Carl Cotman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Anatomy

Disorders

Chemicals & Drugs

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Acharya Munjal M; Christie Lori-Ann; Lan Mary L; Donovan Peter J; Cotman Carl W; Fike John R; Limoli Charles L
Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells.
Head E; Nukala V N; Fenoglio K A; Muggenburg B A; Cotman C W; Sullivan P G
Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging.
Nichol Kathryn; Deeny Sean P; Seif Joseph; Camaclang Kevin; Cotman Carl W
Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Carl Cotman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Acharya Munjal M; Christie Lori-Ann; Lan Mary L; Donovan Peter J; Cotman Carl W; Fike John R; Limoli Charles L
Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):19150-5.
2009: Head E; Nukala V N; Fenoglio K A; Muggenburg B A; Cotman C W; Sullivan P G
Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging.
Experimental neurology 2009;220(1):171-6.
2009: Nichol Kathryn; Deeny Sean P; Seif Joseph; Camaclang Kevin; Cotman Carl W
Exercise improves cognition and hippocampal plasticity in APOE epsilon4 mice.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009;5(4):287-94.
2009: Taylor Anne M; Berchtold Nicole C; Perreau Victoria M; Tu Christina H; Li Jeon Noo; Cotman Carl W
Axonal mRNA in uninjured and regenerating cortical mammalian axons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(15):4697-707.
2009: Long Jiangang; Gao Feng; Tong Liqi; Cotman Carl W; Ames Bruce N; Liu Jiankang
Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine.
Neurochemical research 2009;34(4):755-63.
2008: Christie Lori-Ann; Saunders Richard C; Kowalska Danuta M; MacKay William A; Head Elizabeth; Cotman Carl W
Rhinal and dorsolateral prefrontal cortex lesions produce selective impairments in object and spatial learning and memory in canines.
The Journal of comparative neurology 2008;511(2):257-70.
2008: Berchtold Nicole C; Cribbs David H; Coleman Paul D; Rogers Joseph; Head Elizabeth; Kim Ronald; Beach Tom; Miller Carol; Troncoso Juan; Trojanowski John Q; Zielke H Ronald; Cotman Carl W
Gene expression changes in the course of normal brain aging are sexually dimorphic.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(40):15605-10.
2008: Tong Liqi; Balazs Robert; Soiampornkul Rungtip; Thangnipon Wipawan; Cotman Carl W
Interleukin-1 beta impairs brain derived neurotrophic factor-induced signal transduction.
Neurobiology of aging 2008;29(9):1380-93.
2008: Parachikova A; Nichol K E; Cotman C W
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition.
Neurobiology of disease 2008;30(1):121-9.
2008: Li Xuesen; Liu Zhongbo; Luo Cheng; Jia Haiqun; Sun Lijuan; Hou Bei; Shen Weili; Packer Lester; Cotman Carl W; Liu Jiankang
Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction.
Free radical biology & medicine 2008;44(7):1465-74.
2008: Siegenthaler Monica M; Berchtold Nicole C; Cotman Carl W; Keirstead Hans S
Voluntary running attenuates age-related deficits following SCI.
Experimental neurology 2008;210(1):207-16.
2008: Soiampornkul Rungtip; Tong Liqi; Thangnipon Wipawan; Balazs Robert; Cotman Carl W
Interleukin-1beta interferes with signal transduction induced by neurotrophin-3 in cortical neurons.
Brain research 2008;1188():189-97.
2008: Shen W; Liu K; Tian C; Yang L; Li X; Ren J; Packer L; Cotman C W; Liu J
R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes.
Diabetologia 2008;51(1):165-74.
2008: Siwak-Tapp Christina T; Head Elizabeth; Muggenburg Bruce A; Milgram Norton W; Cotman Carl W
Region specific neuron loss in the aged canine hippocampus is reduced by enrichment.
Neurobiology of aging 2008;29(1):39-50.
2008: Opii Wycliffe O; Joshi Gururaj; Head Elizabeth; Milgram N William; Muggenburg Bruce A; Klein Jon B; Pierce William M; Cotman Carl W; Butterfield D Allan
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease.
Neurobiology of aging 2008;29(1):51-70.
2008: Nichol Kathryn E; Poon Wayne W; Parachikova Anna I; Cribbs David H; Glabe Charles G; Cotman Carl W
Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid.
Journal of neuroinflammation 2008;5():13.
2007: Nichol Kathryn E; Parachikova Anna I; Cotman Carl W
Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse.
Behavioural brain research 2007;184(2):124-32.
2007: Parachikova A; Agadjanyan M G; Cribbs D H; Blurton-Jones M; Perreau V; Rogers J; Beach T G; Cotman C W
Inflammatory changes parallel the early stages of Alzheimer disease.
Neurobiology of aging 2007;28(12):1821-33.
2007: Parachikova A; Cotman C W
Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease.
Neurobiology of disease 2007;28(2):143-53.
2007: Cotman Carl W; Berchtold Nicole C; Christie Lori-Ann
Exercise builds brain health: key roles of growth factor cascades and inflammation.
Trends in neurosciences 2007;30(9):464-72.
2007: Siwak-Tapp Christina T; Head Elizabeth; Muggenburg Bruce A; Milgram Norton W; Cotman Carl W
Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function.
Neurobiology of learning and memory 2007;88(2):249-59.
2007: Celsi F; Svedberg M; Unger C; Cotman C W; Carrì M T; Ottersen O P; Nordberg A; Torp R
Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.
Neurobiology of disease 2007;26(2):342-52.
2007: Cotman Carl W; Berchtold Nicole C
Physical activity and the maintenance of cognition: Learning from animal models.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2007;3(2 Suppl):S30-7.
2007: Engesser-Cesar Christie; Ichiyama Ronaldo M; Nefas Amber L; Hill Mary Ann; Edgerton V Reggie; Cotman Carl W; Anderson Aileen J
Wheel running following spinal cord injury improves locomotor recovery and stimulates serotonergic fiber growth.
The European journal of neuroscience 2007;25(7):1931-9.
2007: Christie Lori-Ann; Su Joseph H; Tu Christina H; Dick Malcolm C; Zhou Jun; Cotman Carl W
Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains.
Neurobiology of disease 2007;26(1):165-73.
2007: Engesser-Cesar C; Anderson A J; Cotman C W
Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord.
Neuroscience 2007;144(3):1033-44.
2007: Rhee Seog Woo; Taylor Anne M; Cribbs David H; Cotman Carl W; Jeon Noo Li
External force-assisted cell positioning inside microfluidic devices.
Biomedical microdevices 2007;9(1):15-23.
2007: Jia Lihong; Liu Zhongbo; Sun Lijuan; Miller Sheldon S; Ames Bruce N; Cotman Carl W; Liu Jiankang
Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid.
Investigative ophthalmology & visual science 2007;48(1):339-48.
2007: Sharman Edward H; Bondy Stephen C; Sharman Kaizhi G; Lahiri Debomoy; Cotman Carl W; Perreau Victoria M
Effects of melatonin and age on gene expression in mouse CNS using microarray analysis.
Neurochemistry international 2007;50(2):336-44.
2007: Perreau V M; Bondy S C; Cotman C W; Sharman K G; Sharman E H
Melatonin treatment in old mice enables a more youthful response to LPS in the brain.
Journal of neuroimmunology 2007;182(1-2):22-31.
2007: Kayed Rakez; Head Elizabeth; Sarsoza Floyd; Saing Tommy; Cotman Carl W; Necula Mihaela; Margol Lawrence; Wu Jessica; Breydo Leonid; Thompson Jennifer L; Rasool Suhail; Gurlo Tatyana; Butler Peter; Glabe Charles G
Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers.
Molecular neurodegeneration 2007;2():18.
2006: Carrasco J; Adlard P; Cotman C; Quintana A; Penkowa M; Xu F; Van Nostrand W E; Hidalgo J
Metallothionein-I and -III expression in animal models of Alzheimer disease.
Neuroscience 2006;143(4):911-22.
2006: Chan Charles; Moore Brian E; Cotman Carl W; Okano Hideyuki; Tavares Rosemarie; Hovanesian Virginia; Pinar Halit; Johanson Conrad E; Svendsen Clive N; Stopa Edward G
Musashi1 antigen expression in human fetal germinal matrix development.
Experimental neurology 2006;201(2):515-8.
2006: Chubb Charles; Inagaki Yoshiyuki; Sheu Phillip; Cummings Brian; Wasserman Andrea; Head Elizabeth; Cotman Carl
BioVision: an application for the automated image analysis of histological sections.
Neurobiology of aging 2006;27(10):1462-76.
2006: Studzinski Christa M; Christie Lori-Ann; Araujo Joseph A; Burnham W McIntyre; Head Elizabeth; Cotman Carl W; Milgram Norton W
Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia.
Neurobiology of learning and memory 2006;86(2):197-204.
2006: Head Elizabeth; Barrett Edward G; Murphy M Paul; Das Pritam; Nistor Mihaela; Sarsoza Floyd; Glabe Charles C; Kayed Rakez; Milton Saskia; Vasilevko Vitaly; Milgram Norton W; Agadjanyan Michael G; Cribbs David H; Cotman Carl W
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta.
Vaccine 2006;24(15):2824-34.
2006: Dishman Rod K; Berthoud Hans-Rudolf; Booth Frank W; Cotman Carl W; Edgerton V Reggie; Fleshner Monika R; Gandevia Simon C; Gomez-Pinilla Fernando; Greenwood Benjamin N; Hillman Charles H; Kramer Arthur F; Levin Barry E; Moran Timothy H; Russo-Neustadt Amelia A; Salamone John D; Van Hoomissen Jacqueline D; Wade Charles E; York David A; Zigmond Michael J
Neurobiology of exercise.
Obesity (Silver Spring, Md.) 2006;14(3):345-56.
2006: Lu Po H; Masterman Donna A; Mulnard Ruth; Cotman Carl; Miller Bruce; Yaffe Kristine; Reback Erin; Porter Verna; Swerdloff Ronald; Cummings Jeffrey L
Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men.
Archives of neurology 2006;63(2):177-85.
2005: Roudebush Philip; Zicker Steven C; Cotman Carl W; Milgram Norton W; Muggenburg Bruce A; Head Elizabeth
Nutritional management of brain aging in dogs.
Journal of the American Veterinary Medical Association 2005;227(5):722-8.
2005: Taylor Anne M; Blurton-Jones Mathew; Rhee Seog Woo; Cribbs David H; Cotman Carl W; Jeon Noo Li
A microfluidic culture platform for CNS axonal injury, regeneration and transport.
Nature methods 2005;2(8):599-605.
2005: Newman Jodie; Rissman Robert A; Sarsoza Floyd; Kim Ronald C; Dick Malcolm; Bennett David A; Cotman Carl W; Rohn Troy T; Head Elizabeth
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Acta neuropathologica 2005;110(2):135-44.
2005: Cotman Carl W
The role of neurotrophins in brain aging: a perspective in honor of Regino Perez-Polo.
Neurochemical research 2005;30(6-7):877-81.
2005: Head E; Moffat K; Das P; Sarsoza F; Poon W W; Landsberg G; Cotman Carl W; Murphy M P
Beta-amyloid deposition and tau phosphorylation in clinically characterized aged cats.
Neurobiology of aging 2005;26(5):749-63.
2005: Adlard Paul A; Perreau Victoria M; Pop Viorela; Cotman Carl W
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(17):4217-21.
2005: Adlard Paul A; Perreau Victoria M; Cotman Carl W
The exercise-induced expression of BDNF within the hippocampus varies across life-span.
Neurobiology of aging 2005;26(4):511-20.
2005: Siwak Christina T; Tapp P Dwight; Head Elizabeth; Zicker Steven C; Murphey Heather L; Muggenburg Bruce A; Ikeda-Douglas Candace J; Cotman Carl W; Milgram Norton W
Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(3):461-9.
2005: Christie Lori-Ann; Studzinski Christa M; Araujo Joseph A; Leung Cleo S K; Ikeda-Douglas Candace J; Head Elizabeth; Cotman Carl W; Milgram Norton W
A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog.
Progress in neuro-psychopharmacology & biological psychiatry 2005;29(3):361-9.
2005: Cotman Carl W; Poon Wayne W; Rissman Robert A; Blurton-Jones Mathew
The role of caspase cleavage of tau in Alzheimer disease neuropathology.
Journal of neuropathology and experimental neurology 2005;64(2):104-12.
2005: Engesser-Cesar Christie; Anderson Aileen J; Basso D Michele; Edgerton V R; Cotman Carl W
Voluntary wheel running improves recovery from a moderate spinal cord injury.
Journal of neurotrauma 2005;22(1):157-71.
2005: Rhee Seog Woo; Taylor Anne M; Tu Christina H; Cribbs David H; Cotman Carl W; Jeon Noo Li
Patterned cell culture inside microfluidic devices.
Lab on a chip 2005;5(1):102-7.
2005: Milgram N W; Head E; Zicker S C; Ikeda-Douglas C J; Murphey H; Muggenburg B; Siwak C; Tapp D; Cotman C W
Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study.
Neurobiology of aging 2005;26(1):77-90.
2005: Berchtold N C; Chinn G; Chou M; Kesslak J P; Cotman C W
Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus.
Neuroscience 2005;133(3):853-61.
2005: Perreau Victoria M; Adlard Paul A; Anderson Aileen J; Cotman Carl W
Exercise-induced gene expression changes in the rat spinal cord.
Gene expression 2005;12(2):107-21.
2004: Anderson Aileen J; Robert Stephanie; Huang Wencheng; Young Wise; Cotman Carl W
Activation of complement pathways after contusion-induced spinal cord injury.
Journal of neurotrauma 2004;21(12):1831-46.
2004: Liu Jiankang; Head Elizabeth; Kuratsune Hirohiko; Cotman Carl W; Ames Bruce N
Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats.
Annals of the New York Academy of Sciences 2004;1033():117-31.
2004: Tapp P Dwight; Siwak Christina T; Gao Fu Qiang; Chiou Jr-Yuan; Black Sandra E; Head Elizabeth; Muggenburg Bruce A; Cotman Carl W; Milgram Norton W; Su Min-Ying
Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(38):8205-13.
2004: Glaser Janette; Gonzalez Rafael; Perreau Victoria M; Cotman Carl W; Keirstead Hans S
Neutralization of the chemokine CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury.
Journal of neuroscience research 2004;77(5):701-8.
2004: Tapp P Dwight; Siwak Christina T; Head Elizabeth; Cotman Carl W; Murphey Heather; Muggenburg Bruce A; Ikeda-Douglas Candace; Milgram Norton W
Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks.
Behavioural brain research 2004;153(1):199-210.
2004: Tong Liqi; Balazs Robert; Thornton Phillip L; Cotman Carl W
Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(30):6799-809.
2004: Rissman Robert A; Poon Wayne W; Blurton-Jones Mathew; Oddo Salvatore; Torp Reidun; Vitek Michael P; LaFerla Frank M; Rohn Troy T; Cotman Carl W
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation 2004;114(1):121-30.
2004: Adlard Paul A; Perreau Victoria M; Engesser-Cesar Christie; Cotman Carl W
The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise.
Neuroscience letters 2004;363(1):43-8.
2004: Milgram Norton W; Head Elizabeth; Zicker Steven C; Ikeda-Douglas Candace; Murphey Heather; Muggenberg Bruce A; Siwak Christina T; Tapp P Dwight; Lowry Stephen R; Cotman Carl W
Long-term treatment with antioxidants and a program of behavioral enrichment reduces age-dependent impairment in discrimination and reversal learning in beagle dogs.
Experimental gerontology 2004;39(5):753-65.
2004: Whitman G T; Cotman C W
Oligodendrocyte degeneration in AD.
Neurobiology of aging 2004;25(1):33-6.
2004: Johnson Julene K; Vogt Brent A; Kim Ronald; Cotman Carl W; Head Elizabeth
Isolated executive impairment and associated frontal neuropathology.
Dementia and geriatric cognitive disorders 2004;17(4):360-7.
2004: Adlard P A; Cotman C W
Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression.
Neuroscience 2004;124(4):985-92.
2003: Haier R J; Alkire M T; White N S; Uncapher M R; Head E; Lott I T; Cotman C W
Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia.
Neurology 2003;61(12):1673-9.
2003: Zhao Ming; Su Joseph; Head Elizabeth; Cotman Carl W
Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease.
Neurobiology of disease 2003;14(3):391-403.
2003: Nippak Pria M D; Chan Alan D F; Campbell Zachariah; Muggenburg Bruce; Head Elizabeth; Ikeda-Douglas Candace J; Murphey Heather; Cotman Carl W; Milgram Norton W
Response latency in Canis familiaris: mental ability or mental strategy?
Behavioral neuroscience 2003;117(5):1066-75.
2003: Head E; Lott I T; Hof P R; Bouras C; Su J H; Kim R; Haier R; Cotman C W
Parallel compensatory and pathological events associated with tau pathology in middle aged individuals with Down syndrome.
Journal of neuropathology and experimental neurology 2003;62(9):917-26.
2003: Bi Xiaoning; Head Elizabeth; Cotman Carl W; Lynch Gary
Spatial patterns of mammalian brain aging: distribution of cathepsin D-immunoreactive cell bodies and dystrophic dendrites in aging dogs resembles that in Alzheimer's disease.
The Journal of comparative neurology 2003;464(3):371-81.
2003: Siwak Christina T; Tapp P Dwight; Zicker Steven C; Murphey Heather L; Muggenburg Bruce A; Head Elizabeth; Cotman Carl W; Milgram Norton W
Locomotor activity rhythms in dogs vary with age and cognitive status.
Behavioral neuroscience 2003;117(4):813-24.
2003: Ramsden Martin; Berchtold Nicole C; Patrick Kesslak J; Cotman Carl W; Pike Christian J
Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion.
Brain research 2003;971(2):239-44.
2003: Su Joseph H; Anderson Aileen J; Cribbs David H; Tu Christina; Tong Liqi; Kesslack Patrick; Cotman Carl W
Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death.
Neurobiology of disease 2003;12(3):182-93.
2003: Kayed Rakez; Head Elizabeth; Thompson Jennifer L; McIntire Theresa M; Milton Saskia C; Cotman Carl W; Glabe Charles G
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.
Science (New York, N.Y.) 2003;300(5618):486-9.
2003: Cribbs David H; Ghochikyan Anahit; Vasilevko Vitaly; Tran Mike; Petrushina Irina; Sadzikava Nadya; Babikyan Davit; Kesslak Patrick; Kieber-Emmons Thomas; Cotman Carl W; Agadjanyan Michael G
Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid.
International immunology 2003;15(4):505-14.
2003: Zhao Ming; Cribbs David H; Anderson Aileen J; Cummings Brian J; Su Joseph H; Wasserman Andrea J; Cotman Carl W
The induction of the TNFalpha death domain signaling pathway in Alzheimer's disease brain.
Neurochemical research 2003;28(2):307-18.
2003: Tapp P Dwight; Siwak Christina T; Estrada Jimena; Head Elizabeth; Muggenburg Bruce A; Cotman Carl W; Milgram Norton W
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging.
Learning & memory (Cold Spring Harbor, N.Y.) 2003;10(1):64-73.
2003: Torp R; Ottersen O P; Cotman C W; Head E
Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for beta-amyloid precursor protein processing.
Neuroscience 2003;120(2):291-300.
2003: Garcia C; Chen M J; Garza A A; Cotman C W; Russo-Neustadt A
The influence of specific noradrenergic and serotonergic lesions on the expression of hippocampal brain-derived neurotrophic factor transcripts following voluntary physical activity.
Neuroscience 2003;119(3):721-32.
2002: Rohn Troy T; Rissman Robert A; Davis Michael C; Kim Young Eun; Cotman Carl W; Head Elizabeth
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain.
Neurobiology of disease 2002;11(2):341-54.
2002: Aliev Gjumrakch; Seyidova Dilara; Neal Maxwell L; Shi Jiong; Lamb Bruce T; Siedlak Sandra L; Vinters Harry V; Head Elizabeth; Perry George; Lamanna Joseph C; Friedland Robert P; Cotman Carl W
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice.
Annals of the New York Academy of Sciences 2002;977():45-64.
2002: Milgram Norton W; Head E; Muggenburg B; Holowachuk D; Murphey H; Estrada J; Ikeda-Douglas C J; Zicker S C; Cotman C W
Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy.
Neuroscience and biobehavioral reviews 2002;26(6):679-95.
2002: Cotman Carl W; Head Elizabeth; Muggenburg Bruce A; Zicker S; Milgram Norton W
Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction.
Neurobiology of aging 2002;23(5):809-18.
2002: Milgram N W; Zicker S C; Head E; Muggenburg B A; Murphey H; Ikeda-Douglas C J; Cotman C W
Dietary enrichment counteracts age-associated cognitive dysfunction in canines.
Neurobiology of aging 2002;23(5):737-45.
2002: Head Elizabeth; Lott I T; Cribbs David H; Cotman Carl W; Rohn Troy T
Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome.
Neuroscience letters 2002;330(1):99-103.
2002: Albert Katherine A; Hemmings Hugh C; Adamo Anna I B; Potkin Steven G; Akbarian Schahram; Sandman Curt A; Cotman Carl W; Bunney William E; Greengard Paul
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.
Archives of general psychiatry 2002;59(8):705-12.
2002: Head E; Liu J; Hagen T M; Muggenburg B A; Milgram N W; Ames B N; Cotman C W
Oxidative damage increases with age in a canine model of human brain aging.
Journal of neurochemistry 2002;82(2):375-81.
2002: Fillit Howard M; Butler Robert N; O'Connell Alan W; Albert Marilyn S; Birren James E; Cotman Carl W; Greenough William T; Gold Paul E; Kramer Arthur F; Kuller Lewis H; Perls Thomas T; Sahagan Barbara G; Tully Tim
Achieving and maintaining cognitive vitality with aging.
Mayo Clinic proceedings. Mayo Clinic 2002;77(7):681-96.
2002: Su Joseph H; Kesslak J Patrick; Head Elizabeth; Cotman Carl W
Caspase-cleaved amyloid precursor protein and activated caspase-3 are co-localized in the granules of granulovacuolar degeneration in Alzheimer's disease and Down's syndrome brain.
Acta neuropathologica 2002;104(1):1-6.
2002: Berchtold Nicole C; Kesslak J Patrick; Cotman Carl W
Hippocampal brain-derived neurotrophic factor gene regulation by exercise and the medial septum.
Journal of neuroscience research 2002;68(5):511-21.
2002: Cotman Carl W; Berchtold Nicole C
Exercise: a behavioral intervention to enhance brain health and plasticity.
Trends in neurosciences 2002;25(6):295-301.
2002: Chan Alan D F; Nippak Pria M D; Murphey Heather; Ikeda-Douglas Candace J; Muggenburg Bruce; Head Elizabeth; Cotman Carl W; Milgram Norton W
Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility.
Behavioral neuroscience 2002;116(3):443-54.
2002: Cotman Carl W; Engesser-Cesar Christie
Exercise enhances and protects brain function.
Exercise and sport sciences reviews 2002;30(2):75-9.
2002: SantaCruz K S; Tasaki C S; Kim R C; Cotman C W
Brainstem and cortical Lewy bodies in patients presenting clinically with Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2002;4(1):11-7.
2002: Liu Jiankang; Head Elizabeth; Gharib Afshin M; Yuan Wenjun; Ingersoll Russell T; Hagen Tory M; Cotman Carl W; Ames Bruce N
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2356-61.
2002: Soreghan Brian; Pike Christian; Kayed Rakez; Tian Wenquiang; Milton Saskia; Cotman Carl; Glabe Charles G
The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties.
Neuromolecular medicine 2002;1(1):81-94.
2001: Berchtold N C; Kesslak J P; Pike C J; Adlard P A; Cotman C W
Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus.
The European journal of neuroscience 2001;14(12):1992-2002.
2001: Tong L; Shen H; Perreau V M; Balazs R; Cotman C W
Effects of exercise on gene-expression profile in the rat hippocampus.
Neurobiology of disease 2001;8(6):1046-56.
2001: Rohn T T; Head E; Nesse W H; Cotman C W; Cribbs D H
Activation of caspase-8 in the Alzheimer's disease brain.
Neurobiology of disease 2001;8(6):1006-16.
2001: Head E; Garzon-Rodriguez W; Johnson J K; Lott I T; Cotman C W; Glabe C
Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome.
Neurobiology of disease 2001;8(5):792-806.
2001: Stoltzner S E; Berchtold N C; Cotman C W; Pike C J
Estrogen regulates bcl-x expression in rat hippocampus.
Neuroreport 2001;12(13):2797-800.
2001: Nichol K E; Kim R; Cotman C W
Bcl-2 family protein behavior in frontotemporal dementia implies vascular involvement.
Neurology 2001;56(11 Suppl 4):S35-40.
2001: Brewer G J; Espinosa J; McIlhaney M P; Pencek T P; Kesslak J P; Cotman C; Viel J; McManus D C
Culture and regeneration of human neurons after brain surgery.
Journal of neuroscience methods 2001;107(1-2):15-23.
2001: Tong L; Thornton P L; Balazs R; Cotman C W
Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised.
The Journal of biological chemistry 2001;276(20):17301-6.
2001: Su J H; Zhao M; Anderson A J; Srinivasan A; Cotman C W
Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.
Brain research 2001;898(2):350-7.
2001: Head E; Azizeh B Y; Lott I T; Tenner A J; Cotman C W; Cribbs D H
Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome.
Neurobiology of disease 2001;8(2):252-65.
2001: Rohn T T; Wong S M; Cotman C W; Cribbs D H
15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis.
Neuroreport 2001;12(4):839-43.
2001: Martin J A; Craft D K; Su J H; Kim R C; Cotman C W
Astrocytes degenerate in frontotemporal dementia: possible relation to hypoperfusion.
Neurobiology of aging 2001;22(2):195-207.
2001: Rohn T T; Head E; Su J H; Anderson A J; Bahr B A; Cotman C W; Cribbs D H
Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease.
The American journal of pathology 2001;158(1):189-98.
2001: Shen H; Tong L; Balazs R; Cotman C W
Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus.
Neuroscience 2001;107(2):219-29.
2000: Dick M B; Hsieh S; Dick-Muehlke C; Davis D S; Cotman C W
The variability of practice hypothesis in motor learning: does it apply to Alzheimer's disease?
Brain and cognition 2000;44(3):470-89.
2000: Torp R; Head E; Cotman C W
Ultrastructural analyses of beta-amyloid in the aged dog brain: neuronal beta-amyloid is localized to the plasma membrane.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):801-10.
2000: Head E; Thornton P L; Tong L; Cotman C W
Initiation and propagation of molecular cascades in human brain aging: insight from the canine model to promote successful aging.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):777-86.
2000: Callahan H; Ikeda-Douglas C; Head E; Cotman C W; Milgram N W
Development of a protocol for studying object recognition memory in the dog.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):693-707.
2000: Head E; Cotman C W; Milgram N W
Canine cognition, aging and neuropathology. Introduction.
Progress in neuro-psychopharmacology & biological psychiatry 2000;24(5):671-3.
2000: Rohn T T; Ivins K J; Bahr B A; Cotman C W; Cribbs D H
A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis.
Journal of neurochemistry 2000;74(6):2331-42.
2000: Ulas J; Satou T; Ivins K J; Kesslak J P; Cotman C W; Balázs R
Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures.
Glia 2000;30(4):352-61.
2000: Kim T S; Park M; Nepomuceno R R; Palmarini G; Winokur S; Cotman C A; Bengtsson U; Tenner A J
Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P).
Molecular immunology 2000;37(7):377-89.
2000: Cribbs D H; Azizeh B Y; Cotman C W; LaFerla F M
Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's A beta peptide.
Biochemistry 2000;39(20):5988-94.
2000: Azizeh B Y; Head E; Ibrahim M A; Torp R; Tenner A J; Kim R C; Lott I T; Cotman C W
Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs.
Experimental neurology 2000;163(1):111-22.
2000: Su J H; Nichol K E; Sitch T; Sheu P; Chubb C; Miller B L; Tomaselli K J; Kim R C; Cotman C W
DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia.
Experimental neurology 2000;163(1):9-19.
2000: Mulnard R A; Cotman C W; Kawas C; van Dyck C H; Sano M; Doody R; Koss E; Pfeiffer E; Jin S; Gamst A; Grundman M; Thomas R; Thal L J
Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study.
JAMA : the journal of the American Medical Association 2000;283(8):1007-15.
2000: Adams B; Chan A; Callahan H; Siwak C; Tapp D; Ikeda-Douglas C; Atkinson P; Head E; Cotman C W; Milgram N W
Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog.
Behavioural brain research 2000;108(1):47-56.
2000: Head E; McCleary R; Hahn F F; Milgram N W; Cotman C W
Region-specific age at onset of beta-amyloid in dogs.
Neurobiology of aging 2000;21(1):89-96.
2000: Cotman C W; Anderson A J
The brain's microenvironment, early functional loss, and the conversion to Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;924():112-6.
2000: Russo-Neustadt A A; Beard R C; Huang Y M; Cotman C W
Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus.
Neuroscience 2000;101(2):305-12.
2000: Torp R; Head E; Milgram N W; Hahn F; Ottersen O P; Cotman C W
Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains.
Neuroscience 2000;96(3):495-506.
1999: Russo-Neustadt A; Beard R C; Cotman C W
Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(5):679-82.
1999: Ivins K J; Thornton P L; Rohn T T; Cotman C W
Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.
Neurobiology of disease 1999;6(5):440-9.
1999: Johnson J K; Head E; Kim R; Starr A; Cotman C W
Clinical and pathological evidence for a frontal variant of Alzheimer disease.
Archives of neurology 1999;56(10):1233-9.
1999: Davis J; Cribbs D H; Cotman C W; Van Nostrand W E
Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(3):157-64.
1999: Deng G; Su J H; Ivins K J; Van Houten B; Cotman C W
Bcl-2 facilitates recovery from DNA damage after oxidative stress.
Experimental neurology 1999;159(1):309-18.
1999: Kim D; Su J; Cotman C W
Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment.
Brain research 1999;839(2):253-62.
1999: Berchtold N C; Oliff H S; Isackson P; Cotman C W
Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript.
Brain research. Molecular brain research 1999;71(1):11-22.
1999: Fonseca M I; Head E; Velazquez P; Cotman C W; Tenner A J
The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age.
Experimental neurology 1999;157(2):277-88.
1999: Leissring M A; Paul B A; Parker I; Cotman C W; LaFerla F M
Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes.
Journal of neurochemistry 1999;72(3):1061-8.
1999: Milgram N W; Adams B; Callahan H; Head E; Mackay B; Thirlwell C; Cotman C W
Landmark discrimination learning in the dog.
Learning & memory (Cold Spring Harbor, N.Y.) 1999;6(1):54-61.
1999: Ivins K J; Ivins J K; Sharp J P; Cotman C W
Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid.
The Journal of biological chemistry 1999;274(4):2107-12.
1998: Johnson J K; Cotman C W; Tasaki C S; Shaw G L
Enhancement of spatial-temporal reasoning after a Mozart listening condition in Alzheimer's disease: a case study.
Neurological research 1998;20(8):666-72.
1998: Ivins K J; Bui E T; Cotman C W
Beta-amyloid induces local neurite degeneration in cultured hippocampal neurons: evidence for neuritic apoptosis.
Neurobiology of disease 1998;5(5):365-78.
1998: Su J H; Cummings B J; Cotman C W
Plaque biogenesis in brain aging and Alzheimer's disease. II. Progressive transformation and developmental sequence of dystrophic neurites.
Acta neuropathologica 1998;96(5):463-71.
1998: Russo-Neustadt A; Zomorodian T J; Cotman C W
Preserved cerebellar tyrosine hydroxylase-immunoreactive neuronal fibers in a behaviorally aggressive subgroup of Alzheimer's disease patients.
Neuroscience 1998;87(1):55-61.
1998: Torp R; Su J H; Deng G; Cotman C W
GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro.
Neurobiology of disease 1998;5(4):245-52.
1998: Oliff H S; Berchtold N C; Isackson P; Cotman C W
Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus.
Brain research. Molecular brain research 1998;61(1-2):147-53.
1998: Miller B L; Cummings J; Mishkin F; Boone K; Prince F; Ponton M; Cotman C
Emergence of artistic talent in frontotemporal dementia.
Neurology 1998;51(4):978-82.
1998: Su M Y; Head E; Brooks W M; Wang Z; Muggenburg B A; Adam G E; Sutherland R; Cotman C W; Nalcioglu O
Magnetic resonance imaging of anatomic and vascular characteristics in a canine model of human aging.
Neurobiology of aging 1998;19(5):479-85.
1998: Head E; Callahan H; Muggenburg B A; Cotman C W; Milgram N W
Visual-discrimination learning ability and beta-amyloid accumulation in the dog.
Neurobiology of aging 1998;19(5):415-25.
1998: Kesslak J P; So V; Choi J; Cotman C W; Gomez-Pinilla F
Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance?
Behavioral neuroscience 1998;112(4):1012-9.
1998: Eckert A; Cotman C W; Zerfass R; Hennerici M; Müller W E
Enhanced vulnerability to apoptotic cell death in sporadic Alzheimer's disease.
Neuroreport 1998;9(11):2443-6.
1998: Stenger D A; Hickman J J; Bateman K E; Ravenscroft M S; Ma W; Pancrazio J J; Shaffer K; Schaffner A E; Cribbs D H; Cotman C W
Microlithographic determination of axonal/dendritic polarity in cultured hippocampal neurons.
Journal of neuroscience methods 1998;82(2):167-73.
1998: Cotman C W; Hailer N P; Pfister K K; Soltesz I; Schachner M
Cell adhesion molecules in neural plasticity and pathology: similar mechanisms, distinct organizations?
Progress in neurobiology 1998;55(6):659-69.
1998: Sheetz M P; Pfister K K; Bulinski J C; Cotman C W
Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration.
Progress in neurobiology 1998;55(6):577-94.
1998: Johnson J K; McCleary R; Oshita M H; Cotman C W
Initiation and propagation stages of beta-amyloid are associated with distinctive apolipoprotein E, age, and gender profiles.
Brain research 1998;798(1-2):18-24.
1998: Azizeh B Y; Cribbs D H; Kreng V M; Cotman C W
Cross-linking of NCAM receptors on neurons induces programmed cell death.
Brain research 1998;796(1-2):20-6.
1998: Balázs R; Miller S; Chun Y; O'Toole J; Cotman C W
Metabotropic glutamate receptor agonists potentiate cyclic AMP formation induced by forskolin or beta-adrenergic receptor activation in cerebral cortical astrocytes in culture.
Journal of neurochemistry 1998;70(6):2446-58.
1998: Berchtold N C; Cotman C W
Evolution in the conceptualization of dementia and Alzheimer's disease: Greco-Roman period to the 1960s.
Neurobiology of aging 1998;19(3):173-89.
1998: Balázs R; Miller S; Chun Y; Cotman C W
Receptor-coupled phospholipase C and adenylyl cyclase function with different calcium pools in astrocytes.
Neuroreport 1998;9(7):1397-401.
1998: Ibrahim M A; Emerson J F; Cotman C W
Magnetic resonance imaging relaxation times and gadolinium-DTPA relaxivity values in human cerebrospinal fluid.
Investigative radiology 1998;33(3):153-62.
1998: Cotman C W
Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease.
Neurobiology of aging 1998;19(1 Suppl):S29-32.
1998: Eckert A; Cotman C W; Zerfass R; Hennerici M; Müller W E
Lymphocytes as cell model to study apoptosis in Alzheimer's disease: vulnerability to programmed cell death appears to be altered.
Journal of neural transmission. Supplementum 1998;54():259-67.
1997: Su J H; Deng G; Cotman C W
Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
Brain research 1997;774(1-2):193-9.
1997: Satou T; Cummings B J; Head E; Nielson K A; Hahn F F; Milgram N W; Velazquez P; Cribbs D H; Tenner A J; Cotman C W
The progression of beta-amyloid deposition in the frontal cortex of the aged canine.
Brain research 1997;774(1-2):35-43.
1997: Head E; Callahan H; Cummings B J; Cotman C W; Ruehl W W; Muggenberg B A; Milgram N W
Open field activity and human interaction as a function of age and breed in dogs.
Physiology & behavior 1997;62(5):963-71.
1997: Pike C J; Ramezan-Arab N; Cotman C W
Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants.
Journal of neurochemistry 1997;69(4):1601-11.
1997: Major D E; Kesslak J P; Cotman C W; Finch C E; Day J R
Life-long dietary restriction attenuates age-related increases in hippocampal glial fibrillary acidic protein mRNA.
Neurobiology of aging 1997;18(5):523-6.
1997: de Figueiredo R J; Oten R; Su J; Cotman C W
Amyloid deposition in cerebrovascular angiopathy.
Annals of the New York Academy of Sciences 1997;826():463-71.
1997: Ulas J; Cotman C W
Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain.
Neuroscience 1997;79(4):973-82.
1997: Russo-Neustadt A; Cotman C W
Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5573-80.
1997: Donovan F M; Pike C J; Cotman C W; Cunningham D D
Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5316-26.
1997: Balázs R; Miller S; Romano C; de Vries A; Chun Y; Cotman C W
Metabotropic glutamate receptor mGluR5 in astrocytes: pharmacological properties and agonist regulation.
Journal of neurochemistry 1997;69(1):151-63.
1997: Cotman C W
The beta-amyloid peptide, peptide self-assembly, and the emergence of biological activities. A new principle in peptide function and the induction of neuropathology.
Annals of the New York Academy of Sciences 1997;814():1-16.
1997: Sano M; Ernesto C; Thomas R G; Klauber M R; Schafer K; Grundman M; Woodbury P; Growdon J; Cotman C W; Pfeiffer E; Schneider L S; Thal L J
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.
The New England journal of medicine 1997;336(17):1216-22.
1997: Cribbs D H; Pike C J; Weinstein S L; Velazquez P; Cotman C W
All-D-enantiomers of beta-amyloid exhibit similar biological properties to all-L-beta-amyloids.
The Journal of biological chemistry 1997;272(11):7431-6.
1997: Su J H; Deng G; Cotman C W
Bax protein expression is increased in Alzheimer's brain: correlations with DNA damage, Bcl-2 expression, and brain pathology.
Journal of neuropathology and experimental neurology 1997;56(1):86-93.
1997: Gómez-Pinilla F; Miller S; Choi J; Cotman C W
Heparan sulfate potentiates the autocrine action of basic fibroblast growth factor in astrocytes: an in vivo and in vitro study.
Neuroscience 1997;76(1):137-45.
1997: Su J H; Deng G; Cotman C W
Transneuronal degeneration in the spread of Alzheimer's disease pathology: immunohistochemical evidence for the transmission of tau hyperphosphorylation.
Neurobiology of disease 1997;4(5):365-75.
1996: Cummings B J; Pike C J; Shankle R; Cotman C W
Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease.
Neurobiology of aging 1996;17(6):921-33.
1996: Nielson K A; Cummings B J; Cotman C W
Constructional apraxia in Alzheimer's disease correlates with neuritic neuropathology in occipital cortex.
Brain research 1996;741(1-2):284-93.
1996: Su J H; Cummings B J; Cotman C W
Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments.
Brain research 1996;739(1-2):79-87.
1996: Deng G; Pike C J; Cotman C W
Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells.
FEBS letters 1996;397(1):50-4.
1996: Cribbs D H; Kreng V M; Anderson A J; Cotman C W
Cross-linking of concanavalin A receptors on cortical neurons induces programmed cell death.
Neuroscience 1996;75(1):173-85.
1996: Cotman C W; Su J H
Mechanisms of neuronal death in Alzheimer's disease.
Brain pathology (Zurich, Switzerland) 1996;6(4):493-506.
1996: Pike C J; Balázs R; Cotman C W
Attenuation of beta-amyloid neurotoxicity in vitro by potassium-induced depolarization.
Journal of neurochemistry 1996;67(4):1774-7.
1996: Miller S; Sehati N; Romano C; Cotman C W
Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5.
Journal of neurochemistry 1996;67(4):1435-47.
1996: Deng G; Su J H; Cotman C W
Gene expression of Alzheimer-associated presenilin-2 in the frontal cortex of Alzheimer and aged control brain.
FEBS letters 1996;394(1):17-20.
1996: Cotman C W; Tenner A J; Cummings B J
beta-Amyloid converts an acute phase injury response to chronic injury responses.
Neurobiology of aging 1996;17(5):723-31.
1996: Nielson K A; Nolan J H; Berchtold N C; Sandman C A; Mulnard R A; Cotman C W
Apolipoprotein-E genotyping of diabetic dementia patients: is diabetes rare in Alzheimer's disease?
Journal of the American Geriatrics Society 1996;44(8):897-904.
1996: Ulas J; Cotman C W
Dopaminergic denervation of striatum results in elevated expression of NR2A subunit.
Neuroreport 1996;7(11):1789-93.
1996: Cribbs D H; Chen L S; Cotman C W; LaFerla F M
Injury induces presenilin-1 gene expression in mouse brain.
Neuroreport 1996;7(11):1773-6.
1996: Neeper S A; Gómez-Pinilla F; Choi J; Cotman C W
Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain.
Brain research 1996;726(1-2):49-56.
1996: Cummings B J; Satou T; Head E; Milgram N W; Cole G M; Savage M J; Podlisny M B; Selkoe D J; Siman R; Greenberg B D; Cotman C W
Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs.
Neurobiology of aging 1996;17(4):653-9.
1996: Cummings B J; Head E; Afagh A J; Milgram N W; Cotman C W
Beta-amyloid accumulation correlates with cognitive dysfunction in the aged canine.
Neurobiology of learning and memory 1996;66(1):11-23.
1996: Pike C J; Ramezan-Arab N; Miller S; Cotman C W
beta-Amyloid increases enzyme activity and protein levels of glutamine synthetase in cultured astrocytes.
Experimental neurology 1996;139(1):167-71.
1996: Pike C J; Vaughan P J; Cunningham D D; Cotman C W
Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro.
Journal of neurochemistry 1996;66(4):1374-82.
1996: Dick M B; Shankle R W; Beth R E; Dick-Muehlke C; Cotman C W; Kean M L
Acquisition and long-term retention of a gross motor skill in Alzheimer's disease patients under constant and varied practice conditions.
The journals of gerontology. Series B, Psychological sciences and social sciences 1996;51(2):P103-11.
1996: Anderson A J; Su J H; Cotman C W
DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(5):1710-9.
1996: Cummings B J; Head E; Ruehl W; Milgram N W; Cotman C W
The canine as an animal model of human aging and dementia.
Neurobiology of aging 1996;17(2):259-68.
1996: Afagh A; Cummings B J; Cribbs D H; Cotman C W; Tenner A J
Localization and cell association of C1q in Alzheimer's disease brain.
Experimental neurology 1996;138(1):22-32.
1996: Su J H; Satou T; Anderson A J; Cotman C W
Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease.
Neuroreport 1996;7(2):437-40.
1995: Dick M B; Nielson K A; Beth R E; Shankle W R; Cotman C W
Acquisition and long-term retention of a fine motor skill in Alzheimer's disease.
Brain and cognition 1995;29(3):294-306.
1995: Cummings B J; Cotman C W
Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity.
Lancet 1995;346(8989):1524-8.
1995: Woods A G; Cribbs D H; Whittemore E R; Cotman C W
Heparan sulfate and chondroitin sulfate glycosaminoglycan attenuate beta-amyloid(25-35) induced neurodegeneration in cultured hippocampal neurons.
Brain research 1995;697(1-2):53-62.
1995: Satou T; Cummings B J; Cotman C W
Immunoreactivity for Bcl-2 protein within neurons in the Alzheimer's disease brain increases with disease severity.
Brain research 1995;697(1-2):35-43.
1995: Loo D T; Althoen M C; Cotman C W
Differentiation of serum-free mouse embryo cells into astrocytes is accompanied by induction of glutamine synthetase activity.
Journal of neuroscience research 1995;42(2):184-91.
1995: Head E; Mehta R; Hartley J; Kameka M; Cummings B J; Cotman C W; Ruehl W W; Milgram N W
Spatial learning and memory as a function of age in the dog.
Behavioral neuroscience 1995;109(5):851-8.
1995: Pike C J; Overman M J; Cotman C W
Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro.
The Journal of biological chemistry 1995;270(41):23895-8.
1995: Anderson A J; Pike C J; Cotman C W
Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.
Journal of neurochemistry 1995;65(4):1487-98.
1995: Miller S; Romano C; Cotman C W
Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(9):6103-9.
1995: Whittemore E R; Loo D T; Watt J A; Cotman C W
A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture.
Neuroscience 1995;67(4):921-32.
1995: Davis-Salinas J; Saporito-Irwin S M; Cotman C W; Van Nostrand W E
Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells.
Journal of neurochemistry 1995;65(2):931-4.
1995: Korotzer A R; Watt J; Cribbs D; Tenner A J; Burdick D; Glabe C; Cotman C W
Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia.
Experimental neurology 1995;134(2):214-21.
1995: Choi B H; Kim R C; Vaughan P J; Lau A; Van Nostrand W E; Cotman C W; Cunningham D D
Decreases in protease nexins in Alzheimer's disease brain.
Neurobiology of aging 1995;16(4):557-62.
1995: Vaughan P J; Pike C J; Cotman C W; Cunningham D D
Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 2):5389-401.
1995: deFigueiredo R J; Shankle W R; Maccato A; Dick M B; Mundkur P; Mena I; Cotman C W
Neural-network-based classification of cognitively normal, demented, Alzheimer disease and vascular dementia from single photon emission with computed tomography image data from brain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5530-4.
1995: Gómez-Pinilla F; van der Wal E A; Cotman C W
Possible coordinated gene expressions for FGF receptor, FGF-5, and FGF-2 following seizures.
Experimental neurology 1995;133(2):164-74.
1995: Araujo D M; Cotman C W
Differential effects of interleukin-1 beta and interleukin-2 on glia and hippocampal neurons in culture.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1995;13(3-4):201-12.
1995: Miller S; Kesslak J P; Romano C; Cotman C W
Roles of metabotropic glutamate receptors in brain plasticity and pathology.
Annals of the New York Academy of Sciences 1995;757():460-74.
1995: Pike C J; Cummings B J; Cotman C W
Early association of reactive astrocytes with senile plaques in Alzheimer's disease.
Experimental neurology 1995;132(2):172-9.
1995: Gómez-Pinilla F; Vu L; Cotman C W
Regulation of astrocyte proliferation by FGF-2 and heparan sulfate in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 1):2021-9.
1995: Kesslak J P; Yuan D; Neeper S; Cotman C W
Vulnerability of the hippocampus to kainate excitotoxicity in the aged, mature and young adult rat.
Neuroscience letters 1995;188(2):117-20.
1995: Defigueiredo R J; Cummings B J; Mundkur P Y; Cotman C W
Color image analysis in neuroanatomical research: application to senile plaque subtype quantification in Alzheimer's disease.
Neurobiology of aging 1995;16(2):211-23.
1995: Pike C J; Cotman C W
Calretinin-immunoreactive neurons are resistant to beta-amyloid toxicity in vitro.
Brain research 1995;671(2):293-8.
1995: Cotman C W; Anderson A J
A potential role for apoptosis in neurodegeneration and Alzheimer's disease.
Molecular neurobiology 1995;10(1):19-45.
1995: Neeper S A; Gómez-Pinilla F; Choi J; Cotman C
Exercise and brain neurotrophins.
Nature 1995;373(6510):109.
1995: Pike C J; Walencewicz-Wasserman A J; Kosmoski J; Cribbs D H; Glabe C G; Cotman C W
Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity.
Journal of neurochemistry 1995;64(1):253-65.
1995: Korotzer A R; Whittemore E R; Cotman C W
Differential regulation by beta-amyloid peptides of intracellular free Ca2+ concentration in cultured rat microglia.
European journal of pharmacology 1995;288(2):125-30.
1995: Shankle W R; Nielson K A; Cotman C W
Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients.
Alzheimer disease and associated disorders 1995;9(4):233-7.
1995: Ruehl W W; Bruyette D S; DePaoli A; Cotman C W; Head E; Milgram N W; Cummings B J
Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy.
Progress in brain research 1995;106():217-25.
1994: Cotman C W; Whittemore E R; Watt J A; Anderson A J; Loo D T
Possible role of apoptosis in Alzheimer's disease.
Annals of the New York Academy of Sciences 1994;747():36-49.
1994: Vaughan P J; Su J; Cotman C W; Cunningham D D
Protease nexin-1, a potent thrombin inhibitor, is reduced around cerebral blood vessels in Alzheimer's disease.
Brain research 1994;668(1-2):160-70.
1994: Su J H; Anderson A J; Cummings B J; Cotman C W
Immunohistochemical evidence for apoptosis in Alzheimer's disease.
Neuroreport 1994;5(18):2529-33.
1994: Ulas J; Weihmuller F B; Brunner L C; Joyce J N; Marshall J F; Cotman C W
Selective increase of NMDA-sensitive glutamate binding in the striatum of Parkinson's disease, Alzheimer's disease, and mixed Parkinson's disease/Alzheimer's disease patients: an autoradiographic study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(11 Pt 1):6317-24.
1994: Pike C J; Cummings B J; Monzavi R; Cotman C W
Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease.
Neuroscience 1994;63(2):517-31.
1994: Su J H; Cummings B J; Cotman C W
Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites.
Neuroreport 1994;5(17):2358-62.
1994: Miller S; Bridges R J; Chamberlin A R; Cotman C W
Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes.
European journal of pharmacology 1994;269(2):235-41.
1994: Watt J A; Pike C J; Walencewicz-Wasserman A J; Cotman C W
Ultrastructural analysis of beta-amyloid-induced apoptosis in cultured hippocampal neurons.
Brain research 1994;661(1-2):147-56.
1994: Smyth M D; Cribbs D H; Tenner A J; Shankle W R; Dick M; Kesslak J P; Cotman C W
Decreased levels of C1q in cerebrospinal fluid of living Alzheimer patients correlate with disease state.
Neurobiology of aging 1994;15(5):609-14.
1994: Gómez-Pinilla F; Lee J W; Cotman C W
Distribution of basic fibroblast growth factor in the developing rat brain.
Neuroscience 1994;61(4):911-23.
1994: Loo D T; Althoen M C; Cotman C W
Down regulation of nestin by TGF-beta or serum in SFME cells accompanies differentiation into astrocytes.
Neuroreport 1994;5(13):1585-8.
1994: Whittemore E R; Loo D T; Cotman C W
Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons.
Neuroreport 1994;5(12):1485-8.
1994: Bridges R J; Lovering F E; Koch H; Cotman C W; Chamberlin A R
A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate.
Neuroscience letters 1994;174(2):193-7.
1994: Jiang H; Burdick D; Glabe C G; Cotman C W; Tenner A J
beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(10):5050-9.
1994: Van Der Wal E A; Gómez-Pinilla F; Cotman C W
Seizure-associated induction of basic fibroblast growth factor and its receptor in the rat brain.
Neuroscience 1994;60(2):311-23.
1994: Smyth M D; Kesslak J P; Cummings B J; Cotman C W
Analysis of brain injury following intrahippocampal administration of beta-amyloid in streptozotocin-treated rats.
Neurobiology of aging 1994;15(2):153-9.
1994: Anderson A J; Cummings B J; Cotman C W
Increased immunoreactivity for Jun- and Fos-related proteins in Alzheimer's disease: association with pathology.
Experimental neurology 1994;125(2):286-95.
1994: Su J H; Cummings B J; Cotman C W
Subpopulations of dystrophic neurites [correction of neuritis] in Alzheimer's brain with distinct immunocytochemical and argentophilic characteristics.
Brain research 1994;637(1-2):37-44.
1994: Weiss J H; Pike C J; Cotman C W
Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.
Journal of neurochemistry 1994;62(1):372-5.
1994: Cotman C W
Report of Alzheimer's disease Working Group A.
Neurobiology of aging 1994;15 Suppl 2():S17-22.
1993: Cummings B J; Su J H; Cotman C W
Neuritic involvement within bFGF immunopositive plaques of Alzheimer's disease.
Experimental neurology 1993;124(2):315-25.
1993: Stenger D A; Pike C J; Hickman J J; Cotman C W
Surface determinants of neuronal survival and growth on self-assembled monolayers in culture.
Brain research 1993;630(1-2):136-47.
1993: Cummings B J; Su J H; Cotman C W; White R; Russell M J
Beta-amyloid accumulation in aged canine brain: a model of early plaque formation in Alzheimer's disease.
Neurobiology of aging 1993;14(6):547-60.
1993: Kahle J S; Cotman C W
Synaptic reorganization in the hippocampus: an electrophysiological analysis.
Annals of the New York Academy of Sciences 1993;702():61-74.
1993: Berkman L F; Seeman T E; Albert M; Blazer D; Kahn R; Mohs R; Finch C; Schneider E; Cotman C; McClearn G
High, usual and impaired functioning in community-dwelling older men and women: findings from the MacArthur Foundation Research Network on Successful Aging.
Journal of clinical epidemiology 1993;46(10):1129-40.
1993: Wagner S L; Van Nostrand W E; Lau A L; Farrow J S; Suzuki M; Bartus R T; Schuppek R; Nguyen A; Cotman C W; Cunningham D D
Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates.
Brain research 1993;626(1-2):90-8.
1993: Su J H; Cummings B J; Cotman C W
Identification and distribution of axonal dystrophic neurites in Alzheimer's disease.
Brain research 1993;625(2):228-37.
1993: Korotzer A R; Pike C J; Cotman C W
beta-Amyloid peptides induce degeneration of cultured rat microglia.
Brain research 1993;624(1-2):121-5.
1993: Loo D T; Copani A; Pike C J; Whittemore E R; Walencewicz A J; Cotman C W
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):7951-5.
1993: Pike C J; Cotman C W
Cultured GABA-immunoreactive neurons are resistant to toxicity induced by beta-amyloid.
Neuroscience 1993;56(2):269-74.
1993: Whittemore E R; Korotzer A R; Etebari A; Cotman C W
Carbachol increases intracellular free calcium in cultured rat microglia.
Brain research 1993;621(1):59-64.
1993: Ulas J; Nguyen L; Cotman C W
Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex.
Neuroreport 1993;4(8):1049-51.
1993: Miller S; Bridges R J; Cotman C W
Stimulation of phosphoinositide hydrolysis by trans-(+/-)-ACPD is greatly enhanced when astrocytes are cultured in a serum-free defined medium.
Brain research 1993;618(1):175-8.
1993: Kahle J S; Cotman C W
L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices.
The Journal of pharmacology and experimental therapeutics 1993;266(1):207-15.
1993: Magnusson K R; Cotman C W
Age-related changes in excitatory amino acid receptors in two mouse strains.
Neurobiology of aging 1993;14(3):197-206.
1993: Kahle J S; Ulas J; Cotman C W
Increased sensitivity to adenosine in the rat dentate gyrus molecular layer two weeks after partial entorhinal lesions.
Brain research 1993;609(1-2):201-10.
1993: Pike C J; Burdick D; Walencewicz A J; Glabe C G; Cotman C W
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(4):1676-87.
1993: Vijayan V K; Zhou S S; Russell M J; Geddes J; Ellis W; Cotman C W
Perineuronal satellitosis in the human hippocampal formation.
Hippocampus 1993;3(2):239-50.
1993: Russell M J; Cummings B J; Profitt B F; Wysocki C J; Gilbert A N; Cotman C W
Life span changes in the verbal categorization of odors.
Journal of gerontology 1993;48(2):P49-53.
1993: Gómez-Pinilla F; Cotman C W
Distribution of fibroblast growth factor 5 mRNA in the rat brain: an in situ hybridization study.
Brain research 1993;606(1):79-86.
1993: Magnusson K R; Cotman C W
Effects of aging on NMDA and MK801 binding sites in mice.
Brain research 1993;604(1-2):334-7.
1993: Ulas J; Brunner L C; Nguyen L; Cotman C W
Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: a quantitative autoradiographic study.
Neuroscience 1993;52(4):843-54.
1993: van der Wal E A; Gómez-Pinilla F; Cotman C W
Transforming growth factor-beta 1 is in plaques in Alzheimer and Down pathologies.
Neuroreport 1993;4(1):69-72.
1993: Araujo D M; Cotman C W
Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors.
Brain research 1993;600(1):49-55.
1993: Neal J H; Cotman C W
Human brain tumor cyst fluid is mitogenic for primary astrocytes in culture.
Neurosurgery 1993;32(1):95-8; discussion 98-9.
1993: Cotman C W; Pike C J; Cummings B J
Adaptive versus pathological plasticity. Possible contributions to age-related dementia.
Advances in neurology 1993;59():35-45.
1993: Kahle J S; Cotman C W
Adenosine, L-AP4, and baclofen modulation of paired-pulse potentiation in the dentate gyrus: interstimulus interval-dependent pharmacology.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1993;94(1):97-104.
1993: Ulas J; Cotman C W
Excitatory amino acid receptors in schizophrenia.
Schizophrenia bulletin 1993;19(1):105-17.
1992: Su J H; Cummings B J; Cotman C W
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease.
Neuroscience 1992;51(4):801-13.
1992: Weihmuller F B; Ulas J; Nguyen L; Cotman C W; Marshall J F
Elevated NMDA receptors in parkinsonian striatum.
Neuroreport 1992;3(11):977-80.
1992: Kammesheidt A; Boyce F M; Spanoyannis A F; Cummings B J; Ortegón M; Cotman C; Vaught J L; Neve R L
Deposition of beta/A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxyl-terminal fragment of the Alzheimer amyloid precursor in the brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10857-61.
1992: Cotman C W; Pike C J; Copani A
beta-Amyloid neurotoxicity: a discussion of in vitro findings.
Neurobiology of aging 1992;13(5):587-90.
1992: Cummings B J; Yee G J; Cotman C W
bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy.
Brain research 1992;591(2):271-6.
1992: Bridges R J; Hatalski C G; Shim S N; Cummings B J; Vijayan V; Kundi A; Cotman C W
Gliotoxic actions of excitatory amino acids.
Neuropharmacology 1992;31(9):899-907.
1992: Pike C J; Cummings B J; Cotman C W
beta-Amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer pathology.
Neuroreport 1992;3(9):769-72.
1992: Geddes J W; Ulas J; Brunner L C; Choe W; Cotman C W
Hippocampal excitatory amino acid receptors in elderly, normal individuals and those with Alzheimer's disease: non-N-methyl-D-aspartate receptors.
Neuroscience 1992;50(1):23-34.
1992: Koh J Y; Cotman C W
Programmed cell death: its possible contribution to neurotoxicity mediated by calcium channel antagonists.
Brain research 1992;587(2):233-40.
1992: Gómez-Pinilla F; Cotman C W
Transient lesion-induced increase of basic fibroblast growth factor and its receptor in layer VIb (subplate cells) of the adult rat cerebral cortex.
Neuroscience 1992;49(4):771-80.
1992: Ulas J; Brunner L C; Geddes J W; Choe W; Cotman C W
N-methyl-D-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease.
Neuroscience 1992;49(1):45-61.
1992: Clark A S; Cotman C W
Adrenal hormone effects on hippocampal excitatory amino acid binding.
Brain research 1992;585(1-2):161-8.
1992: Cummings B J; Su J H; Geddes J W; Van Nostrand W E; Wagner S L; Cunningham D D; Cotman C W
Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease.
Neuroscience 1992;48(4):763-77.
1992: Araujo D M; Cotman C W
Basic FGF in astroglial, microglial, and neuronal cultures: characterization of binding sites and modulation of release by lymphokines and trophic factors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(5):1668-78.
1992: Miller S; Cotman C W; Bridges R J
1-Aminocyclopentane-trans-1,3-dicarboxylic acid induces glutamine synthetase activity in cultured astrocytes.
Journal of neurochemistry 1992;58(5):1967-70.
1992: Van Nostrand W E; Wagner S L; Shankle W R; Farrow J S; Dick M; Rozemuller J M; Kuiper M A; Wolters E C; Zimmerman J; Cotman C W
Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):2551-5.
1992: Clark A S; Magnusson K R; Cotman C W
In vitro autoradiography of hippocampal excitatory amino acid binding in aged Fischer 344 rats: relationship to performance on the Morris water maze.
Behavioral neuroscience 1992;106(2):324-35.
1992: Taube J S; Kesslak J P; Cotman C W
Lesions of the rat postsubiculum impair performance on spatial tasks.
Behavioral and neural biology 1992;57(2):131-43.
1992: Emerich D F; Black B A; Kesslak J P; Cotman C W; Walsh T J
Transplantation of fetal cholinergic neurons into the hippocampus attenuates the cognitive and neurochemical deficits induced by AF64A.
Brain research bulletin 1992;28(2):219-26.
1992: Geddes J W; Brunner L; Cotman C W; Buzsáki G
Alterations in [3H]kainate and N-methyl-D-aspartate-sensitive L-[3H]-glutamate binding in the rat hippocampal formation following fimbria-fornix lesions.
Experimental neurology 1992;115(2):271-81.
1992: Burdick D; Soreghan B; Kwon M; Kosmoski J; Knauer M; Henschen A; Yates J; Cotman C; Glabe C
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.
The Journal of biological chemistry 1992;267(1):546-54.
1992: Araujo D M; Cotman C W
Beta-amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease.
Brain research 1992;569(1):141-5.
1992: Gómez-Pinilla F; Lee J W; Cotman C W
Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbria-fornix transection.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(1):345-55.
1992: Korotzer A R; Cotman C W
Voltage-gated currents expressed by rat microglia in culture.
Glia 1992;6(2):81-8.
1992: Cotman C W
An overview and perspective on the potential relevance of neuronal growth to the development of epilepsy and epilepsy-related disturbances.
Epilepsy research. Supplement 1992;9():257-61; discussion 261-4.
1991: Copani A; Koh J Y; Cotman C W
Beta-amyloid increases neuronal susceptibility to injury by glucose deprivation.
Neuroreport 1991;2(12):763-5.
1991: Van Nostrand W E; Farrow J S; Wagner S L; Bhasin R; Goldgaber D; Cotman C W; Cunningham D D
The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10302-6.
1991: Pike C J; Walencewicz A J; Glabe C G; Cotman C W
In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity.
Brain research 1991;563(1-2):311-4.
1991: Koh J Y; Palmer E; Cotman C W
Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9431-5.
1991: Anderson K J; Bridges R J; Cotman C W
Increased density of excitatory amino acid transport sites in the hippocampal formation following an entorhinal lesion.
Brain research 1991;562(2):285-90.
1991: Koh J Y; Palmer E; Lin A; Cotman C W
A metabotropic glutamate receptor agonist does not mediate neuronal degeneration in cortical culture.
Brain research 1991;561(2):338-43.
1991: Buchsbaum M S; Kesslak J P; Lynch G; Chui H; Wu J; Sicotte N; Hazlett E; Teng E; Cotman C W
Temporal and hippocampal metabolic rate during an olfactory memory task assessed by positron emission tomography in patients with dementia of the Alzheimer type and controls. Preliminary studies.
Archives of general psychiatry 1991;48(9):840-7.
1991: Pike C J; Walencewicz A J; Glabe C G; Cotman C W
Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures.
European journal of pharmacology 1991;207(4):367-8.
1991: Kesslak J P; Korotzer A; Song A; Kamali K; Cotman C W
Effects of tetrahydroaminoacridine (THA) on functional recovery after sequential lesion of the entorhinal cortex.
Brain research 1991;557(1-2):57-63.
1991: Whittemore E R; Cotman C W
Agonists selective for phosphoinositide-coupled receptors sensitize neurons to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4).
Brain research 1991;555(2):215-9.
1991: Stevens D R; Cotman C W
Long-term potentiation of excitatory and slow inhibitory synaptic potentials in the hippocampal-septal projection of the rat.
Brain research 1991;558(1):120-2.
1991: Geddes J W; Cotman C W
Plasticity in Alzheimer's disease: too much or not enough?
Neurobiology of aging 1991;12(4):330-3; discussion 352-5.
1991: Vijayan V K; Geddes J W; Anderson K J; Chang-Chui H; Ellis W G; Cotman C W
Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation.
Experimental neurology 1991;112(1):72-8.
1991: Sullivan R M; Taborsky-Barba S; Mendoza R; Itano A; Leon M; Cotman C W; Payne T F; Lott I
Olfactory classical conditioning in neonates.
Pediatrics 1991;87(4):511-8.
1991: Bridges R J; Stanley M S; Anderson M W; Cotman C W; Chamberlin A R
Conformationally defined neurotransmitter analogues. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer.
Journal of medicinal chemistry 1991;34(2):717-25.
1991: Peterson C; Vanderklish P; Seubert P; Cotman C; Lynch G
Increased spectrin proteolysis in fibroblasts from aged and Alzheimer donors.
Neuroscience letters 1991;121(1-2):239-43.
1991: Kesslak J P; Nalcioglu O; Cotman C W
Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease.
Neurology 1991;41(1):51-4.
1991: Bridges R J; Koh J Y; Hatalski C G; Cotman C W
Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione.
European journal of pharmacology 1991;192(1):199-200.
1991: Cotman C W; Gómez-Pinilla F
Basic fibroblast growth factor in the mature brain and its possible role in Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;638():221-31.
1990: Koh J Y; Yang L L; Cotman C W
Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage.
Brain research 1990;533(2):315-20.
1990: Gómez-Pinilla F; Cummings B J; Cotman C W
Induction of basic fibroblast growth factor in Alzheimer's disease pathology.
Neuroreport 1990;1(3-4):211-4.
1990: Peterson C; Giguere J F; Cotman C W; Butterworth R F
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Journal of neurochemistry 1990;55(2):386-90.
1990: Ulas J; Monaghan D T; Cotman C W
Kainate receptors in the rat hippocampus: a distribution and time course of changes in response to unilateral lesions of the entorhinal cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(7):2352-62.
1990: Borg J; Kesslak P J; Cotman C W
Peripheral administration of a long-chain fatty alcohol promotes septal cholinergic neurons survival after fimbria-fornix transection.
Brain research 1990;518(1-2):295-8.
1990: Geddes J W; Cahan L D; Cooper S M; Kim R C; Choi B H; Cotman C W
Altered distribution of excitatory amino acid receptors in temporal lobe epilepsy.
Experimental neurology 1990;108(3):214-20.
1990: Peterson C; Cotman C W
Decreased survival of hippocampal neurons in medium conditioned by fibroblasts from aged and Alzheimer donors.
Brain research 1990;515(1-2):39-44.
1990: Russell M J; Vijayan V K; Gibbs R B; Geddes J W; Jacobson C H; Cotman C W
Long-term survival of neural transplants to senescence in rats.
Experimental neurology 1990;108(2):105-8.
1990: Baudry M; Monaghan D; Cotman C; Altar C A
Regional distribution of alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding sites in rat brain: effect of chemical modification of SH- groups in tissue sections.
Journal of neurochemistry 1990;54(5):1682-8.
1990: Whitson J S; Glabe C G; Shintani E; Abcar A; Cotman C W
Beta-amyloid protein promotes neuritic branching in hippocampal cultures.
Neuroscience letters 1990;110(3):319-24.
1990: Geddes J W; Wong J; Choi B H; Kim R C; Cotman C W; Miller F D
Increased expression of the embryonic form of a developmentally regulated mRNA in Alzheimer's disease.
Neuroscience letters 1990;109(1-2):54-61.
1990: Seubert P; Peterson C; Vanderklish P; Cotman C; Lynch G
Increased spectrin proteolysis in the brindled mouse brain.
Neuroscience letters 1990;108(3):303-8.
1990: Palmer E; Nangel-Taylor K; Krause J D; Roxas A; Cotman C W
Changes in excitatory amino acid modulation of phosphoinositide metabolism during development.
Brain research. Developmental brain research 1990;51(1):132-4.
1990: Poirier J; May P C; Osterburg H H; Geddes J; Cotman C; Finch C E
Selective alterations of RNA in rat hippocampus after entorhinal cortex lesioning.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(1):303-7.
1990: Cotman C W; Geddes J W; Kahle J S
Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms?
Progress in brain research 1990;83():427-34.
1990: Ulas J; Monaghan D T; Cotman C W
Plastic response of hippocampal excitatory amino acid receptors to deafferentation and reinnervation.
Neuroscience 1990;34(1):9-17.
1990: Geddes J W; Wilson M C; Miller F D; Cotman C W
Molecular markers of reactive plasticity.
Advances in experimental medicine and biology 1990;268():425-32.
1990: Anderson K J; Monaghan D T; Bridges R J; Tavoularis A L; Cotman C W
Autoradiographic characterization of putative excitatory amino acid transport sites.
Neuroscience 1990;38(2):311-22.
1990: Cotman C W; Geddes J W; Ulas J; Klein M
Plasticity of excitatory amino acid receptors: implications for aging and Alzheimer's disease.
Progress in brain research 1990;86():55-61.
1990: Cahan L D; Geddes J W; Choi B H; Cotman C
Excitotoxic amino acid receptors in human complex partial epilepsy.
Stereotactic and functional neurosurgery 1990;54-55():21-4.
1990: Geddes J W; Hess E J; Hart R A; Kesslak J P; Cotman C W; Wilson M C
Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker.
Neuroscience 1990;38(2):515-25.
1989: Wagner S L; Geddes J W; Cotman C W; Lau A L; Gurwitz D; Isackson P J; Cunningham D D
Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8284-8.
1989: Cotman C W; Lynch G S
The neurobiology of learning and memory.
Cognition 1989;33(1-2):201-41.
1989: Peterson C; Cotman C W
Strain-dependent decrease in glutamate binding to the N-methyl-D-aspartic acid receptor during aging.
Neuroscience letters 1989;104(3):309-13.
1989: Van Nostrand W E; Wagner S L; Suzuki M; Choi B H; Farrow J S; Geddes J W; Cotman C W; Cunningham D D
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor.
Nature 1989;341(6242):546-9.
1989: Geddes J W; Cotman C W
Plasticity, pathology, and Alzheimer's disease.
Neurobiology of aging 1989;10(5):571-3; discussion 588-90.
1989: Cotman C W; Geddes J W; Bridges R J; Monaghan D T
N-methyl-D-aspartate receptors and Alzheimer's disease.
Neurobiology of aging 1989;10(5):603-5; discussion 618-20.
1989: Joyce J N; Gibbs R B; Cotman C W; Marshall J F
Regulation of muscarinic receptors in hippocampus following cholinergic denervation and reinnervation by septal and striatal transplants.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(8):2776-91.
1989: Brewer G J; Cotman C W
Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen.
Brain research 1989;494(1):65-74.
1989: Peterson C; Neal J H; Cotman C W
Development of N-methyl-D-aspartate excitotoxicity in cultured hippocampal neurons.
Brain research. Developmental brain research 1989;48(2):187-95.
1989: Palmer E; Monaghan D T; Cotman C W
Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor.
European journal of pharmacology 1989;166(3):585-7.
1989: Balázs R; Hack N; Jørgensen O S; Cotman C W
N-methyl-D-aspartate promotes the survival of cerebellar granule cells: pharmacological characterization.
Neuroscience letters 1989;101(3):241-6.
1989: Bridges R J; Stevens D R; Kahle J S; Nunn P B; Kadri M; Cotman C W
Structure-function studies on N-oxalyl-diamino-dicarboxylic acids and excitatory amino acid receptors: evidence that beta-L-ODAP is a selective non-NMDA agonist.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):2073-9.
1989: Gómez-Pinilla F; Tram H; Cotman C W; Nieto-Sampedro M
Neuroprotective effect of MK-801 and U-50488H after contusive spinal cord injury.
Experimental neurology 1989;104(2):118-24.
1989: Brewer G J; Cotman C W
NMDA receptor regulation of neuronal morphology in cultured hippocampal neurons.
Neuroscience letters 1989;99(3):268-73.
1989: Whitson J S; Selkoe D J; Cotman C W
Amyloid beta protein enhances the survival of hippocampal neurons in vitro.
Science (New York, N.Y.) 1989;243(4897):1488-90.
1989: Kahle J S; Cotman C W
Carbachol depresses synaptic responses in the medial but not the lateral perforant path.
Brain research 1989;482(1):159-63.
1989: Westerberg E; Monaghan D T; Kalimo H; Cotman C W; Wieloch T W
Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(3):798-805.
1989: Gómez-Pinilla F; Cotman C W; Nieto-Sampedro M
NGF receptor immunoreactivity in aged rat brain.
Brain research 1989;479(2):255-62.
1989: Geddes J W; Cooper S M; Cotman C W; Patel S; Meldrum B S
N-methyl-D-aspartate receptors in the cortex and hippocampus of baboon (Papio anubis and Papio papio).
Neuroscience 1989;32(1):39-47.
1989: Cotman C; Monaghan D
Multiple excitatory amino acid receptor regulation of intracellular Ca2+. Implications for aging and Alzheimer's disease.
Annals of the New York Academy of Sciences 1989;568():138-48.
1989: Monaghan D T; Bridges R J; Cotman C W
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system.
Annual review of pharmacology and toxicology 1989;29():365-402.
1988: Monaghan D T; Olverman H J; Nguyen L; Watkins J C; Cotman C W
Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9836-40.
1988: Palmer E; Monaghan D T; Cotman C W
Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation.
Brain research 1988;464(2):161-5.
1988: Kesslak J P; Cotman C W; Chui H C; Van den Noort S; Fang H; Pfeffer R; Lynch G
Olfactory tests as possible probes for detecting and monitoring Alzheimer's disease.
Neurobiology of aging 1988;9(4):399-403.
1988: Kesslak J P; Walencewicz A; Calin L; Nieto-Sampedro M; Cotman C W
Hippocampal but not astrocyte transplants enhance recovery on a forced choice alternation task after kainate lesions.
Brain research 1988;454(1-2):347-54.
1988: Lasher R S; Erickson P F; Mena E E; Cotman C W
The binding of a monoclonal antibody reactive with pp60v-src to the rat CNS both in vitro and in vivo: evidence that the epitope is present intracellularly as well as being associated with a number of antigenically related polypeptides located externally in the plasma membrane only in the synaptic region.
Brain research 1988;452(1-2):184-202.
1988: Nieto-Sampedro M; Lim R; Hicklin D J; Cotman C W
Early release of glia maturation factor and acidic fibroblast growth factor after rat brain injury.
Neuroscience letters 1988;86(3):361-5.
1988: Anderson K J; Gibbs R B; Cotman C W
Transmitter phenotype is a major determinant in the specificity of synapses formed by cholinergic neurons transplanted to the hippocampus.
Neuroscience 1988;25(1):19-25.
1988: Lincoln J; Coopersmith R; Harris E W; Cotman C W; Leon M
NMDA receptor activation and early olfactory learning.
Brain research 1988;467(2):309-12.
1988: Anderson K J; Dam D; Lee S; Cotman C W
Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo.
Nature 1988;332(6162):360-1.
1988: Millaruelo A I; Nieto-Sampedro M; Cotman C W
Cooperation between nerve growth factor and laminin or fibronectin in promoting sensory neuron survival and neurite outgrowth.
Brain research 1988;466(2):219-28.
1988: Bridges R J; Kadri M M; Monaghan D T; Nunn P B; Watkins J C; Cotman C W
Inhibition of [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding by the excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid.
European journal of pharmacology 1988;145(3):357-9.
1988: Cotman C W; Anderson K J
Synaptic plasticity and functional stabilization in the hippocampal formation: possible role in Alzheimer's disease.
Advances in neurology 1988;47():313-35.
1988: Joyce J N; Gibbs R B; Cotman C W; Marshall J F
Regulation of acetylcholine muscarinic receptors by embryonic septal grafts showing cholinergic innervation of host hippocampus.
Progress in brain research 1988;78():109-16.
1988: Cotman C W; Kesslak J P
The role of trophic factors in behavioral recovery and integration of transplants.
Progress in brain research 1988;78():311-9.
1988: Cotman C W; Monaghan D T; Ganong A H
Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity.
Annual review of neuroscience 1988;11():61-80.
1987: Gomez-Pinilla F; Cotman C W; Nieto-Sampedro M
NGF receptor immunoreactivity in rat brain: topographic distribution and response to entorhinal ablation.
Neuroscience letters 1987;82(3):260-6.
1987: Needels D L; Nieto-Sampedro M; Cotman C W
Long-term support by injured brain extract of a subpopulation of ciliary ganglion neurons purified by differential adhesion.
Neurochemical research 1987;12(10):901-7.
1987: Gibbs R B; Yu J; Cotman C W
Entorhinal transplants and spatial memory abilities in rats.
Behavioural brain research 1987;26(1):29-35.
1987: Stevens D R; Cotman C W
Excitatory actions of tetrahydro-9-aminoacridine (THA) on hippocampal pyramidal neurons.
Neuroscience letters 1987;79(3):301-5.
1987: Harris E W; Stevens D R; Cotman C W
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Brain research 1987;418(2):361-5.
1987: Rosenblatt D E; Cotman C W; Nieto-Sampedro M; Rowe J W; Knauer D J
Identification of a protease inhibitor produced by astrocytes that is structurally and functionally homologous to human protease nexin-I.
Brain research 1987;415(1):40-8.
1987: Bridges R J; Kesslak J P; Nieto-Sampedro M; Broderick J T; Yu J; Cotman C W
A L-[3H]glutamate binding site on glia: an autoradiographic study on implanted astrocytes.
Brain research 1987;415(1):163-8.
1987: Gibbs R B; Cotman C W
Factors affecting survival and outgrowth from transplants of entorhinal cortex.
Neuroscience 1987;21(3):699-706.
1987: Bridges R J; Nieto-Sampedro M; Kadri M; Cotman C W
A novel chloride-dependent L-[3H]glutamate binding site in astrocyte membranes.
Journal of neurochemistry 1987;48(6):1709-15.
1987: Vijayan V K; Cotman C W
Hydrocortisone administration alters glial reaction to entorhinal lesion in the rat dentate gyrus.
Experimental neurology 1987;96(2):307-20.
1987: Anderson K J; Borja M A; Cotman C W; Moffett J R; Namboodiri M A; Neale J H
N-acetylaspartylglutamate identified in the rat retinal ganglion cells and their projections in the brain.
Brain research 1987;411(1):172-7.
1987: Monaghan D T; Geddes J W; Yao D; Chung C; Cotman C W
[3H]TCP binding sites in Alzheimer's disease.
Neuroscience letters 1987;73(2):197-200.
1987: Westerberg E; Monaghan D T; Cotman C W; Wieloch T
Excitatory amino acid receptors and ischemic brain damage in the rat.
Neuroscience letters 1987;73(2):119-24.
1987: Gibbs R B; Needels D L; Yu J; Cotman C W
Effects of entorhinal lesions on trophic activities present in rat entorhinal cortex and hippocampus as studied using primary cultures of entorhinal and septal tissues.
Journal of neuroscience research 1987;18(2):274-88.
1987: Pixley S K; Nieto-Sampedro M; Cotman C W
Preferential adhesion of brain astrocytes to laminin and central neurites to astrocytes.
Journal of neuroscience research 1987;18(3):402-6.
1987: Nieto-Sampedro M; Kesslak J P; Gibbs R; Cotman C W
Effects of conditioning lesions on transplant survival, connectivity, and function. Role of neurotrophic factors.
Annals of the New York Academy of Sciences 1987;495():108-19.
1986: Geddes J W; Anderson K J; Cotman C W
Senile plaques as aberrant sprout-stimulating structures.
Experimental neurology 1986;94(3):767-76.
1986: Kesslak J P; Brown L; Steichen C; Cotman C W
Adult and embryonic frontal cortex transplants after frontal cortex ablation enhance recovery on a reinforced alternation task.
Experimental neurology 1986;94(3):615-26.
1986: Anderson K J; Monaghan D T; Cangro C B; Namboodiri M A; Neale J H; Cotman C W
Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain.
Neuroscience letters 1986;72(1):14-20.
1986: Geddes J W; Chang-Chui H; Cooper S M; Lott I T; Cotman C W
Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease.
Brain research 1986;399(1):156-61.
1986: Olverman H J; Monaghan D T; Cotman C W; Watkins J C
[3H]CPP, a new competitive ligand for NMDA receptors.
European journal of pharmacology 1986;131(1):161-2.
1986: Monaghan D T; Cotman C W
Identification and properties of N-methyl-D-aspartate receptors in rat brain synaptic plasma membranes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7532-6.
1986: Cotman C W; Flatman J A; Ganong A H; Perkins M N
Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea-pig hippocampus.
The Journal of physiology 1986;378():403-15.
1986: Gibbs R B; Anderson K; Cotman C W
Factors affecting innervation in the CNS: comparison of three cholinergic cell types transplanted to the hippocampus of adult rats.
Brain research 1986;383(1-2):362-6.
1986: Gibbs R B; Pixley S K; Cotman C W
Transplantation of septal neurons maintained in long-term culture.
Brain research 1986;382(2):409-15.
1986: Harris E W; Cotman C W
Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl D-aspartate antagonists.
Neuroscience letters 1986;70(1):132-7.
1986: Geddes J W; Cotman C W
Plasticity in hippocampal excitatory amino acid receptors in Alzheimer's disease.
Neuroscience research 1986;3(6):672-8.
1986: Harris E W; Ganong A H; Monaghan D T; Watkins J C; Cotman C W
Action of 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP): a new and highly potent antagonist of N-methyl-D-aspartate receptors in the hippocampus.
Brain research 1986;382(1):174-7.
1986: Stevens D R; Cotman C W
Excitatory amino acid antagonists depress transmission in hippocampal projections to the lateral septum.
Brain research 1986;382(2):437-40.
1986: Hearn T J; Ganong A H; Cotman C W
Antagonism of lateral olfactory tract synaptic potentials in rat prepyriform cortex slices.
Brain research 1986;379(2):372-6.
1986: Needels D L; Nieto-Sampedro M; Cotman C W
Induction of a neurite-promoting factor in rat brain following injury or deafferentation.
Neuroscience 1986;18(3):517-26.
1986: Monaghan D T; Nguyen L; Cotman C W
The distribution of [3H]kainate binding sites in primate hippocampus is similar to the distribution of both Ca2+-sensitive and Ca2+-insensitive [3H]kainate binding sites in rat hippocampus.
Neurochemical research 1986;11(7):1073-82.
1986: Anderson K J; Gibbs R B; Salvaterra P M; Cotman C W
Ultrastructural characterization of identified cholinergic neurons transplanted to the hippocampal formation of the rat.
The Journal of comparative neurology 1986;249(2):279-92.
1986: Bridges R J; Hearn T J; Monaghan D T; Cotman C W
A comparison of 2-amino-4-phosphonobutyric acid (AP4) receptors and [3H]AP4 binding sites in the rat brain.
Brain research 1986;375(1):204-9.
1986: Kesslak J P; Nieto-Sampedro M; Globus J; Cotman C W
Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation.
Experimental neurology 1986;92(2):377-90.
1986: Millaruelo A I; Nieto-Sampedro M; Yu J; Cotman C W
Neurotrophic activity in the central and peripheral nervous systems of the cat. Effects of injury.
Brain research 1986;374(1):12-20.
1986: Ganong A H; Jones A W; Watkins J C; Cotman C W
Parallel antagonism of synaptic transmission and kainate/quisqualate responses in the hippocampus by piperazine-2,3-dicarboxylic acid analogs.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):930-7.
1986: Thompson R; Gibbs R B; Ristic G A; Cotman C W; Yu J
Lack of correlation between cortical levels of choline acetyltransferase and learning scores in rats with globus pallidus lesions.
Brain research 1986;367(1-2):402-4.
1986: Anderson K J; Holets V R; Mazur P C; Lasher R S; Cotman C W
Immunocytochemical localization of serotonin in the rat dentate gyrus following raphe transplants.
Brain research 1986;369(1-2):21-8.
1986: Ganong A H; Cotman C W
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
The Journal of pharmacology and experimental therapeutics 1986;236(1):293-9.
1986: Thompson R; Gibbs R B; Ristic G A; Cotman C W; Yu J
Learning deficits in rats with early neurotoxic lesions to the globus pallidus, substantia nigra, median raphe or pontine reticular formation.
Physiology & behavior 1986;37(1):141-51.
1986: Cotman C W; Monaghan D T
Anatomical organization of excitatory amino acid receptors and their properties.
Advances in experimental medicine and biology 1986;203():237-52.
1986: Pixley S K; Cotman C W
Laminin supports short-term survival of rat septal neurons in low-density, serum-free cultures.
Journal of neuroscience research 1986;15(1):1-17.
1985: Geddes J W; Monaghan D T; Cotman C W; Lott I T; Kim R C; Chui H C
Plasticity of hippocampal circuitry in Alzheimer's disease.
Science (New York, N.Y.) 1985;230(4730):1179-81.
1985: Monaghan D T; Cotman C W
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(11):2909-19.
1985: Nieto-Sampedro M; Needels D L; Cotman C W
A simple, objective method to measure the activity of factors that promote neuronal survival.
Journal of neuroscience methods 1985;15(1):37-48.
1985: Nieto-Sampedro M; Saneto R P; de Vellis J; Cotman C W
The control of glial populations in brain: changes in astrocyte mitogenic and morphogenic factors in response to injury.
Brain research 1985;343(2):320-8.
1985: Monaghan D T; Yao D; Cotman C W
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Brain research 1985;340(2):378-83.
1985: Mena E E; Cotman C W
Pathologic concentrations of ammonium ions block L-glutamate uptake.
Experimental neurology 1985;89(1):259-63.
1985: Gibbs R B; Harris E W; Cotman C W
Replacement of damaged cortical projections by homotypic transplants of entorhinal cortex.
The Journal of comparative neurology 1985;237(1):47-64.
1985: Whittemore S R; Nieto-Sampedro M; Needels D L; Cotman C W
Neuronotrophic factors for mammalian brain neurons: injury induction in neonatal, adult and aged rat brain.
Brain research 1985;352(2):169-78.
1985: Harris E W; Cotman C W
Effects of synaptic antagonists on perforant path paired-pulse plasticity: differentiation of pre- and postsynaptic antagonism.
Brain research 1985;334(2):348-53.
1985: Altschuler R A; Monaghan D T; Haser W G; Wenthold R J; Curthoys N P; Cotman C W
Immunocytochemical localization of glutaminase-like and aspartate aminotransferase-like immunoreactivities in the rat and guinea pig hippocampus.
Brain research 1985;330(2):225-33.
1985: Mena E E; Monaghan D T; Whittemore S R; Cotman C W
Cations differentially affect subpopulations of L-glutamate receptors in rat synaptic plasma membranes.
Brain research 1985;329(1-2):319-22.
1985: Needels D L; Nieto-Sampedro M; Whittemore S R; Cotman C W
Neuronotrophic activity for ciliary ganglion neurons. Induction following injury to the brain of neonatal, adult, and aged rats.
Brain research 1985;350(1-2):275-84.
1985: Cotman C W; Nieto-Sampedro M
Progress in facilitating the recovery of function after central nervous system trauma.
Annals of the New York Academy of Sciences 1985;457():83-104.
1984: Harris E W; Ganong A H; Cotman C W
Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors.
Brain research 1984;323(1):132-7.
1984: Monaghan D T; Yao D; Olverman H J; Watkins J C; Cotman C W
Autoradiography of D-2-[3H]amino-5-phosphonopentanoate binding sites in rat brain.
Neuroscience letters 1984;52(3):253-8.
1984: Mena E E; Whittemore S R; Monaghan D T; Cotman C W
Ionic regulation of glutamate binding sites.
Life sciences 1984;35(24):2427-33.
1984: Monaghan D T; Yao D; Cotman C W
Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography.
Brain research 1984;324(1):160-4.
1984: Nieto-Sampedro M; Whittemore S R; Needels D L; Larson J; Cotman C W
The survival of brain transplants is enhanced by extracts from injured brain.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(19):6250-4.
1984: Cotman C W; Nieto-Sampedro M
Cell biology of synaptic plasticity.
Science (New York, N.Y.) 1984;225(4668):1287-94.
1984: Holets V R; Cotman C W
Postnatal development of the serotonin innervation of the hippocampus and dentate gyrus following raphe implants.
The Journal of comparative neurology 1984;226(4):457-76.
1984: Cotman C W
In memoriam: Henry R. Mahler 1921-1983.
Journal of neurochemistry 1984;42(4):1200-2.
1984: DeKosky S T; Scheff S W; Cotman C W
Elevated corticosterone levels. A possible cause of reduced axon sprouting in aged animals.
Neuroendocrinology 1984;38(1):33-8.
1984: Lanthorn T H; Ganong A H; Cotman C W
2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not rat hippocampus.
Brain research 1984;290(1):174-8.
1984: Harris E W; Cotman C W
Brain tissue transplantation research.
Applied neurophysiology 1984;47(1-2):9-15.
1984: Cotman C W; Nieto-Sampedro M; Gibbs R B
Enhancing the self-repairing potential of the CNS after injury.
Central nervous system trauma : journal of the American Paralysis Association 1984;1(1):3-14.
1983: Lanthorn T H; Cotman C W
Relative potency of analogues of excitatory amino acids on hippocampal CA1 neurons.
Neuropharmacology 1983;22(12A):1343-8.
1983: Monaghan D T; McMills M C; Chamberlin A R; Cotman C W
Synthesis of [3H]2-amino-4-phosphonobutyric acid and characterization of its binding to rat brain membranes: a selective ligand for the chloride/calcium-dependent class of L-glutamate binding sites.
Brain research 1983;278(1-2):137-44.
1983: Nieto-Sampedro M; Manthrope M; Barbin G; Varon S; Cotman C W
Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(11):2219-29.
1983: Monaghan D T; Holets V R; Toy D W; Cotman C W
Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites.
Nature 1983;306(5939):176-9.
1983: Whittemore S R; Mena E E; Monaghan D T; Cotman C W
Regional distribution and ionic requirement of Cl-/Ca2+-activated and Cl-/Ca2+-independent glutamate receptors in rat brain.
Brain research 1983;277(1):99-107.
1983: Ganong A H; Lanthorn T H; Cotman C W
Kynurenic acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord.
Brain research 1983;273(1):170-4.
1983: Fagg G E; Mena E E; Monaghan D T; Cotman C W
Freezing eliminates a specific population of L-glutamate receptors in synaptic membranes.
Neuroscience letters 1983;38(2):157-62.
1983: Manthorpe M; Nieto-Sampedro M; Skaper S D; Lewis E R; Barbin G; Longo F M; Cotman C W; Varon S
Neuronotrophic activity in brain wounds of the developing rat. Correlation with implant survival in the wound cavity.
Brain research 1983;267(1):47-56.
1983: Koerner J F; Cotman C W
A microperfusion chamber for brain slice pharmacology.
Journal of neuroscience methods 1983;7(3):243-51.
1983: Fagg G E; Foster A C; Mena E E; Cotman C W
Chloride and calcium ions separate L-glutamate receptor populations in synaptic membranes.
European journal of pharmacology 1983;88(1):105-10.
1983: Wendt J S; Fagg G E; Cotman C W
Regeneration of rat hippocampal fimbria fibers after fimbria transection and peripheral nerve or fetal hippocampal implantation.
Experimental neurology 1983;79(2):452-61.
1983: Lewis E R; Cotman C W
Neurotransmitter characteristics of brain grafts: striatal and septal tissues form the same laminated input to the hippocampus.
Neuroscience 1983;8(1):57-66.
1983: Vijayan V K; Cotman C W
Lysosomal enzyme changes in young and aged control and entorhinal-lesioned rats.
Neurobiology of aging 1983;4(1):13-23.
1983: Cotman C W; Hoff S F
Synapse repair in the hippocampus: the effects of aging.
Birth defects original article series 1983;19(4):119-34.
1983: Harris E W; Cotman C W
Effects of acidic amino acid antagonists on paired-pulse potentiation at the lateral perforant path.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1983;52(3):455-60.
1983: Fagg G E; Mena E E; Cotman C W
L-glutamate receptor populations in synaptic membranes: effects of ions and pharmacological characteristics.
Advances in biochemical psychopharmacology 1983;37():199-209.
1982: Monaghan D T; Cotman C W
The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography.
Brain research 1982;252(1):91-100.
1982: Ganong A H; Cotman C W
Acidic amino acid antagonists of lateral perforant path synaptic transmission: agonist-antagonist interactions in the dentate gyrus.
Neuroscience letters 1982;34(2):195-200.
1982: Koerner J F; Cotman C W
Response of Schaffer collateral-CA 1 pyramidal cell synapses of the hippocampus to analogues of acidic amino acids.
Brain research 1982;251(1):105-15.
1982: Sampedro M N; Bussineau C M; Cotman C W
Turnover of brain postsynaptic densities after selective deafferentation: detection by means of an antibody to antigen PSD-95.
Brain research 1982;251(2):211-20.
1982: Nieto-Sampedro M; Hoff S F; Cotman C W
Perforated postsynaptic densities: probable intermediates in synapse turnover.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(18):5718-22.
1982: Nieto-Sampedro M; Lewis E R; Cotman C W; Manthorpe M; Skaper S D; Barbin G; Longo F M; Varon S
Brain injury causes a time-dependent increase in neuronotrophic activity at the lesion site.
Science (New York, N.Y.) 1982;217(4562):860-1.
1982: Fagg G E; Foster A C; Harris E W; Lanthorn T H; Cotman C W
Structure--activity relationships of L-glutamate receptor ligands: role of the omega-acidic terminal.
Neuroscience letters 1982;31(1):59-64.
1982: Mena E E; Fagg G E; Cotman C W
Chloride ions enhance L-glutamate binding to rat brain synaptic membranes.
Brain research 1982;243(2):378-81.
1982: Fagg G E; Foster A C; Mena E E; Cotman C W
Chloride and calcium ions reveal a pharmacologically distinct population of L-glutamate binding sites in synaptic membranes: correspondence between biochemical and electrophysiological data.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(7):958-65.
1982: Nieto-Sampedro M; Bussineau C M; Cotman C W
Isolation, morphology, and protein and glycoprotein composition of synaptic junctional fractions from the brain of lower vertebrates: antigen PSD-95 as a junctional marker.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(6):722-34.
1982: Scheff S W; Cotman C W
Chronic glucocorticoid therapy alters axon sprouting in the hippocampal dentate gyrus.
Experimental neurology 1982;76(3):644-54.
1982: Foster A C; Fagg G E; Harris E W; Cotman C W
Regulation of glutamate receptors: possible role of phosphatidylserine.
Brain research 1982;242(2):374-7.
1982: Mena E E; Cotman C W
Synaptic cleft glycoproteins contain homologous amino acid sequences.
Science (New York, N.Y.) 1982;216(4544):422-4.
1982: Hoff S F; Scheff S W; Cotman C W
Lesion-induced synaptogenesis in the dentate gyrus of aged rats: II. Demonstration of an impaired degeneration clearing response.
The Journal of comparative neurology 1982;205(3):253-9.
1982: Hoff S F; Scheff S W; Benardo L S; Cotman C W
Lesion-induced synaptogenesis in the dentate gyrus of aged rats: I. Loss and reacquisition of normal synaptic density.
The Journal of comparative neurology 1982;205(3):246-52.
1982: Monaghan D T; Mena E E; Cotman C W
The effect of entorhinal cortical ablation on the distribution of muscarinic cholinergic receptors in the rat hippocampus.
Brain research 1982;234(2):480-5.
1982: Lewis E R; Cotman C W
Mechanisms of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. III. Competitive interactions.
Brain research 1982;233(1):29-44.
1982: Lewis E R; Cotman C W
Mechanisms of septal lamination in the developing hippocampus analyzed by outgrowth of fibers from septal implants. II. Absence of guidance by degenerative debris.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(1):66-77.
1982: Beach R L; Bathgate S L; Cotman C W
Identification of cell types in rat hippocampal slices maintained in organotypic cultures.
Brain research 1982;255(1):3-20.
1982: Cotman C W; Nieto-Sampedro M
Brain function, synapse renewal, and plasticity.
Annual review of psychology 1982;33():371-401.
1981: Fagg G E; Scheff S W; Cotman C W
Axonal sprouting at the neuromuscular junction of adult and aged rats.
Experimental neurology 1981;74(3):847-54.
1981: Mena E E; Foster A C; Fagg G E; Cotman C W
Identification of synapse specific components: synaptic glycoproteins, proteins, and transmitter binding sites.
Journal of neurochemistry 1981;37(6):1557-66.
1981: Foster A C; Fagg G E; Mena E E; Cotman C W
L-glutamate and L-aspartate bind to separate sites in rat brain synaptic membranes.
Brain research 1981;229(1):246-50.
1981: Beach R L; Kelly P T; Babitch J A; Cotman C W
Identification of myosin in isolated synaptic junctions.
Brain research 1981;225(1):75-93.
1981: Lanthorn T H; Cotman C W
Baclofen selectively inhibits excitatory synaptic transmission in the hippocampus.
Brain research 1981;225(1):171-8.
1981: Hoff S F; Scheff S W; Kwan A Y; Cotman C W
A new type of lesion-induced synaptogenesis: II. The effect of aging on synaptic turnover in non-denervated zones.
Brain research 1981;222(1):15-27.
1981: Hoff S F; Scheff S W; Kwan A Y; Cotman C W
A new type of lesion-induced synaptogenesis: I. Synaptic turnover in non-denervated zones of the dentate gyrus in young adult rats.
Brain research 1981;222(1):1-13.
1981: Sampedro M N; Bussineau C M; Cotman C W
Postsynaptic density antigens: preparation and characterization of an antiserum against postsynaptic densities.
The Journal of cell biology 1981;90(3):675-86.
1981: Cotman C W; Nieto-Sampedro M; Harris E W
Synapse replacement in the nervous system of adult vertebrates.
Physiological reviews 1981;61(3):684-784.
1981: Koerner J F; Cotman C W
Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex.
Brain research 1981;216(1):192-8.
1981: Foster A C; Mena E E; Fagg G E; Cotman C W
Glutamate and aspartate binding sites are enriched in synaptic junctions isolated from rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(6):620-5.
1981: Nieto-Sampedro M; Bussineau C M; Cotman C W
Optimal concentration of iodonitrotetrazolium for the isolation of junctional fractions from rat brain.
Neurochemical research 1981;6(3):307-20.
1981: Nadler J V; Perry B W; Gentry C; Cotman C W
Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid.
The Journal of comparative neurology 1981;196(4):549-69.
1981: Kelly P T; Cotman C W
Developmental changes in morphology and molecular composition of isolated synaptic junctional structures.
Brain research 1981;206(2):251-7.
1981: Foster A C; Mena E E; Monaghan D T; Cotman C W
Synaptic localization of kainic acid binding sites.
Nature 1981;289(5793):73-5.
1981: Mena E E; Monaghan D T; Cotman C W
Lesion-induced alterations of lectin binding sites in the rat dentate gyrus.
Neuroscience 1981;6(10):1975-83.
1981: Cotman C W; Foster A; Lanthorn T
An overview of glutamate as a neurotransmitter.
Advances in biochemical psychopharmacology 1981;27():1-27.
1980: Scheff S W; Benardo L S; Cotman C W
Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal.
Brain research 1980;199(1):21-38.
1980: Lewis E R; Cotman C W
Mechanisms of septal lamination in the developing hippocampus revealed by outgrowth of fibers from septal implants. I. Positional and temporal factors.
Brain research 1980;196(2):307-30.
1980: Nadler J V; Perry B W; Gentry C; Cotman C W
Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid.
The Journal of comparative neurology 1980;192(2):333-59.
1980: Nadler J V; Perry B W; Gentry C; Cotman C W
Loss and reacquisition of hippocampal synapses after selective destruction of CA3-CA4 afferents with kainic acid.
Brain research 1980;191(2):387-403.
1980: Lewis E R; Cotman C W
Factors specifying the development of synapse number in the rat dentate gyrus: effects of partial target loss.
Brain research 1980;191(1):35-52.
1980: Nieto-Sampedro M; Shelton D; Cotman C W
Specific binding of kainic acid to purified subcellular fractions from rat brain.
Neurochemical research 1980;5(6):591-604.
1980: Lewis E R; Mueller J C; Cotman C W
Neonatal septal implants: development of afferent lamination in the rat dentate gyrus.
Brain research bulletin 1980;5(3):217-21.
1980: Scheff S W; Benardo L S; Cotman C W
Hydrocortison administration retards axon sprouting in the rat dentate gyrus.
Experimental neurology 1980;68(1):195-201.
1980: Nadler J V; Perry B W; Cotman C W
Interaction with CA4-derived fibers accounts for distribution of septohippocampal fibers in rat fascia dentata after entorhinal lesion.
Experimental neurology 1980;68(1):185-94.
1980: Nadler J V; Shelton D L; Perry B W; Cotman C W
Regional distribution of [3H]kainic acid after intraventricular injection.
Life sciences 1980;26(2):133-8.
1980: Nadler J V; Perry B W; Cotman C W
Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid.
Brain research 1980;182(1):1-9.
1980: Goldowitz D; Cotman C W
Do neurotrophic interactions control synapse formation in the adult rat brain?
Brain research 1980;181(2):325-44.
1980: Goldowitz D; Cotman C W
Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study.
Neuroscience 1980;5(12):2163-74.
1979: White W F; Nadler J V; Cotman C W
Analysis of short-term plasticity at the perforant path-granule cell synapse.
Brain research 1979;178(1):41-53.
1979: Goldowitz D; Scheff S W; Cotman C W
The specificity of reactive synaptogenesis: a comparative study in the adult rat hippocampal formation.
Brain research 1979;170(3):427-41.
1979: Hamberger A; Chiang G H; Sandoval E; Cotman C W
Glutamate as a CNS transmitter. II. Regulation of synthesis in the releasable pool.
Brain research 1979;168(3):531-41.
1979: Hamberger A C; Chiang G H; Nylén E S; Scheff S W; Cotman C W
Glutamate as a CNS transmitter. I. Evaluation of glucose and glutamine as precursors for the synthesis of preferentially released glutamate.
Brain research 1979;168(3):513-30.
1979: Rostas J A; Kelly P T; Pesin R H; Cotman C W
Protein and glycoprotein composition of synaptic junctions prepared from discrete synaptic regions and different species.
Brain research 1979;168(1):151-67.
1979: Nadler J V; Shelton D L; Cotman C W
Lesion-induced plasticity of high affinity choline uptake in the developing rat fascia dentata.
Brain research 1979;164():207-16.
1979: Shelton D L; Nadler J V; Cotman C W
Development of high affinity choline uptake and associated acetylcholine synthesis in the rat fascia dentata.
Brain research 1979;163(2):263-75.
1979: White W F; Nadler J V; Cotman C W
The effect of acidic amino acid antagonists on synaptic transmission in the hippocampal formation in vitro.
Brain research 1979;164():177-94.
1979: Kelly P T; Cotman C W; Largen M
Cyclic AMP-stimulated protein kinases at brain synaptic junctions.
The Journal of biological chemistry 1979;254(5):1564-75.
1979: Cotman C W; Scheff S W
Compensatory synapse growth in aged animals after neuronal death.
Mechanisms of ageing and development 1979;9(1-2):103-17.
1979: Cotman C W
Specificity of synaptic growth in brain: remodeling induced by kainic acid lesions.
Progress in brain research 1979;51():203-15.
1979: Haycock J W; Levy W B; Denner L A; Cotman C W
Stimulus-secretion coupling processes in brain: dependence upon extracellular calcium concentration.
Neuroscience 1979;4(9):1341-6.
1978: Scheff S W; Benardo L S; Cotman C W
Lesion-induced vascular changes in the dentate gyrus following removal of the entorhinal cortex in adult rats.
Experimental neurology 1978;62(3):815-20.
1978: Scheff S W; Bernardo L S; Cotman C W
Decrease in adrenergic axon sprouting in the senescent rat.
Science (New York, N.Y.) 1978;202(4369):775-8.
1978: Hamberger A; Cummins J T; Keller E; Cotman C W
Glutamate secretion and NAD(P)H levels during calcium-dependent depolarization of slices of the dentate gyrus.
Brain research 1978;156(2):253-64.
1978: Kelly P T; Cotman C W
Synaptic proteins. Characterization of tubulin and actin and identification of a distinct postsynaptic density polypeptide.
The Journal of cell biology 1978;79(1):173-83.
1978: Haycock J W; Levy W B; Cotman C W
Stimulation-dependent depression of neurotransmitter release in brain: [Ca2+]o dependence.
Brain research 1978;155(1):192-5.
1978: White W F; Nadler J V; Cotman C W
A perfusion chamber for the study of CNS physiology and pharmacology in vitro.
Brain research 1978;152(3):591-6.
1978: Goldwitz D; Cotman C W
Induction of extensive fimbrial branching in the adult rat brain.
Nature 1978;275(5675):64-7.
1978: Scheff S W; Benardo L S; Cotman C W
Effect of serial lesions on sprouting in the dentate gyrus: onset and decline of the catalytic effect.
Brain research 1978;150(1):45-53.
1978: Nadler J V; White W F; Vaca K W; Perry B W; Cotman C W
Biochemical correlates of transmission mediated by glutamate and aspartate.
Journal of neurochemistry 1978;31(1):147-55.
1978: Haycock J W; Levy W B; Denner L A; Cotman C W
Effects of elevated [K+]O on the release of neurotransmitters from cortical synaptosomes: efflux or secretion?
Journal of neurochemistry 1978;30(5):1113-25.
1978: Hamberger A; Chiang G; Nylén E S; Scheff S W; Cotman C W
Stimulus evoked increase in the biosynthesis of the putative neurotransmitter glutamate in the hippocampus.
Brain research 1978;143(3):549-55.
1978: Nadler J V; Cotman C W
Interactions between afferents to the dentate gyrus after entorhinal lesion during development: long-term regulation of choline acetyl-transferase activity.
Brain research 1978;142(1):174-81.
1978: Nadler J V; Perry B W; Cotman C W
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells.
Nature 1978;271(5646):676-7.
1978: Sandoval M E; Horch P; Cotman C W
Evaluation of glutamate as a hippocampal neurotransmitter: glutamate uptake and release from synaptosomes.
Brain research 1978;142(2):285-99.
1978: Haycock J W; White W F; Cotman C W
Differences in alkaline earth stimulation of neurotransmitter release from isolated brain synaptosomes.
Naunyn-Schmiedeberg's archives of pharmacology 1978;301(3):175-9.
1978: Sandoval M E; Cotman C W
Evaluation of glutamate as a neurotransmitter of cerebellar parallel fibers.
Neuroscience 1978;3(2):199-206.
1977: Haycock J W; White W F; McGaugh J L; Cotman C W
Enhanced stimulus--secretion coupling from brains of aged mice.
Experimental neurology 1977;57(3):873-82.
1977: White W F; Nadler J V; Hamberger A; Cotman C W; Cummins J T
Glutamate as transmitter of hippocampal perforant path.
Nature 1977;270(5635):356-7.
1977: Scheff S W; Cotman C W
Recovery of spontaneous alternation following lesions of the entorhinal cortex in adult rats: possible correlation to axon sprouting.
Behavioral biology 1977;21(2):286-93.
1977: Steward O; White W F; Cotman C W
Potentiation of the excitatory synaptic action of commissural, associational and entorhinal afferents to dentate granule cells.
Brain research 1977;134(3):551-60.
1977: Cotman C; Gentry C; Steward O
Synaptic replacement in the dentate gyrus after unilateral entorhinal lesion: electron microscopic analysis of the extent of replacement of synapses by the remaining entorhinal cortex.
Journal of neurocytology 1977;6(4):455-64.
1977: Nadler J V; White W F; Vaca K W; Cotman C W
Calcium-dependent gamma-aminobutyrate release by interneurons of rat hippocampal regions: lesion-induced plasticity.
Brain research 1977;131(2):241-58.
1977: Scheff S; Benardo I; Cotman C
Progressive brain damage accelerates axon sprouting in the adult rat.
Science (New York, N.Y.) 1977;197(4305):795-7.
1977: Yen S H; Liem R K; Kelly P T; Cotman C W; Shelanski M L
Membrane linked proteins at CNS synapses.
Brain research 1977;132(1):172-5.
1977: Nadler J V; White W F; Vaca K W; Redburn D A; Cotman C W
Characterization of putative amino acid transmitter release from slices of rat dentate gyrus.
Journal of neurochemistry 1977;29(2):279-90.
1977: Rostas J A; Kelly P T; Cotman C W
The identification of membrane glycocomponents in polyacrylamide gels: a rapid method using 125I-labeled lectins.
Analytical biochemistry 1977;80(2):366-72.
1977: Feit H; Kelly P; Cotman C W
Identification of a protein related to tubulin in the postsynaptic density.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(3):1047-51.
1977: Nadler J V; Cotman C W; Paoletti C; Lynch G S
Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. II. Effects of partial entorhinal and simultaneous multiple lesions.
The Journal of comparative neurology 1977;171(4):589-604.
1977: Nadler J V; Cotman C W; Lynch G S
Histochemical evidence of altered development of cholinergic fibers in the rat dentate gyrus following lesions. I. Time course after complete unilateral entorhinal lesion at various ages.
The Journal of comparative neurology 1977;171(4):561-87.
1977: Loy R; Lynch G; Cotman C W
Development of afferent lamination in the fascia dentata of the rat.
Brain research 1977;121(2):229-43.
1977: Kelly P T; Cotman C W
Identification of glycoproteins and proteins at synapses in the central nervous system.
The Journal of biological chemistry 1977;252(2):786-93.
1977: Lynch G; Gall C; Cotman C
Temporal parameters of axon "sprouting" in the brain of the adult rat.
Experimental neurology 1977;54(1):179-83.
1977: Haycock J W; Levy W B; Cotman C W
Pentobarbital depression of stimulus-secretion coupling in brain--selective inhibition of depolarization-induced calcium-dependent release.
Biochemical pharmacology 1977;26(2):159-61.
1976: Kelly P T; Cotman C W
Intermolecular disulfide bonds at central nervous system synaptic junctions.
Biochemical and biophysical research communications 1976;73(4):858-64.
1976: Cotman C W; Haycock J W; Levy W B
On the functional coupling of neurotransmitter uptake and release in brain.
British journal of pharmacology 1976;58(4):569-72.
1976: West J R; Deadwyler S A; Cotman C W; Lynch G S
An experimental test of diaschisis.
Behavioral biology 1976;18(3):419-25.
1976: Kelly P; Cotman C W; Gentry C; Nicolson G L
Distribution and mobility of lectin receptors on synaptic membranes of identified neurons in the central nervous system.
The Journal of cell biology 1976;71(2):487-96.
1976: Matthews D A; Cotman C; Lynch G
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts.
Brain research 1976;115(1):23-41.
1976: Matthews D A; Cotman C; Lynch G
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration.
Brain research 1976;115(1):1-21.
1976: Levy W B; Haycock J W; Cotman C W
Stimulation-dependent depression of readily releasable neurotransmitter pools in brain.
Brain research 1976;115(2):243-56.
1976: Churchill L; Cotman C; Banker G; Kelly P; Shannon L
Carbohydrate composition of central nervous system synapses. Analysis of isolated synaptic junctional complexes and postsynaptic densities.
Biochimica et biophysica acta 1976;448(1):57-72.
1976: White W F; Goldowitz D; Lynch G; Cotman C W
Electrophysiological analysis of the projection from the contralateral entorhinal cortex to the dentate gyrus in normal rats.
Brain research 1976;114(2):201-9.
1976: Steward O; Cotman C; Lynch G
A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions.
Brain research 1976;114(2):181-200.
1976: Lynch G; Gall C; Rose G; Cotman C
Changes in the distribution of the dentate gyrus associational system following unilateral or bilateral entorhinal lesions in the adult rat.
Brain research 1976;110(1):57-71.
1976: Spencer H J; Gribkoff V K; Cotman C W; Lynch G S
GDEE antagonism of iontophoretic amino acid excitations in the intact hippocampus and in the hippocampal slice preparation.
Brain research 1976;105(3):471-81.
1976: Nadler J V; Vaca K W; White W F; Lynch G S; Cotman C W
Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents.
Nature 1976;260(5551):538-40.
1976: Dudek F E; Deadwyler S A; Cotman C W; Lynch G
Intracellular responses from granule cell layer in slices of rat hippocampus: perforant path synapse.
Journal of neurophysiology 1976;39(2):384-93.
1976: Redburn D A; Shelton D; Cotman C W
Calcium-dependent release of exogenously loaded gamma-amino-[U-14C]butyrate from synaptosomes: time course of stimulation by potassium, veratridine, and the calcium ionophore, A23187.
Journal of neurochemistry 1976;26(2):297-303.
1976: Rose G; Lynch G; Cotman C W
Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus.
Brain research bulletin 1976;1(1):87-92.
1976: Deadwyler S A; Gribkoff V; Cotman C; Lynch G
Long lasting changes in the spontaneous activity of hippocampal neurons following stimulation of the entorhinal cortex.
Brain research bulletin 1976;1(1):1-7.
1976: Cotman C W; Haycock J W; White W F
Stimulus-secretion coupling processes in brain: analysis of noradrenaline and gamma-aminobutyric acid release.
The Journal of physiology 1976;254(2):475-505.
1976: Cotman C W
Lesion-induced synaptogenesis in brain: a study of dynamic changes in neuronal membrane specializations.
Journal of supramolecular structure 1976;4(3):319-27.
1975: West J R; Deadwyler S; Cotman C W; Lynch G
Time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats.
Brain research 1975;97(2):215-33.
1975: Deadwyler S A; West J R; Cotman C W; Lynch G
Physiological studies of the reciprocal connections between the hippocampus and entorhinal cortex.
Experimental neurology 1975;49(1 Pt 1):35-57.
1975: West J R; Deadwyler S A; Cotman C W; Lynch G
A dual marking technique for microelectrode tracks and localization recording sites.
Electroencephalography and clinical neurophysiology 1975;39(4):407-10.
1975: Redburn D A; Biela J; Shelton D L; Cotman C W
Stimulus secretion coupling in vitro: a rapid perfusion apparatus for monitoring efflux of transmitter substances from tissue samples.
Analytical biochemistry 1975;67(1):268-78.
1975: Goldowitz D; White W F; Steward O; Lynch G; Cotman C
Anatomical evidence for a projection from the entorhinal cortex to the contralateral dentate gyrus of the rat.
Experimental neurology 1975;47(3):433-41.
1975: Deadwyler S A; Dudek F E; Cotman C W; Lynch G
Intracellular responses of rat dentate granule cells in vitro: posttetanic potentiation to perforant path stimulation.
Brain research 1975;88(1):80-5.
1975: Drucker-Colín R R; Spanis C W; Cotman C W; McGaugh J L
Changes in protein levels in perfusates of freely moving cats: relation to behavioral state.
Science (New York, N.Y.) 1975;187(4180):963-5.
1975: Russell R W; Overstreet D H; Cotman C W; Carson V G; Churchill L; Dalglish F W; Vasquez B J
Experimental tests of hypotheses about neurochemical mechanisms underlying behavioral tolerance to the anticholinesterase, diisopropyl fluorophosphate.
The Journal of pharmacology and experimental therapeutics 1975;192(1):73-85.
1975: Deadwyler S A; West J R; Cotman C W; Lynch G S
A neurophysiological analysis of commissural projections to dentate gyrus of the rat.
Journal of neurophysiology 1975;38(1):167-84.
1974: Chippendale T J; Cotman C W; Kozar M D; Lynch G S
Analysis of acetylcholinesterase synthesis and transport in the rat hippocampus: recovery of acetylcholinesterase activity in the septum and hippocampus after administration of diisopropylfluorophosphate.
Brain research 1974;81(3):485-96.
1974: Banker G; Churchill L; Cotman C W
Proteins of the postsynaptic density.
The Journal of cell biology 1974;63(2 Pt 1):456-65.
1974: Nadler J V; Cotman C W; Lynch G S
Biochemical plasticity of short-axon interneurons: increased glutamate decarboxylase activity in the denervated area of rat dentate gyrus following entorhinal lesion.
Experimental neurology 1974;45(2):403-13.
1974: Cotman C W; Banker G; Churchill L; Taylor D
Isolation of postsynaptic densities from rat brain.
The Journal of cell biology 1974;63(2 Pt 1):441-55.
1974: Nadler J V; Cotman C W; Lynch G S
Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.
Brain research 1974;79(3):465-75.
1974: Cotman C W; Taylor D
Localization and characterization of concanavalin A receptors in the synaptic cleft.
The Journal of cell biology 1974;62(1):236-42.
1974: Redburn D A; Cotman C W
Calcium-dependent release of (14C)GABA from vinblastine and colchicine treated synaptosomes.
Brain research 1974;73(3):550-7.
1974: Levy W B; Haycock J W; Cotman C W
Effects of polyvalent cations on stimulus-coupled secretion of (14C)-gamma-aminobutyric acid from isolated brain synaptosomes.
Molecular pharmacology 1974;10(3):438-49.
1974: Parnavelas J G; Lynch G; Brecha N; Cotman C W; Globus A
Spine loss and regrowth in hippocampus following deafferentation.
Nature 1974;248(443):71-3.
1974: Lynch G; Stanfield B; Parks T; Cotman C W
Evidence for selective post-lesion axonal growth in the dentate gyrus of the rat.
Brain research 1974;69(1):1-11.
1974: Nadler J V; Matthews D A; Cotman C W; Lynch G S
Development of cholinergic innervation in the hippocampal formation of the rat. II. Quantitative changes in choline acetyltransferase and acetylcholinesterase activities.
Developmental biology 1974;36(1):142-54.
1974: Matthews D A; Nadler J V; Lynch G S; Cotman C W
Development of cholinergic innervation in the hippocampal formation of the rat. I. Histochemical demonstration of acetylcholinesterase activity.
Developmental biology 1974;36(1):130-41.
1974: Lynch G; Gall C; Mensah P; Cotman C W
Horseradish peroxidase histochemistry: a new method for tracing efferent projections in the central nervous system.
Brain research 1974;65(3):373-80.
1974: Cotman C W
Isolation of synaptosomal and synaptic plasma membrane fractions.
Methods in enzymology 1974;31(Pt A):445-52.
1973: Churchill L; Banker G; Cotman C W
Gradient design to optimize rate zonal separations.
Analytical biochemistry 1973;56(2):370-82.
1973: Crain B; Cotman C; Taylor D; Lynch G
A quantitative electron microscopic study of synaptogenesis in the dentate gyrus of the rat.
Brain research 1973;63():195-204.
1973: Steward O; Cotman C; Lynch G
The nature of increased histochemical deposition of INT formazan in fields of degenerating synaptic terminals.
Brain research 1973;63():183-93.
1973: Cotman C W; Matthews D A; Taylor D; Lynch G
Synaptic rearrangement in the dentate gyrus: histochemical evidence of adjustments after lesions in immature and adult rats.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(12):3473-7.
1973: Nadler J V; Cotman C W; Lynch G S
Altered distribution of choline acetyltransferase and acetylcholinesterase activities in the developing rat dentate gyrus following entorhinal lesion.
Brain research 1973;63():215-20.
1973: Mosko S; Lynch G; Cotman C W
The distribution of septal projections to the hippocampus of the rat.
The Journal of comparative neurology 1973;152(2):163-74.
1973: Lynch G; Stanfield B; Cotman C W
Developmental differences in post-lesion axonal growth in the hippocampus.
Brain research 1973;59():155-68.
1973: Levy W B; Redburn D A; Cotman C W
Stimulus-coupled secretion of gamma-aminobutyric acid from rat brain synaptosomes.
Science (New York, N.Y.) 1973;181(100):676-8.
1973: Lynch G; Smith R L; Mensah P; Cotman C
Tracing the dentate gyrus mossy fiber system with horseradish peroxidase histochemistry.
Experimental neurology 1973;40(2):516-24.
1973: Steward O; Lynch G; Cotman C
Histochemical detection of orthograde degeneration in the central nervous system of the rat.
Brain research 1973;54():65-73.
1973: Lynch G S; Mosko S; Parks T; Cotman C W
Relocation and hyperdevelopment of the dentate gyrus commissural system after entorhinal lesions in immature rats.
Brain research 1973;50(1):174-8.
1973: Churchill L; Cotman C W
Analytical zonal centrifugation of synaptosomes and mitochondria from rat brain homogenates.
Neurobiology 1973;3(5):311-9.
1972: Cotman C W; Taylor D
Isolation and structural studies on synaptic complexes from rat brain.
The Journal of cell biology 1972;55(3):696-711.
1972: Doyle L C; Cotman C W
Analysis of myelin-synaptosomal interactions in sucrose and Ficoll-sucrose gradients.
Analytical biochemistry 1972;49(1):29-36.
1972: Banker G; Crain B; Cotman C W
Molecular weights of the polypeptide chains of synaptic plasma membranes.
Brain research 1972;42(2):508-13.
1972: Lynch G; Matthews D A; Mosko S; Parks T; Cotman C
Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions.
Brain research 1972;42(2):311-8.
1972: Herschman H R; Cotman C; Matthews D A
Serologic specificities of brain subcellular organelles. I. Antisera to synaptosomal fractions.
Journal of immunology (Baltimore, Md. : 1950) 1972;108(5):1362-9.
1972: Costin A; Cotman C; Hafemann D R; Herschmann H R
Effect of antibrain synaptosomal fraction serum and complement on evoked potentials and impedance.
Experientia 1972;28(4):411-2.
1971: Cotman C W; McCaman R E; Dewhurst S A
Subsynaptosomal distribution of enzymes involved in the metabolism of lipids.
Biochimica et biophysica acta 1971;249(2):395-405.
1971: Cotman C W; Matthews D A
Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization.
Biochimica et biophysica acta 1971;249(2):380-94.
1971: Cotman C W; Banker G; Levy W; Taylor D
An ultrastructural and chemical analysis of the effect of triton X-100 on synaptic plasma membranes.
Biochimica et biophysica acta 1971;249(2):406-18.
1971: Cotman C W; Banker G; Zornetzer S F; McGaugh J L
Electroshock effects on brain protein synthesis: relation to brain seizures and retrograde amnesia.
Science (New York, N.Y.) 1971;173(995):454-6.
1971: Cotman C W; Taylor D A
Autoradiographic analysis of protein synthesis in synaptosomal fractions.
Brain research 1971;29(2):366-72.
1971: Cotman C W; Taylor D A
Autoradiographic analysis of protein synthesis in synaptosomal fractions.
Brain research 1971;29(2):366-72.
1971: Nielsen T; Cotman C
The binding of diphenylhydantoin to brain and subcellular fractions.
European journal of pharmacology 1971;14(4):344-50.
1971: Banker G; Cotman C W
Characteristics of different amino acids as protein precursors in mouse brain: advantages of certain carboxyl-labeled amino acids.
Archives of biochemistry and biophysics 1971;142(2):565-73.
1971: Cotman C; Herschman H; Taylor D
Subcellular fractionation of cultured glial cells.
Journal of neurobiology 1971;2(2):169-80.
1970: Cotman C W; Flansburg D A
An analytical micro-method for electron microscopic study of the composition and sedimentation properties of subcellular fractions.
Brain research 1970;22(1):152-6.
1970: Cotman C; Brown D H; Harrell B W; Anderson N G
Analytical differential centrifugation: an analysis of the sedimentation properties of synaptosomes, mitochondria and lysosomes from rat brain homogenates.
Archives of biochemistry and biophysics 1970;136(2):436-47.
1969: Cotman C; Blank M L; Moehl A; Snyder F
Lipid composition of synaptic plasma membranes isolated from rat brain by zonal centrifugation.
Biochemistry 1969;8(11):4606-12.
1969: Birch H; Cotman C W; Thompson R F
Technique and instrumentation in physiological psychology.
The American psychologist 1969;24(3):264-7.
1968: Cotman C W; Mahler H R; Hugli T E
Isolation and characterization of insoluble proteins of the synaptic plasma membrane.
Archives of biochemistry and biophysics 1968;126(3):821-37.
1968: Cotman C; Mahler H R; Anderson N G
Isolation of a membrane fraction enriched in nerve-end membranes from rat brain by zonal cetrifugation.
Biochimica et biophysica acta 1968;163(2):272-5.
1967: Cotman C W; Mahler H R
Resolution of insoluble proteins in rat brain subcellular fractions.
Archives of biochemistry and biophysics 1967;120(2):384-96.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Carl Cotman

Research Profile (preview)

Living Beings

Anatomy

Disorders

Chemicals & Drugs

Procedures

Concepts & Ideas

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Carl Cotman (preview)

All Publications