FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Thomas Cotter

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Physiology

Procedures

In Situ Nick End Labelling

Phenomena

Blotting, Western

Co-author Network

Publications

TOP 3
Aoife Corcoran; Thomas G Cotter
Redox regulation of protein kinases.
William D Landry; John F Woolley; Thomas G Cotter
Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox.
Francesca Doonan; Thomas G Cotter
Detection of DNA fragmentation in retinal apoptosis by TUNEL.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Thomas Cotter (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Aoife Corcoran; Thomas G Cotter
Redox regulation of protein kinases.
The FEBS journal 2013;280(9):1944-65.
2013: William D Landry; John F Woolley; Thomas G Cotter
Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox.
Leukemia research 2013;37(2):183-9.
2013: Francesca Doonan; Thomas G Cotter
Detection of DNA fragmentation in retinal apoptosis by TUNEL.
Methods in molecular biology (Clifton, N.J.) 2013;935():207-13.
2013: Aoife Corcoran; Thomas G Cotter
FLT3-driven redox-modulation of Ezrin regulates leukaemic cell migration.
Free radical research 2013;47(1):20-34.
2012: Christopher A Pettigrew; John S Clerkin; Thomas G Cotter
DUOX enzyme activity promotes AKT signalling in prostate cancer cells.
Anticancer research 2012;32(12):5175-81.
2012: Gillian Groeger; Francesca Doonan; Thomas G Cotter; Maryanne Donovan
Reactive oxygen species regulate prosurvival ERK1/2 signaling and bFGF expression in gliosis within the retina.
Investigative ophthalmology & visual science 2012;53(10):6645-54.
2012: Francesca Doonan; Gillian Groeger; Thomas G Cotter
Preventing retinal apoptosis--is there a common therapeutic theme?
Experimental cell research 2012;318(11):1278-84.
2012: Francesca Doonan; Thomas G Cotter
Norgestrel may be a potential therapy for retinal degenerations.
Expert opinion on investigational drugs 2012;21(5):579-81.
2012: D Peter O'Leary; Lavinia Bhatt; Thomas G Cotter; David R Gough; Jiang H Wang; John F Woolley; H Paul Redmond
TLR-4 signalling accelerates colon cancer cell adhesion via NF-κB mediated transcriptional up-regulation of Nox-1.
PloS one 2012;7(10):e44176.
2012: John F Woolley; Lavinia Bhatt; Christopher J Chang; Bryan C Dickinson; David R Gough; Ruth Naughton; Joanna Stanicka; Thomas G Cotter
H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.
PloS one 2012;7(7):e34050.
2011: Daniel Alvira; Lavinia Bhatt; William D Landry; Ruth Naughton; Sara Tedesco; Thomas G Cotter
Inhibition of protein-tyrosine phosphatase 1B (PTP1B) mediates ubiquitination and degradation of Bcr-Abl protein.
The Journal of biological chemistry 2011;286(37):32313-23.
2011: Francesca Doonan; Paul Kenna; Caitriona M O'Driscoll; Thomas G Cotter
Enhancing survival of photoreceptor cells in vivo using the synthetic progestin Norgestrel.
Journal of neurochemistry 2011;118(5):915-27.
2011: Caitriona M O'Driscoll; Nuria Sanvicens; Francesca Doonan; Angel Messeguer; Thomas G Cotter
A novel free radical scavenger rescues retinal cells in vivo.
Experimental eye research 2011;93(1):65-74.
2011: Marc B Guerin; Maryanne Donovan; Declan P McKernan; Colm J O'brien; Thomas G Cotter
Age-dependent rat retinal ganglion cell susceptibility to apoptotic stimuli: implications for glaucoma.
Clinical & experimental ophthalmology 2011;39(3):243-51.
2011: Stephen M J Farrell; Gillian Groeger; Lavinia Bhatt; Sorcha Finnegan; Colm J O'brien; Thomas G Cotter
bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.
The European journal of neuroscience 2011;33(4):632-41.
2011: Maryanne Donovan; Francesca Doonan; Thomas G Cotter
Differential roles of ERK1/2 and JNK in retinal development and degeneration.
Journal of neurochemistry 2011;116(1):33-42.
2010: Sorcha Finnegan; Ashley M Mackey; Thomas G Cotter
A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A.
The European journal of neuroscience 2010;32(3):322-34.
2009: Gillian Groeger; Claire Quiney; Thomas G Cotter
Hydrogen peroxide as a cell-survival signaling molecule.
Antioxidants & redox signaling 2009;11(11):2655-71.
2009: Ana I Arroba; Deborah Wallace; Ashley Mackey; Enrique J de la Rosa; Thomas G Cotter
IGF-I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death.
The European journal of neuroscience 2009;30(6):975-86.
2009: Christopher A Pettigrew; Thomas G Cotter
Deregulation of cell death (apoptosis): implications for tumor development.
Discovery medicine 2009;8(41):61-3.
2009: R Naughton; C Quiney; S D Turner; Thomas G Cotter
Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway.
Leukemia 2009;23(8):1432-40.
2009: Thomas G Cotter
Apoptosis and cancer: the genesis of a research field.
Nature reviews. Cancer 2009;9(7):501-7.
2009: Gillian Groeger; Ashley M Mackey; Christopher A Pettigrew; Lavinia Bhatt; Thomas G Cotter
Stress-induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide.
Journal of neurochemistry 2009;109(5):1544-54.
2009: myles smith; Aedín C Culhane; M Donovan; J C Coffey; BD Barry; M A Kelly; Desmond G Higgins; Jiang Huai Wang; William O Kirwan; Thomas G Cotter; H Paul Redmond
Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification.
British journal of cancer 2009;100(9):1452-64.
2009: Francesca Doonan; Deborah M Wallace; Caitriona M O'Driscoll; Thomas G Cotter
Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2.
Journal of neurochemistry 2009;109(2):631-43.
2009: Deborah M Wallace; Thomas G Cotter
Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina.
Journal of neuroscience research 2009;87(4):887-905.
2008: myles smith; Aedín C Culhane; Shane Killeen; Maura A Kelly; Jiang H Wang; Thomas G Cotter; Henry P Redmond
Mechanisms driving local breast cancer recurrence in a model of breast-conserving surgery.
Annals of surgical oncology 2008;15(10):2954-64.
2008: Jeremy C O'Connor; Deborah M Wallace; Colm J O'brien; Thomas G Cotter
A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell.
Investigative ophthalmology & visual science 2008;49(10):4237-44.
2008: A M Mackey; Nuria Sanvicens; G Groeger; Francesca Doonan; D Wallace; Thomas G Cotter
Redox survival signalling in retina-derived 661W cells.
Cell death and differentiation 2008;15(8):1291-303.
2008: J S Clerkin; R Naughton; C Quiney; Thomas G Cotter
Mechanisms of ROS modulated cell survival during carcinogenesis.
Cancer letters 2008;266(1):30-6.
2008: Caitriona M O'Driscoll; Jeremy O'Connor; Colm J O'brien; Thomas G Cotter
Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.
Journal of neurochemistry 2008;105(2):524-36.
2008: Francesca Doonan; Thomas G Cotter
Morphological assessment of apoptosis.
Methods (San Diego, Calif.) 2008;44(3):200-4.
2008: Shane D Madden; Thomas G Cotter
Cell death in brain development and degeneration: control of caspase expression may be key!
Molecular neurobiology 2008;37(1):1-6.
2007: Declan P McKernan; Marc B Guerin; Colm J O'brien; Thomas G Cotter
A key role for calpains in retinal ganglion cell death.
Investigative ophthalmology & visual science 2007;48(12):5420-30.
2007: Caitriona M O'Driscoll; Deborah Wallace; Thomas G Cotter
bFGF promotes photoreceptor cell survival in vitro by PKA-mediated inactivation of glycogen synthase kinase 3beta and CREB-dependent Bcl-2 up-regulation.
Journal of neurochemistry 2007;103(3):860-70.
2007: Francesca Doonan; Maryanne Donovan; Violeta Gomez-Vicente; Philippe Bouillet; Thomas G Cotter
Bim expression indicates the pathway to retinal cell death in development and degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(40):10887-94.
2007: Declan P McKernan; Thomas G Cotter
A Critical role for Bim in retinal ganglion cell death.
Journal of neurochemistry 2007;102(3):922-30.
2007: Shane D Madden; Maryanne Donovan; Thomas G Cotter
Key apoptosis regulating proteins are down-regulated during postnatal tissue development.
The International journal of developmental biology 2007;51(5):415-23.
2006: Caitriona M O'Driscoll; Maryanne Donovan; Thomas G Cotter
Analysis of apoptotic and survival mediators in the early post-natal and mature retina.
Experimental eye research 2006;83(6):1482-92.
2006: Nuria Sanvicens; Paul Galvin; Thomas G Cotter
Multiplex analysis with peptide-encoded beads.
Bioconjugate chemistry 2006;17(6):1607-11.
2006: Karen England; Carolyn O Driscoll; Thomas G Cotter
ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis.
Free radical research 2006;40(11):1124-37.
2006: Nuria Sanvicens; Thomas G Cotter
Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.
Journal of neurochemistry 2006;98(5):1432-44.
2006: Violeta Gómez-Vicente; Francesca Doonan; Maryanne Donovan; Thomas G Cotter
Induction of BIM(EL) following growth factor withdrawal is a key event in caspase-dependent apoptosis of 661W photoreceptor cells.
The European journal of neuroscience 2006;24(4):981-90.
2006: Nuria Sanvicens; Violeta Gómez-Vicente; Angel Messeguer; Thomas G Cotter
The radical scavenger CR-6 protects SH-SY5Y neuroblastoma cells from oxidative stress-induced apoptosis: effect on survival pathways.
Journal of neurochemistry 2006;98(3):735-47.
2006: Deborah M Wallace; Maryanne Donovan; Thomas G Cotter
Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina.
Investigative ophthalmology & visual science 2006;47(7):2765-72.
2006: Katarzyna Piwocka; Susanne Vejda; Thomas G Cotter; Gerald C O'Sullivan; Sharon L McKenna
Bcr-Abl reduces endoplasmic reticulum releasable calcium levels by a Bcl-2-independent mechanism and inhibits calcium-dependent apoptotic signaling.
Blood 2006;107(10):4003-10.
2006: Fionnuala Hickey; Thomas G Cotter
Identification of transcriptional targets associated with the expression of p210 Bcr-Abl.
European journal of haematology 2006;76(5):369-83.
2006: Declan P McKernan; Ciara Caplis; Maryanne Donovan; Colm J O'brien; Thomas G Cotter
Age-dependent susceptibility of the retinal ganglion cell layer to cell death.
Investigative ophthalmology & visual science 2006;47(3):807-14.
2006: Maryanne Donovan; Francesca Doonan; Thomas G Cotter
Decreased expression of pro-apoptotic Bcl-2 family members during retinal development and differential sensitivity to cell death.
Developmental biology 2006;291(1):154-69.
2006: Fionnuala Hickey; Thomas G Cotter
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.
The Journal of biological chemistry 2006;281(5):2441-50.
2006: J Calvin Coffey; Jiang H Wang; David Bouchier-Hayes; Thomas G Cotter; H Paul Redmond
The targeting of phosphoinositide-3 kinase attenuates pulmonary metastatic tumor growth following laparotomy.
Annals of surgery 2006;243(2):250-6.
2006: Marc B Guerin; Declan P McKernan; Colm J O'brien; Thomas G Cotter
Retinal ganglion cells: dying to survive.
The International journal of developmental biology 2006;50(8):665-74.
2005: James Hynes; Tomás C O'Riordan; James Curtin; Thomas G Cotter; Dmitri B Papkovsky
Fluorescence based oxygen uptake analysis in the study of metabolic responses to apoptosis induction.
Journal of immunological methods 2005;306(1-2):193-201.
2005: Francesca Doonan; Maryanne Donovan; Thomas G Cotter
Activation of multiple pathways during photoreceptor apoptosis in the rd mouse.
Investigative ophthalmology & visual science 2005;46(10):3530-8.
2005: Fionnuala Hickey; Karen England; Thomas G Cotter
Bcr-Abl regulates osteopontin transcription via Ras, PI-3K, aPKC, Raf-1, and MEK.
Journal of leukocyte biology 2005;78(1):289-300.
2005: Violeta Gómez-Vicente; Maryanne Donovan; Thomas G Cotter
Multiple death pathways in retina-derived 661W cells following growth factor deprivation: crosstalk between caspases and calpains.
Cell death and differentiation 2005;12(7):796-804.
2005: J Calvin Coffey; Jiang Huai Wang; myles smith; Alan Laing; David Bouchier-Hayes; Thomas G Cotter; H Paul Redmond
Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy.
The Journal of biological chemistry 2005;280(22):20968-77.
2005: Susanne Vejda; Katarzyna Piwocka; Sharon L McKenna; Thomas G Cotter
Autocrine secretion of osteopontin results in degradation of I kappa B in Bcr-Abl-expressing cells.
British journal of haematology 2005;128(5):711-21.
2005: Karen England; Thomas G Cotter
Direct oxidative modifications of signalling proteins in mammalian cells and their effects on apoptosis.
Redox report : communications in free radical research 2005;10(5):237-45.
2004: Nuria Sanvicens; Violeta Gómez-Vicente; Isabel Masip; Angel Messeguer; Thomas G Cotter
Oxidative stress-induced apoptosis in retinal photoreceptor cells is mediated by calpains and caspases and blocked by the oxygen radical scavenger CR-6.
The Journal of biological chemistry 2004;279(38):39268-78.
2004: Karen England; Thomas G Cotter
Identification of carbonylated proteins by MALDI-TOF mass spectroscopy reveals susceptibility of ER.
Biochemical and biophysical research communications 2004;320(1):123-30.
2004: V Duverger; A-M Murphy; David Sheehan; Karen England; Thomas G Cotter; Ian Hayes; Finbarr J Murphy
The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF).
British journal of cancer 2004;90(10):2025-31.
2004: James F Curtin; Thomas G Cotter
JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells.
The Journal of biological chemistry 2004;279(17):17090-100.
2004: Maryanne Donovan; Thomas G Cotter
Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death.
Biochimica et biophysica acta 2004;1644(2-3):133-47.
2004: Karen England; Caitriona M O'Driscoll; Thomas G Cotter
Carbonylation of glycolytic proteins is a key response to drug-induced oxidative stress and apoptosis.
Cell death and differentiation 2004;11(3):252-60.
2004: Loraine M Smith; patrick walsh; Thomas Rüdiger; Thomas G Cotter; Tommie V Mc Carthy; Alexander Marx; Rosemary O'Connor
EphA3 is induced by CD28 and IGF-1 and regulates cell adhesion.
Experimental cell research 2004;292(2):295-303.
2004: Francesca Doonan; Thomas G Cotter
Apoptosis: a potential therapeutic target for retinal degenerations.
Current neurovascular research 2004;1(1):41-53.
2003: James F Curtin; Thomas G Cotter
Defects in death-inducing signalling complex formation prevent JNK activation and Fas-mediated apoptosis in DU 145 prostate carcinoma cells.
British journal of cancer 2003;89(10):1950-7.
2003: James F Curtin; Thomas G Cotter
Live and let die: regulatory mechanisms in Fas-mediated apoptosis.
Cellular signalling 2003;15(11):983-92.
2003: Karen Keeshan; Thomas G Cotter; Sharon L McKenna
Bcr-Abl upregulates cytosolic p21WAF-1/CIP-1 by a phosphoinositide-3-kinase (PI3K)-independent pathway.
British journal of haematology 2003;123(1):34-44.
2003: Finbarr J Murphy; Ian Hayes; Thomas G Cotter
Targeting inflammatory diseases via apoptotic mechanisms.
Current opinion in pharmacology 2003;3(4):412-9.
2003: Francesca Doonan; Maryanne Donovan; Thomas G Cotter
Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5723-31.
2003: James F Curtin; Thomas G Cotter
Apoptosis: Historical perspectives.
Essays in biochemistry 2003;39():1-10.
2002: Aedín C Culhane; Guy Perrière; Elizabeth C Considine; Thomas G Cotter; Desmond G Higgins
Between-group analysis of microarray data.
Bioinformatics (Oxford, England) 2002;18(12):1600-8.
2002: James F Curtin; Thomas G Cotter
Anisomycin activates JNK and sensitises DU 145 prostate carcinoma cells to Fas mediated apoptosis.
British journal of cancer 2002;87(10):1188-94.
2002: Maryanne Donovan; Thomas G Cotter
Caspase-independent photoreceptor apoptosis in vivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development.
Cell death and differentiation 2002;9(11):1220-31.
2002: Karen Keeshan; Thomas G Cotter; Sharon L McKenna
High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion.
Leukemia 2002;16(9):1725-34.
2002: James F Curtin; Maryanne Donovan; Thomas G Cotter
Regulation and measurement of oxidative stress in apoptosis.
Journal of immunological methods 2002;265(1-2):49-72.
2002: Alessandra M A Di Bacco; Thomas G Cotter
p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases.
British journal of haematology 2002;117(3):588-97.
2002: Melanie Walsh; Robert J Lutz; Thomas G Cotter; Rosemary O'Connor
Erythrocyte survival is promoted by plasma and suppressed by a Bak-derived BH3 peptide that interacts with membrane-associated Bcl-X(L).
Blood 2002;99(9):3439-48.
2001: Karen Keeshan; Ken Mills; Thomas G Cotter; Sharon L McKenna
Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype.
Leukemia 2001;15(12):1823-33.
2001: C N O'Donovan; D Tobin; Thomas G Cotter
Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells.
The Journal of biological chemistry 2001;276(47):43516-23.
2001: Denise O'Gorman; Sharon L McKenna; AJ McGahon; Thomas G Cotter
Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis by a JNK independent pathway.
Leukemia research 2001;25(9):801-11.
2001: N M Finnegan; James F Curtin; Grégoire Prevost; B Morgan; Thomas G Cotter
Induction of apoptosis in prostate carcinoma cells by BH3 peptides which inhibit Bak/Bcl-2 interactions.
British journal of cancer 2001;85(1):115-21.
2001: Maryanne Donovan; Ruaidhrí J Carmody; Thomas G Cotter
Light-induced photoreceptor apoptosis in vivo requires neuronal nitric-oxide synthase and guanylate cyclase activity and is caspase-3-independent.
The Journal of biological chemistry 2001;276(25):23000-8.
2001: Marian Humphries; S Kiang; Niamh McNally; M A Donovan; Paul Sieving; Ronald A Bush; S Machida; Thomas G Cotter; AH Hobson; J Farrar; Peter Humphries; Paul F Kenna
Comparative structural and functional analysis of photoreceptor neurons of Rho-/- mice reveal increased survival on C57BL/6J in comparison to 129Sv genetic background.
Visual neuroscience 2001;18(3):437-43.
2001: Ruaidhrí J Carmody; Thomas G Cotter
Signalling apoptosis: a radical approach.
Redox report : communications in free radical research 2001;6(2):77-90.
2001: Denise O'Gorman; Thomas G Cotter
Molecular signals in anti-apoptotic survival pathways.
Leukemia 2001;15(1):21-34.
2000: AH Hobson; M Donovan; Marian Humphries; Gearóid Tuohy; Niamh McNally; Ruaidhrí J Carmody; Thomas G Cotter; G Jane Farrar; Paul F Kenna; Peter Humphries
Apoptotic photoreceptor death in the rhodopsin knockout mouse in the presence and absence of c-fos.
Experimental eye research 2000;71(3):247-54.
2000: EM Creagh; D Sheehan; Thomas G Cotter
Heat shock proteins--modulators of apoptosis in tumour cells.
Leukemia 2000;14(7):1161-73.
2000: AP Costa Pereira; Sharon L McKenna; Thomas G Cotter
Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis.
British journal of cancer 2000;82(11):1827-34.
2000: EM Creagh; Ruaidhrí J Carmody; Thomas G Cotter
Heat shock protein 70 inhibits caspase-dependent and -independent apoptosis in Jurkat T cells.
Experimental cell research 2000;257(1):58-66.
2000: Denise O'Gorman; Sharon L McKenna; AJ McGahon; K A Knox; Thomas G Cotter
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Leukemia 2000;14(4):602-11.
2000: Ruaidhrí J Carmody; Thomas G Cotter
Oxidative stress induces caspase-independent retinal apoptosis in vitro.
Cell death and differentiation 2000;7(3):282-91.
2000: Sharon L McKenna; Thomas G Cotter
Inhibition of caspase activity delays apoptosis in a transfected NS/0 myeloma cell line.
Biotechnology and bioengineering 2000;67(2):165-76.
2000: R J Carmody; AP Costa Pereira; Sharon L McKenna; Thomas G Cotter
Detection of molecular events during apoptosis by flow cytometry.
Methods in molecular medicine 2000;38():71-83.
2000: A Di Bacco; Karen Keeshan; Sharon L McKenna; Thomas G Cotter
Molecular abnormalities in chronic myeloid leukemia: deregulation of cell growth and apoptosis.
The oncologist 2000;5(5):405-15.
1999: G P Devitt; EM Creagh; Thomas G Cotter
The antioxidant 4b,5,9b,10-Tetrahydroindeno[1,2-b]indole inhibits apoptosis by preventing caspase activation following mitochondrial depolarization.
Biochemical and biophysical research communications 1999;264(3):622-9.
1999: Noel Fanning; J Porter; George D Shorten; William O Kirwan; David Bouchier-Hayes; Thomas G Cotter; H Paul Redmond
Inhibition of neutrophil apoptosis after elective surgery.
Surgery 1999;126(3):527-34.
1999: DM Finucane; Nigel Waterhouse; Gustavo Amarante-Mendes; Thomas G Cotter; Douglas R Green
Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.
Experimental cell research 1999;251(1):166-74.
1999: EM Creagh; Thomas G Cotter
Selective protection by hsp 70 against cytotoxic drug-, but not Fas-induced T-cell apoptosis.
Immunology 1999;97(1):36-44.
1999: AP Costa Pereira; Thomas G Cotter
Camptothecin sensitizes androgen-independent prostate cancer cells to anti-Fas-induced apoptosis.
British journal of cancer 1999;80(3-4):371-8.
1999: Ruaidhrí J Carmody; AJ McGowan; Thomas G Cotter
Reactive oxygen species as mediators of photoreceptor apoptosis in vitro.
Experimental cell research 1999;248(2):520-30.
1999: Noel Fanning; Malcolm R Kell; George D Shorten; William O Kirwan; David Bouchier-Hayes; Thomas G Cotter; H Paul Redmond
Circulating granulocyte macrophage colony-stimulating factor in plasma of patients with the systemic inflammatory response syndrome delays neutrophil apoptosis through inhibition of spontaneous reactive oxygen species generation.
Shock (Augusta, Ga.) 1999;11(3):167-74.
1999: Adrienne M Gorman; B Heavey; EM Creagh; Thomas G Cotter; Afshin Samali
Antioxidant-mediated inhibition of the heat shock response leads to apoptosis.
FEBS letters 1999;445(1):98-102.
1999: DM Finucane; Ella Bossy-Wetzel; Nigel Waterhouse; Thomas G Cotter; Douglas R Green
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.
The Journal of biological chemistry 1999;274(4):2225-33.
1998: Ruaidhrí J Carmody; AJ McGowan; Thomas G Cotter
Rapid detection of rod photoreceptor apoptosis by flow cytometry.
Cytometry 1998;33(1):89-92.
1998: AJ McGahon; AP Costa Pereira; L Daly; Thomas G Cotter
Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system.
British journal of haematology 1998;101(3):539-47.
1998: Gustavo Amarante-Mendes; DM Finucane; Seamus Martin; Thomas G Cotter; Guy S Salvesen; Douglas R Green
Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death.
Cell death and differentiation 1998;5(4):298-306.
1998: AJ McGowan; A G Bowie; L A O'Neill; Thomas G Cotter
The production of a reactive oxygen intermediate during the induction of apoptosis by cytotoxic insult.
Experimental cell research 1998;238(1):248-56.
1998: Sharon L McKenna; AJ McGowan; Thomas G Cotter
Molecular mechanisms of programmed cell death.
Advances in biochemical engineering/biotechnology 1998;62():1-31.
1997: Justin V McCarthy; Thomas G Cotter
Cell shrinkage and apoptosis: a role for potassium and sodium ion efflux.
Cell death and differentiation 1997;4(8):756-70.
1997: Adrienne M Gorman; Afshin Samali; AJ McGowan; Thomas G Cotter
Use of flow cytometry techniques in studying mechanisms of apoptosis in leukemic cells.
Cytometry 1997;29(2):97-105.
1997: Afshin Samali; B Gilje; Stein Ove Døskeland; Thomas G Cotter; Gunnar Houge
The ability to cleave 28S ribosomal RNA during apoptosis is a cell-type dependent trait unrelated to DNA fragmentation.
Cell death and differentiation 1997;4(4):289-93.
1997: Adrienne M Gorman; AJ McGowan; Thomas G Cotter
Role of peroxide and superoxide anion during tumour cell apoptosis.
FEBS letters 1997;404(1):27-33.
1997: AJ McGahon; D G Brown; Seamus Martin; Gustavo Amarante-Mendes; Thomas G Cotter; G M Cohen; Douglas R Green
Downregulation of Bcr-Abl in K562 cells restores susceptibility to apoptosis: characterization of the apoptotic death.
Cell death and differentiation 1997;4(2):95-104.
1997: Afshin Samali; Adrienne M Gorman; Thomas G Cotter
Role of Bcr-Abl kinase in resistance to apoptosis.
Advances in pharmacology (San Diego, Calif.) 1997;41():533-52.
1997: Sharon L McKenna; Thomas G Cotter
Functional aspects of apoptosis in hematopoiesis and consequences of failure.
Advances in cancer research 1997;71():121-64.
1996: Afshin Samali; Adrienne M Gorman; Thomas G Cotter
Apoptosis -- the story so far....
Experientia 1996;52(10-11):933-41.
1996: AJ McGowan; M C Ruiz-Ruiz; Adrienne M Gorman; A Lopez-Rivas; Thomas G Cotter
Reactive oxygen intermediate(s) (ROI): common mediator(s) of poly(ADP-ribose)polymerase (PARP) cleavage and apoptosis.
FEBS letters 1996;392(3):299-303.
1996: R S Fernandes; AJ McGowan; Thomas G Cotter
Mutant H-ras overexpression inhibits drug and U.V. induced apoptosis.
Anticancer research 1996;16(4A):1691-705.
1996: R S Fernandes; A M Gorman; AJ McGahon; M Lawlor; S McCann; Thomas G Cotter
The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia.
Leukemia 1996;10 Suppl 2():s17-21.
1996: Afshin Samali; Thomas G Cotter
Heat shock proteins increase resistance to apoptosis.
Experimental cell research 1996;223(1):163-70.
1996: AJ McGowan; R S Fernandes; Afshin Samali; Thomas G Cotter
Anti-oxidants and apoptosis.
Biochemical Society transactions 1996;24(1):229-33.
1995: S Verhaegen; AJ McGowan; A R Brophy; R S Fernandes; Thomas G Cotter
Inhibition of apoptosis by antioxidants in the human HL-60 leukemia cell line.
Biochemical pharmacology 1995;50(7):1021-9.
1995: AJ McGahon; W K Nishioka; Seamus Martin; Artin Mahboubi; Thomas G Cotter; Douglas R Green
Regulation of the Fas apoptotic cell death pathway by Abl.
The Journal of biological chemistry 1995;270(38):22625-31.
1995: Thomas G Cotter
BCR-ABL: an anti-apoptosis gene in chronic myelogenous leukemia.
Leukemia & lymphoma 1995;18(3-4):231-6.
1994: Thomas G Cotter; R S Fernandes; S Verhaegen; J V McCarthy
Cell death in the myeloid lineage.
Immunological reviews 1994;142():93-112.
1994: AJ McGowan; R S Fernandes; S Verhaegen; Thomas G Cotter
Zinc inhibits UV radiation-induced apoptosis but fails to prevent subsequent cell death.
International journal of radiation biology 1994;66(4):343-9.
1994: R S Fernandes; Thomas G Cotter
Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death.
Biochemical pharmacology 1994;48(4):675-81.
1994: Thomas G Cotter; J McCarthy
Genes and apoptosis.
Biochemical Society transactions 1994;22(3):591-3.
1994: AJ McGahon; Reid P Bissonnette; Manfred Schmitt; K M Cotter; Douglas R Green; Thomas G Cotter
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death.
Blood 1994;83(5):1179-87.
1994: Douglas R Green; Reid P Bissonnette; Thomas G Cotter
Apoptosis and cancer.
Important advances in oncology 1994;():37-52.
1993: R S Fernandes; Thomas G Cotter
Activation of a calcium magnesium independent endonuclease in human leukemic cell apoptosis.
Anticancer research 1993;13(5A):1253-9.
1993: C D Helgason; L Shi; A H Greenberg; Y Shi; P Bromley; Thomas G Cotter; Douglas R Green; R Chris Bleackley
DNA fragmentation induced by cytotoxic T lymphocytes can result in target cell death.
Experimental cell research 1993;206(2):302-10.
1992: Thomas G Cotter
Induction of apoptosis in cells of the immune system by cytotoxic stimuli.
Seminars in immunology 1992;4(6):399-405.
1992: Y Shi; J M Glynn; L J Guilbert; Thomas G Cotter; Reid P Bissonnette; Douglas R Green
Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas.
Science (New York, N.Y.) 1992;257(5067):212-4.
1992: Thomas G Cotter; J M Glynn; F Echeverri; Douglas R Green
The induction of apoptosis by chemotherapeutic agents occurs in all phases of the cell cycle.
Anticancer research 1992;12(3):773-9.
1992: S V Lennon; S A Kilfeather; M B Hallett; A K Campbell; Thomas G Cotter
Elevations in cytosolic free Ca2+ are not required to trigger apoptosis in human leukaemia cells.
Clinical and experimental immunology 1992;87(3):465-71.
1992: Thomas G Cotter; S V Lennon; J M Glynn; Douglas R Green
Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis.
Cancer research 1992;52(4):997-1005.
1992: J M Glynn; Thomas G Cotter; D R Green
Apoptosis induced by Actinomycin D, Camptothecin or Aphidicolin can occur in all phases of the cell cycle.
Biochemical Society transactions 1992;20(1):84S.
1992: S V Lennon; Thomas G Cotter
The regulatory role of zinc in apoptosis in human tumour cell lines.
Biochemical Society transactions 1992;20(1):78S.
1992: S V Lennon; S A Kilfeather; Thomas G Cotter
The role of calcium in the induction of apoptosis in human tumour cell lines.
Biochemical Society transactions 1992;20(1):77S.
1991: Seamus Martin; Thomas G Cotter
Ultraviolet B irradiation of human leukaemia HL-60 cells in vitro induces apoptosis.
International journal of radiation biology 1991;59(4):1001-16.
1991: S V Lennon; Seamus Martin; Thomas G Cotter
Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.
Cell proliferation 1991;24(2):203-14.
1991: Seamus Martin; G Mazdai; J J Strain; Thomas G Cotter; B M Hannigan
Programmed cell death (apoptosis) in lymphoid and myeloid cell lines during zinc deficiency.
Clinical and experimental immunology 1991;83(2):338-43.
1990: Seamus Martin; Thomas G Cotter
Disruption of microtubules induces an endogenous suicide pathway in human leukaemia HL-60 cells.
Cell and tissue kinetics 1990;23(6):545-59.
1990: Seamus Martin; S V Lennon; A M Bonham; Thomas G Cotter
Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1859-67.
1990: Thomas G Cotter; S V Lennon; J G Glynn; Seamus Martin
Cell death via apoptosis and its relationship to growth, development and differentiation of both tumour and normal cells.
Anticancer research 1990;10(5A):1153-9.
1990: Seamus Martin; A M Bonham; Thomas G Cotter
The involvement of RNA and protein synthesis in programmed cell death (apoptosis) in human leukaemia HL-60 cells.
Biochemical Society transactions 1990;18(4):634-6.
1990: R M Weedle; Thomas G Cotter
Biochemical studies on a human leukaemia-associated antigen.
Biochemical Society transactions 1990;18(2):345-6.
1990: S V Lennon; Seamus Martin; Thomas G Cotter
Induction of apoptosis (programmed cell death) in tumour cell lines by widely diverging stimuli.
Biochemical Society transactions 1990;18(2):343-5.
1990: Seamus Martin; Thomas G Cotter
Specific loss of microtubules in HL-60 cells leads to programmed cell death (apoptosis).
Biochemical Society transactions 1990;18(2):299-301.
1990: Thomas G Cotter
The granulocyte cell surface during differentiation.
Biochemical Society transactions 1990;18(2):228-9.
1990: Seamus Martin; J G Bradley; Thomas G Cotter
HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis.
Clinical and experimental immunology 1990;79(3):448-53.
1990: R M Weedle; Thomas G Cotter
Biochemical characterisation studies on a leukocyte alloantigen expressed with high frequency in leukaemia patients.
Leukemia research 1990;14(9):761-70.
1989: R O'Connor; J G Bradley; A O'Meara; Thomas G Cotter
Identification of a leukocyte alloantigen with a high-frequency expression in leukemia patients.
Blood 1989;73(2):553-8.
1988: L C Meagher; Thomas G Cotter
The degranulation response in differentiated HL-60 cells.
Clinical and experimental immunology 1988;74(3):483-8.
1987: R O'Connor; J G Bradley; E Lawlor; Thomas G Cotter
Production and characterization of a monoclonal antibody to a myeloid specific differentiation antigen.
Leukemia research 1987;11(5):481-8.