nestin by TGF-beta or serum in SFME cells accompanies differentiation into astrocytes.
Neuroreport 1994;5(13):1585-8.
1994: Fernando Gomez-Pinilla; J W Lee; Carl W Cotman
Distribution of basic fibroblast growth factor in the developing rat brain.
Neuroscience 1994;61(4):911-23.
1994: Edward R Whittemore; D T Loo; Carl W Cotman
Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons.
Neuroreport 1994;5(12):1485-8.
1994: Richard J Bridges; F E Lovering; H Koch; Carl W Cotman; A Richard Chamberlin
A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate.
Neuroscience letters 1994;174(2):193-7.
1994: H Jiang; D Burdick; Charles G Glabe; Carl W Cotman; Andrea J Tenner
beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(10):5050-9.
1994: E A Van Der Wal; Fernando Gomez-Pinilla; Carl W Cotman
Seizure-associated induction of basic fibroblast growth factor and its receptor in the rat brain.
Neuroscience 1994;60(2):311-23.
1994: M D Smyth; J P Kesslak; Brian John Cummings; Carl W Cotman
Analysis of brain injury following intrahippocampal administration of beta-amyloid in streptozotocin-treated rats.
Neurobiology of aging 1994;15(2):153-9.
1994: J H Su; Brian John Cummings; Carl W Cotman
Subpopulations of dystrophic neurites [correction of neuritis] in Alzheimer's brain with distinct immunocytochemical and argentophilic characteristics.
Brain research 1994;637(1-2):37-44.
1994: A J Anderson; Brian John Cummings; Carl W Cotman
Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology.
Experimental neurology 1994;125(2):286-95.
1994: John H Weiss; Christian J Pike; Carl W Cotman
Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.
Journal of neurochemistry 1994;62(1):372-5.
1994: Carl W Cotman
Report of Alzheimer's disease Working Group A.
Neurobiology of aging 1994;15 Suppl 2():S17-22.
1993: David A Stenger; Christian J Pike; J J Hickman; Carl W Cotman
Surface determinants of neuronal survival and growth on self-assembled monolayers in culture.
Brain research 1993;630(1-2):136-47.
1993: Brian John Cummings; J H Su; Carl W Cotman
Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease.
Experimental neurology 1993;124(2):315-25.
1993: J S Kahle; Carl W Cotman
Synaptic reorganization in the hippocampus: an electrophysiological analysis.
Annals of the New York Academy of Sciences 1993;702():61-74.
1993: Brian John Cummings; Joseph H Su; Carl W Cotman; R White; M J Russell
Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease.
Neurobiology of aging 1993;14(6):547-60.
1993: S L Wagner; William E Van Nostrand; A L Lau; J S Farrow; M Suzuki; raymond bartus; R Schuppek; A Nguyen; Carl W Cotman; Dennis D Cunningham
Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates.
Brain research 1993;626(1-2):90-8.
1993: J H Su; Brian John Cummings; Carl W Cotman
Identification and distribution of axonal dystrophic neurites in Alzheimer's disease.
Brain research 1993;625(2):228-37.
1993: A R Korotzer; Christian J Pike; Carl W Cotman
beta-Amyloid peptides induce degeneration of cultured rat microglia.
Brain research 1993;624(1-2):121-5.
1993: Lisa F Berkman; Teresa Seeman; Marilyn S Albert; D Blazer; R Kahn; Richard C Mohs; Caleb E Finch; E Schneider; Carl W Cotman; G McClearn
High, usual and impaired functioning in community-dwelling older men and women: findings from the MacArthur Foundation Research Network on Successful Aging.
Journal of clinical epidemiology 1993;46(10):1129-40.
1993: Edward R Whittemore; A R Korotzer; A Etebari; Carl W Cotman
Carbachol increases intracellular free calcium in cultured rat microglia.
Brain research 1993;621(1):59-64.
1993: D T Loo; Agata Copani; Christian J Pike; Edward R Whittemore; A J Walencewicz; Carl W Cotman
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):7951-5.
1993: Christian J Pike; Carl W Cotman
Cultured GABA-immunoreactive neurons are resistant to toxicity induced by beta-amyloid.
Neuroscience 1993;56(2):269-74.
1993: J Ułas; L Nguyen; Carl W Cotman
Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex.
Neuroreport 1993;4(8):1049-51.
1993: S Miller; Richard J Bridges; Carl W Cotman
Stimulation of phosphoinositide hydrolysis by trans-(+/-)-ACPD is greatly enhanced when astrocytes are cultured in a serum-free defined medium.
Brain research 1993;618(1):175-8.
1993: J S Kahle; Carl W Cotman
L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices.
The Journal of pharmacology and experimental therapeutics 1993;266(1):207-15.
1993: Kathy R Magnusson; Carl W Cotman
Age-related changes in excitatory amino acid receptors in two mouse strains.
Neurobiology of aging 1993;14(3):197-206.
1993: J S Kahle; J Ułas; Carl W Cotman
Increased sensitivity to adenosine in the rat dentate gyrus molecular layer two weeks after partial entorhinal lesions.
Brain research 1993;609(1-2):201-10.
1993: Christian J Pike; D Burdick; A J Walencewicz; Charles G Glabe; Carl W Cotman
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(4):1676-87.
1993: V K Vijayan; Shan Shan Zhou; M J Russell; James W Geddes; William G Ellis; Carl W Cotman
Perineuronal satellitosis in the human hippocampal formation.
Hippocampus 1993;3(2):239-50.
1993: Fernando Gomez-Pinilla; Carl W Cotman
Distribution of fibroblast growth factor 5 mRNA in the rat brain: an in situ hybridization study.
Brain research 1993;606(1):79-86.
1993: M J Russell; Brian John Cummings; B F Profitt; Charles J Wysocki; A N Gilbert; Carl W Cotman
Life span changes in the verbal categorization of odors.
Journal of gerontology 1993;48(2):P49-53.
1993: Kathy R Magnusson; Carl W Cotman
Effects of aging on NMDA and MK801 binding sites in mice.
Brain research 1993;604(1-2):334-7.
1993: J Ułas; L C Brunner; L Nguyen; Carl W Cotman
Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: a quantitative autoradiographic study.
Neuroscience 1993;52(4):843-54.
1993: D M Araujo; Carl W Cotman
Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors.
Brain research 1993;600(1):49-55.
1993: E A van der Wal; Fernando Gomez-Pinilla; Carl W Cotman
Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies.
Neuroreport 1993;4(1):69-72.
1993: J H Neal; Carl W Cotman
Human brain tumor cyst fluid is mitogenic for primary astrocytes in culture.
Neurosurgery 1993;32(1):95-8; discussion 98-9.
1993: Carl W Cotman; Christian J Pike; Brian John Cummings
Adaptive versus pathological plasticity. Possible contributions to age-related dementia.
Advances in neurology 1993;59():35-45.
1993: J S Kahle; Carl W Cotman
Adenosine, L-AP4, and baclofen modulation of paired-pulse potentiation in the dentate gyrus: interstimulus interval-dependent pharmacology.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;94(1):97-104.
1993: J Ułas; Carl W Cotman
Excitatory amino acid receptors in schizophrenia.
Schizophrenia bulletin 1993;19(1):105-17.
1992: Joseph H Su; Brian John Cummings; Carl W Cotman
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease.
Neuroscience 1992;51(4):801-13.
1992: A Kammesheidt; F M Boyce; A F Spanoyannis; Brian John Cummings; M Ortegón; Carl W Cotman; J L Vaught; Rachael L Neve
Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10857-61.
1992: F B Weihmuller; J Ulas; L Nguyen; Carl W Cotman; John F Marshall
Elevated NMDA receptors in parkinsonian striatum.
Neuroreport 1992;3(11):977-80.
1992: Brian John Cummings; G J Yee; Carl W Cotman
bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy.
Brain research 1992;591(2):271-6.
1992: Carl W Cotman; Christian J Pike; Agata Copani
beta-Amyloid neurotoxicity: a discussion of in vitro findings.
Neurobiology of aging 1992;13(5):587-90.
1992: Richard J Bridges; CG Hatalski; S N Shim; Brian John Cummings; V Vijayan; A Kundi; Carl W Cotman
Gliotoxic actions of excitatory amino acids.
Neuropharmacology 1992;31(9):899-907.
1992: Christian J Pike; Brian John Cummings; Carl W Cotman
beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology.
Neuroreport 1992;3(9):769-72.
1992: James W Geddes; J Ułas; L C Brunner; wonsick choe; Carl W Cotman
Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: non-N-methyl-D-aspartate receptors.
Neuroscience 1992;50(1):23-34.
1992: J Y Koh; Carl W Cotman
Programmed cell death: its possible contribution to neurotoxicity mediated by calcium channel antagonists.
Brain research 1992;587(2):233-40.
1992: Fernando Gomez-Pinilla; Carl W Cotman
Transient lesion-induced increase of basic fibroblast growth factor and its receptor in layer VIb (subplate cells) of the adult rat cerebral cortex.
Neuroscience 1992;49(4):771-80.
1992: A S Clark; Carl W Cotman
Adrenal hormone effects on hippocampal excitatory amino acid binding.
Brain research 1992;585(1-2):161-8.
1992: J Ułas; L C Brunner; James W Geddes; wonsick choe; Carl W Cotman
N-methyl-D-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease.
Neuroscience 1992;49(1):45-61.
1992: Brian John Cummings; Joseph H Su; James W Geddes; William E Van Nostrand; S L Wagner; D D Cunningham; Carl W Cotman
Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease.
Neuroscience 1992;48(4):763-77.
1992: D M Araujo; Carl W Cotman
Basic FGF in astroglial, microglial, and neuronal cultures: characterization of binding sites and modulation of release by lymphokines and trophic factors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(5):1668-78.
1992: S Miller; Carl W Cotman; Richard J Bridges
1-Aminocyclopentane-trans-1,3-dicarboxylic acid induces glutamine synthetase activity in cultured astrocytes.
Journal of neurochemistry 1992;58(5):1967-70.
1992: William E Van Nostrand; S L Wagner; W. Rodman Shankle; J S Farrow; M Dick; J M Rozemuller; M A Kuiper; E C Wolters; J Zimmerman; Carl W Cotman
Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2551-5.
1992: A S Clark; K R Magnusson; Carl W Cotman
In vitro autoradiography of hippocampal excitatory amino acid binding in aged Fischer 344 rats: relationship to performance on the Morris water maze.
Behavioral neuroscience 1992;106(2):324-35.
1992: J S Taube; J Patrick Kesslak; Carl W Cotman
Lesions of the rat postsubiculum impair performance on spatial tasks.
Behavioral and neural biology 1992;57(2):131-43.
1992: D F Emerich; B A Black; J P Kesslak; Carl W Cotman; TJ Walsh
Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A.
Brain research bulletin 1992;28(2):219-26.
1992: James W Geddes; L Brunner; Carl W Cotman; G Buzsáki
Alterations in [3H]kainate and N-methyl-D-aspartate-sensitive L-[3H]-glutamate binding in the rat hippocampal formation following fimbria-fornix lesions.
Experimental neurology 1992;115(2):271-81.
1992: D M Araujo; Carl W Cotman
Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease.
Brain research 1992;569(1):141-5.
1992: D Burdick; B Soreghan; M Kwon; J Kosmoski; Mary Knauer; A Henschen; J Yates; Carl W Cotman; Charles G Glabe
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.
The Journal of biological chemistry 1992;267(1):546-54.
1992: A R Korotzer; Carl W Cotman
Voltage-gated currents expressed by rat microglia in culture.
Glia 1992;6(2):81-8.
1992: Fernando Gomez-Pinilla; J W Lee; Carl W Cotman
Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbria-fornix transection.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(1):345-55.
1992: Carl W Cotman
An overview and perspective on the potential relevance of neuronal growth to the development of epilepsy and epilepsy-related disturbances.
Epilepsy research. Supplement 1992;9():257-61; discussion 261-4.
1991: Agata Copani; J Y Koh; Carl W Cotman
Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation.
Neuroreport 1991;2(12):763-5.
1991: William E Van Nostrand; J S Farrow; S L Wagner; R Bhasin; Dmitry Goldgaber; Carl W Cotman; Dennis D Cunningham
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10302-6.
1991: Christian J Pike; A J Walencewicz; Charles G Glabe; Carl W Cotman
In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity.
Brain research 1991;563(1-2):311-4.
1991: J Y Koh; E Palmer; Carl W Cotman
Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9431-5.
1991: Kevin J Anderson; R J Bridges; Carl W Cotman
Increased density of excitatory amino acid transport sites in the hippocampal formation following an entorhinal lesion.
Brain research 1991;562(2):285-90.
1991: J Y Koh; E Palmer; A Lin; Carl W Cotman
A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture.
Brain research 1991;561(2):338-43.
1991: Monte Buchsbaum; J Patrick Kesslak; G Lynch; H Chui; J Wu; N Sicotte; Erin A Hazlett; E Teng; Carl W Cotman
Temporal and hippocampal metabolic rate during an olfactory memory task assessed by positron emission tomography in patients with dementia of the Alzheimer type and controls. Preliminary studies.
Archives of general psychiatry 1991;48(9):840-7.
1991: D R Stevens; Carl W Cotman
Long-term potentiation of excitatory and slow inhibitory synaptic potentials in the hippocampal-septal projection of the rat.
Brain research 1991;558(1):120-2.
1991: J Patrick Kesslak; A Korotzer; A Song; K Kamali; Carl W Cotman
Effects of tetrahydroaminoacridine (THA) on functional recovery after sequential lesion of the entorhinal cortex.
Brain research 1991;557(1-2):57-63.
1991: Christian J Pike; A J Walencewicz; Charles G Glabe; Carl W Cotman
Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures.
European journal of pharmacology 1991;207(4):367-8.
1991: Edward R Whittemore; Carl W Cotman
Agonists selective for phosphoinositide-coupled receptors sensitize neurons to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4).
Brain research 1991;555(2):215-9.
1991: James W Geddes; Carl W Cotman
Plasticity in Alzheimer's disease: too much or not enough?
Neurobiology of aging 1991;12(4):330-3; discussion 352-5.
1991: V K Vijayan; James W Geddes; K J Anderson; H Chang-Chui; William G Ellis; Carl W Cotman
Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation.
Experimental neurology 1991;112(1):72-8.
1991: R M Sullivan; S Taborsky-Barba; R Mendoza; A Itano; Michael Leon; Carl W Cotman; T F Payne; Ira T Lott
Olfactory classical conditioning in neonates.
Pediatrics 1991;87(4):511-8.
1991: Richard J Bridges; M S Stanley; M W Anderson; Carl W Cotman; A Richard Chamberlin
Conformationally defined neurotransmitter analogues. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer.
Journal of medicinal chemistry 1991;34(2):717-25.
1991: Richard J Bridges; J Y Koh; CG Hatalski; Carl W Cotman
Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione.
European journal of pharmacology 1991;192(1):199-200.
1991: C Peterson; P Vanderklish; Peter Seubert; Carl W Cotman; Gary Lynch
Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors.
Neuroscience letters 1991;121(1-2):239-43.
1991: J Patrick Kesslak; Orhan Nalcioglu; Carl W Cotman
Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease.
Neurology 1991;41(1):51-4.
1991: Carl W Cotman; Fernando Gomez-Pinilla
Basic fibroblast growth factor in the mature brain and its possible role in Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;638():221-31.
1990: J Y Koh; L L Yang; Carl W Cotman
Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage.
Brain research 1990;533(2):315-20.
1990: Fernando Gomez-Pinilla; Brian John Cummings; Carl W Cotman
Induction of basic fibroblast growth factor in Alzheimer's disease pathology.
Neuroreport 1990;1(3-4):211-4.
1990: C Peterson; J F Giguere; Carl W Cotman; R F Butterworth
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Journal of neurochemistry 1990;55(2):386-90.
1990: J Ułas; D T Monaghan; Carl W Cotman
Kainate receptors in the rat hippocampus: a distribution and time course of changes in response to unilateral lesions of the entorhinal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(7):2352-62.
1990: J Borg; P J Kesslak; Carl W Cotman
Peripheral administration of a long-chain fatty alcohol promotes septal cholinergic neurons survival after fimbria-fornix transection.
Brain research 1990;518(1-2):295-8.
1990: James W Geddes; L D Cahan; S M Cooper; R C Kim; B H Choi; Carl W Cotman
Altered distribution of excitatory amino acid receptors in temporal lobe epilepsy.
Experimental neurology 1990;108(3):214-20.
1990: C Peterson; Carl W Cotman
Decreased survival of hippocampal neurons in medium conditioned by fibroblasts from aged and Alzheimer donors.
Brain research 1990;515(1-2):39-44.
1990: M J Russell; V K Vijayan; Robert B Gibbs; James W Geddes; C H Jacobson; Carl W Cotman
Long-term survival of neural transplants to senescence in rats.
Experimental neurology 1990;108(2):105-8.
1990: Michel Baudry; D Monaghan; Carl W Cotman; C A Altar
Regional distribution of alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding sites in rat brain: effect of chemical modification of SH- groups in tissue sections.
Journal of neurochemistry 1990;54(5):1682-8.
1990: J S Whitson; C G Glabe; E Shintani; A Abcar; Carl W Cotman
Beta-amyloid protein promotes neuritic branching in hippocampal cultures.
Neuroscience letters 1990;110(3):319-24.
1990: James W Geddes; J Wong; B H Choi; R C Kim; Carl W Cotman; F D Miller
Increased expression of the embryonic form of a developmentally regulated mRNA in Alzheimer's disease.
Neuroscience letters 1990;109(1-2):54-61.
1990: Peter Seubert; C Peterson; P Vanderklish; Carl W Cotman; Gary Lynch
Increased spectrin proteolysis in the brindled mouse brain.
Neuroscience letters 1990;108(3):303-8.
1990: Carl W Cotman; James W Geddes; J S Kahle
Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms?
Progress in brain research 1990;83():427-34.
1990: J Ułas; D T Monaghan; Carl W Cotman
Plastic response of hippocampal excitatory amino acid receptors to deafferentation and reinnervation.
Neuroscience 1990;34(1):9-17.
1990: E Palmer; K Nangel-Taylor; J D Krause; A Roxas; Carl W Cotman
Changes in excitatory amino acid modulation of phosphoinositide metabolism during development.
Brain research. Developmental brain research 1990;51(1):132-4.
1990: James W Geddes; M C Wilson; F D Miller; Carl W Cotman
Molecular markers of reactive plasticity.
Advances in experimental medicine and biology 1990;268():425-32.
1990: Kevin J Anderson; D T Monaghan; R J Bridges; A L Tavoularis; Carl W Cotman
Autoradiographic characterization of putative excitatory amino acid transport sites.
Neuroscience 1990;38(2):311-22.
1990: Carl W Cotman; James W Geddes; J Ulas; M Klein
Plasticity of excitatory amino acid receptors: implications for aging and Alzheimer's disease.
Progress in brain research 1990;86():55-61.
1990: L D Cahan; James W Geddes; B H Choi; Carl W Cotman
Excitotoxic amino acid receptors in human complex partial epilepsy.
Stereotactic and functional neurosurgery 1990;54-55():21-4.
1990: James W Geddes; Ellen J Hess; R A Hart; J Patrick Kesslak; Carl W Cotman; M C Wilson
Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker.
Neuroscience 1990;38(2):515-25.
1990: J Poirier; Patrick May; H H Osterburg; James W Geddes; Carl W Cotman; Caleb E Finch
Selective alterations of RNA in rat hippocampus after entorhinal cortex lesioning.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):303-7.
1989: S L Wagner; James W Geddes; Carl W Cotman; A L Lau; D Gurwitz; P J Isackson; Dennis D Cunningham
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8284-8.
1989: Carl W Cotman; G S Lynch
The neurobiology of learning and memory.
Cognition 1989;33(1-2):201-41.
1989: William E Van Nostrand; S L Wagner; M Suzuki; B H Choi; J S Farrow; James W Geddes; Carl W Cotman; Dennis D Cunningham
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor.
Nature 1989;341(6242):546-9.
1989: C Peterson; Carl W Cotman
Strain-dependent decrease in glutamate binding to the N-methyl-D-aspartic acid receptor during aging.
Neuroscience letters 1989;104(3):309-13.
1989: James W Geddes; Carl W Cotman
Plasticity, pathology, and Alzheimer's disease.
Neurobiology of aging 1989;10(5):571-3; discussion 588-90.
1989: Carl W Cotman; James W Geddes; Richard J Bridges; D T Monaghan
N-methyl-D-aspartate receptors and Alzheimer's disease.
Neurobiology of aging 1989;10(5):603-5; discussion 618-20.
1989: Gregory J Brewer; Carl W Cotman
Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen.
Brain research 1989;494(1):65-74.
1989: E Palmer; D T Monaghan; Carl W Cotman
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
European journal of pharmacology 1989;166(3):585-7.
1989: Jeffrey N. Joyce; Robert B Gibbs; Carl W Cotman; J F Marshall
Regulation of muscarinic receptors in hippocampus following cholinergic denervation and reinnervation by septal and striatal transplants.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(8):2776-91.
1989: C Peterson; J H Neal; Carl W Cotman
Development of N-methyl-D-aspartate excitotoxicity in cultured hippocampal neurons.
Brain research. Developmental brain research 1989;48(2):187-95.
1989: R Balázs; N Hack; O S Jørgensen; Carl W Cotman
N-methyl-D-aspartate promotes the survival of cerebellar granule cells: pharmacological characterization.
Neuroscience letters 1989;101(3):241-6.
1989: Richard J Bridges; D R Stevens; J S Kahle; P B Nunn; M Kadri; Carl W Cotman
Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that beta-L-ODAP is a selective non-NMDA agonist.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):2073-9.
1989: Gregory J Brewer; Carl W Cotman
NMDA receptor regulation of neuronal morphology in cultured hippocampal neurons.
Neuroscience letters 1989;99(3):268-73.
1989: Fernando Gomez-Pinilla; H Tram; Carl W Cotman; M Nieto-Sampedro
Neuroprotective effect of MK-801 and U-50488H after contusive spinal cord injury.
Experimental neurology 1989;104(2):118-24.
1989: J S Whitson; Dennis J Selkoe; Carl W Cotman
Amyloid beta protein enhances the survival of hippocampal neurons in vitro.
Science (New York, N.Y.) 1989;243(4897):1488-90.
1989: J S Kahle; Carl W Cotman
Carbachol depresses synaptic responses in the medial but not the lateral perforant path.
Brain research 1989;482(1):159-63.
1989: E Westerberg; D T Monaghan; H Kalimo; Carl W Cotman; Tadeusz Wieloch
Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):798-805.
1989: Fernando Gomez-Pinilla; Carl W Cotman; M Nieto-Sampedro
NGF receptor immunoreactivity in aged rat brain.
Brain research 1989;479(2):255-62.
1989: James W Geddes; S M Cooper; Carl W Cotman; S Patel; B S Meldrum
N-methyl-D-aspartate receptors in the cortex and hippocampus of baboon (Papio anubis and Papio papio).
Neuroscience 1989;32(1):39-47.
1989: Carl W Cotman; D Monaghan
Multiple excitatory amino acid receptor regulation of intracellular Ca2+. Implications for aging and Alzheimer's disease.
Annals of the New York Academy of Sciences 1989;568():138-48.
1989: D T Monaghan; Richard J Bridges; Carl W Cotman
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system.
Annual review of pharmacology and toxicology 1989;29():365-402.
1988: D T Monaghan; H J Olverman; L Nguyen; Jeffrey C Watkins; Carl W Cotman
Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9836-40.
1988: E Palmer; D T Monaghan; Carl W Cotman
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Brain research 1988;464(2):161-5.
1988: J Patrick Kesslak; Carl W Cotman; H C Chui; S Van den Noort; H Fang; R Pfeffer; Gary Lynch
Olfactory tests as possible probes for detecting and monitoring Alzheimer's disease.
Neurobiology of aging 1988;9(4):399-403.
1988: J Patrick Kesslak; A Walencewicz; L Calin; M Nieto-Sampedro; Carl W Cotman
Hippocampal but not astrocyte transplants enhance recovery on a forced choice alternation task after kainate lesions.
Brain research 1988;454(1-2):347-54.
1988: R S Lasher; P F Erickson; E E Mena; Carl W Cotman
The binding of a monoclonal antibody reactive with pp60v-src to the rat CNS both in vitro and in vivo: evidence that the epitope is present intracellularly as well as being associated with a number of antigenically related polypeptides located externally in the plasma membrane only in the synaptic region.
Brain research 1988;452(1-2):184-202.
1988: M Nieto-Sampedro; R Lim; D J Hicklin; Carl W Cotman
Early release of glia maturation factor and acidic fibroblast growth factor after rat brain injury.
Neuroscience letters 1988;86(3):361-5.
1988: K J Anderson; Robert B Gibbs; Carl W Cotman
Transmitter phenotype is a major determinant in the specificity of synapses formed by cholinergic neurons transplanted to the hippocampus.
Neuroscience 1988;25(1):19-25.
1988: J Lincoln; Robert Coopersmith; E W Harris; Carl W Cotman; Michael Leon
NMDA receptor activation and early olfactory learning.
Brain research 1988;467(2):309-12.
1988: K J Anderson; D Dam; S Lee; Carl W Cotman
Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo.
Nature 1988;332(6162):360-1.
1988: A I Millaruelo; M Nieto-Sampedro; Carl W Cotman
Cooperation between nerve growth factor and laminin or fibronectin in promoting sensory neuron survival and neurite outgrowth.
Brain research 1988;466(2):219-28.
1988: Richard J Bridges; M M Kadri; D T Monaghan; P B Nunn; Jeffrey C Watkins; Carl W Cotman
Inhibition of [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid.
European journal of pharmacology 1988;145(3):357-9.
1988: Carl W Cotman; K J Anderson
Synaptic plasticity and functional stabilization in the hippocampal formation: possible role in Alzheimer's disease.
Advances in neurology 1988;47():313-35.
1988: Jeffrey N. Joyce; Robert B Gibbs; Carl W Cotman; J F Marshall
Regulation of acetylcholine muscarinic receptors by embryonic septal grafts showing cholinergic innervation of host hippocampus.
Progress in brain research 1988;78():109-16.
1988: Carl W Cotman; J P Kesslak
The role of trophic factors in behavioral recovery and integration of transplants.
Progress in brain research 1988;78():311-9.
1988: Carl W Cotman; D T Monaghan; A H Ganong
Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity.
Annual review of neuroscience 1988;11():61-80.
1987: Fernando Gomez-Pinilla; Carl W Cotman; M Nieto-Sampedro
NGF receptor immunoreactivity in rat brain: topographic distribution and response to entorhinal ablation.
Neuroscience letters 1987;82(3):260-6.
1987: D L Needels; M Nieto-Sampedro; Carl W Cotman
Long-term support by injured brain extract of a subpopulation of ciliary ganglion neurons purified by differential adhesion.
Neurochemical research 1987;12(10):901-7.
1987: Robert B Gibbs; J Yu; Carl W Cotman
Entorhinal transplants and spatial memory abilities in rats.
Behavioural brain research 1987;26(1):29-35.
1987: D R Stevens; Carl W Cotman
Excitatory actions of tetrahydro-9-aminoacridine (THA) on hippocampal pyramidal neurons.
Neuroscience letters 1987;79(3):301-5.
1987: E W Harris; D R Stevens; Carl W Cotman
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Brain research 1987;418(2):361-5.
1987: D E Rosenblatt; Carl W Cotman; M Nieto-Sampedro; J W Rowe; Daniel J Knauer
Identification of a protease inhibitor produced by astrocytes that is structurally and functionally homologous to human protease nexin-I.
Brain research 1987;415(1):40-8.
1987: R J Bridges; J Patrick Kesslak; M Nieto-Sampedro; J T Broderick; J Yu; Carl W Cotman
A L-[3H]glutamate binding site on glia: an autoradiographic study on implanted astrocytes.
Brain research 1987;415(1):163-8.
1987: Robert B Gibbs; Carl W Cotman
Factors affecting survival and outgrowth from transplants of entorhinal cortex.
Neuroscience 1987;21(3):699-706.
1987: Richard J Bridges; M Nieto-Sampedro; M Kadri; Carl W Cotman
A novel chloride-dependent L-[3H]glutamate binding site in astrocyte membranes.
Journal of neurochemistry 1987;48(6):1709-15.
1987: Kevin J Anderson; M A Borja; Carl W Cotman; John R Moffett; M A Namboodiri; Joseph H Neale
N-acetylaspartylglutamate identified in the rat retinal ganglion cells and their projections in the brain.
Brain research 1987;411(1):172-7.
1987: V K Vijayan; Carl W Cotman
Hydrocortisone administration alters glial reaction to entorhinal lesion in the rat dentate gyrus.
Experimental neurology 1987;96(2):307-20.
1987: D T Monaghan; James W Geddes; D Yao; C Chung; Carl W Cotman
[3H]TCP binding sites in Alzheimer's disease.
Neuroscience letters 1987;73(2):197-200.
1987: E Westerberg; D T Monaghan; Carl W Cotman; Tadeusz Wieloch
Excitatory amino acid receptors and ischemic brain damage in the rat.
Neuroscience letters 1987;73(2):119-24.
1987: Robert B Gibbs; D L Needels; J Yu; Carl W Cotman
Effects of entorhinal lesions on trophic activities present in rat entorhinal cortex and hippocampus as studied using primary cultures of entorhinal and septal tissues.
Journal of neuroscience research 1987;18(2):274-88.
1987: S K Pixley; M Nieto-Sampedro; Carl W Cotman
Preferential adhesion of brain astrocytes to laminin and central neurites to astrocytes.
Journal of neuroscience research 1987;18(3):402-6.
1987: M Nieto-Sampedro; J Patrick Kesslak; Robert B Gibbs; Carl W Cotman
Effects of conditioning lesions on transplant survival, connectivity, and function. Role of neurotrophic factors.
Annals of the New York Academy of Sciences 1987;495():108-19.
1986: Kevin J Anderson; D T Monaghan; Charles B Cangro; M A Namboodiri; Joseph H Neale; Carl W Cotman
Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain.
Neuroscience letters 1986;72(1):14-20.
1986: James W Geddes; H Chang-Chui; S M Cooper; Ira T Lott; Carl W Cotman
Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease.
Brain research 1986;399(1):156-61.
1986: James W Geddes; K J Anderson; Carl W Cotman
Senile plaques as aberrant sprout-stimulating structures.
Experimental neurology 1986;94(3):767-76.
1986: J P Kesslak; L Brown; C Steichen; Carl W Cotman
Adult and embryonic frontal cortex transplants after frontal cortex ablation enhance recovery on a reinforced alternation task.
Experimental neurology 1986;94(3):615-26.
1986: H J Olverman; D T Monaghan; Carl W Cotman; Jeffrey C Watkins
[3H]CPP, a new competitive ligand for NMDA receptors.
European journal of pharmacology 1986;131(1):161-2.
1986: D T Monaghan; Carl W Cotman
Identification and properties of N-methyl-D-aspartate receptors in rat brain synaptic plasma membranes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7532-6.
1986: E W Harris; Carl W Cotman
Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl D-aspartate antagonists.
Neuroscience letters 1986;70(1):132-7.
1986: Robert B Gibbs; K Anderson; Carl W Cotman
Factors affecting innervation in the CNS: comparison of three cholinergic cell types transplanted to the hippocampus of adult rats.
Brain research 1986;383(1-2):362-6.
1986: Robert B Gibbs; S K Pixley; Carl W Cotman
Transplantation of septal neurons maintained in long-term culture.
Brain research 1986;382(2):409-15.
1986: D R Stevens; Carl W Cotman
Excitatory amino acid antagonists depress transmission in hippocampal projections to the lateral septum.
Brain research 1986;382(2):437-40.
1986: E W Harris; A H Ganong; D T Monaghan; J C Watkins; Carl W Cotman
Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus.
Brain research 1986;382(1):174-7.
1986: Carl W Cotman; J A Flatman; A H Ganong; M N Perkins
Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea-pig hippocampus.
The Journal of physiology 1986;378():403-15.
1986: James W Geddes; Carl W Cotman
Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease.
Neuroscience research 1986;3(6):672-8.
1986: T J Hearn; A H Ganong; Carl W Cotman
Antagonism of lateral olfactory tract synaptic potentials in rat prepyriform cortex slices.
Brain research 1986;379(2):372-6.
1986: K J Anderson; Robert B Gibbs; Paul Salvaterra; Carl W Cotman
Ultrastructural characterization of identified cholinergic neurons transplanted to the hippocampal formation of the rat.
The Journal of comparative neurology 1986;249(2):279-92.
1986: D L Needels; M Nieto-Sampedro; Carl W Cotman
Induction of a neurite-promoting factor in rat brain following injury or deafferentation.
Neuroscience 1986;18(3):517-26.
1986: D T Monaghan; L Nguyen; Carl W Cotman
The distribution of [3H]kainate binding sites in primate hippocampus is similar to the distribution of both Ca2+-sensitive and Ca2+-insensitive [3H]kainate binding sites in rat hippocampus.
Neurochemical research 1986;11(7):1073-82.
1986: R J Bridges; T J Hearn; D T Monaghan; Carl W Cotman
A comparison of 2-amino-4-phosphonobutyric acid (AP4) receptors and [3H]AP4 binding sites in the rat brain.
Brain research 1986;375(1):204-9.
1986: A I Millaruelo; M Nieto-Sampedro; J Yu; Carl W Cotman
Neurotrophic activity in the central and peripheral nervous systems of the cat. Effects of injury.
Brain research 1986;374(1):12-20.
1986: J Patrick Kesslak; M Nieto-Sampedro; J Globus; Carl W Cotman
Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation.
Experimental neurology 1986;92(2):377-90.
1986: A H Ganong; A W Jones; J C Watkins; Carl W Cotman
Parallel antagonism of synaptic transmission and kainate/quisqualate responses in the hippocampus by piperazine-2,3-dicarboxylic acid analogs.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):930-7.
1986: K J Anderson; V R Holets; P C Mazur; R S Lasher; Carl W Cotman
Immunocytochemical localization of serotonin in the rat dentate gyrus following raphe transplants.
Brain research 1986;369(1-2):21-8.
1986: R Thompson; Robert B Gibbs; G A Ristic; Carl W Cotman; J Yu
Lack of correlation between cortical levels of choline acetyltransferase and learning scores in rats with globus pallidus lesions.
Brain research 1986;367(1-2):402-4.
1986: R Thompson; Robert B Gibbs; G A Ristic; Carl W Cotman; J Yu
Learning deficits in rats with early neurotoxic lesions to the globus pallidus, substantia nigra, median raphe or pontine reticular formation.
Physiology & behavior 1986;37(1):141-51.
1986: Carl W Cotman; D T Monaghan
Anatomical organization of excitatory amino acid receptors and their properties.
Advances in experimental medicine and biology 1986;203():237-52.
1986: A H Ganong; Carl W Cotman
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
The Journal of pharmacology and experimental therapeutics 1986;236(1):293-9.
1986: S K Pixley; Carl W Cotman
Laminin supports short-term survival of rat septal neurons in low-density, serum-free cultures.
Journal of neuroscience research 1986;15(1):1-17.
1985: James W Geddes; D T Monaghan; Carl W Cotman; Ira T Lott; R C Kim; H C Chui
Plasticity of hippocampal circuitry in Alzheimer's disease.
Science (New York, N.Y.) 1985;230(4730):1179-81.
1985: D T Monaghan; Carl W Cotman
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(11):2909-19.
1985: M Nieto-Sampedro; D L Needels; Carl W Cotman
A simple, objective method to measure the activity of factors that promote neuronal survival.
Journal of neuroscience methods 1985;15(1):37-48.
1985: M Nieto-Sampedro; R P Saneto; J de Vellis; Carl W Cotman
The control of glial populations in brain: changes in astrocyte mitogenic and morphogenic factors in response to injury.
Brain research 1985;343(2):320-8.
1985: D T Monaghan; D Yao; Carl W Cotman
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Brain research 1985;340(2):378-83.
1985: E E Mena; Carl W Cotman
Pathologic concentrations of ammonium ions block L-glutamate uptake.
Experimental neurology 1985;89(1):259-63.
1985: Robert B Gibbs; E W Harris; Carl W Cotman
Replacement of damaged cortical projections by homotypic transplants of entorhinal cortex.
The Journal of comparative neurology 1985;237(1):47-64.
1985: S R Whittemore; M Nieto-Sampedro; D L Needels; Carl W Cotman
Neuronotrophic factors for mammalian brain neurons: injury induction in neonatal, adult and aged rat brain.
Brain research 1985;352(2):169-78.
1985: E W Harris; Carl W Cotman
Effects of synaptic antagonists on perforant path paired-pulse plasticity: differentiation of pre- and postsynaptic antagonism.
Brain research 1985;334(2):348-53.
1985: Richard A Altschuler; D T Monaghan; W G Haser; Robert Wenthold; N P Curthoys; Carl W Cotman
Immunocytochemical localization of glutaminase-like and aspartate aminotransferase-like immunoreactivities in the rat and guinea pig hippocampus.
Brain research 1985;330(2):225-33.
1985: E E Mena; D T Monaghan; S R Whittemore; Carl W Cotman
Cations differentially affect subpopulations of L-glutamate receptors in rat synaptic plasma membranes.
Brain research 1985;329(1-2):319-22.
1985: D L Needels; M Nieto-Sampedro; S R Whittemore; Carl W Cotman
Neuronotrophic activity for ciliary ganglion neurons. Induction following injury to the brain of neonatal, adult, and aged rats.
Brain research 1985;350(1-2):275-84.
1985: Carl W Cotman; M Nieto-Sampedro
Progress in facilitating the recovery of function after central nervous system trauma.
Annals of the New York Academy of Sciences 1985;457():83-104.
1984: D T Monaghan; D Yao; H J Olverman; Jeffrey C Watkins; Carl W Cotman
Autoradiography of D-2-[3H]amino-5-phosphonopentanoate binding sites in rat brain.
Neuroscience letters 1984;52(3):253-8.
1984: D T Monaghan; D Yao; Carl W Cotman
Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography.
Brain research 1984;324(1):160-4.
1984: E E Mena; S R Whittemore; D T Monaghan; Carl W Cotman
Ionic regulation of glutamate binding sites.
Life sciences 1984;35(24):2427-33.
1984: E W Harris; A H Ganong; Carl W Cotman
Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors.
Brain research 1984;323(1):132-7.
1984: M Nieto-Sampedro; S R Whittemore; D L Needels; J Larson; Carl W Cotman
The survival of brain transplants is enhanced by extracts from injured brain.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(19):6250-4.
1984: Carl W Cotman; M Nieto-Sampedro
Cell biology of synaptic plasticity.
Science (New York, N.Y.) 1984;225(4668):1287-94.
1984: V R Holets; Carl W Cotman
Postnatal development of the serotonin innervation of the hippocampus and dentate gyrus following raphe implants.
The Journal of comparative neurology 1984;226(4):457-76.
1984: Carl W Cotman
In memoriam: Henry R. Mahler 1921-1983.
Journal of neurochemistry 1984;42(4):1200-2.
1984: T H Lanthorn; A H Ganong; Carl W Cotman
2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus.
Brain research 1984;290(1):174-8.
1984: Steven T DeKosky; S W Scheff; Carl W Cotman
Elevated corticosterone levels. A possible cause of reduced axon sprouting in aged animals.
Neuroendocrinology 1984;38(1):33-8.
1984: E W Harris; Carl W Cotman
Brain tissue transplantation research.
Applied neurophysiology 1984;47(1-2):9-15.
1984: Carl W Cotman; M Nieto-Sampedro; Robert B Gibbs
Enhancing the self-repairing potential of the CNS after injury.
Central nervous system trauma : journal of the American Paralysis Association 1984;1(1):3-14.
1983: T H Lanthorn; Carl W Cotman
Relative potency of analogues of excitatory amino acids on hippocampal CA1 neurons.
Neuropharmacology 1983;22(12A):1343-8.
1983: D T Monaghan; M C McMills; A Richard Chamberlin; Carl W Cotman
Synthesis of [3H]2-amino-4-phosphonobutyric acid and characterization of its binding to rat brain membranes: a selective ligand for the chloride/calcium-dependent class of L-glutamate binding sites.
Brain research 1983;278(1-2):137-44.
1983: D T Monaghan; V R Holets; D W Toy; Carl W Cotman
Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites.
Nature 1983;306(5939):176-9.
1983: M Nieto-Sampedro; M Manthrope; G Barbin; S Varon; Carl W Cotman
Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(11):2219-29.
1983: S R Whittemore; E E Mena; D T Monaghan; Carl W Cotman
Regional distribution and ionic requirement of Cl-/Ca2+-activated and Cl-/Ca2+-independent glutamate receptors in rat brain.
Brain research 1983;277(1):99-107.
1983: A H Ganong; T H Lanthorn; Carl W Cotman
Kynurenic acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord.
Brain research 1983;273(1):170-4.
1983: G E Fagg; E E Mena; D T Monaghan; Carl W Cotman
Freezing eliminates a specific population of L-glutamate receptors in synaptic membranes.
Neuroscience letters 1983;38(2):157-62.
1983: M Manthorpe; M Nieto-Sampedro; stephen drake skaper; E R Lewis; G Barbin; F M Longo; Carl W Cotman; S Varon
Neuronotrophic activity in brain wounds of the developing rat. Correlation with implant survival in the wound cavity.
Brain research 1983;267(1):47-56.
1983: G E Fagg; A C Foster; E E Mena; Carl W Cotman
Chloride and calcium ions separate L-glutamate receptor populations in synaptic membranes.
European journal of pharmacology 1983;88(1):105-10.
1983: J F Koerner; Carl W Cotman
A microperfusion chamber for brain slice pharmacology.
Journal of neuroscience methods 1983;7(3):243-51.
1983: J S Wendt; G E Fagg; Carl W Cotman
Regeneration of rat hippocampal fimbria fibers after fimbria transection and peripheral nerve or fetal hippocampal implantation.
Experimental neurology 1983;79(2):452-61.
1983: V K Vijayan; Carl W Cotman
Lysosomal enzyme changes in young and aged control and entorhinal-lesioned rats.
Neurobiology of aging 1983;4(1):13-23.
1983: Carl W Cotman; S F Hoff
Synapse repair in the hippocampus: the effects of aging.
Birth defects original article series 1983;19(4):119-34.
1983: E W Harris; Carl W Cotman
Effects of acidic amino acid antagonists on paired-pulse potentiation at the lateral perforant path.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1983;52(3):455-60.
1983: G E Fagg; E E Mena; Carl W Cotman
L-glutamate receptor populations in synaptic membranes: effects of ions and pharmacological characteristics.
Advances in biochemical psychopharmacology 1983;37():199-209.
1983: E R Lewis; Carl W Cotman
Neurotransmitter characteristics of brain grafts: striatal and septal tissues form the same laminated input to the hippocampus.
Neuroscience 1983;8(1):57-66.
1982: A H Ganong; Carl W Cotman
Acidic amino acid antagonists of lateral perforant path synaptic transmission: agonist-antagonist interactions in the dentate gyrus.
Neuroscience letters 1982;34(2):195-200.
1982: D T Monaghan; Carl W Cotman
The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography.
Brain research 1982;252(1):91-100.
1982: M N Sampedro; C M Bussineau; Carl W Cotman
Turnover of brain postsynaptic densities after selective deafferentation: detection by means of an antibody to antigen PSD-95.
Brain research 1982;251(2):211-20.
1982: J F Koerner; Carl W Cotman
Response of Schaffer collateral-CA 1 pyramidal cell synapses of the hippocampus to analogues of acidic amino acids.
Brain research 1982;251(1):105-15.
1982: M Nieto-Sampedro; S F Hoff; Carl W Cotman
Perforated postsynaptic densities: probable intermediates in synapse turnover.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(18):5718-22.
1982: M Nieto-Sampedro; E R Lewis; Carl W Cotman; M Manthorpe; stephen drake skaper; G Barbin; F M Longo; S Varon
Brain injury causes a time-dependent increase in neuronotrophic activity at the lesion site.
Science (New York, N.Y.) 1982;217(4562):860-1.
1982: G E Fagg; A C Foster; E W Harris; T H Lanthorn; Carl W Cotman
Structure--activity relationships of L-glutamate receptor ligands: role of the omega-acidic terminal.
Neuroscience letters 1982;31(1):59-64.
1982: E E Mena; G E Fagg; Carl W Cotman
Chloride ions enhance L-glutamate binding to rat brain synaptic membranes.
Brain research 1982;243(2):378-81.
1982: G E Fagg; A C Foster; E E Mena; Carl W Cotman
Chloride and calcium ions reveal a pharmacologically distinct population of L-glutamate binding sites in synaptic membranes: correspondence between biochemical and electrophysiological data.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(7):958-65.
1982: A C Foster; G E Fagg; E W Harris; Carl W Cotman
Regulation of glutamate receptors: possible role of phosphatidylserine.
Brain research 1982;242(2):374-7.
1982: M Nieto-Sampedro; C M Bussineau; Carl W Cotman
Isolation, morphology, and protein and glycoprotein composition of synaptic junctional fractions from the brain of lower vertebrates: antigen PSD-95 as a junctional marker.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(6):722-34.
1982: S W Scheff; Carl W Cotman
Chronic glucocorticoid therapy alters axon sprouting in the hippocampal dentate gyrus.
Experimental neurology 1982;76(3):644-54.
1982: E E Mena; Carl W Cotman
Synaptic cleft glycoproteins contain homologous amino acid sequences.
Science (New York, N.Y.) 1982;216(4544):422-4.
1982: S F Hoff; S W Scheff; Carl W Cotman
Lesion-induced synaptogenesis in the dentate gyrus of aged rats: II. Demonstration of an impaired degeneration clearing response.
The Journal of comparative neurology 1982;205(3):253-9.
1982: S F Hoff; S W Scheff; L S Benardo; Carl W Cotman
Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density.
The Journal of comparative neurology 1982;205(3):246-52.
1982: D T Monaghan; E E Mena; Carl W Cotman
The effect of entorhinal cortical ablation on the distribution of muscarinic cholinergic receptors in the rat hippocampus.
Brain research 1982;234(2):480-5.
1982: E R Lewis; Carl W Cotman
Mechanisms of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. III. Competitive interactions.
Brain research 1982;233(1):29-44.
1982: E R Lewis; Carl W Cotman
Mechanisms of septal lamination in the developing hippocampus analyzed by outgrowth of fibers from septal implants. II. Absence of guidance by degenerative debris.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(1):66-77.
1982: R L Beach; S L Bathgate; Carl W Cotman
Identification of cell types in rat hippocampal slices maintained in organotypic cultures.
Brain research 1982;255(1):3-20.
1982: Carl W Cotman; M Nieto-Sampedro
Brain function, synapse renewal, and plasticity.
Annual review of psychology 1982;33():371-401.
1981: A C Foster; G E Fagg; E E Mena; Carl W Cotman
L-glutamate and L-aspartate bind to separate sites in rat brain synaptic membranes.
Brain research 1981;229(1):246-50.
1981: G E Fagg; S W Scheff; Carl W Cotman
Axonal sprouting at the neuromuscular junction of adult and aged rats.
Experimental neurology 1981;74(3):847-54.
1981: E E Mena; A C Foster; G E Fagg; Carl W Cotman
Identification of synapse specific components: synaptic glycoproteins, proteins, and transmitter binding sites.
Journal of neurochemistry 1981;37(6):1557-66.
1981: R L Beach; P T Kelly; J A Babitch; Carl W Cotman
Identification of myosin in isolated synaptic junctions.
Brain research 1981;225(1):75-93.
1981: T H Lanthorn; Carl W Cotman
Baclofen selectively inhibits excitatory synaptic transmission in the hippocampus.
Brain research 1981;225(1):171-8.
1981: S F Hoff; S W Scheff; A Y Kwan; Carl W Cotman
A new type of lesion-induced synaptogenesis: II. The effect of aging on synaptic turnover in non-denervated zones.
Brain research 1981;222(1):15-27.
1981: S F Hoff; S W Scheff; A Y Kwan; Carl W Cotman
A new type of lesion-induced synaptogenesis: I. Synaptic turnover in non-denervated zones of the dentate gyrus in young adult rats.
Brain research 1981;222(1):1-13.
1981: M N Sampedro; C M Bussineau; Carl W Cotman
Postsynaptic density antigens: preparation and characterization of an antiserum against postsynaptic densities.
The Journal of cell biology 1981;90(3):675-86.
1981: J F Koerner; Carl W Cotman
Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex.
Brain research 1981;216(1):192-8.
1981: Carl W Cotman; M Nieto-Sampedro; E W Harris
Synapse replacement in the nervous system of adult vertebrates.
Physiological reviews 1981;61(3):684-784.
1981: A C Foster; E E Mena; G E Fagg; Carl W Cotman
Glutamate and aspartate binding sites are enriched in synaptic junctions isolated from rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(6):620-5.
1981: J V Nadler; B W Perry; C Gentry; Carl W Cotman
Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid.
The Journal of comparative neurology 1981;196(4):549-69.
1981: M Nieto-Sampedro; C M Bussineau; Carl W Cotman
Optimal concentration of iodonitrotetrazolium for the isolation of junctional fractions from rat brain.
Neurochemical research 1981;6(3):307-20.
1981: P T Kelly; Carl W Cotman
Developmental changes in morphology and molecular composition of isolated synaptic junctional structures.
Brain research 1981;206(2):251-7.
1981: E E Mena; D T Monaghan; Carl W Cotman
Lesion-induced alterations of lectin binding sites in the rat dentate gyrus.
Neuroscience 1981;6(10):1975-83.
1981: A C Foster; E E Mena; D T Monaghan; Carl W Cotman
Synaptic localization of kainic acid binding sites.
Nature 1981;289(5793):73-5.
1981: Carl W Cotman; A Foster; T Lanthorn
An overview of glutamate as a neurotransmitter.
Advances in biochemical psychopharmacology 1981;27():1-27.
1980: S W Scheff; L S Benardo; Carl W Cotman
Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal.
Brain research 1980;199(1):21-38.
1980: E R Lewis; Carl W Cotman
Mechanisms of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. I. Positional and temporal factors.
Brain research 1980;196(2):307-30.
1980: J V Nadler; B W Perry; C Gentry; Carl W Cotman
Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid.
The Journal of comparative neurology 1980;192(2):333-59.
1980: J V Nadler; B W Perry; C Gentry; Carl W Cotman
Loss and reacquisition of hippocampal synapses after selective destruction of CA3-CA4 afferents with kainic acid.
Brain research 1980;191(2):387-403.
1980: E R Lewis; Carl W Cotman
Factors specifying the development of synapse number in the rat dentate gyrus: effects of partial target loss.
Brain research 1980;191(1):35-52.
1980: M Nieto-Sampedro; D Shelton; Carl W Cotman
Specific binding of kainic acid to purified subcellular fractions from rat brain.
Neurochemical research 1980;5(6):591-604.
1980: E R Lewis; J C Mueller; Carl W Cotman
Neonatal septal implants: development of afferent lamination in the rat dentate gyrus.
Brain research bulletin 1980;5(3):217-21.
1980: S W Scheff; L S Benardo; Carl W Cotman
Hydrocortison administration retards axon sprouting in the rat dentate gyrus.
Experimental neurology 1980;68(1):195-201.
1980: J V Nadler; B W Perry; Carl W Cotman
Interaction with CA4-derived fibers accounts for distribution of septohippocampal fibers in rat fascia dentata after entorhinal lesion.
Experimental neurology 1980;68(1):185-94.
1980: J V Nadler; B W Perry; Carl W Cotman
Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid.
Brain research 1980;182(1):1-9.
1980: J V Nadler; D L Shelton; B W Perry; Carl W Cotman
Regional distribution of [3H]kainic acid after intraventricular injection.
Life sciences 1980;26(2):133-8.
1980: D Goldowitz; Carl W Cotman
Do neurotrophic interactions control synapse formation in the adult rat brain?
Brain research 1980;181(2):325-44.
1980: D Goldowitz; Carl W Cotman
Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study.
Neuroscience 1980;5(12):2163-74.
1979: W F White; J V Nadler; Carl W Cotman
Analysis of short-term plasticity at the perforant path-granule cell synapse.
Brain research 1979;178(1):41-53.
1979: D Goldowitz; S W Scheff; Carl W Cotman
The specificity of reactive synaptogenesis: a comparative study in the adult rat hippocampal formation.
Brain research 1979;170(3):427-41.
1979: A Hamberger; G H Chiang; E Sandoval; Carl W Cotman
Glutamate as a CNS transmitter. II. Regulation of synthesis in the releasable pool.
Brain research 1979;168(3):531-41.
1979: A C Hamberger; G H Chiang; E S Nylén; S W Scheff; Carl W Cotman
Glutamate as a CNS transmitter. I. Evaluation of glucose and glutamine as precursors for the synthesis of preferentially released glutamate.
Brain research 1979;168(3):513-30.
1979: J A Rostas; P T Kelly; R H Pesin; Carl W Cotman
Protein and glycoprotein composition of synaptic junctions prepared from discrete synaptic regions and different species.
Brain research 1979;168(1):151-67.
1979: J V Nadler; D L Shelton; Carl W Cotman
Lesion-induced plasticity of high affinity choline uptake in the developing rat fascia dentata.
Brain research 1979;164():207-16.
1979: W F White; J V Nadler; Carl W Cotman
The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro.
Brain research 1979;164():177-94.
1979: D L Shelton; J V Nadler; Carl W Cotman
Development of high affinity choline uptake and associated acetylcholine synthesis in the rat fascia dentata.
Brain research 1979;163(2):263-75.
1979: P T Kelly; Carl W Cotman; M Largen
Cyclic AMP-stimulated protein kinases at brain synaptic junctions.
The Journal of biological chemistry 1979;254(5):1564-75.
1979: Carl W Cotman
Specificity of synaptic growth in brain: remodeling induced by kainic acid lesions.
Progress in brain research 1979;51():203-15.
1979: J W Haycock; W B Levy; L A Denner; Carl W Cotman
Stimulus-secretion coupling processes in brain: dependence upon extracellular calcium concentration.
Neuroscience 1979;4(9):1341-6.
1979: Carl W Cotman; S W Scheff
Compensatory synapse growth in aged animals after neuronal death.
Mechanisms of ageing and development 1979;9(1-2):103-17.
1978: S W Scheff; L S Benardo; Carl W Cotman
Lesion-induced vascular changes in the dentate gyrus following removal of the entorhinal cortex in adult rats.
Experimental neurology 1978;62(3):815-20.
1978: S W Scheff; L S Bernardo; Carl W Cotman
Decrease in adrenergic axon sprouting in the senescent rat.
Science (New York, N.Y.) 1978;202(4369):775-8.
1978: A Hamberger; J T Cummins; E Keller; Carl W Cotman
Glutamate secretion and NAD(P)H levels during calcium-dependent depolarization of slices of the dentate gyrus.
Brain research 1978;156(2):253-64.
1978: J W Haycock; W B Levy; Carl W Cotman
Stimulation-dependent depression of neurotransmitter release in brain: [Ca2+]o dependence.
Brain research 1978;155(1):192-5.
1978: P T Kelly; Carl W Cotman
Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide.
The Journal of cell biology 1978;79(1):173-83.
1978: W F White; J V Nadler; Carl W Cotman
A perfusion chamber for the study of CNS physiology and pharmacology in vitro.
Brain research 1978;152(3):591-6.
1978: D Goldwitz; Carl W Cotman
Induction of extensive fimbrial branching in the adult rat brain.
Nature 1978;275(5675):64-7.
1978: S W Scheff; L S Benardo; Carl W Cotman
Effect of serial lesions on sprouting in the dentate gyrus: onset and decline of the catalytic effect.
Brain research 1978;150(1):45-53.
1978: J V Nadler; W F White; K W Vaca; B W Perry; Carl W Cotman
Biochemical correlates of transmission mediated by glutamate and aspartate.
Journal of neurochemistry 1978;31(1):147-55.
1978: J W Haycock; W B Levy; L A Denner; Carl W Cotman
Effects of elevated [K+]O on the release of neurotransmitters from cortical synaptosomes: efflux or secretion?
Journal of neurochemistry 1978;30(5):1113-25.
1978: A Hamberger; G Chiang; E S Nylén; S W Scheff; Carl W Cotman
Stimulus evoked increase in the biosynthesis of the putative neurotransmitter glutamate in the hippocampus.
Brain research 1978;143(3):549-55.
1978: M E Sandoval; P Horch; Carl W Cotman
Evaluation of glutamate as a hippocampal neurotransmitter: glutamate uptake and release from synaptosomes.
Brain research 1978;142(2):285-99.
1978: J V Nadler; Carl W Cotman
Interactions between afferents to the dentate gyrus after entorhinal lesion during development: long-term regulation of choline acetyl-transferase activity.
Brain research 1978;142(1):174-81.
1978: J V Nadler; B W Perry; Carl W Cotman
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells.
Nature 1978;271(5646):676-7.
1978: M E Sandoval; Carl W Cotman
Evaluation of glutamate as a neurotransmitter of cerebellar parallel fibers.
Neuroscience 1978;3(2):199-206.
1978: J W Haycock; W F White; Carl W Cotman
Differences in alkaline earth stimulation of neurotransmitter release from isolated brain synaptosomes.
Naunyn-Schmiedeberg's archives of pharmacology 1978;301(3):175-9.
1977: J W Haycock; W F White; J L McGaugh; Carl W Cotman
Enhanced stimulus--secretion coupling from brains of aged mice.
Experimental neurology 1977;57(3):873-82.
1977: W F White; J V Nadler; A Hamberger; Carl W Cotman; J T Cummins
Glutamate as transmitter of hippocampal perforant path.
Nature 1977;270(5635):356-7.
1977: O Steward; W F White; Carl W Cotman
Potentiation of the excitatory synaptic action of commissural, associational and entorhinal afferents to dentate granule cells.
Brain research 1977;134(3):551-60.
1977: S W Scheff; Carl W Cotman
Recovery of spontaneous alternation following lesions of the entorhinal cortex in adult rats: possible correlation to axon sprouting.
Behavioral biology 1977;21(2):286-93.
1977: K S Lee; E J Stanford; Carl W Cotman; G S Lynch
Ultrastructural evidence for bouton proliferation in the partially deafferented dentate gyrus of the adult rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1977;29(3-4):475-85.
1977: S Scheff; I Benardo; Carl W Cotman
Progressive brain damage accelerates axon sprouting in the adult rat.
Science (New York, N.Y.) 1977;197(4305):795-7.
1977: Shu-Hui C. Yen; R K Liem; P T Kelly; Carl W Cotman; Michael L. Shelanski
Membrane linked proteins at CNS synapses.
Brain research 1977;132(1):172-5.
1977: J V Nadler; W F White; K W Vaca; Carl W Cotman
Calcium-dependent gamma-aminobutyrate release by interneurons of rat hippocampal regions: lesion-induced plasticity.
Brain research 1977;131(2):241-58.
1977: Carl W Cotman; C Gentry; O Steward
Synaptic replacement in the dentate gyrus after unilateral entorhinal lesion: electron microscopic analysis of the extent of replacement of synapses by the remaining entorhinal cortex.
Journal of neurocytology 1977;6(4):455-64.
1977: J V Nadler; W F White; K W Vaca; D A Redburn; Carl W Cotman
Characterization of putative amino acid transmitter release from slices of rat dentate gyrus.
Journal of neurochemistry 1977;29(2):279-90.
1977: J A Rostas; P T Kelly; Carl W Cotman
The identification of membrane glycocomponents in polyacrylamide gels: a rapid method using 125I-labeled lectins.
Analytical biochemistry 1977;80(2):366-72.
1977: H Feit; P Kelly; Carl W Cotman
Identification of a protein related to tubulin in the postsynaptic density.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(3):1047-51.
1977: J V Nadler; Carl W Cotman; C Paoletti; G S Lynch
Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. II. Effects of partial entorhinal and simultaneous multiple lesions.
The Journal of comparative neurology 1977;171(4):589-604.
1977: J V Nadler; Carl W Cotman; G S Lynch
Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. I. Time course after complete unilateral entorhinal lesion at various ages.
The Journal of comparative neurology 1977;171(4):561-87.
1977: Rebekah Loy; G Lynch; Carl W Cotman
Development of afferent lamination in the fascia dentata of the rat.
Brain research 1977;121(2):229-43.
1977: P T Kelly; Carl W Cotman
Identification of glycoproteins and proteins at synapses in the central nervous system.
The Journal of biological chemistry 1977;252(2):786-93.
1977: J W Haycock; W B Levy; Carl W Cotman
Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release.
Biochemical pharmacology 1977;26(2):159-61.
1977: G Lynch; C Gall; Carl W Cotman
Temporal parameters of axon "sprouting" in the brain of the adult rat.
Experimental neurology 1977;54(1):179-83.
1976: P T Kelly; Carl W Cotman
Intermolecular disulfide bonds at central nervous system synaptic junctions.
Biochemical and biophysical research communications 1976;73(4):858-64.
1976: Carl W Cotman; J W Haycock; W B Levy
On the functional coupling of neurotransmitter uptake and release in brain.
British journal of pharmacology 1976;58(4):569-72.
1976: O Steward; C W White; Carl W Cotman; G Lynch
Potentiation of excitatory synaptic transmission in the normal and in the reinnervated dentate gyrus of the rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1976;26(4):423-41.
1976: J R West; S A Deadwyler; Carl W Cotman; G S Lynch
An experimental test of diaschisis.
Behavioral biology 1976;18(3):419-25.
1976: P Kelly; Carl W Cotman; C Gentry; G L Nicolson
Distribution and mobility of lectin receptors on synaptic membranes of identified neurons in the central nervous system.
The Journal of cell biology 1976;71(2):487-96.
1976: W B Levy; J W Haycock; Carl W Cotman
Stimulation-dependent depression of readily releasable neurotransmitter pools in brain.
Brain research 1976;115(2):243-56.
1976: D A Matthews; Carl W Cotman; G Lynch
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts.
Brain research 1976;115(1):23-41.
1976: D A Matthews; Carl W Cotman; G Lynch
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration.
Brain research 1976;115(1):1-21.
1976: L Churchill; Carl W Cotman; Gary Banker; P Kelly; L Shannon
Carbohydrate composition of central nervous system synapses. Analysis of isolated synaptic junctional complexes and postsynaptic densities.
Biochimica et biophysica acta 1976;448(1):57-72.
1976: W F White; D Goldowitz; G Lynch; Carl W Cotman
Electrophysiological analysis of the projection from the contralateral entorhinal cortex to the dentate gyrus in normal rats.
Brain research 1976;114(2):201-9.
1976: O Steward; Carl W Cotman; G Lynch
A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions.
Brain research 1976;114(2):181-200.
1976: G Lynch; C Gall; G Rose; Carl W Cotman
Changes in the distribution of the dentate gyrus associational system following unilateral or bilateral entorhinal lesions in the adult rat.
Brain research 1976;110(1):57-71.
1976: H J Spencer; V K Gribkoff; Carl W Cotman; G S Lynch
GDEE antagonism of iontophoretic amino acid excitations in the intact hippocampus and in the hippocampal slice preparation.
Brain research 1976;105(3):471-81.
1976: J V Nadler; K W Vaca; W F White; G S Lynch; Carl W Cotman
Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents.
Nature 1976;260(5551):538-40.
1976: F E Dudek; S A Deadwyler; Carl W Cotman; G Lynch
Intracellular responses from granule cell layer in slices of rat hippocampus: perforant path synapse.
Journal of neurophysiology 1976;39(2):384-93.
1976: D A Redburn; D Shelton; Carl W Cotman
Calcium-dependent release of exogenously loaded gamma-amino-[U-14C]butyrate from synaptosomes: time course of stimulation by potassium, veratridine, and the calcium ionophore, A23187.
Journal of neurochemistry 1976;26(2):297-303.
1976: G Rose; G Lynch; Carl W Cotman
Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus.
Brain research bulletin 1976;1(1):87-92.
1976: S A Deadwyler; V Gribkoff; Carl W Cotman; G Lynch
Long lasting changes in the spontaneous activity of hippocampal neurons following stimulation of the entorhinal cortex.
Brain research bulletin 1976;1(1):1-7.
1976: Carl W Cotman; J W Haycock; W F White
Stimulus-secretion coupling processes in brain: analysis of noradrenaline and gamma-aminobutyric acid release.
The Journal of physiology 1976;254(2):475-505.
1976: Carl W Cotman
Lesion-induced synaptogenesis in brain: a study of dynamic changes in neuronal membrane specializations.
Journal of supramolecular structure 1976;4(3):319-27.
1975: J R West; S Deadwyler; Carl W Cotman; G Lynch
Time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats.
Brain research 1975;97(2):215-33.
1975: S A Deadwyler; J R West; Carl W Cotman; G Lynch
Physiological studies of the reciprocal connections between the hippocampus and entorhinal cortex.
Experimental neurology 1975;49(1 Pt 1):35-57.
1975: J R West; S A Deadwyler; Carl W Cotman; G Lynch
A dual marking technique for microelectrode tracks and localization recording sites.
Electroencephalography and clinical neurophysiology 1975;39(4):407-10.
1975: D A Redburn; J Biela; D L Shelton; Carl W Cotman
Stimulus secretion coupling in vitro: a rapid perfusion apparatus for monitoring efflux of transmitter substances from tissue samples.
Analytical biochemistry 1975;67(1):268-78.
1975: D Goldowitz; W F White; O Steward; G Lynch; Carl W Cotman
Anatomical evidence for a projection from the entorhinal cortex to the contralateral dentate gyrus of the rat.
Experimental neurology 1975;47(3):433-41.
1975: S A Deadwyler; F E Dudek; Carl W Cotman; G Lynch
Intracellular responses of rat dentate granule cells in vitro: posttetanic potentiation to perforant path stimulation.
Brain research 1975;88(1):80-5.
1975: R R Drucker-Colín; C W Spanis; Carl W Cotman; J L McGaugh
Changes in protein levels in perfusates of freely moving cats: relation to behavioral state.
Science (New York, N.Y.) 1975;187(4180):963-5.
1975: R W Russell; David H Overstreet; Carl W Cotman; V G Carson; L Churchill; F W Dalglish; B J Vasquez
Experimental tests of hypotheses about neurochemical mechanisms underlying behavioral tolerance to the anticholinesterase, diisopropyl fluorophosphate.
The Journal of pharmacology and experimental therapeutics 1975;192(1):73-85.
1975: S A Deadwyler; J R West; Carl W Cotman; G S Lynch
A neurophysiological analysis of commissural projections to dentate gyrus of the rat.
Journal of neurophysiology 1975;38(1):167-84.
1974: T J Chippendale; Carl W Cotman; M D Kozar; G S Lynch
Analysis of acetylcholinesterase synthesis and transport in the rat hippocampus: recovery of acetylcholinesterase activity in the septum and hippocampus after administration of diisopropylfluorophosphate.
Brain research 1974;81(3):485-96.
1974: Gary Banker; L Churchill; Carl W Cotman
Proteins of the postsynaptic density.
The Journal of cell biology 1974;63(2 Pt 1):456-65.
1974: J V Nadler; Carl W Cotman; G S Lynch
Biochemical plasticity of short-axon interneurons: increased glutamate decarboxylase activity in the denervated area of rat dentate gyrus following entorhinal lesion.
Experimental neurology 1974;45(2):403-13.
1974: Carl W Cotman; Gary Banker; L Churchill; D Taylor
Isolation of postsynaptic densities from rat brain.
The Journal of cell biology 1974;63(2 Pt 1):441-55.
1974: J V Nadler; Carl W Cotman; G S Lynch
Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.
Brain research 1974;79(3):465-75.
1974: Carl W Cotman; D Taylor
Localization and characterization of concanavalin A receptors in the synaptic cleft.
The Journal of cell biology 1974;62(1):236-42.
1974: D A Redburn; Carl W Cotman
Calcium-dependent release of (14C)GABA from vinblastine and colchicine treated synaptosomes.
Brain research 1974;73(3):550-7.
1974: W B Levy; J W Haycock; Carl W Cotman
Effects of polyvalent cations on stimulus-coupled secretion of (14C)-gamma-aminobutyric acid from isolated brain synaptosomes.
Molecular pharmacology 1974;10(3):438-49.
1974: O Steward; Carl W Cotman; G S Lynch
Growth of a new fiber projection in the brain of adult rats: Re-innervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1974;20(1):45-66.
1974: G Lynch; B Stanfield; T Parks; Carl W Cotman
Evidence for selective post-lesion axonal growth in the dentate gyrus of the rat.
Brain research 1974;69(1):1-11.
1974: J G Parnavelas; G Lynch; Nicholas Brecha; Carl W Cotman; A Globus
Spine loss and regrowth in hippocampus following deafferentation.
Nature 1974;248(443):71-3.
1974: G Lynch; C Gall; P Mensah; Carl W Cotman
Horseradish peroxidase histochemistry: a new method for tracing efferent projections in the central nervous system.
Brain research 1974;65(3):373-80.
1974: J V Nadler; D A Matthews; Carl W Cotman; G S Lynch
Development of cholinergic innervation in the hippocampal formation of the rat. II. Quantitative changes in choline acetyltransferase and acetylcholinesterase activities.
Developmental biology 1974;36(1):142-54.
1974: D A Matthews; J V Nadler; G S Lynch; Carl W Cotman
Development of cholinergic innervation in the hippocampal formation of the rat. I. Histochemical demonstration of acetylcholinesterase activity.
Developmental biology 1974;36(1):130-41.
1974: Carl W Cotman
Isolation of synaptosomal and synaptic plasma membrane fractions.
Methods in enzymology 1974;31():445-52.
1973: B Crain; Carl W Cotman; D Taylor; G Lynch
A quantitative electron microscopic study of synaptogenesis in the dentate gyrus of the rat.
Brain research 1973;63():195-204.
1973: O Steward; Carl W Cotman; G Lynch
The nature of increased histochemical deposition of INT formazan in fields of degenerating synaptic terminals.
Brain research 1973;63():183-93.
1973: J V Nadler; Carl W Cotman; G S Lynch
Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion.
Brain research 1973;63():215-20.
1973: L Churchill; Gary Banker; Carl W Cotman
Gradient design to optimize rate zonal separations.
Analytical biochemistry 1973;56(2):370-82.
1973: Carl W Cotman; D A Matthews; D Taylor; G Lynch
Synaptic rearrangement in the dentate gyrus: histochemical evidence of adjustments after lesions in immature and adult rats.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(12):3473-7.
1973: O Steward; Carl W Cotman; G S Lynch
Re-establishment of electrophysiologically functional entorhinal cortical input to the dentate gyrus deafferented by ipsilateral entorhinal lesions: innervation by the contralateral entorhinal cortex.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1973;18(4):396-414.
1973: S Mosko; G Lynch; Carl W Cotman
The distribution of septal projections to the hippocampus of the rat.
The Journal of comparative neurology 1973;152(2):163-74.
1973: G Lynch; B Stanfield; Carl W Cotman
Developmental differences in post-lesion axonal growth in the hippocampus.
Brain research 1973;59():155-68.
1973: W B Levy; D A Redburn; Carl W Cotman
Stimulus-coupled secretion of gamma-aminobutyric acid from rat brain synaptosomes.
Science (New York, N.Y.) 1973;181(4100):676-8.
1973: G Lynch; R L Smith; P Mensah; Carl W Cotman
Tracing the dentate gyrus mossy fiber system with horseradish peroxidase histochemistry.
Experimental neurology 1973;40(2):516-24.
1973: O Steward; G Lynch; Carl W Cotman
Histochemical detection of orthograde degeneration in the central nervous system of the rat.
Brain research 1973;54():65-73.
1973: G S Lynch; S Mosko; T Parks; Carl W Cotman
Relocation and hyperdevelopment of the dentate gyrus commissural system after entorhinal lesions in immature rats.
Brain research 1973;50(1):174-8.
1973: L Churchill; Carl W Cotman
Analytical zonal centrifugation of synaptosomes and mitochondria from rat brain homogenates.
Neurobiology 1973;3(5):311-9.
1972: Carl W Cotman; D Taylor
Isolation and structural studies on synaptic complexes from rat brain.
The Journal of cell biology 1972;55(3):696-711.
1972: Gary Banker; Carl W Cotman
Measurement of free electrophoretic mobility and retardation coefficient of protein-sodium dodecyl sulfate complexes by gel electrophoresis. A method to validate molecular weight estimates.
The Journal of biological chemistry 1972;247(18):5856-61.
1972: L C Doyle; Carl W Cotman
Analysis of myelin-synaptosomal interactions in sucrose and Ficoll-sucrose gradients.
Analytical biochemistry 1972;49(1):29-36.
1972: Gary Banker; B Crain; Carl W Cotman
Molecular weights of the polypeptide chains of synaptic plasma membranes.
Brain research 1972;42(2):508-13.
1972: G Lynch; D A Matthews; S Mosko; T Parks; Carl W Cotman
Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions.
Brain research 1972;42(2):311-8.
1972: H R Herschman; Carl W Cotman; D A Matthews
Serologic specificities of brain subcellular organelles. I. Antisera to synaptosomal fractions.
Journal of immunology (Baltimore, Md. : 1950) 1972;108(5):1362-9.
1972: A Costin; Carl W Cotman; D R Hafemann; H R Herschmann
Effect of antibrain synaptosomal fraction serum and complement on evoked potentials and impedance.
Experientia 1972;28(4):411-2.
1971: Carl W Cotman; R E McCaman; S A Dewhurst
Subsynaptosomal distribution of enzymes involved in the metabolism of lipids.
Biochimica et biophysica acta 1971;249(2):395-405.
1971: Carl W Cotman; D A Matthews
Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization.
Biochimica et biophysica acta 1971;249(2):380-94.
1971: Carl W Cotman; Gary Banker; W Levy; D Taylor
An ultrastructural and chemical analysis of the effect of triton X-100 on synaptic plasma membranes.
Biochimica et biophysica acta 1971;249(2):406-18.
1971: Carl W Cotman; Gary Banker; S F Zornetzer; J L McGaugh
Electroshock effects on brain protein synthesis: relation to brain seizures and retrograde amnesia.
Science (New York, N.Y.) 1971;173(3995):454-6.
1971: Carl W Cotman; D A Taylor
Autoradiographic analysis of protein synthesis in synaptosomal fractions.
Brain research 1971;29(2):366-72.
1971: T Nielsen; Carl W Cotman
The binding of diphenylhydantoin to brain and subcellular fractions.
European journal of pharmacology 1971;14(4):344-50.
1971: Gary Banker; Carl W Cotman
Characteristics of different amino acids as protein precursors in mouse brain: advantages of certain carboxyl-labeled amino acids.
Archives of biochemistry and biophysics 1971;142(2):565-73.
1971: Carl W Cotman; H Herschman; D Taylor
Subcellular fractionation of cultured glial cells.
Journal of neurobiology 1971;2(2):169-80.
1970: Carl W Cotman; D A Flansburg
An analytical micro-method for electron microscopic study of the composition and sedimentation properties of subcellular fractions.
Brain research 1970;22(1):152-6.
1970: Carl W Cotman; D H Brown; B W Harrell; N G Anderson
Analytical differential centrifugation: an analysis of the sedimentation properties of synaptosomes, mitochondria and lysosomes from rat brain homogenates.
Archives of biochemistry and biophysics 1970;136(2):436-47.
1969: Carl W Cotman; M L Blank; A Moehl; F Snyder
Lipid composition of synaptic plasma membranes isolated from rat brain by zonal centrifugation.
Biochemistry 1969;8(11):4606-12.
1969: H Birch; Carl W Cotman; R F Thompson
Technique and instrumentation in physiological psychology.
The American psychologist 1969;24(3):264-7.
1968: Carl W Cotman; H R Mahler; N G Anderson
Isolation of a membrane fraction enriched in nerve-end membranes from rat brain by zonal cetrifugation.
Biochimica et biophysica acta 1968;163(2):272-5.
1968: Carl W Cotman; H R Mahler; T E Hugli
Isolation and characterization of insoluble proteins of the synaptic plasma membrane.
Archives of biochemistry and biophysics 1968;126(3):821-37.
1967: Carl W Cotman; H R Mahler
Resolution of insoluble proteins in rat brain subcellular fractions.
Archives of biochemistry and biophysics 1967;120(2):384-96.
1966: J Jayaraman; Carl W Cotman; H R Mahler; C W Sharp
Biochemical correlates of respiratory deficiency. VII. Glucose repression.
Archives of biochemistry and biophysics 1966;116(1):224-51.