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Les Coulton

Research Profile

Disorders

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Anatomy

Osteoclasts

Chemicals & Drugs

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Publications

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Sarah Deleu; Miguel Lemaire; Janine Arts; Eline Menu; Els Van Valckenborgh; Isabelle Vande Broek; Hendrik De Raeve; Les Coulton; Ben Van Camp; Peter I Croucher; Karin Vanderkerken
Bortezomib alone or in combination with the histone deacetylase inhibitor JNJ-26481585: effect on myeloma bone disease in the 5T2MM murine model of myeloma.
Eline Menu; Helena Jernberg-Wiklund; Hendrik De Raeve; Evy De Leenheer; Les Coulton; Orla Gallagher; Els Van Valckenborgh; Olle Larsson; Magnus Axelson; Kenneth Nilsson; Ben Van Camp; Peter I Croucher; Karin Vanderkerken
Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival.
N Rabin; Charalampia Kyriakou; Les Coulton; Orla Gallagher; C Buckle; Reuben Benjamin; Nalini Singh; Janet Glassford; T Otsuki; Amit C Nathwani; Peter I Croucher; Kwee Yong
A new xenograft model of myeloma bone disease demonstrating the efficacy of human mesenchymal stem cells expressing osteoprotegerin by lentiviral gene transfer.

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All Publications

2009: Sarah Deleu; Miguel Lemaire; Janine Arts; Eline Menu; Els Van Valckenborgh; Isabelle Vande Broek; Hendrik De Raeve; Les Coulton; Ben Van Camp; Peter I Croucher; Karin Vanderkerken
Bortezomib alone or in combination with the histone deacetylase inhibitor JNJ-26481585: effect on myeloma bone disease in the 5T2MM murine model of myeloma.
Cancer research 2009;69(13):5307-11.
2007: Eline Menu; Helena Jernberg-Wiklund; Hendrik De Raeve; Evy De Leenheer; Les Coulton; Orla Gallagher; Els Van Valckenborgh; Olle Larsson; Magnus Axelson; Kenneth Nilsson; Ben Van Camp; Peter I Croucher; Karin Vanderkerken
Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival.
International journal of cancer. Journal international du cancer 2007;121(8):1857-61.
2007: N Rabin; Charalampia Kyriakou; Les Coulton; Orla Gallagher; C Buckle; Reuben Benjamin; Nalini Singh; Janet Glassford; T Otsuki; Amit C Nathwani; Peter I Croucher; Kwee Yong
A new xenograft model of myeloma bone disease demonstrating the efficacy of human mesenchymal stem cells expressing osteoprotegerin by lentiviral gene transfer.
Leukemia 2007;21(10):2181-91.
2007: Karin Vanderkerken; Satyanarayana Medicherla; Les Coulton; Hendrik De Raeve; Angelo Willems; Michelle Lawson; Ben Van Camp; Protter Andrew; Linda S Higgins; Eline Menu; Peter I Croucher
Inhibition of p38alpha mitogen-activated protein kinase prevents the development of osteolytic bone disease, reduces tumor burden, and increases survival in murine models of multiple myeloma.
Cancer research 2007;67(10):4572-7.
2006: Eline Menu; Evy De Leenheer; Hendrik De Raeve; Les Coulton; Takeshi Imanishi; Kazuyuki Miyashita; Els Van Valckenborgh; Ivan Van Riet; Ben Van Camp; Richard Horuk; Peter I Croucher; Karin Vanderkerken
Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model.
Clinical & experimental metastasis 2006;23(5-6):291-300.